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Determination Of Three Sterols In Camellia Oleifera Seed Oil By Atmospheric Pressure Chemical Ionization Ultra Performance Liquid Chromatography-Time Of Flight Mass Spectrometry, Pan Jin-Hua, Chen Feng, Bai Jian-Ping, Duan Xue-Fei, Li Qi-Qi Oct 2023

Determination Of Three Sterols In Camellia Oleifera Seed Oil By Atmospheric Pressure Chemical Ionization Ultra Performance Liquid Chromatography-Time Of Flight Mass Spectrometry, Pan Jin-Hua, Chen Feng, Bai Jian-Ping, Duan Xue-Fei, Li Qi-Qi

Food and Machinery

Objective: In this study, ultra performance liquid chromatography-high resolution quadrupole time of flight mass spectrometer (UPLC-Q-TOF/MS) was established to determine β-sitosterol, brassicasterol, and campesterol in camellia oleifera seed oil. Methods: Using 6-ketocholestanol as the internal standard and performing sample extraction by heating it for 30 min and refluxing it with 50 mL ethanol. After centrifugation and layering, three sterols were separated by Xbridge BEH C18 (100 mm × 4.6 mm, 2.5 μm) Chromatographic column elution. Finally, ionized by atmospheric pressure chemical ionization source and analyzed by positive ion mode. Results: The internal standard curves of the three sterols …

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Numerical Simulation Study On Temperature Field Of Ice Slurry Pre-Cooled Broccoli, Li Gan, Wang Qing, Lu Li-Xin, Pan Liao Oct 2023

Numerical Simulation Study On Temperature Field Of Ice Slurry Pre-Cooled Broccoli, Li Gan, Wang Qing, Lu Li-Xin, Pan Liao

Food and Machinery

Objective: In order to solve the problem of complicated state in the process of pre-cooling packaging of fluid ice, it provides a basis for the application of fluid ice in the storage and transportation of fruits and vegetables, fresh-keeping and so on. Methods: Taking broccoli as the research object, the heat transfer model of pre-cooling broccoli with fluidized ice was established. The change of temperature field and ice crystal particles during the process of precooling and storage of broccoli was simulated by CFD. The effects of fluid ice crystal integral number and mass ratio of fluid ice on broccoli precooling …

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Effects On The Preservation Of Chilled Mutton By Using Polylactic Acid Nanofiber Films Loaded With Perillaldehyde, Wang De-Bao, Zou Yu-Fu, Li Jia, Yao Duo, Li Xing-Yun Oct 2023

Effects On The Preservation Of Chilled Mutton By Using Polylactic Acid Nanofiber Films Loaded With Perillaldehyde, Wang De-Bao, Zou Yu-Fu, Li Jia, Yao Duo, Li Xing-Yun

Food and Machinery

Objective: The purpose of the study was to investigate the antibacterial mechanical properties of PLA nanofiber film loaded with PAE and its preservation effect on chilled mutton. Methods: By loading different amount (0, 12.5, 25, 50, 100 μL/20 mL) of electrospinning solution perillaldehyde (PAE) in polylactic acid (PLA) matrix, the antibacterial nanofiber film packaging with certain water absorption properties was prepared through electrospinning technology. The appearance and mechanical properties of PAE-PLA packaging film and physical-chemical indexes of mutton during preservation were analyzed via scanning electron microscopy and electronic universal testing machine. Results: With the increase of loading amount of PAE …

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Effects Of Controlled Atmosphere On Storage Quality Of Water Bamboo, Ren Zi-Yan, Wei Wen-Wen, Jia Lian-Wen, Yang Xiang-Zheng, Wang Da Oct 2023

Effects Of Controlled Atmosphere On Storage Quality Of Water Bamboo, Ren Zi-Yan, Wei Wen-Wen, Jia Lian-Wen, Yang Xiang-Zheng, Wang Da

Food and Machinery

Objective: To clarify the effect of controlled atmosphere on preservation of water bamboo. Methods: Cold storage under air was used as control, the sensory quality, texture （firmness, chewiness and shear force）, color （L* value and WH value）, the contents of soluble protein, lignin and cellulose, as well as the activities of phenylalanine ammonia lyase （PAL） and polyphenoloxidase （PPO） were determined under four different gas components （CA1: 2% O2+7% CO2+91% N2, CA2: 5% O2+10% CO2+85% N2, CA3: 5% O2+7% CO2+88% N2 …

