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Crime Against The Homeless Population: Barriers And Strategies From Washington, Dc Housing Services Case Managers, Stephanie Strianse Oct 2024

Crime Against The Homeless Population: Barriers And Strategies From Washington, Dc Housing Services Case Managers, Stephanie Strianse

Walden Dissertations and Doctoral Studies

Homelessness is a widespread concern across the United States, especially in Washington, DC. The homeless population experiences victimization at alarming rates compared to their housed counterparts; however, these instances of crime against this population are often unreported. The purpose of this generic qualitative study was to explore the barriers to reporting crime against the homeless population and the strategies to reduce those barriers from the perspective of housing services case managers in Washington, DC. Lenoir’s social exclusion theory was the theoretical framework for this study. Data were collected from semi-structured interviews with 11 housing services case managers who work with …


How Does The Reauthorization Of The Farm Bill Impact Snap?, Colleen Heflin, Camille Barbin Oct 2024

How Does The Reauthorization Of The Farm Bill Impact Snap?, Colleen Heflin, Camille Barbin

Center for Policy Research

From 2021 to 2023, food insecurity in the United States increased from 10.2% to 13.5%, and food inflation rose to nearly 20%. The Supplemental Nutrition Assistance Program (SNAP) - the largest food assistance program, in the U.S. is funded and governed by the Farm Bill – a multi-year federal omnibus bill that provides agriculture and nutrition program funding. The 2018 Farm Bill expired on September 30, 2024, and while funding for SNAP has been extended through a Continuing Resolution, program reauthorization is needed. Negotiations on a new Farm Bill have included SNAP proposals to limit state discretion on work requirements …


Effect Of In-Row Spacing On Weed Suppression And Yield Of ‘Covington’ And ‘Monaco’ Sweetpotato, Emmanuel G. Cooper, Stephen L. Meyers, Katherine Jennings, Ashley Adair, Kevin D. Gibson, William G. Johnson Oct 2024

Effect Of In-Row Spacing On Weed Suppression And Yield Of ‘Covington’ And ‘Monaco’ Sweetpotato, Emmanuel G. Cooper, Stephen L. Meyers, Katherine Jennings, Ashley Adair, Kevin D. Gibson, William G. Johnson

Department of Horticulture & Landscape Architecture Faculty Publications

Organic sweetpotato growers have limited effective weed management options, and most rely on in-season between-row cultivation and hand weeding, which are time consuming, are costly, and deteriorate soil quality. Studies were conducted at the Samuel G. Meigs Horticulture Research Farm, Lafayette, IN, and at the Southwest Purdue Agricultural Center, Vincennes, IN, in 2022 and 2023 to determine the effects of in-row plant spacing and cultivar selection on weed suppression and organic sweetpotato yield. The experiment was a split-split plot design, with in-row spacings of 20, 30, and 40 cm as the main plot factor, weeding frequency (critical weed-free period and …


Hidden: A Baker's Dozen Ways In Which Research Reporting Is Less Transparent Than It Could Be And Suggestions For Implementing Einstein's Dictum, Abu Bakkar Siddique, Brian Shaw, Johanna Dwyer, David A Fields, Kevin Fontaine, David Hand, Randy Schekman, Jeffrey Alberts, Julie Locher, David B Allison Oct 2024

Hidden: A Baker's Dozen Ways In Which Research Reporting Is Less Transparent Than It Could Be And Suggestions For Implementing Einstein's Dictum, Abu Bakkar Siddique, Brian Shaw, Johanna Dwyer, David A Fields, Kevin Fontaine, David Hand, Randy Schekman, Jeffrey Alberts, Julie Locher, David B Allison

Children’s Nutrition Research Center Staff Publications

The tutelage of our mentors as scientists included the analogy that writing a good scientific paper was an exercise in storytelling that omitted unessential details that did not move the story forward or that detracted from the overall message. However, the advice to not get lost in the details had an important flaw. In science, it is the many details of the data themselves and the methods used to generate and analyze them that give conclusions their probative meaning. Facts may sometimes slow or distract from the clarity, tidiness, intrigue, or flow of the narrative, but nevertheless they are important …


A Phenomenological Study Of Support To Develop Teacher Efficacy In State Funded Preschool Classrooms, Jennifer Stark Oct 2024

