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Articles 21211 - 21240 of 240435
Full-Text Articles in Entire DC Network
Corn Leaf Disease Prediction Using Deep Learning, Meghana Varayuri
Corn Leaf Disease Prediction Using Deep Learning, Meghana Varayuri
Electronic Theses, Projects, and Dissertations
Corn is a widely cultivated agricultural product, serving as a cornerstone in food production and industrial applications such as biofuels, playing a crucial role in the global economy. This study explores the application of deep transfer learning to accurately classify major corn diseases from leaf images, aiming to enhance disease management strategies for improved agricultural productivity and sustainability. The customized Dense net 201 model achieved 95% prediction accuracy on an untrained dataset. Data augmentation improved the model’s accuracy from 91% to 95%. This supervised learning approach enhances the model’s performance by increasing the diversity, leading to better generalization and accuracy. …
Emotional Eating In Adolescents With Obesity: Case Series, Paula Dayan
Emotional Eating In Adolescents With Obesity: Case Series, Paula Dayan
Electronic Theses, Projects, and Dissertations
Childhood obesity remains a significant public health concern, with substantial implications for physical and mental well-being. This thesis aims to explore the intricate relationship between emotional eating and obesity among adolescents, with a focus on identifying emotional triggers and assessing their psychological impact. Utilizing a cross-sectional study design at a university in southern California, data were collected from two adolescents aged 13-18 years. Through surveys and body composition measurements, participants' emotional barriers to weight loss and readiness for change were assessed. The findings underscore the presence of varying degrees of emotional hurdles among adolescents with obesity, including depression, frustration, and …
Food Waste Study At A School District In California, Monica Ibarra
Food Waste Study At A School District In California, Monica Ibarra
Electronic Theses, Projects, and Dissertations
This study is aimed at evaluating food leftovers and wastes among elementary school students by comparing their food preferences for different ethnic cuisines, developing strategies to reduce food waste, and an assessment of quality assurance of food served. Data were collected from a cafeteria at an elementary school located in California. The total number of students served each day at this elementary school was 475. Data were provided by the cafeteria staff after the lunch was served. It was observed that students preferred Chinese food (specifically, Orange Chicken) over Mexican (Beef Chalupas) and American (Turkey with Gravy) where100% of the …
Influence Of Postruminal Casein Infusion And Exogenous Glucagon-Like Peptide 2 Administration On The Jejunal Mucosal Transcriptome In Cattle, Ronald J. Trotta, Kendall C. Swanson, James L. Klotz, David L. Harmon
Influence Of Postruminal Casein Infusion And Exogenous Glucagon-Like Peptide 2 Administration On The Jejunal Mucosal Transcriptome In Cattle, Ronald J. Trotta, Kendall C. Swanson, James L. Klotz, David L. Harmon
Animal and Food Sciences Faculty Publications
We previously demonstrated that postruminal casein infusion and exogenous glucagon-like peptide 2 (GLP-2) administration independently stimulated growth and carbohydrase activity of the pancreas and jejunal mucosa in cattle. The objective of the current study was to profile the jejunal mucosal transcriptome of cattle using next-generation RNA sequencing in response to postruminal casein infusion and exogenous GLP-2. Twenty-four Holstein steers [250 ± 23.1 kg body weight (BW)] received a continuous abomasal infusion of 3.94 g raw corn starch/kg of BW combined with either 0 or 1.30 g casein/kg of BW for 7 d. Steers received subcutaneous injections at 0800 and 2000 …
Voices Of Change: Exploring The Narratives Of Physical Education Stakeholders’ Policy Work In Colorado, Lisa Paulson
Voices Of Change: Exploring The Narratives Of Physical Education Stakeholders’ Policy Work In Colorado, Lisa Paulson
Dissertations
Quality physical education, pivotal for the development of physical, social, and emotional skills for an active and healthy lifestyle (Society of Health and Physical Educators [SHAPE] America, 2014; United Nations Educational, Scientific, and Cultural Organization [UNESCO], 2021), has been globally marginalized, necessitating a heightened focus on policy advocacy engagement (Hardman, 2013; van der Mars, 2021). Policies touch nearly all aspects of physical education (UNESCO, 2014), and a significant barrier is the ‘policy illiteracy’ that contributes to the field’s neglect (van der Mars et al., 2021). Many educators receive little to no policy education, often not identifying as policy actors (Lorusso …
