Digital Commons Network^™

Prevalence And Risk Factors Of Concurrent Osteoarthritis And Urolithiasis In Dogs In Thailand (2018–2020), Faiz Ihsanul Kamil, Kumpanart Soontornvipart

The Thai Journal of Veterinary Medicine

Osteoarthritis is a degenerative joint disease that significantly impacts dog health, often leading to chronic pain, reduced mobility, and behavioral changes that may predispose dogs to secondary conditions such as urolithiasis. This study aimed to investigate the association between osteoarthritis and urolithiasis in dogs using radiographic imaging data collected from the Small Animal Teaching Hospital, Chulalongkorn University, Thailand, over a three-year period (January 2018 to December 2020). A total of 16,377 dogs were included, and cases of osteoarthritis, urolithiasis, or the concurrent occurrence of both conditions were identified through a systematic database review. Binary logistic regression models were used to …

Drought And Herbivory Have Selective Transgenerational Effects On Soybean Eco-Physiology, Defence And Fitness, Manish Gautam, Rupesh Kariyat

Entomology and Plant Pathology Faculty Publications and Presentations

Soybeans, one of the most important legumes, face multiple stresses including drought and herbivory. But the potential transfer of the interactive effects of these stressors onto the transgenerational plants has not been understood. We hypothesised that progeny from stressed parents will have enhanced ecophysiology and defence traits through priming, affecting fitness. Experimental plants were derived from seeds of drought (D), drought and herbivory interaction (D & times; H), herbivory (H) and well-watered (WW) treatments imposed on parental generation. The findings revealed significant transgenerational effects of D, D & times; H, H and WW treatments; D & times; H treatment had …

Assessing Natural Resources Conservation Service (Nrcs) Impacts On Rice And Soybean Efficiency In The Mid-South, Ayodeji Samuel Ayiti

LSU Master's Theses

The study investigates how the Mid-South region of the U.S. rice and irrigated soybean production efficiency is influenced by (NRCS) incentives. To evaluate the effect of crop insurance, subsidies, and conservation incentives on lowering inefficiency, this study used a stochastic frontier model (SFA). The dataset covered the years 2010 – 2023, which allowed for a thorough evaluation of efficiency trends over time. While crop insurance programs reduce inefficiency in rice production, it shockingly increases inefficiency in soybean production, according to the study, which highlights the disparate effects of net support (insurance-subsidy).

The results show that while external factors like changes …

Firefighters Versus Law Enforcement Officers: A Comparison Of Cardiovascular Disease Risk, Bethany C. Guerra, Steven E. Martin, Lisa C. Colvin, J. Jay Dawes, Matthew J. Mcallister, Drew E. Gonzalez

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 659-671, 2025. Firefighters (FFs) and law enforcement officers (LEOs) have heightened cardiovascular disease (CVD), with data suggesting that ≈45% of on-duty FF fatalities are related to CVD, while LEOs have a 1.7 times higher CVD prevalence than the general public. This study compared CVD risk biomarkers, fitness, and body composition between FFs and LEOs. Ninety-eight career, structural male FFs (age = 35.1±9.6 yrs; weight = 94.3±15.4 kg; height = 178.4±13.2 cm) and seventy-three career LEOs (age = 41.4±9.0 yrs; weight = 92.3±16.8 kg; height = 179.6±8.1 cm) from local departments were studied. Participants completed …

Neurophysiology And Endocrine Responses To Hunger And Satiety Mechanisms: The Brain-Gut Crosstalk, Nour Shakir Rezaieg, Muthanna M. Awad

Karbala International Journal of Modern Science

Background: Obesity is a main public health problem which substantially increases the risk of many diseases. The complex neural circuitry controls energy homeostasis and food consumption by the incorporation of hormonal and neural signals. Circulating hormones, in specific the gut hormones, have been found to be very important in appetite regulation. These hormones transfer energy situation signs to the brain throughout three principle paths: the circulation system, activation of the vagus nerve, and direct modification of main brain regions such as the hypothalamus and brainstem. The control of food eating is not exclusively dependent on the homeostatic processes, rather it …

Digitally Fabricated Interocclusal Wafer Versus Wafer-Less Distal Segment Repositioning For Bilateral Sagittal Split Osteotomy (Bsso) In Skeletal Mandibular Deformities (Randomized Controlled Trial), Hesham Osama Morsi Ass.Lect., Mohammed Abdelsalam Omara Ass.Prof., Mostafa Ibrahim Shindy Prof, Galal Gamal El Behairy Prof.