A Phenomenological Study Of Support To Develop Teacher Efficacy In State Funded Preschool Classrooms, Jennifer Stark

Doctoral Dissertations and Projects

The purpose of this qualitative transcendental phenomenology study was to understand the support for teachers in state funded preschool classrooms through the teachers’ lived experiences. The theory guiding this study is Bronfenbrenner’s ecological systems theory as it relates to the role of teacher efficacy in preschool programs and its impact on improving learning environments for children. This study includes a central question and three sub-questions focusing on the support, coaching, and professional learning opportunities provided to educators to improve the learning environment for children in state-funded early childhood classrooms. The setting will include South Carolina state-funded prekindergarten classrooms. The participants …


Investigating The Effects Of Mindful Eating, Self-Compassion, Emotion Regulation, And Spiritual Experience On Compassion Satisfaction And Burnout Among Christian Counselors, Andrew D. Baker Oct 2024

Investigating The Effects Of Mindful Eating, Self-Compassion, Emotion Regulation, And Spiritual Experience On Compassion Satisfaction And Burnout Among Christian Counselors, Andrew D. Baker

Doctoral Dissertations and Projects

It is crucial, in the effort to understand and to be intentional in positively affecting professional quality of life, to examine and balance the impacts of job demands. Nearly four decades ago, Figley introduced the concept of secondary victimization, which when unmitigated leads to compassion fatigue and burnout (Figley, 1988, 1995). Analyses show rates as between 46 and 83% of mental healthcare professionals face unique work environments relating to psychopathological symptoms and lower work satisfaction (Almadani et al., 2022; Lluch et al., 2022; Mollica et al., 2021; Morelen et al., 2022; Stebnicki, 2017; Unjai et al., 2022). Accessing and utilizing …


Developing Resiliency Body Armor Through Psychological And Spiritual Means: How U.S. States' Icac Personnel Cope With Secondary Traumatic Stress, Jameson Lee Denagel Oct 2024

Developing Resiliency Body Armor Through Psychological And Spiritual Means: How U.S. States' Icac Personnel Cope With Secondary Traumatic Stress, Jameson Lee Denagel

Doctoral Dissertations and Projects

Global online child sex abuse and exploitation is rising due to the immense accessibility of the internet, and it takes specially trained and devoted investigators to combat the problem. However, combating these heinous crimes can create traumatic events for investigators, resulting in secondary traumatic stress. This quantitative correlative study examined the psychological and spiritual coping strategies to develop a resiliency body armor concerning Internet Crimes Against Children Task Force personnel (ICAC-TF) working on child sexual exploitation investigations. The theoretical framework combined the concepts of Resiliency Theory, psychology body armor, and spiritual body armor to create resiliency body armor. The study …


Interview With Selena Davila (2024-10-16) Oct 2024

Interview With Selena Davila (2024-10-16)

Latino Virginia Oral History Project

Mahima Sosale interviews Selena Davila from Centerville, Virginia, at VCU. Selena shares her family background, including her parents' young ages at her birth and her close-knit family. She discusses her education trajectory, aiming for law school to focus on family or immigration law. Selena highlights her diverse work experiences, from food service to research and mentoring, and her involvement with LSA, which fosters a sense of community for Latinos at VCU. She reflects on the impact of COVID-19 on her family and the Latino community, emphasizing the importance of representation and open-mindedness towards diverse cultures.


Worship In Life, Worship In Death: Elements Of Worship In A Believer’S Final Days, James William Lawrence Oct 2024

Worship In Life, Worship In Death: Elements Of Worship In A Believer’S Final Days, James William Lawrence

Doctoral Dissertations and Projects

In Isaiah 43:21 (English Standard Version), God declares through his prophet that he created humankind for himself, for them to declare his praises. God created humanity to worship. In the last phase of a believer's life, there is a possibility of not being able to join the rest of the church in corporate worship. This text addresses the question: How does assisting shut-in Protestant Christians with end-of-life worship impact the patient, family, and the concept of dying well? Pastors, chaplains, and ministers from many walks of life have recorded and underlined the importance of worshipful pastoral care in the latter …


Conforming To The Image Of Christ: Addressing Spiritual Immaturity Utilizing Strategic Bible-Based Pastoral Counseling In A Rural Church Context, Leonard Carpenter Iii Oct 2024