Assessment Of American Tannin-Free Grain Sorghum As Feedstuff For Poultry: Nutrient Composition, Amino Acid Digestibility And Bird Performance, Santiago Sasia
Assessment Of American Tannin-Free Grain Sorghum As Feedstuff For Poultry: Nutrient Composition, Amino Acid Digestibility And Bird Performance, Santiago Sasia
All Dissertations
Given the rising cost of poultry diets, alternative ingredients like sorghum are crucial for maximizing returns without compromising product quality. Sorghum's drought tolerance and adaptability, along with its nutritional profile, make it a viable corn substitute. This dissertation examines the nutrient composition, amino acid digestibility, and performance of poultry fed with American tannin-free grain sorghum. Chapter II evaluates the impact of sorghum-based diets, with or without phytase superdosing, on broiler performance, including body weight, weight gain, feed intake, and feed conversion ratio. Results indicate that sorghum can replace corn without adverse effects on broiler performance. Chapter III explores the partial …
A Process Evaluation Plan For The Nebraska Fetal Infant Mortality Review (Fimr) Program, Mamello Makhele
A Process Evaluation Plan For The Nebraska Fetal Infant Mortality Review (Fimr) Program, Mamello Makhele
Capstone Experience: Master of Public Health
The United States (U.S.) has made substantial progress in reducing fetal and infant mortality, but high rates of infant mortality persist, particularly within minority populations. In Douglas County, Nebraska, racial disparities in infant mortality rates remain a significant issue. In 2019, the infant mortality rate among African American mothers was 14.2 infant deaths per 1,000 live births, compared to 5.7 infant deaths per 1,000 live births among Caucasian mothers.
To reduce fetal and infant mortality in the U.S., the Centers for Disease Control and Prevention along with the Human Resources and Services Administration, fund the Fetal and Infant Mortality Review …
What Are The Potential Drivers Of Nil Perception Among Student-Athletes?, Fred E. Washington
What Are The Potential Drivers Of Nil Perception Among Student-Athletes?, Fred E. Washington
All Dissertations
This dissertation investigated the impact of the NCAA's Name, Image, and Likeness (NIL) policy on student-athletes' college choice. By synthesizing existing academic literature on NIL and college choice models, the study established a comprehensive theoretical framework. The research employed quantitative methods, gathering data through a survey to explore their perceptions and experiences with NIL. The analysis revealed that NIL significantly influenced college selection, with factors such as scholarship type, sport type, and geographic background of the athletes playing crucial roles. Interestingly, most respondents were aware of NIL policies before starting their college search. Demographic insights showed a slight female majority …
Residential Street Trees And Cardiovascular Disease Among Urban-Dwelling Mexican Adults, Christine Campbell
Residential Street Trees And Cardiovascular Disease Among Urban-Dwelling Mexican Adults, Christine Campbell
Walden Dissertations and Doctoral Studies
Cardiovascular diseases (CVDs) are a significant public health burden in Mexico despite national efforts to address traditional risk factors. With growing evidence that elements of nature can improve physical and mental health of people living in cities, this quantitative epidemiological study of secondary data examined the relationship between the presence of street trees in Mexican metropolitan areas and self-reported CVD in adults over age 40. The integrated socio-environmental model of health and well-being provided the conceptual framework for the study. A secondary data analysis was performed using combined individual health data from Mexico’s 2012 National Health and Nutrition Survey and …
Evaluating The Cost Of Gain And Financial Returns Of Cattle Fed Hydroponically Produced Barley Fodder, Lex Peterson
Evaluating The Cost Of Gain And Financial Returns Of Cattle Fed Hydroponically Produced Barley Fodder, Lex Peterson
All Graduate Reports and Creative Projects, Fall 2023 to Present
