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Best Practice Occupational Therapy Interventions For Addressing Trauma And Posttraumatic Stress Disorder: A Practitioner Guide, Madison Kay Ertelt Jan 2023

Best Practice Occupational Therapy Interventions For Addressing Trauma And Posttraumatic Stress Disorder: A Practitioner Guide, Madison Kay Ertelt

Occupational Therapy Capstones

Posttraumatic stress disorder (PTSD) impacts approximately 3.6% of adults and 5% of adolescents in the United States and has pervasive impacts on occupational performance (National Institute of Mental Health, n.d.). Occupational therapy practitioners (OTPs) likely encounter clients with PTSD frequently due to this widespread prevalence in addition to trauma being comorbid with a variety of mental and physical health conditions. Despite the widespread prevalence of trauma, many OTPs find that trauma-informed care is not adequately implemented in practice (Holman et al., 2022). There is a gap in the literature regarding occupational performance deficits experienced among clients with trauma, knowledge of …


Assisting Mothers In The Transition Into Motherhood, Abbey Mckenna Marinucci Jan 2023

Assisting Mothers In The Transition Into Motherhood, Abbey Mckenna Marinucci

Occupational Therapy Capstones

The perinatal period ranges from 22 weeks gestation to 2 years postpartum (Hoekzema et al., 2017; Seth et al., 2016; World Health Organization, n.d.). During the perinatal period, intervention is primarily provided by an obstetrician and gynecologist (OBGYN) during pregnancy. Typically, mothers are discharged on average 2.1 days after a natural birth (Podulka et al., 2011). Women are seen at 6 weeks postpartum where mothers’ physical health is the focus of the visit, leaving mothers' mental health concerns unaddressed and questions typically unanswered (American Academy of Pediatrics, 2012 & American College of Obstetricians and Gynecologists, 2012 as cited in Corrigan …


Occupational Therpay’S Role When Treating Pediatric Feeding Disorders, Callie Vold Jan 2023

Occupational Therpay’S Role When Treating Pediatric Feeding Disorders, Callie Vold

Occupational Therapy Capstones

Feeding and eating are required occupations that all humans must engage in to meet one of their most basic needs (AOTA, 2020; Maslow, 1943). While feeding and eating allows humans to meet their most basic physiological needs it also allows them to meet other needs of Maslow's Hierarchy along with engaging in valued occupations (AOTA, 2020; Maslow, 1943. Children with Pediatric Feeding Disorders (PFD) have difficulty with one or more areas of feeding which are medical, nutritional, feeding skill and/or psychosocial dysfunction (Fleet et al., 2022; Goday et al., 2019; Howe & Wang, 2013; Marshall et al., 2015; Sharp et …


Environmental Policy Implementation And Electoral Institutions In Germany And Japan, Kaia Rendo Jan 2023

Environmental Policy Implementation And Electoral Institutions In Germany And Japan, Kaia Rendo

Honors Theses

In an era when attention to reconstruction and preservation of the environment is crucial, this thesis looks at the effect that electoral institutions have on attention paid to the environmental policy issue dimension. Specifically, it looks at party manifestos and policies in post-1980 Germany and Japan to determine if specific electoral structures, such as the number of parties in a system, correlates with a greater amount of either attention paid to environmental policy in party platforms or in the actual passing of policy. It finds that though both Germany and Japan employ multi-member proportional systems, the greater number of parties …


Ghana Dier: An Analysis Of How Availability And Access Impact Food Security In Ghana, Aishat Doyinsola Jimoh Jan 2023

Ghana Dier: An Analysis Of How Availability And Access Impact Food Security In Ghana, Aishat Doyinsola Jimoh

CMC Senior Theses

This paper examines the different causes of food insecurity, the solutions for them, and how Ghana sits on the scale of global food insecurity. Ghana is located in Africa, where food insecurity is the highest in the world, so it would be reasonable to expect food insecurity to be high in Ghana, too. In comparison to its neighboring countries, Ghana has the best food security, standing at number three in sub-Saharan Africa. This paper uses data to examine how Ghana has been this successful. Foundational frameworks in Ghanaian history developed the southern urban parts of Ghana, improving food security in …