Conforming To The Image Of Christ: Addressing Spiritual Immaturity Utilizing Strategic Bible-Based Pastoral Counseling In A Rural Church Context, Leonard Carpenter Iii

Doctoral Dissertations and Projects

Strong and healthy churches are made up of strong and healthy disciples. The ministry context for this qualitative action research project was the Saint Mark Missionary Baptist Church, a predominately Black congregation located in the Pea Ridge community of Brewton, Alabama. The problem was some members at Saint Mark engaged in spiritually immature actions that evoked immature reactions which yielded unhealthy relationships. To address the problem, the researcher developed and implemented the “Strategic Bible-Based Pastoral Counseling Program” (SBPCP), a strategic Christian ministry that provided participants one-on-one pastoral counseling opportunities for the purpose of building up spiritually healthier Christians. SBPCP consisted …


An Ethnically Balanced Male Perspective Towards Police Officers Seeking Mental Health Counseling: A Hermeneutic Phenomenological Study, Arturo Parra Oct 2024

An Ethnically Balanced Male Perspective Towards Police Officers Seeking Mental Health Counseling: A Hermeneutic Phenomenological Study, Arturo Parra

Doctoral Dissertations and Projects

This phenomenological study will aim to understand an ethnically balanced male perspective toward police officers seeking mental health counseling. Police Officers are routinely exposed to stressful and traumatic events, leading to acute and chronic disorders, mental illnesses, suicide ideation, and suicide, as research has indicated. Mental health counseling can play an essential role in intervention into mental health illness, providing critical tools to police officers to handle stress and potential mental illness. However, reluctance among the police community to seek mental health counseling continues to be prevalent. Possible cause for this reluctance are suggested through research as a direct result …


Nurses’ Ability To Provide Diabetes Education In A Hospital Setting, Nicole Ancrum Oct 2024

Nurses’ Ability To Provide Diabetes Education In A Hospital Setting, Nicole Ancrum

Doctoral Dissertations and Projects

Diabetes is a destructive health problem that affects millions of people throughout the United States. Diabetes rates are drastically increasing, and diabetic adults have a higher risk of excessive hospitalization and readmission. One in every four or five hospitalized adult patients has diabetes. Hospitals nationwide are saddled with the responsibility of assessing the need for and supplying diabetic education. Registered nurses’ perception, awareness, and utilization of diabetes education are essential to patients’ ability and willingness to perform diabetes self-management interventions effectively. Meeting inpatient diabetes educational needs requires persistent, innovative strategies appropriate for available resources and staffing models. Nurses play a …


Absent Fathers And The Propensity Of Criminal Behaviors Among Children Later In Life, India Kewanna Holmes Oct 2024

Absent Fathers And The Propensity Of Criminal Behaviors Among Children Later In Life, India Kewanna Holmes

Walden Dissertations and Doctoral Studies

The purpose of the qualitative phenomenological research was to investigate the experiences of young adults raised by one caregiver and how the lack of fathers in the household impacted their decision-making processes concerning engaging in criminal behaviors. The following inquiry guided the research: What are the effects of fatherlessness on decision-making in young adults, and how is it related to criminal behavior? Semi-structured interviews of 15 participants, aged 18 to 26, were used as the primary data collection method. The interview instrument consisted of ten items, and responses were analyzed using coding and thematic analysis. The study's findings revealed several …


Student Loan Policies And Payments During The Covid-19 Pandemic: Closing The Gap Or Widening Inequalities?, Jason Jabbari, Takeshi Terada, Haotian Zheng, Stephen Roll Oct 2024

Student Loan Policies And Payments During The Covid-19 Pandemic: Closing The Gap Or Widening Inequalities?, Jason Jabbari, Takeshi Terada, Haotian Zheng, Stephen Roll

Journal of Student Financial Aid

Student debt was specifically addressed in the federal government’s response to the COVID-19 pandemic through forbearance polices. However, not all individuals were eligible for forbearance, and it is possible that forbearance would leave some feeling further behind. Yet, little is known about student loan debt over the course of the pandemic, especially in relationship to forbearance policies, loan payments, and household financial stability. Leveraging a representative longitudinal survey of households during the pandemic, we use descriptive regression techniques to explore changes in loan balances throughout the pandemic, as well as the relationships among student loan policies, payments, and measures of …


