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Illinois State University Annuitants Association Newsletter, Summer 2022, Illinois State University, Annuitants Association

ISUAA News

Illinois State University Annuitants Association newsletter

Strategy In An Uncertain Domain: Threat And Response In Cyberspace, Joe Devanny, Luiz Rogerio Franco Goldoni, Breno Pauli Medeiros

Journal of Strategic Security

Over the last decade, "cyber power" has become an increasingly prominent concept and instrument of national strategy. This article explores the nature of contemporary cyber power, focusing on how states should respond to "cyber uncertainty." Cases of cyber operations against Estonia, Georgia, and Ukraine, as well as cyber operations conducted (and suffered) by the United States, highlight the evolving role of cyber operations as an instrument of statecraft. Given the complexity of cyber forensics and the polluted information environment of the global public sphere, the public diplomacy of coordinated attribution statements cannot be expected to cut through conclusively or uniformly. …

Drug Wars And Covert Netherworlds: The Transformation Of Mexico’S Narco Cartels. By James H. Creechan. Tucson: The University Of Arizona Press, 2021., Sabrina S. Laroussi

Journal of Strategic Security

No abstract provided.

Scientist's Warning On Climate Change And Insects, Jeffrey A. Harvey, Kévin Tougeron, Rieta Gols, Robin Heinen, Mariana Abarca, Et Al

Biological Sciences: Faculty Publications

Climate warming is considered to be among the most serious of anthropogenic stresses to the environment, because it not only has direct effects on biodiversity, but it also exacerbates the harmful effects of other human-mediate threats. The associated consequences are potentially severe, particularly in terms of threats to species preservation, as well as in the preservation of an array of ecosystem services provided by biodiversity. Among the most affected groups of animals are insects—central components of many ecosystems—for which climate change has pervasive effects from individuals to communities. In this contribution to the scientists’ warning series, we summarize the effect …

Identification And Quantitation Of Aqueous Single- And Multianalyte Solutions Of The Isomers Ethylbenzene, M-, P-, And O-Xylene Using A Single Specifically Tailored Sensor Coating And Estimation Theory-Based Signal Processing, Nicholas Post, Florian Bender, Fabien Josse, Edwin E. Yaz, Antonio J. Ricco

Electrical and Computer Engineering Faculty Research and Publications

The isomer-specific detection and quantitation of m-, p-, and o-xylene and ethylbenzene, dissolved singly and as mixtures in aqueous solutions at concentrations from 100 to 1200 ppb by volume, is reported for a specifically designed polymer-plasticizer coating on a shear-horizontal surface acoustic wave (SH-SAW) device. The polystyrene-ditridecyl phthalate-blend coating was designed utilizing Hansen solubility parameters and considering the dipole moment and polarizability of the analytical targets and coating components to optimize the affinity of the sensor coating for the four chemical isomers. The two key coating sorption properties, sensitivity and response time constant, are determined by the …

Openline Newsletter, July/August 2022, Civil Service Council

OpenLine Newsletter

A monthly newsletter for Civil Service employees, July/August 2022.

Addressing Futility: A Practical Approach, Piroska K. Kopar, Adrienne Visani, Kyler Squirrell, Douglas E. Brown

2020-Current year OA Pubs

UNLABELLED: Limiting or withdrawing nonbeneficial medical care is considered ethically responsible throughout most of critical care and medical ethics literature. Practically, however, setting limits to treatment is often challenging. We review the literature to identify best practices for using the definition of futility as an anchoring concept to aid the ethical practice of ICU clinicians.

DATA SOURCES: Source data were obtained from a PubMed literature review.

STUDY SELECTION: English language articles were chosen based on relevance to medical futility ethics, end-of-life care in the ICU, or communication and conflict mitigation strategies.

DATA EXTRACTION: Independent evaluation of selected articles for recurrent …

Onasemnogene Abeparvovec For Presymptomatic Infants With Two Copies Of Smn2 At Risk For Spinal Muscular Atrophy Type 1: The Phase Iii Spr1nt Trial, Kevin A Strauss, Craig M Zaidman, Et Al

2020-Current year OA Pubs

SPR1NT ( NCT03505099 ) was a Phase III, multicenter, single-arm study to investigate the efficacy and safety of onasemnogene abeparvovec for presymptomatic children with biallelic SMN1 mutations treated at ≤6 weeks of life. Here, we report final results for 14 children with two copies of SMN2, expected to develop spinal muscular atrophy (SMA) type 1. Efficacy was compared with a matched Pediatric Neuromuscular Clinical Research natural-history cohort (n = 23). All 14 enrolled infants sat independently for ≥30 seconds at any visit ≤18 months (Bayley-III item #26; P < 0.001; 11 within the normal developmental window). All survived without permanent ventilation at 14 months as per protocol; 13 maintained body weight (≥3rd WHO percentile) through 18 months. No child used nutritional or respiratory support. No serious adverse events were considered related to treatment by the investigator. Onasemnogene abeparvovec was effective and well-tolerated for children expected to develop SMA type 1, highlighting the urgency for universal newborn screening.

