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Edisson Barros Anguisaca V. Attorney General United States Of America

2024 Decisions

Agency

27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C.Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P. Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu

Division of Basic Science Faculty Publications

Oxysterols are metabolites of cholesterol that regulate cholesterol homeostasis. Among these, the most abundant oxysterol is 27-hydroxycholesterol (27HC), which can cross the blood-brain barrier. Because 27HC functions as an endogenous selective estrogen receptor modulator, we hypothesize that 27HC binds to the estrogen receptor α (ERα) in the brain to regulate energy balance. Supporting this view, we found that delivering 27HC to the brain reduced food intake and activated proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (POMCARH) in an ERα-dependent manner. In addition, we observed that inhibiting brain ERα, deleting ERα in POMC neurons, or chemogenetic inhibition of …

An International Multidisciplinary Consensus On Pediatric Metabolic Dysfunction-Associated Fatty Liver Disease, Le Zhang, Mortada El-Shabrawi, Louise A. Baur, Christopher D. Byrne, Giovanni Targher, Mohit Kehar, Gilda Porta, Way Seah Lee, Sander Lefere, Serap Turan, Anna Alisi, Ram Weiss, Maria Felicia Faienza, Ambika Ashraf, Shikha S. Sundaram, Anshu Srivastava, Ruth De Bruyne, Yunkoo Kang, Flora Bacopoulou, Yong Hai Zhou, Andy Darma, Monica Lupsor-Platon, Masahide Hamaguchi, Anoop Misra, Nahum Méndez-Sánchez, Nicholas Beng Hui Ng, Claude Marcus, Amanda E. Staiano, Nadia Waheed, Saleh A. Alqahtani, Cosimo Giannini, Ponsiano Ocama, Mindie H. Nguyen, Maria Teresa Arias-Loste

Population and Public Health Science Faculty Publications

Background: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in children and adolescents, particularly those with obesity. NAFLD is considered a hepatic manifestation of the metabolic syndrome due to its close associations with abdominal obesity, insulin resistance, and atherogenic dyslipidemia. Experts have proposed an alternative terminology, metabolic dysfunction-associated fatty liver disease (MAFLD), to better reflect its pathophysiology. This study aimed to develop consensus statements and recommendations for pediatric MAFLD through collaboration among international experts. Methods: A group of 65 experts from 35 countries and six continents, including pediatricians, hepatologists, and endocrinologists, participated in a consensus development process. The process encompassed …

Conditional Approval Letter For The 2024 Butte Priority Soils (Bpsou) Residential Metals Abatement Program (Rmap) – Quality Assurance Project Plan (Qapp) Annual Update (Non-Residential Parcels And Residential Daycares) (Dated July 1, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

East African Refugee Women Seeking Health Care After Government Assistance Ends, Sylivia Chelimo

Walden Dissertations and Doctoral Studies

East African refugee women arrive as a vulnerable population in their host country. Before coming to the United States, refugee women may have experienced varying levels of trauma due to civil wars, genocide, sexual assault, deaths of loved ones, terrorist attacks, being taken hostage, and torture in their home country. The purpose of this generic qualitative study was to explore the experiences of refugee women from East African countries seeking health care in the Central United States when government assistance ends. The framework of the behavioral model of health was the guide for examining the experiences of the participant refugee …

School Counselors’ Perceptions And Descriptions Of Their Career Counseling Efforts For Non-Honor Roll Students In Career Management, Sherlette C. Burkhalter

Walden Dissertations and Doctoral Studies

High-quality career counseling is freely available at U.S. high schools. However, many students choose not to participate in career planning programs, despite being assigned to a school counselor for guidance. There is a projected increase in demand for school counselors; however, there needs to be more literature regarding whether high school students are taking advantage of career planning and how counselors cope with and manage their role in implementing career counseling programs. The purpose of this study was to explore school counselors’ perceptions and descriptions of their career counseling efforts for non-honor roll students in career management. The theoretical framework …

The Impact Of Liberia’S Post-War Public Housing Policy On Homelessness, Bofor Rahim Toh, Ii

Walden Dissertations and Doctoral Studies

There is an inadequacy in strategies to address homeless and vulnerable youth “Zogos” in post-war Liberia. Homelessness among youth is a severe problem in post-war Liberia, with many sleeping in Palm Groove Cemetery and other informal housing settings in Monrovia and other parts of the country. This qualitative study explored post-war Liberia’s public housing program policy roles that professional competency and human capacity play in effectively mitigating homelessness of youth in Monrovia. Glasser’s choice theory was the theoretical framework used for this study. The research question explored how human capacity, selection eligibility, and professional competency at the National Housing Authority …

