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Articles 5911 - 5940 of 933490
Full-Text Articles in Entire DC Network
Breaking The Ideal: Viscosity, Nonlinearity, And Transience In Wave Attractors, Stepan Elistratov, Ivan But
Breaking The Ideal: Viscosity, Nonlinearity, And Transience In Wave Attractors, Stepan Elistratov, Ivan But
Turkish Journal of Physics
Wave attractors in viscous media exhibit laminar or turbulent behavior, dictated by the intensity of the external forcing. Laminar attractors are often assumed to behave as linear systems. However, existing studies typically focus on fully developed flows, neglecting the dynamic formation process of these attractors. This simplification overlooks crucial transient phenomena that govern their emergence and stability. In this paper, first, we investigate unconventional wave attractor configurations subjected to forcing with a complex spectrum, which lead to early nonlinearity demonstration. Next, we focus on the transient processes of attractor formation and destruction, providing insights into their dynamic evolution. Furthermore, we …
Book Review - Violent Impacts: How Power And Inequality Shape The Concussion Crisis, Samuel M. Clevenger
Book Review - Violent Impacts: How Power And Inequality Shape The Concussion Crisis, Samuel M. Clevenger
Global Sport Business Journal
Kathryn Henne and Matt Ventresca’s Violent Impacts critically examines how narratives surrounding CTE, TBI, and the concussion crisis are constructed across sport, the military, law, media, and science. Drawing on intersectional feminism and science and technology studies, the authors show how dominant concussion discourses privilege the experiences of White male athletes while marginalizing other groups. Based on extensive fieldwork, the book makes an important contribution by exposing representational inequalities and highlighting the intersectional gender politics of concussion research and public debate.
A Rho5-Cnc1-Dnm1 Signalling Module Coordinates Multi-Organelle Execution Of Regulated Cell Death In Yeast, Justin Bauer
A Rho5-Cnc1-Dnm1 Signalling Module Coordinates Multi-Organelle Execution Of Regulated Cell Death In Yeast, Justin Bauer
Theses and Dissertations
Regulated cell death is a conserved process with major implications for health and disease, yet how yeast cells integrate stress signals to determine survival versus death remains unclear. This thesis investigates Cyclin C (Cnc1), a conserved Mediator kinase module component with both transcriptional and mitochondrial roles. Together with Cdk8 Cnc1 primarily represses stress response genes, while upon stress it translocates to the mitochondria to induce mitochondrial fragmentation with the dynamin-related GTPase Dnm1. Using structure-guided separation-of-function mutants, I demonstrate that Cnc1-dependent death requires its mitochondrial function rather than its transcriptional role, and that its effector Dnm1 acts as a signaling node …
Extracurricular Video Game Use And Academic Achievement: A Systematic Literature Review, Christina Hartman, Theo Makanoa, Lucas Thoms, Aidan Lowry, Kaleb Chandler
Extracurricular Video Game Use And Academic Achievement: A Systematic Literature Review, Christina Hartman, Theo Makanoa, Lucas Thoms, Aidan Lowry, Kaleb Chandler
English Student Research
A good deal of research exists on the relationship between student use of video games outside the classroom and academic achievement. Our systematic review aims to identify what patterns exist across research conducted in the last 20 years. We examined 62 research studies that dealt with academic achievement and extracurricular video game use and found that most studies identify a negative association between the two. However, this isn’t the case for all students. We identified three important variables (the amount of time spent playing video games, the time of day or week spent playing, and the age of the students) …
June 16, 2026 Ereporter, University Of Alabama At Birmingham
June 16, 2026 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Book Review - California And The Making Of Modern Sport, Sean Burke
Book Review - California And The Making Of Modern Sport, Sean Burke
Global Sport Business Journal
Joel S. Franks’s California and the Making of Modern Sport argues that California helped shape modern sport as spectacle, consumer culture, and civic branding. review highlights the strengths in linking iconic sites such as the Rose Bowl, Muscle Beach, Fresno baseball, Billie Jean King, and the 1932 Los Angeles Olympics to broader themes of commercialization, diversity, and inequality. Drawing on historical sources, Franks demonstrates how sport in California produced modern sporting culture and its contradictions.
Skin Cancer Surgery Under Local Anesthesia: Clinicopathologic Characteristics And Age-Stratified Outcomes In 533 Patients, Menekşe Kastamoni̇ Başkan, Süleyman Çeçen, Selçuk Akin, Şaduman Balaban Adim, Güzi̇n Yeşi̇m Özgenel
Skin Cancer Surgery Under Local Anesthesia: Clinicopathologic Characteristics And Age-Stratified Outcomes In 533 Patients, Menekşe Kastamoni̇ Başkan, Süleyman Çeçen, Selçuk Akin, Şaduman Balaban Adim, Güzi̇n Yeşi̇m Özgenel
Turkish Journal of Medical Sciences
Background/aim: Skin cancer is the most common malignancy worldwide, particularly among elderly individuals. Many lesions are detected at an early stage because of their visibility and can be excised under local anesthesia, thereby avoiding the risks associated with general anesthesia or sedation. This study aimed to evaluate patient- and tumor-related characteristics in skin cancer surgery performed under local anesthesia, with particular emphasis on age-related outcomes.