Onasemnogene Abeparvovec For Presymptomatic Infants With Three Copies Of Smn2 At Risk For Spinal Muscular Atrophy: The Phase Iii Spr1nt Trial, Kevin A Strauss, Craig M Zaidman, Et Al

2020-Current year OA Pubs

Most children with biallelic SMN1 deletions and three SMN2 copies develop spinal muscular atrophy (SMA) type 2. SPR1NT ( NCT03505099 ), a Phase III, multicenter, single-arm trial, investigated the efficacy and safety of onasemnogene abeparvovec for presymptomatic children with biallelic SMN1 mutations treated within six postnatal weeks. Of 15 children with three SMN2 copies treated before symptom onset, all stood independently before 24 months (P < 0.0001; 14 within normal developmental window), and 14 walked independently (P < 0.0001; 11 within normal developmental window). All survived without permanent ventilation at 14 months; ten (67%) maintained body weight (≥3rd WHO percentile) without feeding support through 24 months; and none required nutritional or respiratory support. No serious adverse events were considered treatment-related by the investigator. Onasemnogene abeparvovec was effective and well-tolerated for presymptomatic infants at risk of SMA type 2, underscoring the urgency of early identification and intervention.

Caspase-1-Driven Neutrophil Pyroptosis And Its Role In Host Susceptibility To Pseudomonas Aeruginosa, Karin Santoni, Christine T. N. Pham, Et Al

2020-Current year OA Pubs

Multiple regulated neutrophil cell death programs contribute to host defense against infections. However, despite expressing all necessary inflammasome components, neutrophils are thought to be generally defective in Caspase-1-dependent pyroptosis. By screening different bacterial species, we found that several Pseudomonas aeruginosa (P. aeruginosa) strains trigger Caspase-1-dependent pyroptosis in human and murine neutrophils. Notably, deletion of Exotoxins U or S in P. aeruginosa enhanced neutrophil death to Caspase-1-dependent pyroptosis, suggesting that these exotoxins interfere with this pathway. Mechanistically, P. aeruginosa Flagellin activates the NLRC4 inflammasome, which supports Caspase-1-driven interleukin (IL)-1β secretion and Gasdermin D (GSDMD)-dependent neutrophil pyroptosis. Furthermore, P. aeruginosa-induced GSDMD activation …

Gender-Based Violence In Pakistan And Public Health Measures: A Call To Action, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Zul Qarnain

Department of Paediatrics and Child Health

No abstract provided.

The Nutritional Quality Of Kids’ Menus From Cafés And Restaurants: An Australian Cross‐Sectional Study, Gina S. A. Trapp, Claire E. Pulker, Miriam Hurworth, Kristy K. Law, Sally Brinkman, Christina M. Pollard, Amelia J. Harray, Ros Sambell, Joelie Mandzufas, Stephanie Anzman‐Frasca, Siobhan Hickling

Research outputs 2022 to 2026

Australian families increasingly rely on eating foods from outside the home, which in-creases intake of energy‐dense nutrient‐poor foods. ‘Kids’ Menus’ are designed to appeal to families and typically lack healthy options. However, the nutritional quality of Kids’ Menus from cafes and full‐service restaurants (as opposed to fast‐food outlets) has not been investigated in Australia. The aim of this study was to evaluate the nutritional quality of Kids’ Menus in restaurants and cafés in metropolitan Perth, Western Australia. All 787 cafes and restaurants located within the East Metropolitan Health Service area were contacted and 33% had a separate Kids’ Menu. The …

The Competitiveness Of Qatari Tourism: A Comparative And Swot Analysis, Ghialy Yap, Shrabani Saha, Saif S. Alsowaidi

