Digital Commons Network^™

Prooxidant Effect Of Uric Acid On Human Leukocytic Dna: An In Vitro And Ex Vivo Study, Yim Tong Savio Szeto, Vincy Sze Wing Li, Yuen Lam Pon

Turkish Journal of Biology

Background/aim: Uric acid is a major contributor to the total antioxidant capacity of human plasma. However, this endogenous substance’s antioxidant and prooxidant properties have not yet been reported.

Conclusion: In this study, the comet assay was employed in vitro to determine the effect of uric acid on DNA damage in human lymphocytes and leukocytic DNA damage in hyperuricemia patients with and without renal failure.

Results: DNA damage in lymphocytes occurred at uric acid concentrations of ≥600 μM. Adding catalase to the uric acid solution diminished the damaging effect, indicating that hydrogen peroxide mediated the prooxidant activity. Moreover, …

Kitchensync: A Pantry And Recipe Companion, Tyler Son, David Tran, Chris Nederhoed

Electrical Engineering and Computer Science Student Publications

Why KitchenSync?Global household food waste: > 1.3 billion tons per year—home cooks need better visibility on what’s on hand. Fragmented toolchain: recipe apps, grocery lists, and inventory trackers all separateTime‐pressed users: busy families, students, professionals struggle to plan meals efficiently

Intimacy Versus Isolation In Adults With Intellectual Or Developmental Disabilities: An Educational Video-Series For Caregivers, Aubrey Lynn Brinkley

Student Capstone Papers

Caregivers of care-recipients with intellectual or developmental disabilities (IDD) do not have sufficient resources to assist their care-recipients with the adult developmental stage of intimacy versus isolation. This capstone considers the occupational and developmental impacts that growing individuals with IDD face, namely the developmental stages including healthy relationships, sexual safety, and intimacy. The literature review covers the scientific, statistical, and historical importance of this developmental milestone. Varied opinions and needs that surround the subject of intimacy and healthy relationships for adults with IDD were considered. Sexual abuse statistics were highlighted. A multitude of feedback from organizations, personal caregivers, scientists, psychologists, …

A Comprehensive Diabetes Symptom Management Program For Independent Living Facilities, Brooke A. Foster, Mary Jan Greer

Spring 2025 OTD Capstone Symposium

This project aimed to support older adults with diabetes mellitus (DM) and pre-diabetes in independent living facilities through a comprehensive symptom management program. Implemented at Coastal Heights Senior Living in Costa Mesa, California, the program focused on improving overall education and self-management of DM symptoms, emphasizing foot care, physical activity, and nutrition. Using a client-centered approach and the Person-Occupation-Environment-Performance model, participants engaged in group and individual sessions over an eight-week period. Outcomes showed an increased understanding of DM, improved self-care behaviors, and enhanced ability to manage symptoms independently, supporting aging in place and promoting overall wellness.

Heredity, Chris Burley, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Heredity is the sum of biological processes that result in the transmission of genetic traits from parents to their offspring, making each individual unique. Through the transmission of genetic traits, heredity is responsible for each individual’s genotype, as well as his or her phenotype. The genes that are passed down from generation to generation have a considerable influence on psychological characteristics including intelligence, personality, mental health, and patterns of behavior. However, when considering psychological characteristics passed down through heredity, it is vital that environmental aspects are also considered.

All Stressed Out: An Investigation On The Effects Of Environmental Stressors On The Northern Leopard Frog (Rana Pipiens), Ella C. Wittmuss

Honors Thesis

Corticosterone (CORT) is the primary glucocorticoid in many vertebrates, including mammals, birds, reptiles, and amphibians. When an organism is exposed to external or internal stressors, CORT levels often increase (Rich & Romero, 2005; Titon et al., 2021). An increase in CORT can cause adverse physiological effects such as slower growth, malformations in different parts of the body, and specific blood sugar diseases such as diabetes (Glennemeier & Denver, 2002; Tarlow &Blumstein, 2007). CORT levels are indicators of survival, growth, and reproduction in larval amphibians. Many species, including our model organism, the Northern Leopard Frog (Rana pipiens), are often subjected to …

