Molecular Docking And Dynamics Simulation Studies To Predict Multiple Medicinal Plants’ Bioactive Compounds Interaction And Its Behavior On The Surface Of Denv-2 E Protein, Arief Hidayatullah, Wira Eka Putra, Muhaimin Rifa’I, Sustiprijatno Sustiprijatno, Diana Widiastuti, Muhammad Fikri Heikal, Hendra Susanto, Wa Ode Salma, Hilal Mulyadi

Karbala International Journal of Modern Science

The envelope protein (E) is a fusion class II protein that is essential for DENV fusion. We use two active compounds derived from commonly used plants in Indonesia: galangin and kaempferide. We ran a docking and 1000 ps molecular dynamic analysis with normal physiological parameters. During the simulation, galangin and kaempferide binding sites fluctuated. But chloroquine has lesser ligand mobility, hence keeping contact with fusion loops, whereas both drugs lose contact with hydrophobic pockets. However, the two active compounds have a more stable ligand configuration. Less than 2 Å alterations were seen in the RMSF simulation of the protein E …

Exploring The Self-Care Practices And Needs Of Entry-Level Nursing Students: A Pilot Project, Nancy Armstrong, Kristin M. Reid, Dana Todd

Faculty & Staff Research and Creative Activity

Self-care is often lacking in nursing students worldwide. The objectives for this study were to discover the current self-care practices of one group of entry level undergraduate nursing students, the students’ understanding of self-care, and the students’ preferences for self-care interventions aimed at improving self-care. Quantitative and quantitative measures were used to measure the students’ current self-care practices, needs, and recommendations for interventions to be used in future semesters to improve nursing student self-care. The students were found to generally be deficient in areas related to nutrition, obtaining healthcare information or guidance, pacing themselves to avoid exhaustion, and performing relaxation …

Effects Of Spatially Heterogeneous Lakeside Development On Nearshore Biotic Communities In A Large, Deep, Oligotrophic Lake, Michael F. Meyer, Ted Ozersky, Kara H. Woo, Kirill Shchapov, Aaron W. E. Galloway, Julie B. Schram, Emma J. Rosi, Daniel D. Snow, Maxim A. Timofeyev, Dmitry Yu. Karnaukhov, Matthew R. Brousil, Stephanie E. Hampton

School of Natural Resources: Faculty Publications

Sewage released from lakeside development can reshape ecological communities. Nearshore periphyton can rapidly assimilate sewage-associated nutrients, leading to increases of filamentous algal abundance, thus altering both food abundance and quality for grazers. In Lake Baikal, a large, ultra-oligotrophic, remote lake in Siberia, filamentous algal abundance has increased near lakeside developments, and localized sewage input is the suspected cause. These shifts are of particular interest in Lake Baikal, where endemic littoral biodiversity is high, lakeside settlements are mostly small, tourism is relatively high (~1.2 million visitors annually), and settlements are separated by large tracts of undisturbed shoreline, enabling investigation of heterogeneity …

Alfalfa Establishment And Management In South Carolina, Liliane Silva, Michael Mrshall, Jeremy Greene, Matias Aguerre

Livestock and Forages

Alfalfa is a perennial legume with high forage quality that can be used under grazing or hay management. This publication outlines establishment and management recommendations for alfalfa plantings in South Carolina.

Vol.50 N.04 August 18th 2022, Voice Media Ventures

Black Voice News

No abstract provided.

Food Insecurity In Perspective: Writing Food Access Into The Everyday, Colin James Lamusta

Honors Program Theses and Projects

The phrase ‘food insecurity’ has taken on a whole new meaning in the social consciousness. All around us the media and research have focused on the issue. In recent years the conditions of the pandemic, inflation, and unemployment have raised attention to the issue of food insecurity to a larger cross-section of American society. In consideration of this, I sought out the current research on food insecurity and the programs serving these food-insecure individuals to serve as a basis for a stage play. The research that proved most valuable in providing a base of inspiration for both the characters as …

Nutritional Cooking Program With Girls Inc., Taunton, Ma, Chantel Almanzar

Honors Program Theses and Projects

As a member of the Institutional Review Board-approved research team comprised of Dr. Maura Rosenthal, Dr. Angela Bailey, and Christina Elderbee, I led a six-week community-based health program that included cooking lessons for girls aged 10 to 13. I taught girls how to prepare healthful foods that they may cook with their family and friends at home. The larger project, Building Equity Through Collaboration with Girl's Inc., aims to study the outcomes of girls’ participation in after school and summer camp programs in 2021 and 2022. One part of this research, which intends to learn more about girls' current and …

