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Astaxanthin Supplementation Does Not Significantly Alter Cognitive Performance Following Mental Fatigue In Females, Gavin A. Barker Jan 2025

Astaxanthin Supplementation Does Not Significantly Alter Cognitive Performance Following Mental Fatigue In Females, Gavin A. Barker

Dissertations

Mental fatigue (MF) is a psychobiological state caused by prolonged periods of demanding cognitive activity, often characterized by impairments to cognitive performance. Astaxanthin (AX) is a naturally occurring antioxidant that can cross the blood-brain barrier and may preserve cognition when presented with a MF challenge. As yet, no studies have yet been conducted in an all-female cohort. This is the first study to investigate 4-weeks of AX supplementation on markers of cognitive performance (reaction time (RT), speed, and responses correct per second (RCS), visual analog scale of mental exertion (VAS-E)) following acute MF. Twenty-five recreationally active female subjects (AX: n …


Comparison Of Post-Exercise Lipid Oxidation Rates Between Lower And 1 Upper-Body Resistance Training In Well-Trained Females, Alyssa L. Parten Jan 2025

Comparison Of Post-Exercise Lipid Oxidation Rates Between Lower And 1 Upper-Body Resistance Training In Well-Trained Females, Alyssa L. Parten

Dissertations

INTRODUCTION: Lipid oxidation (LOx) is a relevant physiological process linked to metabolic health. Despite growing interest in resistance training (RT) as a means to influence substrate utilization LOx responses in females remain poorly characterized, with no study examining whether lower- and upper body RT elicits different LOx patterns during the recovery period following exercise. This distinction may  be relevant because lower-body exercises involves greater fat-free mass (FFM) and energy expenditure,  whereas upper-body exercises recruit less FFM, potentially influencing metabolic effects.

PURPOSE: To  determine if LOx rates after exercise differ between lower- and upper-body RT in well-trained females.

METHODS: Twenty-two females …


University Of Richmond Magazine - Autumn 2025 Jan 2025

University Of Richmond Magazine - Autumn 2025

University of Richmond Magazine

No abstract provided.


Gvsu Undergraduate And Graduate Catalog 2025-2026, Grand Valley State University Jan 2025

Gvsu Undergraduate And Graduate Catalog 2025-2026, Grand Valley State University

Course Catalogs, 1963 - Current

Grand Valley State University 2025-2026 undergraduate and graduate course catalog. Course catalogs are published annually to provide students with information and guidance for enrollment.


Validation Of Nutrition Focus Physical Assessment Via Telehealth, Ann Flickinger Ms, Rd, Ldn, Melissa Faura Rd, Ldn, Shae Duka Mph Jan 2025

Validation Of Nutrition Focus Physical Assessment Via Telehealth, Ann Flickinger Ms, Rd, Ldn, Melissa Faura Rd, Ldn, Shae Duka Mph

Clinical Nutrition Service

No abstract provided.


Manure Handling In Circular Farming: An In Vitro Study Of Fermented Poultry Manure As Unconventional Feed For Ruminants, Dimas Hand Vidya Paradhipta, De Lavida Padma Terrakota, Ali Agus, Andriyani Astuti, Viagian Pastawan, Kharisma Taufiqa Hidayah Jan 2025

Manure Handling In Circular Farming: An In Vitro Study Of Fermented Poultry Manure As Unconventional Feed For Ruminants, Dimas Hand Vidya Paradhipta, De Lavida Padma Terrakota, Ali Agus, Andriyani Astuti, Viagian Pastawan, Kharisma Taufiqa Hidayah

ASEAN Journal on Science and Technology for Development

The development of the poultry industry must consider the principle of circular economy. Therefore, this study aims to develop a method of fermenting poultry manure as a new, unconventional feed, which can support the model of circular farming. Poultry manure obtained from laying hens was mixed with cassava solid waste at a ratio of 7:3 to maintain proper moisture content. The mixed manure fermented for 14 days into a 30 kg silo in triplicate using different additives, namely Lactiplantibacillus plantarum FNCC 0020 at 1 x 105 cfu/g (LP), Bacillus cereus LS2B as proteolytic bacteria at 1 x …


Bagasse Lignin For Single-Used Food Packaging Applications: Uv-Barrier, Antioxidant, Migration And Cytotoxicity, Pawarisa Wijaranakul, Bongkot Hararak, Wanwitoo Wanmoolee, Prapudsorn Wannid, Weerawan Laosiripojana Jan 2025