India’S Use Of Public/Private Partnerships To Promote Rapid Expansion Of Solar Electricity Facilities, Kara Consalo Jan 2023

India’S Use Of Public/Private Partnerships To Promote Rapid Expansion Of Solar Electricity Facilities, Kara Consalo

Journal Publications

This Article will explore the use of PPPs to encourage the flow of private capital and expertise toward development of low-carbon, low pollution, sustainable energy generation in India to achieve the country's ambitious goal of creating 175 gigawatts of renewably sourced electricity by 2022. The lessons in India's extensive use of PPPs to achieve such ambitious electricity goals should serve as a model for other governments to engage the private sector to successfully develop solar and other renewable energy projects with limited risk but with significant benefits for their citizens.


A Psychological Skills Handbook For Competitive Anxiety In Gymnasts, Kayla Bates Jan 2023

A Psychological Skills Handbook For Competitive Anxiety In Gymnasts, Kayla Bates

Master of Education in Applied Human Development Graduate Projects

The relationship between competitive anxiety and performance has been explained by many authors and researchers. Competitive anxiety can have either a negative or positive effect on performance depending on the athlete’s interpretation of their symptoms. Specifically, the Cusp Catastrophe Model aimed to explain the relationship between physiological arousal and cognitive anxiety, and how these two factors affect performance. Psychological skills training may be used to help train the mind of athletes to decrease competitive anxiety levels and/or reinterpret anxiety symptoms to enhance performance. Gymnastics is a high-skill sport that puts a great amount of stress on the mind and body …


Emerging Applications Of 3d Engineered Constructs From Plant Seed Extracts, Sedat Odabaş, Bora Gari̇pcan, Rihab Ksouri Jan 2023

Emerging Applications Of 3d Engineered Constructs From Plant Seed Extracts, Sedat Odabaş, Bora Gari̇pcan, Rihab Ksouri

Turkish Journal of Biology

Seeds, by-products derived from various plants such as mango, quince, and apples, are considered waste, though they have emerging commercial potential, and have been used in biological, industrial, and physiological research. Seed-derived natural macromolecules- mainly polysaccharides, mucilage, gums, and cellulose-have physicochemical and structural diversification, giving the potential for forming gels, texturing, thickening, and providing interfacial adsorption. Seed-derived natural macromolecules have been widely used during the last few years in cell research and tissue engineering applications. Their widespread approachability and safety, high rate of biodegradability, biocompatibility, supporting cell proliferation, and extracellular matrix synthesis are the main properties making plant seed derivatives …


Association Of Dietary Zinc Consumption With Periodontitis In Diabetes Mellitus Patients: A Cross-Sectional Study Of National Health And Nutrition Examination Surveys Database (2009–2014), Mingdi Xiang, Zhiwen Pan, Siqian Hong, Guifen Cao, Bin Feng Jan 2023

Association Of Dietary Zinc Consumption With Periodontitis In Diabetes Mellitus Patients: A Cross-Sectional Study Of National Health And Nutrition Examination Surveys Database (2009–2014), Mingdi Xiang, Zhiwen Pan, Siqian Hong, Guifen Cao, Bin Feng

Journal of Dental Sciences

Abstract Background/purpose Periodontitis is an independent risk factor for diabetes mellitus (DM), and DM patients had an increased risk in susceptibility to periodontitis. And serum zinc (Zn) levels were low in patients with periodontitis combined with DM. Herein, this study aimed to explore the association between dietary Zn intake and the risk of periodontitis in DM patients, in order to provide some scientific references for the prevention and treatment for periodontitis clinically. Materials and methods Demographic and clinical data of DM patients were extracted from the National Health and Nutrition Examination Surveys (NHANES) database in 2009–2014 in this cross-sectional study. …


A Comparative Profile Of Certain Biochemical And Hematological Parameters In Angora And Akkeçi Goats During The Transition Period, Rabi̇a Aktaş, Erkan Pehli̇van Jan 2023

A Comparative Profile Of Certain Biochemical And Hematological Parameters In Angora And Akkeçi Goats During The Transition Period, Rabi̇a Aktaş, Erkan Pehli̇van

