Digital Commons Network^™

Bridging Policy And Grassroots Action With Technology: A Framework For Civic Engagement In Environmental Sustainability, Mikhail Ola Adisa, Sonny Rosenthal, Shola Oyedeji, Ifeoma Adaji, Jari Porras

Research Collection College of Integrative Studies

Grassroots and civic organizations are increasingly recognized as “middle actors” in sustainability, leveraging ICT-driven solutions to bridge top-down policies with bottom-up citizen engagement and behavioral change. This study examines how civic organizations in Finland and Singapore integrate digital tools to support sustainable waste management practices aligned with Sustainable Development Goals 11, 12, and 17. Guided by a Design Science Research (DSR) approach and drawing on Middle-Out and multi-level governance theories, we developed and validated the Integrated Sustainability Engagement Framework (ISEF) based on interviews with 21 civic organizations and iterative feedback. Findings highlight the central roles of policy translation, localized practices, …

A Hydrogen Hub Blueprint For The California Supply Chain, Tyler Reeb, Barbara Taylor

Mineta Transportation Institute

As global climate targets tighten and state regulations accelerate, hydrogen technology presents a significant opportunity to help California supply chain and transportation stakeholders comply with state emissions mandates and global goals aimed to reduce the impacts of climate change. However, while fuel cell costs and infrastructure have received attention, workforce development remains overlooked. Hydrogen fuel cell electric vehicles (FCEVs) are especially promising for diesel-reliant sectors that are hard to decarbonize without negatively impacting operational efficiency. But scaling hydrogen vehicles and infrastructure in tandem with emerging consumer and industrial markets will not be easy. State and federal policies, often conflicting, further …

2026 February, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for February of 2026.

The Feelit System: Application Content-Aware Perspectives And Challenges On Understanding User Likes In Social Network Posts, Konstantinos Theocharidis, Hady W. Lauw, Panagiotis Karras

Research Collection School Of Computing and Information Systems

In a series of our prior works, we study influence and subscription maximization problems in social networks that are based on posts having influential content; as content we consider a set of features where each feature corresponds to a specific social network page, whereas influence and subscription relate to gaining the postlike and subscription-to-brand page of targeted users, respectively; subscription is conceptually achieved as repetitive influence on users. So, both influence and subscription depend on content that gains the likes of users; however, to be realistic, modeling and estimating such likes is a complex problem that has not been adequately …

Study Of Nano-Bio Interactions In Biological Fluids: Modelling And Simulations., Beatrice Cipriani

Doctoral

Nanoparticles have attracted significant interest due to their tunable properties and unique physicochemical characteristics, offering promising applications in drug delivery, biosensing, and diagnostics. Their use in medicine has the potential to reshape current paradigms by enabling more efficient, precise, and patient-centric approaches. Although advances in nanomaterial synthesis have rapidly expanded the library of available nanodevices, our understanding of the mechanisms that govern their behaviour at biological interfaces remains limited. Nanoparticles are similar in size to biomolecules found in biological environments, leading to complex, competitive interactions that affect their functional performance, biological fate, and acquired bioidentity. Unlike traditional small molecules, which …

Counter-Urbanization In China: A Systematic Review Toward A Comprehensive Typology, Chengxue Yang, Qian Forrest Zhang

Research Collection School of Social Sciences

Drawing on a systematic review of both international and Chinese-language scholarship on counter-urbanization in China, this article proposes a comprehensive typology of counter-urbanization migrations—consisting of eight types of new migrants—based on the diverse motivations driving such migration. We build a bilingual corpus of 273 research papers published between the 1970s and 2025. Integrating bibliometric mapping and qualitative synthesis, we conduct a systematic review to trace the temporal evolution and thematic diversification of counter-urbanization research. The review reveals persistent conceptual ambiguity surrounding counter-urbanization in the Chinese context, which this study addresses by conceptually distinguishing counter-urbanization from suburban expansion, population decentralization, and …

The Affective Economy Of Toxic Atmospheres: Sensory Governance, Ecological Intelligences And The Performative Politics Of Urban Mosquito Management, Orlando Woods, Creighton Connolly

Research Collection College of Integrative Studies

This paper considers how atmospheres can play a powerful role in troubling the management of nature in the multispecies city. It brings the cyclical nature of atmospheric effects, the affective values and il/logics that determine human responses to non-human threats, and the misguided and potentially deleterious health outcomes that ensue into one analytical frame. Drawing on the empirical case of urban mosquito management in Singapore, it considers how the creation of toxic atmospheres through fogging – blowing insecticides into the air in a bid to kill mosquitoes – is ineffective and sets in motion a cascading series of socio-environmental consequences. …