Hydroponically produced fodder continues to garner attention as a feed source within livestock production. This attention in part is due to a belief that hydroponically produced fodder is more efficient in its use of inputs such as water when compared to conventional feeds. Water efficiency is especially appealing in areas like the Intermountain West region of the U.S where water availability is often constrained. This analysis looks to understand how using hydroponically produced barley fodder to finish steers compares economically to finishing steers on a nutritionally equivalent conventional finishing ration. To do so, a stochastic simulation model is constructed to …
Leveraging Generative Ai For Sustainable Farm Management Techniques Correspond To Optimization And Agricultural Efficiency Prediction, Samira Samrose
Leveraging Generative Ai For Sustainable Farm Management Techniques Correspond To Optimization And Agricultural Efficiency Prediction, Samira Samrose
All Graduate Reports and Creative Projects, Fall 2023 to Present
Sustainable farm management practice is a multifaceted challenge. Uncovering the optimal state for production while reduction of environmental negative impacts and guaranteed inter-generational assets supervision needs balanced management. Also, considering lots of different factors (cost, profit, employment etc), the agricultural based management technique requires rigorous concentration. In this project machine learning models are applied to develop, achieve and improve the farm management techniques. This experiment ensures the resultant impacts being environment friendly and necessary resource availability and efficiency. Predicting the type of crop and rotational recommendations will disclose potentiality of productive agricultural based farming. Additionally, this project is designed to …
Relationship Between The Physical Properties And Oil Binding Capacity Of Fats, Melissa Abigail Marsh
Relationship Between The Physical Properties And Oil Binding Capacity Of Fats, Melissa Abigail Marsh
All Graduate Theses and Dissertations, Fall 2023 to Present
Fats play a significant role in shaping the characteristics of foods, influencing texture, mouthfeel, appearance, and nutritional attributes. An important property of fats is their ability to entrap liquid oil known as oil binding capacity (OBC). Poor OBC of fats frequently leads to shortened-shelf life of foods caused by quality issues due to unwanted chemical and physical changes. In natural nut butters without additives, low OBC often results in a visual oil layer forming at the surface. In filled chocolates such as truffles, pralines, and peanut butter cups this low OBC can result in unwanted textural and visual changes.
The …
Birds, Bees, And The Babies: Study Of The Influence Of Self-Efficacy On Parent-Child Sex Communication, Cassandra M. Craig
Birds, Bees, And The Babies: Study Of The Influence Of Self-Efficacy On Parent-Child Sex Communication, Cassandra M. Craig
All Graduate Theses and Dissertations, Fall 2023 to Present
Previous studies show that parents tend to be uncomfortable discussing sexual topics with their children, such as menstruation, masturbation, and/or condom use. This study offers a look at the part confidence plays in a parent's intentions to talk to their kids about such topics. The results indicated that the confidence parents feel about discussing sexual topics is not related to how much their own parents talked with them about sex. However, the confidence they feel that could be coming from other models, like social media or peers, is related to how much parents intend to talk with their own children …
Microbiome Assembly And Function In The Solitary Mason Bee, Osmia Lignaria (Megachilidae), Bailey Crowley
Microbiome Assembly And Function In The Solitary Mason Bee, Osmia Lignaria (Megachilidae), Bailey Crowley
All Graduate Theses and Dissertations, Fall 2023 to Present
Animal-microbe interactions can influence host biology, ecology, and evolution. The assembly and function of microbes found within animal hosts oftentimes depends on which species are involved. Advances in sequencing technologies have permitted the exploration of host-microbe interactions in a variety of animals, including bees. Early research aimed at understanding the microbiomes of social bees, such as honey bees and bumble bees, found that microbes prevent the spoilage of stored pollen, breakdown indigestible nutrients into smaller molecules available for uptake by the host, and also protect the host from pathogens. When environmental stressors, such as increased temperatures, disrupt the microbiome, the …
An Examination Of The Effects Of Prey Density, Mortality, Nutrients, And Foraging Tradeoffs On A System With Inducible Defenses: An Empirical And Theoretical Approach, Benjamin C. Ralston Daniel
An Examination Of The Effects Of Prey Density, Mortality, Nutrients, And Foraging Tradeoffs On A System With Inducible Defenses: An Empirical And Theoretical Approach, Benjamin C. Ralston Daniel