Experiences Of Black Males With Generalized Anxiety Disorder During The Covid-19 Pandemic, Cynthia Lynn Williams

Walden Dissertations and Doctoral Studies

This qualitative research dissertation involved exploring the intersection of race, gender, and mental health via lived experiences of Black males who were diagnosed with generalized anxiety disorder during the COVID-19 pandemic to provide a comprehensive understanding of how the unique sociocultural context of the pandemic influenced their experiences with anxiety. Using a qualitative Interpretive Phenomenological Analysis research design and semi-structured interviews with a diverse sample of seven Black males living in various regions of the United States the interviews involved their personal experiences, coping mechanisms, and perceptions of societal and systemic factors that affected their mental health during the pandemic. …

Carbonate And Organic Proxies And The Impacts Of Climate On Lake Systems: Paleoclimate Interpretations From Lake Chalco, Mexico, Aria Holmes

Earth and Planetary Sciences ETDs

This project incorporates several lines of evidence to better understand the climate at Lake Chalco. Chapter 1 utilizes oxygen isotopes from carbonates and show that the Inter Tropical Convergence Zone varies on primarily glacial and millennial timescales; precession is not observed. These data indicate glacials periods were shallower and interglacials were wetter periods at Lake Chalco. Chapter 2 studies carbon, nitrogen, C/N, and TOC proxies and finds that the lake conditions during the glacials and interglacials are primarily a mixed algal-macrophyte-terrestrial organic matter. Deviations show that the lake during the interglacials had more algal organic matter- reflecting influxes of nutrients …

Domestic Violence Primary Prevention: Evidence From The Past Decade, Ingrid Johnson

AJiC Fact Sheets

This fact sheet summarizes findings from 16 meta-analyses synthesizing the results of evaluations of primary domestic violence prevention interventions between 2014 and 2024. Primary prevention includes policies or programs that stop the onset of crime perpetration and/or victimization. Domestic violence includes sexual violence, stalking, physical violence, psychological aggression, and/or control of reproductive or sexual health by spouses, boy or girlfriends, dating partners, or hook up partners. Findings show a preventative effect amongst youth and community-based adults, while no preventative effect was seen in college students.

Tectonic Geomorphology Of The South-Eastern Section Of The Burdur-Fethiye Shear Zone, Western Taurides: Morphotectonic Framework Of The Eşen Basin, İrem Eli̇tez, Cenk Yaltirak

Turkish Journal of Earth Sciences

The Eşen Basin is a transtensional basin located in the south-eastern section of the Burdur-Fethiye Shear Zone and includes a part of the Western Taurides to the east. This tectonically complex area is bounded by the back-arc region of the Hellenic Arc, the offshore Anaximander Mountains, the offshore Rhodes and Finike basins, the extensional Western Anatolian region, and the compressional regions of the Western Taurides. In this study, in order to characterise the recent tectonic activity of the Eşen Basin, 101 drainage basins and 41 mountain fronts were analysed in terms of the longitudinal river profiles and the application of …

Eocene Magmatism Related To Postcollisional Extension In The Eastern Pontides (Ne Türkiye): 40ar-39ar Geochronology, Geochemistry, And Whole-Rock Sr-Nd-Pb-Hf Isotopes, Emre Aydinçakir, Cem Yücel, Abdullah Kaygusuz, Özgür Bi̇li̇ci̇, Si̇nan Yilmazer, Gilles Ruffet

Turkish Journal of Earth Sciences

The mineral chemistry, whole-rock geochemistry, 40Ar / 39Ar dating and Sr-Nd-Pb-Hf isotopes of the Eocene Narman (Erzurum) Volcanic rocks in the southeast of the Eastern Pontides Orogenic Belt (EPOB, NE Türkiye) were investigated. The Narman Volcanites consist of basaltic dyke, basaltic lava, and basaltic volcanic breccia facies. Volcanites contain plagioclase (An34-80), clinopyroxene (Wo38-47En41-50Fs5-18), and olivine (Fo68-90) as phenocrystals with magnetite/titanomagnetite microphenocrysts. New 40Ar-39Ar ages suggest that these volcanic rocks erupted between 44.5 ± 0.1 and 43.4 ± 0.1 Ma, within the Middle Eocene (Lutetian). Narman Volcanites have calc-alkaline character, with medium-high K content. Volcanites are enriched in large ion lithophile …

