Digital Commons Network^™

Transportation Barriers To Healthcare Access: A Scoping Review Of Measurement Approaches And Associated Health Outcomes, Josiane Kabayundo, Muskan Ahuja, Snehal Jadhav, Lisa C. Smith, Farzana A. Bithi, Shamim Shahi, George Johnson, Siddhi Munde, Kendra L. Ratnapradipa

Journal Articles: Epidemiology

Background

Objectives

Methods

Brain-Targeting Polymeric Micelles For Intranasal Delivery Of Rapamycin In Alzheimer’S Disease Treatment, Vrashabh V. Sugandhi

Theses and Dissertations

Alzheimer’s disease (AD) is a long-term neurological disorder associated with neuroinflammation and amyloid-beta (Aβ) aggregation, which leads to a decline in cognitive and behavioral changes. Rapamycin (Rapa) is an immunosuppressive drug effective in preventing organ rejection after a kidney transplant. In the last few years, orally delivered Rapa has emerged as a potential candidate for improving cognitive function in patients with AD. However, it is evident that long-term oral treatment of Rapa causes systemic toxicity, and although controversial, it may even trigger the aggregation of Aβ deposition. This study investigated the therapeutic potential of intranasally delivered brain-targeting polymeric micelles carrying …

State Plan On Aging, Tennessee. Department Of Disability And Aging

State Plan on Aging

This document includes plans to be conducted by the Tennessee Department of Disability and Aging under the provisions of the Older Americans Act from the period of October 1, 2025 through September 30, 2027.

2025-2026 Factbook, Tennessee. General Assembly

Factbook

This Fact Book provides an overview of the state's budget for the fiscal year.

Establishment And Characterization Of Vincristine-Resistant S1 Colon Cancer Cells, Harsh Patel

Theses and Dissertations

Colorectal cancer (CRC) remains one of the most common causes of cancer-related mortality worldwide. Vincristine is frequently used to treat CRC, although the specific pathways leading to acquired resistance are still not fully understood. In this study, we established two novel vincristine-resistant human colon cell lines (S1/V1 and S1/V4) to explore the mechanisms underlying vincristine resistance, with a particular emphasis on the overexpression of ATP-binding cassette (ABC) transporters. The S1/V1 and S1/V4 sublines were derived by continuously exposing human S1 colon cancer cells to vincristine. An MTT cytotoxicity assay revealed that S1/V1 cells exhibit about 39-fold greater resistance to vincristine …

Gastronomy At The Heart Of Communication: A Locus Of Human Conviviality, Victoria M. O’Keefe

Theses and Dissertations

The significance of food over time is central to humanity and can aid in making people humane in a myriad of ways. This study seeks to (a) define the role of food in communication across sectors of global society and in the media realm (b) by analyzing a data set of all food related publications of the flagship magazine of UNESCO, The Courier, (c) through ethnographic study and inductive coding, I draw themes and trends that alter food communication from a multinational organization and pass the content through a theoretical lens and Large Language Model tool, to (d) illuminate implications …

Expression And Function Of Floral Symmetry Genes In The Regulation Of Flower Shape In Fedia Graciliflora, Theresa A. Mustacchio

Theses and Dissertations

Shifts between radial symmetry (actinomorphy) and bilateral symmetry (zygomorphy) in flowers have occurred multiple times independently within angiosperms (flowering plants). Evidence across angiosperms indicate the transcription factors RADIALIS (RAD), DIVARICATA (DIV), and CYCLOIDEA (CYC) play a major role in regulating floral symmetry and morphology. The CYC-like genes have been shown to shift their expression dorsally independently in nearly all shifts to bilaterally symmetrical flowers examined. Three core eudicot clades of CYC-like genes have been identified: CYC1, CYC2 and CYC3, with only CYC2 genes being shown to have a role in floral symmetry. We use the non-model plant, Fedia graciliflora (Caprifoliaceae) …

Propelling Whole-Cell Biosensor Creation By Leveraging Gene Fusion To Assemble Synthetic Functional Transcription Factors For The Detection Of Biomarkers, Samuel J. Verzino

Theses and Dissertations

Biosensors are analytical devices that leverage biological modules for the detection of molecules of interest. As customizable tools designed to aid in a wide array of diagnostics, these instruments are rapidly advancing the field of synthetic biology. While varied in their construction and purpose, biosensors are ultimately concerned with converting a physicochemical stimulus into a detectable signal. Among the many existing variants, whole-cell biosensors (WCBs) stand out due to their versatility and engineering potential. WCBs are a type of biosensor in which a physiologically active cell sustains an array of biomolecular elements - receptors, transporters, regulators, etc. - capable of …

