Digital Commons Network^™

Sodium Content Of Packaged Foods And Beverages In Nigeria: A Cross-Sectional Comparative Study With Who Global Sodium Benchmarks, Kenya, And South Africa, Adedayo E Ojo, Alexandra Jones, Kylie Howes, Vanessa Alfa, Anthony Orji, Oluwafemi A Stephen, Carla Pool, Alex Kibet, Fraser Taylor, Diederick E Grobbee, Bruce Neal, Mark D Huffman, Dike B Ojji, Sanne A E Peters

2020-Current year OA Pubs

High intake of processed foods, especially those with high sodium content, is a contributor to hypertension and cardiovascular disease. This study aimed to compare the sodium content of packaged foods and beverages in Nigeria to WHO Global Sodium Benchmarks and similar products in Kenya and South Africa. The study examined packaged foods from major retail stores in the capital cities of the Federal Capital Territory, Kano, and Ogun states in Nigeria from November 2020 to March 2021. Benchmark values were based on the 2021 WHO Global Sodium Benchmarks. We used secondary data from packaged food surveys conducted in South Africa …

Beat-Bk: An Adaptive, Randomized Controlled Trial To Treat Polyomavirus Infections (Bkpyv) In Kidney And Kidney-Pancreas Transplantation Recipients (Beat-Bk) Study Protocol, Ryan Gately, Michael Dymock, Dharshana Sabanayagam, Scott B. Campbell, Jonathan C. Craig, Vikas Dharnidharka, Anna Francis, Jonathan M. Gleadle, Martin Hajek, Sana Hamilton, Martin Howell, Nicole Isbel, Allison Jaure, David W. Johnson, John Kanellis, Karen Keung, Siah Kim, Jen Kok, Dirk R. Kuypers, Nicholas Larkins, Wai H. Lim, Rahul Mainra, Julie A. Marsh, Gabor Mihala, Brian Nankivell, Samantha Ng

Research outputs 2022 to 2026

Background. – BK polyomavirus (BKPyV) is a common opportunistic infection in kidney transplant recipients, typically reactivating in the context of immunosuppression. Although asymptomatic in immunocompetent individuals, reactivation in transplant recipients can cause BKPyV-associated nephropathy (BKPyVAN), a leading cause of graft dysfunction and loss. BKPyV viremia affects approximately 10%–15% of transplant recipients, and once BKPyVAN is established, the risk of graft failure can exceed 50%. The current standard of care involves immunosuppression reduction to restore virus-specific immunity, but this approach increases the risk of acute and chronic rejection. Intravenous immunoglobulin (IVIg), which contains antiviral and immunomodulatory antibodies, has been proposed as …

A Pocket Manual For Human Papillomavirus Vaccines, Natalie A Voss, J Brooks Jackson, Mary B Rysavy

Faculty, Staff and Student Publications

Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and is responsible for the majority of cervical, anal, and vaginal cancers. The first prophylactic HPV vaccine was introduced in the United States in 2006. Extensive evidence demonstrates the HPV vaccine is highly efficacious and effective, particularly when administered prior to HPV exposure. Despite strong safety data and proven cost-effectiveness, HPV vaccine uptake in the United States and globally remains suboptimal. Barriers to vaccination include limited knowledge, safety concerns, and logistical challenges. Current advancements focus on single-dose vaccine regimens, development of therapeutic vaccines, and higher-valent formulations. Expanding HPV vaccine …

Spartan Daily, March 4, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 18

New Records Of The American Bumble Bee, Bombus Pensylvanicus, In Michigan, Sharron Z. Miller, Logan M. Rowe, Lillyanna Widdicombe, Robert P. Jean, Rufus Isaacs

The Great Lakes Entomologist

We report recent detections of the American bumble bee, Bombus pensylvanicus (De Geer) (Hymenoptera: Apidae), in 16 counties of Michigan, USA. This bee species is currently listed as state endangered in Michigan. The current report provides an update on the distribution of B. pensylvanicus in Michigan from collections made between 2020 and 2024, including detections from at least 21 locations in the Lower Peninsula, expanding the known distribution in this state. These samples were from four pollinator survey projects with records from photographs and collections and two online participatory science programs where users uploaded photographs of this species while verified …

Impressions Of An Electrolyte Beverage Among Individuals Participating In Collegiate Sports, S. Andrew Cage, Alexander P. Jacobsen, Jessie Gibson, Eric Bobel, Rebecca Peebles, Derek Lege, M.Ed., Cscs