Geopolitical Ecologies Of Cloud Capitalism: Territorial Restructuring And The Making Of National Computing Power In The Us And China, Justin Kollar, Sol Andrew Stokols

Research Collection College of Integrative Studies

As computing power becomes central to geopolitical rivalry, cloud infrastructure is increasingly framed as critical to national security, economic resilience and technological sovereignty. Current debates often focus on global competition – especially between the U.S. and China – highlighting strategic investments, export controls and infrastructure diplomacy abroad. Yet far less attention has been paid to the domestic territorial transformations that make such geopolitical projection possible. This paper argues that national strategies for AI and cloud dominance depend on the reorganization of land, energy and regulatory systems to sustain large-scale computation. Using a geopolitical ecology framework, we examine how the U.S. …

Review Of China’S New Youth: How The Young Generation Is Shaping China’S Future, Douglas Iwama

Armstrong Undergraduate Journal of History

No abstract provided.

Loss Of Beta-Cell Identity And Function As A Mechanism Of Secondary Failure Of Sulfonylurea Therapy In Diabetes, Sumit Patel, Zihan Yan, Maria S Remedi

2020-Current year OA Pubs

Sulfonylureas, commonly used to treat type 2 diabetes (T2D), often lose effectiveness over time when used as monotherapy; however, the underlying mechanisms remain unclear. To investigate the mechanisms of sulfonylurea failure, glibenclamide-releasing pellets were implanted in KK mice, a polygenic model that spontaneously develops T2D. KK mice receiving placebo pellets (KK-Placebo) developed hyperglycemia, hyperinsulinemia, glucose intolerance, and insulin resistance. Notably, KK mice implanted with glibenclamide (KK-Glib) showed improved blood glucose levels during the first 7 days, returning to KK-Placebo levels thereafter. KK-Glib mice exhibited reduced plasma insulin levels and insulin secretion in response to a glucose challenge compared with the …

Investigating The Oxygen Dependence Of Flash-Rt Using Electron Paramagnetic Resonance Imaging, Trey Waldrop, Grace Murley, Brett Velasquez, Elise Konradsson, Denae Neill, Luke Connell, Alan Lopez Hernandez, Abagail Delahoussaye, F William Schuler, Jorge De La Cerda, Ziyi Li, Mark D Pagel, Emil Schüler

Faculty, Staff and Student Publications

Purpose: The FLASH effect occurs when radiation given at ultra-high dose rates spares healthy tissue while achieving isoeffective tumor control relative to conventional (CONV) dose rate irradiation. Limited data has implicated oxygen in the FLASH effect. This study investigated the effect of tissue oxygen tension (pO2) on gastrointestinal (GI) FLASH sparing in mice.

Methods: pO2 was quantified in vivo by electron paramagnetic resonance imaging (EPRI)- noninvasive oximetry through spin probe injection and magnetic resonance co-registration- and a phosphorescent quenching microsensor. B6(Cg)-Tyrc-2 J/J female mice were imaged while breathing 10%, 21%, and 95% oxygen. C57BL/6 mice of both sexes underwent microsensor …

Design And Implementation Of An Aapm Volunteer Database For Advancing Global Medical Physics Initiatives., Teh Lin, Minsun Kim, Courtney Morrison, Jiahan Zhang, Kevin Little, Yan-Hong Xin, Michael Woodward, Peter Sandwall, Eun Young Han

Oncology Articles

PURPOSE: The purpose of this study is to assess American Association of Physicists in Medicine (AAPM) members' availability to volunteer, share their expertise, and promote global collaboration in medical physics by partnering with international colleagues who seek support in strengthening their medical physics practice.

METHODS: The questionnaire was administered to AAPM members to assess their willingness to volunteer, preferred engagement modalities, and availability for different types of volunteer activities. The questionnaire was integrated into the AAPM member profile and covered therapy, diagnostic, and nuclear medicine disciplines, capturing participants' visiting preferences and expertise in teaching and training. Respondents were categorized based …

The Case For An African Investment Court (Aic), Won L. Kidane

Faculty Publications

No abstract provided.