All Graduate Theses and Dissertations, Fall 2023 to Present
To grasp the functioning and stability of ecosystems, it is important to understand species interactions. With many ecosystems becoming more imperiled from urbanization and anthropogenic influences it is important to understand ways in which species can adapt to rapid changes in their environment. Phenotypic plasticity is one such tool at nature’s disposal to initiate rapid change, where species with the same genetic makeup can have different expressed traits depending on their environment. Inducible defenses are one such form of phenotypic plasticity in which prey can express different levels and forms of defense depending on the threat of predation present in …
Healing Through Caring And Knowledge-Making In Everyday Food Practices Among Lgbtq+ Black, Indigenous, People Of Colour, Elizabeth Grace Wong
Healing Through Caring And Knowledge-Making In Everyday Food Practices Among Lgbtq+ Black, Indigenous, People Of Colour, Elizabeth Grace Wong
All Graduate Theses and Dissertations, Fall 2023 to Present
Three different models are used in this study to understand how everyday food practices carry healing potential through the interwoven process of caring and knowledge-making. Daily food practices reflect a mixture of tradition and modernity— borne out of our roots and our contexts. Anzaldúa’s (1987) Borderland Theory helps us understand how this mixture is made by people who straddle two borders or worlds and contest those confines. Chavez-Dueñas et al.’s (2019) HEART model names strengthening our cultural and familial traditions and roots as part of the broader processes of building cultural consciousness and connection, and engaging in collective healing. Finally, …
Effects Of Winter Ticks (Dermacentor Albipictus) On The Reproduction Of Utah Moose (Alces Alces Shirasi), Samuel D. Robertson
Effects Of Winter Ticks (Dermacentor Albipictus) On The Reproduction Of Utah Moose (Alces Alces Shirasi), Samuel D. Robertson
All Graduate Theses and Dissertations, Fall 2023 to Present
Moose (Alces alces) are the largest and only solitary members of the deer family. The species can be found across many northern regions around the world. Moose are considered to have high intrinsic, recreational and ecological value. In recent years, there have been concerns about declining moose populations in portions of the species circumpolar range. Moose in Utah (Alces alces shirasi) belong to the Shiras subspecies, which is the smallest of the four subspecies found in North America. Utah moose are the southernmost naturally occurring moose population in the world. The Utah Division of Wildlife Resources …
Environmental Physiology Of Medical Cannabis, F. Mitchell Westmoreland
Environmental Physiology Of Medical Cannabis, F. Mitchell Westmoreland
All Graduate Theses and Dissertations, Fall 2023 to Present
Cannabis (Cannabis sativa L.) is increasingly being cultivated for industrial and medical uses. Medical cannabis is grown for cannabinoids and terpenes, compounds that continue to show promising therapeutic potential. Cannabidiol (CBD) and delta-9- tetrahydrocannabinol (Δ9-THC) are the two most common cannabinoids, but more than 150 have been identified in cannabis. The 2018 Farm Bill federally legalized cannabis containing less than 0.3% THC and high-THC medical cannabis is legal in 38 states. There is a need to understand environmental effects on yield and quality to ensure safety and quality for medical use.
The cultivation of medical cannabis is centered around …
Linking Community-Level Food Sovereignty To Subjective Wellbeing: Framing Perspectives On Food Systems In The Upper Yakima River Basin, Alexander W. Theophilus
Linking Community-Level Food Sovereignty To Subjective Wellbeing: Framing Perspectives On Food Systems In The Upper Yakima River Basin, Alexander W. Theophilus
All Graduate Theses and Dissertations, Fall 2023 to Present
Food sovereignty is a framework focused on achieving a wide range of changes in food systems that yield more equitable outcomes for consumers, workers, farmers, and future generations. Food sovereignty is also believed to be an important driver of community wellbeing. However, there is limited research linking perceptions of community-level food sovereignty to subjective wellbeing. Additionally, the complex determinants of food sovereignty are not fully understood. Through two papers linking community-level food sovereignty and subjective wellbeing, I discuss the factors that influence food sovereignty and the impact of food systems on wellbeing in Washington’s upper Yakima River Basin.