Research outputs 2022 to 2026

Purpose: Qatar has placed its tourism sector as one of the main strategies of economic diversification to achieve sustainable tourism goal. The country aims to develop diverse tourism products, ranging from cultural, urban, and nature tourism to education. The government has invested a huge amount in designing and building tourism infrastructures such as the eight new stadiums to host the 2022 World Cup, the national museum, Museum of Islamic Art, Katara Cultural Village, Souq Waqif, and many resorts and high end hotels. Given these significant tourism investments, it is unquestionable that the country reaps commensurate long-term benefits in terms of …

Youth Participation: Adultism, Human Rights And Professional Youth Work, Tim Corney, Trudi Cooper, Harry Shier, Howard Williamson

Research outputs 2022 to 2026

This article argues that the right of young people to participate in decisions being made about them forms the basis for professional youth work practice. The authors consider the nature of ‘participation’ and its relation to human rights, and introduces the concept of ‘adultism’ and the challenges for youth workers combatting ‘adultist’ beliefs and practices in the work of participation. The paper considers the benefits and limitations of youth participation models, and addresses the relationship between rights-based participation practice, and critical pedagogy (dialogical) in youth work.

The Role Of Smoking And Body Mass Index In Mortality Risk Assessment For Geriatric Hip Fracture Patients, Ariana T. Meltzer-Bruhn, Garrett W. Esper, Christopher G. Herbosa, Abhishek Ganta, Kenneth A. Egol, Sanjit R. Konda

2020-Current year OA Pubs

Background Smoking, obesity, and being below a healthy body weight are known to increase all-cause mortality rates and are considered modifiable risk factors. The purpose of this study is to assess whether adding these risk factors to a validated geriatric inpatient mortality risk tool will improve the predictive capacity for hip fracture patients. We hypothesize that the predictive capacity of the Score for Trauma Triage in the Geriatric and Middle-Aged (STTGMA) tool will improve. Methodology Between October 2014 and August 2021, 2,421 patients >55-years-old treated for hip fractures caused by low-energy mechanisms were analyzed for demographics, injury details, hospital quality …

Anticompetitive Merger Review, Samuel N. Weinstein

Articles

U.S. antitrust law empowers enforcers to review pending mergers that might undermine competition. But there is growing evidence that the merger-review regime is failing to perform its core procompetitive function. Industry concentration and the power of dominant firms are increasing across key sectors of the economy. In response, progressive advocates of more aggressive antitrust interventions have critiqued the substantive merger-review standard, arguing that it is too friendly to merging firms. This Article traces the problem to a different source: the merger-review process itself. The growing length of reviews, the competitive restrictions merger agreements place on acquisition targets during review, and …

The Guaranteed Resolution On Effective And Adapted Terms (The Great Process): A New Hybrid Dispute Resolution Process For Guaranteeing A Solution And Resolving Disputes Efficiently, Claude Amar, Véronique Fraser

Cardozo Journal of Conflict Resolution

Over the past twenty years, innovative dispute resolution processes have emerged from practitioners who aimed to tailor them to the parties' process needs. Some of the most widely known processes include med-arb, arb-med, co-mediation with an evaluative and a non-evaluative mediator, baseball arbitration, last offer arbitration, and sealed-arbitration. The list and possible combinations are infinite, when one starts combining processes. However, such spontaneity and adaptivity sometimes result in harmful consequences. In the past, arbitral awards in numerous jurisdictions were refused to be honored on the basis that the process had infringed on fundamental procedural guarantees. For that reason, it is …

State: The Magazine Of Illinois State University, Fall 2022, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine

Acute Otitis Media: Tympanostomy Antibiotics, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Snow Parameters Inversion From Passive Microwave Remote Sensing Measurements By Deep Convolutional Neural Networks, Heming Yao, Yanming Zhang, Lijun Jiang, Hong Tat Ewe, Michael Ng

Electrical and Computer Engineering Faculty Research & Creative Works

This paper proposes a novel inverse method based on the deep convolutional neural network (ConvNet) to extract snow's layer thickness and temperature via passive microwave remote sensing (PMRS). The proposed ConvNet is trained using simulated data obtained through conventional computational electromagnetic methods. Compared with the traditional inverse method, the trained ConvNet can predict the result with higher accuracy. Besides, the proposed method has a strong tolerance for noise. The proposed ConvNet composes three pairs of convolutional and activation layers with one additional fully connected layer to realize regression, i.e., the inversion of snow parameters. The feasibility of the proposed method …

The Wqw Annual Program Report -- July 2022, Bonnie Chapman Beers, Keoki Spaulding, Kicia Sears

