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Better Together: Rural Community Collaboration In North Carolina's Cape Fear Region, Luke Santore, Lillie Greiman, Rayna Sage Sep 2025

Better Together: Rural Community Collaboration In North Carolina's Cape Fear Region, Luke Santore, Lillie Greiman, Rayna Sage

Independent Living and Community Participation

The disAbility Resource Center of North Carolina (dRC) has served the Cape Fear region of NC since 2008. The dRC holds to the philosophy that every individual has the right to maximize their abilities, live as independently as possible, and participate fully in their community. In rural NC, the delivery of formal support requires informal trust across people, places, and organizations. In this sense, dRC is a trust broker, facilitating relationships between informal rural support networks and the network of public and nonprofit service providers in the area. dRC does this through being embedded in rural places, earning trust person …


Fathers’ Lived Experiences After Their Children Experienced Child Sexual Abuse, Joan Michelle Lucien Sep 2025

Fathers’ Lived Experiences After Their Children Experienced Child Sexual Abuse, Joan Michelle Lucien

Walden Dissertations and Doctoral Studies

Child sexual abuse (CSA) is a global health crisis with deleterious consequences that violates children’s safety worldwide. Exact rates of CSA prevalence vary, as most cases of CSA are not disclosed. Survivors delayed or nondisclosure impedes early interventions to alleviate documented adverse effects of CSA. CSA survivors have an increased risk of suicidal ideation. This phenomenological study involved examining the lived experiences of adult fathers after their children experienced CSA. Finkelhor and Browne’s traumagenic dynamics framework guided this study. Traumagenic dynamics influence children’s cognitive and emotional functioning and distort their self-esteem, identity, worldview, and affective capacities. Stigmatization has been associated …


Development And Validation Of Susceptibility Assessment Tool In Homoeopathy (Sath) In Homoeopathic Clinical Practice, Divya Taneja, Anil Khurana, Kumar Dhawale, Renu Mittal, Padmalaya Rath, Abhijit Chakma, P. Dastagiri, Pritha Mehra, Hima Bindu Ponnam, Sunil Bhalinge, Rahul Suryavanshi, Sudha Dharmarajan, Parthasarathi Chakraborty, Pooja Kumari, Priyanka Nim, Subhash Kaushik Sep 2025

Development And Validation Of Susceptibility Assessment Tool In Homoeopathy (Sath) In Homoeopathic Clinical Practice, Divya Taneja, Anil Khurana, Kumar Dhawale, Renu Mittal, Padmalaya Rath, Abhijit Chakma, P. Dastagiri, Pritha Mehra, Hima Bindu Ponnam, Sunil Bhalinge, Rahul Suryavanshi, Sudha Dharmarajan, Parthasarathi Chakraborty, Pooja Kumari, Priyanka Nim, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Background: The homoeopathic philosophy identifies susceptibility as a key concept for prescribing a similimum, i.e., the indicated remedy and its potency. No validated instrument to measure susceptibility as high, medium or low could be identified in the literature. Objective: The present study was undertaken to identify the factors governing susceptibility assessment and to develop a simple tool for physicians to assess the susceptibility of the cases they see in their clinical practice. Material and Methods: A new questionnaire was developed using standardised procedures including item development, pilot testing, and psychometric evaluation. The psychometric properties of this pilot tool were assessed …


A Case Report On Multiple Renal Calculi And Bilateral Ovarian Cysts Treated With Homoeopathic Medicine Ignatia Amara, Pragya Sharma Sep 2025

A Case Report On Multiple Renal Calculi And Bilateral Ovarian Cysts Treated With Homoeopathic Medicine Ignatia Amara, Pragya Sharma

Indian Journal of Research in Homoeopathy

Introduction: Renal calculi are the most frequent urological illness. It can be caused by genetic, nutritional, or environmental factors. Ovarian cysts are fluid-filled structures which can be simple or complex. It can affect females of any age, whether during puberty or menopause. These disorders remain a medical challenge due to their complex aetiology and high incidence. Sometimes the symptoms grow so severe for the patient that treatment and time lost from work involve substantial costs, compromising their social, physical, psychological, and financial well-being. Case summary: This is a case report of a 38-year-old female having sharp cutting pain in lumbar …


Associations Between Adhering To 24-Hour Movement Guidelines And Anxiety Among Adolescents Across Intersectional Identities: Kyrbs 2020-2022., Suryeon Ryu, Eun Young Lee, Zan Gao Sep 2025

Associations Between Adhering To 24-Hour Movement Guidelines And Anxiety Among Adolescents Across Intersectional Identities: Kyrbs 2020-2022., Suryeon Ryu, Eun Young Lee, Zan Gao

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Identifying preventive measures for adolescent mental health is a global public health priority, as poor mental health heightens the risk of early death from related issues, including suicide. This study examined the associations between adherence to the 24-Hour Movement Guidelines and anxiety among a nationally representative sample of South Korean adolescents, using an intersectional identity framework.

