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High-Frequency, At-Home Monitoring Of Drug Safety And Tolerability In Clinical Trials: Results From Studies Of Fluvoxamine For Covid-19 Treatment, Eric J Lenze, Madeline Nykamp, J Philip Miller, Angela Stevens, Julia Schweiger, Torie Gettinger, Michael Yingling, Yi Zhang, Ginger E Nicol, Charles F Zorumski, Angela M Reiersen

2020-Current year OA Pubs

Clinical trials are increasingly using remote monitoring techniques at the patient's home. We conducted a secondary analysis of remote safety and tolerability monitoring from two fully-remote clinical trials that tested fluvoxamine for the acute treatment of COVID-19. Both trials assessed pulse and blood pressure daily, and one study assessed symptoms daily via Ecological Momentary Assessment. On average, patients provided data on vital signs on 93% of the study days and provided data on side effects on 81% of the study days. With respect to safety, patients taking fluvoxamine had reduced pulse rate compared to placebo, with the greatest difference-5 points-at …

The Artichoke Model: A Conceptual Framework For Positive Food Environments In Early Childhood Education And Care (Ecec) Settings, Ros Sambell, Audrey Elford, Tori Overstone, Rebecca Byrne, Kirsty Elliott, Sandra Vale, Penelope Love, Lisa Vincze, Leanne Elliston, Fiona Nave, Janny Goris, Emma Esdaile, Amanda Devine

Research outputs 2022 to 2026

The Artichoke Model is a conceptual framework developed to support the understanding of the breadth and influence of food environments in Early Childhood Education and Care (ECEC) settings. It identifies twelve interrelated components spanning food provision, mealtime practices, curriculum integration, staff capacity, family engagement, and systemic enablers such as policy, equity, and environmental sustainability. Represented visually as an artichoke with the child at its centre, the model encourages holistic analysis, recognising that sustainable change requires the interconnected operation of all components, rather than isolated interventions. The Artichoke Model is intended as a tool for researchers, policymakers, and advocates to guide …

Breast And Prostate Cancer Survivors’ Understanding Of Risk And Management Of Cardiovascular And Musculoskeletal Side Effects Of Treatment: Findings From Focus Groups, Jack Dalla Via, Chris R. Andrew, Brenton J. Baguley, Nina Stewart, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley, Mary A. Kennedy

Research outputs 2022 to 2026

Purpose: Survival after a cancer diagnosis is improving, increasing the importance of understanding and managing long-term treatment-related adverse effects. This study aimed to understand breast and prostate cancer survivors’ understanding of how cancer treatment may affect cardiovascular and musculoskeletal health. Methods: Australian breast and prostate cancer survivors treated with therapies with known cardiovascular adverse effects were recruited via a private cancer care provider. Participants completed an online background questionnaire, then participated in a focus group. Focus groups were recorded, transcribed, then analysed using reflexive thematic analysis. Results: In total, 26 cancer survivors (15 breast, 11 prostate; mean age 67 years) …

Blue Light Is A Key Factor In Regulating Stomatal Movement, Transpiration Rate And Aba Metabolism Under Varying Vapour Pressure, Sheona Noemi Innes, Sara Brunborg Jakobsen, Rikke Bryn Røsåsen, Haider Ali, Knut Asbjørn Solhaug, Jorunn Elisabeth Olsen, Sissel Torre

Research outputs 2022 to 2026

Vapour pressure deficit (VPD) and blue light (BL) are import signals for stomatal regulation and highly relevant during cultivation of economically important crops such as cucumber in controlled environments. However, the information about combined effects of VPD and BL and the regulation of abscisic acid (ABA) in this respect, is limited and seems to vary between species. This study investigated how moderate (1.12 kPa) or low (0.28 kPa) VPD combined with 5% or 30% BL affect the foliar ABA metabolism, transpiration rate, nutrient uptake, and growth in well-watered cucumber plants (Cucumis sativus ‘Quatro’). Additional BL, regardless of VPD, resulted in …

Evaluating The Influence Of Carbon Quantum Dots On Starch-Based Bioplastics: Toward Potential Food Packaging Applications, Shima Jafarzadeh, Mitra Golgoli, Zeinab Qazanfarzadeh, Mehrdad Forough, Peng Wu, Wendy Timms, Colin J. Barrow, Minoo Naebe, Masoumeh Zargar

Research outputs 2022 to 2026

Developing biodegradable food packaging films is crucial for reducing dependence on petroleum-based plastics. In this study, nitrogen-doped carbon quantum dots (CDs) were synthesized from citric acid and ethylenediamine via hydrothermal treatment and incorporated into sago starch films at concentrations of 0.5 %, 1 %, 3 %, and 4 % w/w of total solids using a solution casting method. The effects of CDs on structural, thermal, antioxidant, optical, and physicochemical properties were systematically investigated. CD addition enhanced the UV-shielding ability of the films. At 4 % CD content, UV transmittance decreased by 56.4 % (UVA), 66.7 % (UVB), and 73.9 % …

Foundations And Strategic Vision Of The Canadian Translational Geroscience Network, Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, Gustavo Duque