Inter-Provincial Spatial Coupling Of Paddy Fields In China Has Accelerated The Water Consumption, Wenguang Chen, Wencai Zhang, Ming Lei, Ruqian Zhang, Zhenting Zhao, Enyi Xie, Jing Zhao, Xiangbin Kong Oct 2024

Inter-Provincial Spatial Coupling Of Paddy Fields In China Has Accelerated The Water Consumption, Wenguang Chen, Wencai Zhang, Ming Lei, Ruqian Zhang, Zhenting Zhao, Enyi Xie, Jing Zhao, Xiangbin Kong

I-GUIDE Forum

Rice trade has played a significant role in ensuring global rice consumption security. However, the spatial coupling of paddy fields based on rice trade can also transfer ecological environmental effects and threaten the sustainability of local systems. As the largest rice producer and consumer in the world, as well as one of the countries with the lowest per capita water resources, studying the inter-provincial rice flow in China and its water resource utilization efficiency is of great significance for ensuring national rice security and water resource security. Research has found that, China's rice consumption decreased by 11.97 Mt from 2000 …


Social And Environmental Determinants Of Occupation And The Need For An Intersectional Approach To Culturally Meaningful Practice, Diane Smith Oct 2024

Social And Environmental Determinants Of Occupation And The Need For An Intersectional Approach To Culturally Meaningful Practice, Diane Smith

The Open Journal of Occupational Therapy

To provide culturally-centered care to clients and develop interventions that meet the client’s holistic needs, occupational therapists need to consider social and physical environments affecting participation in culturally meaningful occupations. Using a case study, this paper describes the use of the concept of social and environmental determinants of occupation (SEDO) as a necessary strategy to incorporate in clinical practice to determine how SEDO intersect, resulting in occupational justices/injustices that influence access to participation. SEDO are defined as broad (and intersecting) social and environmental factors that increase or limit an individual, community, or population’s ability to participate in culturally meaningful occupations …


The Development, Content Validation, And Clinical Utility Of Mealtime Screening For Schools (Mealss), Karen B. Howarth, Julia M. Guzman Oct 2024

The Development, Content Validation, And Clinical Utility Of Mealtime Screening For Schools (Mealss), Karen B. Howarth, Julia M. Guzman

The Open Journal of Occupational Therapy

Background: This study aimed to determine the initial content validity and clinical utility of Mealtime Screening for School (MEALSS), a new screening tool that measures mealtime participation in students with intellectual and developmental disabilities 5 to 10 years of age.

Methods: To determine the content validity of MEALSS, the researchers recruited five participants identified as pediatric occupational therapists and/or feeding experts to review the MEALSS. Item level content validity index (I-CVI) and scale level validity (S-CVI) were calculated, as well as modified kappa indices to reduce the probability of chance agreement. MEALSS was then revised based on feedback from the …


Guidelines For Conducting Survey Research: Part 1 – Development And Recruitment, Diane Powers Dirette, Rob Lyerla Oct 2024

Guidelines For Conducting Survey Research: Part 1 – Development And Recruitment, Diane Powers Dirette, Rob Lyerla

The Open Journal of Occupational Therapy

No abstract provided.


Pity, Power, And Tolkien’S Ring: To Rule The Fate Of Many, By Thomas P. Hillman, Giovanni Carmine Costabile Oct 2024

Pity, Power, And Tolkien’S Ring: To Rule The Fate Of Many, By Thomas P. Hillman, Giovanni Carmine Costabile

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

No abstract provided.


Antimetastatic Effect Of Nanodiamond-Conjugated Quercetin Against Colon Cancer: An In Vivo Study, Firli Rahmah Primula Dewi, Sephia Tiara Marviella, Sri Puji Astuti Wahyuningsih, A'Liyatur Rosyidah, Vuanghao Lim, Lionel Lian Aun In, Amy Yi Hsan Saik, Bimaji Ariyogo, Mee Lee Looi Oct 2024

Antimetastatic Effect Of Nanodiamond-Conjugated Quercetin Against Colon Cancer: An In Vivo Study, Firli Rahmah Primula Dewi, Sephia Tiara Marviella, Sri Puji Astuti Wahyuningsih, A'Liyatur Rosyidah, Vuanghao Lim, Lionel Lian Aun In, Amy Yi Hsan Saik, Bimaji Ariyogo, Mee Lee Looi

