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The Shorthorn: November 03, 1936 Mar 2025

The Shorthorn: November 03, 1936

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


The Shorthorn: October 27, 1936 Mar 2025

The Shorthorn: October 27, 1936

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


The Shorthorn: March 24, 1936 Mar 2025

The Shorthorn: March 24, 1936

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


The Shorthorn: February 25, 1936 Mar 2025

The Shorthorn: February 25, 1936

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


The Shorthorn: January 29, 1936 Mar 2025

The Shorthorn: January 29, 1936

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


The Shorthorn: October 08, 1935 Mar 2025

The Shorthorn: October 08, 1935

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


Breakfast In Schools: Literature Review, Hannah C. Posey Mar 2025

Breakfast In Schools: Literature Review, Hannah C. Posey

Master of Nutrition and Dietetics

Breakfast is recommended as part of a healthy diet because it is associated with healthier macro and micronutrient intakes, BMI, and lifestyle. Breakfast is also widely promoted to improve cognitive function and academic performance (Hoyland et al., 2009). Yet, according to Hayes and FitzSimons (2024) in the 2021-2022 school year, 51.9 out of every 100 students picked up breakfast, while in the 2022-2023 school year that decreased to 50.9 out of every 100 students. That is a decrease of 1.2 million children for the school year not receiving school breakfast that had the year prior. Hearst et al. (2017) discovered …


The Scarlet – Volume Ciii, No. 9 (March 28, 2025), Scarlet Staff Mar 2025

The Scarlet – Volume Ciii, No. 9 (March 28, 2025), Scarlet Staff

The Scarlet (Student Newspaper) (2011-present)

The March 28, 2025 edition of The Scarlet (est. 1939), Clark University's student-run newspaper. The Scarlet is intellectually and editorially independent of the University.


Understanding The Interplay Between Nutritional Status And Depression Among Community-Dwelling Older Adults, Mary R. Goldsworthy Mar 2025

Understanding The Interplay Between Nutritional Status And Depression Among Community-Dwelling Older Adults, Mary R. Goldsworthy

USF Tampa Graduate Theses and Dissertations

By the year 2050, it is projected that the population of individuals aged 60 years and older will increase by 47 percent, reaching a total of 82 million in the United States. Many older adults experience depressive symptoms, and some never recover from it. Depression is one of the most common psychiatric disorders among older adults. Approximately 3.2% of community-dwelling older adults experience major depressive disorder in a 12-month period, although many more experience clinically significant depressive symptoms, with a recent estimate of 35% based on a global meta-analysis. In addition to physical functioning and depressive symptoms, another domain in …


O The Places Rural Children Will Go…To Get Physical Activity: A Cross Sectional Analysis., Bethany Forseth, Jordan A. Carlson, Adrian Ortega, Chelsea Steel, Brittany Lancaster, Lauren Fitzpatrick, Qianxia Jiang, Ann M. Davis Mar 2025

O The Places Rural Children Will Go…To Get Physical Activity: A Cross Sectional Analysis., Bethany Forseth, Jordan A. Carlson, Adrian Ortega, Chelsea Steel, Brittany Lancaster, Lauren Fitzpatrick, Qianxia Jiang, Ann M. Davis

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Youth living in rural areas have higher risk for overweight/obesity. It is important to understand where these children engage in moderate-to-vigorous physical activity (MVPA) and sedentary time to encourage or intervene on activity in specific locations. This study compared MVPA and sedentary time across locations among children with overweight/obesity in the rural Midwest of the U.S.

METHODS: Participants wore an accelerometer and Global Positioning System tracker over 7-days to collect data on MVPA, sedentary time, and location. Locations were categorized as Home, Home Neighborhood, School, School Neighborhood, and 'Other'. Differences based on school and non-school days were examined.