Evaluation Of Gis-Based Spatial Interpolation Methods For Groundwater Level: A Case Study Of Türkiye, Ni̇lüfer Ti̇rol Kirçi̇çek, Alper Baba, Ayhan Koçbay, Murat Mert Toklu

Turkish Journal of Earth Sciences

Groundwater is a valuable and universally distributed resource on Earth. Understanding the spatial and temporal dynamics of groundwater is of utmost importance for effective management. Normally, groundwater levels are recorded at arbitrary points, but groundwater modeling requires interpolating the measured values at specific grid nodes. The aim of this study was to identify and evaluate the geographical variations of groundwater levels in Türkiye using three geostatistical interpolation techniques. Data from 355 groundwater wells from 1970 to 2019 were used for this purpose. In addition, an investigation of changes in annual average temperature and precipitation was conducted for two different time …

Facies Architecture And Depositional Evolution Of The Middle Eocene Mass Flow-Dominated Fan Delta Complex In The Multifeeder Areas: Elazığ Marine Basin (Eastern Türkiye), Onur Alkaç

Turkish Journal of Earth Sciences

The mass flow-dominated fan delta complex is developed by the rapid deposition of coarse-grained materials in front of uplifted areas under the influence active tectonism. This is important for providing clues about the first opening stages of marine basins. The study aims to shed light on the fact that mass flow-dominated fan delta complexes play an active role in determining the characterization of tectonism controlling basin opening. In the study area, mass flow-dominated deposits of the Deliktaş Fan Delta Complex (DFDC) represent the first deposits of the southern part of the Middle Eocene Elazığ Marine Basin, whose development is controlled …

Membrane Hinges For Deployable Systems, C. Mitchel Skinner

Theses and Dissertations

Origami-inspired and deployable technology has become increasingly common in a variety of applications including satellite and antenna designs for space applications. The drive to utilize ultra-thin materials in the design of these deployable space structures has led to the development of membrane hinges. Membrane hinges show promise as an effective surrogate fold because of their potential advantages including requiring minimal volume and mass, allowing for small bending radii, and functioning without lubricant. Two challenges associated with membrane hinges include reliability after repeated cyclic loading and predictability of a large deployable with radially-unconstrained membrane hinges. The research presented includes the cyclic …

Development And Initial Validation Of The Musical Discrimination And Styles Task: Measuring Children And Adolescent Music Aptitude And Achievement, Dawn R. Mitchell White

USF Tampa Graduate Theses and Dissertations

This dissertation had two purposes: 1) to create and document the development of a new music achievement test entitled the Musical Discrimination and Styles Task (MDAST), and 2) to describe the strength of the evidence supporting the validity and reliability of this new developmentally appropriate music aptitude and achievement instrument. I created a theoretical framework based on 1) the cognitive theory of child development of Jean Piaget, 2) the phase model of artistic development by David Hargreaves, and 3) the theoretical models of music discrimination, audiation, and music achievement by Edwin Gordon. The MDAST’s design assessed students’ abilities to evaluate …

Development Of Peptidomimetics Based On Γ-Aapeptide Molecular Scaffolds To Modulate Amyloid Peptide Aggregation, Heng Liu

USF Tampa Graduate Theses and Dissertations

Many proteins contain fragments that become structured upon binding to specific targets or through self-association. Notable examples of such disorder-to-order transitions include amyloidogenic proteins like amyloid-β peptide (Aβ) and tau peptide in Alzheimer's disease, α-Synuclein in Parkinson's disease, and hIAPP in type 2 diabetes, and so on. These regions can aggregate into amyloid fibrils through β -sheet stacking, contributing to amyloidosis and related diseases. Although direct link between amyloid formation and neurodegenerative disease development is not fully understood, developing effective inhibitors of these amyloid peptides remains promising both for fundamental research and therapeutical advance.