METHODS: Data from the 2020-2022 Korea Youth Risk Behavior Surveys were analyzed. Adolescents aged 12-17 years were grouped based on adherence to guidelines: none, physical activity (PA), sedentary behavior (SB), sleep, two guideline combinations, and all three. Anxiety was the mental health outcome. …


Evaluation Of Robotic Swabbing And Fluorescent Sensing To Monitor The Hygiene Of Food Contact Surfaces, Siavash Mahmoudi, Clark Griscom, Pouya Sohrabipour, Yang Tian, Chaitanya Palleria, Philip G. Crandall, Dongyi Wang Sep 2025

Evaluation Of Robotic Swabbing And Fluorescent Sensing To Monitor The Hygiene Of Food Contact Surfaces, Siavash Mahmoudi, Clark Griscom, Pouya Sohrabipour, Yang Tian, Chaitanya Palleria, Philip G. Crandall, Dongyi Wang

Biological and Agricultural Engineering Faculty Publications and Presentations

Effective environmental monitoring is critical for preventing microbial and allergenic cross-contamination. However, manual swabbing methods, commonly used to verify hygienic conditions, are prone to inconsistent results because of variability in pressure, coverage, and techniques. Two novel solutions will be explored to address these challenges: a robotic swabbing system with tactile sensing control, and a fluorescence/absorbance spectrometer for non-contact, protein-based residue detection. The robotic system was evaluated against trained and untrained humans, measuring water pickup, surface coverage, and pressure consistency. Concurrently, the fluorescence system analyzed model poultry protein soil to correlate spectral patterns with contamination levels. The robotic system demonstrated statistically …


Ahp Priorities For Sustainable Healthcare Survey Data (2025), Clare Pettinger Sep 2025

Ahp Priorities For Sustainable Healthcare Survey Data (2025), Clare Pettinger

Faculty of Health Datasets

1) Data from a survey sent to UK AHP professionals about priorities for sustainable healthcare 2) summary of above survey to show top 5 priorities


Spartan Daily, September 24, 2025, San Jose State University, School Of Journalism And Mass Communications Sep 2025

Spartan Daily, September 24, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 12


Nontarget Effects Of Abamectin On Cysts And Three Larval Stages Of Marine Microcrustacean Artemia Franciscana, Hashem Khandan Barani, Sahel Pakzad Toochaei, Narjes Sanchooli Sep 2025

Nontarget Effects Of Abamectin On Cysts And Three Larval Stages Of Marine Microcrustacean Artemia Franciscana, Hashem Khandan Barani, Sahel Pakzad Toochaei, Narjes Sanchooli

Turkish Journal of Zoology

Abamectin (ABM) is a widely used pesticide in agriculture and aquaculture worldwide. However, limited information is available on the toxic impacts of ABM on nontarget marine organisms, necessitating further research to investigate the toxic impacts of ABM on marine life. Hence, this study examined the acute (0.5–2.5 μg/L for 24 and 48 h) and chronic (0.125–0.5 μg/L for 7 days) toxicity of ABM on the marine microcrustacean Artemia franciscana under different incubation conditions and at different stages of development. To simulate a more realistic environmental scenario, some of the exposure tests were conducted in the presence of food or with …


Cytotoxic And Genotoxic Effects Of Minor Temperature Changes And Zinc Oxide Nanoparticles Synthesized Using Plantago Major On Oncorhynchus Mykiss Gonadal Cells, Semra Çi̇çek, Sevda Işik Sep 2025

Cytotoxic And Genotoxic Effects Of Minor Temperature Changes And Zinc Oxide Nanoparticles Synthesized Using Plantago Major On Oncorhynchus Mykiss Gonadal Cells, Semra Çi̇çek, Sevda Işik

