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Crop Water Use And A Gravity Model Exploration Of Virtual Water Trade In Ghana's Cereal Agriculture, Alexander Sessi Kosi Tette, Golden Odey, Mirza Junaid Ahmad, Bashir Adelodun, Kyung-Sook Choi

Arusha Climate and Environmental Research Centre

Agricultural water productivity is crucial for sustainability amidst the escalating demand for food. Cereals are pivotal in providing nutritious food at affordable prices. This study was based on Ghanaian data spanning from 1992 to 2021 to evaluate water usage in the cultivation of major cereals. It also examined the virtual water losses or gains in cereal trade alongside influencing factors. The analysis utilized secondary data encompassing the virtual water content, production quantity, export and import quantities, distance, GDP per capita, population, and land per capita of Ghana and its 75 trade partners. In the last 5 years, crop water use …

A Growing Dome In The Clouds Of Everest: An Applied Anthropology Project In The High Himalaya, Gary Mark Lesley

All Graduate Theses, Dissertations, and Other Capstone Projects

Presented is a novel approach to addressing food insecurity within a remote indigenous community situated in the high Himalaya of Nepal. The village faces challenges in accessing fresh, affordable produce, particularly during harsh winter seasons. This threatens the community's food sovereignty and adversely affects the stability of the Sir Edmund Hillary School, a site of historical and cultural importance. Through the integration of indigenous knowledge and technological advancements, this APP details a strategy to augment local agriculture, drawing on applied anthropological methodologies. The genesis of this project stems from the creative leadership of the school principal and his vision for …

Genetic Diversity Of Paxistima Canbyi A. Gray: Conserving A Rare Plant Species Endemic To The Eastern United States, Isaac Buabeng

Master’s Theses

Premise: The glacial cycles of the Pleistocene period likely had a profound impact on the genetic diversity and phylogeographic patterns of numerous plant taxa in North America. However, the genetic diversity of rare, limestone-endemic woody species has not been highlighted. This study assesses genetic diversity in Paxistima canbyi A. Gray (Canby’s mountain lover or rat stripper), a rare limestone endemic small woody plant.

Methods: We investigated the genetic diversity of P. canbyi using genomic Single Nucleotide Polymorphism (SNP) data from 165 individuals from 14 populations sampled from across the entire range distribution. We first; de novo assembled the SNP …

Creation Of A Survey And Study On Sleep Habits Of College Students, Sierra Stein

Williams Honors College, Honors Research Projects

Sleep is extremely important in all aspects of life. From the time someone is born to the time they pass they need sleep. It is crucial for their abilities to function and live their day to day lives. However, in different parts of life sleep is more crucial than ever. Young adults/college age students are one of those groups who need sleep but tend to pass up on adequate sleep. Throughout this, there will be the detailed importance of sleep and one way in which sleep can be studied in correlation to academics, physical health, eating habits, mental health and …

Research News, Publications, 2024, Volume 2, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of April 1 through June 30, 2024.

Research News, Publications, 2024, Volume 3, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of July 1 through September 30, 2024.

Research News, Publications, 2024, Volume 4, Joshua Sharp

Publications (2015-)

Publications that appeared during the period of October 1 - December 31, 2024.

Biomolecule Screen Identifies Several Inhibitors Of Salmonella Enterica Surface Colonization, Joseph Headrick, Amital Ohayon, Shannon Elliott, Jacob Schultz, Erez Mills, Erik Petersen

Faculty Open Access Works

Salmonella enterica is a foodborne pathogen commonly found in agricultural facilities; its prevalence, as well as increasing levels of disinfectant- and antibiotic-resistance, has significant costs for agriculture as well as human health. In an effort to identify potential new inhibitors of S. enterica on abiotic surfaces, we developed a biomolecule screen of nutrient-type compounds because nutrients would have lower toxicity in animal facilities and bacterial nutrient utilization pathways might prove less susceptible to the development of bacterial resistance. After screening 285 nutrient-type compounds, we identified ten that significantly inhibited the ability of S. enterica to colonize a plastic surface. After …

Gait Kinematics In Sled Dog Fitness, Ashley Maio

Williams Honors College, Honors Research Projects

The sport of sled dog racing has become popular in recent years, where teams of dogs navigate Arctic conditions anywhere from a few hundred to a thousand miles, usually within 10 days. To prepare for these competitions, dogs are subjected to rigorous training months prior to the race that results in significant changes to the physiology of their bones and muscles. This study aims to determine differences in gait kinetics between female and male sled dogs. Ten dogs, five females and five males, were recorded trotting from a lateral view for three weightbased trials to simulate different amounts of weight …