Institute for Veterans and Military Families

In early 2021, Warriors & Quiet Waters engaged the Evaluation and Capacity Building team at the IVMF to help measure and communicate the impact of their programs and better tell the story of the participant journey to thriving. The purpose of this evaluation was to test the hypothesis that participants experience a type of transformation or improvement during or immediately after a Fishing Expedition (FX), and that this effect is sustained for some individuals or can be enhanced through participation in additional FXs. Overall, this evaluation found that survey respondents reported improvements in nearly all domains investigated, including the value …

Error Estimate Of A Decoupled Numerical Scheme For The Cahn-Hilliard-Stokes-Darcy System, Wenbin Chen, Shufen Wang, Yichao Zhang, Daozhi Han, Cheng Wang, Xiaoming Wang

Mathematics and Statistics Faculty Research & Creative Works

We analyze a fully discrete finite element numerical scheme for the Cahn-Hilliard-Stokes-Darcy system that models two-phase flows in coupled free flow and porous media. To avoid a well-known difficulty associated with the coupling between the Cahn-Hilliard equation and the fluid motion, we make use of the operator-splitting in the numerical scheme, so that these two solvers are decoupled, which in turn would greatly improve the computational efficiency. The unique solvability and the energy stability have been proved in Chen et al. (2017, Uniquely solvable and energy stable decoupled numerical schemes for the Cahn-Hilliard-Stokes-Darcy system for two-phase flows in karstic geometry. …

Discipleship On The Role And Responsibility Of A Youth Minister, Warren Douglas Choice

Doctoral Dissertations and Projects

The thesis project is designed to equip the congregation at Cary’s Baptist Church to understand the role and responsibility of a youth minister. Cary’s Baptist Church is an older congregation located in Yorktown, Virginia. The congregation was established in the 1800’s and has served the community by sharing the gospel of Jesus Christ and serving individuals who live in the Yorktown community. Throughout the years of serving the community, the congregation has been effective in evangelism and open for youth to be a part of the congregation. However, there has been a decline in youth attendance and involvement in the …

White Coat Hypertension Persistence In Children And Adolescents: The Pediatric Nephrology Research Consortium Study, Yosuke Miyashita, Coral Hanevold, Anna Faino, Julia Scher, Marc Lande, Ikuyo Yamaguchi, Joel Hernandez, Alisa Acosta, Donald J Weaver, Jason Thomas, Mahmoud Kallash, Michael Ferguson, Ketan N Patel, Andrew M South, Megan Kelton, Joseph T Flynn

Faculty, Staff and Students Publications

OBJECTIVES: To determine whether youth with white coat hypertension on initial ambulatory blood pressure monitoring (ABPM) continue to demonstrate the same pattern on repeat ABPM.

STUDY DESIGN: Retrospective longitudinal cohort study of patients referred for high blood pressure (BP) and diagnosed with white coat hypertension by ABPM who had follow-up ABPM 0.5-4.6 years later at 11 centers in the Pediatric Nephrology Research Consortium. We classified ABPM phenotype using the American Heart Association guidelines. At baseline, we classified those with hypertensive BP in the clinic as "stable white coat hypertension," and those with normal BP as "intermittent white coat hypertension." We …

Innovation And Missed Opportunities In Internal Medicine Undergraduate Education During Covid-19: Results From A National Survey, Irene Alexandraki, Katherine J Walsh, Temple Ratcliffe, Chavon Onumah, Karen Szauter, Camilla Curren, Nora Osman, Cindy J Lai, Deborah Dewaay, Nicholas S Duca, Amy Weinstein, Nadia Ismail, Jackcy Jacob, Michael Kisielewski, Amber T Pincavage

Faculty, Staff and Students Publications

BACKGROUND: COVID-19 disrupted undergraduate clinical education when medical schools removed students from clinical rotations following AAMC recommendations. Clerkship directors (CDs) had to adapt rapidly and modify clerkship curricula. However, the scope and effects of these modifications are unknown.

OBJECTIVE: To examine the effects of the initial phase of COVID-19 on the internal medicine (IM) undergraduate clinical education.

DESIGN: A nationally representative web survey.

PARTICIPANTS: IM CDs from 137 LCME-accredited US medical schools in 2020.