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Improvement Of Antarctic Krill Oil On Reserpine Induced Zebrafish Depression Model, Guo Meng-Jie, Liu Yun, Wu Zhi-Qiang, Jiang Guo-Liang Oct 2023

Improvement Of Antarctic Krill Oil On Reserpine Induced Zebrafish Depression Model, Guo Meng-Jie, Liu Yun, Wu Zhi-Qiang, Jiang Guo-Liang

Food and Machinery

Objective: This study aimed to investigate the effect of Antarctic krill oil on zebrafish model of depression. Methods: The zebrafish (Danio rerio) model of depression was induced by 40 mg/L reserpine, and five groups, i.e., blank control group, model group, fluoxetine group, low-dose krill oil group and high-dose krill oil group were investigated and compared, buy using new tank test (NTT) and light dark box test (LDB). The central nervous system serotonin (5-HT), dopamine (DA), monoamine oxidase A (MAO-A) Interleukin-6 (IL-6), tumor necrosis factor α (TNF-α) and systemic cortisol (COR) levels of the five groups were …

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Changes Of Quality Characteristics And Antioxidant Capacities During Fruit Development Of Hardy Kiwifruit, Zhang Liang-Ying, Liu Lin, Yu Li-Jie, Liu Qi, Qi Bian-Bin Oct 2023

Changes Of Quality Characteristics And Antioxidant Capacities During Fruit Development Of Hardy Kiwifruit, Zhang Liang-Ying, Liu Lin, Yu Li-Jie, Liu Qi, Qi Bian-Bin

Food and Machinery

Objective: This study aimed to provide theoretical basis for hardy kiwifruit quality improvement and rational utilization. Methods: Taking the main variety 'Longcheng No. 2' and line 'Haijia' as experimental materials, the changes of basic quality indexes, contents of total phenolics and flavonoids were analyzed during fruit development. On this basis, the antioxidant capacities were comprehensively evaluated by three assays (FRAP iron reducing ability, ABTS radical scavenging ability and DPPH radical scavenging ability). Furthermore, the differences of total phenolics and antioxidant capacities in different parts of fruit were compared. Results: ① The contents of soluble solids, titratable acids and Vc in …

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Antioxidant And Hypoglycemic Activities Of Different Graded Fractions Of Polysaccharide From Goldenmelon, Chen Bing-Jie, Qiao Yong-Jin, Wang Xiao, Wang Chun-Fang, Liu Gui-Ge Oct 2023

Antioxidant And Hypoglycemic Activities Of Different Graded Fractions Of Polysaccharide From Goldenmelon, Chen Bing-Jie, Qiao Yong-Jin, Wang Xiao, Wang Chun-Fang, Liu Gui-Ge

Food and Machinery

Objective: The study aimed to research the physicochemical properties, structure, antioxidant activity and hypoglycemic activity of different fractions of polysaccharide of goldenmelon. Methods: Four kinds of goldenmelon polysaccharides (CP-40, CP-60, CP-70, CP-80) were obtained by graded purification of water extraction and alcoholic precipitation. Their molecular weight, monosaccharide composition, group composition, antioxidant and hypoglycemic activities were investigated by high performance liquid chromatography and fourier transform infrared spectroscopy. Results: With the increase of ethanol volume fraction, the total sugar content increased and the glucuronic acid content decreased. The molecular weights of these four polysaccharides were different, which indicated by the same composition …

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Effects Of Different Growth Patterns On Nutritional Quality Of Nostoc Commune, Xie Jie-Fei, Wang Chao, Deng Zhong-Yang Oct 2023

Effects Of Different Growth Patterns On Nutritional Quality Of Nostoc Commune, Xie Jie-Fei, Wang Chao, Deng Zhong-Yang

Food and Machinery

Objective: Replacing wild resources with artificially cultivated Nostoc commune to protect the natural environment. Methods: Compare the biochemical composition, texture characteristics, and sensory evaluation of indoor, outdoor cultivation and wild N. commune, while using outdoor cultivation of Nostoc sphaeroides as a control in the above three aspects. Results: The ratio of dry weight to wet weight of wild N. commune was the largest （2.42%）, and its hardness and elasticity were the highest, which were 1.184 N and 78.5%, respectively. The content of phycoerythrin and polysaccharide of outdoor N. commune were the lowest, which were 0.19% and 24.45%, respectively. The …