The Long Shadow Of Pride And Prejudice On Contemporary Fictions Of Arranged Marriage And Marriages Of Alliance, Candice Belluscio

Theses and Dissertations

This dissertation is an examination of the conflicts between arranged marriage and companionate marriage in selected contemporary Anglo-Indian novels and novels about Orthodox Judaism. The project’s guiding focus is how modern ideals of independence and choice in marriage coexist simultaneously with older ideals of marriage as family or personal “alliance.” The dissertation has a historical chapter that shows that although ideals of companionate marriage have become norms of 20th century western society and literature, the term “companionate marriage” is a recent invention and convention, and that various degrees and forms of arranged marriage, or marriages of alliance, continue despite their …

Latent Transition Analysis Of Prosocial Behavior And Physical Aggression In Toddlerhood, Annette Schieffelin

Theses and Dissertations

The current study is the first to apply Latent Transition Analysis (LTA) to examine short-term stability and change in toddlers’ physical aggression and prosocial behavior, using a person-centered, longitudinal approach to capture behavioral heterogeneity and stability during a critical developmental period. Mothers of 333 toddlers (18 or 24 months at Time 1; 21 or 27 months at Time 2) completed reports of provoked and unprovoked aggression, prosocial behaviors (helping, sharing, comforting), temperament, and parenting practices. Four profiles emerged consistently across time: High Aggression / Low Prosocial, Low Aggression / Average Prosocial, Low Aggression / High Prosocial, and Average Aggression / …

Sonic Futures: Exploring Podcasting, Artificial Intelligence, And The Evolving Landscape Of Composition, Grant David Crawford

Theses and Dissertations

This dissertation investigates podcasting and audio projects as multimodal practices in composition, analyzing how audio-based assignments both challenge and reproduce traditional writing norms. Drawing from personal teaching experience and a dataset of publicly accessible assignment prompts, rubrics, and instructional guides, the study examines how podcast projects are framed, assessed, and implemented in higher education. While often promoted as creative and accessible alternatives to essays, these assignments frequently replicate the same thesis-driven, rubric-centered, and exclusionary structures that define conventional academic writing. Through a cross-textual analysis of fifteen podcast rubrics and fifteen assignment prompts, this project identifies recurring patterns, including paradoxical expectations …

Embracing An Online Literary Identity: How Booktok Makes Literature More Accessible, Elizabeth Kaufmann

Theses and Dissertations

In this thesis I examine conversations that occur on TikTok’s literary corner, “BookTok.” My research involves focusing on the multimodality of BookTok, following comment sections and search options, as well as analyzing the components of the videos themselves. BookTok content creators focus on these features in order to spark literary conversation in an approachable way. These influencers heavily sway the app itself and the books being recommended. Extending my research beyond BookTok influencers, this essay seeks to understand the value of influencer backing on products towards their social legitimacy. Some users on TikTok are not fans of how the algorithm …

Predicting Price Movements Of The S&P 500 Using Conventional And Alternative Market Indicators, Patrick M. Scarborough

Theses and Dissertations

This thesis investigates whether integrating alternative data sources with conventional financial indicators enhances S&P 500 forecasting accuracy in modern financial markets characterized by increased complexity and rapid information flows. The study analyzes daily S&P 500 returns using twelve predictor variables comprising conventional indicators (VIX volatility index, WTI crude oil, gold futures, AAA bond yields, Federal Funds Rate, Treasury yield spreads) and alternative data sources (Bitcoin returns, Daily News Sentiment Index, Indeed job postings, Economic Policy Uncertainty Index) across 1,341 observations from February 2020 to June 2025. The methodology employs ordinary least squares regression and ARIMAX(5,5) modeling with rigorous preprocessing including …

“Makings Of A Teenage Revolutionary”: An Analysis Of Power Through The Lenses Of Gender And Institution Within The Universes Of Frank Herbert’S Dune And Suzanne Collins’ The Hunger Games, Ayah Cruzado

Theses and Dissertations

It is my objective within this paper to lead us through an in depth analysis of both Katniss Everdeen and Paul Atriedes, investigating every feature of their lives especially in the ways that they compare and differ to one another, after all, it is their written depth and complexity that makes them and their novels so fascinating to the public and earning them fame. Through my exploration, I hope to shed some light on the ways these three elements work and coincide with one another within both narratives. To separate them from one another and simply examine them as independent …