MAIN MEASURES: Items (80) assessed clerkship structure and curriculum, assessment in clerkships, post-clerkship IM clinical experiences, and CD roles and support. The framework of Understanding Crisis …

Vibrotactile Perception For Sensorimotor Augmentation: Perceptual Discrimination Of Vibrotactile Stimuli Induced By Low-Cost Eccentric Rotating Mass Motors At Different Body Locations In Young, Middle-Aged, And Older Adults, Ella Pomplun, Ashiya Thomas, Erin Corrigan, Valay A. Shah, Leigh A. Mrotek, Robert A. Scheidt

Biomedical Engineering Faculty Research and Publications

Sensory augmentation technologies are being developed to convey useful supplemental sensory cues to people in comfortable, unobtrusive ways for the purpose of improving the ongoing control of volitional movement. Low-cost vibration motors are strong contenders for providing supplemental cues intended to enhance or augment closed-loop feedback control of limb movements in patients with proprioceptive deficits, but who still retain the ability to generate movement. However, it remains unclear what form such cues should take and where on the body they may be applied to enhance the perception-cognition-action cycle implicit in closed-loop feedback control. As a step toward addressing this knowledge …

Non-Alcoholic Fatty Liver Disease And Depression: Evidence For Genotype × Environment Interaction In Mexican Americans, Eron G. Manusov, Vincent P. Diego, Khalid Sheikh, Sandra Laston, John Blangero, Sarah Williams-Blangero

School of Medicine Publications

This study examines the impact of G × E interaction effects on non-alcoholic fatty liver disease (NAFLD) among Mexican Americans in the Rio Grande Valley (RGV) of South Texas. We examined potential G × E interaction using variance components models and likelihood-based statistical inference in the phenotypic expression of NAFLD, including hepatic steatosis and hepatic fibrosis (identified using vibration controlled transient elastography and controlled attenuation parameter measured by the FibroScan Device). We screened for depression using the Beck Depression Inventory-II (BDI-II). We identified significant G × E interactions for hepatic fibrosis × BDI-II. These findings provide evidence that genetic factors …

Differentiation And Temperature Adaptation Of Pampus Echinogaster Based On Genome-Wide Snps, Yuan Li, Fangrui Lou, Shigang Liu, Hai Li, Jiali Xiang, Binbin Shan, Longshan Lin, Xuan Zhuang

Biological Sciences Faculty Publications and Presentations

Climate change and overfishing have led to the degradation of the quality and stock of Pampus echinogaster. Exploring the genetic structure and local adaptive evolutionary mechanisms of P. echinogaster is crucial for the management of this species. This population genomic study of nine geographical populations of P. echinogaster in China was conducted by specific-locus amplified fragment sequencing (SLAF-seq). A total of 935,215 SLAF tags were obtained, and the average sequencing depth of the SLAF tags was 20.80×. After filtering, a total of 46,187 high-consistency genome-wide single nucleotide polymorphisms (SNPs) were detected. Based on all SNPs, the population size of the …

Mir-181a Promotes Multiple Protumorigenic Functions By Targeting Tgfβr3, Vida Chitsazzadeh, Tran N Nguyen, Alvaro De Mingo Pulido, Bruna B Bittencourt, Lili Du, Charles H Adelmann, Ivannie Ortiz Rivera, Kimberly A Nguyen, Leah D Guerra, Andrew Davis, Marco Napoli, Wencai Ma, Richard Eric Davis, Kimal Rajapakshe, Cristian Coarfa, Elsa R Flores, Kenneth Y Tsai

Faculty, Staff and Students Publications

Cutaneous squamous cell carcinoma (cSCC) comprises 15‒20% of all skin cancers and has a well-defined progression sequence from precancerous actinic keratosis to invasive cSCC. To identify targets for chemoprevention, we previously reported a cross-species analysis to identify the transcriptional drivers of cSCC development and identified miR-181a as a potential oncomiR. We show that the upregulation of miR-181a promotes multiple protumorigenic properties by targeting an understudied component of TGFβ signaling, TGFβR3. miR-181a and TGFβR3 are upregulated and downregulated, respectively, in cSCC. miR-181a overexpression (OE) and TGFβR3 knockdown (KD) significantly suppresses UV-induced apoptosis in HaCaT cells and in primary normal human epidermal …

One Space Can Put Her In A Different Place - How Do We Inhabit Spaces Differently?, Farida Youssef

Theses and Dissertations

In Egypt, a male-dominated society, women are forced to constantly negotiate with patriarchal systems. Dichotomies and paradoxes between principles governing different gendered roles, religion and cultural codes and westernization and commercialization have been continuously shaping Egyptian women’s status over the past decades. This is exhibited in public spaces, where women’s current preferences, perceptions and behavior emphasize the dominance of one gender over the other. This research aims for a better understanding of space inhabitance through a gendered lens. It questions the roles the society and the urban spaces play in the daily lives of women through examining women’s perception of …