Digital Commons Network^™

Autophagy And Meiotic Fidelity In C. Elegans, Kaitlin E. Kosinski

Dissertations, Theses, and Capstone Projects

Autophagy is an evolutionarily conserved multi-step recycling process in which cellular material is enclosed in the double membrane-bound autophagosome, which fuses with the lysosome to degrade its contents. Autophagy is essential for development and cellular adaptation to environmental or intracellular stress and is an important regulator of germline stem cell homeostasis in the model nematode C. elegans. We sought to determine if autophagy is important for genome stability during meiosis and found that the core adult C. elegans autophagy genes bec-1, atg-7, unc-51, and atg-18 were all required for proper meiotic development of oocytes. Loss of these …

The Epigenetic Impact Of Dietary Choline On Growth Outcomes Of Children Exposed To Gestational Diabetes Mellitus, Ismail Kadam

Dissertations, Theses, and Capstone Projects

Maternal insulin resistance and hyperglycemia lead to gestational diabetes mellitus (GDM) which can cause fetal hyperinsulinemia, ultimately leading to excessive fetal growth associated with macrosomia and increased adiposity at birth. Increased placental macronutrient transport and epigenetic changes in growth and metabolic genes affected by GDM contribute to fetal overgrowth and can result in complications such as overweight/obesity, insulin resistance/type 2 diabetes, cardiovascular disease risk factors, as well as cognitive impairment later in life. Choline, an essential nutrient, participates in lipid and energy metabolism by providing methyl groups for DNA methylation and thus may overcome the hypomethylation of growth and metabolic …

Meconium: A Potential Means To Predicting Later-Life Cognition, Leah Duran

Dissertations, Theses, and Capstone Projects

Maternal perinatal stress is a commonly experienced, yet chronically undiagnosed condition (CDC, 2010). Literature has suggested that perinatal stress exposure has long lasting implications of the developing child both physically and mentally (Behrman et al., 2007; Hobel et al., 2008; Bowman et al., 2004; Polanska et al., 2017; Van de Bergh et. al, 2020). The use of meconium in the clinical setting has become one that serves a purpose of detection in medical conditions like in utero drug exposure. Using meconium as a predictor for brain behavior, however, is still an emerging concept in the literature. It is quickly gaining …

La Vida: Towards A Motivated Goal Reasoning Agent, Ursula Addison

Dissertations, Theses, and Capstone Projects

An autonomous agent deployed to operate over extended horizons in uncertain environments will encounter situations for which it was not designed. A class of these situations involves an invalidation of agent goals and limited guidance in establishing a new set of goals to pursue. An agent will benefit from some mechanism that will allow it to pursue new goals under these circumstances such that the goals are broadly useful in its environment and take advantage of its existing skills while aligning with societal norms. We propose augmenting a goal reasoning agent, i.e., an agent that can deliberate on and self-select …

Trends And Predictors Of Internet Use For Health-Related Purposes Among Adults In The United States Of America, Paul Ayamah

Dissertations, Theses, and Capstone Projects

This longitudinal study draws on data from the Computer and Internet Use Supplement (CIUS) of the Current Population Survey (CPS) across 2015, 2017, 2019, and 2021 and examines three domains of internet use for health-related purposes: seeking health information online, communicating with healthcare providers via digital platforms, and using electronic health monitoring devices to monitor and transmit health data. The study reveals a 10.60% increase in health-related internet use between 2015 and 2021 among all respondents. Communication with healthcare providers online increased from 21.71% in 2015 to 27.7% in 2021 (p < 0.001), while the use of electronic devices to monitor and transmit health data recorded the least growth of 3.15% in 2014 to 5.93% in 2021 (p < 0.001). Patient communication with a health service provider over the internet demonstrates the most significant increase of 3.74%. Furthermore, this study uncovers disparities between internet use among younger (aged 18-39) and older (aged 75 and older) adults, in which young adults were more likely to seek health information online. From the multivariable logistic regression, factors most likely to contribute to online information seeking include: higher educational attainment, access to multiple digital devices, and access to multiple internet sources.