Materials and methods: This retrospective study included 533 patients with 613 histopathologically confirmed skin cancers excised under local anesthesia between 2019 and 2024. Demographic, histopathological, and surgical variables were recorded, including age, sex, tumor location, …
Long-Term Outcomes Of Lamellar Crescentic Wedge Resection On Corneal Astigmatism And Optical Aberrations In Patients With Advanced Pellucid Marginal Degeneration, Ayşe Burcu, Hande Hüsni̇ye Telek, Hakan Mert, Yaprak Arzu Özdemi̇r, Züleyha Yalniz Akkaya, Evi̇n Şi̇ngar, Selma Özbek Uzman
Long-Term Outcomes Of Lamellar Crescentic Wedge Resection On Corneal Astigmatism And Optical Aberrations In Patients With Advanced Pellucid Marginal Degeneration, Ayşe Burcu, Hande Hüsni̇ye Telek, Hakan Mert, Yaprak Arzu Özdemi̇r, Züleyha Yalniz Akkaya, Evi̇n Şi̇ngar, Selma Özbek Uzman
Turkish Journal of Medical Sciences
Background/aim: The present study investigates the long-term changes in corneal astigmatism and aberrations following lamellar wedge resection in cases with advanced pellucid marginal degeneration (PMD).
Materials and methods: Patients with advanced PMD whose visual acuity did not improve with glasses or contact lenses underwent lamellar crescentic wedge resection. Pre- and postoperative assessments at 3, 6, 12, and 24 months using Pentacam HR were conducted to identify changes in corrected visual acuity, corneal astigmatism, and higher-order aberrations (HOAs) following the procedure, and compared with a control group.
Results: Statistically significant postoperative improvements in corrected visual acuity were observed at 6 and …
Effects Of Repetitive Peripheral Magnetic Stimulation On Poststroke Ankle Spasticity: A Double-Blind Randomized Controlled Trial, Hüseyi̇n Oğuzhan Aslantaş, Şehi̇m Kutlay, Haydar Gök, Semra Özkan, Seçi̇lay Güneş, Ati̇lla Hali̇l Elhan
Effects Of Repetitive Peripheral Magnetic Stimulation On Poststroke Ankle Spasticity: A Double-Blind Randomized Controlled Trial, Hüseyi̇n Oğuzhan Aslantaş, Şehi̇m Kutlay, Haydar Gök, Semra Özkan, Seçi̇lay Güneş, Ati̇lla Hali̇l Elhan
Turkish Journal of Medical Sciences
Background/aim: Repetitive peripheral magnetic stimulation (rPMS) is a noninvasive, painless therapy aimed at improving spasticity, with a proposed mechanism that involves neuromodulation through somatosensory and proprioceptive afferent stimulation. The present study evaluates the effectiveness of rPMS on ankle plantar flexor spasticity in participants with stroke.
Materials and methods: Included in this prospective, double-blind, randomized, sham-controlled study were 50 participants with poststroke ankle plantar flexor spasticity graded 1–3 according to Modified Ashworth Scale (MAS). Participants were randomized into rPMS (n = 25) and sham (n = 25) groups. All participated in a conventional rehabilitation program, while the rPMS group received 10 …
Serum Angiopoietin-1 And Angiopoietin-2 Levels In Turkish Patients With Behçet’S Disease: Associations With Clinical Manifestations And Inflammatory Markers, Sercan Gücenmez, Hakan Emmungi̇l, Fi̇gen Yargucu Zi̇hni̇, Gökhan Keser, Kenan Aksu
Serum Angiopoietin-1 And Angiopoietin-2 Levels In Turkish Patients With Behçet’S Disease: Associations With Clinical Manifestations And Inflammatory Markers, Sercan Gücenmez, Hakan Emmungi̇l, Fi̇gen Yargucu Zi̇hni̇, Gökhan Keser, Kenan Aksu
Turkish Journal of Medical Sciences
Background/aim: Emerging evidence suggests that dysregulated angiogenesis may contribute to the pathogenesis of Behçet’s disease (BD). This study primarily aimed to investigate serum angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) levels in Turkish patients with BD and compare them with healthy controls. The secondary aims were to compare angiopoietin levels based on clinical manifestations, disease activity, and medication use and to investigate their correlations with age, disease duration, and inflammatory markers.