Turkish Journal of Zoology

Temperature changes and nanoparticle exposure have emerged as critical environmental stressors with potential cytotoxic and genotoxic effects on aquatic species. This study investigates the impact of zinc oxide nanoparticles (ZnO NPs), synthesized using Plantago major leaves, on Oncorhynchus mykiss gonadal (RTG-2) cells under different temperature conditions (23 °C, 24 °C, and 25 °C). RTG-2 cells were exposed to hexagonal ZnO NPs (≤100 nm) at concentrations of 6.25, 12.5, 25, 50, 75, and 100 μg/mL for 24 and 48 h. Cytotoxicity was assessed using the sulforhodamine B assay, and genotoxicity was evaluated via the comet assay. Results demonstrated that both temperature …


Physical Activity, Screen Time, Dietary Habits, And Health Outcomes Among Children And Adolescents In The Middle East And North Africa Region: A Narrative Review, Shaikha Eisa Alnaqbi, Rahab Sohail, Hadia M. Radwan, Maysm N. Mohamad, Falak Zeb, Haydar Hasan, Mona Hashim, Tareq Osaili, Sharifa Alblooshi, Ayesha S. Al Dhaheri, Lily Stojanovska, Leila Cheikh Ismail Sep 2025

Physical Activity, Screen Time, Dietary Habits, And Health Outcomes Among Children And Adolescents In The Middle East And North Africa Region: A Narrative Review, Shaikha Eisa Alnaqbi, Rahab Sohail, Hadia M. Radwan, Maysm N. Mohamad, Falak Zeb, Haydar Hasan, Mona Hashim, Tareq Osaili, Sharifa Alblooshi, Ayesha S. Al Dhaheri, Lily Stojanovska, Leila Cheikh Ismail

All Works

Background/objectives: Fat mass and obesity associated (FTO) gene and anthropometric measurements might be associated with breast cancer (BC) risk. This study aimed to assess the interactions between single nucleotide polymorphism (SNP) rs9939609 of the FTO gene, anthropometric indices, and BC risk among pre- and post-menopause women with overweight/obesity in Pakistan. Methods: This retrospective case–control study conducted on a convenience sample of 200 women divided into two groups: a case group comprised of 100 women diagnosed with BC, and control group comprised of 100 (age and menopausal status matched healthy women). Physical activity was assessed using validated questionnaire. Data on body …


Association Of Genetic Scores Related To Insulin Resistance With Neurological Outcomes In Ancestrally Diverse Cohorts From The Trans-Omics For Precision Medicine (Topmed) Program, Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M P Shade, Daniel Dicorpo, Xueqiu Jian, Donna K Arnett, Thomas R Austin, Alexa Beiser, Joshua C Bis, John Blangero, Eric Boerwinkle, Jan Bressler, Joanne E Curran, Charles S Decarli, Harsha Doddapaneni, Josée Dupuis, David W Fardo, Jose C Florez, Stacey Gabriel, Richard A Gibbs, David C Glahn, Namrata Gupta, Hector M González, Kevin A González, Konstantinos Hatzikotoulas, Kathleen M Hayden, Susan R Heckbert, Bertha Hidalgo, Alicia Huerta-Chagoya, Timothy M Hughes, Sharon L R Kardia, Charles L Kooperberg, Lenore J Launer, W T Longstreth, Ravi Mandla, Rasika A Mathias, Andrew P Morris, Thomas H Mosley, Ilya M Nasrallah, Paul Nyquist, Bruce M Psaty, Qibin Qi, Laura M Raffield, Nigel W Rayner, Alexander P Reiner, Claudia L Satizabal, Elizabeth Selvin, Magdalena D R Sevilla-Gonzalez, Albert V Smith, Jennifer A Smith, Kirk Smith, Beverly M Snively, Lorraine Southam, Tamar Sofer, Ken Suzuki, Henry J Taylor, Miriam S Udler, Karine A Viaud-Martinez, Sylvia Wassertheil-Smoller, Alexis C Wood, Lisa R Yanek, Xianyong Yin, Alisa K Manning, Jerome I Rotter, Stephen S Rich, James B Meigs, Myriam Fornage, Sudha Seshadri, Alanna C Morrison, Topmed Neurocognitive Working Group, Topmed Diabetes Working Group Sep 2025