The study highlights persistent digital divides, particularly among older …

Preliminary Effectiveness Of A One-Week Summer Day Camp For Improving Children’S Health Behaviors And Psychosocial Well-Being Outcomes, Qiaoyin Tan, Yuxin Nie, Paul Son, Renee A. Underwood, Peyton Murray, Callie Hebert, K. Lynn Mckey, Chelsea Hendrick, Amanda E. Staiano, Senlin Chen

Faculty Publications

Purpose: Summer day camp offers children opportunities to grow knowledge and skills, be physically active, and have fun. Compared to healthy children, at-risk children (i.e., overweight, or with obesity and chronic health conditions) typically display less optimal health behaviors and psychosocial well-being, especially during summer months. This study examined the preliminary effectiveness of an American-Diabetes-Association-sponsored summer day camp at improving children’s health behaviors (i.e., physical activity, screen time, diet, sleep) and psychosocial well-being outcomes (i.e., quality of life [QoL], enjoyment, weight-related self-efficacy). Method: The sample consisted of 39 participants, including 19 boys and 20 girls, with majority being overweight (n …

Effects Of Intensive Treatment Of Chinese Women With Gestational Diabetes On The Risk Of Offspring Being Overweight From 3 To 8 Years Of Age, Jing Li, Rui Zhang, Cuiping Zhang, Gongshu Liu, Weiqin Li, Hui Wang, Yijuan Qiao, Zhijie Yu, Gang Hu, Juliana C.N. Chan, Junhong Leng, Xilin Yang

Population and Public Health Science Faculty Publications

No abstract provided.

Assessment Of Novel Protein Ingredient Arthrospira Platensis And Soybean Genotype Amino Acid And Oil Selection Improvements On Broiler Performance For A 28-42 D Feeding Period, Savannah C. Wells-Crofton, Kenneth B. Nelson, Garrett J. Mullenix, Craig W. Maynard, Michael T. Kidd

Poultry Science Faculty Publications and Presentations

Two experiments were conducted to assess the efficiency of including the novel protein ingredient Arthrospira platensis or improved soybean meal in a broiler diet. The first experiment aimed to determine the feeding value of soybean meal produced from varieties of soybeans bred for increased amino acid content (SBAA) and improved oil content (SBO) compared to a conventional soybean variety in an ANOVA design fed to Cobb 500 female broilers for 28–42 d. The SBAA and SBO soybeans contained overall higher amino acid content and lower oligosaccharide content compared to the conventional soybean variety in addition to improved oil quality. The …

Assessing Staff-Youth Interaction Quality: Using The Class To Evaluate Afterschool Programs, Joel M. Hektner, Debarati Kole, Vimbayi Chinopfuktwa, Shawn L. Carlson

Journal of Youth Development

No abstract provided.

Insights Into The Biocompatibility Of Biodegradable Metallic Molybdenum For Cardiovascular Applications-A Critical Review, Janina Mayers, Brianna Hofman, Indie Sobiech, Maria Kwesiga

Open Access Publishing Support Funded Articles

Atherosclerotic cardiovascular disease (ACD) is the leading cause of death worldwide. The gold standard of treatment is the implantation of a permanent stent implant that is often associated with complications such as thrombus formation, vascular neointimal response, and stent fracture, which altogether decrease the long-term safety and efficacy of the stent. Biodegradable metallic materials have become an attractive alternative because of the ability to facilitate a more physiological healing response while the metal degrades. Recently, Molybdenum (Mo) has been considered as a potential candidate due to its excellent mechanical and medical imaging properties. Moreover, the biomedical research studies performed to …

Broken Trust - A $500,000 Lesson In How Banks As Trustees Fail Beneficiaries While Enriching Themselves And While Regulators Ignore The Abuse, Bruce Cahan

Journal of International Business and Law

U.S. households own or control USD $140 trillion (TN).1 Their financial assets under management (AUM) are being managed today through the complex circuitry of global financial markets. Real estate, art and other assets also are being managed. For estate and wealth management planning, for security of long-term asset appreciation and asset protection against bankruptcy, divorce, death, incapacity and exposure of assets to litigation risks, lawyers recommend establishing trusts and rely on the professional expertise, responsibility and ethical clarity of corporate trustees. In the U.S., private trusts typically are formed pursuant to the trust codes of the various states, often modeled …

Access To Audiology Care In Rural And Urban Communities: A Methodology Paper, Molly Whitcomb, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