RESULTS: …


Defining A Management Structure For University Space Analog Research Programs, Scott Van Hoy, Kristen Miller Mar 2025

Defining A Management Structure For University Space Analog Research Programs, Scott Van Hoy, Kristen Miller

Journal of Human Performance in Extreme Environments

To learn how humans can safely and effectively live on the surface of the moon or Mars, missions are conducted on Earth that simulate operations on the surface of other planetary bodies. These missions, called space analog missions, require substantial mission planning and organizational management to ensure safe and effective research and operations. The American Public University System’s Analog Research Group developed and tested management structures and philosophies that enable scalable, replicable, and safe analog missions. This fully online research endeavor’s management and internal organization offers a model that academic institutions and private industry can implement to contribute to space …


Bridging Gaps In Cancer Care: Utilizing Large Language Models For Accessible Dietary Recommendations, Julia A. Logan, Sriya Sadhu, Cameo Hazlewood, Melissa Denton, Sara Burke, Christina A. Simone-Soule, Caroline Black, Corey Ciaverelli, Jacqueline Stulb, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Amy Leader, Adam Dicker, Wookjin Choi, Nicole L Simone Mar 2025

Bridging Gaps In Cancer Care: Utilizing Large Language Models For Accessible Dietary Recommendations, Julia A. Logan, Sriya Sadhu, Cameo Hazlewood, Melissa Denton, Sara Burke, Christina A. Simone-Soule, Caroline Black, Corey Ciaverelli, Jacqueline Stulb, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Amy Leader, Adam Dicker, Wookjin Choi, Nicole L Simone

Department of Radiation Oncology Faculty Papers

Background/Objectives: Weight management is directly linked to cancer recurrence and survival, but unfortunately, nutritional oncology counseling is not typically covered by insurance, creating a disparity for patients without nutritional education and food access. Novel ways of imparting personalized nutrition advice are needed to address this issue. Large language models (LLMs) offer a promising path toward tailoring dietary advice to individual patients. This study aimed to assess the capacity of LLMs to offer personalized dietary advice to patients with breast cancer. Methods: Thirty-one prompt templates were designed to evaluate dietary recommendations generated by ChatGPT and Gemini with variations within …


Effects Of Prebiotic Phytocompound Administration In Gestational Diabetic Dams And Its Influence On Offspring Cognitive Outcomes, Gayathri Jagadeesan, Tushar K Das, Jennifer M Mendoza, Ghalya Alrousan, Maria P Blasco-Conesa, Parimelazhagan Thangaraj, Bhanu Priya Ganesh Mar 2025

Effects Of Prebiotic Phytocompound Administration In Gestational Diabetic Dams And Its Influence On Offspring Cognitive Outcomes, Gayathri Jagadeesan, Tushar K Das, Jennifer M Mendoza, Ghalya Alrousan, Maria P Blasco-Conesa, Parimelazhagan Thangaraj, Bhanu Priya Ganesh

Faculty, Staff and Student Publications

Gestational diabetes mellitus (GD)-induced gut dysbiosis in pregnant mothers may increase the risk of cognitive impairment and neurological disorders in both the mother and offspring as they age. Restoring gut balance could improve cognitive outcomes for both. Despite advancements in GD treatment, side effects have increased, and long-term neurocognitive impacts on offspring born to GD mothers remain underexplored. This study uses a GD mouse model, inducing pancreatic dysfunction in 3-month-old pregnant C57BL/6J mice with Streptozotocin. The efficacy and mechanism of the prebiotic phytocompound green leaf extract (


Assessing Cancer Therapeutic Efficacy In Vivo Using [2h7]Glucose Deuterium Metabolic Imaging, Mario C Chang, Vinay R Malut, Rohit Mahar, Anna Rushin, Marc A Mcleod, Geraldine L Pierre, Indu R Malut, Stephen J Staklinski, Max E Glanz, Mukundan Ragavan, Gaurav Sharma, Manoj Madheswaran, Arshee Badar, Aparna D Rao, Brian K Law, Michael S Kilberg, James H P Collins, Vikram D Kodibagkar, James A Bankson, Ralph J Deberardinis, Matthew E Merritt Mar 2025

Assessing Cancer Therapeutic Efficacy In Vivo Using [2h7]Glucose Deuterium Metabolic Imaging, Mario C Chang, Vinay R Malut, Rohit Mahar, Anna Rushin, Marc A Mcleod, Geraldine L Pierre, Indu R Malut, Stephen J Staklinski, Max E Glanz, Mukundan Ragavan, Gaurav Sharma, Manoj Madheswaran, Arshee Badar, Aparna D Rao, Brian K Law, Michael S Kilberg, James H P Collins, Vikram D Kodibagkar, James A Bankson, Ralph J Deberardinis, Matthew E Merritt

