Digital Commons Network^™

Uncertainty-Guided Test-Time Optimization For Personalizing Segmentation Models In Longitudinal Medical Imaging, Jaehee Chun, Austin Castelo, Mckell Woodland, Caleb O'Connor, Mais Al Taie, Mohamed Eltaher, Aashish Gupta, Bilel Daoud, Shanli Ding, Jeddy Bennett, Anirban Maitra, Matthew A Firpo, Kimberly Kirkwood, Eugene J Koay, Kristy K Brock

Faculty, Staff and Student Publications

Background: Accurate and consistent image segmentation across longitudinal scans is essential in many clinical applications, including surveillance, treatment monitoring, and adaptive interventions. While personalized model adaptation using patient-specific prior scans has shown promise, current approaches typically rely on fixed training durations and lack mechanisms to determine optimal stopping points on a per-patient basis, particularly in the absence of validation labels.

Purpose: We propose an uncertainty-guided test-time optimization (TTO) framework that dynamically adjusts the personalization duration for each patient using a validation-free stopping criterion based on predictive uncertainty.

Methods: Our framework personalizes a generalized segmentation model using patient-specific prior imaging and …

The Effects Of Fitness Self-Testing With Instant Feedback On Changes In Health-Related Fitness Among Chinese Male College Students, Yongshun Wang, Xiaofen D Hamilton, Rulan Shangguan, Anlu Yang, Na Xiao, Chenhao Wu, Sizhe Liu, Ren Yang, Jiren Zhang, Mark F Hamilton

Faculty, Staff and Student Publications

Background: The decline in health-related physical fitness resulting from physical inactivity remains a critical global public health concern. Technology-supported fitness self-testing has the potential not only to improve students' testing experiences but also to enhance their health-related fitness. However, the effectiveness of such approaches has not yet been systematically examined, and their validity within university populations remains largely unestablished.

Method: A quasi-experimental research design with a control group (n = 45) and an experimental group (n = 44), incorporating pre- and post-tests, was employed in this study. The experimental group completed monthly self-testing sessions accompanied by GAI-generated instant feedback over …

From Perspectival Myopia To Professional Transformation: An Autoethnographic Retrospection Of A High School Principal From Nepal, Shankar Dhakal, Geoffrey W. Lummis, Andrew Jones

Research outputs 2022 to 2026

This paper presents a re-storied account of my (lead author) decade-long (2007–2017) professional journey as a high school principal in diverse educational settings in Nepal. Using an autoethnographic approach, I have theorized my leadership transformation approaches through professional storytelling, employing critical reflexivity to trace intimate leadership experiences where authoritarian approaches to leadership, disparities, and inequalities in schools run rampant. My perspectival myopia, professional vulnerabilities, and the discrepancies between my leadership ideals and behaviors resulted in issues such as perceptions of disengagement, underperformance, and dissatisfaction on the receiving end, prompting me to contemplate professional transformation. While outlining several significant steps and …

The Hows And Whys Of Gendered Grouping Practices In Primary Physical Education In England, Shaun D. Wilkinson, Annette Stride, Dawn Penney

Research outputs 2022 to 2026

Background: Single- and mixed-sex grouping have long been a focus of attention in physical education (PE) and are matters often at the fore of discussions about curriculum planning, teaching, and learning. Nonetheless, there remains little consensus or guidance on which approach (or combination of approaches) should be preferred in PE in primary and secondary schools in England. Further, while single- and mixed-sex grouping have been extensively researched in PE in secondary schools, hitherto there remains an absence of research examining these practices in PE in primary schools. This research sought to address gaps in the literature to build a stronger …

Non-Destructive Characterization Of Variously Colored Gypsum And Aragonite/Calcite Speleothems From The Cigalère Cave (Ariège, France), Martin Vlieghe, Johan Wouters, Gérald Fanuel, Jean-François Drion Du Chapois, Anne Gallez, Stéphane Pire-Stevenne, Gaëtan Rochez, Johan Yans