The ability of those affected by hearing loss to access audiology care is imperative as the effects of unmanaged hearing loss are deleterious, and the prevalence is high. Despite the abundance of individuals affected by hearing loss and the implications of the condition when untreated, barriers to access to care remain primarily unresolved, affecting groups disproportionately. These barriers include knowing when a hearing problem warrants intervention, transportation, geographical barriers, a lack of hearing health care providers, affordability, and insurance coverage. Rural and urban communities are each predisposed to a unique set of social determinants of health, which affect their ability …

Analysis Of The Thermal Aging Kinetics Of Tallow, Chicken Oil, Lard, And Sheep Oil, Yun-Chuan Hsieh, Hao Ouyang, Yulin Zhang, Donyau Chiang, Fuqian Yang, Hsin-Lung Chen, Sanboh Lee

Chemical and Materials Engineering Faculty Publications

Understanding the thermal aging kinetics of animal oils is of vital importance in the storage and applications of animal oils. In this work, we use four different techniques, including UV-Vis spectrometry, viscometry, impedance spectroscopy, and acid–base titration, to study the thermal aging kinetics of tallow, chicken oil, lard, and sheep oil in the temperature range from 120 ◦C to 180 ◦C. The evolutions of the UV-Vis absorbance, dynamic viscosity, electric impedance, and acid titration are discussed with the defect kinetics. The evolutions of the color centers, defects for dynamic viscosity, and electric dipoles follow second-order, first-order, and zero-order kinetics, respectively. …

The Seattle Amyotrophic Lateral Sclerosis (Als) Patient Project Database: Observational, Longitudinal, Dyadic Characterization Of People With Als And Their Partners, Suzanne C. Segerstrom, Edward J. Kasarskis

Neurology Faculty Publications

Introduction: The median survival time in ALS is approximately 3 years, but survival times range from less than a year to more than 10 years and much variance in disease course remains to be explained. As is true for physical outcomes, there is considerable variance in QOL, which is influenced by psychological health, coping, and social support, among other psychosocial factors. The Seattle ALS Patient Project Database (SALSPPD) provides a unique opportunity for researchers to address established and novel hypotheses about disease progression and QOL in ALS.

Methods: The SALSPPD is a longitudinal dataset of people with ALS (n = …

Perceptions Of Low-Income Parents On Kindergarten Readiness: A Qualitative Study, Farrah Woodberry Owens

Electronic Theses and Dissertations

There is a significant amount of research documenting the importance of school readiness and its implication for life-long consequences (Jarrett & Coba-Rodriguez, 2017, 2018; Kang et al., 2017; Malsch et al., 2011). Parents play a critical role in supporting the acquisition of all skills needed to prepare children for school readiness. Readiness refers to being prepared with the necessary skills to access learning (Saracho, 2023). The purpose of this study is to explore the practices and perceptions of low-income parents on kindergarten readiness skills in the Hollywood School District (HSD) as measured by the Kindergarten Readiness Assessment (KRA). Students in …

Environmental Change And Population Dynamics Of Small Mammals In Northern Alaska, Jess K. Steketee

Doctoral Dissertations

Rodent populations at northern latitudes undergo cyclic dynamics characterized by high amplitude interannual fluctuations every 3-5 years. Population cycles have puzzled mammalogists for over a century and disentangling their drivers remains a central goal. Understanding which factors drive rodent populations and how these dynamics might change with warming is essential for predicting the impacts of climate change on arctic ecosystems as herbivore pressure shapes plant community composition, soil nutrient availability and carbon concentrations. My research focused on potential drivers of brown lemming (Lemmus trimucronatus) and tundra vole (Microtus oeconomus) population fluctuations in Arctic Alaska. I combined field techniques with laboratory …

Three Essays On Disability Policy And Employment Of People With Disabilities, Xueting Sun

Doctoral Dissertations

The employment of people with disabilities is substantially and persistently lower than the employment of people without disabilities (Burkhauser et al., 2002; Houtenville & Bach, 2024; Livermore & Honeycutt, 2015). In 2022, using American Community Survey data, the employment-to-population ratio of people with disabilities ages 18-64 was 44.5 percent, compared to 78.9 percent for their counterparts without disabilities (Houtenville & Bach, 2024). This dissertation consists of three essays on disability policy and employment of people with disabilities. The first essay (Chapter 2) explores the effect of the Medicaid expansion, authorized by the Patient Protection and Affordable Care Act, on employment …