Materials and methods: This cross-sectional study included 56 consecutive patients with BD, diagnosed according to International Study Group criteria, and 56 age- and sex-matched healthy controls. Physical characteristics, clinical manifestations, time …
Comprehensive Geriatric Assessment Identifies Multidimensional Vulnerabilities In Older Adults With Heart Failure, Ci̇han Kiliç, Rengi̇n Demi̇r, Özlem Yilmaz Aykent, Zerri̇n Yi̇ği̇t, Pinar Küçükdağli, Banu Özulu Türkmen, Güli̇stan Bahat, Mehmet Aki̇f Karan
Comprehensive Geriatric Assessment Identifies Multidimensional Vulnerabilities In Older Adults With Heart Failure, Ci̇han Kiliç, Rengi̇n Demi̇r, Özlem Yilmaz Aykent, Zerri̇n Yi̇ği̇t, Pinar Küçükdağli, Banu Özulu Türkmen, Güli̇stan Bahat, Mehmet Aki̇f Karan
Turkish Journal of Medical Sciences
Background/aim: Heart failure (HF) in older adults is frequently accompanied by geriatric syndromes that remain unrecognized in conventional cardiac evaluations. The vulnerabilities of older adults with and without HF in terms of muscle strength, physical performance, functional capacity, frailty, nutritional status, cognition, mood, anxiety, polypharmacy, and comorbidity were investigated using comprehensive geriatric assessment (CGA).
Materials and methods: A cross-sectional study was conducted in two academic outpatient clinics, enrolling 420 adults aged ≥60 years, including 92 (21.9%) with HF. Data included sociodemographic characteristics, anthropometric measurements, and CGA parameters: handgrip strength, the Five-Times Sit-to-Stand Test (FTSST), the Short Physical Performance Battery (SPPB), …
Comparison Of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block And Thoracic Paravertebral Block For Postoperative Analgesia After Breast Surgery: A Prospective Randomized Noninferiority Trial, Mustafa Sirri Kotanoğlu, Musa Zengi̇n, Onur Küçük, Atakan Sezgi̇, İbrahi̇m Topcu, Aras Meti̇n, Zeynep Ersoy, Jüli̇de Ergi̇l
Comparison Of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block And Thoracic Paravertebral Block For Postoperative Analgesia After Breast Surgery: A Prospective Randomized Noninferiority Trial, Mustafa Sirri Kotanoğlu, Musa Zengi̇n, Onur Küçük, Atakan Sezgi̇, İbrahi̇m Topcu, Aras Meti̇n, Zeynep Ersoy, Jüli̇de Ergi̇l
Turkish Journal of Medical Sciences
Background/aim: This noninferiority trial aimed to evaluate whether the serratus posterior superior intercostal plane block (SPSIPB) provides noninferior postoperative analgesia compared with the thoracic paravertebral block (TPVB) after unilateral mastectomy.
Materials and methods: This prospective, randomized, assessor-blinded, parallel-group noninferiority trial enrolled 60 female patients scheduled for elective unilateral mastectomy. Patients received either ultrasound-guided SPSIPB (n = 30) or TPVB (n = 30) with 30 mL of 0.25% bupivacaine before induction. The primary outcome was visual analogue scale (VAS) pain scores (0–100 mm) at rest and during coughing over 24 h. Noninferiority was assessed using the Hodges–Lehmann median difference with 95% …
Timing Of Kirschner Wire Removal In Pediatric Supracondylar Humerus Fractures: Is Early Removal A Safe And Effective Option?, Mustafa Kemal Yeni̇dünya, Si̇nan Yüksel, İbrahi̇m Faruk Adigüzel, Serhat Di̇nç, Önder Ersan
Timing Of Kirschner Wire Removal In Pediatric Supracondylar Humerus Fractures: Is Early Removal A Safe And Effective Option?, Mustafa Kemal Yeni̇dünya, Si̇nan Yüksel, İbrahi̇m Faruk Adigüzel, Serhat Di̇nç, Önder Ersan
Turkish Journal of Medical Sciences
Background/aim: The optimal timing of Kirschner wire removal following the surgical treatment of pediatric supracondylar humerus fractures remains controversial. This study aimed to compare the clinical and radiographic outcomes of early versus late K-wire removal and to contribute to the standardization of the timing of pin removal in pediatric patients.