In the …
Mental Health Calls For Service During The Covid-19 Pandemic: Examining The Geographic Distribution And Correlates Of Service Requests In Little Rock, Arkansas, Mckayla Bishop
Graduate Theses and Dissertations
In response to the Covid-19 global crisis, the United States implemented social interaction restrictions to curb the infection rate amongst citizens, affecting residents' mental health by adding strain from daily routine change. This study examines how mental health has changed during the pandemic by focusing on geospatial differences of volume and concentration within 311 calls in Little Rock, Arkansas in 2018 and 2020. Our data comes from the City of Little Rock’s open database to construct geospatial maps (n= 155 block groups), along with Census survey data logistic regression models to show differences in community characteristics. Overall, mental health worsened …
Decision-Making In Rats: Effects Of Drug Abuse, Safa Binte Hossain
Decision-Making In Rats: Effects Of Drug Abuse, Safa Binte Hossain
Open Access Theses & Dissertations
Decision-making is a critical cognitive function, often impaired by substance abuse. Understanding the underlying mechanisms in both human and animal models is essential for developing effective treatments. This thesis aims to study approach-avoid decision-making in rats and focuses on the impacts of oxycodone self-administration and alcohol abuse on approach-avoid decision-making.We hypothesize that oxycodone self-administration will alter decision-making in female rats, revealing sex differences and distinct psychometric functions, alcohol habituation will similarly affect decision-making in male rats. The study involved 23 Long Evans rats (11 males and 12 females) for decision-making behavioral study connecting multiple levels of rewards and costs combinations. …
L-Arabinose Induced Overexpression For Crystallographic Analysis Of The Spoiie Protein From Clostridioides Difficile, Danielle M. Maynard
L-Arabinose Induced Overexpression For Crystallographic Analysis Of The Spoiie Protein From Clostridioides Difficile, Danielle M. Maynard
Graduate Theses and Dissertations
The SpoIIE protein plays a crucial role in the sporulation process of Clostridioides difficile, a pathogen responsible for severe gastrointestinal diseases. Understanding the structural and functional aspects of SpoIIE is pivotal for deciphering its role in sporulation and exploring its potential as a therapeutic target. This study investigates the impact of varying concentrations of L-arabinose on the overexpression of SpoIIE in C. difficile, aiming to optimize protein yield and purity for subsequent crystallization and structural determination via X-ray crystallography. Using a recombinant expression system in Escherichia coli, different concentrations of L-arabinose were employed to induce SpoIIE overexpression. Protein purification was …
Alternative Methods For Finishing Beef Cattle: Effects On Performance, Carcass Quality, And Meat Characteristics, Michelle Johnson
Alternative Methods For Finishing Beef Cattle: Effects On Performance, Carcass Quality, And Meat Characteristics, Michelle Johnson
Graduate Theses and Dissertations
The objective of these studies was to evaluate the effects of alternative finishing methods on the live performance, carcass quality, and meat characteristics of beef steers. In study 1, treatments consisted of a conventional feedlot finishing diet with roughage included in the ration (FDLT); a high starch diet fed at 2-2.25% of BW with ad libitum access to bermudagrass pastures (STCH); or a high by-product diet fed at 2-2.25% of BW with ad libitum access to bermudagrass pastures (BYPD). Steers were fed their respective diets once daily and weighed every 28 days until deemed finished. Cattle were then transported and …
Atypical Responses To Sensory Stimuli Or Eating Environments In Children With Autism Spectrum Disorder, Lydia Rockers
Atypical Responses To Sensory Stimuli Or Eating Environments In Children With Autism Spectrum Disorder, Lydia Rockers
Graduate Theses and Dissertations
Children with autism spectrum disorder (ASD) often encounter challenges in processing sensory inputs. Children with ASD may experience feeding difficulties and over- or under- stimulation during food-related activities such as eating or shopping. These have impacts on the health and well-being of individuals with ASD in childhood and throughout their lives. Further research is needed to address the impact of ambient sound levels in a retail or restaurant setting. The main objective of this thesis was to address these gaps by identifying responses to various environmental and food related stimuli. The findings of this research addressed differences in responses between …