Association Of Genetic Scores Related To Insulin Resistance With Neurological Outcomes In Ancestrally Diverse Cohorts From The Trans-Omics For Precision Medicine (Topmed) Program, Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M P Shade, Daniel Dicorpo, Xueqiu Jian, Donna K Arnett, Thomas R Austin, Alexa Beiser, Joshua C Bis, John Blangero, Eric Boerwinkle, Jan Bressler, Joanne E Curran, Charles S Decarli, Harsha Doddapaneni, Josée Dupuis, David W Fardo, Jose C Florez, Stacey Gabriel, Richard A Gibbs, David C Glahn, Namrata Gupta, Hector M González, Kevin A González, Konstantinos Hatzikotoulas, Kathleen M Hayden, Susan R Heckbert, Bertha Hidalgo, Alicia Huerta-Chagoya, Timothy M Hughes, Sharon L R Kardia, Charles L Kooperberg, Lenore J Launer, W T Longstreth, Ravi Mandla, Rasika A Mathias, Andrew P Morris, Thomas H Mosley, Ilya M Nasrallah, Paul Nyquist, Bruce M Psaty, Qibin Qi, Laura M Raffield, Nigel W Rayner, Alexander P Reiner, Claudia L Satizabal, Elizabeth Selvin, Magdalena D R Sevilla-Gonzalez, Albert V Smith, Jennifer A Smith, Kirk Smith, Beverly M Snively, Lorraine Southam, Tamar Sofer, Ken Suzuki, Henry J Taylor, Miriam S Udler, Karine A Viaud-Martinez, Sylvia Wassertheil-Smoller, Alexis C Wood, Lisa R Yanek, Xianyong Yin, Alisa K Manning, Jerome I Rotter, Stephen S Rich, James B Meigs, Myriam Fornage, Sudha Seshadri, Alanna C Morrison, Topmed Neurocognitive Working Group, Topmed Diabetes Working Group

The Brown Foundation: Institute of Molecular Medicine

To better characterize the potential biological mechanisms underlying insulin resistance (IR) and dementia, we derive cross-population and population specific polygenic scores [PSs] for fasting insulin and IR-related partitioned PSs [pPSs]. We conduct a cross-sectional study of the associations of these genetic scores with neurological outcomes in >17k participants (36% men, mean age 55 yrs) from the Trans-Omics for Precision Medicine (TOPMed) program (50% Non-Hispanic White, 23% Black/African American, 21% Hispanic/Latino American, and 4% Asian American). We report significant negative associations (P <  0.002) of the cross-population (P = 1.3 × 10-5) and European (PEA = 3.0 × 10-8) fasting insulin PSs with total cranial volume, and of a metabolic syndrome European PS with general cognitive function (BEA = -0.13, PEA = 0.0002) and lateral ventricular volume (BEA = 0.09, PEA = 0.002). We identify suggestive negative associations (P <  0.007) of metabolic syndrome and obesity pPSs with general cognitive function, and of lipodystrophy pPSs with total cranial volume. A higher genetic predisposition to IR is associated with lower brain size, and a genetic predisposition to specific IR-related type 2 diabetes subtypes, such as metabolic syndrome and mechanisms of IR mediated through obesity and lipodystrophy, is potentially involved in cognitive decline.


The Mini Nurse Academy: Diversifying Nursing Through Partnership And Community Engagement, Valerie Clary-Muronda, Clarissa Collier Sep 2025

The Mini Nurse Academy: Diversifying Nursing Through Partnership And Community Engagement, Valerie Clary-Muronda, Clarissa Collier

International Nursing Research Congress (INRC)

Purpose To describe the implementation and evaluation of a community engagement program using the NBNA Collaborative Community Health Model to address health equity by educating school students about health literacy and careers in nursing.

Global Health Equity Lack of diversity within the nursing profession contributes to persistent health disparities (Bartlett et al., 2022). Evidence suggests that a nursing population that mirrors the diversity of communities served is more likely to improve health outcomes. The Mini Nurse Academy (MNA) offers an innovative approach to increasing the diversity in nursing by introducing elementary school students to the nursing profession while educating them …


An Observational Study Of Personalized Mhealth To Promote Wellness In Healthcare Workers, Mary S. Mccarthy Sep 2025

An Observational Study Of Personalized Mhealth To Promote Wellness In Healthcare Workers, Mary S. Mccarthy

International Nursing Research Congress (INRC)

Background: Healthcare workforce resilience weakened during and after the pandemic. Nutrition, physical activity, and sleep deficits further diminish health status. Providing just-in-time resources may promote healthier behaviors in direct-care hospital staff. We had two study aims: 1) coach healthcare workers (HCWs) to make lifestyle changes that enhance wellness, and 2) compare high and low engagement with mHealth resources to achieve recommendations for cardiometabolic health.