Simply Butter (One Pat At A Time), Maddie Mcsweeney

Williams Honors College, Honors Research Projects

Simply Butter (one pat at a time) is an investigation of food and intimacy through sculpture, installation, performance, printmaking, and recordkeeping. In this series of Happenings, I explore themes of love, loss, and empathy while dealing with emotions related to grief and mental health issues. I look to cultural phenomena and art history figures who are concerned with similar sentiments to make conceptual connections and inform my choices when creating this project. Drawn to silliness and the absurd, I use the rudimentary yet familiar form of a stick of butter to act as a monolithic stand-in for the emotionally, mentally, …

Impacts To Anxiety, Depression, And Psycho-Spiritual Metrics After Ketamine-Assisted Psychotherapy In Palliative Care Patients At The Aims Institute, Thomas Luedeke

Doctor of Nursing Practice Projects

There is considerable evidence that palliative care patients disproportionately experience anxiety, depression, and existential distress related to their chronic illnesses. Additionally, conventional therapies tend to be less effective in the treatment of this patient population. As such, research is being conducted into novel therapies. One of the promising therapies currently under active investigation is ketamine-assisted psychotherapy (KAP) which involves a combination of the administration of the dissociative anesthetic ketamine combined with psychotherapy.

Two clinical trials are being conducted at the Advanced Integrative Medical Sciences (AIMS) Institute in Seattle, WA, the purposes of which are to evaluate integrative care for patients …

Increasing Rates Of Secondary Referral Services In The Outpatient Setting For Patients With Uncontrolled Diabetes Mellitus, Steven Barrett

Doctor of Nursing Practice Projects

Diabetes incidence has increased in the United States since 1994 and remains amongst the top ten chronic diseases in the United States. Roughly thirty-four million Americans have diabetes and nearly $97 billion is spent annually on hospital admissions as a direct result of preventable diabetic health complications. Diabetes is often coined as a “silent illness” since 46.5% of affected individuals are unaware of their diagnosis. Primary care providers are at the forefront of diabetes management. In addition to oral medications and insulin administration, lifestyle changes and diabetic education remain the cornerstone of effective diabetes management. Evidence shows secondary referral services …

Implementation And Evaluation Of An In-Service Training On Gestational Diabetes For Non-Cdces Staff Nurses, Sogol Sedghi

Doctor of Nursing Practice Projects

Background: Gestational Diabetes Mellitus (GDM) is a prevalent pregnancy complication with significant maternal and fetal risks. Despite the critical role of nurses in managing GDM, many lack specialized training in this area. This quality improvement project aimed to enhance the knowledge, confidence, and skills of non-CDCES staff nurses in managing GDM through an in-service training program.

Method: Pre-intervention and post-intervention surveys measured the effectiveness of an educational intervention comprising of an overview of GDM, subcutaneous insulin administration, glucometer use, and postpartum management in improving nurses' self-reported confidence and knowledge. Nine non-CDCES staff nurses participated in the mandatory training, and data …

Evaluating The Efficacy Of The Diabetic Self-Management Education And Support (Dsmes) Program Among Asian Americans With Type 2 Diabetes, Joanne Saivong

Doctor of Nursing Practice Projects

Background and purpose: Despite affecting individuals of varying ages, Type 2 Diabetes Mellitus is a chronic disease that most often develops in individuals aged 45 years or older. Socioeconomic, demographic, environmental, and genetic factors contribute to risk factors for Type 2 Diabetes mellitus. If left uncontrolled, it can lead to various other health complications. Treatment of diabetes involves self-management, which includes a healthy diet, adequate physical activity, medication adherence, and healthy coping. Diabetes Self-Management and Education programs have been crucial in assessing patients’ understanding of their disease and helping to educate them on the importance of treatment. Diabetes Self-Management and …

“The Times They Are A Changin’”: Generational Comparisons Of The Civil Rights Movement With The Current-Day Climate Movement, Robin Boyle-Laisure

Faculty Publications

(Excerpt)

Bob Dylan’s famous song lyric, capturing the spirit of the 1960s, is just as apropos today: “The times they are a changin’” (1964). The civil rights movement changed history by securing legislation and court decisions advancing the constitutional rights of black people (Dalton 2008, 7). The movement took flight at a time when the Baby Boomer generation was politically active and seeking social change. As outlined in the introduction to this book, the generations and their birth years are as follows: Silents (1925–45); Baby Boomers (1946–64); Gen X (1965–80); Millennials (1981–95); and Gen Z (1996–2013). Baby Boomers “experienced the …