From Fitspiration Posts To Food Shaming: Social Media’S Impact On Adolescent Girls’ Body Image, Madison Jones

Honors Program Theses and Projects

Social media is marketed as a way to connect and share with others all over the world—a fast way to connect to grandma down in Florida, do research from a university on the other side of the world, or even spark environmental change across the globe. So how, at the same time, can this be a harmful tool, one that has been identified as a cause of depression and even, in some cases, suicide in young girls? Social media sites like Instagram, FaceBook, and TikTok encourage users to post pictures and videos that show your “best self” alongside a rating …

Microbial Dimension Of Symbiosis And Dysbiosis In Fungus–Gardening Ants, Blake S. Bringhurst

Biology Theses

With symbiotic partners, the means by which a host obtain a symbiont influence the specificity between the host and the symbiont. One such system where symbiont specificity is seen to varying degrees is with higher attine ants. Higher attine ants have symbiotic relationships with the fungal cultivar they grow and the bacterial symbionts in their microbiomes. Among the higher attines, there are two broad groups of fungi. Most ants in the genus Trachymyrmex tend to grow Clade–B fungi, which are a group of undescribed Leucocoprinus species, while leaf–cutting ants in the genera Acromyrmex and Atta tend to grow Clade–A fungi …

Assessment Of Population Size, Survival, And Movement Behavior Of The Rare Frosted Elfin Butterfly, Breelyn Gilbert

Biology Student Scholarship

The frosted elfin butterfly (Callophrys irus) is a locally rare Lycaenaid with spotty distribution throughout the eastern United States. As host plant specialists, frosted elfins only lay eggs on two plant species. Yellow wild indigo (Baptisia tinctoria), one of the host plants for this species, is found in abundance at Gavins Pond (Foxboro MA). Since 2000, Massachusetts Butterfly Club members have been informally monitoring the frosted elfin population at this site; however, no systematic population surveys have been done. Using their data, I estimated annual population size from 2000 to 2022. In 2022, I also performed …

Effects Of Caffeine, Methylliberine, And Theacrine On Vigilance, Marksmanship, And Hemodynamic Responses In Tactical Personnel: A Double-Blind, Randomized, Placebo-Controlled Trial, Harry P. Cintineo, Marissa L. Bello, Alexa J. Chandler, Thomas D. Cardaci, Bridget A. Mcfadden, Shawn M. Arent

Faculty Publications

Background

Tactical athletes require fast reaction times (RT) along with high levels of vigilance and marksmanship performance. Caffeine has been shown to improve these measures but also results in increased blood pressure and jitteriness. Research on other purine alkaloids, such as methylliberine and theacrine, has suggested they do not increase blood pressure or jitteriness to the same extent, but their impact on tactical performance is unknown.

Methods

A between-subjects, randomized, placebo-controlled design was used to test the effects of placebo (PLA), 300 mg caffeine (CAF), and a combination of 150 mg caffeine, 100 mg methylliberine, and 50 mg theacrine (CMT) …

Floral Nutritional Value And Plant-Pollinator Interactions In Providence, Rhode Island, Gracey Sorensen

Biology Student Scholarship

Bees obtain nutrients from flowers. Pollen provides proteins and fats; nectar provides carbohydrates and some amino acids. With recent decline in pollinator populations, conservationists are interested in providing nutritious plants for pollinators. Counterintuitively, urban areas have the green space for pollinator friendly plantings. On Providence College’s urban campus, I examined how floral abundance and pollinator interactions correlate to the nutritional value of plant species. Quadrat surveys were performed within 53 quadrats through the Spring and Summer for plant-pollinator interactions. Pollen was collected from all flowering species and analyzed for nitrogen and carbon content using an elemental analyzer. Nectar samples were …

Snp Discovery In Proso Millet (Panicum Miliaceum L.) Using Lowpass Genome Sequencing, Rituraj Khound, Guangchao Sun, Ravi V. Mural, James C. Schnable, Dipak K. Santra