Advancements And Case Studies In Modern Dentistry: From 3d Printed Prostheses To Psychological Factors Associated With Oral Health, Hasanuddin, Acing H. Mude, Muhammad Ikbal
Advancements And Case Studies In Modern Dentistry: From 3d Printed Prostheses To Psychological Factors Associated With Oral Health, Hasanuddin, Acing H. Mude, Muhammad Ikbal
Journal of Dentomaxillofacial Science
Advancements and case studies in modern dentistry: From 3D printed prostheses to psychological factors associated with oral health
Risk Analysis Of Bacteria Exposure From Students' Snacks Consumption In Elementary Schools Of Biringkanaya District, Makassar City, Nuralia, Anwar Mallongi, Syamsuar, Agus Bintara Birawida, Apik Indarty Moedjione, Healthy Hidayanty
Risk Analysis Of Bacteria Exposure From Students' Snacks Consumption In Elementary Schools Of Biringkanaya District, Makassar City, Nuralia, Anwar Mallongi, Syamsuar, Agus Bintara Birawida, Apik Indarty Moedjione, Healthy Hidayanty
Journal of Dentomaxillofacial Science
Indonesia is one of the countries that is rich in food. Street food in Indonesia is one of the attractions recognized worldwide. The habit of consuming snacks among schoolchildren is difficult to change, so strict inspection and supervision of snacks sold around elementary schools are needed. This study aimed to determine the risk of exposure to bacteria from the consumption of student snacks in elementary schools in Biringkanaya District, Makassar City. This type of research uses an observational method with a Quantitative Microbial Risk Assessment (QMRA) approach, which aims to calculate the health risk due to exposure to micro bacteria …
The Relationship Between Number Of Remaining Natural Teeth And Nutrient Intake Using The 24-Hour Recall Method On The Female Population Aged Around 50-69 Years, Suhartini, Dwi Prijatmoko, Zahreni Hamzah, Sari Setyaningsih, Happy Harmono, Berlian Prihatiningrum, Yuliana M. Da
The Relationship Between Number Of Remaining Natural Teeth And Nutrient Intake Using The 24-Hour Recall Method On The Female Population Aged Around 50-69 Years, Suhartini, Dwi Prijatmoko, Zahreni Hamzah, Sari Setyaningsih, Happy Harmono, Berlian Prihatiningrum, Yuliana M. Da
Journal of Dentomaxillofacial Science
Background. According to the 2018 Riskesdas, the prevalence of tooth loss increased, from 23,6% at the age of 45-54 years and increased to 30,6% at the age of over 65 years. This shows that as people get older, their ability to chew food decreases, which will affect their nutritional status and quality of life. Objective. Analyzing the relationship between the number of teeth still available and the intake of nutrients, namely, carbohydrates, proteins, and fats and minerals in pre-elderly and elderly people. Method. An analytic experimental study was conducted on 60 people respondents aged 50-69 years with different number …
A Randomised, Parallel-Group, Double-Blind, Placebo-Controlled Phase 3 Study To Determine The Effectiveness Of The Type I Interferon Receptor Antibody, Anifrolumab, In Systemic Sclerosis: Daisy Study Design And Rationale, Dinesh Khanna, Christopher P Denton, Shervin Assassi, Masataka Kuwana, Yannick Allanore, Robyn T Domsic, Christi Kleoudis, John Xu, Eszter Csomor, Caroline Seo, Marius Albulescu, Raj Tummala, Hussein Al-Mossawi, Rubana N Kalyani, Francesco Del Galdo
A Randomised, Parallel-Group, Double-Blind, Placebo-Controlled Phase 3 Study To Determine The Effectiveness Of The Type I Interferon Receptor Antibody, Anifrolumab, In Systemic Sclerosis: Daisy Study Design And Rationale, Dinesh Khanna, Christopher P Denton, Shervin Assassi, Masataka Kuwana, Yannick Allanore, Robyn T Domsic, Christi Kleoudis, John Xu, Eszter Csomor, Caroline Seo, Marius Albulescu, Raj Tummala, Hussein Al-Mossawi, Rubana N Kalyani, Francesco Del Galdo
Faculty, Staff and Student Publications
Objectives: The type I interferon pathway is a promising target for treatment of patients with systemic sclerosis (SSc). Here, we describe the design of a multinational, randomised phase 3 study to Determine the effectiveness of the type I interferon receptor antibody, Anifrolumab, In SYstemic sclerosis (DAISY).
