Digital Commons Network^™

Beyond Opioids: The Role Of Polysubstance Exposure In Neonatal Abstinence Syndrome Treatment And Hospitalization, Caelyn Harrison

Undergraduate Honors Theses

This thesis explores the impact of prenatal polysubstance exposure, specifically focusing on the need for pharmacological treatment for Neonatal Abstinence Syndrome (NAS) and the duration of their hospital stay. A retrospective analysis of 462 infants, including 121 exposed to polysubstances during pregnancy, showed significant associations between polysubstance exposure and adverse neonatal outcomes. Infants with prenatal polysubstance exposure were more likely to require pharmacological treatment for NAS (52.8%) compared to non-exposed infants (38.7%), as determined by chi-square analysis (χ²(1, N = 462) = 7.36, p = .007). Additionally, infants exposed to polysubstances experienced longer hospital stays on average (M = 14.88 …

Lefitolimod In Combination With Ipilimumab In Patients With Advanced Solid Tumors: A Phase I Trial, Mirella Nardo, Mohamed A Gouda, Matthew J Reilley, Amadeo B Biter, Joann Lim, Stacie A Bean, Ly M Nguyen, Priya R Bhosale, Casey R Ager, Coline A Couillault, Sarina A Piha-Paul, Siqing Fu, Apostolia M Tsimberidou, Timothy A Yap, Aung Naing, Jordi Rodon, Vivek Subbiah, Daniel D Karp, Michael A Curran, David S Hong

Faculty, Staff and Student Publications

Introduction: TLR9 agonists are immunomodulators that have been of interest for combined use with cancer immunotherapy. TLR9 agonists, such as lefitolimod (MGN1703), significantly increased Th1 response in preclinical models and have demonstrated efficacy in early clinical trials. This trial assessed the safety and preliminary efficacy of the combination of lefitolimod and ipilimumab in patients with advanced solid tumors.

Methods: This was a single-center, open-label, investigator-initiated phase I trial conducted at The University of Texas MD Anderson Cancer Center. Patients received leftolimod either subcutaneously (at escalating doses of 15-120 mg) or intratumorally (at the maximum feasible dose) in combination with ipilimumab …

Assessing The Implicit Prices Of Health And Wellness Product Attributes In Pet Food: A Hedonic Analysis Approach, Lonnie Hobbs Jr., Andrew Anderson

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Here we examine product attributes present in dry dog food to show there exist potential price premiums and discounts associated with health and wellness attributes in dry dog food. The findings indicate price premiums are associated with attributes related to digestion and allergy care. Pricing discounts are found to be associated with immune support and dental attributes. The results of this study are anticipated to be a starting point for more sophisticated and dynamic analysis of pricing and willingness-to-pay studies in the pet food industry.

Evaluation Of The Implementation Of Foster Youth Independent Living Programs In The State Of California, Ingrid Flores

Electronic Theses, Projects, and Dissertations

Foster youth transitioning into adulthood often confront a myriad of challenges stemming from limited social capital and unstable support systems. The transition out of foster care, particularly for Transitional Age Youth (TAY), is fraught with barriers including disconnection from familial ties, inadequate knowledge regarding higher education, financial instability, unemployment, and housing insecurity. In 2021, approximately 4,920 foster children aged out of the system, facing the option to participate in extended care programs designed to facilitate their transition into independent living. Despite these programs, many youths struggle to achieve self-sufficiency. Key legislation, including the Child Abuse Prevention and Treatment Act, and …

Unintended Consequences: How Direct Cash Payments To Families Experiencing Poverty Lowered Child Poverty Rates In The United States, Wayne Dunn

Electronic Theses, Projects, and Dissertations

Child poverty has adverse effects for the children who experience it and it has long term social and economic consequences into adulthood. This policy analysis looks at the policy choices America has made in addressing child poverty and what effects, if any, those policies have had. After reviewing traditional in-kind policy options for addressing child poverty, this article focuses on the decreases in the child poverty rate that occurred with the passage of pandemic era legislation that provided direct cash assistance to all Americans. Because the assistance programs only happened in two consecutive years and were terminated at the end …

Social Media Use In Health Education: National Children's Dental Health Month Social Media Toolkit, Jazmin Pelayo