Understanding The Role Of Early-Stage Seed Development On Final Seed Weight By Linking Seed Physiology, Transcriptomics, And Environments In Soybean (Glycine Max (L.) Merr.), Ashwini Shivakumar

Theses and Dissertations--Plant and Soil Sciences

Soybeans, which are widely grown in the United States, are used as food, animal feed, and industrial oil. The rise in plant-based diets highlights the high protein content and versatility of soybean. Understanding seed development is crucial for increasing yield. Soybean seed development includes three phases: lag, seed-filling, and maturation. Post-fertilization, the seed undergoes cell division in the lag phase, forming the embryo, endosperm, and seed coat. The embryo absorbs the endosperm and develops into two cotyledons. During the seed-filling phase, cotyledon cells accumulate starch, proteins, and lipids. During maturation, seeds dry out and become quiescent. Studies indicate that the …

Development Of An Executive Functioning Intervention To Improve Asthma Self-Management In Black Adolescents And Young Adults: Preliminary Feedback And Future Considerations, Kelsey L. Jong

Master's Theses and Doctoral Dissertations

n the United States, asthma is the most common chronic medical condition in youth, and it disproportionately affects Black adolescents. Numerous studies document poor asthma self-management for adolescents and young adults (AYAs), which compromises treatment effectiveness and drives up healthcare costs. However, it remains unclear how to increase health-promoting behaviors and reduce health disparities between Black AYAs and other races who experience better asthma-related outcomes. Interventions have been developed to improve adolescent self-management, yet few comprehensively address the psychological, cognitive, and contextual components that may interfere with an AYA's engagement in health behaviors, and few have developed interventions utilizing AYA …

Atg11 And Atg9 Interaction In Selective Autophagy, Chimi Dolker Sherpa

Master's Theses and Doctoral Dissertations

Selective autophagy, induced by cellular stresses, degrades/recycles a specific cargo. Ithelps prevent diseases like Parkinson’s, Huntington's, cancer, and bacterial infections. It involves the formation of an autophagosome, a double-membrane vesicle that takes the cargo to the vacuole/lysosome for degradation. Atg11, the central organizer of selective autophagy, acts as a scaffold protein, interacting with Atg9, Atg1 and other Atg proteins. Our research focuses on finding mutations in Atg11 that specifically disrupt its interaction with Atg9 without affecting its dimerization or interaction with Atg1. We targeted residues 455-535 of Atg11 as a putative Atg9 interaction site, performing mutagenesis on four key residues …

Relationship Between Socking Rate And Production Of Stocker Hybrid Tilapia And Water Quality In A Mixtotrophic Biofloc System, Bartholomew W. Green, Steven D. Rawles, Candis L. Ray, Matthew E. Mcentire

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Intensified production of stocker-size tilapia can be accomplished using the biofloc technology production system. Stocker-size tilapia (ca. 10–200 g/fish) are raised for subsequent stocking for grow-out to market size. The relationship between stocking rate and the production of stocker-size hybrid tilapia (Oreochromis aureus x O. niloticus) was evaluated in two studies in outdoor mixotrophic biofloc tanks. Hybrid tilapia were stocked in 18.6-m² (15.7-m³) tanks at 50–150 fish/m² (59–178 fish/m³) in 25 fish/m² (30 fish/m³) increments in Study 1 and grown for 141–143 days. Stocking rates evaluated in 4.7-m …

A Comparison Of Concurrent Training And Moderate Intensity Continuous Training In Patients With Coronary Artery Disease, Amanda Alfaro-Chaverri, John Quindry, Charles Dumke, Brian Loyd

Graduate Student Theses, Dissertations, & Professional Papers

Moderate intensity continuous training (MICT) is the most studied method in cardiac rehabilitation (CR) for patients with coronary artery disease (CAD). Traditionally, resistance training has been utilized as a secondary role in CR. Recent interest in the topic suggests that MICT and resistance training should be applied collectively, an approach termed concurrent training (CT). The collective understanding of the potential of CT in CR patients is currently lacking.