International Journal of Speleology

The Cigalère Cave is a 21 km-long karstic cave located in the Ariège Department, in the French Pyrenees, and underlies directly the Bentaillou Pb-Zn-Fe sulfide ores. The cave hosts abundant gypsum mineralizations, some of them exhibiting various colorations including blue, yellow, purple, orange and black. Due to strict preservation policies, these colored mineralizations have not been studied much. Here we propose a non-destructive characterization of five distinct gypsum or carbonate speleothem structures from the Cigalère, exhibiting different colorations. To comply with the preservation policies, no sample was taken from the cave, and all speleothems were analyzed in situ using portable …

Elephant Economics And Agrarian Transitions: Conditions For Benefiting From Elephant Tourism Market In An Upland Karen (Paganyaw) Village, Xiaoyun Neo, Aswin Baharuddin, Nur Fadilah Sunardi

Forest and Society

In rural, upland northern Thailand, Indigenous Karen (Paganyaw) communities have long practiced diversified subsistence cultivation and forest-based livelihoods. Yet state conservation policies and tourism-led development are reshaping these agrarian systems and livelihoods. This paper explores how one Karen (Paganyaw) community in Chiang Mai province reconfigures its livelihood strategies amid the decline of swidden cultivation and the rise of elephant tourism as a new rural economy. Beyond subsistence cultivation, villagers are seeking to diversify their households and personal income by participating in this new economic sector. We argue that the transition out of small-scale agriculture into tourism is not a neutral …

The Unequal Partnership Behind Biodiversity Conservation Efforts In The Eastern Democratic Republic Of Congo, Alexandra Rasoamanana, Eliezer Majambu, Dominique Bikaba, Symphorien Ongolo, Emilie Dupuits

Forest and Society

The growing demand for inclusivity in conservation has led international conservation organisations (ICOs) to collaborate more with local conservation organisations (LCOs). This paper assesses such partnerships through a community-led initiative establishing a wildlife corridor between Maiko and Kahuzi-Biega National Parks. In this region, resource conflicts are often cited as a political justification for recurring conservation failures. However, this framing overlooks crucial questions about how fairness and sustainability in conservation are constructed in practice, particularly within contested forestlands where multiple groups claim legitimacy over ownership. We analyse the structural conditions that enable or constrain the formation of authentic partnerships. Such partnerships …

The Disenchanted Grove: Postcolonial Modernity And The Decline Of Ri’I Bamboo Governance In Flores, Indonesia, Handoyo Handoyo, Puji Hastuti, Lukas Rumboko Wibowo, Budiyanto Dwi Prasetyo, Surati Surati, Kresno Agus Hendarto, Lila Juniyanti, Dewi Ratna Kurnia Sari, Desmiwati Desmiwati, Sanusi Sanusi, Ane Dwi Septina, Ramawati Ramawati

Forest and Society

This article explores the erosion of ri’i, a traditional ecological governance system practiced by the Ngadha people in Flores, Indonesia, in the face of modernization and postcolonial development. Based on long-term ethnographic fieldwork and interviews with cultural elders, ritual practitioners, and local authorities, the study documents how ri’i—a ritual-based regulatory system for bamboo resource management—has been progressively dismantled through the combined pressures of technocratic governance, land commodification, and shifts toward individualism. Empirically, the main drivers identified are state land certification (including Sertifikat Hak Milik, SHM) and village modernization campaigns, which reconfigure communal tenure and everyday governance practices. Once embedded …

Scripture Spotlight: What Was The Role Of The Scapegoat?, Roy Gane

Faculty Publications

No abstract provided.

Effect Of Density Irregularities On Radio Frequency Wave Propagation In Ionospheric Plasmas, Eun-Hwa Kim, Jay Johnson, Syun'ichi Shiraiwa, Nicola Bertelli, Masayuki Ono, Simon Wing

Faculty Publications

No abstract provided.