Electronic Theses, Projects, and Dissertations

National Children's Dental Health Month (NCDHM) was created by the American Dental Association and is celebrated annually by local oral health programs all around the country. The celebration began as a one-day event on February 8, 1949, expanded to a week-long observance in 1955, and was later extended to a month-long celebration in 1981. Today local oral health programs celebrate NCDHM in a variety of ways but the one I will be focusing on is a social media tool kit. A social media tool kit consists of videos or posts that are posted on different platforms such as the www.smilesbc.org …

Burnout Among Mental Health Professionals In Northern California: A Mixed-Methods Study, Sade Butler

Electronic Theses, Projects, and Dissertations

Burnout, characterized by prolonged emotional, physical, and mental exhaustion, is a widespread issue affecting millions of professionals in the United States and globally. Previous research has not adequately addressed the phenomenon of burnout, particularly in California. This study took a mixed-methods approach to determine the scope of, contributing factors to, and coping strategies for burnout among mental health professionals in Northern California. A sample of 93 mental health professionals completed a survey that contained both closed-ended and open-ended questions on burnout. Descriptive statistics indicated that 89.2% of participants experienced a moderate to severe level of burnout at work. Meanwhile, thematic …

Foster Care Alumni And Their Experiences Coping With Life After Care From The Perspective Of Pertinent Professionals, Nancy Morales

Electronic Theses, Projects, and Dissertations

ABSTRACT

Background: Children in foster care face significant challenges, and their transition to independent living presents even greater difficulties, such as securing housing, accessing healthcare, and achieving financial independence. Although recent policy reforms, such as increased emphasis on family reunification and support services, have aimed to improve the outcomes of foster care, alumni of the system continue to face disproportionately high rates of mental health disorders, substance abuse, and social instability. Existing literature highlights the significant barriers foster youth encounter during and after their time in care, yet there remains a critical gap in understanding the experiences of these individuals …

The Proverbial Milk And Honey: Frontier, Racial Lines, And The Development Of California Foodways, Ahlys Gandara

Electronic Theses, Projects, and Dissertations

This thesis proposes that the development of foodways in the state of California occurred concurrently with the development and failures of Americanization and the American frontier. This is done with respect to the fact that California has a much longer history than that of the United States. While foodways are often discussed and examined within the ideas of nationalization, this becomes harder to do within the United States as there is no unifying idea of a national identity and any attempts to do so were hampered by the lack of consensus as to a singular identity. This is especially true …

Barriers Individuals And Families Experience Utilizing Anti-Poverty Programs, Miranda C. Dube'

Electronic Theses, Projects, and Dissertations

This proposed study aims to explore the barriers experienced by residents of the High Desert communities. Using a quantitative method approach, the proposed research will employ surveys to provide a comprehensive understanding of the outcomes experienced by the High Desert residents. Participants will be selected within the High Desert communities, aged 18 years or older, who have or are currently experiencing poverty. The findings from this proposed study would contribute to bridging gaps in understanding the barriers residents of the High Desert experience. By identifying factors that suppress successfully utilizing anti-poverty programs, this research proposal would aim to inform the …

Engineering An In Vitro Hipsc-Derived Cardiac Tissue Construct For Regenerative Medicine Applications, Larry Mendoza

Electronic Theses, Projects, and Dissertations

Cardiovascular disease is the leading cause of mortality across the world with invasive surgeries and pharmaceutical intervention commonly associated with urgent care. Moreover, congenital, progressive, and hereditary heart diseases rely on many forms of medical prevention and intervention (pharmaceuticals, x-rays, bloodwork, etc.). Developing a three-dimensional (3D) cardiac tissue engineered in vitro model to study human cardiac physiology can revolutionize biomedical research. The purpose of this research is to optimize natural & synthetic biomaterials to fuse cardiac stem cells and synthesize a 3D-printed in vitro model for disease modeling, drug delivery, and regenerative medicine. Natural biopolymers needed for such innovations are …

Exploring The Factors That Influence Telehealth Usage Among Immigrants In The United States: A Mixed Methods Study, Jose M. Garcia-Castañeda