Bagasse Lignin For Single-Used Food Packaging Applications: Uv-Barrier, Antioxidant, Migration And Cytotoxicity, Pawarisa Wijaranakul, Bongkot Hararak, Wanwitoo Wanmoolee, Prapudsorn Wannid, Weerawan Laosiripojana

Journal of Metals, Materials and Minerals

This study examined PLA biocomposite films made from organosolv lignin extracted from Thai agro-waste, specifically sugarcane bagasse (BG), to assess their suitability for food packaging, focusing on their physical, thermal, optical, UV-shielding, antioxidant, and migration properties. Extracted BG-lignin exhibited free radical scavenging ability with an EC50 value of 400 µg/ml, reducing DPPH absorbance by 50%. PLA composite films with BG-lignin dosage from 0.1 to 1.0 wt.% were successfully fabricated via conventional blown film extrusion. Addition of BG-lignin at 0.5 wt.% and 1.0 wt.% to PLA films decreased UV transmittance from 90% to 30% and 12%, respectively, without compromising optical clarity. …


The Empaths: Nurses At Akuh - Newsletter Quarter 2, 2025, Division Of Nursing Services Jan 2025

The Empaths: Nurses At Akuh - Newsletter Quarter 2, 2025, Division Of Nursing Services

THE EMPATHS: Nurses at AKUH

  • Message from the Chief Nursing Officer
  • Nursing Leadership Roundtable with Trustee Afaf on Quality of Care and Professional Advancement | April 29, 2025
  • Recognition Session with Trustee Afaf Meleis | Honoring the Good Catch Program and Nursing Safety Champions│ April 29, 2025
  • Celebrating Nursing Excellence with Trustee Afaf A Moment of Gratitude for the Hearts of Healthcare
  • Advancing Excellence Across Borders: Highlights from the 2025 AKDN Health System │ May 26 – 28, 2025 │ Nairobi
  • Celebrating International Nurses & Midwives Day │ May 12, 2025
  • Our Midwives - The Heart of Every Beginning! Happy International Midwives Day
  • World Immunization …


Gender-Responsive Reporting And Communication Curriculum, Graduate School Of Media And Communications Jan 2025

Gender-Responsive Reporting And Communication Curriculum, Graduate School Of Media And Communications

The Aga Khan University Prospectuses and Brochures

This curriculum, developed in collaboration with media organisations, women’s professional associations, and civil society groups in East Africa, provides a structured approach to teaching gender-responsive reporting and communication. Covering concepts such as gender analysis, gender-based violence, media representation, and emerging issues including climate change and artificial intelligence, it aims to strengthen journalism education and practice by fostering inclusivity, equality, and balanced reporting


The Aga Khan University Prospectus 2025, The Aga Khan University Jan 2025

The Aga Khan University Prospectus 2025, The Aga Khan University

The Aga Khan University Prospectuses and Brochures

  • Message from the President
  • Message from the Provost & Vice President, Academic
  • About AKU
  • Our Mission, Vision & Values
  • Why AKU?
  • Programmes of Study

    Undergraduate Programmes

  • School of Nursing and Midwifery, East Africa
  • School of Nursing and Midwifery, Pakistan
  • Medical College, East Africa
  • Medical College, Pakistan
  • Faculty of Arts and Sciences, Pakistan
  • Institute for Educational Development, Pakistan
  • Graduate Programmes

  • School of Nursing and Midwifery, East Africa
  • School of Nursing and Midwifery, Pakistan
  • Institute for Educational Development, East Africa
  • Institute for Educational Development, Pakistan
  • Medical College, East Africa
  • Medical College, Pakistan
  • Graduate School of Media and Communications, East Africa
  • Institute for …

Pumpable Hours: Legal Protections For Lactating Individuals Through The Lens Of The Legal Profession, Elise Gonzalez Jan 2025

Pumpable Hours: Legal Protections For Lactating Individuals Through The Lens Of The Legal Profession, Elise Gonzalez

American University Journal of Gender, Social Policy & the Law

The Supreme Court denied women the right to be admitted to the legal profession in 1872. Since this ruling, women have entered the legal profession with force in growing numbers. Today, women comprise nearly 55% of law students across the country and 40% of practicing attorneys in the United States. Despite the growing number of women in the legal profession, women are often reminded of the profession’s sexist history, particularly during a period that is uniquely connected to women—motherhood.