Methods: In this 1-year prospective observational study, HCWs had 24/7 access to a dashboard built for personalized health messages and wore an activity and sleep tracker continuously. On-demand UVB phototherapy was available to boost vitamin D …


The Effects Of Lactation Practices On Lactational Amenorrhea: A Systematic Review, Helen Baker, Anna Newton-Levinson, Sharon Leslie Sep 2025

The Effects Of Lactation Practices On Lactational Amenorrhea: A Systematic Review, Helen Baker, Anna Newton-Levinson, Sharon Leslie

International Nursing Research Congress (INRC)

Background: Lactational amenorrhea (LA) is a contraceptive method that suppresses ovulation postpartum through frequent and exclusive breastfeeding, with up to 98% effectiveness in the first six months if practiced optimally (Curtis et al., 2024). LA relies on consistent breastfeeding intervals and nipple stimulation, which inhibit gonadotropin-releasing hormone (GnRH) secretion (McNeilly, 2001). Factors such as supplemental feeding, breast pump use, and early return to work may reduce LA's efficacy (Stuebe & Chen, 2022). This review assesses the impact of various lactation practices on LA to provide current insights and support informed counseling on breastfeeding as a contraceptive method.

Methods: Following PRISMA …


Gathering At The Table: Using Food To Heal On One’S Grief Journey, Jamie B. Daugherty, Jada Staat, Julie Rachford Sep 2025

Gathering At The Table: Using Food To Heal On One’S Grief Journey, Jamie B. Daugherty, Jada Staat, Julie Rachford

Journal of Community Engagement and Higher Education

This research study explored the registered dietitian nutritionist’s (RDN) role and impact while supporting those on their grief journey. Data collection methods included a focus group, journaling, workshop evaluations, and photo elicitation. Qualitative data analysis highlighted three themes emerging from a six-week culinary nutrition education support workshop: providing intention, building community, and showcasing RDNs as encouraging companions, by contributing their skills of nutrition education and hands-on culinary applications, supporting individuals continuing to grieve.


Carry On: A Multi-Campus Faculty Perspective On The Barriers And Facilitators To Implementing Service Learning Curriculum During A Global Pandemic, Adrianne Widaman, Kirsten Leisses Tuck Sep 2025

Carry On: A Multi-Campus Faculty Perspective On The Barriers And Facilitators To Implementing Service Learning Curriculum During A Global Pandemic, Adrianne Widaman, Kirsten Leisses Tuck

Journal of Community Engagement and Higher Education

Service learning (SL) faculty faced substantial and unique challenges during the COVID-19 pandemic. The purpose of this study was to explore SL faculty perspectives during the crisis. Higher education faculty who taught SL designated courses during 2020/2021 identified and prioritized challenges and strategies to teaching SL courses without direct person contact. A total of 144 unique responses were collected from 16 faculty from 5 universities using the nominal group technique, a qualitative and quantitative method. Highly ranked themes included the emotional burden felt by the faculty, decreased student learning, a lack of faculty time, the need for alternative assignments, and …


Promoting Healthy Aging Through An Intergenerational Service-Learning Course, Tricia Pierce, Eric Hubbard, Shalini Persaud Sep 2025

Promoting Healthy Aging Through An Intergenerational Service-Learning Course, Tricia Pierce, Eric Hubbard, Shalini Persaud

Journal of Community Engagement and Higher Education

This case study examines combining service-learning (SL) with an intergenerational exercise program using undergraduate kinesiology students. The purpose was to explore how SL increases confidence, social responsibility, and leadership growth while addressing community needs. Students led biweekly exercise sessions for older adults over six weeks. Reflections demonstrated mutual benefits, including improved activity levels, reduced social isolation, and strengthened community connections.


Fish Oil And Vernonia Amygdalina Leaves-Supplemented Biscuits Increased Insulin Secretion And Suppressed Pro-Inflammatory Cytokines In Type 2 Diabetic Wistar Rats, Omolola Soji-Omoniwa, Uthman Olanrewaju Abdulazeez, Christfavour Oluwaseyi Oloba, Samuel Olajuwon Kolawole, Johnson Opeyemi Olayinka, Emmanuel Olorunleke Oludipe, Anuoluwapo Faith Ajediti, Habib Tajudeen Yusuf Sep 2025

Fish Oil And Vernonia Amygdalina Leaves-Supplemented Biscuits Increased Insulin Secretion And Suppressed Pro-Inflammatory Cytokines In Type 2 Diabetic Wistar Rats, Omolola Soji-Omoniwa, Uthman Olanrewaju Abdulazeez, Christfavour Oluwaseyi Oloba, Samuel Olajuwon Kolawole, Johnson Opeyemi Olayinka, Emmanuel Olorunleke Oludipe, Anuoluwapo Faith Ajediti, Habib Tajudeen Yusuf

