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Interview With Orca Winner Xiao Cheng Zeng; Unl Chemistry; Computational/Theoretical; Nebraska Ice & Gold Nanocages, Mark Griep, Xiao Cheng Zeng Jun 2026

Interview With Orca Winner Xiao Cheng Zeng; Unl Chemistry; Computational/Theoretical; Nebraska Ice & Gold Nanocages, Mark Griep, Xiao Cheng Zeng

UNL ORCA Interview Series

Xiao Cheng Zeng became a chemistry professor at the University of Nebraska-Lincoln in 1993, quickly rose through the ranks, and was in the department for 29 years. In 2022, he left to become head of the Department of Materials Science and Engineering at the City University of Hong Kong. Xiao was born in Beijing and earned a bachelor’s in physics at the University of Beijing in 1984. Next, he traveled 6800 miles east to Ohio State University in Columbus where he earned his doctorate in condensed matter physics. He followed that up with two postdoctoral experiences, first at the University …


Ultracold Neutron Energy Spectrum And Storage Properties From Magnetically Induced Spin Depolarization, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, D. Bowles, G. L. Caratsch, E. Chanel, W. Chen, P. J. Chiu, C. B. Crawford, V. Czamler, M. Daum, C. B. Doorenbos, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, B. Lauss, T. Lefort, A. Lejuez, R. Li, K. Michielsen, J. Micko, P. Mullan, A. Mullins Jun 2026

Ultracold Neutron Energy Spectrum And Storage Properties From Magnetically Induced Spin Depolarization, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, D. Bowles, G. L. Caratsch, E. Chanel, W. Chen, P. J. Chiu, C. B. Crawford, V. Czamler, M. Daum, C. B. Doorenbos, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, B. Lauss, T. Lefort, A. Lejuez, R. Li, K. Michielsen, J. Micko, P. Mullan, A. Mullins

Physics and Astronomy Faculty Publications

We present a novel method for extracting the energy spectrum of ultracold neutrons from magnetically induced spin depolarization measurements using the n2EDM apparatus. This method is also used to exploit sensitivity to the storage properties of the materials used to trap ultracold neutrons, specifically, whether collisions are specular or diffuse. To do so, we utilize tomat simulation to map storage properties to correlation times of the ultracold neutrons to induced magnetic nonuniformities. We highlight the sensitivity of this new technique by comparing the two different storage chambers of the n2EDM experiment, which host different ultracold neutron energy spectra. This method …


Automated Physical Activity Support For Adults And Youth From Low-Income Communities: Single-Arm Pilot Study., Jordan A. Carlson, Frank T. Materia, Mallory Moon, Suryeon Ryu, Cory Yeager, Chelsea Steel, Kacee Shields, Harpreet Singh Gill, Jannette Berkley-Patton, Delwyn Catley Jun 2026

Automated Physical Activity Support For Adults And Youth From Low-Income Communities: Single-Arm Pilot Study., Jordan A. Carlson, Frank T. Materia, Mallory Moon, Suryeon Ryu, Cory Yeager, Chelsea Steel, Kacee Shields, Harpreet Singh Gill, Jannette Berkley-Patton, Delwyn Catley

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Mobile health (mHealth) interventions are growing in popularity, but less research has focused on low-income families, particularly interventions integrating wearable devices with automated personalized messages.

OBJECTIVE: We tested a preliminary wearable-integrated mHealth intervention with initial personalization elements among adults and youth from low-income urban communities, focusing on feasibility, acceptability, and preliminary evidence of physical activity behavior.

METHODS: Participants were 83 adults and 31 youth recruited through community health events held in low-income urban communities. Using a single-arm pre-post design, participants were enrolled into a 7-week beta-version mHealth intervention that integrated a Garmin activity monitor with automated text messages. Messages …


Relationship Between Sleep And Meal Timing With Glycemia Parameters In Individuals With Obesity Participating In A Randomized Time-Restricted Eating Study., Sirimon Reutrakul, Stacey L. Simon, Qi Wang, Emily N C Manoogian, Satchindananda Panda, Suryeon Ryu, Zan Gao, Caleb Griffiths, Erika Helgeson, Douglas G. Mashek, Niki Oldenburg, Lisa Senye Chow Jun 2026