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this project was to describe the appeal of an electrolyte hydration beverage for individuals participating in collegiate athletics. A secondary purpose of this project was to describe the acute impact of the examined beverage on the gastrointestinal tract. Methods: A total 100 individuals participating in collegiate athletics were enrolled in this study (age = 21 ± 2 years, Male = 51, Female = 49). Each participant was provided a packet of electrolyte drink mix (EverLyte^® sticks, Kent Precision Foods Group, Inc., Muscatine, IA). Participants were instructed to combine the drink mix with a bottle of …

Assessing The Feasibility Of A Virtual Objective Structured Clinical Examination For Medical Education: A Mixed-Methods Study Involving Students And Educators, Jacqueline Segovia, Alejandra Quiroz, Francisco J. Villalon Lopez, Valentina Marican, Marcia Maldonado, Ivonne Moreno, Robinson Torres, Camila Peralta, Ingrid Puchi

Internet Journal of Allied Health Sciences and Practice

Purpose: The COVID-19 pandemic disrupted clinical training and accelerated the adaptation of the Objective Structured Clinical Examination to virtual formats (vOSCEs). Evidence on the feasibility of vOSCEs in undergraduate education remains limited in Latin America. Methods: A quasi-experimental mixed-methods study was conducted with fifth-year medical students at a Chilean university in 2021. Feasibility was assessed using Bowen’s framework—acceptability, implementation, integration, limited-efficacy testing, and adaptation—through online questionnaires and role-segmented focus groups. Two vOSCE iterations combined dynamic stations with simulated patients and static “mailbox” tasks delivered via Zoom and CANVAS. After the first iteration, modifications included a single Zoom session with breakout …

Prevalence And Determinants Of Perceived Stress Among Undergraduate Respiratory Therapy Students In Saudi Arabia, Abdulmajeed A. Baogbah, Ralph D. Zimmerman, Laryssa D. Frederick, Corinne M. Hathaway

Internet Journal of Allied Health Sciences and Practice

Background: Stress is a common phenomenon among health sciences students, severely impacting students in different ways. Similar to other students, undergraduate Respiratory Therapy (RT) students are at a high risk of stress exposure that may harm their well-being. To enhance students’ well-being, it is essential to examine the prevalence and determinants of perceived stress among undergraduate RT students. Methods: A cross-sectional study was conducted during the academic year (2023-2024) to explore the prevalence and determinants of perceived stress. Data was collected through an anonymous self-administered survey consisting of 46 questions, including demographics, the Perceived Stress Scale (PSS-14), and sources of …

Agreement Of Chatgpt With Clinical Practice Guidelines For Knee Osteoarthritis Treatment, Alessandra N. Garcia, Brian Neville, Bradley Myers, Lori Leineke, Karlyn Green

Internet Journal of Allied Health Sciences and Practice

Purpose: This cross-sectional study evaluated whether Chat Generative Pre-Trained Transformer (ChatGPT) GPT-3.5 and GPT-4O provide treatment information consistent with high-quality clinical practice guidelines (CPGs) for knee osteoarthritis (OA). Methods: High-quality CPGs published in the past decade were identified via PubMed and PEDro, with the search updated on November 11, 2024. Guidelines were appraised using the AGREE II tool. GPT-3.5 and GPT-4O were queried with common treatment-related questions, and their responses were compared to CPG recommendations. Two independent reviewers conducted a thematic content analysis of GPT-3.5 and GPT-4O responses using a deductive–inductive codebook, iteratively refined through consensus, to identify major themes/subthemes, …

Health Professional Students' Experiences With Gender-Identity Inclusive Content In The Classroom And Supervised Clinical Learning, Perry Xinyi Zhang, Aria Grabowski, Olivia S. Anderson

Internet Journal of Allied Health Sciences and Practice

Purpose: Gender-identity diverse populations have unique healthcare needs, but they experience stigmatization leading to negative health outcomes. Healthcare professionals have reported obstacles to delivering affirming care to gender-identity diverse patients due to limited training. We assessed how health profession students encounter gender-identity content and how students’ perceived preparedness to provide care for gender-identity diverse populations. Methods: A survey distributed to students enrolled in health professional programs at a large mid-western university included close-ended questions about exposure to gender-identity diverse curricular content in didactic and supervised clinical settings and perceived preparedness to work with gender-identity diverse populations. Open-ended questions asked what …