Cultural Influences On Camouflaging And Autistic Burnout: Examining The Experiences Of Latino Autistic Young Adults, Antonio F Pagán, Katherine A Loveland, Ron Acierno

Faculty, Staff and Student Publications

The present study explored the relationship between camouflaging, autistic burnout, and cultural factors in Latino young adults with autism spectrum disorder (ASD). While autistic burnout and camouflaging have been widely studied in general ASD populations, limited research has focused on Latino individuals, who may experience unique pressures due to cultural values such as collectivism, familism, and traditional gender roles. Participants (N = 56) from the ¡Iniciando! la Adultez therapy program completed measures assessing burnout, camouflaging, acculturation, and cultural values. Results indicate that participants reported moderate to high levels of autistic burnout, with the highest levels observed in heightened self-awareness …

Novel Small-Molecule Analogues Of Iu1 Ameliorate Amyloid-Β Mediated Toxicity In Alzheimer’S Disease Cell And Worm Models, Ajish Ariyath, Fraulein Denise Arigo, Izhar Wallach, W. M.A.D.Binosha Fernando, Ralph N. Martins, Prashant Bharadwaj

Research outputs 2022 to 2026

Dysregulation of the deubiquitinating enzyme Ubiquitin-specific peptidase 14 (USP14) is implicated in several neurodegenerative diseases, and IU1, an allosteric inhibitor, has shown neuroprotective effects by reducing protein aggregate toxicity. This study aimed to develop new IU1 analogues and evaluate their ability to mitigate amyloid-β (Aβ) accumulation and toxicity in Alzheimer’s disease (AD) cell and Caenorhabditis elegans worm models. IU1 and 71 newly designed analogues identified using the AtomNet^® virtual screening platform were assessed in an amyloid precursor protein-C terminal fragment/amyloid-β (APP-C99/Aβ)-producing AD cell model using a high-throughput toxicity assay. Lead compounds were further evaluated for their effects on neurodegeneration, …

Acute Otitis Media: Antibiotic Length, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Diagnostic Limitations, Patient Characteristics, And Confounding Factors Impacting Neurotologic Lesion Imaging: A Systematic Review, Diana Hamdan, Precious Ochuwa Imokhai, Alexandra Konvalina, Baokhanh Nguyen, Maha Alhoda, Valentina Alejandra Da Silva Acosta, Waseem Syed, Amanda Brooks

Student Publications

Background: Neuroimaging protocols for neurotologic disease are often developed without consideration of patient-specific factors such as biological differences, clinical presentation variability, and comorbidities. This lack of tailored design contributes to insufficient detection, delayed diagnosis, and inappropriate treatment. Objectives: To critically examine the literature on diagnostic limitations of neuroimaging for neurotologic lesions and identify gaps in protocol validation, accuracy, and clinical translation. Methods: A systematic review of PubMed and Google Scholar was conducted, focusing on studies published between 2015 and 2025 that evaluated diagnostic imaging outcomes in patients with neurotologic lesions. Eligible studies included prospective cohorts, retrospective analyses, …

A Comparative Study Of Word Embedding Techniques For Classification Of Star Ratings, Craig Mcneile, Malgorzata Wojtys, Hesham Abdelmotaleb

School of Engineering, Computing and Mathematics

Telecom services are at the core of today’s societies’ everyday needs. The availability of numerous online forums and discussion platforms enables telecom providers to improve their services by exploring the views of their customers to learn about common problems that customers face. Natural Language Processing (NLP) tools can be used to process the free text collected.One way of working with such data is to represent text as numerical vectors using one of many word embedding models based on neural networks. This research uses a novel dataset of telecom customers’ reviews to perform an extensive comparative study showing how different word …

Digital Marine Citizenship Toolkit: Connecting To The Sea – The Role Of Digital Engagement For Marine Citizenship, Katharine Willis, Kizzy Beaumont

School of Art, Design and Architecture

Digital Marine Citizenship (DMC) uses creative and digital tools, often developed through artistic and creative practice, to help people connect with, care for, and takeaction for their local seas. It offers practical ways to understand our relationship withthe ocean and to play an active role in shaping sustainable coastal futures.By combining creativity and technology, and working with artists and communitiesto design meaningful experiences, DMC helps turn awareness into action and fosters a shared sense of belonging to the marine environment.This Toolkit has been created to inspire and support practitioners, community groups, and organisations who want to explore digital and creative …

Back-On-Track: Protocol For Randomised Controlled Feasibility Trial Of Behavioural Activation In Farmers With Mood Problems, Alison Kennedy, Richard Gray, Martin Jones, Anna Greene, Lauren Mitchell, Meera Senthuren, Suzy Malseed, Feby Savira, Kelly Barnes, Kate Gunn, Susan Brumby