Faculty, Staff and Student Publications

Metabolic imaging produces powerful visual assessments of organ function in vivo. Current techniques can be improved by safely increasing metabolic contrast. The gold standard, 2-[18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging, is limited by radioactive exposure and sparse assessment of metabolism beyond glucose uptake and retention. Deuterium magnetic resonance imaging (DMRI) with [6,6-2H2]glucose is nonradioactive, achieves tumor metabolic contrast, but can be improved by enriched contrast from deuterated water (HDO) based imaging. Here, we developed a DMRI protocol employing [2H7]glucose. Imaging 2H-signal and measuring HDO production in tumor-bearing mice detected differential glucose utilization across baseline tumors, tumors treated with vehicle control or …


Exposure To Compound Climate Hazards Transmitted Via Global Agricultural Trade Networks, Patrick W. Keys, Elizabeth A. Barnes, Noah S. Diffenbaugh, Thomas Hertel, Uris L C Baldos, Johanna Hedlund Mar 2025

Exposure To Compound Climate Hazards Transmitted Via Global Agricultural Trade Networks, Patrick W. Keys, Elizabeth A. Barnes, Noah S. Diffenbaugh, Thomas Hertel, Uris L C Baldos, Johanna Hedlund

Department of Agricultural Economics Faculty Publications

Compound climate hazards, such as co-occurring temperature and precipitation extremes, substantially impact people and ecosystems. Internal climate variability combines with the forced global warming response to determine both the magnitude and spatial distribution of these events, and their consequences can propagate from one country to another via many pathways. We examine how exposure to compound climate hazards in one country is transmitted internationally via agricultural trade networks by analyzing a large ensemble of climate model simulations and comprehensive trade data of four crops (i.e. wheat, maize, rice and soya). Combinations of variability-driven climate patterns and existing global agricultural trade give …


Liver Transplantation In 3 Cholestatic Infants With History Of Covid Exposure, Shruti Sakhuja, Kalyani R Patel, Matthew Goss, Flor M Munoz, Garrett Wortham, Megan Crawford, John A Goss, Nhu Thao Galvan Mar 2025

Liver Transplantation In 3 Cholestatic Infants With History Of Covid Exposure, Shruti Sakhuja, Kalyani R Patel, Matthew Goss, Flor M Munoz, Garrett Wortham, Megan Crawford, John A Goss, Nhu Thao Galvan

Faculty, Staff and Students Publications

The COVID-19 pandemic presents several challenges during pregnancy including thromboembolic complications, direct placental infection, transplacental transmission, and systemic hyperinflammatory state. The liver is the second most commonly affected organ in SARS-CoV-2 infection after the lungs. Mechanisms of liver injury in COVID-19 patients can include: direct viral cytopathic effect, worsening of underlying liver disease, cytokine storm, hypoxic ischemic injury, and cholangiopathy leading to persistent marked cholestasis. Here we describe 3 infants at Texas Children's Hospital with perinatal SARS-CoV-2 exposure with persistent cholestasis and histologic evidence of extrahepatic biliary obstruction suggesting underlying biliary atresia (BA) with some atypical features possibly exacerbated by …


The Shorthorn: February 28, 1933 Mar 2025

The Shorthorn: February 28, 1933

The Shorthorn Newspaper Collection: 1930s

No abstract provided.


Low Income, Abigayle Stearman, Nathan Onoffrey, Ian Mosquera, Melody Pemberton Mar 2025

Low Income, Abigayle Stearman, Nathan Onoffrey, Ian Mosquera, Melody Pemberton

Andrews University Teaching and Learning Conference

Our poster that we created is about low income families and how that can affect students in school. In our poster, we touch on bullying and how low income students are affected by it, we discuss the affects of hunger, how there is a lack of opportunity. Finally, we discuss what kind of school we would create that was the ideal school for low income students.