Materials and methods: This retrospective study included 90 pediatric patients (aged 4–14 years) treated with closed reduction and percutaneous pinning for Gartland type III and IV supracondylar humerus fractures. Patients were grouped according to the timing of pin removal as early (postoperative days 21–28, n = 40) or late (after …
Urinary Dkk3 As A Predictor Of Ckd Stages In Reflux Nephropathy In Children, Ayşe Seda Pinarbaşi, Nesli̇han Günay, İnayet Güntürk, Di̇dem Barlak Keti̇, Si̇bel Yel, Sekure Rabi̇a Ulueren, Cevat Yazici, Muammer Hakan Poyrazoğlu, İsmai̇l Dursun
Urinary Dkk3 As A Predictor Of Ckd Stages In Reflux Nephropathy In Children, Ayşe Seda Pinarbaşi, Nesli̇han Günay, İnayet Güntürk, Di̇dem Barlak Keti̇, Si̇bel Yel, Sekure Rabi̇a Ulueren, Cevat Yazici, Muammer Hakan Poyrazoğlu, İsmai̇l Dursun
Turkish Journal of Medical Sciences
Background/aim: Reflux nephropathy is an important cause of chronic kidney disease (CKD) in children. The search for new biomarkers continues, as early intervention is important to slow the progression of CKD. Urinary Dickkopf-3 (uDKK3), a potential marker of tubulointerstitial fibrosis, has been studied in adults but not extensively in children with CKD. This study was conducted to determine the role of uDKK3 levels in predicting the CKD stage in children with reflux nephropathy.
Materials and methods: This cross-sectional study included 113 children with CKD stages 1–4 with reflux nephropathy and 28 healthy controls. uDKK3 concentrations were measured using enzyme-linked immunosorbent …
Non-Pulmonary Arterial Involvement In Behçet's Disease: A Multicentre Retrospective Case Series, Özge Karakök, Duygu Keri̇m, Şeri̇fe Çoşkun-Sağirkaya, Gamze Akkuzu, Burcu Ceren Uludoğan, Gezmi̇ş Ki̇myon, Hasan Kocaayan, Senar Şan, Özkan Urak, Gökçe Kenar, Ayşe Cefle, Servet Akar, Nazi̇fe Şule Yaşar-Bi̇lge, Cemal Bes, Şükran Erten, Ahmet Omma, Gökhan Keser, Kenan Aksu, Tüli̇n Ergun, Rafi̇ Haner Di̇reskeneli̇, Fatma Ali̇baz-Öner
Non-Pulmonary Arterial Involvement In Behçet's Disease: A Multicentre Retrospective Case Series, Özge Karakök, Duygu Keri̇m, Şeri̇fe Çoşkun-Sağirkaya, Gamze Akkuzu, Burcu Ceren Uludoğan, Gezmi̇ş Ki̇myon, Hasan Kocaayan, Senar Şan, Özkan Urak, Gökçe Kenar, Ayşe Cefle, Servet Akar, Nazi̇fe Şule Yaşar-Bi̇lge, Cemal Bes, Şükran Erten, Ahmet Omma, Gökhan Keser, Kenan Aksu, Tüli̇n Ergun, Rafi̇ Haner Di̇reskeneli̇, Fatma Ali̇baz-Öner
Turkish Journal of Medical Sciences
Background/aim: In Behçet’s disease (BD), arterial involvement represents a significant clinical challenge associated with serious complications. The present study evaluates the characteristic features, affected vessels, lesion types, treatments, and outcomes in BD patients with nonpulmonary arterial involvement.
Materials and methods: Included in this retrospective study were 65 BD patients whose interventions and clinical courses were accessed from medical records. The treatments administered included immunosuppressive (IS) therapies and surgical/endovascular procedures. Fisher’s exact and t-test/Mann–Whitney U test were used for statistical analysis.