Utilization Of Geospatial Distribution In The Measurement Of Study Cohort Representativeness., Keith Feldman, Natalie J. Kane, Stacey Daniels-Young, Bruce Reed, Jessica Welch, Lauren Fitzpatrick, Mark A. Hoffman, Andrea Bradley-Ewing, Elin Grundberg

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: The ability to apply results from a study to a broader population remains a primary objective in translational science. Distinct from intrinsic elements of scientific rigor, the extrinsic concept of generalization requires there be alignment between a study cohort and population in which results are expected to be applied. Widespread efforts have been made to quantify representativeness of study cohorts. These techniques, however, often consider the study and target cohorts as monolithic collections that can be directly compared. Overlooking known impacts to health from socio-demographic and environmental factors tied to individual's geographical location, and potentially obfuscating misalignment in underrepresented …

Special Considerations For The Child With Obesity: An Obesity Medicine Association (Oma) Clinical Practice Statement (Cps) 2024., Suzanne Cuda, Marisa Censani, Valerie O'Hara, Jennifer Paisley, Roohi Kharofa, Rushika Conroy, Brooke Sweeney, Cristina Fernandez Md, Meredith Dreyer, Nancy T. Browne

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) details assessment and management of the child with overweight or obesity. The term "child" is defined as the child between 2 and 12 years of age. Because children are in a continual state of development during this age range, we will specify when our discussion applies to subsets within this age range. For the purposes of this CPS, we will use the following definitions: overweight in the child is a body mass index (BMI) ≥ 85th andpercentile, obesity in the child is a BMI ≥95th percentile, and severe obesity is …

Hereditary Spherocytosis Due To A Novel Variant, P.Q1034x, In The Beta Subunit Of The Spectrin Gene: A Case Report, Emmalee M. Kugler, Akash Patel, Faraz Afridi, Maria I. Scarano, Rafat Ahmed

Department of Emergency Medicine Faculty Papers

Background: Heterozygous pathogenic variants of SPTB cause hereditary spherocytosis (HS) in a quarter of cases. Case report: A 14-day-old male presenting with persistent anemia and hyperbilirubinemia was diagnosed with HS by increased red blood cell osmotic fragility and decreased fluorescence on the eosin-5′-maleimide binding test. For his failure to thrive and hypotonia, genetic sequencing revealed a de novo variant of the SPTB gene (p.Q1034X) on exon 15. This variant is predicted to cause loss of normal protein function either through protein truncation or nonsense-mediated mRNA decay. A variant of uncertain significance (p.R438W) in the chondroitin sulfate synthase 1 (CHSY1) gene …

The Effect Of Woodfiber Additives On Pythium Root Rot And Substrate Microbiome, Isabella Alexandra Borrero

Master's Theses and Capstones

The exponential growth of the greenhouse industry in recent years has led to an increasing demand for economic, “green”, soilless substrates and soilless substrate amendments. To meet this demand, many growers have begun incorporating wood fibers (WFs) into their production systems because they are both economic and renewable. WF’s rise in popularity has motivated an uptick in research focused on understanding how WF amendments affect substrate physical and chemical properties, and how these changes influence plant health, soil-borne disease trends, and microbiome dynamics. Wood fibers have been reported to suppress damping-off of radish caused by Rhizoctonia solani, however, the scope …

Pediatric And Pregnancy-Related Visits At Rural Health Clinics In 2018 Among Medicaid/Chip Enrollees In 20 States, Katherine A. Ahrens Mph, Phd, Zachariah T. Croll, Yvonne Jonk Phd, John Gale, Heidi O'Connor

All Maine Rural Health Research Center Publications

Background: There is limited information on the extent to which Rural Health Clinics (RHC) provide pediatric and pregnancy-related services to individuals enrolled in state Medicaid/CHIP programs. Methods: We used a 100% sample of the 2018 Medicaid Demographic and Eligibility and Other Services Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files for 20 states to estimate pediatric and pregnancy-related services to patients enrolled in state Medicaid/CHIP programs. Results: Among children and young adults enrolled in Medicaid/CHIP in 20 states, around 1 in 10 visited a RHC in 2018. For those living in rural areas, around 1 in 5 visited an RHC …

Control And Management Of Type-Ii Diabetes Among People Living With Hiv (Plwh) Compared To Hiv-Negative Patients And By Clinic Type In The Bronx, Nyc, Aprielle Wills