Relationship Between Sleep And Meal Timing With Glycemia Parameters In Individuals With Obesity Participating In A Randomized Time-Restricted Eating Study., Sirimon Reutrakul, Stacey L. Simon, Qi Wang, Emily N C Manoogian, Satchindananda Panda, Suryeon Ryu, Zan Gao, Caleb Griffiths, Erika Helgeson, Douglas G. Mashek, Niki Oldenburg, Lisa Senye Chow

Manuscripts, Articles, Book Chapters and Other Papers

Background/Objectives: Circadian misalignment, including mistimed sleep or eating, is associated with altered glucose metabolism. The importance of eating window timing for time-restricted eating (TRE) is increasingly recognized. This secondary analysis examined associations between meal to sleep timing intervals and glycemic parameters in individuals with obesity across three dietary interventions [TRE, CR: caloric restriction, and UE: unrestricted eating]. Methods: Participants aged 18-65 years with obesity were randomized to a 12-week intervention: TRE (8 h eating window), CR (15% reduction in daily caloric intake), or UE (usual eating habits). CGM and actigraphy were assessed over two weeks at baseline and end-intervention. Mixed …


Growth In Early Infancy Drives Optimal Brain Functional Connectivity Which Predicts Cognitive Flexibility In Later Childhood, Chiara Bulgarelli, Anna Blasi, Samantha Mccann, Bosiljka Milosavljevic, Giulia Ghillia, Ebrima Mbye, Ebou Touray, Tijan Fadera, Lena Acolatse, Sophie E Moore, Sarah Lloyd-Fox, Clare E Elwell, Adam T Eggebrecht, Bright Study Team Jun 2026

Growth In Early Infancy Drives Optimal Brain Functional Connectivity Which Predicts Cognitive Flexibility In Later Childhood, Chiara Bulgarelli, Anna Blasi, Samantha Mccann, Bosiljka Milosavljevic, Giulia Ghillia, Ebrima Mbye, Ebou Touray, Tijan Fadera, Lena Acolatse, Sophie E Moore, Sarah Lloyd-Fox, Clare E Elwell, Adam T Eggebrecht, Bright Study Team

2020-Current year OA Pubs

Functional brain network organisation, measured by functional connectivity (FC), reflects key neurodevelopmental processes for healthy development. Early exposure to adversity, for example undernutrition, affects neurodevelopment, observable via disrupted FC, and leads to poorer outcomes from preschool age onwards. We assessed longitudinally the impact of early growth trajectories on developmental FC in a rural Gambian population from age 5-24 months. To investigate how these early trajectories relate to later childhood outcomes, we assessed cognitive flexibility at 3-5 years. We observed that early physical growth before the fifth month of life drove optimal developmental trajectories of FC that in turn predicted cognitive …


Scaffolded Reflection And Research Assignment For Sociology 101, Sara Martucci Jun 2026

Scaffolded Reflection And Research Assignment For Sociology 101, Sara Martucci

Open Educational Resources

Dr. Sara Martucci created these assignments as part of a funded project focused on converting more sections of high-enrollment foundational courses to use Open Educational Resources and Pedagogy.


Analysis Of The Relationship Between The Timing Of Foot Pressure Mechanics And Force At The Moment Of Leaping And The Accuracy Of Heading Of Young Football Players, Widad Kadhim Majeed, Huda Shihab Jari, Mariam Abduljabbar Khudhair, Félix Arbinaga Ibarzábal Jun 2026

Analysis Of The Relationship Between The Timing Of Foot Pressure Mechanics And Force At The Moment Of Leaping And The Accuracy Of Heading Of Young Football Players, Widad Kadhim Majeed, Huda Shihab Jari, Mariam Abduljabbar Khudhair, Félix Arbinaga Ibarzábal

Modern Sport

Football is a dynamic sport that requires both physical and technical skill because it is played within a specific timeframe and in a large space; physical ability is inseparable from technical proficiency among a match. This research aims to analyze the relationship between the timing of foot pressure, force generated at take-off, and heading accuracy in youth football players. A descriptive correlational approach was used on a sample of (8) players. Data were collected using a Foot Scan platform andvideo analysis. The results it was significant correlations between biomechanical variables and heading accuracy. The highest recorded correlation reached (R = …