Dentistry

Objective: This study aimed to compare the accuracy of condylar positioning between 2 computer-guided orthognathic surgical protocols: a waferless screw hole plate locating (WSL CPD) technique versus an occlusal splint with distal extending arms (OWDA-CPD) approach. Materials and Methods: Twenty-four patients requiring mandibular orthognathic surgery (class II or III deformities) were randomly allocated into 2 groups (n=12 each). Group I underwent a waferless protocol utilizing 3D-printed osteotomy and screw hole locating guides, while group II received an occlusal splint with distal extensions for condylar positioning. Preoperative and postoperative cone-beam computed tomography (CBCT) scans were used to assess condylar displacement in …

Technology And The Sustainable Implementation Of The African Continental Free Trade Area (Afcfta) Through Women’S Integration, Philip Ademola Olayoku

Journal of African Policy Studies

The desire for economic prosperity on the African continent led to the African Continental Free Trade Area (AfCFTA), in line with the vision of the Organisation of African Unity (OAU), when it proposed the creation of an African Economic Community (AEC) by 2028. However, sustainable economic development will remain a mirage without inclusivity where no one is left behind, in line with the African Union’s Agenda 2063. This study explores the challenge of restricting women to economic margins in trade agreements under the AfCFTA and how this would undermine its implementation. It subsequently contends that women are integral to Africa’s …

Slc2a1 And Its Related Epileptic Phenotypes, Francesca Patanè, Elisa Pasquetti, Federica Sullo, Monica Tosto, Catia Romano, Stefania Salafia, Raffaele Falsaperla

Journal of Pediatric Neurology

Glucose transporter type 1 deficiency syndrome (GLUT1DS) is caused by heterozygous, mostly de novo, mutations in SLC2A1 gene encoding the glucose transporter GLUT1, the most relevant energy transporter of the brain through the blood-brain barrier. GLUT1DS includes a broad spectrum of neurologic disturbances, from severe encephalopathy with developmental delay, epilepsy, movement disorders and acquired microcephaly to atypical mild forms. For diagnosis, lumbar puncture and genetic analysis are necessary and complementary; an immediate response to ketogenic diet supports diagnosis in case of high suspicion of disease and negative exams. The ketogenic diet (KD) is the first line treatment and should be …

Aldh7a1 Gene And Its Related Pyridoxine-Dependent Epilepsy, Flavia M.C. La Mendola, Tiziana Timpanaro, Daniela Caruso, Maria Teresa Garozzo, Santiago Presti, Catia Romano, Elena R. Praticò, Antonio Zanghì, Raffaele Falsaperla

Journal of Pediatric Neurology

Despite being classically reported as caused by mutations in solute carriers genes (SLC2A1), it has been recently shown that also mutations in ALDH7A1 can cause pyridoxine-dependent epilepsy (PDE). ALDH7A1 is a gene encoding for the antiquitin, an enzyme that catalyzes the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-α-aminoadipic semialdehyde/L-Δ1-piperideine 6-carboxylate. It is a highly treatable disorder, but nevertheless it is still not certain when to consider this diagnosis and how to test for it. It is possible to identify a classical form and an atypical one of PDE associated with more than 70 mutations of ALDH7A1 gene. The typical form is …

Effect Of Polygonatum Sibiricum Powder On Properties Of Dough And Quality Of Bread, Wu Kunwei, Wei Ming, Qian Senhe, Li Ziman, Xie Yan