Spectrum Of Congenital Anomalies Detected Through Anatomy Ultrasound At A Referral Hospital In Ghana, Alim Swarray-Deen, Morgan Yapundich, Sarah Boudova, Kwaku Doffour-Dapaah, Jeff Osei-Agyapong, Perez Sepenu, Alex K. Boateng, Teresa A. Mensah, Patrick Anum, Nana Essuman Oduro, Theophilus Adu-Bredu, Promise E. Sefogah, Jerry Coleman, Samuel A. Oppong

Department of Obstetrics and Gynecology Faculty Papers

BACKGROUND: Africa has a high burden of congenital anomalies due in part to limited preconception care, infections, and environmental exposures. However, the true prevalence of congenital anomalies is unclear because of insufficient access to prenatal diagnostic services. We aimed to determine the rate of congenital anomalies, and characterize the anomalies detected prenatally at a referral hospital in Ghana.

METHODS: We performed a four-year retrospective review of all fetal anomaly ultrasounds performed and congenital anomalies detected from January 1st, 2020, to December 31st, 2023, at Korle Bu Teaching Hospital, Accra, Ghana. Data were extracted from the electronic database on maternal age, …

Midlife Physical Changes, Kirsten Horne, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Aging occurs at different rates in individuals. These rates are influenced by factors including genetics, lifestyle, and health. Midlife is considered to be the central period of one’s life, consisting of individuals who are approximately 45 to 65 years of age, although some researchers suggest midlife consists of individuals who are 40 to 65 years of age. There are a variety of changes that occur throughout life. However, a majority of the changes that occur during midlife are considered to be normative physical changes. The physical changes in midlife include but are not limited to changes in appearance, senses, muscles, …

Comparing Out-Of-Pocket Costs And Health-Related Quality Of Life Between Sodium-Glucose Cotransporter 2 Inhibitors And Glucagon-Like Peptide-1 Receptor Agonists In Patients With Type 2 Diabetes, Sisi Hu, Preeti P. Zanwar, Tara Jenkins, Rajkumar J. Sevak, Bhaskara R. Jasti

Pacific Faculty Work

Purpose: To compare the impact of sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor), glucagon-like peptide-1 receptor agonist (GLP-1 RA), with or without metformin, on out of pocket and total prescription expenditure and health-related quality of life (HRQoL) for patients with type 2 diabetes mellitus (T2DM). Patients and Methods: This observational study utilized 2017– 2021 Medical Expenditure Panel Survey (MEPS) data from patients with T2DM (≥ 18 years) on SGLT2 inhibitor, GLP-1 RA, with or without metformin, from payer and self-perspective. HRQoL was assessed using physical (PCS) and mental component summary (MCS) scores based on Veterans Rand 12. This study estimated survey-weighed …

Cottonseed Polyol-Based Composite Evaluated With Inorganic Fillers, Kehinde Esther Ayodeji

Electronic Theses & Dissertations

Composites are extensively utilized as raw materials in an industry. In this study, we synthesized polymer composites, cottonseed oil polyol-based composites, incorporating inorganic fillers. This synthesis process involves the epoxidation of cottonseed oil followed by ring opening. Various characteristics of the polyol, such as the presence and quantity of hydroxyl groups (-OH), iodine value, and viscosity, and Fourier transform infrared spectroscopy (FTIR) was determined. The composite samples were prepared by mixing different fillers (SiO₂, TiO₂, and Al₂O₃). These composite formulations underwent three-week processing period, with each filler being incorporated at room temperature. …

Caregivers’ Satisfaction With And Perceived Cultural Sensitivity Of A Modification Of A Child Injury Prevention Program For Spanish-Speaking Families, Karen Padilla

Honors Theses

Unintentional injuries are a leading cause of death among children in the United States. Caregivers play a critical role in reducing children’s risk of injury by adopting appropriate supervision behaviors and engaging in safety-proofing practices. The Supervising for Home Safety (SHS) program is a video-based intervention developed to increase caregiver supervision for children ages 2–5 by targeting beliefs about injury vulnerability, injury preventability, and self-efficacy for implementing safety precautions. While SHS has demonstrated effectiveness in English-speaking populations, no research has examined its adaptation and impact among Spanish-speaking caregivers. This study aimed to examine caregivers perceived cultural sensitivity and satisfaction with …

Attachment Theory: John Dollard And Neal Miller, Carla Cabrera, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

No abstract provided.