Navigating Prediabetes In A Foreign Country: A Qualitative Study Of Self-Management Experiences Among Chinese-Speaking Immigrants In Australia, Min Zhang, Kirsten J. Coppell, Johnny Lo, Lisa Whitehead

Research outputs 2022 to 2026

Aim: Chinese-speaking immigrants in Australia have a higher risk of type 2 diabetes and face more barriers to accessing quality healthcare compared to non-culturally and linguistically diverse populations. This study aimed to explore the self-management experiences of Chinese-speaking Australians with self-reported lived experience of prediabetes following immigration. Design: Qualitative study. Methods: Semi-structured interviews were conducted with 10 purposively selected Australian Chinese-speaking immigrants aged over 40 years. Data collection was undertaken in Perth, Western Australia between April and August 2024. Data were analysed using reflexive thematic analysis. Results: Three themes are presented in this paper: (1) An acculturation journey: Reshaping cultural …

Generative Artificial Intelligence (Genai) In Procurement And Supply Chain Management: Applications, Opportunities And Challenges, Vinay Singh, Laurie Hughes, Mousa Ahmed Albashrawi, Il Jeon, Yogesh K. Dwivedi

Research outputs 2022 to 2026

Purpose: This article aims to explore the transformative potential of generative artificial intelligence (GenAI) in procurement and supply chain management (SCM), with a focus on its practical applications, strategic implications and integration challenges. Design/methodology/approach: Adopting a conceptual approach, this article presents the authors’ views and arguments, supported by a review of existing literature and informed by insights from discussions with industry experts. The discussion in this conceptual article is anchored in the supply chain operations reference model. Findings: This research addresses critical questions regarding the practical and strategic impacts of GenAI, emphasizing its ability to simulate scenarios, deliver real-time insights …

Promoting The Concept Healthy Ageing For Use In Gerontological Health And Social Care Policy And Practice, Claire Donnellan

Research outputs 2022 to 2026

Aims: The concept of healthy or successful ageing dates back to the 1960s, where its goal is more realistic in today's ageing society as a result of effective interventions to control and reduce disability and health risks. The aim of this paper is to outline the importance of defining ageing, the semantics and indicators used, and to identify common challenges for health professionals' understanding and application of a healthy ageing approach in their everyday clinical practice. Design and Methods: This discursive paper demonstrates how realistic ageing indicators are for highlighting the variation and impact of challenges associated with ageing. It …

Nation, Nature And Childhood In Five Curricula: Towards Earthly Education, Zsuzsa Millei, Katarzyna Gawlicz, Lucy Hopkins, Camilla Eline Andersen, Danielle Ekman Ladru

Research outputs 2022 to 2026

This article explores the relations between nation, nature and childhood in five early childhood education curricula in the Nordic, post-socialist and settler-colonial states with the focus on the role education plays in the face of the climate crisis. The authors identify three interconnecting themes in which nation, nature and childhood are entangled in these curricula: 1) national nature as an object of learning; 2) nature and home/birth land and Country; and 3) stewardship for national nature. Exploring these themes from the perspective of alternative pedagogies developed to address the child–nature relations during the Anthropocene, the authors argue that these notions …

Embodying Policy Work: An Exploration Of Contexts, Actions And Meanings Towards New Possibilities For Physical Education Teacher Education (Pete), Victoria Evans, David Aldous, Dawn Penney

Research outputs 2022 to 2026

This theoretical paper presents a heuristic framework that is directed towards transformative thinking and practices in Physical Education Teacher Education (PETE). The research focus and direction, embodying policy work, applies and extends Bernstein’s concepts of the pedagogic and corporeal device to offer new directions for inquiry and explore the considerations these raise for PETE professionals and their practices. The paper affirms the importance of policy work in PETE, while recognising a need for more nuanced and critical understandings of the complex interrelationships between contexts and actions, and the potential meanings generated and ascribed to different forms of policy work and …

A Figurational Analysis Of Health And/Or Physical Education Teacher Educators’ Conceptualisations Of Policy, And Their Sociogenesis, Laura Alfrey, Dylan Scanlon, David Aldous, Jenna Lorusso, Kellie Baker, Christopher Clark, Mo Jafar

Research outputs 2022 to 2026

Policy engagement is key to promoting quality physical education yet it has been identified as a ‘grand challenge’ for Health and/or Physical Education (H/PE) internationally. All H/PE professionals, including teacher educators, have a collective responsibility to engage with policy but existing research tells us little about how H/PE teacher educators (H/PETEs) understand and engage with policy. It is important to examine H/PETEs conceptualisations of policy for a few reasons, not least because teacher educators play a crucial role in supporting future generations of teachers who themselves will need to engage with policy as a core feature of their professional lives. …

Investigation Of Causal Relationships Of The Cross-Scale Wave Coupling Through Information Theoretical Approach, Elmer Rivera, J. Johnson, Simon Wing, Eun-Hwa Kim, Khan-Hyuk Kim, Katariina Nykyri

Faculty Publications

No abstract provided.