Purpose: The aim of this professional paper is to analyze scientific evidence regarding the efficacy and safety of CT versus MICT. The analysis will focus on five primary measurements: exercise capacity, cardiovascular …

Prevalence Of Resistant Escherichia Coli Isolated From Local Meats Sold In Tema Metropolis, Ghana, Frederick Adzitey, Innocent Allan Anachinaba, Charles Addo-Quaye Brown, Nurul Huda, Masmuniri Rambli

ASEAN Journal on Science and Technology for Development

Contamination of meat by Escherichia coli (E. coli) can take its source from the live animal or by cross contamination. The study determined the prevalence of resistance of E. coli isolated from locally produced meats in the Tema Metropolis. Beef (n=200), chicken (n=200) and pork (n=200) were randomly selected and evaluated for the presence of E. coli using the procedure in the Bacteriological Analytical Manual of USA-FDA. The disc diffusion method was used for antibiotic susceptibility test of E. coli (n=55) isolates. Locally produced beef (67%), chicken (41%) and pork (23%) were contaminated by E. coli. Escherichia coli isolates were …

A Phytochemical Analysis Of Secondary Metabolites In Eupatorium Serotinum, Elise Snow

Theses and Dissertations

Phytochemistry, a subset of Natural Products Chemistry, studies chemically derived products from natural substances. Advances in this field have important applications in medicinal research due to the distinctive and unique properties of natural compounds. All metabolites are produced from the metabolic cycle, which is a pathway that provides energy for the organism. These metabolic compounds vary greatly and are classified based on their function within the organism. Primary metabolites are abundant and contribute to organism growth, development, and maintenance of energy. Secondary metabolites are found in lesser quantity and correlate to natural defense mechanisms. For example, salicylic acid is a …

Personalized Medical Predictions, Bhargavi Chevva

Master's Projects

Over the past few years, personalized medicine has gained traction due to its ability to solve medical issues efficiently for a person based on their personal characteristics. This project aims to design a machine-learning model that can generate predictions of lab test scores in the future based on past medical history. The model is trained using the MIMIC-4 (Medical Information Mart for Intensive Care) dataset that consists of medical records of over 40,000 patients. The proposed model, MOE-BEHRT, consists of Bidirectional Encoder Representations from Transformers on Electronic Health Records (BEHRT) and Mixture of Experts (MOE). The BEHRT model was originally …

Feasible Diet And Circadian Interventions Reduce In Vivo Progression Of Flt3-Itd-Positive Acute Myeloid Leukemia, Megan Rodriguez, Baharan Fekry, Brianna Murphy, Mary Figueroa, Tiewei Cheng, Margaret Raber, Lisa Wartenberg, Donna Bell, Lisa Triche, Karla Crawford, Huaxian Ma, Kendra Allton, Ruwaida Ahmed, Jaime Tran, Christine Ranieri, Marina Konopleva, Michelle Barton, Cesar Nunez, Kristin Eckel-Mahan, Joya Chandra

Faculty, Staff and Student Publications

BACKGROUND: Acute myeloid leukemia (AML) with an internal tandem duplication in the fms-like tyrosine kinase receptor 3 gene (FLT3-ITD) is associated with poor survival, and few studies have examined the impact of modifiable behaviors, such as nutrient quality and timing, in this subset of acute leukemia.

METHODS: The influence of diet composition (low-sucrose and/or low-fat diets) and timing of diet were tested in tandem with anthracycline treatment in orthotopic xenograft mouse models. A pilot clinical study to test receptivity of pediatric leukemia patients to macronutrient matched foods was conducted. A role for the circadian protein, BMAL1 (brain and muscle ARNT-like …

Sequencing Conversational Turns In Peer Interactions: An Integrated Approach For Evidence-Based Conversational Agent For Just-In-Time Nicotine Cravings Intervention, Tavleen Singh, Michael Truong, Kirk Roberts, Sahiti Myneni

Faculty, Staff and Student Publications

BACKGROUND: Risky health behaviors place an enormous toll on public health systems. While relapse prevention support is integrated with most behavior modification programs, the results are suboptimal. Recent advances in artificial intelligence (AI) applications provide us with unique opportunities to develop just-in-time adaptive behavior change solutions.

METHODS: In this study, we present an innovative framework, grounded in behavioral theory, and enhanced with social media sequencing and communications scenario builder to architect a conversational agent (CA) specialized in the prevention of relapses in the context of tobacco cessation. We modeled peer interaction data (n = 1000) using the taxonomy of behavior …

New-Onset Diabetes Is A Predictive Risk Factor For Pancreatic Lesions In High-Risk Individuals: An Observational Cohort Study, Seyda Baydogan, Chirayu Mohindroo, Merve Hasanov, Maria F Montiel, Pompeyo Quesada, Irina M Cazacu, Adrianna A Luzuriaga Chavez, Maureen E Mork, Wenli Dong, Lei Feng, Y Nancy You, Banu Arun, Eduardo Vilar, Powel Brown, Matthew H G Katz, Suresh T Chari, Anirban Maitra, Eric P Tamm, Michael P Kim, Manoop S Bhutani, Florencia Mcallister

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVES: Pancreatic cancer (PC) is the third cause of cancer-related deaths. Early detection and interception of premalignant pancreatic lesions represent a promising strategy to improve outcomes. We evaluated risk factors of focal pancreatic lesions (FPLs) in asymptomatic individuals at hereditary high risk for PC.