Department of Agronomy and Horticulture: Faculty Publications

Domesticated ~10,000 years ago in northern China, Proso millet (Panicum miliaceum L.) is a climate-resilient and human health-promoting cereal crop. The genome size of this self-pollinated allotetraploid is 923 Mb. Proso millet seeds are an important part of the human diet in many countries. In the USA, its use is restricted to the birdseed and pet food market. Proso millet is witnessing gradual demand in the global human health and wellness food market owing to its health-promoting properties such as low glycemic index and gluten-free. The breeding efforts for developing improved proso millet cultivars are hindered by the …

Effectiveness Of Group Interventions For Weight Loss For Youth: A Meta-Analytic Review, Monica Carolina Martinez

Theses and Dissertations

Introduction: Nearly 19.3% of children in the United States have obesity. There are several behavioral weight loss (BWL) programs available for children and adolescents that have proven effective in managing weight. Many of these treatments are delivered to groups of children rather than to individual youth. However, previous reviews of the literature have not explored the unique effects of group treatment modalities. Research has shown that social ties, particularly with peers, have an impact on adolescents' physical activity engagement and dietary habits. Therefore, it is important to explore how the interaction component of group delivered BWL treatments contributes to their …

Dietary Intake Among Children Attending Childcare Centers: Impact Of The New Cacfp Meal Guidelines, Jayna M Dave, Tzuan A Chen, Maha Almohamad, Sonia Cotto-Moreno

Children’s Nutrition Research Center Staff Publications

Through the Healthy, Hunger-Free Kids Act of 2010, USDA (US Department of Agriculture) made the first major changes in the CACFP (Child and Adult Care Food Program) meal and snack menu patterns. Childcare centers that serve low-income families qualify to participate and receive reimbursement for meals and snacks served. The purpose of this study was to assess what changes in children's dietary behaviors occurred as a result of the new CACFP meal pattern requirements. This study evaluated these changes at childcare centers operating in Houston and San Antonio, Texas, USA, areas enrolled in the CACFP, pre- (Spring 2016) and post-implementation …

August 18, 2022, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Child Health In Darfur, Sudan: Addressing The Effects Of Armed Conflict On Children's Health In Darfur, Judith Natukunda

Master's Projects and Capstones

ABSTRACT

Background: For 19 years, the Darfur region of Sudan has experienced unending civil unrest and war, resulting in more than 2 million deaths and over 4 million displaced persons. The war led to severe food insecurity, clean and safe drinking water shortages, high disease prevalence, destruction of infrastructure, and a broken health care system. Despite the interventions by the global community and various humanitarian agencies, over 2.8 million people are still displaced and living in IDP camps across Darfur. Over 300,000 children are living in neighboring Chad. The armed conflict led to high levels of child malnutrition, a high …

The Effects Of The Union Blockade On The Confederacy During The United States' Civil War, Ronald C. Piccirilli

Doctoral Dissertations and Projects

Historians have disagreed on the effects of the Union naval blockade on the states that formed the Confederacy during the United States’ Civil War. This research shows that the Union naval blockade caused a spiraling effect on both the Confederate home front and the Confederate war effort. The Confederacy developed new ordnance factories, machine shops, and sources of essential raw materials such as salt and copper. This growth was not adequate to compensate for the loss of imports from the Union naval blockade. The Confederate government could not meet the needs of its population. Because of the blockade by the …

An Icu-Specific Pressure Injury Risk Assessment Tool To Improve Outcomes, Solange Flore Kamdem

Doctoral Dissertations and Projects

Aim: To use an ICU-specific pressure injury (PI) risk assessment scale to promptly identify the risk for PIs in critically ill patients and promptly implement the appropriate PI prevention interventions to decrease the incidence rate of pressure injuries over 11 weeks.