Results: Fifty-nine of the patients (90.8%) were male. The median (Q1–Q3) follow-up was 4 (2–12.8) years. The most commonly affected …
Multiple Organ Dysfunction Syndrome In Pediatric Colchicine Poisoning: A National Cohort Study From Türkiye, Faruk Eki̇nci̇, Di̇nçer Yildizdaş, Ozden Özgür Horoz, Hayri̇ Levent Yilmaz, Sevcan Bi̇len, İlker Ünal, İkbal Türker, Esra Şevketoğlu, Ni̇hal Akçay, Agop Çitak, Güntülü Şik, Tanil Kendi̇rli̇, Merve Havan, Murat Kangin, Mehmet Nur Talay, Nazi̇k Yener, Hati̇ce Albayrak, Edi̇n Botan, Utku Özer, Arzu Oto, Gürkan Bozan, Muhterem Duyu, Başak Nur Akyildiz, Nai̇me Gökay, Eli̇f Çeli̇k, Çapan Konca, Mutlu Uysal Yazici, Oğuz Dursun, Feyza İnceköy Gi̇rgi̇n, Hati̇ce Feray Ari, İlknur Arslan, Murat Özkale, Özlem Sandal, Merve Misirlioğlu, Hali̇l Keski̇n, Sadik Kaya, Arda Kilinç, Ferhat Sari, Fati̇h Akin, Ayşe Aşik, Ibrahi̇m Bi̇ngöl, Eda Turanli, Merve Boyraz, Ener Çağri Di̇nleyi̇ci̇, Mehmet Aki̇f Dündar, Selver Ceren Özcan, Aygül Kaya Akilli, Emi̇ne Akkuzu, Nazan Ülgen Tekerek, Ni̇lüfer Öztürk, Emrah Gün, Yasemi̇n Özkale, Nuretti̇n Onur Kutlu, Zeynelabi̇di̇n Öztürk
Multiple Organ Dysfunction Syndrome In Pediatric Colchicine Poisoning: A National Cohort Study From Türkiye, Faruk Eki̇nci̇, Di̇nçer Yildizdaş, Ozden Özgür Horoz, Hayri̇ Levent Yilmaz, Sevcan Bi̇len, İlker Ünal, İkbal Türker, Esra Şevketoğlu, Ni̇hal Akçay, Agop Çitak, Güntülü Şik, Tanil Kendi̇rli̇, Merve Havan, Murat Kangin, Mehmet Nur Talay, Nazi̇k Yener, Hati̇ce Albayrak, Edi̇n Botan, Utku Özer, Arzu Oto, Gürkan Bozan, Muhterem Duyu, Başak Nur Akyildiz, Nai̇me Gökay, Eli̇f Çeli̇k, Çapan Konca, Mutlu Uysal Yazici, Oğuz Dursun, Feyza İnceköy Gi̇rgi̇n, Hati̇ce Feray Ari, İlknur Arslan, Murat Özkale, Özlem Sandal, Merve Misirlioğlu, Hali̇l Keski̇n, Sadik Kaya, Arda Kilinç, Ferhat Sari, Fati̇h Akin, Ayşe Aşik, Ibrahi̇m Bi̇ngöl, Eda Turanli, Merve Boyraz, Ener Çağri Di̇nleyi̇ci̇, Mehmet Aki̇f Dündar, Selver Ceren Özcan, Aygül Kaya Akilli, Emi̇ne Akkuzu, Nazan Ülgen Tekerek, Ni̇lüfer Öztürk, Emrah Gün, Yasemi̇n Özkale, Nuretti̇n Onur Kutlu, Zeynelabi̇di̇n Öztürk
Turkish Journal of Medical Sciences
Background/aim: Colchicine poisoning has been associated with systemic toxicity, multiple organ dysfunction syndrome (MODS), and mortality. In the present study, the demographic, clinical, and laboratory characteristics of pediatric colchicine poisoning cases and the incidence of organ failure are investigated to identify potential risk factors associated with MODS.
Materials and methods: Included in this retrospective multicenter cohort study were pediatric patients admitted to 28 tertiary-care pediatric intensive care units with a diagnosis of colchicine poisoning. Demographic data, clinical and laboratory findings, and clinical outcomes were extracted from medical records. MODS was defined as dysfunction involving at least two organ systems. Multivariable …
Association Of Vitamin D, Oxidative Stress Markers, And Hormonal Factors With Male Infertility: A Case-Control Study In Pakistan, Muhammad Tayyab Ihsan, Ayesha Ali Malick, Sher Khan, Sher Khan, Muhammad Tahir Khan, Haq Nawaz Khan, Rehana Rehman
Association Of Vitamin D, Oxidative Stress Markers, And Hormonal Factors With Male Infertility: A Case-Control Study In Pakistan, Muhammad Tayyab Ihsan, Ayesha Ali Malick, Sher Khan, Sher Khan, Muhammad Tahir Khan, Haq Nawaz Khan, Rehana Rehman
Turkish Journal of Medical Sciences
Background/aim: Infertility impacts around 15% of couples worldwide, with male factors accounting for approximately 50% of cases. Despite this significant share, male infertility remains understudied, particularly in developing nations such as Pakistan. The present study explores the association between male infertility and seminal plasma concentrations of oxidative stress markers, inhibin B, and vitamin D, along with their relationship with sperm parameters.
Materials and methods: The dataset of the study consisted of seminal plasma levels from 30 fertile and 60 infertile males. Total antioxidant capacity (TAC), Vitamin D, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), lipid peroxide (LPO), superoxide dismutase (SOD), and inhibin B …
Bridging The Methodological Gap In Multitrauma Literature: A Competency-Based Educational Framework And Clinical Appraisal Filter, Şaki̇r Hakan Aksu, Burcu Doğan, Merve Yazla
Bridging The Methodological Gap In Multitrauma Literature: A Competency-Based Educational Framework And Clinical Appraisal Filter, Şaki̇r Hakan Aksu, Burcu Doğan, Merve Yazla
Turkish Journal of Medical Sciences
Background/aim: The statistical complexity of contemporary multitrauma literature has increased considerably in recent years, which may pose challenges for clinicians seeking to interpret high-impact research and apply evidence-based practices. Characterizing this methodological landscape and exploring education-oriented approaches may help to improve the interpretability of the literature and support informed clinical decision-making.