Al-Bahir

This research determined the effect of fish oil and Vernonia amygdalina-enriched biscuits (FVSB) on insulin sensitivity and inflammatory cytokines in type 2 diabetic rats. Forty-nine male rats were grouped into seven, i.e. A-G. Type 2 diabetes (T2DM) was induced in groups B-G by administering 230 mg/kg body weight [BW] NAD (ip) and 65 mg/kg BW streptozotocin (ip). Group A represented the control (Non-diabetic + unsupplemented biscuit), B (untreated diabetic), C (diabetic + 120 mg/kg BW metformin), D-F (diabetic + FVSB at 1g, 2g and 3g leaf inclusion respectively), and G (diabetic + conventional biscuit). The experiment lasted 35 days, …


Infantile Hypertriglyceridemia Secondary To Gpd1 Defects: An Underdiagnosed Differential Of Infantile Hepatomegaly And Hepatic Steatosis, Snigdha Verma, Vikrant Sood, Bikrant Bihari Lal, Rajeev Khanna, Chhagan Bihari, Seema Alam Sep 2025

Infantile Hypertriglyceridemia Secondary To Gpd1 Defects: An Underdiagnosed Differential Of Infantile Hepatomegaly And Hepatic Steatosis, Snigdha Verma, Vikrant Sood, Bikrant Bihari Lal, Rajeev Khanna, Chhagan Bihari, Seema Alam

Journal of Pediatric Genetics

Disorders of carbohydrate and lipid metabolism are the leading underlying etiologies of hepatomegaly and hepatic steatosis in young children. With ever increasing access to genetic analysis methods, previously hitherto unknown and under-diagnosed entities like transient infantile hypertriglyceridemia, have been recently added as one of the differential diagnosis for the same. As per the available literature, this entity has been reported to have a benign course, however with increasing number of reported cases, there is yet much more to explore. We hereby present two such pediatric cases presenting with infantile onset hepatomegaly and hepatic steatosis along with a review of literature …


Systematic Exploration Of Trpv6 Variants In Pancreatitis: Unraveling Genetic Associations And Pathophysiological Insights Through Comprehensive Systematic Review And In-Silico Analysis, Omar Alomari, Rumeysa Yegin, Muhammed Edib Mokresh, Ghazaleh Kokabi Ghahremanpour, Nurullah Komurcu, Elif Nur Ari, Magda Wojtara, Ali Karaman, Abdulqadir J. Nashwan Sep 2025

Systematic Exploration Of Trpv6 Variants In Pancreatitis: Unraveling Genetic Associations And Pathophysiological Insights Through Comprehensive Systematic Review And In-Silico Analysis, Omar Alomari, Rumeysa Yegin, Muhammed Edib Mokresh, Ghazaleh Kokabi Ghahremanpour, Nurullah Komurcu, Elif Nur Ari, Magda Wojtara, Ali Karaman, Abdulqadir J. Nashwan

Journal of Pediatric Genetics

Background and Aims: The transient receptor potential vanilloid subfamily member 6 (TRPV6), a calcium-selective channel, is crucial for intracellular calcium (Ca2+) transport, impacting the maintenance of Ca2+ homeostasis in the pancreas. Variants in the TRPV6 gene have been associated with disruptions in calcium balance, potentially contributing to chronic pancreatitis (CP). This systematic review aims to unravel the connections between TRPV6 gene variants and pancreatitis, with a particular focus on CP. Additionally, we conducted an in-silico co-expression analysis to explore the interrelationships among validated genetic variants associated with pancreatitis pathophysiology and TRPV6 gene variants . Methods: A comprehensive literature search was …


Goals And Achievements, Catherine Stemmans Paterson Sep 2025

Goals And Achievements, Catherine Stemmans Paterson

Journal of Community Engagement and Higher Education

This article reflects on the goals and recent achievements of The Journal of Community Engagement and Higher Education(JCEHE). It also describes the articles published in the JCEHE’s fourth issue of volume fourteen.