Methods: DAISY includes a 52-week double-blind, placebo-controlled treatment period, a 52-week open-label active treatment period, and a 12-week safety follow-up period. The patient population includes a planned 306 adults with limited or diffuse cutaneous active SSc who satisfied American College of Rheumatology/European Alliance of Associations for Rheumatology 2013 SSc criteria. Use of standard immunosuppressants, …
Age, Sex, And Apoe Gene-Specific Associations Between Dynapenic Obesity And Dementia In A Large Cohort, Zhao Yao, Jie Wang, Tianfang Zhang, Hongjing Ai, Zeinab Abdelrahman, Xiaohong Wu, Daming Wang, Fenfen Chen, Ziwei Zhang, Xiaosheng Wang, Zuyun Liu, Zuobing Chen
Age, Sex, And Apoe Gene-Specific Associations Between Dynapenic Obesity And Dementia In A Large Cohort, Zhao Yao, Jie Wang, Tianfang Zhang, Hongjing Ai, Zeinab Abdelrahman, Xiaohong Wu, Daming Wang, Fenfen Chen, Ziwei Zhang, Xiaosheng Wang, Zuyun Liu, Zuobing Chen
Faculty, Staff and Student Publications
Objective: To investigate the associations between dynapenic obesity and the risk of dementia, and the modifying effects of age, sex, and the APOE gene, using a large population-based cohort.
Methods: 279,884 participants aged 55 and above from the UK Biobank were included. The participants were classified into four categories based on body mass index and hand grip strength: healthy, obesity, dynapenia, and dynapenic obesity. The incident dementia was identified based on linked hospital records and death register data. Cox proportional hazards regression models were used to estimate the associations, followed by age-, sex-, and apolipoprotein E (APOE) gene-stratified analyses.
Results: …
Electrical Stimulation Of The Dorsal Motor Nucleus Of The Vagus In Male Mice Can Regulate Inflammation Without Affecting The Heart Rate, Aidan Falvey, Santhoshi P Palandira, Sangeeta S Chavan, Michael Brines, Robert Dantzer, Kevin J Tracey, Valentin A Pavlov
Electrical Stimulation Of The Dorsal Motor Nucleus Of The Vagus In Male Mice Can Regulate Inflammation Without Affecting The Heart Rate, Aidan Falvey, Santhoshi P Palandira, Sangeeta S Chavan, Michael Brines, Robert Dantzer, Kevin J Tracey, Valentin A Pavlov
Faculty, Staff and Student Publications
Background: The vagus nerve plays an important role in neuroimmune interactions and in the regulation of inflammation. A major source of efferent vagus nerve fibers that contribute to the regulation of inflammation is the brainstem dorsal motor nucleus of the vagus (DMN), as recently shown using optogenetics. In contrast to optogenetics, electrical neuromodulation has broad therapeutic implications. However, the anti-inflammatory effectiveness of electrical stimulation of the DMN (eDMNS) and the possible heart rate (HR) alterations associated with this approach have not been investigated. Here, we examined the effects of eDMNS on HR and cytokine levels in mice administered with lipopolysaccharide …