Turkish Journal of Veterinary & Animal Sciences

This study investigated the comparative changes in hematological and certain biochemical parameters such as glucose, cholesterol, triglyceride calcium, phosphorus and total protein during the transition period in Angora and Akkeçi goats aged 2-4 years. For this purpose, blood samples were regularly taken from the vena jugularis of each goat at 3, 2, and 1 weeks before kidding (-3, -2 and -1), on the day of parturition (0) and 1, 2, and 3 weeks after kidding (+1, +2 and +3). According to the statistical analysis results, the differences between the averages of the groups in terms of MCHC, MCH, Lym, THR, …


Serum Trace Element Levels In Dogs With Canine Visceral Leishmaniasis, Aycan Nuri̇ye Gazyağci, Bengü Bi̇lgi̇ç, Berna Baysal Bakay, Duygu Tarhan, Alev Meltem Ercan, Songül Erdoğan, Hasan Erdoğan, Mehmet Erman Or, Kerem Ural Jan 2023

Serum Trace Element Levels In Dogs With Canine Visceral Leishmaniasis, Aycan Nuri̇ye Gazyağci, Bengü Bi̇lgi̇ç, Berna Baysal Bakay, Duygu Tarhan, Alev Meltem Ercan, Songül Erdoğan, Hasan Erdoğan, Mehmet Erman Or, Kerem Ural

Turkish Journal of Veterinary & Animal Sciences

Canine visceral leishmaniasis has been denoted as neglected despite being a very well-known disease. Trace element alteration has been recognized in humans with visceral and cutaneous leishmaniasis, together with canine visceral leishmaniasis. The trace elements occupy a vital position in the immunological system, and host immune responses mitigate defense against leishmaniasis. We aimed to select trace elements in a total of 45 dogs of several breeds; those at the age of 11 months to 6 and from both sexes (26 male and 19 female) were enrolled in the study. The dogs included in the study were divided into leishmaniasis-infected and …


Does Apocynin Increase Liver Regeneration In The Partial Hepatectomy Model?, Yilmaz Bi̇lgi̇ç, Burhan Hakan Kanat, Onural Özhan, Azi̇be Yildiz, Zeynep Aksungur, Mehmet Erman Erdemli̇, Ni̇gar Vardi, Yusuf Türköz, Ahmet Sami̇ Akbulut, Adem Köse, Hakan Parlakpinar Jan 2023

Does Apocynin Increase Liver Regeneration In The Partial Hepatectomy Model?, Yilmaz Bi̇lgi̇ç, Burhan Hakan Kanat, Onural Özhan, Azi̇be Yildiz, Zeynep Aksungur, Mehmet Erman Erdemli̇, Ni̇gar Vardi, Yusuf Türköz, Ahmet Sami̇ Akbulut, Adem Köse, Hakan Parlakpinar

Turkish Journal of Medical Sciences

Background/aim: Hepayocyte loss may develop secondary to liver surgery and at this point liver regeneration plays a significant act in terms of liver reserve. The purpose of this research was to investigate the efficacy of apocynin on liver regeneration and preservation after partial hepatectomy in rats. Materials and methods: A total of 32 rats, have been divided into 4 groups (n: 8) for hepatectomy model. Inflammatory and antiinflammatory parameters were measured from blood and liver tissue samples. In addition, the effects of apocynin were examined immunohistochemically and histopathologically from liver tissue. Results: In liver tissue samples, a significant difference has …


Investigation Of Igf-1, Igf-Bp3 And Igf-Bp5 Levels In Umbilical Cord Blood Of Infants With Developmental Dysplasia Of The Hip, Esra Demi̇rel, Eyüp Şenocak, Gamze Nur Ci̇mi̇lli̇ Şenocak, Ali̇ Şahi̇n, Berri̇n Göktuğ Kadioğlu, Özlem Gündüz Jan 2023

Investigation Of Igf-1, Igf-Bp3 And Igf-Bp5 Levels In Umbilical Cord Blood Of Infants With Developmental Dysplasia Of The Hip, Esra Demi̇rel, Eyüp Şenocak, Gamze Nur Ci̇mi̇lli̇ Şenocak, Ali̇ Şahi̇n, Berri̇n Göktuğ Kadioğlu, Özlem Gündüz