Research outputs 2022 to 2026

Geroscience is an emerging interdisciplinary field that explores the biological connections between aging and the development of chronic diseases, with the ultimate goal of identifying interventions to extend healthspan and delay age-related conditions. Recognizing the growing importance of this field, the Canadian Translational Geroscience Network (geroscience.ca) was officially launched during a conference held in Montreal on September 5-6, 2024. Building on the momentum of successful Geroscience meetings in Toronto and Montreal in 2023, this milestone event marked a transformative step forward for geroscience in Canada. This event brought together key stakeholders, including the Canadian Frailty Network (CFN), the Canadian Institutes …

Time Alters Distinct Memories Driven By Sensory Prediction Errors And Task Errors In Sensorimotor Adaptation, Li Ann Leow, Welber Marinovic, Scott Albert, Timothy J. Carroll

Research outputs 2022 to 2026

Prior learning can impair future learning when the requirements of the two memories conflict, a phenomenon termed anterograde interference. In sensorimotor adaptation, the passage of time between initial and future learning can reduce such interference effects, leading to the interpretation that time consolidates motor memories, protecting motor memories from interference. However, we still do not fully understand how time affects learning, as some studies found no effects of time on interference. One possible explanation for such inconclusive findings is that time has distinct effects on the multiple processes underpinning sensorimotor adaptation, and these processes may compensate for each other's effects …

Transforming K-12 Classrooms: Ten Essential Strategies For Cultural Responsiveness, Sandra Johnson, Stephanie Johnson, Regina Reber

Journal of English Learner Education

Across the United States, in K-12 classrooms, diverse student populations continue to increase, challenging educators to meet student cultural, linguistic, and academic needs. The study examined the best practices related to culturally responsive teaching (CRT) strategies to better meet all students' needs. A qualitative approach was used to collect data from licensed K-12 educators in New Mexico and Colorado. The findings revealed three essential themes: culturally responsive pedagogy, the positive impact of CRT, and the creation of physical spaces to support inclusivity. The findings revealed the significance of building strong relational capacity, encouraging collaboration, supporting multilingualism, and creating effective physical …

Pushing Consumers To Plant-Based Milk Alternatives: What Drives Them?, Rabani Jannata Insani, Fatya Alty Amalia

ASEAN Marketing Journal

Manuscript type: Research Article

Research Aims: Describing the extent to which belief factors, supporting reasons, and opposing reasons can shape attitudes, thereby creating an intention to purchase plant-based milk products.

Design/methodology/approach: Using Behavioral Reasoning Theory. Data were collected through quantitative methods from 407 respondents using a questionnaire, targeting those who had consumed plant-based milk. Analyzed using the Partial Least Squares Structural Equation Modeling (PLS-SEM) method using SmartPLS 3.0.

Research Findings: The findings indicate that health beliefs, reasons for nutritional content, and supporting the environment significantly influence attitudes positively, while environmental beliefs have a positive but non-significant impact on attitudes. However, …

Nutritional Quality Of Subterranean Clover Cultivars In West Central Spain, B Garcia-Criado, A Garcia-Ciudad, M Rico-Rodriguez, L Garcia-Criado

IGC Proceedings (1977-2023)

The nutritional quality of 61 subterranean clover (Trifolium subterraneum L.) cultivars was studied, during 1982, in the province of Salamanca (semiarid zone of west central Spain). Plant samples were collected at the late-bloom stage and were analyzed for protein, carbohydrates and digestibility. The levels of all these constituents fluctuated within acceptable ranges. Higher relative variability was observed in respect of hemicellulose, protein and lignin, while the digestibility values presented lower relative variability. The latter ranged from 71.1 to 76.1 % with a mean of 73.3%, while protein values ranged from 11.1 to 19.4% with a mean of 14.0%. Chemical …

Effects Of Frequency And Height Of Defoliation On Forage Yield And Crude Protein Content Of Flemingia Macrophylla (Flemingia), E O. Asare

IGC Proceedings (1977-2023)

Defoliation studies were conducted over a period of 3 years on the same stands to determine the effects of 3 heights 5, 20 and 35cm and 3 intervals, 8, 12 and 14 weeks of cutting on leaf dry matter (DM) yield and nutritive value of Flemingia macrophylla (Flemingia) a potential fodder shrub. Both height and interval of cutting had significant effect on leaf DM yield. There was significant interaction between frequency and height of cutting. Leaf DM yield decreased with lowering of cutting height and increased through increasing interval between cuts. The 14-week cutting interval and 35cm cutting height treatment …

A Study Of Phenology, Herbage Yield And Crude Protein Content Of Native Ecotypes Of Red Bromegrasses (Bromus Tomentellus Boiss.) Of Iran, B Peymani-Fard

IGC Proceedings (1977-2023)

This research was conducted on ten ecotypes of red bromegrasses of Iran at Homand Range Experiment Station, near Damavand, Iran to asses: (a) the differences in phenological characteristics, (b) to evaluate differences in herbage yield, and (c) determine the crude protein percentage Parameters measured include duration of vegetative, heading, maturity stages, herbage yields, and crude protein. Variation in vegetative growth, heading and seed maturity stages among the ecotypes under study was very small