Materials and methods: A cross-sectional analysis was conducted on the 100 most-cited multitrauma studies published in Science Citation Index Expanded journals indexed in the Web of Science database between January 2018 and November 2025. The statistical methods used in each article were categorized into the three competency levels of …
Common Femoral Vein Wall Thickness As A Supportive Imaging Marker In The Differential Diagnosis Of Behçet’S Uveitis, Seda Kutluğ Ağaçkiran, Esra Kardeş, Abdulbaki̇ Ağaçkiran, Haner Di̇reskeneli̇, Fatma Ali̇baz-Öner
Common Femoral Vein Wall Thickness As A Supportive Imaging Marker In The Differential Diagnosis Of Behçet’S Uveitis, Seda Kutluğ Ağaçkiran, Esra Kardeş, Abdulbaki̇ Ağaçkiran, Haner Di̇reskeneli̇, Fatma Ali̇baz-Öner
Turkish Journal of Medical Sciences
Background/aim: Ocular involvement is a major cause of morbidity in Behçet’s disease (BD), and its diagnosis may be challenging, particularly for patients with isolated ocular manifestations or incomplete fulfillment of diagnostic criteria. Increased common femoral vein (CFV) wall thickness measured by Doppler ultrasonography (US) has previously been shown to be a sensitive and specific marker for systemic BD. This study aimed to evaluate whether CFV wall thickness measurement may serve as a supportive tool in distinguishing Behçet’s uveitis (BU) from other forms of inflammatory uveitis.
Materials and methods: This retrospective study included 45 patients with BU fulfilling the International Study …
Clinical Outcomes Of Injectable And Conventional Pulmonary Valve Replacement In Severe Pulmonary Regurgitation, Sercan Tak, Murat Koç, Ali̇ Kutsal, Vehbi̇ Doğan
Clinical Outcomes Of Injectable And Conventional Pulmonary Valve Replacement In Severe Pulmonary Regurgitation, Sercan Tak, Murat Koç, Ali̇ Kutsal, Vehbi̇ Doğan
Turkish Journal of Medical Sciences
Background/aim: Pulmonary regurgitation following tetralogy of Fallot repair is a common long-term complication requiring pulmonary valve replacement. Injectable bioprosthetic valves offer a less invasive alternative to conventional surgical replacement, but comparative data in pediatric populations remain limited. This study aimed to evaluate short-term and long-term clinical outcomes of injectable pulmonary valve replacement and conventional pulmonary valve replacement in pediatric patients with severe pulmonary regurgitation following tetralogy of Fallot repair.
Materials and methods: This retrospective study included 22 pediatric patients who underwent pulmonary valve replacement. Patients were divided into injectable (n = 9) and conventional (n = 13) groups based on …
In Silico Evaluation Of The Role Of Pea3 Subfamily Ets Transcription Factors In Chemoresistance In Ovarian Cancer, Fevzi̇ Coşkun Sökmen, Lai̇ka Kardana, Hi̇kmet Yilmaz, Ahmet Çağlar Özketen, Aynur Karadağ Gürel, Özge Atay, Hasan Hüseyi̇n Kazan
In Silico Evaluation Of The Role Of Pea3 Subfamily Ets Transcription Factors In Chemoresistance In Ovarian Cancer, Fevzi̇ Coşkun Sökmen, Lai̇ka Kardana, Hi̇kmet Yilmaz, Ahmet Çağlar Özketen, Aynur Karadağ Gürel, Özge Atay, Hasan Hüseyi̇n Kazan
Turkish Journal of Medical Sciences
Background/aim: The E26 transformation-specific family of transcription factors regulates the cell cycle and apoptosis that are crucial for carcinogenesis. More specifically, the PEA3 subfamily—comprising ETS variant (ETV) transcription factors ETV1, ETV4, and ETV5—has been implicated in multiple oncogenic signaling pathways and chemotherapy resistance. While cisplatin is still a widely used chemotherapeutic treatment for ovarian cancer, its therapeutic efficacy is sometimes limited by the induction of resistance mechanisms. The present study investigates the potential role of PEA3 subfamily genes in cisplatin resistance in ovarian cancer through comprehensive in silico analyses.