Iris - Integrated Reef Information System, Colin Friedel, Zach Henderson, Cooper Mccarthy, Elias Pedroza, Thatcher Steele-Maley Jun 2026

Iris - Integrated Reef Information System, Colin Friedel, Zach Henderson, Cooper Mccarthy, Elias Pedroza, Thatcher Steele-Maley

Interdisciplinary Design Senior Theses

Our project provides an independent addition to the existing REEF Sensor Network, which has been created by the Santa Clara University Robotics Systems Lab and is planned to be deployed in the Palos Verdes Reef. Our system enables wireless transmission of data from the submerged sensor network to the scientist on land by designing and implementing a submersible winch mechanism to automatically raise and lower a buoy from the ocean floor to the surface, and cellular connectivity to wirelessly transmit collected data from the buoy to shore. After the data is transmitted, the buoy is lowered back to the sea …


Extraction Of Key Themes In Online Health Discourse Using Unsupervised Learning And Large Language Models, Miranda G. Scully Jun 2026

Extraction Of Key Themes In Online Health Discourse Using Unsupervised Learning And Large Language Models, Miranda G. Scully

Computer Science Senior Theses

Health online discussion boards are a modern platform that allow patients to interact with each other and the healthcare system as a whole, making them valuable sources of information for clinicians seeking to better anticipate treatment experiences and barriers. This study focuses on one such community, r/suboxone, a subreddit where patients using Suboxone share their experiences and ask questions. Our analysis is motivated by previous work that proposes event-based classification systems for such posts which buckets posts from r/suboxone into one or more of five high-level labels (Access Logistics, Co-Occurring Drug Usage, Medication for Opioid Use Disorder Administration, Psychophysical Effects, …


Rehabvr: A Virtual Reality System For Upper-Body Orthopaedic Physical Therapy Rehabilitation, Winnie Brenda Wanjiru Waiya Jun 2026

Rehabvr: A Virtual Reality System For Upper-Body Orthopaedic Physical Therapy Rehabilitation, Winnie Brenda Wanjiru Waiya

Computer Science Senior Theses

Physical therapy is a central component of rehabilitation for musculoskeletal conditions, yet adherence to prescribed treatment remains persistently poor. Jack et al. identified pain, boredom, and insufficient feedback as key barriers to treatment adherence in physiotherapy outpatient settings,¹ and Rucinski et al. confirmed that non-adherence rates in orthopaedic populations remain between 50 and 70%, with patients who disengage facing elevated risk of reoperation, progressive functional decline, and poor clinical outcomes.² According to the World Health Organization, approximately 1.71 billion people globally live with musculoskeletal conditions,³ with shoulder pain specifically carrying a community prevalence ranging from 0.67 to 55.2% worldwide and …


Colonial To Neoliberal Governmentality In Monument Governance: Shifting Positionalities Of The Monument Adjacent Communities In India, Ujal Kumar Mookherjee, Shreyasi Bhattacharya Jun 2026

Colonial To Neoliberal Governmentality In Monument Governance: Shifting Positionalities Of The Monument Adjacent Communities In India, Ujal Kumar Mookherjee, Shreyasi Bhattacharya

Socio-Legal Review

Organised monument governance in India began during the colonial rule. The colonial governance enterprise was bureaucratic and worked through stringent laws which often came down heavily on the monument-adjacent communities. The totalising nature of Indian colonial governmentality fractured the local community, disabling their engagement with the State either as civil society, as individuals or as social groups, while on the other hand enabling such engagement through a “community” constructed on religious lines. Colonial continuities in monument governance meant that a roughly similar position continued in the post-colony. On the international plane, however, there has been a discursive shift in valorisation …


Implementation Of A Mixed Precision Iterative Solver On An Amd Apu, Saeyeon Kim, Henrik Evers Jun 2026

Implementation Of A Mixed Precision Iterative Solver On An Amd Apu, Saeyeon Kim, Henrik Evers

Computer Science and Engineering Senior Theses

Solving systems of linear equations is a core operation in high-performance computing and many scientific and engineering applications. One of the most widely used direct methods for solving such systems is LU factorization. Mixed-precision methods accelerate these solvers by using low-precision LU factorization with iterative refinement, improving performance and energy efficiency while preserving high numerical accuracy. AMD Accelerated Processing Units (APUs), which integrate CPU and NPU resources, provide an opportunity to explore this approach on emerging heterogeneous architectures. However, effective NPU utilization remains challenging due to workload partitioning, buffer management, data-movement overhead, and software tooling limitations.