Bio-Physiological Development During Adulthood, Maria Boix Braga, Charles J. Golden, Lisa K. Lashley

Essays in Developmental Psychology

Defining adulthood, and what the criteria truly is to be able to consider oneself an adult, varies from culture to culture. Biologically, adulthood can also be defined as the period in which full physical and intellectual maturity has been attained. It is a period that is defined slightly differently depending on the source, but it is agreed that it tends to be considered the life period between ages 18 and 60. However, the definition of adulthood can have varying legal and sociocultural factors as well. For example, the legal definition of an adult is a person who has reached the …

Parental Influence, Justin Burgess, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

An adequate level of parenting—providing enough nutrition, shelter, exposure to language and peers, or not harshly punishing children (punching, kicking, striking with a weapon)—seems to not have a long-term effect on cognitive development in children. Twin and adoption studies have found that intelligence is accounted for almost entirely by genes and nonshared environment, which includes peers, teachers, and unique experiences. However, there are parenting styles and types of home environments that are correlated with better school performance, stronger school engagement, and more words spoken at certain ages.

Nutrition And Growth, Chris Burley, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

From a child’s embryonic development in the womb to adulthood, nutrition plays a key role in physical, mental, and social growth and development. Throughout the lifespan, proper nutrition and growth are essential to living a long, healthy life. Nutrition is particularly important in the developmental period.

Detection Of Mthfr C677t Genotyping For Spina Bifida Defects Using Arms-Pcr Technique, Halah Kamal Al-Qazzaz, Zahraa F. Al-Khero, Hameed Husham Hameed

Baghdad Science Journal

Neural tube defects (NTDs) are complex structural deformities in newborn infants. These defects are caused by a blend of genetic and environmental factors in the abnormal phenotype. The current study aims to determine the genetic variation polymorphism for methylenetetrahydrofolate reductase (MTHFR) C677T rs180133 genotyping and to detect single nucleotide polymorphisms (SNPs) in a DNA sample of Spinal Bifida (SB) and compare it with control newborn children. Blood samples were collected from newborns (50 children under one year old) (25 cases of spinal bifida (SB) and 25 controls). The DNA was extracted and amplified by the tetra ARMS-PCR technique (Amplification Refractory …

Distinct Adipose Progenitor Cells Emerging With Age Drive Active Adipogenesis, Guan Wang, Gaoyan Li, Anying Song, Yutian Zhao, Jiayu Yu, Yifan Wang, Wenting Dai, Martha Salas, Hanjun Qin, Leonard Medrano, Joan Dow, Aimin Li, Brian Armstrong, Patrick T Fueger, Hua Yu, Yi Zhu, Mengle Shao, Xiwei Wu, Lei Jiang, Judith Campisi, Xia Yang, Qiong A Wang

Children’s Nutrition Research Center Staff Publications

Starting at middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) in visceral fat undergo extensive adipogenesis during middle age. Thus, despite the low turnover rate of adipocytes in young adults, adipogenesis is unlocked during middle age. Transplantations quantitatively showed that APCs in middle-aged mice exhibited high adipogenic capacity cell-autonomously. Single-cell RNA sequencing identified a distinct APC population, the committed preadipocyte, age-enriched (CP-A), emerging at this age. CP-As demonstrated elevated proliferation and adipogenesis activity. Pharmacological and genetic manipulations indicated that leukemia inhibitory factor receptor signaling was …

Comparative Efficacy And Acceptability Of Interventions For Universal, Selective And Indicated Prevention Of Eating Disorders: Study Protocol For A Systematic Review And Network Meta-Analysis, Sandra Schlegl, Felicitas Hirler, Andreas Gerich, Mikkel Højlund, Eric Stice, Tracey Wade, Denise Wilfley, James Downs, Ulrich Voderholzer, Jasmine Perry, Verena Haas, Marco Solmi, Christoph Correll