Materials and methods: Cisplatin response data for ovarian cancer were obtained …
Omega-3–Rich Fish Oil Lipid Emulsions Significantly Prevent Sepsis-Driven Mesenteric Hypoperfusion And Multi-Organ Injury In Murine Models, Gökşen Öz, Esi̇n Özçelebi̇, Ayşe Yeşi̇m Göçmen, Cenk Sükmensüer, Selma Yildirim, Arzu Topeli̇, Alper Bektaş İski̇t
Omega-3–Rich Fish Oil Lipid Emulsions Significantly Prevent Sepsis-Driven Mesenteric Hypoperfusion And Multi-Organ Injury In Murine Models, Gökşen Öz, Esi̇n Özçelebi̇, Ayşe Yeşi̇m Göçmen, Cenk Sükmensüer, Selma Yildirim, Arzu Topeli̇, Alper Bektaş İski̇t
Turkish Journal of Medical Sciences
Background/aim: Parenteral feeding is used in critically ill patients when enteral nutrition is inadequate or intolerable, and the gastrointestinal tract is not functioning properly. Lipid emulsions play a major role in parenteral nutrition because they supply necessary fatty acids and a high-calorie density. We investigated the effects of parenteral lipid emulsions on mesenteric perfusion, inflammation-induced oxidation, and organ damage in lipopolysaccharide-induced mice endotoxemia model.
Materials and methods: In septic mice, organ damage induced by lipopolysaccharide was assessed by histopathology and biochemical examination. Additionally, an ultrasonic blood flowmeter was used to measure the impact of lipid emulsions on mesenteric blood flow. …
Optimistic And Ambivalent Attitudes Toward Clinical Artificial Intelligence, Sevi̇l Uygun İli̇khan, Si̇nem Ülke, Mahmut Özer, Matjaž Perc, Yavuz Ayhan
Optimistic And Ambivalent Attitudes Toward Clinical Artificial Intelligence, Sevi̇l Uygun İli̇khan, Si̇nem Ülke, Mahmut Özer, Matjaž Perc, Yavuz Ayhan
Turkish Journal of Medical Sciences
Background/aim: Artificial intelligence (AI) is increasingly being integrated into healthcare systems; however, healthcare professionals’ knowledge, attitudes, and perceptions regarding AI remain insufficiently understood. This study aimed to evaluate healthcare professionals’ perceptions of AI in clinical practice.
Materials and methods: This descriptive cross-sectional study included 260 healthcare professionals, including physicians, nurses, and healthcare technicians working at a tertiary public hospital in Türkiye. Participants completed the Healthcare Professionals and Artificial Intelligence Questionnaire, which assessed demographic characteristics, AI knowledge, workplace AI use, attitudes toward AI applications, ethical and legal concerns, perceived professional impact, and educational needs.
Results: Most participants reported limited AI knowledge; …
Hla Allele And Haplotype Diversity In Central Anatolia: A Comparative Analysis Of Donors And Transplant Candidates Across Six Hla Loci (Hla-A, Hla-B, Hla-C, Hla-Drb1, Hla-Dqb1, And Hla-Dpb1), Emel Yantir, Eren Gündüz, Ertuğrul Çolak
Hla Allele And Haplotype Diversity In Central Anatolia: A Comparative Analysis Of Donors And Transplant Candidates Across Six Hla Loci (Hla-A, Hla-B, Hla-C, Hla-Drb1, Hla-Dqb1, And Hla-Dpb1), Emel Yantir, Eren Gündüz, Ertuğrul Çolak
Turkish Journal of Medical Sciences
Background/aim: Human leukocyte antigen (HLA) polymorphisms play a central role in immune recognition, disease susceptibility, and transplant success. The distribution of HLA alleles and haplotypes varies among ethnic and geographic populations. Despite several regional studies conducted in Türkiye, large-scale and comprehensive investigations comparing HLA profiles between healthy individuals and transplant candidates remain limited. The aim of this study was to compare the distribution of HLA profiles among donors, hematopoietic stem cell transplantation (HSCT) candidates, and solid organ transplant candidates.
Materials and methods: A total of 8472 individuals were included in the study, comprising 6422 donors and 2050 transplant candidates. HLA …
Vnotes High Uterosacral Ligament Suspension Versus Laparoscopic Lateral Suspension In The Management Of Vaginal Vault Prolapse: Initial Experience In A Single Tertiary Center, Ramazan Adan, Fati̇h Şahi̇n, Ulya Üskent, Mehmet Gökhan Çulha, Arzu Bi̇lge Teki̇n
Vnotes High Uterosacral Ligament Suspension Versus Laparoscopic Lateral Suspension In The Management Of Vaginal Vault Prolapse: Initial Experience In A Single Tertiary Center, Ramazan Adan, Fati̇h Şahi̇n, Ulya Üskent, Mehmet Gökhan Çulha, Arzu Bi̇lge Teki̇n
Turkish Journal of Medical Sciences
Background/aim: The optimal technique for vaginal vault prolapse correction has yet to be identified. This study aimed to evaluate the anatomic and functional outcomes of women who underwent vaginal natural orifice transluminal endoscopic high uterosacral ligament suspension (vNOTES HUSLS) or laparoscopic lateral suspension (LLS).