Electronic Theses, Projects, and Dissertations

Background: Immigrants in the United States continue to face barriers in accessing healthcare services which are rooted in systemic inequities, cultural disconnects, and language-related challenges. The growing presence of telehealth services has offered new opportunities to expand access, but it has also highlighted new barriers which are language proficiency and digital literacy which could increase the gap in services for already marginalized populations. These barriers are factors that influence outcomes such as delayed care, reduced preventative care, and overall poorer health outcomes. The Andersen Behavioral Model of Health Service Use (Andersen, 1995) provides a useful framework in understanding how predisposing, …

Case Management Is Essential In A School-Based Setting, Estrella G. Moreno

Electronic Theses, Projects, and Dissertations

ABSTRACT

Case management in a school-based setting is an integral part in helping students overcome barriers by providing support services. These support services include meeting their physiological needs like food, shelter, and clothing. When students lack necessities, it prevents them from focusing on their academics. Therefore, developing feasible plans to address students’ needs is vital to a student’s continued academic success. The research question is as follows: What percentage of students who are referred to case management services end up having their needs successfully met? This study examined the number of students among the K-12 student population in Colton Joint …

Development Of A Jamaican-Inspired Cookbook And Nutrition Resources For Prevention And Management Of Diabetes, Stacy Ann J. Cameron-Roberts

Electronic Theses, Projects, and Dissertations

Background & Aims: Diabetes disproportionately affects minority populations, including Jamaicans affected by dietary habits, sedentary lifestyles, and socioeconomic factors. Culturally relevant interventions are essential for promoting sustainable health behaviors to prevent diabetes. This project developed a Jamaican-inspired cookbook with nutrition education to improve dietary habits among Jamaicans to avoid diabetes.

Methods: The project titled Authentic Flavors: Healthy Jamaican Dishes for People with Pre-Diabetes, a cookbook and resources featuring 34 modified Jamaican recipes with nutrient-dense, low-glycemic ingredients to prevent rapid spikes in blood glucose. Participants were recruited from Jamaican community; and they completed an online nutrition education with pre- and …

The Impact Of Social Media On Dietary Choices Among Young Adults, Celeste Martin

Electronic Theses, Projects, and Dissertations

Background and aims: For decades, the field of nutrition has been influenced by advertising, fad diets, and celebrity endorsements, often leading to confusion. Social media has introduced a new level of influence, potentially leading to more misinformation about health and nutrition. Platforms like TikTok, Instagram, and Facebook may serve as a primary source of news and information for young adults, drastically changing how nutrition advice is shared. Research suggests that social media can positively and negatively impact people’s views on health and nutrition, such as a poor relationship with food and a negative body image. This study aimed to …

Impact Of Water Quality On The Nutritional And Phytochemical Properties Of Culinary Herbs, Genesis Arroyo

Electronic Theses, Projects, and Dissertations

Water quality significantly affected food safety, especially since contaminated water impacted crop growth and the nutrient composition of foods. Nitrates occur naturally in vegetables. However, when introduced into the food supply through water contamination, excessive levels disrupted the natural physiological processes of vegetables and other agricultural plants. These excessive levels eventually led to nutrient imbalances, decreased phytochemical concentrations, and potential health risks such as the formation of carcinogenic N-nitroso compounds in humans. This study evaluated the effects of nitrates on the nutritional outcomes of food crops, focusing on commonly used culinary herbs. While synthesizing findings from relevant peer-reviewed articles, I …

Drinking Out Of The Fire Hydrant: Educators’ Perceptions Of Well-Being In A Teacher Preparation Program, Corey P. Wolfe

Electronic Theses and Dissertations

The process of becoming a teacher is complex, multi-layered, and often high-stakes. Teacher preparation programs are designed to equip prospective teachers with the foundational skills and knowledge needed for a successful teaching career. In addition to pursuing the academic degree in education, future teachers must meet credentialing and licensure expectations. Because of these expectations, novice teachers are often met with profound feelings of stress and anxiety. The purpose of this research exploration was designed to investigate elementary educators’ perceptions of well-being during their senior year in a pre-service teacher preparation program. Using a qualitative research design, six educators were interviewed …

Investigation Into Mycorrhizae Associated With Native Venus' Flytrap Root Tissue, Anna Carnaggio