Turkish Journal of Biology

Background/aim: Quercetin (Q) is a compound that can inhibit the growth of cancer cells in the colon; however, to do so, a high dose is needed, requiring a drug delivery system to target cancer endothelial cells directly. This study investigates the potency of nanodiamond-conjugated quercetin (NDQ) as an anticancer drug against colon cancer in Rattus norvegicus induced by N-methyl N-Nitrosourea (MNU). Materials and methods: This study is experimental-based and was designed using a six-group treatment method, namely normal control (KN: not treated by MNU, nanodiamond (ND), or Q); negative control (K–: treated by MNU); positive control (K+: treated by MNU …


Pterostilbene Suppresses Head And Neck Cancer Cell Proliferation Via Induction Of Apoptosis, Tali̇h Özdaş, Si̇bel Özdaş, İpek Canatar, Erdem Kaypak Oct 2024

Pterostilbene Suppresses Head And Neck Cancer Cell Proliferation Via Induction Of Apoptosis, Tali̇h Özdaş, Si̇bel Özdaş, İpek Canatar, Erdem Kaypak

Turkish Journal of Biology

Background/aim: Head and neck cancer (HNC) is one of the most prevalent causes of death worldwide, and the discovery of anticancer agents for its prevention is very important. Pterostilbene (PS) is a trans-stilbene reported to be beneficial in managing various cancers. The objective of the study was to evaluate the cytotoxic, anti-proliferative, pro-apoptotic and anti-migrative effect of PS on HEp-2, SCC-90, SCC-9, FaDu and Detroit-551 cell lines. Materials and Methods: MTT and live/dead assays were employed to assess cell-viability, while cell migration test was performed to evaluate wound healing capacity. The mRNA, protein and intracellular expression level of CASP-3, BAX …


Adipocyte Lipin 1 Expression Associates With Human Metabolic Health And Regulates Systemic Metabolism In Mice, Andrew Lapoint, Jason M. Singer, Daniel Ferguson, Trevor M. Shew, M. Katie Renkemeyer, Hector H. Palacios, Rachael L. Field, Gordon I. Smith, Mai He, Gary J Patti, Samuel Klein, Jonathan R. Brestoff, Brian N. Finck, Et Al. Oct 2024

Adipocyte Lipin 1 Expression Associates With Human Metabolic Health And Regulates Systemic Metabolism In Mice, Andrew Lapoint, Jason M. Singer, Daniel Ferguson, Trevor M. Shew, M. Katie Renkemeyer, Hector H. Palacios, Rachael L. Field, Gordon I. Smith, Mai He, Gary J Patti, Samuel Klein, Jonathan R. Brestoff, Brian N. Finck, Et Al.

2020-Current year OA Pubs

Dysfunctional adipose tissue is believed to promote the development of hepatic steatosis and systemic insulin resistance, but many of the mechanisms involved are still unclear. Lipin 1 catalyzes the conversion of phosphatidic acid to diacylglycerol, the penultimate step of triglyceride synthesis, which is essential for lipid storage. Herein we found that adipose tissue LPIN1 expression is decreased in people with obesity compared with lean subjects, and low LPIN1 expression correlated with multi-tissue insulin resistance and increased rates of hepatic de novo lipogenesis. Comprehensive metabolic and multiomic phenotyping demonstrated that adipocyte-specific Lpin1-/- mice had a metabolically unhealthy phenotype, including liver and …


Intraindividual Discordance Between Remnant Cholesterol And Low-Density Lipoprotein Cholesterol Associated With Incident Stroke: Results From 2 National Cohorts, Cancan Cui, Pingan Li, Yitian Qi, Jiayin Song, Tianjiao Han, Xinyun Shang, Lois Balmer, Chen Sheng, Yining Zha, Zhonghang Xu, Xu Wang, Zhiyuan Wu Oct 2024

Intraindividual Discordance Between Remnant Cholesterol And Low-Density Lipoprotein Cholesterol Associated With Incident Stroke: Results From 2 National Cohorts, Cancan Cui, Pingan Li, Yitian Qi, Jiayin Song, Tianjiao Han, Xinyun Shang, Lois Balmer, Chen Sheng, Yining Zha, Zhonghang Xu, Xu Wang, Zhiyuan Wu