Turkish Journal of Medical Sciences

Background/aim: IGF-1 (insulin-like growth factor-1) is an important regulator of bone formation. Its deficiency has been associated with fetal growth disorders and hip dysplasia. The aim of this study was to evaluate whether IGF-1, IGF-BP3 (insulin like growth factorbinding protein 3), and IGF-BP5 levels in the umbilical cord blood can be predictive for early diagnosis of DDH. Materials and methods: Umbilical cord blood samples were collected from 860 mothers with pregnancies at high risk for DDH between October 2020 and January 2021. Mothers at 37-42 weeks of gestation, with risk factors for DDH, who delivered healthy infants were included. Blood …


The Impact Of Universal Free Meals During Covid-19 On Family Life And Perspective Of School Meals In Central Washington State, Charlotte Green Jan 2023

The Impact Of Universal Free Meals During Covid-19 On Family Life And Perspective Of School Meals In Central Washington State, Charlotte Green

All Master's Theses

This study explored the impact of the USDA COVID-19 Universal Free Meal (UFM) waivers on family life, school meal participation, and child eating habits from parents with children in Central Washington state (WA) schools. n = 119 parents/caregivers with students who were in K-12th grade in Central WA from August 2019-February 2023 completed a 10 question electronic, and descriptive survey. The survey measured changes in participation in school lunch/breakfast pre to post COVID-19 waiver, which provided free meals for all children, and whether UFM were beneficial to families, impacted perception of school food, child’s sense of community at school …


Trademark Counterfeiting Enforcement Beyond Borders: The Complexities Of Enforcing Trademark Rights Extraterritorially In A Global Marketplace With Territorial-Based Enforcement, Kari Kammel, Matthew Azim-Kramer, Daniel Duquet, Lillie Patterson Jan 2023

Trademark Counterfeiting Enforcement Beyond Borders: The Complexities Of Enforcing Trademark Rights Extraterritorially In A Global Marketplace With Territorial-Based Enforcement, Kari Kammel, Matthew Azim-Kramer, Daniel Duquet, Lillie Patterson

Fordham Intellectual Property, Media and Entertainment Law Journal

We focus on the enforcement of trademark rights, particularly those used against counterfeiters, or those who use unauthorized trademarks of another. We examine the concept of extraterritorial enforcement of trademark rights—the extending of enforcement across national borders—and reviewing how different countries and jurisdictions view this concept or even allow it.


From Drawstring To Drawback: A Proposal For The Donation Alternative Program To Promote Environmental Responsibility In Fashion Act, Elliot O. Jackson Jan 2023

From Drawstring To Drawback: A Proposal For The Donation Alternative Program To Promote Environmental Responsibility In Fashion Act, Elliot O. Jackson

Fordham Intellectual Property, Media and Entertainment Law Journal

Given the modern interest in resold, repurposed, upcycled, and thrifted goods, the fashion industry was forced to welcome new players into its global market. In turn, these players offer new meaning to the phrase: “one man’s trash is another man’s treasure,” especially in light of post-pandemic consumer relations. Pairing creativity and innovation with existing techniques has allowed many designers, ateliers, and skilled professionals across the world to transform old or mundane goods into vibrant apparel. A worthy example of this practice is Dapper Dan’s transformation of garment bags from a high-fashion brand into upcycled or repurposed, one-of-a-kind products. The origin …


2023-2024 Graduate Bulletin, Rochester Institute Of Technology Jan 2023

2023-2024 Graduate Bulletin, Rochester Institute Of Technology

RIT Digital Archives

No abstract provided.