The Relationship Between Psychotherapist Self-Disclosure And Occupational And Emotional Variables, Kay Nikiforova

Theses and Dissertations

The effect of therapist self-disclosure practices on patients and the therapeutic relationship has long been debated. The historical trend of viewpoint toward self-disclosure began from predicting a negative, therapy-interfering stance to a growing openness towards the consideration that therapists sharing about themselves in session can have a positive effect on the patient. Evidence exists for both potential patient benefit and harm from therapists engaging in self-disclosure. Still, there is an increasing body of evidence that demonstrates that therapist self-disclosure benefits the therapeutic process, increases patient disclosure, and provides a more positive view of the therapeutic relationship. However, at present, there …

Analysis Of The Influence Of Telomere Length Variation On Flowering Time And Plant Fitness In Arabidopsis, Brianna Spadavecchia

Theses, Dissertations and Capstones

Telomeres are conserved structures at the ends of eukaryotic chromosomes that promote genome stability. In most eukaryotes, the DNA found within these protective end caps consists of short, G-rich nucleotide repeats. Cells with critically short telomeres face a variety of potential adverse outcomes such as end-to-end chromosome fusion, apoptosis, etc. The length of telomeric DNA varies substantially between different plant species and even between genotypes of the same species. A previous study using T-DNA mutants of the model plant Arabidopsis thaliana with long or short telomeres suggested that telomere length may be an adaptive trait. Specifically, for reproductive fitness, the …

Raising Cybersecurity Awareness In Central Florida Communities, Jacob S. Freeman

High Impact Practices Student Showcase Fall 2025

The threat of cyberattacks is larger than ever. As our lives move further into the digital age, attackers become smarter, learn new techniques, and exploit subtler vulnerabilities. If we want to train a generation that is protected from these threats, it is our responsibility to start educating people early, not just after they enter the workforce.

To do this, I partnered with a non-profit student organization called the Collegiate Cyber Defense Club, better known as Hack@UCF, to teach the UCF student body and others in the Central Florida area about cybersecurity. Our focus was on both understanding modern threats and …

Winter 2025, Augustana College, Rock Island Illinois

Augustana Magazine

No abstract provided.

Species-Specific Discrimination Of Bacterial Biofilms Using A Ratiometric Fluorescence Sensor Array And Machine Learning, Ritika Gupta, Aayushi Laliwala, Elena Muldiiarova, Kenneth W. Bayles, Denis Svechkarev, Marat Sadykov, Aaron M. Mohs

Journal Articles: Pathology and Microbiology

Biofilms are intricate bacterial communities encased in a self-produced extracellular matrix (ECM) of DNA, lipids, proteins, and polysaccharides. The diverse ECM composition across bacterial species significantly influences the progression of biofilm-associated infections, making precise identification crucial for effective treatment. Traditional methods such as biochemical assays, MALDI-TOF mass spectrometry, DNA sequencing and culturing provide valuable insights but have notable drawbacks, including time-consuming procedures, high costs, and the need for specialized equipment and trained personnel. These limitations hinder the rapid and widespread adoption of biofilm identification in clinical settings, underscoring the need for more streamlined, accurate, and accessible methods. In this study, …

Where Do The 4winds Blow?: Developing 4winds Map, A Geocritical Vgi Application, Andy Trinh

Theses & ETDs

Crowdsourced neogeography and Volunteered Geographic Information (VGI) applications have become popular in the realm of data aggregation, crisis management, and public policy advocacy, but its use for narrative storymapping is only now steadily increasing. New College, which has always had a complicated history, is in a unique period for alumni to share the impact New College has had on their life with other generations of alumni. 4Winds Map provides a storymapping platform to share stories in an archival and accessible manner. Research regarding design practices of data-based VGI applications is readily available, but methodology considerations of community storymapping VGI applications …

The Queen’S Gambit, Jennifer Stegman

Theses & ETDs

The Queen’s Gambit by Walter Tevis is both a novel and a Netflix mini series about a female chess prodigy, Beth Harmon, navigating the world of chess in the mid-twentieth century. The adaptation to screen in 2020 sparked a global interest in chess, especially among women. My thesis analyzes the adaptation from novel to series, the use of music as a narrative tool, the historical context, the chess games themselves, and the character development. I will be integrating my personal experience as a female chess player, and focusing on how my evolution and experience as a player mirrors Beth’s. I …

Applications Of Marine Optics: Satellite-Derived Bathymetry, Light Attenuation Measurements Via Multi-Spectral Light Sensors, And Colored Dissolved Organic Matter Spectral Analysis, Noah Tyler