Research outputs 2022 to 2026

BACKGROUND: The atherogenic effect of remnant cholesterol is being increasingly acknowledged. This study aimed to explore the association of discordance between remnant cholesterol and low-density lipoprotein cholesterol with stroke onset using 2 Chinese national cohorts. METHODS AND RESULTS: We studied 11 139 participants from CHARLS (China Health and Retirement Longitudinal Study) and 5993 participants from CHNS (China Health and Nutrition Survey) aged 45 years or older. The discordance between remnant cholesterol and low-density lipoprotein cholesterol was defined using the difference in percentile units (>15 units). There were 988 (8.9%) and 128 (2.1%) stroke events reported during follow-up in the …


Reproduction Has Immediate Effects On Female Mortality, But No Discernible Lasting Physiological Impacts: A Test Of The Disposable Soma Theory, Sharon E Mitchell, Megan Simpson, Lena Coulet, Solenn Gouedard, Catherine Hambly, Juliano Morimoto, David B Allison, John R Speakman Oct 2024

Reproduction Has Immediate Effects On Female Mortality, But No Discernible Lasting Physiological Impacts: A Test Of The Disposable Soma Theory, Sharon E Mitchell, Megan Simpson, Lena Coulet, Solenn Gouedard, Catherine Hambly, Juliano Morimoto, David B Allison, John R Speakman

Children’s Nutrition Research Center Staff Publications

The disposable soma theory (DST) posits that organisms age and die because of a direct trade-off in resource allocation between reproduction and somatic maintenance. DST predicts that investments in reproduction accentuate somatic damage which increase senescence and shortens lifespan. Here, we directly tested DST predictions in breeding and nonbreeding female C57BL/6J mice. We measured reproductive outputs, body composition, daily energy expenditure, and oxidative stress at peak lactation and over lifetime. We found that reproduction had an immediate and negative effect on survival due to problems encountered during parturition for some females. However, there was no statistically significant residual effect on …


First-In-Human Clinical Outcomes With Ng-350a, An Anti-Cd40 Expressing Tumor-Selective Vector Designed To Remodel Immunosuppressive Tumor Microenvironments, Aung Naing, Danny Khalil, Oliver Rosen, D Ross Camidge, Tom Lillie, Rui-Ru Ji, Andrea Stacey, Matthew Thomas, Lee Rosen Oct 2024

First-In-Human Clinical Outcomes With Ng-350a, An Anti-Cd40 Expressing Tumor-Selective Vector Designed To Remodel Immunosuppressive Tumor Microenvironments, Aung Naing, Danny Khalil, Oliver Rosen, D Ross Camidge, Tom Lillie, Rui-Ru Ji, Andrea Stacey, Matthew Thomas, Lee Rosen

Faculty, Staff and Student Publications

Background: Tumor-selective oncolytic viral vectors are promising anticancer therapeutics; however, challenges with dosing and potency in advanced/metastatic cancers have limited efficacy and usage. NG-350A is a next-generation blood-stable adenoviral vector engineered to express an agonist anti-cluster of differentiation (CD)40 antibody without affecting tumor-selectivity and oncolytic potency.

Methods: Intravenous and intratumoral (IT) administration of NG-350A was assessed in a phase Ia/Ib study in patients with metastatic/advanced epithelial tumors (NCT03852511). Dose-escalation was performed separately for intravenous (four dose levels available, each with infusions on Days 1, 3 and 5 of a 57-day treatment period) and IT (single injection on D1 …


Exposure To Per- And Polyfluoroalkyl Substances And Alterations In Plasma Microrna Profiles In Children, Yijie Li, Brittney O Baumert, Nikos Stratakis, Jesse A Goodrich, Haotian Wu, Shelley H Liu, Hongxu Wang, Emily Beglarian, Scott M Bartell, Sandrah Proctor Eckel, Douglas Walker, Damaskini Valvi, Michele Andrea La Merrill, Thomas H Inge, Todd Jenkins, Justin R Ryder, Stephanie Sisley, Rohit Kohli, Stavra A Xanthakos, Marina Vafeiadi, Aikaterini Margetaki, Theano Roumeliotaki, Max Aung, Rob Mcconnell, Andrea Baccarelli, David Conti, Lida Chatzi Oct 2024