Building Community One Structure At A Time: A Partnership Between Social Work And Landscape Architecture Students, Kenya M. Cistrunk, Elizabeth P. Tofte, Juriel A. Rogers Sep 2025

Building Community One Structure At A Time: A Partnership Between Social Work And Landscape Architecture Students, Kenya M. Cistrunk, Elizabeth P. Tofte, Juriel A. Rogers

Journal of Community Engagement and Higher Education

Experiential learning is invaluable when promoting interdisciplinary approaches to teaching complex issues. This article reports on a five-week collaboration between undergraduate stu-dents in social work and landscape architecture courses, project impetus being a common-reading text. Students (n=54) constructed three-dimensional models of children’s playgrounds and prepared academic posters describing restorative interventions based on their service-learning experiences with community partners. Projects were displayed at university-sponsored workshops. Participation in common reading programs has promising implications for interdis-ciplinary collaboration.


Sharing A Vision With An International Partner Through Photographs, Leah S. Dunn, Diane Ceo-Difrancesco, Rakhi Srivastava Sep 2025

Sharing A Vision With An International Partner Through Photographs, Leah S. Dunn, Diane Ceo-Difrancesco, Rakhi Srivastava

Journal of Community Engagement and Higher Education

The purpose of this study was to establish a shared vision between the academic program and the international service-learning partner. Through the use of photovoice (Collier & Collier, 1986), we conducted a needs assessment to determine the partner’s priorities. Analysis of inter-view transcripts and photos yielded themes representing the partner’s needs and were the basis of the shared vision, adding clarity to the purpose of the experience.


Antioxidants And Metabolic Biomarkers: Clinical Insights In Breast Cancer Patients, Rania Kareem, Emad Yousif, Taghried Salman, Muna Bufaroosha Sep 2025

Antioxidants And Metabolic Biomarkers: Clinical Insights In Breast Cancer Patients, Rania Kareem, Emad Yousif, Taghried Salman, Muna Bufaroosha

AUIQ Technical Engineering Science

Breast cancer is the primary cause of cancer-related deaths among women and the most common life-threatening malignancy identified in this population. The second most common cause of cancer-related fatalities in women is breast cancer. According to the most recent Iraq Cancer Requisition, breast cancer is the most common kind of cancer in women in Iraq, making up almost one-third of all female malignancies. Total of 100 patients with breast cancer was used in this study and compared to 100 healthy groups. Serum levels of vitamin C, vitamin E, Triglycerides, HDL, prolactin, cysteine protease, glutathione peroxidase and glutathione reductase were measured …


Nrf2 Drives Activation-Driven Expansion Of Cd4+T Cells By Modulating Glucose And Glutamine Metabolism, Aprajita Tripathi, Debolina Dasgupta, Michael S. Dahabieh, Rachel Griffard-Smith, Anil Pant, Ashlyn Bugbee, Nanda Kumar Yellapu, Emily Burt, Ben H Y Choi, Abigail E. Ellis, Ryan D. Sheldon, Shailendra Giri, Devin Koestler, Russell G. Jones, Viveka Nand Yadav, Kalyani Pyaram Sep 2025

Nrf2 Drives Activation-Driven Expansion Of Cd4+T Cells By Modulating Glucose And Glutamine Metabolism, Aprajita Tripathi, Debolina Dasgupta, Michael S. Dahabieh, Rachel Griffard-Smith, Anil Pant, Ashlyn Bugbee, Nanda Kumar Yellapu, Emily Burt, Ben H Y Choi, Abigail E. Ellis, Ryan D. Sheldon, Shailendra Giri, Devin Koestler, Russell G. Jones, Viveka Nand Yadav, Kalyani Pyaram

Manuscripts, Articles, Book Chapters and Other Papers

Upon antigenic stimulation, CD4+T cells undergo clonal expansion elevating their bioenergetic demands and utilization of nutrients like glucose and glutamine. The nuclear factor erythroid-2-related factor 2 (Nrf2) is a well-known regulator of oxidative stress, but its involvement in modulating the metabolism of CD4+T cells remains unexplored. We report that Nrf2 protein levels are temporally regulated in activated CD4+T cells, with elevated expression during early activation followed by a decline. T cell-specific constitutive activation of Nrf2, by deletion of its negative regulator Keap1, enhances early activation and interleukin-2 (IL-2) expression, upregulates T cell receptor (TCR) signaling, and increases activation-driven expansion of …


Nonfinancial Factors Shape Food Insecurity Among U.S. Older Adults, Madonna Harrington Meyer, Colleen M. Heflin Sep 2025

Nonfinancial Factors Shape Food Insecurity Among U.S. Older Adults, Madonna Harrington Meyer, Colleen M. Heflin

Population Health Research Brief Series

Nonfinancial factors such as poor physical and mental health, lack of access to healthy food, and transportation challenges make it more difficult for older adults to obtain, prepare, and consume healthy food. Based on the book, Food for Thought: Understanding Older Adults Food Insecurity, this brief summarizes how nonfinancial factors function as both causes and consequences of food insecurity in old age.