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Study On The Effects Of Adding Konjac Refined Flour On The Quality Of Fresh Wet Rice Noodle, Gong Xue, Xie Song-Feng, Xia Zeng-Run, Wang Ai-Xia, Tong Li-Tao Oct 2023

Study On The Effects Of Adding Konjac Refined Flour On The Quality Of Fresh Wet Rice Noodle, Gong Xue, Xie Song-Feng, Xia Zeng-Run, Wang Ai-Xia, Tong Li-Tao

Food and Machinery

Objective: This study aimed to develop konjac rice noodles products with low glycemic index. Methods: The fresh wet rice noodles was made by adding 20%, 10% and 5% konjac refined flour into rice noodles, respectively. The effects of the addition of konjac refined flour on the texture, cooking performance, and sensory quality of rice noodles were studied by texture analyzer and rapid viscosity analyzer. The starch hydrolysis rate, digestion rate, and glycemic index of konjac rice noodles were studied by in vitro digestion model. Results: The cooking loss rate and turbidity of 5% konjac rice noodles were significantly reduced, and …

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Effects Of Dynamic High-Pressure Processing On Bioactive Components Of Milk, Ai Zheng-Wen, Xu Zhi-Yuan, Ye Jing-Jin Oct 2023

Effects Of Dynamic High-Pressure Processing On Bioactive Components Of Milk, Ai Zheng-Wen, Xu Zhi-Yuan, Ye Jing-Jin

Food and Machinery

Milk contains a variety of bioactive ingredients, such as lactoferrin and immunoglobulin, which are beneficial to health. Reducing the loss of these proteins during processing has always been the focus of attention. Dynamic high-pressure processing technology, also known as ultra-high-pressure homogenization (UHPH), is one of the relatively novel processing technology means. In this review, the research progress of the heat load intensity and the retention of key nutrients in the processing of dairy products were summarized from the aspects of Maillard reaction products, lactoferrin, immunoglobulin and other bioactive ingredients and vitamin loss. Moreover, the development direction of ultra-high-pressure homogenization in …

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Structure, Working Principle And Application Of Mechanical Shell Breaker, He Ting, Zhang Rui, Ren Guang-Yue, Duan Xu, Li Cai-Yun, Li Ya-Chun Oct 2023

Structure, Working Principle And Application Of Mechanical Shell Breaker, He Ting, Zhang Rui, Ren Guang-Yue, Duan Xu, Li Cai-Yun, Li Ya-Chun

Food and Machinery

Shelling rate and kernel breaking rate are the two key indicators of shelled materials, and mechanical shelling is one of the important methods to improve these key indicators. In this paper, the common mechanical shelling methods, mechanical shelling types, mechanical shelling principles and development status of shelling materials were analyzed. The advantages and disadvantages of mechanical hulling equipment were summarized, and suggestions were made for the problems existing in the current application of mechanical hulling.

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Research Progress Of Polyphenols In Edible Plant Enzymes, Yin Xiao-Qing, Wen Hua-Ying, Zhang Yu-Hong, Bai Ting, Wang Shan-Shan Oct 2023

Research Progress Of Polyphenols In Edible Plant Enzymes, Yin Xiao-Qing, Wen Hua-Ying, Zhang Yu-Hong, Bai Ting, Wang Shan-Shan

Food and Machinery

Polyphenol is one of the characteristic physical and chemical indexes of edible plant enzyme, which has the effects of anti-oxidation, reducing fat and anti-tumor. This paper reviews the composition of polyphenols in food plant enzyme products, the factors affecting the formation of polyphenols in food plant enzyme products, the health care effects of polyphenols, and the further research directions of polyphenols in edible plant enzymes are also prospected.

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Advances In Non-Thermal Treatment Techniques To Control Yogurt Post-Acidification, Niu Yu-Qin, Wang Chen-Yuan, Zhao Pei, Li Shu-Sen, Liu Ju-Long, Sun Er-Na, Wu Zi-Jian Oct 2023

Advances In Non-Thermal Treatment Techniques To Control Yogurt Post-Acidification, Niu Yu-Qin, Wang Chen-Yuan, Zhao Pei, Li Shu-Sen, Liu Ju-Long, Sun Er-Na, Wu Zi-Jian

Food and Machinery

Post-acidification is one of the most important factors affecting the sensory quality, flavor characteristics and stability of yogurt during shelf-life. Non-thermal treatments are novel methods to control post-acidification, which can maintain the original nutritional properties and sensory quality of food to the maximum extent. In this paper, the mechanism of post-acidification of lactic acid bacteria was reviewed. The mechanism and recent research progress of non-heat treatment processes such as ultra-high pressure, ultrasound, pulsed electric field, CO2 treatment, irradiation were analyzed and provided theoretical guidance for the development and industrial application of non-heat acid control technology.