Electronic Theses and Dissertations

Dionaea muscipula, a plant commonly known as the Venus' flytrap, is found native to the southeast corner of North Carolina and the northeast corner of South Carolina. Several populations of native Venus' flytraps are known to exist in the nutrient-poor peat bog conditions in and around Lewis Ocean Bay Heritage Preserve (LOBHP) in Northeastern South Carolina. Anthropogenic pressures in Horry County, specifically surrounding LOBHP, have resulted in a loss of habitat for several native and endangered species. As a result, conservation efforts are focused on relocating native Venus' flytraps into adjacent habitats to ensure survival. This is only a temporary …

A Randomized Clinical Trial Exploring Two Doses Of Cannabidiol Daily For Eight Weeks On Health And Stress, Ryland Emery Townsend

Dissertations

This study’s purpose was to explore whether a 60 or 30 mg dose of cannabidiol (CBD) consumed in a beverage further supplemented with L-theanine, vitamin E, and vitamin C would alter various measures on subjective measures of stress, health and fitness related outcomes, and objective measures of stress. This double-blind, placebo-controlled clinical trial recruited healthy, college-aged subjects for randomization into one of four treatment groups where they consumed daily a single 12 ounce beverage for eight weeks containing 1) 60 mg CBD (CBD60) plus L-theanine; 2) 30 mg CBD (CBD30) plus L-theanine; 3) no CBD (CBD0), L-theanine alone, and 4) …

Effectiveness Of Maternal Bovine Appeasing Substance Administered To Newly Received, High-Risk Stocker Calves, Elle Johnston

Animal Science Undergraduate Honors Theses

Stocker cattle purchased at auction can be susceptible to disease due to the stressors associated with the auction process. These cattle are labeled “high-risk” due to their compromised immune system during transportation, handling, and vaccination processes. The objective of this study was to determine the efficacy of a maternal bovine appeasing substance, FerAppease, on growth performance and behavior of stocker cattle. Male beef calves (n=80) were purchased at auction and transported to the University of Arkansas Division of Agriculture Savoy Research Complex Beef Stocker Unit. Steers and bulls were of varying age, breed, and temperament. Upon arrival to the facility …

Rhetorics Of Vigilance: Refracting Discourses In Technologies Of Self-Managed Health & Wellness, Haley Swartz

All Dissertations

Rhetorics of Vigilance explores the limits of feminist health rhetorics by examining technologies that promote women’s self-managed health and wellness practices. By establishing a corpus of personal health technologies and associated texts including mobile health applications, pelvic floor training devices, and perimenopause information shared on social media, this dissertation analyzes how discourses refract––redirected and often distorted––to implicate women in persistent self-monitoring. Drawing from interdisciplinary scholarship on women’s health from feminist rhetorical studies, rhetorics of health and medicine, science and technology studies, and digital studies, I theorize rhetorics of vigilance as a framework through which women understand and interpret issues …

The Effect Of Storyline Units On The Self-Efficacy And Science Identity Of High School Multilingual Learners, Kristin Ambrose

All Dissertations

Science can be a complex subject for multilingual learners (MLLs) because it requires investigating science concepts through modeling and analysis in addition to reading and writing skills. This complexity often leaves teachers unsure of how to support the MLLs, leading to MLLs missing out on grade-appropriate content and science experiences. Storyline instruction uses 3D instruction to teach science content necessary to explain a real-world anchoring phenomenon. Storyline instruction grounds learning in real-world contexts through anchoring phenomena and provides coherence for students throughout the lessons. This mixed methods study aimed to discover the impact of storyline units on the self-efficacy (SE) …

The Quest For Kindergarten Readiness: A Study Of One District’S Early Implementation Of The Pyramid Model For Promoting Social-Emotional Competence, Ginny L. Gast

All Dissertations

Participation in high-quality preschool programs can help prepare young children for Kindergarten, and children demonstrating Kindergarten readiness are more likely to achieve positive outcomes later in life. With this in mind, Oakwood School District (OSD) set a strategic goal to improve the Kindergarten readiness levels of students participating in its 4K programs from 18% in 2021 to 70% by 2025. With research suggesting that school readiness outcomes are dependent on preschool program quality variables such as student-teacher relationships and emotional competencies, the Pyramid Model for Promoting Social-Emotional Competence in Infants and Young Children was implemented in OSD’s 4K program sites …

The Administrators’ Role In Teacher Retention And Their Role On Teachers’ Perceptions Of School Climate At An Exemplar Title I School: A Qualitative Study, Stephen W. Brown Iii