Food and Machinery

［Objective］ To explore the application of Polygonatum sibiricum powder in bread,enhancing its health benefits.［Methods］ Polygonatum powder is added to wheat flour to study its effects on starch gelatinization,gluten structure,dough rheological properties,and bread baking quality.［Results］］ The addition of Polygonatum powder increases the gelatinization temperature of the flour,while peak viscosity and retrogradation values decrease.The gluten yield in the dough is reduced.Changes in the secondary structure of gluten proteins are observed,with an increase in the content of random coil structures.Polygonatum sibiricum powder increases dough hardness,elasticity modulus,and viscosity modulus,but it reduces the dough's fermentation volume.The baking quality of the bread is affected,with the bread …

The Current And Future Burden Of Long Covid In The United States, Sarah M Bartsch, Kevin L Chin, Ulrich Strych, Danielle C John, Tej D Shah, Maria Elena Bottazzi, Kelly J O'Shea, Mckaylee Robertson, Colleen Weatherwax, Jessie Heneghan, Marie F Martinez, Allan Ciciriello, Sarah Kulkarni, Kavya Velmurugan, Alexis Dibbs, Sheryl A Scannell, Yanhan Shen, Denis Nash, Peter J Hotez, Bruce Y Lee

Faculty, Staff and Students Publications

Background: Long coronavirus disease (COVID), which affects an estimated 44.69-48.04 million people in the United States, is an ongoing public health concern that will persist as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread.

Methods: We developed a computational simulation model representing the clinical course, health effects, and associated costs of a person with long COVID.

Results: Simulations show that the average total cost of a long COVID case can range from $5084-$11 646 (assuming symptoms only last 1 year) with 92.5%-95.2% of these costs being productivity losses. Therefore, the current number of long COVID cases could cost …

Host Plant Resistance To Stink Bugs In Commercial Soybean Varieties, Cristofer Martinez

LSU Master's Theses

Soybean, Glycine max (L.) Merr. (Fabales: Fabaceae), is a major crop in Louisiana, where stink bugs (Hemiptera: Pentatomidae) are economically important pests that reduce seed quality and yield. Among them, the redbanded stink bug, Piezodorus guildinii (Westwood), is considered the most damaging species in the southern U.S. soybean system. Recently, Euschistus quadrator (Rolston), historically a minor pest, has increased in abundance and now dominates the brown stink bug complex in Louisiana soybean fields. While P. guildinii has been widely studied, little is known about E. quadrator.

Given the increasing pest complexity, sustainable management strategies are needed to target …

Unveiling The Clinicopathological Outcomes Of Breast Cancer In Young Women: A Perspective From Resource-Limited Settings, Kulsoom Shaikh, Aiman Arif, Mehwish Mooghal, Lubna Vohra

Sultan Qaboos University Medical Journal

Objectives: This study aimed to assess the incidence of breast cancer in young women over a ten-year period and examine its association with clinical characteristics, risk factors, treatment modalities, and survival outcomes. Methods: A retrospective analysis of the Breast Cancer Registry at our institution was conducted. Of the 2,238 women diagnosed with breast cancer between 2012 and 2021, 535 (23.9%) were aged 40 years or younger at the time of diagnosis. Cases with missing data for independent variables were excluded from the respective analyses. Results: The mean age at diagnosis was 34.5 years (range: 15–40). The most common clinical …

High Glucose In Diabetic Hyperglycemia Perturbs Lymphocyte Serca-Regulated Ca2+ Stores With Accompanying Er Stress And Signaling Dysfunction, Md N. Uddin, James L. Graham, Peter J. Havel, Roshanak Rahimian, David W. Thomas

Pacific Faculty Work

It is well recognized that patients with type 2 diabetes mellitus (T2DM) exhibit significant impairment of immune function resulting in a higher frequency of infections. We hypothesize in this study that a likely contributor to immune dysfunction in T2DM is alteration of T lymphocyte signaling functions induced by chronic hyperglycemia. In this study we have utilized the established UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) rat model of human T2DM to investigate whether progressive hyperglycemia diminishes T cell receptor (TCR)-releasable endoplasmic reticulum (ER) Ca²⁺ stores, an essential early antigen-stimulated signal driving T cell activation. Furthermore, results from this study …