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Plasma Assisted Ultrasonic-Assisted Extraction Of Chitin From Crayfish Shell By Weak Acid And Weak Base Method, Ding Zijun, Li Jinlin, Fu Yingfei, Zhang Qiuxia, Mao Yiying, Wang Wei, Peng Bin, Tu Zongcai, Zhou Yan Oct 2023

Plasma Assisted Ultrasonic-Assisted Extraction Of Chitin From Crayfish Shell By Weak Acid And Weak Base Method, Ding Zijun, Li Jinlin, Fu Yingfei, Zhang Qiuxia, Mao Yiying, Wang Wei, Peng Bin, Tu Zongcai, Zhou Yan

Food and Machinery

Objective: To explore a green and efficient method for extracting chitin. Methods: The crayfish shells were crushed through three mesh sieves to obtain the raw material. Utilizing ultrasonic wave and citric acid and urea to remove calcium and protein from the sample, decolorize it with hydrogen peroxide, filter it, and then dry it to produce chitin products. The particle size of the chitin sample was analyzed by laser scattering particle size distribution analyzer. Infrared absorption characteristics were measured by an infrared spectrometer. Scanning electron microscopy was used to observe the apparent structure of the sample. Results: It was shown that …

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Amino Acid Characteristics And Nutritional Evaluation Of Flammulina Filiformis Protoplast Hybrid Strains, Lu Huan, Liu Jianyu, Shang Xiaodong, Yang Hui, Wu Yansha, Wang Ruijuan Oct 2023

Amino Acid Characteristics And Nutritional Evaluation Of Flammulina Filiformis Protoplast Hybrid Strains, Lu Huan, Liu Jianyu, Shang Xiaodong, Yang Hui, Wu Yansha, Wang Ruijuan

Food and Machinery

Objective: This study aimed to investigate the quality differences among different hybrid enoki mushrooms （Flammulina filiformis） strains and breed new strains with high quality. Methods: Two different protoplast monocytes of yellow enoki mushrooms Fv1923 were used as one of the parents to cross with 6 enoki mushrooms protoplasts （2 yellow and 4 white strains）, and a total of 12 yellow hybrid strains were obtained. Principal component analysis and cluster analysis were used to evaluate the free amino acids of 12 hybrid strains, and the flavor diversity of different protoplast hybrid strains was also evaluated. Results: The average contents …

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Research And Application Progress Of Cold-Chain Logistics Packaging Technology Of Fresh Agricultural Products, Xiang Mingyue Oct 2023

Research And Application Progress Of Cold-Chain Logistics Packaging Technology Of Fresh Agricultural Products, Xiang Mingyue

Food and Machinery

Cold chain logistics packaging technology is crucial for the operation of perishable food chains （such as meat, fish, dairy products, fruit and vegetable products） and certain products in the pharmaceutical industry （such as vaccines, biopharmaceuticals, and blood products）. In the future, the cold chain logistics packaging of fresh agricultural products will tend towards high-performance, environmentally friendly, and digital development. The article reviews the packaging technologies used in the cold chain logistics of fresh agricultural products in recent years. Analyzes the characteristics, use value, application scope, technical advantages and disadvantages of different packaging materials, and analyzes the potential cold chain logistics …

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Apple Surface Defect Detection Based On Improved Cnn And Data Augmentation, Pi Wei, Qu Xilong, Wang Shaocheng, Li Qingchun Oct 2023

Apple Surface Defect Detection Based On Improved Cnn And Data Augmentation, Pi Wei, Qu Xilong, Wang Shaocheng, Li Qingchun

Food and Machinery

Objective: Improve the detection accuracy and efficiency of apple surface defects. Methods: An detection method for apple surface defects was established based on an improved convolutional neural network (CNN) and data augmentation method. Firstly, the classical CNN was improved to detect apple surface defects. Then, using the conditional generation adversarial network, the image data of surface defect free and defective apples was augmented with synthetic apple images to improve the detection performance of the improved CNN for apple surface defects. Finally, by pruning the CNN model, the detection accuracy, detection speed and energy saving limits of apple surface defects were …

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Ud In The News Oct. 14-20, 2023, University Of Dayton Oct 2023

Ud In The News Oct. 14-20, 2023, University Of Dayton

News Releases

Stations nationwide aired Erica Neuman's Marketplace interview about the IRS trying to make filing taxes easier. The Conversation, Newsweek, Catholic World Report, FoodService Director and Construction Dive highlighted UD expertise and initiatives.