This project implements a …


The Use Of Surveys In Soliciting Patron Feedback: Effective Strategies For Creating, Promoting, And Applying Them, David J. Fuller Jun 2026

The Use Of Surveys In Soliciting Patron Feedback: Effective Strategies For Creating, Promoting, And Applying Them, David J. Fuller

The Christian Librarian

This literature review examines recent sources that explore ways to optimize the helpfulness of surveys in different information organization management contexts. In the landscape of the scholarly literature on using surveys in information organizations, three significant sub-topics for discussion emerge: strategies for incentivizing participation and completion, using surveys in combination with other assessment measures, and formulating action steps from survey results. These three sub-topics are discussed with a focus on common themes, contradictions, and gaps in existing research.


Thermovision 3d, Daniel Louie, Iker Mendiburu Perez, Kieran Greeley Jun 2026

Thermovision 3d, Daniel Louie, Iker Mendiburu Perez, Kieran Greeley

Interdisciplinary Design Senior Theses

This project presents the development of a three-dimensional thermal mapping system designed to identify energy inefficiencies in buildings. By integrating visible-light imaging with thermal sensing, the system generates detailed 3D models that visualize both structural features and heat distribution. Using photogrammetry techniques, overlapping images are processed to reconstruct building geometry, while thermal data is mapped onto the model to highlight areas of potential heat loss such as insulation gaps, windows, and structural joints.

The system combines hardware and software components, including a dual-camera setup and a custom visualization pipeline, to produce both qualitative and quantitative outputs. Users are able to …


A Protestant Response To The Pope’S Magnifica Humanitas On Ai, Derek Schuurman Jun 2026

A Protestant Response To The Pope’S Magnifica Humanitas On Ai, Derek Schuurman

University Faculty Publications and Creative Works

Pope Leo XIV released his first papal encyclical, Magnifica Humanitas, on May 25, a roughly 42,000-word document outlining a Catholic response to recent developments in AI. I had been eagerly anticipating this encyclical and spent much of the release day poring over the text. While there have been other Christian efforts to release statements about AI, this is the first comprehensive statement from the Catholic Church. What follows is a summary of the document, followed by my own response.


Does A Common Threat Unite?: Alliance Formation In East Asia Under Chinese Pressure, Sean G. Mcclellan Jun 2026

Does A Common Threat Unite?: Alliance Formation In East Asia Under Chinese Pressure, Sean G. Mcclellan

Honors Theses

The study explores whether a shared geopolitical threat fosters alliance formation among East Asian nations, focusing on Taiwan, Japan, and South Korea in the context of increasing Chinese influence. Integrating insights from international relations theory and social psychology—particularly Realistic Conflict Theory and the out-group unifying effect—the research evaluates whether perceived Chinese aggression corresponds with increased positive sentiment toward the United States. Utilizing data from the Asian Barometer Survey, linear regression analysis is conducted to assess how perceptions of Chinese and U.S. influence, democratic values, and political affiliation shape public attitudes. Results show that while negative views of Chinese and U.S. …


Frontal Release Signs And Future Decline In Research Participants With Intact Cognition, Lauren G. Bojarski, Gregory A. Jicha, Elif Pinar Coskun, Frederick A. Schmitt, Linda Van Eldik, Erin L. Abner Jun 2026

Frontal Release Signs And Future Decline In Research Participants With Intact Cognition, Lauren G. Bojarski, Gregory A. Jicha, Elif Pinar Coskun, Frederick A. Schmitt, Linda Van Eldik, Erin L. Abner

Neurology Faculty Publications

Importance Frontal release signs (FRS) are primitive reflexes that regress with brain maturation and reappear in the setting of brain injury or neurodegeneration. Despite their association with dementia, the prognostic utility of this finding in the setting of early cognitive decline and preclinical disease is poorly understood. Objective To evaluate the association of FRS with future cognitive decline in research participants. Design, Setting, and Participants This cohort study examined the presence of FRS (from 2005-2024) among research cohort participants with intact cognition or mild impairment at study baseline. The study used single-center data collection of longitudinal research cohort data through …