Benefits Of Nursing Touch In Neonates, Lacy Baldwin, Camila Canedo Muzevic Mar 2025

Benefits Of Nursing Touch In Neonates, Lacy Baldwin, Camila Canedo Muzevic

Scholars Week

This paper explores the benefits of nursing neonatal soothing techniques, focusing on their short- and long-term effects in reducing stress and their influence on development. It emphasizes the nursing role through Kolcaba’s Theory of Comfort in providing proactive non-pharmacological care. Neonates, particularly preemies, face significant amounts of stress in the clinical setting which can impede proper growth and development, as well as immediate well-being. It is part of the nursing duty to alleviate stress and promote comfort. This project analyzes evidence-based research on soothing techniques, including tactile, kinesthetic, gentle human touch, interactive newborn bathing, etc. It demonstrates the positive outcomes …


Bacillus Coagulans 198 And L-Glutamine In Combination Attenuated Intestinal Mucositis In A 5-Fu-Induced Balb/C Mouse Model Via Modulation Of Gut Microbial Community Structure And Diversity, Wei-Jen Chen, Siou-Ru Shen, Wei-Hsuan Hsu, Bao-Hong Lee, Yu-Shan Wei, Hui-Fang Chu, Ming-Chung Tseng, Tang-Long Shen Mar 2025

Bacillus Coagulans 198 And L-Glutamine In Combination Attenuated Intestinal Mucositis In A 5-Fu-Induced Balb/C Mouse Model Via Modulation Of Gut Microbial Community Structure And Diversity, Wei-Jen Chen, Siou-Ru Shen, Wei-Hsuan Hsu, Bao-Hong Lee, Yu-Shan Wei, Hui-Fang Chu, Ming-Chung Tseng, Tang-Long Shen

Journal of Food and Drug Analysis

5-Fluorouracil (5-FU) disrupts intestinal cells and causes dysbiosis in the gut microbiota. This study explores the potential of Bacillus coagulans-198 (BC198) to mitigate gut microbiota imbalance and mucositis caused by 5-fluorouracil. L-glutamine is used to alleviate mucositis, and this study found that BC198 exhibits protective effects on the gut, including maintaining a healthy microbiota and reducing intestinal inflammation, regardless of whether L-glutamine is used in combination. Therefore, it can help reduce the deterioration of the gut environment caused by 5-fluorouracil. BC198 can be provided to cancer patients to prevent severe side effects, thereby improving their treatment outcomes and nutritional …


Protective Role Of Hsian-Tsao Ethanol Extract Against Body Fat, Serum Lipid Profiles, And Hepatic Lipid Profiles In High-Fat Diet-Fed Rats, Ching-Chang Cho, Gow-Chin Yen, Hsin-Yi Lee, Chun-Tse Tsai, Wei-Tang Chang, Chin-Lin Hsu Mar 2025

Protective Role Of Hsian-Tsao Ethanol Extract Against Body Fat, Serum Lipid Profiles, And Hepatic Lipid Profiles In High-Fat Diet-Fed Rats, Ching-Chang Cho, Gow-Chin Yen, Hsin-Yi Lee, Chun-Tse Tsai, Wei-Tang Chang, Chin-Lin Hsu

Journal of Food and Drug Analysis

This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet (HFD)-induced obese rats. Male Wistar rats were administered 0, 100, 200, or 500 mg/kg of 40EEHT, resulting in reduced body weight, total body fat, and hepatic tissue weight after 8 weeks. 40EEHT also decreased adipocyte size, improved lipid profiles, alleviated oxidative stress, and enhanced hepatic antioxidant enzyme activities. Additionally, it regulated fatty acid metabolism by reducing lipogenesis and increasing lipolysis and β-oxidation, suggesting its potential as an anti-obesity dietary supplement.