Contributions To Professional School Counselors Entering And Remaining In The Profession: A Grounded Theory, Kathryn Babb Jan 2023

Contributions To Professional School Counselors Entering And Remaining In The Profession: A Grounded Theory, Kathryn Babb

Electronic Theses and Dissertations, 2020-2023

As the mental health needs of children and adolescents have reached a crisis level, the need for trained mental health professionals in the field is as important as ever. However, many states are currently experiencing a shortage of educators, including school counselors. Therefore, the purpose of this study is to understand the factors that contribute to school counselors selecting their career, as well as understanding what elements lead to the retention of professional school counselors. As there are no existing theories related to understanding the career choice of professional school counselors, nor pertaining to the supports leading to the retention …


River Report. State Of Lower St. Johns River Basin, Florida: Water Quality, Fisheries, Aquatic Life, Contaminants, 2023, Environmental Protection Board, Jacksonville Florida, University Of North Florida, Jacksonville University, Gerry Pinto, Brian P. Zoellner, Christopher Baynard, Gretchen Bielmyer-Fraser, Dale Casamatta, Charles Closmann, Nisse Goldberg, Ashley Johnson, Scott Jones, William Penwell, Radha Pyati, Adam Rosenblatt Jan 2023

River Report. State Of Lower St. Johns River Basin, Florida: Water Quality, Fisheries, Aquatic Life, Contaminants, 2023, Environmental Protection Board, Jacksonville Florida, University Of North Florida, Jacksonville University, Gerry Pinto, Brian P. Zoellner, Christopher Baynard, Gretchen Bielmyer-Fraser, Dale Casamatta, Charles Closmann, Nisse Goldberg, Ashley Johnson, Scott Jones, William Penwell, Radha Pyati, Adam Rosenblatt

State of the River Report

No abstract provided.


Associations Between Stress, Intuitive Eating, And Adiposity In A Cohort Of Midlife Women, Bridget A. Owens Jan 2023

Associations Between Stress, Intuitive Eating, And Adiposity In A Cohort Of Midlife Women, Bridget A. Owens

Open Access Dissertations

Stress and eating behaviors can influence the health of midlife women, a population at risk for weight gain and redistribution of fat to the abdominal area related to shifts in reproductive hormones and aging. Higher stress is associated with negative health outcomes such as increased abdominal adiposity, depression, and chronic diseases such as cardiovascular disease. Women report higher stress and more emotional and physical side effects from stress than men and are more likely than men to engage in emotional eating in response to stress. Further, the desire to lose weight and the prevalence of body dissatisfaction is high among …


Heparin Vs. Saline: Evaluating Evidence-Based Best Practice For Maintaining Patency Of Implanted Ports, Shannon D. Murdock Jan 2023

Heparin Vs. Saline: Evaluating Evidence-Based Best Practice For Maintaining Patency Of Implanted Ports, Shannon D. Murdock

Master's Theses and Capstones

Background Implanted ports are frequently used for central venous access in the adult oncology population. Maintaining patency of these ports is important for continuing uninterrupted treatment and supportive care for oncologic patients. Historically, heparin solution has been used as a locking solution for implanted ports to prevent occlusion. However, evidence shows that 0.9% sodium chloride (normal saline or NS) as a lock solution is equally effective as heparin solution at maintaining implanted port patency and poses less risk to patients.

Local Problem In an ambulatory adult oncology clinic serving Seacoast New Hampshire, a gap was identified between clinical practice where …


Child Pain Matters: A Training Protocol For General Nursing Staff In An Infusion Center On Procedural Anxiety In Pediatric Patients With Crohn's Disease And Ulcerative Colitis., Mera El Ramahi Jan 2023

Child Pain Matters: A Training Protocol For General Nursing Staff In An Infusion Center On Procedural Anxiety In Pediatric Patients With Crohn's Disease And Ulcerative Colitis., Mera El Ramahi

Psychology Doctoral Specialization Projects

Procedural anxiety is a broad concept that encompasses fear, distress, and pain. Anxiety is the most critical factor affecting pain perception. There is a growing body of literature suggesting that early pain might have long-term consequences. There is also research evidence that has linked inadequately managed pain in the pediatric population to negative behavioral and physiological consequences later in life. Pediatric patients with inflammatory bowel disease (IBD) refers to Crohn’s disease and Ulcerative Colitis. These chronic conditions often require multiple and repeated medical procedures that may cause pediatric patients to experience procedural anxiety. Needle related procedures are any procedures involving …


Ascophyllum Nodosum Seaweed Extract Application As A Possible Mechanism For Mitigating Salt Stress In Soybeans (Glycine Max), Elena Hoang Jan 2023

Ascophyllum Nodosum Seaweed Extract Application As A Possible Mechanism For Mitigating Salt Stress In Soybeans (Glycine Max), Elena Hoang

