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Essential Amino Acid (Eaa) Regulation Of Skeletal Muscle Protein Turnover With Age, Mary Komp

Graduate Theses and Dissertations

Skeletal muscle (SM) is vital for both long term health and quality of life. Recent research suggests an increase in catabolic signals with age triggers pathologic conditions, such as sarcopenia. Although results from in vitro studies model how EAA can regulate muscle protein synthesis (MPS), the relevance of these models to muscle protein breakdown (MPB) and the presence of physiological EAA concentrations remains to be established. Therefore, the objective of this study was to determine the effects of a low, normal, and supra physiological dose of EAA (0.2, 1.0, and 3.0 x EAA) in a young (passages 2-10) and aging …

Multi Elemental Analysis Of Cannabis Oil Based Products Using Icpms And Microwave Assisted Digestion., Kevin Trevon Marchbanks-Owens

Theses (2016-Present)

Due to the presence of CBD-(cannabidiol), bioavailable elements as well as industry versatility and relatively low levels of toxicity to the environment. CBD oils have driven the overall demand for Cannabis based plant products in the commercial and medical sector. However, dependent upon the environmental circumstances upon which these plants are grown can leave them susceptible to toxic heavy metal exposure. In fact, the natural metabolism of Cannabis plants makes them a hyperaccumulator of trace metals. This creates a severe health risk for CBD product consumers especially for more vulnerable populations with pre-existing conditions. Furthermore, the risk of heavy metal …

Regulation Of C-C Chemokine Receptor 7 (Ccr7) Ligand-Mediated Internalization And Chemotaxis By G Protein-Coupled Receptor Kinase Family 4 (Grk-4, 5, 6) In Human Pediatric T-Cell Acute Lymphoblastic Leukemia (T-All), Eduardo Elias Chaib

Open Access Theses & Dissertations

Background and Significance: The Hispanic population is disproportionally affected by T-ALL (T-cell acute lymphoblastic leukemia) when compared to other races in the US. C-C Chemokine Receptor 7 (CCR7) in T-ALL is used during disease progression, and may lead to migration of cancerous cells into the Central Nervous System (CNS) of patients. Goals and Objectives: This project aims to find relevant rates and risk factors for T-ALL for the Hispanic population in the US/Mexico border region. The other aim is to assess the effect of the G protein-coupled Receptor Kinase 4 (GRK-4) family proteins on migration and receptor internalization through CCR7 …

The Role Of Map Kinase Phosphatase-5 In Cardiac Adaptations To Endurance Exercise, Jaime Alfredo Perales

Open Access Theses & Dissertations

Endurance Exercise is a form of exercise that provides many benefits to the human body. Primarily, the cardiac muscle endures many cardiac adaptations in response to Endurance Exercise. But the mechanisms that are involved within these adaptations remains to be fully understood. MAPK or mitogen-activated protein kinase is a well know signaling pathway that promotes many cardiac benefits such as cell proliferation, protein synthesis and cell differentiation. Although this pathway is activated due to its upstream kinase (MKKs), the research presented focuses on the relationship and mechanisms involved in mitogen kinase phosphatase (MKPs) specifically (MKP-5). The research presented hopes to …

Contribution Of A Higher Educational Institution Towards Advancing Sustainability In The West Texas Paso Del Norte Region, Anand Raj

Open Access Theses & Dissertations

Sustainability comprises primarily three elements; environmental, social, and economic, which can be considered the keys to humanityâ??s survival and wellbeing. The pillars can alternately be given informal names: planet, people, and profit. Sustainability is achieved by effectively utilizing available resources through different sustainable development efforts. Generally, groups or entities come together to create sustainable impact in the three primary elements discussed here. City councils, businesses, and higher education institutions are just a few of the entities that engage in sustainability efforts. It is valuable to appraise the role played by a higher education institution in advancing sustainability in the context …

The Experience Of Immigration And Aging On The Health Of Older Adults In The El Paso, Texas, Border Region, Sonia Lizet Ramos

Open Access Theses & Dissertations

Healthcare access continues to be a problem for immigrant populations in the United States, especially for Latino immigrants at the US-Mexico border. There is limited social research examining the experience of access to health care of older adult Latino immigrants during their life course in the U.S. In U.S.-Mexico border communities, documented and undocumented residents face unique experiences when accessing health care. This thesis focuses on understanding the intersectionality of the immigration process and health care access of older adult Latino immigrants on the U.S.- Mexico. Using qualitative data collected from participants living in the County of El Paso, Texas, …