The Effects Of Short-Term, High Dosage Creatine Supplementation On Cognitive Measures Following Mental Fatigue In Healthy Young Adults, Olivia Van Meter Jan 2025

The Effects Of Short-Term, High Dosage Creatine Supplementation On Cognitive Measures Following Mental Fatigue In Healthy Young Adults, Olivia Van Meter

Honors Program Theses

No abstract provided.


Comparative Analysis Of Hydration Status And Microbial Quality Of Tap Water Between Urban And Rural Settings In The Ashanti Region Of Ghana, Marina A. Tandoh, Priscilla Owusu, Claire-Rush N.A. Nkrumah, Veronica Tawiah Annaful, Chris Y. Asare, Samuel Selormi Attu Jan 2025

Comparative Analysis Of Hydration Status And Microbial Quality Of Tap Water Between Urban And Rural Settings In The Ashanti Region Of Ghana, Marina A. Tandoh, Priscilla Owusu, Claire-Rush N.A. Nkrumah, Veronica Tawiah Annaful, Chris Y. Asare, Samuel Selormi Attu

Food Science Faculty Publications and Presentations

Maintaining proper hydration is crucial for human health, physiological functions, and cognitive performance. This study sought to determine the hydration status and the microbial safety of tap water in an urban setting (Kwame Nkrumah University of Science and Technology Campus) and a rural community (Adjamesu) in the Ashanti Region of Ghana. The water safety perception and hydration status of 171 study participants aged 10-61 years were assessed. Six taps were randomly selected at each site in triplicates, resulting in 36 water samples. The microbial quality of the water was assessed by testing for heterotrophic bacteria, coliforms, Staphylococcus aureus, and Salmonella. …


Exploring The Relationship Among Postpartum Depression, Cognitive Distortions, And Relationship Satisfaction, Kylie A. Hastings Jan 2025

Exploring The Relationship Among Postpartum Depression, Cognitive Distortions, And Relationship Satisfaction, Kylie A. Hastings

PCOM Psychology Dissertations

Postpartum depression is the most prevalent psychological disorder experienced following childbirth, impairs daily functioning, negatively impacts child growth and development, and is linked to maladaptive parent-child interactions. Previous research also suggests a link among distorted thinking, depression symptoms, and interpersonal tension. The current study explores the interplay among postpartum depression symptoms, cognitive distortions, and relationship satisfaction among postpartum individuals. Researchers examined how specific thinking errors, including catastrophizing, mindreading, and labeling, are associated with depression symptoms and relational experiences in the postpartum period. Using a quantitative survey design, data were collected from 90 participants using validated instruments: the …


Intimate Partner Violence Victims' Experiences With Civil Legal Interventions, Jessica Brooke Pomerantz Jan 2025

Intimate Partner Violence Victims' Experiences With Civil Legal Interventions, Jessica Brooke Pomerantz

Theses and Dissertations

The court system has become a central part of the societal response to intimate partner violence (IPV) and is a frequently used as a source of help for victims (Cattaneo et al., 2013). Despite the importance of a justice system response to IPV, it is not always accessible or helpful to victims. Past research has demonstrated barriers to IPV victims seeking legal intervention including mistrust of the court system generally, extensive and confusing legal processes and procedures, and failure of the courts to assess more invisible forms of abuse (Calton et al., 2017; Cerulli et al., 2015; Cuomo & Dolci, …


Examining Effects Of A Cultural And Family Resilience Program On Improving Physical Activity And Eating Behaviors Among Overweight Black Adolescents, Mary Quattlebaum Jan 2025

Examining Effects Of A Cultural And Family Resilience Program On Improving Physical Activity And Eating Behaviors Among Overweight Black Adolescents, Mary Quattlebaum

Theses and Dissertations

Black adolescents have higher rates of physical inactivity, lower quality dietary intake, and fewer family meals compared to their White peers. These health inequities place Black adolescents at greater risk for overweight and obesity, as well as long-term health consequences, including chronic disease and early mortality. However, few health promotion programs have been successful in improving health behaviors among Black adolescents and families. Elevated rates of chronic stress, namely racial stress, among Black families may be a prominent obstacle for engagement in and effectiveness of health promotion initiatives. Limited family-based health promotion programs with Black families have incorporated cultural and …


January 2025, Swosu Bulldog Wellness Committee Jan 2025

January 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

January is Thyroid Disease Awareness Month


The Difference A Year Makes: The Admissibility Of Expert Opinion Testimony Under The 2023 Amendment To Federal Rule Of Evidence 702, Daniel J. Capra, Liesa L. Richter Jan 2025

The Difference A Year Makes: The Admissibility Of Expert Opinion Testimony Under The 2023 Amendment To Federal Rule Of Evidence 702, Daniel J. Capra, Liesa L. Richter

Other Faculty Publications

No abstract provided.