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Domoic Acid In Canadian Pacific Waters, From 2016 To 2021, And Relationships With Physical And Chemical Conditions, R. Ian Perry, Nina Nemcek, Melissa Hennekes, Akash Sastri, Andrew R.S. Ross, Hayleigh Shannon, Ryan B. Shartau Oct 2023

Domoic Acid In Canadian Pacific Waters, From 2016 To 2021, And Relationships With Physical And Chemical Conditions, R. Ian Perry, Nina Nemcek, Melissa Hennekes, Akash Sastri, Andrew R.S. Ross, Hayleigh Shannon, Ryan B. Shartau

Biology Faculty Publications and Presentations

Domoic acid, a phycotoxin produced by species of the marine diatom Pseudo-nitzschia, can cause deleterious impacts to marine food webs and human health. Domoic acid and Pseudo-nitzschia spp. were surveyed from 2016 to 2021 in the Pacific waters of Canada to assess their occurrences, concentrations, and relationships with physical and chemical conditions. Domoic acid was common, occurring in measurable concentrations in 73% of the 454 samples. It occurred in all regions (west coast of Vancouver Island, Salish Sea, Queen Charlotte Sound /Hecate Strait, deep oceanic NE Pacific), in all years and all seasons. Median concentrations were highest along the west …

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Secondary Traumatic Stress And Other Contributors To Teacher Burnout And Attrition, Mary Snellings W. Inabnett Oct 2023

Secondary Traumatic Stress And Other Contributors To Teacher Burnout And Attrition, Mary Snellings W. Inabnett

LSU Master's Theses

Teachers are the most important factor in eliciting positive student outcomes. Yet, teacher attrition is an increasing problem, due to the demands of the profession. These demands are exacerbated in high-needs schools, which serve students who are exposed to higher levels of stress and trauma. It is understood that, because of the populations high-needs schools serve, teachers who work in these schools are exposed to secondary traumatic stress (STS) at higher rates than other teachers. What is less clear is if STS exposure contributes to teacher attrition, beyond other known factors. The current study surveyed 104 teachers from a school …

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Does Chicken Soup Really Help When You’Re Sick? A Nutrition Specialist Explains What’S Behind The Beloved Comfort Food, Colby Teeman Oct 2023

Does Chicken Soup Really Help When You’Re Sick? A Nutrition Specialist Explains What’S Behind The Beloved Comfort Food, Colby Teeman

Materials from the University of Dayton Magazine Website

Does chicken soup really help when you’re sick? A nutrition specialist explains what’s behind the beloved comfort food

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Nutritional Challenges Of Substituting Farmed Animals For Wild Fish In Human Diets, Sebastian A. Heilpern, Rafael M. Almeida, Kathryn J. Fiorella, Alexander S. Flecker, Demetra Williams, Peter B. Mcintyre Oct 2023

Nutritional Challenges Of Substituting Farmed Animals For Wild Fish In Human Diets, Sebastian A. Heilpern, Rafael M. Almeida, Kathryn J. Fiorella, Alexander S. Flecker, Demetra Williams, Peter B. Mcintyre

School of Earth, Environmental, & Marine Sciences Faculty Publications

Wild fisheries provide billions of people with a key source of multiple essential nutrients. As fisheries plateau or decline, nourishing more people will partially rely on shifting consumption to farmed animals. The environmental implications of transitions among animal-sourced foods have been scrutinized, but their nutritional substitutability remains unclear. We compared concentrations of six essential dietary nutrients across >5000 species of wild fishes, aquaculture, poultry and livestock species, representing >65% of animals consumed globally. Wild fishes are both more nutrient-dense and variable than farmed animals; achieving recommended intake of all nutrients with farmed species could require consuming almost four times more …

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Effects Of Hydroxyl Safflower Yellow A On Lipopolysaccharide Induced Depression Model Rats, Yiming Gaghafu, Mian Qiang-Hui, Han Nan-Yin, Abudureyimu Yusufu Oct 2023