Mt1-Mmp Inhibition Rejuvenates Ageing Brain And Rescues Cognitive Deficits In Obesity, Pallavi Asthana, Liguo Li, Lin Lu, Jiayan Wu, Shuo Zhang, Ningning Li, Sheung Kin Ken Wong, Susma Gurung, Yijing Zhang, Yuwan Lin, Yufeng Peng, Zongtang Xu, Kui Ming Chan, Lixiang Zhai, Aiping Lyu, Zhao-Xiang Bian, Xin Ge, Ashok Iyaswamy, Min Li, Ya Su, Zhongjun Zhou, Pingyi Xu, Hoi Leong Xavier Wong Sep 2025

Mt1-Mmp Inhibition Rejuvenates Ageing Brain And Rescues Cognitive Deficits In Obesity, Pallavi Asthana, Liguo Li, Lin Lu, Jiayan Wu, Shuo Zhang, Ningning Li, Sheung Kin Ken Wong, Susma Gurung, Yijing Zhang, Yuwan Lin, Yufeng Peng, Zongtang Xu, Kui Ming Chan, Lixiang Zhai, Aiping Lyu, Zhao-Xiang Bian, Xin Ge, Ashok Iyaswamy, Min Li, Ya Su, Zhongjun Zhou, Pingyi Xu, Hoi Leong Xavier Wong

The Brown Foundation: Institute of Molecular Medicine

Obesity has been linked to an increased risk of cognitive impairment and dementia in later life. Although aging and obesity are both associated with cognitive decline, it remains unclear how they interact to affect cognitive function across the lifespan and how brain function might mediate their relationship with cognition. Our previous findings and other studies have shown that membrane type 1-matrix metalloproteinase (MT1-MMP/MMP14), which increases with age, regulates energy homeostasis. Inhibiting MT1-MMP improves insulin sensitivity, reduces body fat, and lowers serum cholesterol. Here, we demonstrate that MT1-MMP links neuroinflammation to cognitive decline in aging and obesity. Inflammatory responses in the …


Improving Staff Knowledge On Hourly Rounding Using The 4ps To Reduce The Fall Rate, Chukwuemeka Igboanugo Sep 2025

Improving Staff Knowledge On Hourly Rounding Using The 4ps To Reduce The Fall Rate, Chukwuemeka Igboanugo

Walden Dissertations and Doctoral Studies

I designed this Doctor of Nursing Practice (DNP) project to develop an educational program that increases staff knowledge of hourly rounding using an evidence-based approach, specifically pain, position, potty, and possession (the 4Ps), to prevent falls among residents in a long-term care facility. According to facility leadership, the observed gap in practice was the nursing staff members’ lack of knowledge in performing hourly rounding. The facility’s fall records for the lockdown units indicated a surge in fall rate, with 32 falls among 62 residents per month, reflecting a need for action. The practice-focused question guiding the project was: For staff …


Understanding Cancer Survivorship Care Needs Using Amazon Reviews: Content Analysis, Algorithm Development, And Validation Study, Liwei Wang, Qiuhao Lu, Rui Li, Taylor B. Harrison, Heling Jia, Ming Huang, Heidi Dowst, Rui Zhang, Hoda Badr, Jungwei W. Fan, Hongfang Liu Sep 2025

Understanding Cancer Survivorship Care Needs Using Amazon Reviews: Content Analysis, Algorithm Development, And Validation Study, Liwei Wang, Qiuhao Lu, Rui Li, Taylor B. Harrison, Heling Jia, Ming Huang, Heidi Dowst, Rui Zhang, Hoda Badr, Jungwei W. Fan, Hongfang Liu

Department of Medical Oncology Faculty Papers

BACKGROUND: Complementary therapies are being increasingly used by cancer survivors. As a channel for customers to share their feelings, outcomes, and perceived knowledge about the products purchased from e-commerce platforms, Amazon consumer reviews are a valuable real-world data source for understanding cancer survivorship care needs.

OBJECTIVE: In this study, we aimed to highlight the potential of using Amazon consumer reviews as a novel source for identifying cancer survivorship care needs, particularly related to symptom self-management. Specifically, we present a publicly available, manually annotated corpus derived from Amazon reviews of health-related products and develop baseline natural language processing models using deep …