Biological Computing From Microscopic To Macroscopic Evolution, Xiaofeng Ding Jan 2025

Biological Computing From Microscopic To Macroscopic Evolution, Xiaofeng Ding

Masters Theses

A unified theory from microscopic to macroscopic DNA-based biological systems is explained in terms of the rule components used when the system size is increased. Even though the eight female rules in each ruleset are provided with an equal probability of the computation-state outcomes, the initial ensemble of the computation states will exponentially settle into one dominant rule that supports the nutrition needed for growth. The remaining seven rules form into two minority groups to provide the biological characteristics of the system's growth from a micro to macroscopic evolution. The object of this study is to prove that such a …


Thermal Inactivation Of E. Faecium On Ground Poultry, Joseph Katz Jan 2025

Thermal Inactivation Of E. Faecium On Ground Poultry, Joseph Katz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Chicken products in grocery stores are contaminated with Salmonella that is ranked number one as a foodborne pathogen, and causes about 1.35 million cases of foodborne illness, 26,500 hospitalizations, and 420 deaths annually. The objective of this study is to determine thermal kinetic parameters of Salmonella surrogate bacteria E. faecium in ground poultry as affected by different temperatures and salt concentrations. The raw chicken was sliced up into a 500 g batch with a total of 6 batches per replicate, ground up in the meat grinder followed by inoculation with E. faecium resistant to 200 ppm Nalidixic Acid. NaCl …


The Use Of An In Chemico Digestibility Assay To Reduce The In Vivo Fish Bioaccumulation Testing Of Nanomaterials, Craig Mchardy, Nathaniel J. Clark, Robert Clough, Richard D. Handy Jan 2025

The Use Of An In Chemico Digestibility Assay To Reduce The In Vivo Fish Bioaccumulation Testing Of Nanomaterials, Craig Mchardy, Nathaniel J. Clark, Robert Clough, Richard D. Handy

School of Biological and Marine Sciences

Currently for engineered nanomaterials (ENMs), there are no alternatives to bioaccumulation testing in fish as prescribed by OECD TG 305. New approaches are being sought, in order to reduce the numbers of animals used and address the ethical concerns associated with the use of vertebrates in such testing. This study aimed to demonstrate the value of an alternative method — the in chemico digestibility assay — as a tool to assess the bioaccumulation potential of ENMs. Titanium dioxide ENMs, or their equivalent bulk form, were incorporated onto a commercial fish diet and the fish digestion process was simulated in vitro …


A Multifactorial Approach To Improve Piglet Health And Survival, Aryeri Stephanie Bardales Castellanos Jan 2025

A Multifactorial Approach To Improve Piglet Health And Survival, Aryeri Stephanie Bardales Castellanos

Electronic Theses and Dissertations

Pre-weaning mortality (PWM) remains a significant challenge in modern swine production systems, particularly in the context of hyper prolific sows. Although genetic selection has successfully increased litter sizes, these advancements have also intensified physiological stress on sows and increased the vulnerability of neonatal piglets. The majority of PWM occurs within the first 72 hours postpartum, with crushing by the sow as the leading cause of death. Additionally, iron deficiency anemia remains one of the most widespread nutritional disorders in piglets, further compromising survival, immune function, and growth. This thesis adopts a multifactorial approach to evaluate two management interventions aimed at …


What Do We Get Out Of Our Entertainment? Empirically Determining The Differences Between Narrative Engagement And Flow Using Video Games, Lars Wagener Jan 2025

What Do We Get Out Of Our Entertainment? Empirically Determining The Differences Between Narrative Engagement And Flow Using Video Games, Lars Wagener

Electronic Theses and Dissertations

Immersion is an important aspect of entertainment media because it both drives the use of media and heightens one’s experience with that media (Nilsson et al., 2016). There are three core aspects of immersion. These aspects are (1) narrative engagement, (2) flow, and (3) enjoyment. This study set out to determine whether these aspects are statistically distinct from one another when observed in video games. The result indicated that these aspects were distinct from one another when examined through a structural equation model. This indicates that creating an overarching immersion variable that combines the different aspects of immersion may not …