Exposure To Per- And Polyfluoroalkyl Substances And Alterations In Plasma Microrna Profiles In Children, Yijie Li, Brittney O Baumert, Nikos Stratakis, Jesse A Goodrich, Haotian Wu, Shelley H Liu, Hongxu Wang, Emily Beglarian, Scott M Bartell, Sandrah Proctor Eckel, Douglas Walker, Damaskini Valvi, Michele Andrea La Merrill, Thomas H Inge, Todd Jenkins, Justin R Ryder, Stephanie Sisley, Rohit Kohli, Stavra A Xanthakos, Marina Vafeiadi, Aikaterini Margetaki, Theano Roumeliotaki, Max Aung, Rob Mcconnell, Andrea Baccarelli, David Conti, Lida Chatzi

Faculty, Staff and Students Publications

BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that persist in the environment and can accumulate in humans, leading to adverse health effects. MicroRNAs (miRNAs) are emerging biomarkers that can advance the understanding of the mechanisms of PFAS effects on human health. However, little is known about the associations between PFAS exposures and miRNA alterations in humans.

OBJECTIVE: To investigate associations between PFAS concentrations and miRNA levels in children.

METHODS: Data from two distinct cohorts were utilized: 176 participants (average age 17.1 years; 75.6% female) from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohort in the United States, and …


Social Determinants Of Health Affect Psychological Distress Among People With Disabilities, Jessica Kersey, Amie Devlin, Sarah Shyres, Emily A Kringle, Ashley J Housten Oct 2024

Social Determinants Of Health Affect Psychological Distress Among People With Disabilities, Jessica Kersey, Amie Devlin, Sarah Shyres, Emily A Kringle, Ashley J Housten

2020-Current year OA Pubs

People with disabilities experience inequitable exposure to social determinants of health (SDOH) that contribute to disparate health outcomes, including psychological distress. There is little research examining which SDOH have the strongest effect on psychological distress among people with disabilities. This leaves healthcare providers and policy makers with insufficient information to make well-informed treatment decisions or allocate resources effectively. We explored the association between SDOH and disability and which factors may moderate the association between disability and psychological distress. Using data from the US Census Bureau's Household Pulse Survey (Phase 3.5), we examined SDOH among people with and without disability (


Interleukin-15 And High-Intensity Exercise: Relationship With Inflammation, Body Composition And Fitness In Cancer Survivors, Morgan J. Farley, Alexander N. Boytar, Kirsten N. Adlard, Chloe E. Salisbury, Nicolas H. Hart, Mia A. Schaumberg, David G. Jenkins, Tina L. Skinner Oct 2024

Interleukin-15 And High-Intensity Exercise: Relationship With Inflammation, Body Composition And Fitness In Cancer Survivors, Morgan J. Farley, Alexander N. Boytar, Kirsten N. Adlard, Chloe E. Salisbury, Nicolas H. Hart, Mia A. Schaumberg, David G. Jenkins, Tina L. Skinner

Research outputs 2022 to 2026

Pre-clinical murine and in vitro models have demonstrated that exercise suppresses tumour and cancer cell growth. These anti-oncogenic effects of exercise were associated with the exercise-mediated release of myokines such as interleukin (IL)-15. However, no study has quantified the acute IL-15 response in human cancer survivors, and whether physiological adaptations to exercise training (i.e. body composition and cardiorespiratory fitness) influence this response. In the present study breast, prostate and colorectal cancer survivors (n = 14) completed a single bout of high-intensity interval exercise (HIIE) [4×4 min at 85–95% heart rate (HR) peak, 3 min at 50–70% HR peak] before and …


Rewiring Our Psychologically Informed Physical Therapy Interventions: Triple Network Model, Immunology, Sex, And Pain Perception, Roberto Sandoval, Mary Lou A. Galantino Oct 2024

Rewiring Our Psychologically Informed Physical Therapy Interventions: Triple Network Model, Immunology, Sex, And Pain Perception, Roberto Sandoval, Mary Lou A. Galantino

Oncology Rehabilitation in Practice

No abstract provided.


Vestibular Rehabilitation Considerations For Chemotherapy-Induced Vestibulotoxicity: A Clinical Perspective, Tabitha Galindo Oct 2024

Vestibular Rehabilitation Considerations For Chemotherapy-Induced Vestibulotoxicity: A Clinical Perspective, Tabitha Galindo

Oncology Rehabilitation in Practice

No abstract provided.