Research outputs 2022 to 2026

The mental health of people living in farming communities has been identified as an important public health issue. Cumulative exposure to a range of situational factors contributes to heightened risk of poor mental health and suicide. Access to evidence-based psychological treatments is limited by the availability of skilled mental health professionals. The aim of this trial—co-designed by members of the farming community—is to establish the feasibility of conducting randomised controlled, trial-testing, peer-worker-delivered Behavioural Activation in the farming community. We will undertake a single-blind, parallel group, randomised controlled feasibility trial in rural Australia. People living in farming communities aged over 15 …

Navigating Climate Change In Carbon Negative Bhutan: Insights From Policy Influencers And Comparison To The Wider Himalayan Region, Tashi Dorji, Angus Morrison-Saunders, David Blake

Research outputs 2022 to 2026

Climate change is one of the most pressing global challenges and spares no nation. Bhutan, as the only carbon negative country in the world, is no exception and being in the Himalayas – a region warming faster than the global average – further intensifies climate risks. This study explores how Bhutan navigates climate change through the perspectives of 41 policy influencers, including politicians, civil servants, and leaders from nongovernment organisations and the media. The findings are compared with scientific literature from the broader Himalayan region to identify shared vulnerabilities (e.g., glacial lake outburst floods, water scarcity, and agricultural disruptions) and …

Prisrv+: Privacy And Usability-Enhanced Wireless Service Discovery With Fast And Expressive Matchmaking Encryption, Yang Yang, Guomin Yang, Yingjiu Li, Pengfei Wu, Rui Shi, Minming Huang, Jian Weng, Hwee Hwa Pang, Deng, Robert H.

Research Collection School Of Computing and Information Systems

The evolution of decentralized identity (DID) and self-sovereign identity (SSI) frameworks, as endorsed by W3C Verifiable Credentials (VC) and eIDAS 2.0, underscores the need for secure, efficient, and privacy-preserving credential management. However, existing credential systems often depend on centralized issuers, lack efficient aggregation mechanisms, or fail to ensure unlinkability across authentication sessions. To address these challenges, we propose DISC (Decentralized Identity System with Self-Sovereign Credential Aggregation), a novel credential system that enables multi-authority credential issuance, user-controlled credential aggregation, and unlinkable authentication. DISC allows users to aggregate credentials from multiple issuers while maintaining constant-size authentication tokens and supporting batch verification for …

Ubiquitination Of Oncogenic Mutant P53 Via Attenuation Of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth, Mudassier Ahmad, Sahir Sultan Alvi, Haider Ahsan, Carlos Perez, Vivek Kashyap, Neeraj Chauhan, Dae Joon Kim, Nirakar Sahoo, Tamer Oraby, Murali Yallapu, Subhash Chuahan, Bilal Hafeez

School of Medicine Publications

Dysregulated ribosome biogenesis and p53 mutations are known to play oncogenic roles in various cancers, including pancreatic cancer. In this study, we demonstrated the therapeutic potential of BMH-21, a pharmacologic inhibitor of RNA polymerase I, against pancreatic cancer by uncovering a novel molecular mechanism involving RPA194-mediated ubiquitination of mutant p53 without affecting the ubiquitination of wild-type p53. Our key findings are that (i) BMH-21 selectively induces apoptosis and cell growth inhibition of pancreatic cancer cells with no effect on normal human pancreatic ductal epithelial cells; (ii) BMH-21 degrades RPA194; (iii) BMH-21 inhibits recruitment of both RPA194 and RPA135 on rDNA …

Overcoming Barriers To Hpv Vaccination In Pakistan: A Critical Need For A Proactive And Culturally-Sensitive Strategy, Syed Ahtisham Halim, Tirath Patel, Syeda Ramish Zehra Kazmi, Momina Khabir, Nikhilesh Anand

School of Medicine Publications

Cervical cancer continues to be one of the major causes of cancer-related mortalities among women worldwide, with a considerable share of this burden affecting developing countries like Pakistan. The addition of the HPV vaccine to the national immunization program of Pakistan had been a crucial leap toward the prevention of cervical cancer. Nevertheless, challenges that threaten the success of such a program are conspicuous. The most important ones are discussed in the letter, including the widespread dissemination of misinformation via social media on unfounded grounds, such as infertility resulting from the vaccine; deep-seated cultural taboos relating to sexual health; and …

Priority Without Progress: The Fda's Neglected Tropical Disease Voucher Program After 18 Years, Maple Goh, Kevin Outterson, Aaron Kesselheim

Faculty Scholarship

Introduction: To incentivize drug and vaccine development for neglected tropical diseases (NTDs), US Congress created the Priority Review Voucher (PRV) program in 2007. Sponsors that obtain Food and Drug Administration (FDA) approval for an eligible product receive a voucher redeemable to accelerate review of another product.