Acceptance Of Shared Autonomous Vehicles: Exploring The Attitudes And Perspectives Of Older Adults, Sara Sohaee Urbina Jun 2026

Acceptance Of Shared Autonomous Vehicles: Exploring The Attitudes And Perspectives Of Older Adults, Sara Sohaee Urbina

Dissertations and Theses

The fast development of autonomous vehicle systems will create major changes in how people move around. Previous research shows that these technologies can benefit older people who struggle with mobility, safety and access to transportation. Shared Autonomous Vehicles (SAVs) enable older people to achieve self-reliance while obtaining essential services which enhance their quality of living. The successful deployment of SAVs requires users to accept this new technology which they must also be willing to use. This research study investigates which elements affect older adults to adopt SAVs by using an extended Technology Acceptance Model (TAM) framework.

The research design of …


Foundations' Deep, Emily Williams, Morgan Williams Jun 2026

Foundations' Deep, Emily Williams, Morgan Williams

University Honors Theses

Most historic buildings do not survive as they were built, yet preservation frameworks still tend to evaluate them as if they did.

Foundations' Deep begins with a structure located in Helena, Montana 59602, a building that sits uneasily within the categories it has been asked to meet. Built in the early twentieth century, it has persisted through alteration, abandonment, and use. What remains is not a stable artifact but a record of accumulated decisions, some careful and many indifferent, now embedded in the fabric of the building itself.

The thesis grows from this condition and from the limits of the …


Office Discipline Referral Narratives, Context, And Categorization, Deanna M. Bush Jun 2026

Office Discipline Referral Narratives, Context, And Categorization, Deanna M. Bush

Education Dissertations

This two-part qualitative study examined the experiences of students with disabilities (SWD) in the middle school discipline. Phase one was a qualitative document analysis study that examined school discipline for SWD through the lens of Critical Disability Theory (CDT), Multi-Tiered Systems of Support (MTSS), Constructivist Learning Theory, and the Vulnerable Decision Point model (VDP) in a midsize suburban district in Washington state. The study explored alignment of ODR teacher-written narratives with behavioral categories assigned to the ODR at the time of issue to determine variance based on behavior category or student disability status. Phase two a semi-structured interview (shown on …


Chromatin Insulators Homie And Nhomie Can Interact With Distant Copies Either Together Or Separately, With Distinct Outcomes For Enhancer-Promoter Interactions, Miki Fujioka, Wenfan Ke, Paul Schedl, James B. Jaynes Jun 2026

Chromatin Insulators Homie And Nhomie Can Interact With Distant Copies Either Together Or Separately, With Distinct Outcomes For Enhancer-Promoter Interactions, Miki Fujioka, Wenfan Ke, Paul Schedl, James B. Jaynes

Department of Biochemistry and Molecular Biology Faculty Papers

Chromatin insulators, a.k.a. boundary elements, separate regions of the chromosome with distinct chromatin characteristics, including distinct histone modifications. This activity affects gene expression by allowing chromatin domains to be stably regulated and maintained. Insulators also block enhancer-promoter interactions and, somewhat paradoxically, facilitate other interactions, particularly when they stitch together distant regions of the chromosome by pairing with specific partners. Here we explore how long-range interactions facilitated by insulator pairing are affected by the presence of two potentially competing partners. Our results show that when two partners are present, they can reduce each other's effects on distant gene expression, suggesting that …


Phasing Out A Way Of Life: How Decarbonization Affects Coal Dependent Communities, Alex Loeb Jun 2026

Phasing Out A Way Of Life: How Decarbonization Affects Coal Dependent Communities, Alex Loeb

Duke Environmental Law & Policy Forum

As member states seek to comply with European Union industry rationalization directives that will force mines that cannot compete with free-market prices without subsidies to close, domestic governments across Europe will face competing pressure from civil society. Many traditional European mining communities are dependent on the coal industry and will resist the phase out of its position in the European energy mix. In Asturias, Spain, the phase out of non-competitive coal mines has had devastating impacts on former mining towns, as they struggle to transition to a coal-free economy. After phasing out coal, Asturias has struggled with unemployment and significant …