Materials and methods: This retrospective study included symptomatic women with stage ≥2 vault prolapse who underwent vNOTES HUSLS or LLS between January 2019 and June 2022 at a tertiary center. The surgical efficacy, postoperative outcomes, complication rates, and recurrence frequencies of these procedures were compared. The primary outcomes of the study included anatomical success, patient-reported (subjective) …
Letter To The Editor: Telemedicine Versus Conventional Care For Nonspecific Neck Pain: A Randomized Controlled Study, Gülsemi̇n Ertürk Çeli̇k
Letter To The Editor: Telemedicine Versus Conventional Care For Nonspecific Neck Pain: A Randomized Controlled Study, Gülsemi̇n Ertürk Çeli̇k
Turkish Journal of Medical Sciences
No abstract provided.
Direct Minimization Of Hartree-Fock-Roothaan Energy Functionals Using Derivative-Free Optimization Algorithms: A Case Study On The Use Of Noninteger Slater-Type Orbitals, Ali̇ Bağci
Turkish Journal of Physics
This study presents an evaluation of derivative-free optimization algorithms for the direct minimization of Hartree−Fock−Roothaan energy functionals involving nonlinear orbital parameters and noninteger-order quantum numbers. The analysis focuses on atomic calculations employing noninteger Slater-type orbitals. Analytic derivatives of the energy functional are not readily available for these orbitals. Four methods are investigated under identical numerical conditions: Powell’s conjugate−direction method, the Nelder−Mead simplex algorithm, coordinate-based pattern search, and a model-based algorithm utilizing radial basis functions for surrogate-model construction. Performance analysis is first carried out using the Powell singular function, a well-established test case exhibiting challenging properties, including Hessian singularity at the …
Analytical Eigenmode Framework For Triplet-Mediated Fluorescence Dynamics Under Pulsed Excitation, Bariş Demi̇rbay
Analytical Eigenmode Framework For Triplet-Mediated Fluorescence Dynamics Under Pulsed Excitation, Bariş Demi̇rbay
Turkish Journal of Physics
An exact analytical solution to a three-state photophysical model is presented to explicitly map the time-resolved fluorescence dynamics of a fluorophore under pulsed excitation. As distinct from earlier analytical treatments that primarily focused on transient absorption and total ground-state depletion, the proposed eigenvalue-eigenvector framework captures both transient and steady-state emission responses. The photophysical model accounts for electronic transitions between the singlet ground state, the excited singlet state and a long-lived triplet state, enabling a treatment of excitation, radiative decay, intersystem crossing, together with triplet-state relaxation. By diagonalizing the rate matrix consisting of phenomenological transition rates, closed-form expressions for the time-dependent …
Coupling A Discrete State To A Quasi-Continuum: A Model Quantum-Mechanical System That Interpolates Between Rabi Oscillations And Decay-Revival Dynamics, Enes Kutay İşgörür, Osman Cevheroğlu, Arkadaş Özakin
Coupling A Discrete State To A Quasi-Continuum: A Model Quantum-Mechanical System That Interpolates Between Rabi Oscillations And Decay-Revival Dynamics, Enes Kutay İşgörür, Osman Cevheroğlu, Arkadaş Özakin
Turkish Journal of Physics
We formulate a quantum-mechanical system consisting of a single discrete state coupled to an infinite ladder of equally spaced states, with the coupling described by a Lorentzian profile. Various limiting cases of this system correspond to well-known models in quantum optics: the narrow-resonance limit yields the Rabi model, the wide-resonance limit yields the Bixon--Jortner model, the wide-resonance true continuum limit yields the Wigner--Weisskopf model, and the fixed-resonance true continuum limit yields a system typically studied using methods developed by Fano. We obtain a semianalytical solution to the eigenvalue problem by reducing it to a transcendental equation and demonstrate the limiting …
Local Integrals Generating Exact Integrals Of Motion In Three-Dimensional Potential Fields: Part I, Fazliddin Shamshiev
Local Integrals Generating Exact Integrals Of Motion In Three-Dimensional Potential Fields: Part I, Fazliddin Shamshiev
Turkish Journal of Physics
The problem of identifying additional local integrals of motion in generic three-dimensional potentials remains a fundamental issue in dynamical systems and galactic dynamics, since most realistic gravitational fields lack global symmetries or separable coordinate systems. In this study, we propose a general constructive method for deriving such local integrals by introducing auxiliary functions whose gradients define an orthogonal frame adapted to the potential. The central idea is that the velocity field can be characterized by two quadratic algebraic relations whose compatibility conditions uniquely determine the orthogonal frame and ensure the existence of two additional isolating integrals. Our main results include: …