Preparation And Properties Of Rutin-Casein Complexes, Zhang Nan, Liu Lili, Yang Le, Li Sisi, Zhang Xinyuan

Food and Machinery

［Objective］ To investigate the effect of complexes produced by protein -polyphenol interaction on the bioavailability of polyphenols and proteins.［Methods］ Rutin -casein complexes are prepared using rutin and casein as raw materials.Their physicochemical and structural properties are analyzed.［Results］］ The optimal preparation conditions for the rutin -casein complexes are determined as follows:mass ratio of rutin to casein =1.89∶1.00,reaction time of 5.94 h,pH 8.5,and temperature of 50 ℃.Under such conditions,the binding degree is 40.23%.Compared with casein,the complexes exhibit a decrease in emulsifying activity index (8.47 m2/g) and emulsifying stability (9.39%).The solubility increases by 5.11%,surface hydrophobicity is significantly enhanced,and antioxidant activity markedly improves (P<0.05).Scanning electron microscopy reveals that the rutin -casein complexes display a lamellar structure with smooth surfaces,which may contribute to its functional properties.Infrared spectroscopy demonstrates peak broadening and redshifts in the amide I and II bands,and fluorescence intensity (including synchronous fluorescence ) decreases due to fluorescence quenching.It indicates that rutin alters the secondary structure and conformational arrangement of casein.［Conclusion］ Compared with the uncomplexed casein,the rutin -casein complexes are enhanced in solubility,surface hydrophobicity,and antioxidant activity.引用格式：张楠，刘丽莉，杨乐，等.芦丁—酪蛋白复合物的制备及特性研究 ［J］.食品与机械，2025，41（7）：9-17.C itation:ZHANG Nan,LIU Lili,YANG Le,et al.Preparation and properties of rutin-casein complexes [J].Food & Machinery,2025,41(7):9-17.

Effects Of Sodium Chloride Treatment On The Functional Characteristics And Structure Of Porcine Plasma Protein, Wang Deqiang, Zhao Longyuan, Tang Huaijian, Ma Yihao, Jia Feng

Food and Machinery

［Objective］ To explore the effects of sodium chloride (NaCl ) on the functional and structural properties of porcine plasma proteins (PPP),with the aim of providing a reference for the practical application of PPP.［Methods］ PPP was treated with different concentrations of NaCl (0~1.0 mol/L ),and changes in its functional and structural properties were measured using ultraviolet -visible spectrophotometry,laser particle size analysis,and Zeta potential analysis.［Results］］ NaCl promoted the solubility of PPP,reaching a peak at 0.2 mol/L.With further increases in NaCl concentration,solubility showed a downward trend.The trends in surface hydrophobicity and emulsifying properties of PPP changed at 0.8 mol/L,with maximum increases of 69.75% …

Effects Of Electron Beam Irradiation On Carotenoids And Capsaicinoids In Pepper Oils Prepared By Different Plant Oils, Ouyang Mengyun, Li Wenge, Cao Sheng, Mo Mo, Zhou Yiji, Zhang Qiling, Xu Yuanfang

Food and Machinery

［Objective］ To investigate the irradiation stability of carotenoids and capsaicinoids in pepper oils prepared using different plant oils.［Methods］ With rapeseed oil (RO),soybean oil (SO),and their blended oil (RSO ) as materials,pepper oils RO -P,SO-P,and RSO -P were prepared,and subjected to high -energy electron beam irradiation (10 MeV ).The effects of different irradiation doses (4~12 kGy ) on the peroxide value (PV),acid value (AV),carotenoid content,and capsaicinoid content of the pepper oils were investigated.［Results］］ Electron beam irradiation promoted lipid oxidation in the pepper oils,resulting in increased PV and AV values,with SO -P exhibiting the highest degree of lipid oxidation.When the irradiation dose …

Mir-302a/B/D-3p Differentially Expressed During Frontonasal Development Is Sensitive To Retinoic Acid Exposure, Chihiro Iwaya, Akiko Suzuki, Goo Jun, Junichi Iwata