Understanding Mental Health Related Factors And High-Risk Behaviors Among Emerging Adults Through The Lens Of The Social-Ecological Model, Sheralyn Sanchez

Open Access Theses & Dissertations

Emerging adulthood is a transitional period where young adults are faced with new challenges while exploring their identity and experimenting with life choices. However, during this time, young adults are more at risk of engaging in risky behaviors. The focus on emerging adults is important since the health and development of young adults can influence their health and life outcomes. The social-ecological model was used to understand the relationship between mental health and high-risk behaviors, in addition to the influence from different ecological factors (individual, relationship, and community). This study examined the relationship between the presence of mental health issues …

Effects Of Providing Novel Feedstuffs To Livestock On Production And Skeletal Muscle Growth, Laura A. Motsinger

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

As the population increases and available land for food production decreases, it is necessary for livestock producers to continually work towards increasing livestock production efficiency. In livestock operations, feed accounts for the majority of input costs associated with raising livestock. As such, it is necessary to improve growth and production of livestock animals, while also optimizing feed utilization. Different feedstuffs can be included in the diet of livestock animals to maximize growth and production. However, the effects of some of these novel feedstuffs on growth and production of livestock animals has not been elucidated. As such, we investigated the effects …

Greater Sage-Grouse Brood Responses To Livestock Grazing In Sagebrush Rangelands, Hailey Peatross Wayment

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The distribution and abundance of the greater sage-grouse (Centrocercus urophasianus; sage-grouse) have declined in the last 60 years. Range contractions and population declines have been attributed to loss and fragmentation of their sagebrush (Artemisia spp.) habitats. Grazing by livestock remains the predominant anthropogenic land-use across sagebrush ecosystems in North America, occurring on 87% of remaining sage-grouse habitat. Most of the peer-reviewed literature reports the potential for negative impacts of sagebrush reduction treatments, to increase livestock forage, on sage-grouse habitat. However, few studies have linked livestock grazing at the landscape level to vital rates (e.g., nest initiation rates, …

Impact Of Ph And Palmitic Acid On Ruminal Fermentation And Microbial Community Composition, Lexie Padilla

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The objective of this study was to evaluate the effects of dietary palmitic acid and pH on rumen fermentation, fiber digestibility, and bacterial community composition. The two factors in the experiment were palmitic acid treatment and pH treatment. Palmitic acid treatments included a control diet compared to a diet containing 1.5% palmitic acid. pH treatments included normal pH (6.6 to 7.0) compared to low pH (6.0 to 6.4). Rumen fluid from a cow was added to artificial rumens to study the effects of the two treatments relative to fermentation and changes within the microbial community. Results of the study showed …

Editorial: Fat Metabolism And Deposition In Poultry: Physiology, Genetics, Nutrition And Interdisciplinary Research, Volume I, Sami Dridi, Craig W. Maynard, Jie Wen, Elizabeth Gilbert

Poultry Science Faculty Publications and Presentations

Editorial on the Research Topic: Fat metabolism and deposition in Poultry: Physiology, Genetics, Nutrition and Interdisciplinary Research, Volume I

Genome-Wide Association Study And Genomic Prediction For Bacterial Wilt Resistance In Common Bean (Phaseolus Vulgaris) Core Collection, Bazgha Zia, Ainong Shi, Dotun Olaoye, Haizheng Xiong, Waltram Ravelombola, Paul Gepts, Howard F. Schwartz, Mark A. Brick, Kristen Otto, Barry Ogg, Senyu Chen

Horticulture Faculty Publications and Presentations

Common bean (Phaseolus vulgaris) is one of the major legume crops cultivated worldwide. Bacterial wilt (BW) of common bean (Curtobacterium flaccumfaciens pv. flaccumfaciens), being a seed-borne disease, has been a challenge in common bean producing regions. A genome-wide association study (GWAS) was conducted to identify SNP markers associated with BW resistance in the USDA common bean core collection. A total of 168 accessions were evaluated for resistance against three different isolates of BW. Our study identified a total of 14 single nucleotide polymorphism (SNP) markers associated with the resistance to BW isolates 528, 557, and 597 …