Xanthohumol As A Potential Therapeutic Strategy For Acute Myeloid Leukemia: Targeting The Flt3/Srpk1 Signaling Axis, Duan-Na Zhang, Wen-Ya Yang, Xiao-Xue Hu, Xiao-Min-Ting Song, Chuan-Jie Guo, Fu Peng, Yu-Zhi Li, Zhi-Xing Cao Mar 2025

Xanthohumol As A Potential Therapeutic Strategy For Acute Myeloid Leukemia: Targeting The Flt3/Srpk1 Signaling Axis, Duan-Na Zhang, Wen-Ya Yang, Xiao-Xue Hu, Xiao-Min-Ting Song, Chuan-Jie Guo, Fu Peng, Yu-Zhi Li, Zhi-Xing Cao

Journal of Food and Drug Analysis

Xanthohumol (XN) is an isoprene chalcone found in hops (Humulus lupulus L.), a food ingredient with a wide range of pharmacological activities. The aim of this study was to reveal the therapeutic effect of XN on acute myeloid leukemia (AML) and the potential underlying molecular mechanism. Through network pharmacology analysis, molecular docking, and HTRF determination, XN was shown to inhibit the kinase activities of FLT3 and SRPK1 by targeting their ATP-binding domains, with IC50 values of 1.51 ± 0.44 μM and 0.37 ± 0.15 μM, respectively. By inhibiting AML cell proliferation, promoting apoptosis, regulating autophagy, and inhibiting …


A Deep Dive Into The Orchard Of Health: Exploring The Anti-Cancer And Anti-Aging Potential Of Apple Polyphenols, Li-Ching Chen, Han-Sheng Chang, Yuan-Soon Ho Mar 2025

A Deep Dive Into The Orchard Of Health: Exploring The Anti-Cancer And Anti-Aging Potential Of Apple Polyphenols, Li-Ching Chen, Han-Sheng Chang, Yuan-Soon Ho

Journal of Food and Drug Analysis

Apples, a ubiquitous and beloved fruit, harbor a treasure trove of bioactive compounds, with apple polyphenols (APs) taking center stage. This review delves into the latest scientific advancements illuminating the anti-cancer and anti-aging properties of APs. We dissect the intricate mechanisms by which APs combat cancer initiation, progression, and metastasis, highlighting their prowess in inducing apoptosis, inhibiting angiogenesis, and modulating cell signaling pathways. Furthermore, we explore the multifaceted ways APs combat aging, including their potent antioxidant and anti-inflammatory actions, DNA protective effects, and ability to modulate cellular processes like autophagy and metabolism. This comprehensive review underscores the therapeutic promise of …


The Effect Of A Combined Aloe Vera And Chlorhexidine Gel On Plaque Index In Children With Cerebral Palsy. Randomized Controlled Clinical Trial), Anwar S. Sabti, Chaza N. Kouchaje, Mhd. Isam H. Agha Mar 2025

The Effect Of A Combined Aloe Vera And Chlorhexidine Gel On Plaque Index In Children With Cerebral Palsy. Randomized Controlled Clinical Trial), Anwar S. Sabti, Chaza N. Kouchaje, Mhd. Isam H. Agha

Arabian Journal of Pediatric Dentistry

Introduction: Background and aim of the research: Oral health and periodontal diseases constitute part of the oral problems in patients with cerebral palsy. Providing oral health care to these patients is extremely difficult due to some of their physical and physical disabilities. Given the existence of a link between oral health and physical health, it was necessary to think about In finding solutions to treat their gingivitis without exerting physical and mechanical effort on the part of the child and his family, and the fact that the use of oral rinses GEL is effective in alleviating gingivitis, it requires …


The Effect Of Sugar-Free Gum On The Salivary Ph Of Children After Consuming Sweetened Milk, Rouaa Zamzam, Nada Bshara Mar 2025

The Effect Of Sugar-Free Gum On The Salivary Ph Of Children After Consuming Sweetened Milk, Rouaa Zamzam, Nada Bshara

Arabian Journal of Pediatric Dentistry

Objectives: This study aimed to monitor the changes in saliva pH after consuming a package of sweetened and chocolate-flavored milk, then studying the saliva pH changes after consuming a sugar-free gum sweetened with xylitol and sorbitol, in children with different additionally dental caries at the age of 3-5 years after conducting a laboratory study of milk to measure its acidity and the amount of added sugars and proteins to it. Materials and Methods: : A chemical analytical laboratory studied the pH and the amount of sugar and proteins added to milk (sweetened and chocolate flavored milk from (Hawa Al …


The Chanticleer, 2025-03-27, Coastal Carolina University Mar 2025

The Chanticleer, 2025-03-27, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.