METHODS: This is an observational single-institution cohort study conducted over a period of 5 years. Surveillance was performed through imaging studies (EUS or magnetic resonance imaging/magnetic resonance cholangiopancreatography) and serum biomarkers. We collected demographic characteristics and used univariate and multivariate logistic regression models to evaluate associations between potential risk factors and odd ratios (ORs) …

Linking Artificial Sweetener Intake With Kidney Function: Insights From Nhanes 2003-2006 And Findings From Mendelian Randomization Research, Zhuoling Ran, Yuxuan Zheng, Lin Yu, Yuxian Zhang, Zhenjiang Zhang, Huijie Li, Xuhan Li, Jing Song, Li Zhang, Ran Zhang, Chang Lu, Yang Gong, Jian Gong

Faculty, Staff and Student Publications

BACKGROUND: The current investigation examines the association between artificial sweetener (AS) consumption and the likelihood of developing chronic kidney disease (CKD), along with its impact on kidney function.

METHODS: We utilized data from the National Health and Nutrition Examination Survey from 2003-2006 to conduct covariance analysis and weighted adjusted logistic regression, aiming to assess the association between artificial sweetener intake and CKD risk, as well as kidney function indicators. Subsequently, we employed Mendelian randomization methods to validate the causal relationship between the intake of artificial sweeteners, CKD risk, and kidney function indicators. Instrumental variable analysis using inverse-variance weighting and Robust …

Secondhand Tobacco Smoke Exposure In Homes And Vehicles In Youth: Disparities Among Racial, And Sexual And Gender Minorities, Rajesh Talluri, Sahil S Shete, Surendra S Shastri, Sanjay Shete

Faculty, Staff and Student Publications

BACKGROUND: Secondhand smoke exposure (SHSe) among youth is a serious public health concern, leading to an increased risk of conditions such as asthma and respiratory infections. However, there is little research on SHSe among vulnerable populations, such as racial and sexual minorities. Understanding the factors associated with youth SHSe in homes and vehicles is crucial to developing better protective policies.

METHODS: This study utilized 2020 data from the National Youth Tobacco Survey, a representative sample of middle- and high-school students in the US. The primary outcomes were youth SHSe at home and while riding in a vehicle. Multinomial regression models …

Higher Il-6 And Il-4 Plasma Levels In Depressed Elderly Women Are Influenced By Diabetes Mellitus, Natália S Dias, Antônio L Teixeira, Breno S Diniz, Erica L Vieira, Bernardo De M Viana, Izabela G Barbosa

Faculty, Staff and Student Publications

OBJECTIVE: This study aimed at investigating a set of peripheral cytokines in elderly female patients with MDD, comparing them to controls, and assessing the potential influence of clinical comorbidities on inflammatory markers.

METHODS: Twenty-five elderly female patients diagnosed with MDD and 19 age-matched female controls were enrolled on this study. Plasma levels of interleukin (IL)-4, IL-6, IL-10, interferon (IFN)-γ and tumor necrosis factor (TNF)-α were evaluated with commercially-available assays.

RESULTS: Elderly female patients with MDD exhibited higher plasma IL-6 and IL-4 levels when compared to controls. In a logistic regression model taking cytokine levels, comorbidities, and age into account, only …

Toxicity In The Era Of Immune Checkpoint Inhibitor Therapy, Synat Keam, Naimah Turner, Fernanda G Kugeratski, Rene Rico, Jocelynn Colunga-Minutti, Rayansh Poojary, Sayan Alekseev, Anisha B Patel, Yuanteng Jeff Li, Ajay Sheshadri, Monica E Loghin, Karin Woodman, Ashley E Aaroe, Sarah Hamidi, Priyanka Chandrasekhar Iyer, Nicolas L Palaskas, Yinghong Wang, Roza Nurieva

Faculty, Staff and Student Publications

Immune checkpoint inhibitors (ICIs) reinvigorate anti-tumor immune responses by disrupting co-inhibitory immune checkpoint molecules such as programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4). Although ICIs have had unprecedented success and have become the standard of care for many cancers, they are often accompanied by off-target inflammation that can occur in any organ system. These immune related adverse events (irAEs) often require steroid use and/or cessation of ICI therapy, which can both lead to cancer progression. Although irAEs are common, the detailed molecular and immune mechanisms underlying their development are still elusive. To further our understanding …