The Effects Of Flaxseed Oil-Based Supplementation On Feeding Behavior, Performance, Follicular Dynamics, And Embryo Production In Beef Cattle, Kendal Lynn Green Jan 2025

The Effects Of Flaxseed Oil-Based Supplementation On Feeding Behavior, Performance, Follicular Dynamics, And Embryo Production In Beef Cattle, Kendal Lynn Green

Electronic Theses and Dissertations

This review seeks to provide an overview of fatty acid supplementation in cattle, opening with their structural and functional properties. Nutritional supplementation helps to regulate the precursors and substrates crucial to reproduction. This review aims to examine nutritional supplementation strategies, the role of fatty acids on follicular dynamics, and their impact on embryo production. The base of literature regarding lipid supplementation is vast, with varying results found across studies. Comparing results from prior studies remains difficult as there is a vast range of lipid sources used in beef and dairy animals. The emphasis of this review was placed on evaluating …


Management Strategies To Improve Gastrointestinal Health And Productivity Of Native And Dairy-Derived Steers Fed In Confinement, Becca B. Grimes Francis Jan 2025

Management Strategies To Improve Gastrointestinal Health And Productivity Of Native And Dairy-Derived Steers Fed In Confinement, Becca B. Grimes Francis

Electronic Theses and Dissertations

The objective of this dissertation was to evaluate strategies to mitigate metabolic disorders in confinement fed steers. The first study was conducted on yearling beef steers to investigate the effect of a rumen buffer, calcium magnesium carbonate (CMC), when fed with or without tylosin phosphate (TYL), on growth performance, rumination activity and liver abscess prevalence. Supplementation of a rumen buffer was not an effective alternative to a feed-grade antimicrobial for the control of liver abscesses in beef steers. Supplementation of CMC reduced DMI, thus negatively influencing BW and ADG. No associative effects of CMC and TYL were observed for any …


Impact Of Natural Feed Additives And Monensin Sodium On Growth Performance In Feedlot Cattle, Thiago Lauro Maia Ribeiro Jan 2025

Impact Of Natural Feed Additives And Monensin Sodium On Growth Performance In Feedlot Cattle, Thiago Lauro Maia Ribeiro

Electronic Theses and Dissertations

The objective of this dissertation was to investigate how phytogenic feed additives and a pulse feeding monensin sodium strategy would affect growth performance in the receiving and finishing feedlot phases. Three randomized complete block design feedlot experiments and one pooled analysis were conducted to determine the effects of the feed additives and management strategies used in newly weaned and finishing beef cattle. The objective of these experiments were 1) determine if a blend of capsicum oleoresin, clove essential oil, and garlic essential oil (CCG) influences cattle performance, sera metabolites or health outcomes during the feedlot receiving phase; 2) determine if …


In The Footsteps Of Moose: Using Non-Invasive Techniques To Identify Cause-Specific Calf Mortalities And Evaluate Moose (Alces Alces) Movements Pertaining To Mineral Lick Locations On Ancestral Lands Of The Grand Portage Ojibwe, Anna B. Weesies Jan 2025

In The Footsteps Of Moose: Using Non-Invasive Techniques To Identify Cause-Specific Calf Mortalities And Evaluate Moose (Alces Alces) Movements Pertaining To Mineral Lick Locations On Ancestral Lands Of The Grand Portage Ojibwe, Anna B. Weesies

Electronic Theses and Dissertations

Following a sharp moose (Alces alces; mooz, Anishinaabemowin, Ojibwe language) population decline in northeastern Minnesota during the early 2000s, the Grand Portage Band of Lake Superior Chippewa initiated a long-term moose collaring effort to assess survival and mortality causes. Moose are a culturally important species to the Band, with annual subsistence hunts held on the Reservation and adjacent 1854 Ceded Territory. Continued research guides culturally appropriate management decisions aimed at bolstering calf and adult survival, helping to preserve this moose in Minnesota today and for subsequent generations. Chapter 1 identifies cause-specific calf mortality rates in this multi-predator system using minimally …


Records Of The Wilmore Day Care Center Arc 2025-005 - Finding Aid, Ats Special Collections And Archives Jan 2025

Records Of The Wilmore Day Care Center Arc 2025-005 - Finding Aid, Ats Special Collections And Archives

Finding Aids

No abstract provided.