Effects Of Hydroxyl Safflower Yellow A On Lipopolysaccharide Induced Depression Model Rats, Yiming Gaghafu, Mian Qiang-Hui, Han Nan-Yin, Abudureyimu Yusufu

Food and Machinery

Objective: This study aimed to investigate the antidepressant effect of hydroxyl safflower yellow A on rats induced by lipopolysaccharide. Methods: The depression model of rats was established by intraperitoneal injection of LPS. The normal control group, the model group, the positive control group and the hydroxyl safflower yellow A groups with different doses were set up, and the depression like behavior of rats was evaluated. The contents of TNF-α, IL-1β, IL-6 and BDNF, 5-HT in serum of rats were determined, and the histopathological changes of hippocampus were observed. The protein expression of TLR/NLR signaling pathway was detected. Results: …

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Effects Of Ethanol And Methyl Jasmonate Fumigation On The Quality Of Bamboo Shoots During Storage, Xu Jing-Yang, Ji Ning, Wang Rui, Zhang Ni, Liu Ren-Chan, Wang Si-Yuan, Deng Yun-Bing Oct 2023

Effects Of Ethanol And Methyl Jasmonate Fumigation On The Quality Of Bamboo Shoots During Storage, Xu Jing-Yang, Ji Ning, Wang Rui, Zhang Ni, Liu Ren-Chan, Wang Si-Yuan, Deng Yun-Bing

Food and Machinery

Objective： This study aimed to provide a basis for the post-harvest storage and preservation of fresh shoots from bamboo (Chimonobambusa quadrangularis). Methods: Fresh bamboo shoots were fumigated with 500 μL/L anhydrous ethanol and 0.1 mmol/L MeJA, and distilled water was used as blank control (CK) to determine the storage period, i. e. temperature (1.0±0.3) ℃ and relative humidity (90±5)%. The respiratory intensity, hardness, browning index, soluble protein, and activity of PAL, POD, PPO and APX were detected. The quality differences of fresh bamboo shoots during storage were analyzed using principal component analysis. Results: Combined fumigation treatment can reduce …

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Fermentation Process Optimization And Flavor Composition Analysis Of Plum Peppermint Wine, Guo Ming-Yi, Deng Yan, Du Qian-Hong, Wu Hua-Chang Oct 2023

Fermentation Process Optimization And Flavor Composition Analysis Of Plum Peppermint Wine, Guo Ming-Yi, Deng Yan, Du Qian-Hong, Wu Hua-Chang

Food and Machinery

Objective: In order to develop and enrich fruit wine categories and diversify sensory levels, plum and peppermint were chosen out as the main materials for fermenting a compound fruit wine. Methods: Single factor test and response surface test were used to analyze the effects of mint addition amount, initial sugar degree, initial pH value and fermentation temperature on the alcohol and quality of plum peppermint wine. The fermentation process was optimized, and its sensory was analyzed. Moreover, the sensory, physical and chemical indexes and volatile components were detected. Results: The optimum fermentation conditions were as follows: peppermint content 18%, initial …

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Optimization Of Complex Enzymatic Extraction Process Of Steroidal Glycosides From Cynanchum Auriculatum Royle Ex Wight And Its Hepatoprotective Activity, Song Wan-Yu, Dai Jing, Feng Jin, Li Chun-Yang, Ma Yong-Qiang Oct 2023

Optimization Of Complex Enzymatic Extraction Process Of Steroidal Glycosides From Cynanchum Auriculatum Royle Ex Wight And Its Hepatoprotective Activity, Song Wan-Yu, Dai Jing, Feng Jin, Li Chun-Yang, Ma Yong-Qiang

Food and Machinery

Objective: Response surface methodology was used to optimize the extraction process of steroidal glycosides from Cynanchum auriculatum Royle ex Wight by complex enzymatic method, and its effects on alcohol dehydrogenase activity and human hepatoma cell HepG2 were analyzed. Methods: Four experimental factors; enzymolysis duration, temperature, compound enzyme dose and pH were used as responses to a single-factor experiment of the Response Surface Methodology on the steroidal glycoside yields, using perennial C. auriculatum as the target material. The alcohol-induced hepatocyte damage model of HepG2 was used to investigate the contents of ALT, LDH, and GSH and changes in cell shape. Results: …