We have developed a new class …

Students Exploring Careers In Occupational Therapy, Shayna Kymes, Mary Thelander

InterProfessional Education Research and Scholarship

To engage students from rural and underserved communities, the Occupational Therapy Graduate Program participated in a Students Exploring Careers in Health (SECiH) event. We introduced the students to Occupational Therapy (OT) during the morning and provided three examples of assessments during the afternoon portion. We chose to have them explore one handed baby dressing, name as many animals as they can in 60 seconds per the Animal Naming Test (ANT) and the Minnesota Spatial Relations Test. We chose these assessments as the ANT is an equipment free test that can be given bedside to test for minimal or covert hepatic …

Evaluating The Effectiveness Of Behavioral Skills Training For Teaching Implementation Of Natural Language Paradigm Program To Staff In An Early Intervention Setting, Abigail Kinnear

Theses

Due to the prevalence of language delays in children with ASD, it is important to provide effective treatment and ensure highly trained staff to implement language programs. Natural Language Paradigm (NLP) is a naturalistic approach that includes individualized motivating variables, natural reinforcers, and direct response to reinforcer contingencies to increase vocal communication and generalization of skills. Behavioral skills training (BST) is an effective strategy that uses instructions, modeling, rehearsal, and feedback to teach staff to implement specific programs. The current study replicated Seiverling et al. (2009) study on evaluating the effectiveness of using BST to train three staff to implement …

Navigating Identity: An Examination Of Intersectional Discrimination And Suicidal Ideation Among Lgbq Latinx Individuals, Jaclyn Pachicano

Dissertations (1934 -)

Suicide is one of the leading causes of death in the United States, with LGBQ Latinx adults showing higher risk for suicidality and related mental health outcomes. Experiences of discrimination, including heterosexism and ethnic discrimination, are often connected to increased risk for suicidal ideation. In addition to intersectional experiences of discrimination, LGBQ Latinx people often feel an incompatibility between their sexuality and ethnic identity, known as conflicts in allegiances (CIA), possibly increasing risk of suicidal ideation. It remains unclear what mechanisms connect intersectional discrimination and suicidal ideation. The current study expands on intersectional research by utilizing the Interpersonal Theory of …

“I’M Not Gonna Be Able To Do This For Much Longer:” Perspectives Of Parochial School Principals On Their Role In Operational Vitality And The Educational Marketplace, Kris Brough

LMU Theses and Dissertations

Catholic schools have confronted a complex array of challenges, including declining enrollments, shifting demographics, and financial strains affecting all stakeholders. Establishing effective leadership has been a persistent practical hurdle, particularly in parish-based schools operating within the local-executive model. This qualitative study delved into the experiences and perspectives of parochial school principals, focusing on their leadership role in operational vitality. Additionally, it examined how these principals navigate the evolving educational landscape and respond to emerging challenges. By gathering and analyzing narratives from principals, the study shed light on issues impacting operational vitality and institutional growth and calls for further exploration within …

Presence Of Pharmaceuticals And Personal Care Products In Sinkhole Lakes In West-Central Florida, Elzbieta Bialkowska-Jelinska

USF Tampa Graduate Theses and Dissertations

Pharmaceuticals and personal care products (PPCPs) are essential for human health, improving quality of life, and extending life expectancy. However, many of these chemicals have become significant environmental pollutants, particularly in lentic (lake) environments. One unintended source of PPCPs in natural environments is onsite wastewater treatment systems (OWTS), commonly known as septic tanks.

This study examines whether the seasonal variability of rainfall and soil saturation affects the assemblages and concentrations of PPCPs in a residential lake. The general premise of the dissertation was that with the onset of the wet season, PPCPs that had collected in the drainfields of the …

Role Of Sds-22/Pp1 Phosphatase In Polarizing The Germplasm Of Caenorhabditis Elegans Embryo, Aparna Nurni Ravi

Dartmouth College Ph.D Dissertations

During asymmetric cell division, cell polarity and cell cycle are tightly coupled to ensure robust segregation of cell fate determinants and generation of cellular diversity. In the one-cell C. elegans embryo, multiple cell cycle kinases regulate cell polarization and posterior segregation of germline fate determinants (germplasm). For example, PLK-1 kinase inhibits the retention of its germplasm substrate POS-1 in the anterior, driving POS-1 segregation to the posterior (Han et al., 2018). Additionally, MBK-2 kinase disassembles P granules in the anterior through phosphorylation of the P granule scaffold MEG-3, helping to drive P granule segregation to the posterior (Wang et al., …

27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Pei Luo, Valeria C Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu

Faculty, Staff and Students Publications

Oxysterols are metabolites of cholesterol that regulate cholesterol homeostasis. Among these, the most abundant oxysterol is 27-hydroxycholesterol (27HC), which can cross the blood-brain barrier. Because 27HC functions as an endogenous selective estrogen receptor modulator, we hypothesize that 27HC binds to the estrogen receptor α (ERα) in the brain to regulate energy balance. Supporting this view, we found that delivering 27HC to the brain reduced food intake and activated proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (POMCARH) in an ERα-dependent manner. In addition, we observed that inhibiting brain ERα, deleting ERα in POMC neurons, or chemogenetic inhibition of …