Honors Program Theses

Soil salinity, an abiotic stressor associated with climate change effects, inhibits the normal growth and development of sensitive crop species. The excessive accumulation of salt ions in plant tissue induces oxidative stress, which is characterized by an increased production of reactive oxygen species (ROS) damaging plant organelles and disrupting normal metabolic functions. Seaweed extracts (SWE) may be a solution for mitigating the effects of salt stress on crop yield and quality, as they introduce bioactive ingredients that are able to regulate gene expression and enhance natural physiological processes in plants. However, the positive benefits of SWE applications differ between plant …


Producing Grnas For Use In Crispr-Cas9 Dna Editing Applications Via In Vivo T7 Rna Polymerase Transcription In Escherichia Coli., Christian A. Santiago Jan 2023

Producing Grnas For Use In Crispr-Cas9 Dna Editing Applications Via In Vivo T7 Rna Polymerase Transcription In Escherichia Coli., Christian A. Santiago

Honors Program Theses

The development of the CRISPR-Cas9 system is widely considered to be a breakthrough advancement in gene editing. Compared to traditional technologies, CRISPR is generally regarded as the most accessible, effective, and precise tool for inducing stable and inheritable gene edits in vivo. The CRISPR-Cas9 gene editing complex relies on the complementary binding of guide RNAs to specifically target a DNA sequence for endonuclease cleavage and mutagenesis. The production of gRNAs for use in CRISPR applications can become exceedingly complex and costly, as in vivo methodologies generally require the use of RNA polymerases that interfere with gRNA sequence identity and in …


The Impact Of Microfinance On Gender Equality In India, Alexis Matton Jan 2023

The Impact Of Microfinance On Gender Equality In India, Alexis Matton

Honors Program Theses

This paper explores the impacts of microfinance on gender equality in India by examining its effects through the framework of the United Nations Sustainable Development Goals. It begins with an overview of the history of microfinance globally and is followed by an in-depth explanation of the current microfinance landscape in India. This paper then uses a case study approach to collect qualitative data that contributes to this discussion on microfinance and gender equality. By studying the stories of four women and their experiences using the services provided by microfinance institutions, the paper illustrates how microfinance contributes to the advancement of …


Reducing Multigenerational Poverty In New York Through Sentencing Reform, Jared Trujillo Jan 2023

Reducing Multigenerational Poverty In New York Through Sentencing Reform, Jared Trujillo

City University of New York Law Review

The relationship between incarceration and poverty is circular, cyclical, and symbiotic – poverty is a cause of incarceration, and incarceration causes poverty. In the 1970’s and 1990’s, New York led the country in enacting draconian sentencing laws that required judges to sentence children and adults to longer periods of incarceration, while also reducing the ability of incarcerated people to earn time off of their sentences for participation in rehabilitative, vocational, and educational programming. For the past half century, these harsh sentencing laws have been the primary driver of mass incarceration in New York. As a result, generations of families with …


Premature Senescence And Cardiovascular Disease Following Cancer Treatments: Mechanistic Insights, Ashita Jain, Diego Casanova, Alejandra Valdivia Padilla, Angelica Paniagua Bojorges, Sivareddy Kotla, Kyung Ae Ko, Venkata S K Samanthapudi, Khanh Chau, Minh T H Nguyen, Jake Wen, Selina L Hernandez Gonzalez, Shaefali P Rodgers, Elizabeth A Olmsted-Davis, Dale J Hamilton, Cielito Reyes-Gibby, Sai-Ching J Yeung, John P Cooke, Joerg Herrmann, Eduardo N Chini, Xiaolei Xu, Syed Wamique Yusuf, Momoko Yoshimoto, Philip L Lorenzi, Brain Hobbs, Sunil Krishnan, Efstratios Koutroumpakis, Nicolas L Palaskas, Guangyu Wang, Anita Deswal, Steven H Lin, Jun-Ichi Abe, Nhat-Tu Le Jan 2023