The Effect Of A Mindfulness-Based Program On Musculoskeletal Pain And Function, Christine Conroy, Kent E. Irwin, Paige Dougherty, Teresa Elliott-Burke

Internet Journal of Allied Health Sciences and Practice

Purpose: Mindfulness-based Stress Reduction (MBSR) is a structured therapeutic tool that was developed in the 1980s by Kabat-Zinn and colleagues. Mindfulness-based interventions (MBIs) have been developed based on the fundamental principles of MBSR and are an emerging area of research. These programs are used to decrease pain levels and kinesiophobia in patients with chronic disease and pain. The purpose of this case study is to describe the effects of MBIs on function and pain for a middle-aged patient, two-month post-proximal humerus fracture. Method: A 53-year-old woman presented status post closed fracture of the proximal right humerus resulting from a …

Exploring Hydration Strategies: A Preliminary Comparison Of Fluid Administration Methods In Collegiate Football Players, Emily E. Lodge, Gillian Romanchok, Isabella M. Farmer, Kimberly Schwabenbauer, Rich Patterson

Internet Journal of Allied Health Sciences and Practice

Introduction: Maintaining optimal hydration is critical for athletic performance and preventing heat-related illness, particularly among football players who face elevated risk due to heavy protective equipment and intense physical demands. As core body temperature and heart rate increases, physiological strain causes are directly correlated with the severity of body water deficit. Dehydration levels exceeding 2% of body weight significantly impair both aerobic performance capacity and cognitive ability. Purpose: Therefore, the purpose of this research is to investigate whether fluid consumption among collegiate football players differs based on administration methods (self-administration versus athletic trainer administration) during practice sessions. Methods: Twenty male …

Improved Process For The Preparation Of Calcium Gluconate By Phase Transfer Catalysis, Anonymous

Defensive Publications Series

Calcium gluconate is an essential pharmaceutical and nutritional compound, widely employed as a calcium supplement and therapeutic agent. Conventional aqueous synthesis methods, while effective, often suffer from kinetic inefficiencies and purification challenges. Phase transfer catalysis (PTC) offers a promising alternative by enabling ionic substrates to cross phase boundaries, thereby enhancing reaction rates and selectivity. Building on CN110256234B, which demonstrates the use of selected quaternary ammonium salts, this work discloses an expanded spectrum of PTCs applicable to calcium gluconate synthesis. The improved process achieves higher efficiency, reproducibility, and product purity.

Enhancing Village Health Volunteers' Capacity In Health Promotion For Ncd Risk Groups Via Digital Technology: An Action Research Study In Sing Buri, Thailand¬, Worayuth Nak-Ai, Ngamjit Phranetr, Phatt Thaitrong, Uten Sutin, Pinkamon Sompeewong

Journal of Health Research

Background: Non-communicable diseases (NCDs) pose a major public health challenge in Sing Buri Province, Thailand. This action research examined the effectiveness of digital health communication innovations delivered through Village Health Volunteers (VHVs) to support NCDs management among at-risk populations.

Methods: Employing the Plan-Act-Observe-Reflect cycle (PAOR), the study engaged 8 VHVs, 40 at-risk individuals, and 6 public health officers at Pikhun Thong Health Promotion Hospital, Sing Buri Province from February to September 2024. Digital interventions included pedometer apps, LINE-based dietary tracking, and peer learning groups with competitions and rewards. Quantitative data were analyzed using z-tests and Wilcoxon signed-rank tests, while …

Results Of A Phase Ii Open-Label, Multiple-Dose Study Of Vamorolone (Vbp15-006) In 7- To < 18-Year-Old Boys With Duchenne Muscular Dystrophy, Hanns Lochmüller, Hernan Gonorazky, Elisa Nigro, Jean K. Mah, Alberto Alemán, Amanda Yaworski, Maryam Oskoui, Anne Marie Sbrocchi, Kathryn Selby, Ana De Vera, Laura Mcadam, Ekaterina Gresko, Aki Linden, Catherine Dutreix, Eric P. Hoffman