Effect Of Cyclic Heat Stress On Hypothalamic Oxygen Homeostasis And Inflammatory State In The Jungle Fowl And Three Broiler-Based Research Lines, Giorgio Brugaletta, Elizabeth Greene, Alison Ramser, Craig W. Maynard, Travis Tabler, Federico Sirri, Nicholas B. Anthony, Sara K. Orlowski, Sami Dridi

Poultry Science Faculty Publications and Presentations

Heat stress (HS) is devastating to poultry production sustainability due its detrimental effects on performance, welfare, meat quality, and profitability. One of the most known negative effects of HS is feed intake depression, which is more pronounced in modern high-performing broilers compared to their ancestor unselected birds, yet the underlying molecular mechanisms are not fully defined. The present study aimed, therefore, to determine the hypothalamic expression of a newly involved pathway, hypoxia/oxygen homeostasis, in heat-stressed broiler-based research lines and jungle fowl. Three populations of broilers (slow growing ACRB developed in 1956, moderate growing 95RB from broilers available in 1995, and …

Blood Lead Levels In Minority Children: A Case Of Environmental Racism, Erick Rivera

Sociology & Criminal Justice Theses & Dissertations

Racial minorities in the United States have suffered from being disadvantaged. Among these disadvantages is environmental racism. This includes minority communities being ‘sacrifice zones’ for toxic waste and being exposed to lead poisoning. The purpose of this study is to examine differences in blood levels between white children and children of color. This research will follow a bivariate model for the first research question, “Do youth of color (under the age of 18) have higher BLLs than white children?” The bivariate model will look at the relationship between ethno-racial group and BLLs. Specifically, an analysis of variance (ANOVA) will be …

Nasogastric Feeding Tube/Dobhoff Placement: A Multidisciplinary Approach To The Management Of Malnutrition During Radiation Therapy In Patients With Head And Neck Cancer, Alexandra V. Coke, Marissa Gilbert, Sue Hill, Farzan Siddiqui

Radiation Oncology Articles

Background: Radiation therapy (RT)-associated oral mucositis, xerostomia, thick mucoid saliva, nausea/vomiting, and loss of taste may result in significantly compromised oral intake in patients undergoing treatment for head and neck cancers (HNC). Feeding tube placement allows patients to receive enteral nutrition and continue the planned course of treatment.

Objectives: RT-associated oral mucositis, xerostomia, and loss of taste may result in significantly compromised oral intake in patients undergoing treatment for head and neck cancers. We sought to determine if reactive nasogastric (NG) tube placement was an effective strategy for nutritional support in these patients and if invasive percutaneous endoscopic gastrostomy (PEG) …

Sarcoid Myelitis Masking As Multiple Sclerosis In An Otherwise Healthy 45-Year-Old: A Case Report, Jesse Lou, Brandon Trivax

Posters

No abstract provided.

The Synchronization Of Nocturnal Pollinator Behavior And Apple Flower Nectar Production, Madison Jennings

Biological Sciences Undergraduate Honors Theses

Insects perform an essential ecological service by facilitating the pollination of crops for food production worldwide. Recent declines in diurnal bee populations threaten food security and has led to growing concerns about existent pollination methods. Pollination contributions by native nocturnal insects have been documented to occur in a variety of systems, thought to be supported by the plant’s attractant and reward system. If this is the case, pollination of flowers by nocturnal vectors may be influenced by circadian cycles of nectar production and insect activity. To test this hypothesis, we recorded insect abundance of nocturnal pollinators periodically throughout the night …

Self-Rated Function And Delayed Onset Muscle Soreness (Doms) Responses To 6-Week Supplementation With Waters With Anti-Inflammatory Capabilities (Wac), Kristin Garner

Health, Human Performance and Recreation Undergraduate Honors Theses

Introduction: Researchers have examined the effects of sedentary lifestyles on diminished health outcomes and are pleading individuals to take on a more active lifestyle to prevent these. However, initial efforts to exercise are often dampened by delayed onset muscle soreness (DOMS) and muscle fatigue. This can greatly reduce exercise adherence, making it difficult for individuals to overcome this temporary discomfort. Background: Research has extensively evaluated nonsteroidal anti-inflammatory drugs (NSAIDs) and fruits as anti-inflammatory supplementation to treat DOMS. Berry-derived essences are more highly concentrated in anti-inflammatory substances than regular fruit juices, but there is minimal research on their effects on exercise …

Tiny Tusks Internship: Barriers To Breastfeeding Surrounding Neonatal Intensive Care Units, Quinn Owen, Brianna Purser

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Breastfeeding has proven itself beneficial to both baby and mother for many reasons. However, many mothers do not breastfeed their infants. In fact, only 1 in 4 mothers breastfeed for the first 6 months of life. Experiences in the clinical setting and knowledge gained as interns for Tiny Tusks, a breastfeeding and infant support group for sporting events at the University of Arkansas, sparked the desire to understand the staggering statistic.This literature review seeks to understand barriers to breastfeeding, specifically, barriers to breastfeeding as it pertains to neonatal intensive care units (NICU).