Background: The risk of developing PIs is 3.8 times higher in the ICU patients than in other patient populations. The state of illness and or treatments increase their odds of developing hospital-acquired pressure injuries (HAPIs). The Braden scale currently in use may not identify the risk early enough to provide preventive interventions. An ICU-specific tool is needed to screen …

Exploration Of How Unified Theory Of Acceptance And Use Of Technology Enhances Trust In Communication, Samantha M. Ricciardi

Doctoral Dissertations and Projects

The qualitative study aims to understand the central phenomenon of how trust enhances communication with online grocery shopping for participants who are 25 years and older and are active online grocery shoppers. Venkatesh, Morris, and Davis created a technology acceptance model called Unified created Theory of Acceptance and Use of Technology, which explains the acceptance and use of information systems and communication technology innovations with consumers (Kim et al., 2008; Phillippi et al., 2021). The Unified Theory of Acceptance and Use of Technology is an alternative theoretical model that ties into eight existing user acceptance models: (a) Technology Acceptance Model …

A Phenomenological Study Exploring The Lived Experiences Of Professionals Supporting Minor-Aged Human Trafficking Survivors In Northeast Nonmetropolitan Communities, Danielle Alexandra Thomas

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the experiences of professionals working with minor-aged survivors of human trafficking in nonmetropolitan environments throughout the Northeast. Husserl's noematic process, integrated with Maslow's theory of human motivation, provided this study's theoretical framework, which strived to answer the fol-lowing research questions: What are the experiences of professionals working with minor-aged human trafficking survivors in Northeast nonmetropolitan communities? and How do professionals describe their experiences helping minor-aged survivors of human trafficking obtain their basic needs after exploitation? Data collection involved demographic questionnaires and inter-views. The data was analyzed by using Moustakas' phenomenological …

The Impact Of Increased Interdisciplinary Communication On Hospital Admission Rates In The Geriatric Population: An Integrative Review, Molly K. Langston

Doctoral Dissertations and Projects

The medical complexity of geriatric residents puts them at an increased risk of hospital readmissions related to coronary artery disease, myocardial infarction, chronic obstructive pulmonary disease, and diabetes, along with other chronic diseases. Geriatric residents of assisted living, skilled nursing, and memory care facilities should hold a particular interest to stakeholders, as the simple intervention of increasing early communication and correspondence regarding chronic diseases can have a great impact on quality improvement outcomes as well as financial burden of the institution. Additionally, interdisciplinary communication can be individualized to meet the needs of each geriatric resident in order to reduce the …

Adiposity, Insulin Resistance, Cardiorespiratory Fitness, And Bone Health In Hispanic Children, Reem S Shawar, Maurice Puyau, Roman Shypailo, Salma Musaad, Nancy F Butte, Fida Bacha

Faculty, Staff and Students Publications

CONTEXT: Childhood obesity disproportionately affects Hispanic youth. The skeletal system appears to be a target organ of the adverse effects of obesity. Yet, the relationship between adiposity and bone health in youth and the modulating factors are not well understood.

OBJECTIVE: This work aims to examine the relationship between adiposity, insulin resistance (IR), cardiorespiratory fitness (CRF), and bone mass in Hispanic youth.

METHODS: A total of 951 Hispanic youth (50% male), aged 4 to 19 years, participated in this cross-sectional design study from the Viva La Familia Study at Children's Nutrition Research Center. Bone mineral content (BMC) and density (BMD), …

A Case Series Of Children With Acute Hepatitis And Human Adenovirus Infection, L Helena Gutierrez Sanchez, Henry Shiau, Julia M Baker, Stephanie Saaybi, Markus Buchfellner, William Britt, Veronica Sanchez, Jennifer L Potter, L Amanda Ingram, David Kelly, Xiaoyan Lu, Stephanie Ayers-Millsap, Wesley G Willeford, Negar Rassaei, Julu Bhatnagar, Hannah Bullock, Sarah Reagan-Steiner, Ali Martin, Michael E Rogers, Anna M Banc-Husu, Sanjiv Harpavat, Daniel H Leung, Elizabeth A Moulton, Daryl M Lamson, Kirsten St George, Aron J Hall, Umesh Parashar, Adam Macneil, Jacqueline E Tate, Hannah L Kirking

Faculty, Staff and Students Publications

BACKGROUND: Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 and early 2022, several previously healthy children were identified with acute hepatitis and human adenovirus viremia.

METHODS: We used International Classification of Diseases, 10th Revision, codes to identify all children (<18 years of age) with hepatitis who were admitted to Children’s of Alabama hospital between October 1, 2021, and February 28, 2022; those with acute hepatitis who also tested positive for human adenovirus by whole-blood quantitative polymerase chain reaction (PCR) were included in our case series. Demographic, clinical, laboratory, and treatment data were obtained from medical records. Residual blood specimens were sent for diagnostic confirmation and human adenovirus typing.