Pharmacy Faculty Scholarship

Background: Vamorolone is a dissociative glucocorticoid receptor agonist for treating Duchenne muscular dystrophy (DMD). The VBP15-006 study assessed vamorolone safety, tolerability, and pharmacokinetics in 2- to < 4 and 7- to < 18-year-old boys with DMD. Results for 7- to < 18-year-old boys, either corticosteroid (CS)-untreated or switching from prior CS treatment, are reported here. Exploratory objectives included efficacy and pharmacodynamic biomarkers related to safety. Methods: In this phase II, open-label, multiple-dose study, participants received 2 or 6 mg/kg/day vamorolone for 12 weeks, followed by treatment in an expanded access protocol (EAP Canada). Results: 34 participants (12 CS-untreated, 22 CS-treated) aged 7- to < 18 years were enrolled. Most treatment-emergent adverse events were mild. All 34 participants completed VBP15-006 and entered EAP Canada. During EAP Canada, CS-untreated participants maintained stable linear growth, while CS-treated participants exhibited catch-up growth consistent with serum bone biomarkers (median total vamorolone exposure 1.3 and 1.7 years, respectively). Some weight gain occurred, especially in CS-untreated participants receiving 6 mg/kg/day. Dose-dependent adrenal suppression occurred in CS-untreated and CS-treated participants; 2 individuals who switched from deflazacort to vamorolone 2 mg/kg/day had generalized weakness consistent with adrenal insufficiency. Vamorolone showed dose-dependent pharmacokinetics, rapid clearance, and no accumulation. There were no relevant efficacy changes in CS-treated and CS-untreated groups at either dose. Conclusions: Vamorolone demonstrated a consistent safety profile in 7- to < 18-year-old boys with DMD. Switching to 6 mg/kg/day vamorolone appeared to mitigate adrenal insufficiency risk. There was no negative effect on growth, and catch-up growth occurred in previously CS-treated individuals switching to vamorolone. Trial registration: ClinicalTrials.gov: NCT05185622, NCT03863119. First submitted 09-11-2021.

March 3, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Muscular Fitness Levels Of U.S. Children And Adolescents, Daniel J. Mcdonough, Yong Gao, Lynda B. Ransdell, Haichun Sun

International Journal of Physical Activity and Health

Purpose: To describe muscular fitness (MF) levels and percentile benchmarks among U.S. children and adolescents aged 6–15 years old across sociodemographic, physiological, and behavioral subgroups. Methods: Data were from the 2012 NHANES National Youth Fitness Survey (NNYFS). Four strength tests consisting of the plank, knee extension, modified pull-up, and handgrip, were analyzed by age, sex, race/ethnicity, income, BMI category, cardiorespiratory fitness (CRF), and physical activity (PA) among 1,234 participants (51% male) using SAS SURVEY procedures. Results: Mean ± SEM scores were 69.6 ± 1.8 s (plank), 56.6 ± 4.2 lb (left) and 59.2 ± 4.3 lb (right) knee extension, 5.5 …

Post-Traumatic Stress Disorder And Risk Of All-Cause And Cause-Specific Mortality: A Nationwide Population And Sibling-Controlled Cohort Study In Taiwan, Chih-Wei Hsu, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Aims: Post-traumatic stress disorder (PTSD) may shorten life expectancy, but evidence for Asian populations and cause-specific mortality remains limited. The aim of this study is to investigate the association between PTSD and mortality risk in an Asian population.

Methods: We used Taiwan's National Health Insurance Research Database (2000-2022) to assemble a cohort of 28,777 individuals with incident PTSD and 115,108 age- and sex-matched unexposed individuals, plus a sibling cohort of 13,305 affected patients and 22,030 unaffected siblings. Cox models estimated adjusted hazard ratios (AHRs) for all-cause, unnatural-cause (suicide and accidents) and natural-cause mortality, with progressive adjustment for sociodemographic factors, comorbidity …

Physical And Chemical Study Of Interaction In The Urea–Valine System For The Creation Of Modified Liquid Nitrogen Fertilizers, Suvonkul Erkhanovich Nurmonov, Saydullo Khamidovich Azimov

Chemical Technology, Control and Management

This study reports the results of a comprehensive physicochemical investigation of the urea–L-valine binary system, conducted to validate its potential as a modified base for liquid nitrogen fertilizers.

By utilizing the methods of isomolar series, visual-polythermal analysis, X-ray phase (XRD) and single-crystal X-ray diffraction (SC-XRD), synchronous thermal analysis (TGA/DTA), and FT-IR spectroscopy, it was determined that the interaction between components in both aqueous solutions and the solid phase results in the formation of molecular associates stabilized by hydrogen bonds, without the formation of new stoichiometric compounds.