Understanding The Fate And Transport Of Per- And Polyfluoroalkyl Substances In Wastewater Systems: A New England Perspective, Sydney Kathleen Adams

Master's Theses and Capstones

This thesis explores the story of per- and polyfluoroalkyl substances (PFAS) in New England wastewater systems. PFAS compounds, known for their environmental persistence, toxic nature, and heavy integration into our daily lives, has recently become an infamous topic in environmental engineering due to the discovery of contaminated agricultural lands, water resources, and food systems. In response to these daunting discoveries, regulators have begun looking to reduce point source pollution of PFAS, including that of wastewater systems and facilities. As conduits of PFAS, wastewater systems funnel PFAS from industrial, commercial, and residential sources and emit them into the environment via aqueous …

Essential Tools For Sustainability Of A Student-Led, Pro-Bono Back School, Cory Brown, Rosalie Gutierrez, Jennifer Montes, Rondale Scruggs

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: In 2018, University of Nevada Las Vegas Doctor of Physical Therapy (DPT) students and faculty, in cooperation with a community partner, created a student-led pro bono Back School to address a gap in healthcare for underinsured individuals with low back pain in Southern Nevada. To support the sustainability of the Back School, the authors of this paper set out to develop a student club to recruit and train DPT students to volunteer in the program using a specifically designed electronic training manual. Overall, the aim was to encourage students to join the new club's leadership team to prepare future …

Efficacy And Benefits Of Providing A Screening Clinic For Performing Arts Students, Shaun Bean, Joanna Centeno, Elizabeth Williams

UNLV Theses, Dissertations, Professional Papers, and Capstones

In past years, University of Nevada, Las Vegas physical therapy students (UNLVPT) have provided UNLV dance students with screening clinics, injury evaluations, and treatment sessions to help address their need for direct and specialized services. Through this project, UNLVPT has worked to help reduce injury risk in dancers and provided treatment and rehabilitation for injuries that have occurred. Due to the COVID-19 pandemic, our group was unable to treat dancers in person over the course of the 2020-2021 school year. In response to these limitations, we worked to reformat our screening process to make it practical in a virtual setting. …

The Road Ahead: An Occupational Therapy Manual To Infant Development For Parents In The Nicu, Nicole Suzuki-Uyeno

UNLV Theses, Dissertations, Professional Papers, and Capstones

Occupational therapists have been collaborating with the parents of our tiniest patients in the neonatal intensive care unit (NICU) for quite some time. They have a wealth of information and expertise in the area on infant development and parent education. Admitting a baby to the NICU is a shock for most parents and can take a toll on a family. The role of the occupational therapist is to help educate the family and to provide the tools to safely take care of their baby and to smoothen the transition from the hospital to home.

In the NICU, the OT has …

Diurnal Regulation Of Exercise-Induced Myocardial Signaling And Transcription, Charli Aguilar

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Exercise is well known for its many benefits on the body and most notably the heart. Recent emphasis, and significant resources, have been dedicated to elucidating the molecular mechanisms through which exercise exerts its pluripotent beneficial effects on health and the prevention of disease. A continuous evolution in this field has sought to modulate and optimize exercise in various ways to maximize the benefits. In recent years, a growing appreciation for the impact of circadian rhythms has gained traction and their influence on many essential biological functions have been integrated into exercise physiology (i.e. - chrono-exercise), as well as …

Examining The Role Of Prosocial Tendencies And Social Anxiety In Hazardous Drinking Practices Among College Students, Helena M. Berlin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Over 40% of the United States (US) population aged 18 to 25 is enrolled at postsecondary institutions, and 31.4% of college students report risky alcohol use (i.e., binge drinking). Identifying risk and protective factors for this population is a public health priority. The primary objective of this study was to examine the additive and multiplicative relationship of prosocial tendencies and social anxiety on hazardous drinking (AUDIT scores). A secondary aim was to examine whether these relationships differed by participation in college organizations (Greekaffiliation, athletic participation, both, and neither). Cross-sectional data were collected from 9,196 college students (ages 18-25) from 12 …