Methods: We reviewed the program’s public health impact by examining all 14 vouchers awarded for NTD products between 2007 and 2024, including the timing of FDA approval relative to World Health Organization (WHO) Prequalification, Essential Medicines List inclusion, first use in endemic countries, and voucher disposition.

Results: Eight (57%) achieved WHO …

The Case For Ai Authorship In Copyright Law, Cheng Lim Saw, Duncan Lim

Research Collection Yong Pung How School Of Law

Today, with generative AI, literary and artistic works can be created almost effortlessly. There is at present intense debate as to whether works generated by AI – broadly categorised as “AI-assisted” and “AI-generated” works – ought to attract copyright protection. AI-assisted works are those that involve some degree of human intervention. Where AI-generated works are concerned, however, such works are created autonomously by the AI itself with minimal (de minimis) input from an identifiable human being. Presently, it is generally accepted that AI-generated works do not attract copyright protection for want of a human author. This article examines whether it …

Cleavage And Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion And Hypoxic Response, Scott D Collum, Lisha Zhu, Tingting W Mills, Rene Girard, Jamie Tran, Tinne C J Mertens, Cory Wilson, Nancy Wareing, Erik E Suarez, Howard J Huang, Rahat Hussain, Bindu Akkanti, Wenjin J Zheng, Hari K Yalamanchili, Bela Patel, Eric J Wagner, Sandeep Agarwal, Harry Karmouty-Quintana

Faculty, Staff and Student Publications

Pulmonary hypertension (PH) is a fatal condition that affects individuals with systemic sclerosis (SSc), a multiorgan fibrotic disease with limited treatment options. A central feature of PH is vascular remodeling, defined by the narrowing of the arteriole lumen due to cell proliferation and extracellular matrix deposition. Herein, we identify a central mechanism that can regulate multiple transcripts important for vascular remodeling. The highlight of our study is the demonstration that reduced pulmonary artery smooth muscle (PASMC) Nudt21, which codes for the RNA binding protein Cleavage and Polyadenylation Specificity Factor Subunit 5 (CPSF5) The, known to regulate alternative polyadenylation, results …

"We're Going To Tear Up The Caldera So We Can Have An Electric Car": Wrestling With Prospective Lithium Mining In The Oregon Desert, Elizabeth Bartholomew, Alida Cantor, Kate Berry, Noel Vineyard

Geography Faculty Publications and Presentations

Extraction of lithium, a key ingredient for renewable energy transitions, is a land- and water-intensive process. In this study, we use qualitative, place-based research to explore socio-environmental imaginaries surrounding a landscape on the verge of change due to lithium mining. We examine the ways that different actors are wrestling with the costs, benefits, and uncertainties of potential open-pit lithium mining in Oregon’s section of the McDermitt Caldera. In contrast to previous research which has described support for mining amongst those closest to the mine site, we find that in this case, perceptions of mining are characterized by ambivalence, uncertainty, and …

Topple Headfirst Into The Dark: Restorative Justice In Missouri And Hope For The Future, Emma Donaldson

Journal of Dispute Resolution

Imagine you are not reading this article. Instead, you are walking back home from dinner with your friends. As you walk down the street, someone comes up behind you and demands you hand them your money. You turn around to give them all the money you have, only to lock eyes with the barrel of a gun. What are you feeling in this moment? A little bit of rage perhaps. Maybe your hands have started shaking. Or, just maybe, you are feeling a little defiant. But before you can even react, a police officer is running down the street, yelling …

Resolving Ranks: The Role Of Adr In Military Justice, Dane Puckett

Journal of Dispute Resolution

The United States (U.S.) Armed Forces is composed of seven military branches: Army, Navy, Air Force, Marine Corps, Coast Guard, National Guard, and Space Force. Each military branch has an alternative dispute resolution (“ADR”) program. These programs use a collection of techniques, generally informal and collaborative in nature, to resolve disputes as a substitute for litigation. The characteristics of ADR proceedings tend to produce quicker, less expensive outcomes compared to litigation. This very reason is why Congress enacted the Administrative Dispute Resolution Act (“ADRA”) of 1996, directing federal agencies to establish ADR policies and programs.