Faculty, Staff and Student Publications

Any failure in frontonasal development can lead to malformations at the middle facial region, such as frontonasal dysplasia, midfacial clefts, and hyper/hypotelorism. Various environmental factors influence morphogenesis through epigenetic regulations, including the action of noncoding microRNAs (miRNAs). However, it remains unclear how miRNAs are involved in the frontonasal development. In our analysis of publicly available miRNA-seq and RNA-seq datasets, we found that miR-28a-5p, miR-302a-3p, miR-302b-3p, and miR-302d-3p were differentially expressed in the frontonasal process during embryonic days 10.5 to 13.5 (E10.5–E13.5) in mice. Overexpression of these miRNAs led to a suppression of cell proliferation in cultured mouse embryonic frontonasal mesenchymal …

Investigation Of The Interaction Between Diethyl Phthalate And Ovalbumin Via Spectroscopic Techniques And Molecular Docking, Fu Chen, Huang Qun

Food and Machinery

［Objective］ To explore the interaction mechanism between diethyl phthalate (DEP ) and ovalbumin (OVA ) using multispectral analysis and molecular docking techniques.［Methods］ The Stern -Volmer equation is applied to study the fluorescence quenching mechanism of OVA by DEP,as well as to determine the binding constants and the number of binding sites between them.Thermodynamic parameters are used to identify the primary types of interaction forces.Based on Förster's non -radiative energy transfer theory,the energy transfer efficiency and binding distance between DEP and OVA are calculated.Molecular docking simulations are used to investigate the interaction forces between DEP and OVA.［Results］］ DEP can statically quench …

Ultrasound-Assisted Enzymatic Extraction And Structural Characterization Of Pectin From The Tender Leaves Of Abelia Macrotera, Mao Qiqi, Luo Yang, Wang Jianglin, Luo Jie, Fan Xiankang, Liu Chengguo, Zhou Hui

Food and Machinery

［Objective］ To clarify the physicochemical properties,microscopic structure,monosaccharide composition,relative molecular mass,and structural characteristics of pectin in the tender leaves of Abelia macrotera.［Methods］ Pectin from the tender leaves of Abelia macrotera was extracted by ultrasound -assisted cellulase method.The microscopic structure was observed under scanning electron microscope.The monosaccharide composition was determined by high performance liquid chromatography.The relative molecular mass was determined by polysaccharide hydrolysis derivatization.The possible structure was inferred by infrared spectroscopy.［Results］］ The yield of pectin from the tender leaves of Abelia macrotera is 23.38%,the esterification degree was 1.17%,and the galacturonic acid content was 72.16%.The pectin is in the form of flakes with …

High-Performance Liquid Chromatography-Tandem Mass Spectrometry For Determination Of Milk Fat Globule Membrane Proteins In Raw Milk Powder, Liu Jianping, Wang Meiling, Cheng Jing, Wang Lin, Zhang Fan, Li Guangsheng, Liu Yang, Fang Jing, Liu Xiangrong

Food and Machinery

［Objective］ To establish a method for the quantitative detection of milk fat globule membrane proteins in raw milk powder based on characteristic peptides using liquid chromatography -tandem mass spectrometry.［Methods］ Characteristic peptides are selected from the proteolytic products of milk fat globule membrane proteins.The quantification of milk fat globule membrane proteins in raw milk powder is performed using multiple reaction monitoring mode.Isotope -labeled internal standard peptides are synthesized to reduce matrix effects and compensate for losses during sample preparation.［Results］］ The method's quantification limits range from 0.234 to 0.811 mg/g.The recovery rates at low,medium,and high spiked levels are 82.5% to 105.6%,with relative …

Preparation And Performance Of Visual Active Film By Purple Yam, Deng Fuyuan, Xie Wei, Li Xin, Wen Yanqing, Zhu Guiting