The concentration and temperature limits of the system's stability were defined, revealing a reduction …

Circulating Ketone Bodies And Incident Cardiovascular Outcomes And Mortality: Insights From The Uk Biobank, Parag Anilkumar Chevli, Saeid Mirzai, Richard Kazibwe, Jeff Kingsley, Alexis C Wood, Joseph Yeboah, Leandro Slipczuk, Anurag Mehta, Harpreet S Bhatia, Ambarish Pandey, Michael D Shapiro

Children’s Nutrition Research Center Staff Publications

Background: Ketone bodies (KB) are endogenous energy sources synthesized by the liver in response to metabolic stress. Their associations with atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), and mortality and their potential beneficial or harmful effects have yet to be determined. This study aimed to examine the association between KB and incident cardiovascular outcomes and mortality in a large general population cohort free from ASCVD and HF at baseline.

Methods: This analysis included 90 987 participants (mean age 56.4 ± 8.1 years; 54.7% women) from the UK Biobank without prevalent ASCVD or HF. KB were measured by nuclear magnetic resonance …

Assessment And Surface Modeling Of Cod Removal From Simulated Dairy Wastewater In A Continuous Advanced Oxidation Reactor, Anwar Hashim, Mohammed Salman

Engineering and Technology Journal

The paper herein shows modeling and optimization of a continuous-flow ultraviolet/hydrogen peroxide (UV/H2O2) AOP to degrade chemical oxygen demand (COD) in simulated dairy wastewater. The common conventional treatment procedures, such as biological and physicochemical processes, may be limited by the high amount of sludge formation, high costs, and poor removal of recalcitrant organic contaminants that form. This research, therefore, aims to design a more effective photochemical treatment alternative by conducting experimental studies and developing a more accurate model. A tailor-made cubic photoreactor with double 6 W low-pressure UV lamps (254 nm) was used to investigate the effect of three parameters: …

What Do Future Nutrition Professionals Think About Wic Jobs? A Study Of Nutrition Career Perceptions, Madison Degenfelder

Theses

Background: The Special Supplemental Nutrition Program for Women, Infants and Children (WIC) program faces a critical workforce shortage, yet little is known about the knowledge, attitudes, and beliefs of nutrition students and recent graduates regarding WIC career pathways, requirements, and compensation. Understanding these factors is essential to design strategies to strengthen recruitment and build a sustainable WIC workforce. Objective: To identify and describe knowledge, attitudes and beliefs on entering the WIC workforce among college nutrition and dietetics students and recent graduates. Design: A mixed-methods, sequential study design which included a cross-sectional survey and two focus groups was employed to ascertain …

Surgical Removal Of Visceral Adipose Tissue Has Therapeutic Benefit In Male Appnl-F Mice, Samuel A. Mcfadden, Yimin Fang, Kathleen Quinn, Mackenzie R. Peck, Jenelle E. Chapman, Tiarra Hill, Andrzej Bartke, Erin R. Hascup, Kevin Hascup

Articles

Purpose:  Visceral white adipose tissue (vWAT) accumulation causes systemic inflammation, insulin resistance, metabolic syndrome, and senescent cell accumulation that are risk factors for Alzheimer’s disease (AD). Visceral fat removal (VFR) improves metabolism and reduces pro-inflammatory cytokines.  We hypothesized that VFR removal in AD mice would improve metabolism and cognition.

Methods:  Male and female APP^NL-F mice underwent sham or vWAT surgical resection (periovarian or epididymal and perirenal) at 4 (pre-symptomatic) and 16 (symptomatic) months of age to understand interventional and therapeutic effects, respectively.  At 18 months of age, glucose metabolism and novel object recognition (NOR) memory were assayed followed by …

Force–Power Profiles And Countermovement Utilization Ratios In U.S. Ski & Snowboard National Team Athletes, Joshua Bullock

Doctorate in Kinesiology

Mogul skiing imposes high neuromuscular and lower-extremity loading athlete demands, yet mogul-specific reference values for jump-derived force–power characteristics and differential utilization metrics have remained limited. The specific aims of this study were to: 1) establish descriptive statistics, including means, percentiles, and variability for jump height (JH), peak force (PF), and peak power (PP) during the squat jump (SJ) and countermovement jump (CMJ) in elite mogul skiers, 2) determine corresponding countermovement utilization ratio (CUR) values for each measure (JH-CUR, PF-CUR, and PP-CUR), and 3) report descriptive outcomes independently for both male and female athletes to provide sex-specific reference profiles. Archived testing …

Shiga Toxin-Producing Escherichia Coli Outbreak In Canadian Daycare Centers, Mohamed Eltorki, Oluwatimilehin O Ajayi, Jina Seok, Jianling Xie, Francesco A Rizzuti, Byron M Berenger, Phillip I Tarr, Andrew T Pavia, Kate Snedeker, Silviu Grisaru, Otto G Vanderkooi, Linda Chui, Gillian A M Tarr, Gemma Vomiero, Stephen B Freedman

2020-Current year OA Pubs

IMPORTANCE: Shiga toxin-producing Escherichia coli (STEC) infections have significant morbidity, with 15% to 20% of children developing hemolytic uremic syndrome (HUS), more than half of whom require kidney replacement therapy (KRT).