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Research Progress In Nutritional Composition And Biological Function Of Grape Seed Extracts, Zhou Xiang-Hui Oct 2023

Research Progress In Nutritional Composition And Biological Function Of Grape Seed Extracts, Zhou Xiang-Hui

Food and Machinery

Grape seed extracts, due to its strong antioxidant activity, is commonly used as a nutritional supplement or dietary supplement. It can be used to prevent metabolic diseases such as inflammation, tumors, and atherosclerosis. This article provides an overview of the nutritional composition and biological functions of grape seed extracts, summarizes the latest research findings on the bioactive ingredients in grape seed extracts in terms of antioxidant, anti-inflammatory, anti-tumor, antimicrobial, and anti-atherosclerosis effects, and discusses the shortcomings and future research directions in grape seed extracts research.

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Cystic Fibrosis Year In Review 2022, Jeeyeon Kim, Benjamin Lyman, Adrienne P. Savant Oct 2023

Cystic Fibrosis Year In Review 2022, Jeeyeon Kim, Benjamin Lyman, Adrienne P. Savant

School of Medicine Faculty Publications

Remarkable medical advancements have been made for people with cystic fibrosis (CF) in recent years, with an abundance of research continuing to be conducted worldwide. With concern for limitations in access to highly effective CFTR modulators, as well as the recent Coronavirus Disease-19 pandemic, there has been a consistent effort to understand and improve CF screening, disease burden, diagnosis, and management. Our aim in this review is to present articles from 2022 with an emphasis on clinically relevant studies. We hope this will serve as a broad overview of the research published in the past year.

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Early Resveratrol Treatment Mitigates Joint Degeneration And Dampens Pain In A Mouse Model Of Pseudoachondroplasia (Psach), Jacqueline T Hecht, Alka C Veerisetty, Debabrata Patra, Mohammad G Hossain, Frankie Chiu, Claire Mobed, Francis H Gannon, Karen L Posey Oct 2023

Early Resveratrol Treatment Mitigates Joint Degeneration And Dampens Pain In A Mouse Model Of Pseudoachondroplasia (Psach), Jacqueline T Hecht, Alka C Veerisetty, Debabrata Patra, Mohammad G Hossain, Frankie Chiu, Claire Mobed, Francis H Gannon, Karen L Posey

Faculty, Staff and Student Publications

Pseudoachondroplasia (PSACH), a severe dwarfing condition associated with early-onset joint degeneration and lifelong joint pain, is caused by mutations in cartilage oligomeric matrix protein (COMP). The mechanisms underlying the mutant-COMP pathology have been defined using the MT-COMP mouse model of PSACH that has the common D469del mutation. Mutant-COMP protein does not fold properly, and it is retained in the rough endoplasmic reticulum (rER) of chondrocytes rather than being exported to the extracellular matrix (ECM), driving ER stress that stimulates oxidative stress and inflammation, driving a self-perpetuating cycle. CHOP (ER stress signaling protein) and TNFα inflammation drive high levels of mTORC1 …

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Early Resveratrol Treatment Mitigates Joint Degeneration And Dampens Pain In A Mouse Model Of Pseudoachondroplasia (Psach), Jacqueline T Hecht, Alka C Veerisetty, Debabrata Patra, Mohammad G Hossain, Frankie Chiu, Claire Mobed, Francis H Gannon, Karen L Posey Oct 2023

Early Resveratrol Treatment Mitigates Joint Degeneration And Dampens Pain In A Mouse Model Of Pseudoachondroplasia (Psach), Jacqueline T Hecht, Alka C Veerisetty, Debabrata Patra, Mohammad G Hossain, Frankie Chiu, Claire Mobed, Francis H Gannon, Karen L Posey

Faculty, Staff and Student Publications

Pseudoachondroplasia (PSACH), a severe dwarfing condition associated with early-onset joint degeneration and lifelong joint pain, is caused by mutations in cartilage oligomeric matrix protein (COMP). The mechanisms underlying the mutant-COMP pathology have been defined using the MT-COMP mouse model of PSACH that has the common D469del mutation. Mutant-COMP protein does not fold properly, and it is retained in the rough endoplasmic reticulum (rER) of chondrocytes rather than being exported to the extracellular matrix (ECM), driving ER stress that stimulates oxidative stress and inflammation, driving a self-perpetuating cycle. CHOP (ER stress signaling protein) and TNFα inflammation drive high levels of mTORC1 …

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