Investigation Of Swimming Physiology And Swimming Kinematics While Wearing Different Triathlon Wetsuit Styles At Submaximal Front Crawl Swimming In Recreational Population, Boram Lim

UNLV Theses, Dissertations, Professional Papers, and Capstones

Triathlon wetsuits are commonly used due to the potential benefits in swimming performance and thermoregulation. Triathletes may select different wetsuit styles depending on many factors such as temperature regulation, swimming technique, body type, and training purpose. However, there is a lack of empirical evidence for how different wetsuit styles affect physiological responses and swimming kinematics during submaximal swimming intensity. Therefore, this studyaimed to investigate the physiological responses and swimming kinematics during submaximal intensity front crawl swimming while wearing different wetsuit styles. Fourteen participants (n=6 male, n=8 female; all recreational triathletes or swimmers) completed a swimming graded exercise test (GXT) wearing …

Time-Of-Day And Chronotype Dependent Effects Of Exercise On Migraine Load In People With Chronic Migraines: A Cross-Over Randomized Clinical Trial, Elias M. Malek

UNLV Theses, Dissertations, Professional Papers, and Capstones

Migraines are the most common cause of chronic pain. Effective, non-pharmacological strategies to reduce migraine load are needed. Exercise is an effective strategy, but it is unclear how exercise timing and temporal preference (chronotype) factors modulate the laudatory effects of exercise. Purpose: Determine the effects of; 1) time-of-day of exercise, and 2) exercise synchrony with one’s chronotype, on migraine load. Methods: Participants were 13 sedentary individuals with 8+ migraines/month (age = 30 ± 11 yrs, 167 ± 6 cm, 86 ± 28 kg). Participants were categorized into morning-/evening-types based on the Morning/Eveningness Questionnaire and instructed to complete 1 month of …

Is Dietary Teaching Via Telehealth Effective In Lowering Hgba1c In Adult Patients With Prediabetes Or Type 2 Diabetes?, Mia Mccallum-Crawford

UNLV Theses, Dissertations, Professional Papers, and Capstones

Prediabetes and Type 2 diabetes mellitus (T2DM) are two common conditions diagnosed in the primary care setting. Both conditions benefit from a healthy lifestyle, managing blood sugar levels, and getting diabetes self-management education and support (DSMES). Within the past two decades, the healthcare community in the US has witnessed a substantial rise in diabetes among adults. Overall, the self-management of diabetes continues to worsen nationally. The purpose of this project is to improve patients’ self-management of both Prediabetes and T2DM through nutrition and show how nutritional counseling via telehealth provided by a nurse practitioner can improve HgbA1C values over 3 …

Increasing Human Papillomavirus Vaccination Intent And Knowledge Through An Educational Intervention, Angelica E. Musumeci

UNLV Theses, Dissertations, Professional Papers, and Capstones

Human papillomavirus (HPV) is a widely discussed topic in healthcare as it affects patients of all genders and ages who partake in sexual activity. The most significant concern it poses to those at risk is HPV-related cancer. Fortunately, a vaccination exists that targets specific strains associated with these types of cancers. Despite evidence-based research supporting the vaccination’s efficacy and safety, lack of awareness and misinformation diminish the receipt of the vaccine and drive the lack of protection. Thus, educational interventions directed at parents and caregivers, which aims to improve their understanding of HPV and the vaccination’s benefits, is key to …

Identifying Gaps In Social Determinants Of Health Among Patients 65 Years And Older With Congestive Heart Failure: A Secondary Data Analysis, Sandra Pierre-Louis

UNLV Theses, Dissertations, Professional Papers, and Capstones

Congestive heart failure (CHF) is one of the most common healthcare problems for older adults. Because of its high and rising prevalence in this population and its significant influence on healthcare costs and quality of life, CHF is becoming a serious public health issue in the United States. More effective strategies for preventing and managing CHF in older people are desperately needed (Rich, 2015). The disease accounts for 3% of hospital admissions in the United States and affects more than 6.5 million Americans (White-Williams et al., 2020). Further, CHF is exacerbated by adverse social determinants of health (SDOH). This study …