OBJECTIVE: To describe health care resource utilization, clinical outcomes, and outcomes associated with daily laboratory monitoring for thrombotic microangiopathy (TMA) in a large point-source STEC outbreak.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study was conducted among a population-based cohort of individuals exposed to a contaminated food item served in 11 childcare centers in Calgary, Alberta, Canada, on August 29, 2023. Children and adults with confirmed STEC infection linked …

The Echo: March 2, 2026, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Jackfruit Peel Valorization Through An Integrated Biorefinery Approach, Rohil Kumar K Mr

Theses and Dissertations

Jackfruit (Artocarpus heterophyllus) peel (JFP), an abundantly available lignocellulosic biomass, remains largely underutilized despite being rich in cellulose, hemicellulose, lignin, and pectin. In India, approximately 13,460 hectares are under jackfruit cultivation, with Panruti in Tamil Nadu as a major production zone. The discarded peel often contributes to environmental pollution and greenhouse gas emissions. The present study emphasizes sustainable valorization of JFP through an integrated biorefinery framework for generating value-added bioproducts.

Major biopolymers, cellulose, hemicellulose, lignin, and pectin were extracted and fractionated, followed by detailed physicochemical characterization using FTIR, NMR, XRD, SEM, TGA, DSC, GPC, and BET analyses. Pectin extraction with …

Cultivation Of Arthrospira Platensis (Spirulina) In Food-Based Industrial Wastewater For High-Yield Phycocyanin Extraction, Pavithira Sathinathan

Student Works (2020-2029)

Arthrospira platensis (Spirulina) is a filamentous cyanobacterium valued for its nutritional profile, particularly the pigment–protein phycocyanin, with potent antioxidant and anti-inflammatory properties. Despite its industrial significance, large-scale commercialization remains constrained by high cultivation costs and inefficient extraction methods. This study investigated the use of food-based industrial wastewater as an alternative nutrient medium for Spirulina cultivation, aiming to reduce production costs, enhance phycocyanin yield, and support sustainable wastewater remediation. Three types of food-based wastewater with different nutrient composition (WW1, WW2, WW3) was diluted with Kosaric medium (1:1) and used for Spirulina cultivation. The highest biomass concentration was achieved in WW2 (1.93 …

Colocalization And Functional Analyses Identify Gbe1 As A Gene Linking Muscle Strength And Cardiometabolic Fitness, Theresia M. Schnurr, Miranda L. Johnson, Christopher Jin, Kimmie V. Sørensen, Lindsey Kim, James W. Jahng, Amanda Ramste, Ewa Bielczyk-Maczynska, Michael J. Gloudemans, Peter Saliba-Gustafsson, Elena Vinton, Patrick L. Jurney, Ivan Carcamo-Orive, Euan A. Ashley, Torben Hansen, Joshua W. Knowles, Brian T. Palmisano

Faculty Research, Scholarly, and Creative Activity

Handgrip strength is a proxy for muscular fitness, an indicator for general health status, and is associated with cardiometabolic health. The mechanisms connecting handgrip strength to skeletal muscle function are incompletely understood. We applied integrated linkage-disequilibrium-adjusted colocalization analysis of genome-wide association study summary statistics for handgrip strength, combined with expression and splicing quantitative trait loci from skeletal muscle, and identified glycogen branching enzyme 1 (GBE1) as a candidate gene for handgrip strength. CRISPR-interference knockdown of GBE1 in immortalized human skeletal muscle cells (HMCL-7304) demonstrated decreased glycogen content and accumulation of polyglucosan bodies. Knockdown of GBE1 led to increased oxygen consumption …

Editorial: Clinical Imaging, Neurophysiological, Neuropathology And Neuroethics Studies On Disorders Of Consciousness, Coma Mechanisms, And Theories Of Consciousness: A Unifying Attempt, Diego Iacono, Manuel Trachsel, Thanh Phan, Charlène Aubinet

Department of Neurology Faculty Papers

No abstract provided.