Minimum Standards For Training In Colorectal Endoscopic Mucosal Resection Among Advanced Endoscopy Trainees, Dennis Yang, Ernesto Robalino Gonzaga, Muhammad Khalid Hasan, Arvind Julius Trindade, Mark Radlinski, Rebecca A Burbridge, Jeffrey Mosko, Pushpak Taunk, Salmaan Jawaid, Mohamed O Othman, David L Diehl, Harshit S Khara, Quin Liu, Srinivas Gaddam, Harry Aslanian, Shailendra S Chauhan, Amrita Sethi, John Poneros, Jason Samarasena, Ali M Ahmed, Uzma D Siddiqui, Dennis Chen, Moamen Gabr, Andrew Y Wang Jan 2025

Minimum Standards For Training In Colorectal Endoscopic Mucosal Resection Among Advanced Endoscopy Trainees, Dennis Yang, Ernesto Robalino Gonzaga, Muhammad Khalid Hasan, Arvind Julius Trindade, Mark Radlinski, Rebecca A Burbridge, Jeffrey Mosko, Pushpak Taunk, Salmaan Jawaid, Mohamed O Othman, David L Diehl, Harshit S Khara, Quin Liu, Srinivas Gaddam, Harry Aslanian, Shailendra S Chauhan, Amrita Sethi, John Poneros, Jason Samarasena, Ali M Ahmed, Uzma D Siddiqui, Dennis Chen, Moamen Gabr, Andrew Y Wang

Faculty, Staff and Students Publications

Background and study aims: Data on colorectal endoscopic mucosal resection (C-EMR) training during advanced endoscopy fellowship remain limited. We aimed to determine the number of procedures required by an "average" advanced endoscopy trainee (AET) to achieve competence in cognitive and technical C-EMR skills.

Methods: AETs from advanced endoscopy training programs (AETPs) were graded on every C-EMR using a standardized assessment tool. Cumulative sum (CUSUM) analysis was used to generate individual and aggregate learning curves to estimate the minimum number of cases required to achieve competence for overall, technical, and cognitive components of C-EMR. AETs completed a self-assessment questionnaire on C-EMR …


Prospective Multicenter Longitudinal Measurement Of Liver Stiffness In School-Age Children With Cholestatic Liver Disease, Benjamin L Shneider, Nathan P Goodrich, Wen Ye, Jean P Molleston, Daniel H Leung, Ronald J Sokol, Laurel Cavallo, Kasper Wang, Pamela L Valentino, Jeffery H Teckman, James E Squires, Shikha S Sundaram, Philip Rosenthal, Rene Romero, Alexander G Miethke, Kathleen M Loomes, Rohit Kohli, Saul J Karpen, Binita M Kamath, M Kyle Jensen, Jorge A Bezerra, Lee M Bass, John C Magee, Children Jan 2025

Prospective Multicenter Longitudinal Measurement Of Liver Stiffness In School-Age Children With Cholestatic Liver Disease, Benjamin L Shneider, Nathan P Goodrich, Wen Ye, Jean P Molleston, Daniel H Leung, Ronald J Sokol, Laurel Cavallo, Kasper Wang, Pamela L Valentino, Jeffery H Teckman, James E Squires, Shikha S Sundaram, Philip Rosenthal, Rene Romero, Alexander G Miethke, Kathleen M Loomes, Rohit Kohli, Saul J Karpen, Binita M Kamath, M Kyle Jensen, Jorge A Bezerra, Lee M Bass, John C Magee, Children

Faculty, Staff and Students Publications

Background and aims: A multicenter prospective longitudinal study of vibration-controlled transient elastography (VCTE) in school-age children with biliary atresia (BA), alpha-1 antitrypsin deficiency (a1-AT) and Alagille syndrome (ALGS) was undertaken to test the hypothesis that there would be measurable disease progression over 2 years.

Methods: Vibration-controlled transient elastography was performed annually for 2 years in children with BA, a1-AT and ALGS.

Results: Valid liver stiffness measurement (LSM) was determined at baseline/second follow-up in 254/180 (71%), 104/58 (56%) and 100/61 (61%) participants (mean elapsed time 2.27 years) with BA, a1-AT and ALGS, respectively. Modeling did not reveal a relationship between LSM …