2020-Current year OA Pubs

BACKGROUND: Eating disorders (EDs) are severe psychiatric conditions, with prevalence rates ranging from 5.5 to 17.9% in women and 0.6 to 2.4% in men. EDs carry a high risk of chronicity and mortality, highlighting the need for effective prevention strategies. Primary prevention can target the entire population (universal), high-risk groups (selective), or individuals with early signs (indicated). Despite substantial research, prior reviews often show limitations, such as single-author data extraction, lack of quality assessment, reliance on endpoint data, exclusion of obesity prevention programs, or outdated findings. No review has yet evaluated the comparative effectiveness of multiple interventions across risk groups. …

The Relationship Between Psychological Distress, Work Burnout, And Firearm Ownership Among Correctional Officers, Corey Tolliver

Academic Festival

Introduction. This study examines the relationship between psychological distress, work burnout, and firearm ownership among correctional officers. Methods. Using secondary cross-sectional data, we investigated psychological distress, work burnout, and the impact of firearm ownership among 211 correctional officers (COs). Results. Psychological distress is alarmingly high across all racial/ethnic groups, with the vast majority classified as likely to have a severe mental disorder. White COs exhibit the highest mean distress scores. Over half of the COs enrolled reported owning a firearm (54.5%). Those who reported having to own a firearm tended to have higher work burnout compared to those who never …

Platform Wars In Maternal Health: What Huel’S Success On Shopify And Amazon Teaches Us About Building Trust And Loyalty, Autumn Marshall

Academic Festival

The United States maintains a poor ranking in maternal mortality rates among developed nations, supporting traditional maternal system mistrust to increase. This creates an increased opportunity for maternity women to seek help from wellness brands. The Amazon and Shopify presence of Huel enabled me as a Marketing Professional, to study how the two digital platforms impact health product purchasing decisions. My research utilizes a comparative platform analysis based on the product features, Health Belief Model and Brand Equity Theory to gain insight for customer experience, SEO strategy, product discoverability and brand storytelling. The study reveals that Amazon provides extensive market …

The Nicu Nurse’S Aptitude In Teaching Neuroprotective Care To Caregivers Of Neonates, Lucy Bradley

GS4 Student Scholars Symposium

No abstract provided.

Moomoo Care Program, Shelby Knoble

Research & Creative Achievement Day

Set on a family farm, the Moo-Moo Care Program is a hands-on, multi-day recreational program designed to teach youth about dairy cattle care. As part of my RTTR 203 final project, I created a daily schedule, goals and objectives, a Gantt chart for task organization, marketing materials, and an evaluation form.

Within this program, participants will engage in at least six hours of structured farm activities each day. Through interactive lessons and hands-on demonstrations, participants will learn key aspects of dairy cattle care, including feeding, milking, and how to maintain a clean environment. Participants will practice proper calf grooming skills …

Stay Fit, Stay Safe: Sports Safety For Community-Dwelling Older Adults, Kierra A. Pickard, Lauren G. Cahalan, Allie Sonnleitner, Hanna G. Crabtree, Emily J. Myszewski, Claire R. Privatt, Maya L. Vosters

Research & Creative Achievement Day

Purpose: With the growing older adult population, defined as 65 years and older, the importance of safety in activities, such as sports, is becoming more important. It is vital to address the needs of this population through increasing education to prevent or address injuries related to physical activity. The overall purpose of this project was to determine the impact of providing sports safety education at the Holmen Area Community Center (HACC). Moreover, we sought to explore and educate the clients at HACC on ways to prevent such injuries and what to do if an injury does occur.

Many older …

The Shorthorn: January 8, 1952

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: April 24, 1951

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: February 27, 1951

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: November 21, 1950

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: December 5, 1950

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: October 17, 1950

The Shorthorn Newspaper Collection: 1950s

No abstract provided.

The Shorthorn: April 19, 1950

The Shorthorn Newspaper Collection: 1950s

No abstract provided.