Laurie Sim Living Memoirs Interview, Laurie Sim Mar 2025

Laurie Sim Living Memoirs Interview, Laurie Sim

Student Missionary Stories

Laurie Sim, a Southern alumna, shared her experiences as a student missionary in Aranyaprathet, Thailand. She served in refugee camps during the Cambodian refugee crisis, providing nursing care and assisting with nutrition programs. Inspired by her mother’s nursing career and her brother’s mission stories, she overcame initial fears and found purpose in helping others. Her time as a student missionary shaped her both spiritually and professionally, influencing her future missionary and advocacy work.

Thailand, located in Southeast Asia, shares borders with Myanmar, Laos, Cambodia, and Malaysia. Known for its rich cultural heritage, Thailand blends Buddhist traditions, monarchy, and modern influences. …


Introducing Kids To Cultural Cuisines, Maggie Mckay, Rachel Finn Mar 2025

Introducing Kids To Cultural Cuisines, Maggie Mckay, Rachel Finn

Parent-ish Podcast

While it can be easy to lean on your tried and true, family-favorite recipes, introducing children to diverse cuisines is a wonderful way to expand their understanding of different cultures while also trying new foods. As parents, we have the unique opportunity to use food as a tool for education and connection. Rachel Finn, chef/educator at Children's Mercy Kansas City, discusses how to involve kids in the process and make discovering new cuisines fun and nutritious for the whole family!

Click here to stream the podcast episode.


A Study To Identify The Causal Rare Genetic Variants In Primary Open And Closed Angle Glaucoma, Pseudoexfoliation Syndrome, And Associated Glaucoma, Suganya K Mar 2025

A Study To Identify The Causal Rare Genetic Variants In Primary Open And Closed Angle Glaucoma, Pseudoexfoliation Syndrome, And Associated Glaucoma, Suganya K

Theses and Dissertations

BACKGROUND: Glaucoma is the second most common cause of blindness globally typically diagnosed with a triad of clinical symptoms of increased intraocular pressure (IOP) with associated optic disc, optic nerve head (ONH) changes, and visual field defects. Genetic and environmental factors are some of the strong aetiology factors for glaucoma and identification of these factors has a potential implication in the management of the disease and its outcome. There is a paradigm shift towards understanding the genetics of glaucoma, wherein the variants in the nuclear, mitochondrial genome and other regulatory regions are being identified as contributing risk factors.

METHODOLOGY AND …


Efficacy Of Baits And Lures For Weasel Detection, Scott M. Bergeson, Roland Kays, David S. Jachowski, Courtney D. Anderson, Chad R. Williamson, Ashley Burket, Joseph W. Butfiloski, Amanda E. Cheeseman, Stacy Cotey, Catherine C. Dennison, John D. Erb, Zach J. Farris, Michael L. Fies, Michael J. Joyce, Colleen Olfenbuttel, Blake Sasse, Lisa M. Smith, Joshua A. Tabora, Marketa Zimova Mar 2025

Efficacy Of Baits And Lures For Weasel Detection, Scott M. Bergeson, Roland Kays, David S. Jachowski, Courtney D. Anderson, Chad R. Williamson, Ashley Burket, Joseph W. Butfiloski, Amanda E. Cheeseman, Stacy Cotey, Catherine C. Dennison, John D. Erb, Zach J. Farris, Michael L. Fies, Michael J. Joyce, Colleen Olfenbuttel, Blake Sasse, Lisa M. Smith, Joshua A. Tabora, Marketa Zimova

Michigan Tech Publications

Small mustelids are difficult to survey due to their low density and cryptic nature. Population status of North American weasels (Mustela erminea, Mustela nivalis, and Neogale frenata) are believed to be in decline, but there are no standardized monitoring protocols to evaluate their status. To support weasel monitoring, we compared the attractiveness of various combinations of baits and lures to weasels in sites located throughout the eastern and central USA. We baited a total of 122 clusters of 4 camera traps, across 14 states, with random combinations of 4 baits and 3 scent lures in the winters of 2022 and …