Statistical Methods In Research, Horahenage Dixon Vimalajeewa Jun 2026

Statistical Methods In Research, Horahenage Dixon Vimalajeewa

UNL Faculty Course Portfolios

This course portfolio documents the design, delivery, assessment, student-learning evidence, and reflective evaluation of STAT 801A-700: Statistical Methods in Research, an online asynchronous service course designed to introduce students from diverse disciplinary backgrounds to foundational statistical reasoning and applied data analysis. The course is a non-calculus-based introduction to statistical methods used to answer research questions, with emphasis on collecting, organizing, describing, analyzing, and drawing conclusions from data. The course also emphasizes applications relevant to biology, agriculture, and other research-oriented fields. This is an online distance course aimed to develop students’ understanding of basic probability and statistical concepts, recognize the importance …


Course Portfolio: Elements Of Physics Phys 151, Evan A. Rich Jun 2026

Course Portfolio: Elements Of Physics Phys 151, Evan A. Rich

UNL Faculty Course Portfolios

This course portfolio documents the instructional design, teaching methods, and ongoing assessment efforts for PHYS 151: Elements of Physics, an algebra-based introductory physics course at the University of Nebraska-Lincoln. The course serves a broad undergraduate population, including architecture, construction management, and life science majors. The portfolio describes the teaching framework that integrates pre-lecture video preparation, active in-class engagement through iClicker questions, and collaborative weekly recitation sections, all unified around a structured six-step problem-solving approach. A central concern of the course is building students’ self-efficacy in physics, particularly among those with math anxiety or limited preparation. Two assessments are reported: a …


‘Wala Kaming Alam Sa Stroke Care’ (We Don’T Know Anything About Stroke Care): Experiences Of Care Providers Delivering Stroke Rehabilitation Care In The Philippines, Fiona Leggat, Sarah Ann Buckingham, Aira Patrice Rueda Ong, Bridie Kent, Nena Marie Santos, Annah Teves, Vergil Boac, Paula Melizza Valera, Elda Anota, Maria Mercedes Barba, Myrna Estrada, Neil Bryan Pita, Alyssa Dar Juan, Lorraine Faeldon, Fiona Jones Jun 2026

‘Wala Kaming Alam Sa Stroke Care’ (We Don’T Know Anything About Stroke Care): Experiences Of Care Providers Delivering Stroke Rehabilitation Care In The Philippines, Fiona Leggat, Sarah Ann Buckingham, Aira Patrice Rueda Ong, Bridie Kent, Nena Marie Santos, Annah Teves, Vergil Boac, Paula Melizza Valera, Elda Anota, Maria Mercedes Barba, Myrna Estrada, Neil Bryan Pita, Alyssa Dar Juan, Lorraine Faeldon, Fiona Jones

School of Nursing and Midwifery

BackgroundIn the Philippines, rising stroke prevalence and healthcare inequalities present a concerning outlook. While acute stroke care is prioritised, rehabilitation remains undervalued. The experiences of healthcare providers who deliver stroke support are also under-researched.Objective(s)Our study aimed to explore the experiences and needs of care providers across multiple regions of the Philippines to inform the development of stroke support initiatives and programmes.MethodsForming part of the Tulong, Ugnayan ng Lingap At gabaY (TULAY) project, a qualitative descriptive design involving semi-structured interviews was used. Care providers with professional or voluntary community healthcare service delivery roles were recruited. Data were analysed using reflexive thematic …


Disease-Causing Mfn2 Mutants Impair Mitochondrial Fission Dynamics By Distinct Drp1 Dysregulation, Daniel Lagos, Pamela R. De Santiago, Nicolás Pérez-Bravo, Benjamín Cartes-Saavedra, Josefa Vial-Brizzi, Diego Troncoso-Chandía, Oliver Podmanicky, Rita Horvath, Verónica Eisner Jun 2026

Disease-Causing Mfn2 Mutants Impair Mitochondrial Fission Dynamics By Distinct Drp1 Dysregulation, Daniel Lagos, Pamela R. De Santiago, Nicolás Pérez-Bravo, Benjamín Cartes-Saavedra, Josefa Vial-Brizzi, Diego Troncoso-Chandía, Oliver Podmanicky, Rita Horvath, Verónica Eisner