RESULTS: A total of 15 children were identified with acute hepatitis - 6 (40%) who had hepatitis with an identified cause and 9 (60%) who had hepatitis without a known cause. Eight (89%) of the patients with hepatitis of unknown cause tested positive for human adenovirus. These 8 patients plus 1 …

Basic Need Challenges Of Today's Students: How To Best Support These Needs, Mateja Savoie Roskos, Jennifer Grewe, Jess Lucero, Jan Thornton

Empowering Teaching Excellence Conference

College students face a vast array of basic needs challenges that can impact their ability to thrive inside and outside of the classroom. Basic needs can include (but are not limited to) food and housing security, healthcare for mental and physical health/well-being, childcare, resources for personal hygiene, and more. Utah State University has many programs and services that aim to support the basic needs of students. In addition, there are many off campus resources that students are often eligible for. Being aware of the resources available and connecting students to those resources is essential when helping students navigate these hardships. …

Nitric Oxide-Inhibited Chloride Transport In Cortical Thick Ascending Limbs Is Reversed By 8-Iso-Prostaglandin-F2Α, Pablo D. Cabral, Guillermo B. Silva, Sandra T. Baigorria, Luis I. Juncos, Ebenezer I. O Ajayi, Néstor H. García

Hypertension and Vascular Research Articles

Background: Salt reabsorption in the cortical thick ascending limb (cTAL) is regulated by opposing effects. Thus, while nitric oxide (NO) inhibits sodium chloride (NaCl) reabsorption, 8-iso-prostaglandin-F2α (8-iso-PGF2α) stimulates it. Their interaction, however, has not been evaluated in the cTAL. Because 8-iso-PGF2α has considerable stability while NO is a free radical with a short half-life, we hypothesized that, in the cTAL, the inhibition of NaCl absorption will be reversed by 8-iso-PGF2α.

Methods: Chloride absorption (JCl) was measured in isolated perfused cTALs. We also evaluated whether activation of protein kinase A (PKA) is required for this interaction. Since cyclic adenosine monophosphate (cAMP) …

Marine And Not Terrestrial Resources Support Nearshore Food Webs Across A Gradient Of Glacial Watersheds In The Northern Gulf Of Alaska, James W. Schloemer

Marine Biology

Estuaries are among the most productive ecosystems on Earth, yet are especially at risk in high-latitude regions due to climate-driven effects on the connected terrestrial and marine realms. Warming in these regions exceeds the global average and is a major cause of the rapid melting of glaciers. As a result, the timing and magnitude of freshwater discharge into estuaries are subject to increase during the peak in glacial meltwater, ultimately affecting the riverine flux of nutrients and organic matter (OM) from the land to coastal environments. Intertidal communities near the outflow of rivers often rely on supplementing local (marine) food …

The Impact Of Dieting Culture Is Different Between Sexes In Endurance Athletes: A Cross-Sectional Analysis, Austin J. Graybeal, Andreas Kreutzer, Jada L. Willis, Robyn Braun-Trocchio, Kamiah Moss, Meena Shah

Faculty Publications

Background: Frequent dieting is common in athletes attempting to achieve a body composition perceived to improve performance. Excessive dieting may indicate disordered eating (DE) behaviors and can result in clinical eating disorders. However, the current nutrition patterns that underly dieting culture are underexplored in endurance athletes. Therefore, the purpose of this study was to identify the sex differences in nutrition patterns among a group of endurance athletes.

Methods: Two-hundred and thirty-one endurance athletes (females = 124) completed a questionnaire regarding their dieting patterns and associated variables.

Results: The majority of athletes did not follow a planned diet …

Lindenwood Digest, August 17, 2022, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Soundscapes On The Arctic Coastal Plain: Assessing Sound Disturbance And The Auditory Sensitivity Of Caribou (Rangifer Tarandus), Megan E. Perra

Biological Sciences

The Arctic Coastal Plain of Alaska is a region on traditional Inupiat land that supports millions of migratory birds and over half a million caribou (Rangifer tarandus) at the most critical time in their life-histories. They are an important part of seasonal subsistence activities for the surrounding rural Indigenous communities. Therefore, conservation efforts that support this ecosystem also bolster food security in the region. Monitoring this system has increasingly become a necessary and prudent task as the landscape evolves under the pressures of resource extraction and climate change. To date, limited research has been conducted on the sounds present in …