An Evaluation Of Marginalized Student-Athlete Mental Health, Access To And Utilization Of Support Services, Ashley Boles

Electronic Theses and Dissertations Archive

NCAA student-athletes (SAs) face unique challenges as they simultaneously navigate sports, adulthood, and academic demands. Research indicates that SAs experience mental health issues at rates similar to or higher than their non-athlete peers, yet they are often less likely to seek help as they experience possible contributing factors including lack of knowledge on how and where to seek services, and stigma, which can both discourage service utilization. This study examined the mental health concerns of 145 NCAA SAs, focusing on the impact of biopsychosocial (BPS) factors influenced by division, injury, and marginalization status. Using Engel’s BPS framework, which considers biological, …

The Relations Between Sexual Orientation, Perceived Benefits Of E-Cigarettes, And E-Cigarette Use, James Derek Morris

Electronic Theses and Dissertations Archive

Minimal research has explored differences in perceived benefits of e-cigarettes (i.e., vaping) by sexual orientation. The current study included 715 undergraduate students enrolled at a midsouth university who completed an online survey consisting of multiple items measuring the frequency of e-cigarette use, instrumental value of e-cigarettes, and perceived benefits of using e-cigarettes. Logistic regression was used to examine differences in vaping by sexual orientation. Logistic regression was used to explore whether sexual orientation served as a moderating factor between perceived benefits of e-cigarettes and vaping. Results indicated that four instrumental value and four vaping-specific perceived benefit items consistently predicted varying …

Two Essays On Auditor Ostracism And Authenticity, Kehinde Mayokun Ogunade

Electronic Theses and Dissertations Archive

The first essay investigates whether auditor race and voice have an impact on perceived ostracism. Drawing on social identity theory, I hypothesize that race and auditor voice could lead to feelings of ostracism and that authenticity will moderate the relationship between auditor race, voice, and ostracism. Using a 2×2 between-subject design, my findings indicate that auditor race does not have a significant impact on feelings of ostracism, whereas auditors feel more ostracized if they do not speak up. Additional analysis using the Hayes process model finds that authenticity moderates the relationship between auditor race and ostracism, even though race does …

A Study Of Bozza's Eighteen Etudes In The Form Of Improvisation For Horn And New Preparatory Etudes On The Works Of Bozza, James Austin Currence

Electronic Theses and Dissertations Archive

This document serves as an analysis of Eugene Bozza's Dix-Huit Études en Forme d'Improvisation pour Cor (1961), translated to Eighteen Etudes in the Form of Improvisation for Horn for the purposes of this document. I found and documented all motifs within the eighteen etudes, and categorized connections between them and Bozza's compositional ouerve as displayed in Dr. Lois Kuyper-Rushing's A Thematic Index of the Works of Bozza. My research takes inspiration from Dr. Kuyper-Rushing's work as well as Dr. Hsing-Fang Liu's research involving Bozza's use of “Adoptive Transcription”, or taking old melodies from previous works and using them in new …

Becoming An Active Anti-Racist: Exploring The Role Of White Critical Consciousness Development, Alexandria Heilmann Littlejohn

Electronic Theses and Dissertations Archive

The development of white individuals’ critical consciousness may play a role in fostering an anti-racist orientation and increasing engagement in anti-racism activism efforts, ultimately aiding in counteracting the deleterious effects of racism and oppression in the United States. The prevalence of whites upholding whiteness, white supremacy, and systems of power and oppression is well-documented yet there is little literature on how critical consciousness and an anti-racist orientation develops in white young adults. This constructivist grounded theory qualitative study addresses this gap by exploring the perceived life experiences that were influential on six white young adults' critical consciousness development and how …

A Historical, Rhetorical And Prescriptive Analysis Of The Iconic Black Eulogy As Prophetic Rhetoric, Pierre Louis Vincent

Electronic Theses and Dissertations Archive

While the rhetorical structure of the Black eulogy is rooted in the Aristotelian genre of eulogy in the Greek tradition, it continues to develop beyond that tradition in response to American socio-cultural exigencies that shape it. The Black eulogy has matured rhetorically through the hardships of slavery, structural oppression, and institutionalized violence to develop a prophetic rhetorical path to succor and give hope to a community weary from the diurnal inequities of oppression made palpable at the death of African American icons. Using a close reading, this study establishes the Black eulogy’s rhetorical foundation in the Aristotelian rhetorical genre, while …