All Dissertations

This study looks at how principals affect teacher perception of school climate and teacher retention at Title I schools. While teacher retention and school climate have historically been issues at Title I schools, the issue has been exacerbated by the COVID-19 pandemic. This qualitative study explored an elementary school in South Carolina through the lens of Critical Systems Theory. According to publicly available data, this school was an anomaly among Title I schools regarding the climate and teacher retention, with both measures being extremely high. To explore these phenomena, semi-structured interviews were conducted with both the teachers and administrators at …

Investigate The Use Of Nucleic Acids As Pesticides To Manage Major Pests And Pathogens Of Crops In South Carolina, Prasanna Valavanur Shekar

All Dissertations

The sugarcane aphid (SCA, Melanaphis sorghi), first discovered on grain sorghum in late 2013, has gradually become a major insect pest of sorghum. It inflicts significant damage to the crop year after year, causing millions of dollars in losses throughout the sorghum-producing regions of the United States. Similarly, Armillaria root rot—also referred to as oak root rot—is a major cause of decline in peach (Prunus persica) production in the southeastern United States. This disease is caused by Armillaria mellea and Armillaria tabescens. Current management practices for controlling M. sorghi include the use of synthetic pesticides, resistant varieties, and regular scouting. …

The Role Of Responsive Feeding In Childhood Development And Clinical Implications: A Comprehensive Literature Review, Alexander Burbach

Capstone Experience: Master of Public Health

Responsive feeding refers to caregiver-infant feeding interactions that encourage healthy eating behaviors and support the child’s autonomy by responding to their hunger and satiety cues. Responsive feeding supports healthy early childhood development, influencing self-regulation in eating behaviors and long-term health outcomes, particularly in obesity prevention. A comprehensive literature review was conducted to examine the impact of responsive feeding practices on childhood development in the United States and its clinical implications. The objectives were to explore the role of parental feeding practices in shaping childhood eating behaviors, understand the relationship between responsive feeding and obesity, and determine literature daps. Articles for …

Optimizing Case Management Manuals: A Ryan White Quality Improvement Project For Northwest Missouri, Megan Mcbane

Capstone Experience: Master of Public Health

The Ryan White HIV/AIDS Act, established in 1990, has played a critical role in providing essential services for individuals living with HIV, including medication access, adherence support, health coverage, housing, and transportation. In rural Missouri, particularly in the northwest region, HIV case management under the Ryan White program is guided by four separate manuals, creating inefficiencies and burdens for case managers. This paper presents a process evaluation plan utilizing the Plan-Do-Study-Act (PDSA) framework to address these challenges and improve service delivery. The aim of this quality improvement project is to enhance the efficiency and effectiveness of HIV case management in …

A Research Report: What Are The Challenges That Refugee Women Experience When Seeking Healthcare Related To Pregnancy In The United States?, Manuela Krieger-Adi

Capstone Experience: Master of Public Health

Background

Refugees in the United States, including African refugee women, face many challenges in seeking healthcare after moving to the United States to resettle. It is urgent and essential to look into some of the health challenges the refugee community faces here in Omaha, Nebraska, that prevent them from seeking healthcare, especially when pregnant. This Capstone research project aims to focus on African refugee women, specifically in Omaha, Nebraska, and the challenges they face seeking healthcare related to pregnancy.

Methods

This research report involved five in-depth interviews conducted over Zoom. The target population was refugee mothers who had given …

Assessing The Association Between Total Cholesterol And Hospitalized Myocardial Infarction In Women Ages 32-70: An Analysis Of The Framingham Heart Study, Jolene L. Stapleton Duree

Capstone Experience: Master of Public Health

Objective

Heart disease is the leading cause of death in women that may go undiagnosed due to unexpected symptoms. The purpose of this analysis was to assess the effect of total cholesterol on the odds of hospitalized myocardial infarction (MI).

Methods

This analysis used a sample of 2,445 women from the Framingham Heart Study, an observational prospective cohort study. The exposure was total cholesterol, and the outcome was hospitalized MI. Logistic regression was used to estimate crude and adjusted odds ratios (OR). The adjusted models controlled for age, blood pressure, and diabetes. Effect modification by diabetes status was evaluated in …

The Wellness Connection May 2025, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.