Dissertations and Theses

ABSTRACT

Control and Management of Type-II Diabetes Among People Living with HIV (PLWH) compared to HIV-Negative Patients and by Clinic Type in the Bronx, NYC

by

Aprielle Wills

Advisor: Heidi E Jones, MPH PHD

Background: The Centers for Disease Control (CDC) estimated that approximately 1.3 million people in the United States (U.S.) were living with an HIV diagnosis by the end of 2021. With advancements of antiretroviral therapy (ART) and improved access to care, HIV has become a chronic condition in the U.S. As PLWH age, they are experiencing higher rates of other chronic conditions, specifically type-II diabetes (type-II …

Examining Well-Being And Healthy Lifestyle Interventions Among Nursing Students Worldwide: A Scoping Review, Christine S. Gipson, Belinda Deal, Michael Skinner

Nursing Faculty Publications and Presentations

Purpose: The purpose of this scoping review was to identify intervention studies related to well-being and healthy lifestyles in nursing students to identify research gaps in the literature for future research. Methods: The review followed the Joanna Briggs Institute (JBI), JBI Manual for Evidence Synthesis, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews checklist. Five databases were searched to retrieve the articles assessed by this review: APA PsycINFO, CINAHL Complete, PubMed, Scopus, and Web of Science. Inclusion criteria included articles with a sample population of nursing students; addressed the well-being, wellness, health, or healthy lifestyle(s) …

From Turf To Turf: Fungal Invasion Of Ascocoryne Turficola In A Northern Michigan Bog, Evan L. Coscarelli-Trott

All NMU Master's Theses

This is the first paper to report Ascocoryne turficola Boud. 1905 (Helotiales: Ascomycota) within the United States. It is an obligate bog fungus native to Europe and Siberia, where it is extremely rare across most of its range. A. turficola appeared at Lily Pond Bog in Marquette, Michigan (87.47º W, 46.59º N) in 2019, almost contemporaneous with anecdotal reports in Minnesota and Ontario. Since 2019, the Lily Pond population has exploded and become the dominant fungus in this bog but has yet to spread to similar bogs nearby. This species is adapted to long distance dispersal and carries the potential …

Drying Techniques For Precooked Hybrid Rice To Ensure Quality Of Instantized Rice, Anne Adhiambo Okeyo, Kaushik Luthra, Justin Siebenmorgen, Alan R. Vazquez, Griffiths Atungulu

Food Science Faculty Publications and Presentations

Background and Objectives

Due to the emergence of new hybrid rice cultivars, rice processors must refine their processing protocols to maintain the production of high-quality products. This is crucial for the instant rice processing industry. Therefore, this study aims to refine current convective heated air-drying processing methods to suit the new hybrid rice cultivars intended for instant rice production. New strategies to dry cooked rice were investigated. These included drying in a stepwise manner with high (230–200°C) and medium (190–160°C) air temperatures and drying at constant high (200°C) and medium (160°C) air temperatures. Changes in quality attributes of two new …

Nrsg 246.50: Health And Illness Of Child And Family Nursing, Ginger M. Sillars

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Hemp Regulates The Fitness Of Corn Earworm (Lepidoptera, Noctuidae) And Its Tachinid (Diptera) Parasitoids, Armando Falcon-Brindis, Raul Villanueva

Entomology Faculty Publications

Pest management on hemp is still in its infancy, and biological control options are limited. Helicoverpa zea (corn earworm) is one of the key pests of hemp cultivated outdoors, especially on cultivars grown for cannabinoids and grain. In a three-year study, we assessed the effect of diet on the performance of H. zea and its tachinid parasitoids. Parasitized (bearing fly eggs) and unparasitized (without eggs) H. zea larvae were fed on hemp flowers or an artificial diet. Five tachinid species parasitized H. zea larvae, but the most abundant species were Winthemia rufopicta (68.8%) and Lespesia aletiae (28.3%). Overall, 55.2% of …

The Web Of Life - Volume 8

be Still

No abstract provided.

To Which We Return, Marianne Koleng

be Still

This work is an attempt to reconcile the vibrance of life as evidenced by the colorful collage and bismuth crystal with death, which is portrayed by a somber skull emerging from an aorta and ventricles of a human heart. Understanding the temporal nature of our existence is key to subtle references to beauty and imperfection latent in the background of this image to cue the idea of beauty in life and death to the viewer.