Theses & ETDs

This thesis aims to explore three applications of the field of marine optics. First, some marine optical principles are applied to satellite imagery to generate satellite-derived bathymetry (SDB) charts for Sarasota Bay, FL. SDB charts were successfully created using satellite images from July and August of 2023. Unique terrain features, such as the intercoastal waterway, can be seen in the SDB charts. Next, a multi-spectral light sensor system (MSLSs) was developed so it could be utilized to measure attenuation as a proxy for turbidity using marine optics concepts. The MSLSs were deployed in Sarasota Bay to collect attenuation data. The …

A Life In Documents: A Case Study In Building Information Literacy Skills Through The Processing And Creation Of A Finding Aid For The Helen Fagin Archive Collection At The Jane Bancroft Cook Library, Fiona White

Theses & ETDs

This thesis covers the work done during the Dr. Helen Fagin Archival Internship Project while reflecting on the interaction of the project with information literacy skills, and how it can serve as an exercise in building said skills. The internship itself focuses on the processing of the personal collection donated to the Jane Bancroft Library by Dr. Fagin, with the primary goals being to complete the physical processing of the collection, thereby appraising, arranging, and preserving the collection, and endeavoring to work its amplification, raising awareness of and accessibility to the collection. A synthesis of these two objectives is embodied …

Practicing Intercultural Discipleship, Akali Nya

Academic Books

No abstract provided.

Annual Report: Fy 2025 Quality Of Kerosene And Motor Fuel In Tennessee, Tennessee. Department Of Agriculture

Annual Reports on Kerosene & Motor Fuel Quality

The annual report provides data on the effectiveness of the 1989 Kerosene and Motor Fuels Quality Inspection Act, consumer complaints, inspection data, and summary of enforcement.

Calling Lawyers In, Instead Of Out: The Role Of The Conscious Lawyer, Siwatu-Salama Ra

JCLC Online

No abstract provided.

From Oppenheimer To Trump: An Exploration Of The American History Of Prosecution And Persecution In Classified Information Dissemination, Samuel Bevenour

JCLC Online

Robert Oppenheimer, the father of the atomic bomb, was stripped of his security clearance before documents were properly classified and without access to exculpatory evidence in what amounted to a show trial. The modern, peace-time classification system has expanded into an arguably uncontrollable leviathan that has proven unable to be curtailed by either political party despite bipartisan support. The usage of the related Espionage Act to enforce the ever-growing secrecy state has a problematic history of being utilized in politically motivated prosecutions in which defendants still face an uphill battle to gain access to exculpatory information. These prosecutions, under the …

Stopping The Spread Of The World's Oldest Hatred - What U.S. Sports Stakeholders Can Do To Combat Antisemitism, Mark Conrad

Fordham Intellectual Property, Media and Entertainment Law Journal

The consistent rise in reported acts of antisemitism in the United States over the last decade has prompted debate about strategies to combat this age-old menace. The Hamas attack on Israel and the subsequent Israeli military response in Gaza has exacerbated this trend. Many have debated ways to confront the issue, including informing the public about the magnitude of the problem and finding policies to reduce incidents of antisemitism. The sports industry could help in this quest. Because millions of people follow professional, college, high school, and Olympic sports, organizations and individual athletes could participate in activities designed …

Public Support For War And Desertion, Joshua Delaigle

Sigma: Journal of Political and International Studies

Since the beginning of war, soldier desertion has been an issue for military leaders and the politicians supporting them. Desertion from the United States Military is defined in Title 10 of the U.S. Code Article 85 as a member of the armed forces who goes or remains absent from his or her unit or place of duty with the intent to remain away permanently (“10 U.S. Code § 885”). Desertions lessen both unit cohesion and combat readiness, potentially changing the tide of a war. For these reasons, military leaders and academic researchers have been concerned with understanding the phenomenon of …

Ram-Amazing Care: Making Mental Health A Priority, Together, Matthew Pawlowicz, Chelsea Gary, Sara Barton, Matthew Majid

The Grace E. Harris Leadership Institute Publications

Maintaining student mental health is a significant and growing challenge for universities. Difficulties with mental health decrease students’ overall well-being and can contribute to students performing poorly in classes, entering academic probation, and failing to complete their degree on time, or at all, among other negative consequences for the university community generally. To help meet the need for mental health care, VCU partnered with TimelyCare in 2020 to provide a variety of online mental health care resources. The partnership has enrolled more than 3,000 student users, though that is less than 15% of the student population. And so, our project …