Premature Senescence And Cardiovascular Disease Following Cancer Treatments: Mechanistic Insights, Ashita Jain, Diego Casanova, Alejandra Valdivia Padilla, Angelica Paniagua Bojorges, Sivareddy Kotla, Kyung Ae Ko, Venkata S K Samanthapudi, Khanh Chau, Minh T H Nguyen, Jake Wen, Selina L Hernandez Gonzalez, Shaefali P Rodgers, Elizabeth A Olmsted-Davis, Dale J Hamilton, Cielito Reyes-Gibby, Sai-Ching J Yeung, John P Cooke, Joerg Herrmann, Eduardo N Chini, Xiaolei Xu, Syed Wamique Yusuf, Momoko Yoshimoto, Philip L Lorenzi, Brain Hobbs, Sunil Krishnan, Efstratios Koutroumpakis, Nicolas L Palaskas, Guangyu Wang, Anita Deswal, Steven H Lin, Jun-Ichi Abe, Nhat-Tu Le

The Brown Foundation: Institute of Molecular Medicine

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality, especially among the aging population. The "response-to-injury" model proposed by Dr. Russell Ross in 1999 emphasizes inflammation as a critical factor in atherosclerosis development, with atherosclerotic plaques forming due to endothelial cell (EC) injury, followed by myeloid cell adhesion and invasion into the blood vessel walls. Recent evidence indicates that cancer and its treatments can lead to long-term complications, including CVD. Cellular senescence, a hallmark of aging, is implicated in CVD pathogenesis, particularly in cancer survivors. However, the precise mechanisms linking premature senescence to CVD in cancer survivors remain …


Characterizing Cellular Injury And Inflammation With Aldob-/-Mouse Model Of Mafld, Andy Rashid Jan 2023

Characterizing Cellular Injury And Inflammation With Aldob-/-Mouse Model Of Mafld, Andy Rashid

All Master's Theses

Metabolic-associated fatty liver disease (MAFLD) affects 1 in 3 people in the US and is a healthcare burden on the order of billions of dollars. MAFLD is characterized by pathological lipid accumulation in the liver, excess production of triglycerides and cholesterol, and export of LDL particles that raise serum lipid levels. These metabolic perturbations can lead to the development of liver fibrosis, chronic inflammation, and insulin resistance. Diagnosing MAFLD prior to fibrosis is crucial for successful intervention and prevention of advanced liver disease and other metabolic complications. Fructose-1Phospahte (F1P) accumulation from fructose overconsumption can drive hepatic lipogenesis and MAFLD progression. …


Effects Of Peri-Urbanization On Coastal Sage Scrub Ant Species In Baja California, Alejandro E. Mieles, Margaret A. Voss, Estelí Jiménez-Soto Jan 2023

Effects Of Peri-Urbanization On Coastal Sage Scrub Ant Species In Baja California, Alejandro E. Mieles, Margaret A. Voss, Estelí Jiménez-Soto

School of Geosciences Faculty and Staff Publications

Increasing urbanization on the Baja California Peninsula threatens ant diversity. Reductions in ant species diminish ecosystem services provided to semiarid coastal scrub areas. Peri-urban areas in particular are at high risk of reductions in ant biodiversity due to development. To document and evaluate ant species diversity and richness in a rapidly developing area, nine sites were sampled within areas of coastal sage scrub (CSS) encircling the urban periphery of Ensenada, Baja California. Forty species and 17 genera of ants were collected, only one of which was non-native. Although the sampled area represents less than 1% of the peninsula and 3% …


Validation And Reliability Of A Questionnaire That Measures Food Waste Knowledge, Attitudes, And Motivations Of Adolescents, Joanna Fung Jan 2023

Validation And Reliability Of A Questionnaire That Measures Food Waste Knowledge, Attitudes, And Motivations Of Adolescents, Joanna Fung

Master's Theses

The goal of this thesis was to develop a valid and reliable questionnaire to measure food waste knowledge, attitudes, and motivations of adolescents aged 13 to 17 in the United States (U.S.). This questionnaire was created with the objective to address gaps in adolescent food waste literature and to aid the creation and refinement of targeted food waste programs and policies. Questions were specific to the home, school, and restaurant settings, as well as, behaviors related to discarding food, composting food, and food expiration. Additionally, the questionnaire sought to understand how friendships and familial relationships affect adolescent food waste-related behaviors. …