Food and Machinery

［Objective］ This study aimed to develop a visual active film using the inherent anthocyanins in purple yam as a natural indicator and its rich content of starch,polysaccharides,and proteins as the film -forming matrix,providing an intuitive and effective new approach for quality control of fish products.［Methods］ Purple yam was processed by raw,steamed,and boiled treatments,then freeze -dried to obtain three types of purple yam powders,which were used to prepare visual active films corresponding to each treatment method.The effects of different citric acid additions on film properties were investigated.Based on comprehensive analysis of film characteristics,the optimal active film was selected and applied for …

Effects Of Three Cryoprotectants On Freeze-Thaw Qualities Of Shrimp Paste, Chen Jiangping, Huang Jianlian, Zhong Qian, Chen Hui

Food and Machinery

［Objective］ To compare the effects of three cryoprotectants on the freezing resistance improvement of shrimp paste.［Methods］ Shrimp paste samples are prepared.After three consecutive freeze -thaw cycles,the following indicators are determined in the samples:gel strength,energy storage modulus,salt -soluble protein content,sulfhydryl group content,viscosity,and microstructure,to compare the quality change of shrimp paste added with trehalose,sorbitol,and cod scale collagen peptide after repeated frozen -thaw.［Results］］ The gel strength and sulfhydryl group content in the cod scale collagen peptide group are higher than those in the trehalose and sorbitol group,with smoother structures and more uniform pore sizes.Besides,the viscosity of the cod scale collagen peptide group is …

Optimization Of Sulfur-Free Color Protection Process And Comparison Of Drying Techniques For Honeysuckle, Zhai Yumei, Tang Xiaojuan, Fu Xiao, Gong Min, Liu Yunguo

Food and Machinery

［Objective］ To develop green processing technology to inhibit the browning of fresh honeysuckle (Lonicera japonica Thunb ) and enhance its drying quality.［Methods］ With polyphenol oxidase relative enzyme activity and color difference values as evaluation indicators,the process of sulfur -free compound color -protecting agents (citric acid,D-sodium erythorbate,and DL-sodium malate ) is optimized through response surface methodology.Additionally,the effect of various drying methods,including vacuum freeze drying and microwave drying,on the quality after color protection is compared and analyzed.［Results］］ Citric acid demonstrates the best anti -browning effect.The process parameters are optimal when citric acid concentration is 0.105 mol/L,with D-sodium erythorbate concentration of 0.124 mol/L …

Antioxidant Activity And Molecular Mechanisms Of Typical Flavonoids In Dendrobium Officinale, Wang Yixue, Qin Si, Zhou Runze, Lyu Chenghao

Food and Machinery

［Objective］ To explore the antioxidant activity and molecular mechanism of the typical flavonoid apigenin and its glycoside compounds in Dendrobium officinale.［Methods］ The antioxidant activities of apigenin and its glycoside compounds were assessed using the DPPH free radical scavenging assay,and their effects on the expression of antioxidant proteins in HepG 2 cells were examined by Western blot.［Results］］ Vitexin exhibited significantly stronger antioxidant activity than apigenin and New Zealand vitexin Ⅱ,with an IC50 value for DPPH radical scavenging of 43.48 mmol/L.MTT assays confirmed that apigenin (20 μmol/L ),vitexin,and New Zealand vitexin Ⅱ (80 μmol/L ) were non -toxic to HepG 2 cells.In …

Effect Of High Hydrostatic Pressure Technology On Quality And Phenylethanoid Glycoside Extraction Amount Of Freshly Cut Desert Cistanche, Shi Shuo, Li Qingxin, Eerdun Bayaer, Xu Wanping, Dong Tungalag, Yun Xueyan

Food and Machinery

［Objective］ To explore the effect of the pressure,time,and section thickness of high hydrostatic pressure treatment on the quality and phenylethanoid glycoside extraction amount of desert cistanche.［Methods］ The application parameters of high hydrostatic pressure treatment for cistanch are optimized by single factor experiment combined with response surface optimization.［Results］］ The results of single factor optimization show that with the increase of pressure (100~500 MPa ) and treatment time (10~25 min ),the color difference,hardness,and phenylethanoid glycoside extraction amount of cistanche are increased.With the increase of section thickness (2~10 mm ),the color difference of cistanche is increased,but the hardness and phenylethanoid glycoside extraction amount …