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Mitochondria undergo fusion and fission. While DRP1 regulates fission, fusion is controlled by OPA1, MFN1, and MFN2. The balance between these processes and the crosstalk between machineries remains poorly understood. MFN2 mutations cause Charcot-Marie-Tooth disease type 2 A (CMT2A), affecting mitochondrial fusion and morphology. However, their role in fission is unclear. Using skin fibroblasts from CMT2A patients (L248H and M376V MFN2 mutations) and wild-type mouse embryonic fibroblasts expressing these variants, we studied how MFN2 mutations impact mitochondrial dynamics beyond fusion. We analyzed mitochondrial morphology and dynamics by live-cell confocal microscopy and tested fusion/fission protein levels, oxygen consumption rate (OCR), extracellular …


Chatgpt, Where Should I Go? A Qualitative Exploration Of How Large Language Models Are Experienced As Support For Travel Planning, Mohammad Amin Kuhail, Asbjørn Følstad, Saifeddin Alimamy Jun 2026

Chatgpt, Where Should I Go? A Qualitative Exploration Of How Large Language Models Are Experienced As Support For Travel Planning, Mohammad Amin Kuhail, Asbjørn Følstad, Saifeddin Alimamy

All Works

Large language models (LLMs) are increasingly used for travel planning. Yet, little is known about how travellers experience and interact with such language models. This qualitative study explores how users employ LLMs to plan trips, drawing on the hedonic/pragmatic model of user experience to examine functional and affective dimensions. We collected data from 104 participants with prior experience using LLMs for travel advice through open-ended questionnaire responses. Thematic analysis revealed three key insights: (1) users value the pragmatic benefits of LLMs, such as efficiency, clarity, and confidence in decision-making, while also appreciating hedonic qualities, including inspiration, enjoyment, and authenticity; (2) …


A Machine Learning Framework For Contractor Scope Matching Using Profile Characteristics And Work Package Vector Similarity, Pedro Fonseca, Sergei Chuprov Jun 2026

A Machine Learning Framework For Contractor Scope Matching Using Profile Characteristics And Work Package Vector Similarity, Pedro Fonseca, Sergei Chuprov

Computer Science Faculty Publications

This paper presents a machine learning-based framework for predicting contractor performance in the construction industry by integrating contractor profile information with work package characteristics. The proposed approach addresses procurement challenges arising from the misalignment between contractor expertise and assigned scopes, a key contributor to cost overruns and schedule delays. Unlike existing models that rely on aggregated project-level indicators, the framework enables scope-aware performance prediction by leveraging the Work Breakdown Structure (WBS) to capture similarity among work packages. Contractor profiles are encoded using historical performance data, while WBS elements are vectorized to quantify scope similarity and contextualize predictions. Experimental results demonstrate …


Exploring Strategies For Reducing Employee Turnover In Healthcare Facilities, Khaddy Jammeh Jun 2026

Exploring Strategies For Reducing Employee Turnover In Healthcare Facilities, Khaddy Jammeh

Walden Dissertations and Doctoral Studies

No abstract provided.


Synthesis And Characterization Of Synergistic Bioactive– Organometallic Condensation Polymers, Francesca Isabel Mosca Jun 2026

Synthesis And Characterization Of Synergistic Bioactive– Organometallic Condensation Polymers, Francesca Isabel Mosca

Electronic Theses and Dissertations 2020 - Present

This research focuses on the synthesis and structural characterization of polymers with anticipated anticancer and antiviral properties by combining metal-containing Lewis acids, organotin dichlorides (R2SnCl2), Group 4 metallocene dichlorides (Cp2TiCl2, Cp2ZrCl2 and Cp2HfCl2), and triphenyl Group 15 metal dichlorides (Ph3AsCl2, Ph3SbCl2 and Ph3BiCl2), with biologically active Lewis bases, lamivudine, a synthetic nucleoside, and camphoric acid, a dicarboxylic acid, to achieve synergistic effect.

Five classes of polymers were synthesized using interfacial polymerization: lamivudine and organotin dichlorides, lamivudine and Group 4 metallocene dichlorides, camphoric acid and triphenyl Group 15 metal dichlorides, camphoric acid and organotin dichlorides, and camphoric acid and Group 4 …