Therefore, there are no prefences in selection of a specific ecotype from the standpoint of utilization and harvesting time. There was a great fluctuation in annual herbage …

Facilitating Living Kidney Donation: Retrospective Evaluation Of Weight Loss Interventions To Support Kidney Donation, Julia Dumitrescu

Graduate Medical Education Research Journal

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Characteristics Of Anxiety And Stress-Triggered Inducible Laryngeal Obstruction, Jacob Middleton

Graduate Medical Education Research Journal

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Multisystem Inflammatory Syndrome In Adults (Mis-A) Leading To Shock In A Previously Healthy Male, Zachary Brodie

Graduate Medical Education Research Journal

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Appropriate Dvt Prophylaxis Usage Among Patients Admitted To Meyer Academic Teams, Zachary Brodie

Graduate Medical Education Research Journal

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Temporomandibular Joint Articular Eminence Anatomy As A Predictor Of Anterior Disc Displacement On Mri, Serin Lee

Graduate Medical Education Research Journal

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A Rare Case: Dental Panoramic Radiograph Leads To The Diagnosis Of A Large Internal Carotid Artery Aneurysm, Vivek Sharma

Graduate Medical Education Research Journal

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Inpatient Genetics Service And Testing Trends: A Retrospective Multi-Institution Analysis (2021-2024), Travis Schreier

Graduate Medical Education Research Journal

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Extracorporeal Membrane Oxygenation (Ecmo) And Abdominal Complications In Adults: Identifying The Risk Factors, Tyler Austin

Graduate Medical Education Research Journal

NA

Assessing The Impact Of A Resident Wellness Curriculum: A Retrospective Study In An Internal Medicine Residency Program, Ram Prakash Thirugnanasambandam

Graduate Medical Education Research Journal

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The Effect Of Pitch Clock Rules On Pitching Injuries In Milb From 2012 To 2024, Scott Goodsell

Graduate Medical Education Research Journal

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The Hamate: An Unexpected Fracture, Jackson Bagby

Graduate Medical Education Research Journal

NA

Temporal Trends Of Obesity Among Nebraska Adults: Emr Data Shows A More Rapid Increase Than Projected, Elizabeth Gibson

Graduate Medical Education Research Journal

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An Atypical Cause Of Headache In An Athlete, Brittany Weaver

Graduate Medical Education Research Journal

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Cold Truths Exposed: An Uncommon Culprit Of Neonatal Hypothermia, Stephanie Radil

Graduate Medical Education Research Journal

NA

Policy Analysis On Million Hearts 2027, Cardiovascular Health, Priyanka Gera

Quill & Scope

No abstract provided.

The Current Status Of Multi-Modality Imaging Of Pulmonary Emboli, Rodney C. Fisher, Kimberly L. Onstott

Internet Journal of Allied Health Sciences and Practice

Background: Pulmonary emboli (PE) have a significant incident rate of 112.3 per 100,000 adults. When age-weighted, the population over 75 has an incident rate of 1 out of 100. 90% of deaths from acute cases occur within two hours of the onset of symptoms. In pregnancy-related deaths, 20% are attributed to PE, and pregnancy increases the risk of the development of PE by 400 – 600%. Significant risk factors for PE include COPD, obesity, recent trauma or surgery, a history of deep vein thrombosis (DVT), a history of hormonal therapy, smoking, and pregnancy. Purpose: This literature review discusses how PE …

Clinical Outcomes After Hospitalization For Acute Coronary Syndrome In Patients Treated With Semaglutide Versus Bariatric Surgery: A Retrospective Multicenter Analysis, Nameer Ascandar, Charles Boadu, Gauthier Stepman, George Skaf, Olugbenga Oyesanmi, Sabry Omar, Rias Ali, Michael Schandorf-Lartey

HCA Healthcare Journal of Medicine

Background

Obesity is a chronic medical condition with a rising prevalence in the United States. A wide range of morbidity and mortality is associated with obesity, with coronary artery disease being among the most common. Ischemic heart disease continues to be the primary cause of death in the United States. Taken together, interventions to minimize the detrimental effects of obesity on patients at risk of heart disease will not only benefit the patient, but the health care system as well.

Methods

In this retrospective study, we used the HCA Healthcare enterprise data warehouse to identify all adult patients who were …

The Relationship Between Fast Food Consumption And Physical Activity With Primary Dysmenorrhea In Adolescents, Wahyuni Wahyuni

Jurnal Vokasi Indonesia

Background: Menstruation is a bleeding event that occurs when the inner lining of the uterus, known as the endometrium, sheds. Dysmenorrhea is one of the symptoms that teenage girls often feel during menstruation. Dysmenorrhea can affect women's comfort and quality of life. There are two types of dysmenorrhoea, namely primary dysmenorrhea and secondary dysmenorrhoea. Primary dysmenorrhoea refers to the condition of menstrual pain that adolescent girls often experience, with a prevalence rate of 60-90%. Risk factors for primary dysmenorrhoea are influenced by several factors, including fast food intake, physical activity level, stress level, age at first menstruation (menarche), and nutritional …