Comparative Analysis Of Ev-Charging Converters Using Silicon Carbide Mosfets And Silicon Igbt’S, Muhammad A. Kahn

Electrical Engineering Theses

The rapid expansion of electric vehicle (EV) charging infrastructure has increased the demand for efficient and reliable power electronic converters. Semiconductor device selection is critical to system performance, influencing efficiency, power density, and reliability. This thesis presents a comparative analysis of Silicon (Si) Insulated Gate Bipolar Transistors (IGBTs) and Silicon Carbide (SiC) MOSFETs in a representative EV charging converter, with emphasis on electrical performance and thermal behavior under identical operating conditions.

The research employs PLECS (Plexim) and electro-thermal simulation models to accurately characterize device and system interactions. The converter configuration consists of a grid-connected voltage source inverter (VSI) that maintains …

The Manifestation Of Antihaitianismo In Abinader’S Dominican Political Atmosphere, Isabella Alcantara

FCRH Honors Program Theses

In the past decade, Haitian migration has become central to Dominican political discourse. This shift is particularly evident under President Luis Abinader’s administration, which has overseen a sharp increase in restrictive border enforcement and citizenship measures targeting Haitian migrants fleeing escalating humanitarian crises. While existing scholarship on Dominican nationalism highlights the historical role of antihaitianismo in shaping exclusionary state practices, less attention has been paid to how contemporary elite rhetoric reproduces these dynamics in more indirect, coded ways. Drawing on theories of symbolic politics and securitization, this study examines how state discourse constructs Haitian migrants within national narratives. It asks: …

The Long Life Of Illumination: How Medieval Manuscripts Shaped Modern Print Culture, Malena Sullivan

FCRH Honors Program Theses

Design is everywhere in our lives, from product and book layouts to advertisements and the web. Design packages information into visually appealing formats which grab attention and relate an easily understood message. Through fonts, illustrations, patterns, and color, good design does more than just convey information. Rather, it is an art form in itself that has the power to stay within the viewer’s imagination through impactful visuals. The act of designing is a creative process, but also one that often borrows from the past. Before printing was widely adopted in Europe in the fifteenth century, books were written out and …

Dual Targeting Of Amrc12 And Malassezia Globosa Disrupts Myc Liquid Condensates-Driven Nuclear Pore Complex Biogenesis In Neuroblastoma, Anpei Hu, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Shunchen Zhou, Bosen Zhao, Jiaying Qu, Xiaojing Wang, Liduan Zheng, Qiangsong Tong

Faculty, Staff and Students Publications

Rationale: Neuroblastoma (NB) is a predominant extra-cranial malignancy in childhood, while molecular drivers of its progression and effective treatment strategies have yet to be clarified.

Methods: RNA sequencing was performed to identify transcriptional regulators and corresponding target genes. To explore the biological effects and underlying mechanisms of these regulators, a comprehensive methodology was utilized, encompassing chromatin immunoprecipitation, dual-luciferase reporter assay, qRT-PCR, western blot, alongside gene over-expression and silencing techniques, co-immunoprecipitation, and mass spectrometry. The MTT assay, soft agar colony formation, Matrigel invasion, and nude mouse xenograft models were applied to assess oncogenic properties. Patient survival was analyzed using the log-rank …

Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee

Faculty, Staff and Students Publications

The Veterans Health Administration (VHA), the largest employer of nurses in the United States, has more than 120,000 nursing personnel providing care to over 9 million Veterans across diverse settings. Despite nursing's central role in delivering and sustaining care, research on strengthening the nursing workforce and optimizing nursing practice has remained underdeveloped in VHA. To address this gap, VHA's Office of Research and Development, in partnership with the Office of Nursing Services, convened a State of the Art (SOTA) conference in November 2023 focused on nursing. The Nursing SOTA brought together nurses, researchers, operational leaders, and other stakeholders to review …

Assessment Of In-Frame Indel Variants In An Unsolved Cohort Of Inherited Retinal Diseases Using Machine Learning, David E Rauch, Meng Wang, Muhammad Jafar Hussain Hafiz, Daniel C Brock, Yumei Li, Molly Marra, Mark E Pennesi, Paul Yang, Everett Lesley, Irma Lopez, Robert Koenekoop, Edward Ryan Collantes, Joanne Bolinao, Rui Chen

Faculty, Staff and Students Publications

The standard for in silico pathogenicity prediction of in-frame insertions and deletions (indels) is less established compared to other types of variations. We aimed to systematically assess the performance of in silico machine learning (ML) tools on a patient cohort with inherited retinal diseases (IRDs). The performance of four ML tools (CADD, FATHMM-indel, VEST4, and MetaRNN-indel) was compared. Among them, MetaRNN-indel showed the best overall results. MetaRNN-indel was then applied to 1013 unsolved IRD patients, identifying two likely pathogenic causal variants in two unrelated IRD patients by confirming clinical phenotypes. Hence, our findings indicate that reliable prediction of the pathogenicity …

Strategies And Challenges For The Recruitment Of Young Healthy Participants In The Dietary Approaches To Longevity And Health (Dial Health) Pilot Trial, Hannah E Cabre, Courtney M Peterson, Gareth R Dutton, Kimberly L Drews, Stephanie T Broyles, Robert Dubin, Laura Q Rogers, Catherine Champagne, Dennis T Villareal, Daniel S Hsia, Leanne M Redman, Corby K Martin

Faculty, Staff and Students Publications

Background: Understanding the impact of nutrition on human aging requires long-term trials in young, healthy, unmedicated adults. As part of the Dietary Approaches for Longevity and Health (DiAL Health) pilot project, we evaluated strategies for recruiting this population for aging-related dietary intervention studies.

Methods: We analyzed recruitment costs to enroll 70 participants (ages 25-49, BMI 22.0-29.9 kg/m2) across two DiAL Health sites and used NHANES data (2017-March 2020) to estimate the proportion of U.S. adults meeting partial trial eligibility. Additionally, a formative study surveyed 492 U.S. adults (≥18 years) to assess interest in aging-focused dietary trials.

Results: Of 2049 applicants …

Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso

Faculty, Staff and Students Publications

Wastewater-based epidemiology (WBE) is the analysis of wastewater to detect pathogen levels or activity for public health awareness or action. Pioneered in the 1940s, WBE underwent a resurgence during the COVID-19 pandemic, providing important information about number of cases, outbreaks, and seasonal impact. With advancements in detection technologies and growing interest in environmental surveillance, WBE is poised to become a standard practice in public health monitoring. Here, we provide an overview of the current state of the art of pathogen WBE, including methods of molecular detection, analysis of wastewater data, real-world applications and programs, public health interventions, and benefits and …

Lysine Demethylase 4a Is A Centrosome-Associated Protein Required For Centrosome Integrity And Genomic Stability, Pratim Chowdhury, Xiaoli Wang, Richard I Han, Manga Motrapu, Ashley G Boice, Yuya Nakatani, Sofia Vargas-Hernandez, Julia F Love, Claude Chew, Sandra L Grimm, Dereck Mezquita, Frank M Mason, Elisabeth D Martinez, Cristian Coarfa, Cheryl L Walker, Anna-Karin Gustavsson, Ruhee Dere