Synergistic Depolymerization Of Polymeric Proanthocyanidins From Vitis Amurensis Seeds By Catechin And Sulfurous Acid And Their Antioxidant Activity, Lan Jing, Ren Xiangyun, Su Hao, Pang Jie, Li Weixin

Food and Machinery

［Objective］ To address the problem of low bioavailability of polymeric proanthocyanidins (PPCs ).［Methods］ PPCs extracted,isolated,and purified from Vitis amurensis seeds were used as the raw materials.The average degree of polymerization (mDP ) was used as the evaluation index.Catechin (C) combined with sulfurous acid was employed as the depolymerization reagent.The effects of the catechin -to-PPC mass ratio (mC∶mPPC),sulfurous acid amount,reaction time,and temperature on mDP were studied.The depolymerization process was optimized using response surface methodology,and the antioxidant activity of PPC before and after depolymerization was analyzed.［Results］］ Catechin combined with sulfurous acid effectively depolymerized PPC from V.amurensis seeds.The optimal depolymerization conditions were as …

Protective Effects Of Lactobacillus Rhamnosus Cqfp 202412 On The Brain , Intestines , And Motor Functions Of Antibiotic-Damaged Mice, Cheng Bo, Li Chong, Meng Xianlu

Food and Machinery

［Objective］ To explore the effects of Lactobacillus rhamnosus CQFP 202412 on improving the intestinal barrier,liver,brain neurons,and motor function in mice through its antioxidant and anti -inflammatory activities.［Methods］ A mouse model was established by intraperitoneal injection of a mixed antibiotic solution (neomycin 5 mg/mL,vancomycin 25 mg/mL,amphotericin B 0.1 mg/mL,ampicillin 10 mg/mL,metronidazole 5 mg/mL,and lipopolysaccharide 1.5 μg/mL ),followed by intervention with L.rhamnosus CQFP 202412.After the intervention,weight -loaded swimming time and running exhaustion time were measured,along with liver index and oxidative stress/inflammatory markers in serum and brain tissue.Histopathological changes in the brain were observed by HE staining,and PCR was used to detect the …

Lipid-Lowering Effect And Mechanism Of Walnut Oil, Xie Shanshan, Chen Wenli, Cui Shuchun

Food and Machinery

［Objective］ To study the effect of walnut oil on lipid metabolism and elucidate its mechanism of action.［Methods］ A high -fat diet is used to establish a high -fat model of SD rats,and 500,1 000,and 1 500 mg/kg undiluted walnut oil is used for gavage intervention experiments.After 8 weeks of intervention,the changes in body weight,organ indexes,serum lipid biochemical indicators,and serum antioxidant related indicators of SD rats are measured to observe the effects of walnut oil on organs,blood lipids,and antioxidant capacity.The expression of ABCA 1 mRNA,ABCG 1 mRNA,and SREBP 2-HMGCR signaling pathway and PPAR α-LXRα-CYP 7A1 signaling pathway genes in rat liver …

Anti-Fatigue Activity Of Lycium Barbarum Polysaccharides, Sun Xin, Fan Shijun

Food and Machinery

［Objective］ To clarify the main components of Lycium barbarum polysaccharides that exert an anti -fatigue effect.［Methods］ Lycium barbarum polysaccharides with different relative molecular weights are prepared by water extraction,ultrafiltration membrane fractionation dialysis,and other methods.The components with good anti -fatigue activity are obtained by mice burden swimming test.They are then eluted and purified by ion exchange column and gel chromatography column to determine the relative molecular weights and monosaccharide components.The infrared spectrum is employed to analyze.［Results］］ The content of polysaccharide,protein,and uronic acid in Lycium barbarum polysaccharides with different molecular weights is 63.62%~75.63%,1.77%~2.63%,and 17.77%~24.77%,respectively.The LBP 2 has a higher component yield.The relative …