Faculty, Staff and Students Publications

Centrosomes play a fundamental role in nucleating and organizing microtubules in the cell and are vital for faithful chromosome segregation and maintenance of genomic stability. Loss of structural or functional integrity of centrosomes causes genomic instability and is a driver of oncogenesis. Here we identify lysine demethylase 4A (KDM4A), an epigenetic 'eraser' of chromatin methyl marks, as a centrosome-localized protein, visualized at the nanometer-scale resolution. We additionally uncovered that KDM4A demethylase enzymatic activity is required to maintain centrosome homeostasis and integrity; a previously unknown functionality unlinked to altered expression of genes regulating centrosome number. We find that KDM4A interacts with …

Clinical Factors And Diagnoses Associated With Inappropriate Urine Culture Ordering In Primary Care, Marissa Valentine-King, Barbara W Trautner, Michael A Hansen, Roger Zoorob, Lisa C K Danek, Kenneth Muldrew, Forrest Hudson, Robert L Atmar, Larissa Grigoryan

Faculty, Staff and Students Publications

Objective: Evaluate the prevalence and risk factors for inappropriately ordered urine cultures in primary care.

Design: Cross-sectional study using chart reviews.

Setting: Two primary care, safety-net clinics in Houston, Texas.

Patients: Non-pregnant adults without a urinary catheter who had a urine culture and a primary care visit between 11/2018 and 3/2020.

Methods: We classified patients lacking physician documentation of the following symptoms as having an inappropriately ordered urine culture: dysuria, frequency, urgency, hematuria, fever, chills, costovertebral angle tenderness, nephrolithiasis, and pain (suprapubic, pelvic, or flank). We extracted patient demographics, visit-related diagnostic codes, past medical history, and urine culture results. Diagnostic …

Between Trends And Truths: Tiktok Therapy-Speak And Mental Health, Zoe Stephens

Scripps Senior Theses

The rise of therapy-speak on social media has introduced mental health terminology into everyday discourse among young adults, yet its psychological impacts remain unclear (Chevalier, 2024; Jain et al., 2025). The present study investigated the effects of TikTok videos containing therapy-speak on stigma toward mental illness, mental health awareness, and mental health literacy. Using a between-groups experimental design, 95 U.S. college students aged 18 to 24 were randomly assigned to view either therapy-speak TikTok content or neutral TikTok content. Participants subsequently completed three post-exposure measures: the Mental Health Literacy Scale (MHLS; O’Connor & Casey, 2015), a self-constructed Mental Health Awareness …

End-To-End Development And Experimental Validation Of A 1/10-Scale Autonomous Vehicle, Rikkin Pankaj Panchal

Electrical Engineering Theses

Autonomous vehicle development demands vast resources, making scaled down platforms a critical alternative for solving core algorithmic challenges. The primary contribution of this thesis is the end to end development and validation of a complete real time autonomous driving pipeline deployed on a one tenth scale vehicle. To streamline platform development, an AI assisted annotation framework automates dataset generation, significantly reducing manual labor while improving training data quality. The system perception stack features a reinforcement learning guided online multi camera calibration framework that enables adaptive surround view stitching without the need for offline recalibration. This is paired with robust lane …

Senolytic-Resistant Senescent Cells Have A Distinct Sasp Profile And Functional Impact: The Path To Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K Palmer, Nino Giorgadze, Christina Inman, Nathan Gasek, Ming Xu, Kurt O Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa P G Langhi Prata, Yi Zhu, Renuka Kandhaya-Pillai, Stefan G Tullius, Saranya P Wyles, Rambabu Majji, Hari Krishna Yalamanchili, David B Allison, Tamar Tchkonia, James L Kirkland

Faculty, Staff and Students Publications

The senescent cell (SC) fate is linked to aging, multiple disorders and diseases, and physical dysfunction. Senolytics, agents that selectively eliminate 30%-70% of SCs, act by transiently disabling the senescent cell antiapoptotic pathways (SCAPs), which defend those SCs that are proapoptotic and pro-inflammatory from their own senescence-associated secretory phenotype (SASP). Consistent with this, a JAK/STAT inhibitor, Ruxolitinib, which attenuates the pro-inflammatory SASP of senescent human preadipocytes, caused them to become "senolytic-resistant". Administering senolytics to obese mice selectively decreased the abundance of the subset of SCs that is pro-inflammatory. In cell cultures, the 30%-70% of human senescent preadipocytes or human umbilical …