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Evaluating Mindfulness On Loneliness In An Older Adult Population, Jessica Tieskoetter Jul 2022

Evaluating Mindfulness On Loneliness In An Older Adult Population, Jessica Tieskoetter

Dissertations

Problem: Loneliness is a widespread public health concern and has negatively impacted mortality and health outcomes among older adults. This quality improvement project’s purpose was to evaluate mindfulness on loneliness and quality of life among adults aged 65 years and older, participating in a weekly befriending socialization program.

Methods: A descriptive cohort design was utilized to assess loneliness pre-and post-implementation of a mindfulness telephone line over three months. A convenience sample of 22 older adults enrolled in a befriending socialization program was used. The Iowa Model of Evidence-Based Practice framework was applied to guide the implementation of a practice change …


When St. Louis School Nature Leaders And Environmental Partners Work Together Nature-Based Learning Inspires Joy And Curiosity In K-2 Students, Julie Frisch, Melissa Politte Jul 2022

When St. Louis School Nature Leaders And Environmental Partners Work Together Nature-Based Learning Inspires Joy And Curiosity In K-2 Students, Julie Frisch, Melissa Politte

Dissertations

This study focused on what values teachers saw in nature-based learning, what outcomes they saw for their students, and what factors have enabled them to do nature-based learning. This explanatory sequential mixed-methods study looked at nature-based learning in St. Louis elementary schools with kindergarten through second-grade students.

We used purposive sampling to choose six schools to examine further through case studies. We then conducted interviews with 8 teachers on qualities of nature-based learning captured in 12 words.

We identified five themes from our interviews and observations: Every School Needs a Nature Champion, Community Bridges in Nature-Based Learning, There is Magic …


Implementing A Standardized Nursing Communication Tool To Improve Inpatient Nursing Communication, Ashley D. Nator Jul 2022

Implementing A Standardized Nursing Communication Tool To Improve Inpatient Nursing Communication, Ashley D. Nator

Dissertations

Implementing a Standardized Nursing Communication Tool to Improve Inpatient Nursing Communication

Ashley D. Nator

B.S. Nursing, University of Missouri-St. Louis, 2018

A Dissertation Submitted to The Graduate School at the University of Missouri-St. Louis in partial fulfillment of the requirements for the degree

Doctor of Nursing Practice with an emphasis in Family Nurse Practitioner

August 2022

Advisory Committee

Cathy Koetting, PhD, DNP, APRN, CPNP, PMHS, FNP-C

Chairperson

Sarah Jackson, DNP, APRN, FNP-C

Amy Terbrock, MSN, PCCN, SCRN, RN

Copyright, Ashley D. Nator, 2021

Original: 08/2021 Revised: 09/2021, 10/2021, 04/2022

Abstract

Problem: Patient handovers occur among nurses more than 4,000 times …


Convergence & Conflict: Reflections On Global And Regional Human Rights Standards On Hate Speech, Evelyn Aswad, David Kaye Jul 2022

Convergence & Conflict: Reflections On Global And Regional Human Rights Standards On Hate Speech, Evelyn Aswad, David Kaye

Northwestern Journal of Human Rights

What is hate speech under international human rights law? And how do key international adjudicators interpret the law governing it? This Article seeks to illuminate two countervailing and under-reported trends: on the one hand, a growing consensus among U.N. experts and treaty bodies concerning interpretations of “hate speech” prohibitions in international law; and on the other, a failure of several regional human rights bodies to develop approaches to hate speech that are consistent with the U.N.’s universal standards. The Article begins by analyzing the U.N.’s approach to freedom of expression and hate speech and examining how, in the last decade, …


Development Experience Of Italian Nutrinform Battery Labeling And Enlightenments, Huang Ze-Ying, Huang Jia-Zhang Jul 2022

Development Experience Of Italian Nutrinform Battery Labeling And Enlightenments, Huang Ze-Ying, Huang Jia-Zhang

Food and Machinery

This study summarized the content, characteristics and development experience of nutrinform battery labeling which launched in 2020 through the official website of Italian government, relevant reports and literatures. The labeling adopted the nutrient profile of specific nutrient system showing contents of energy, fat, saturated fatty acid, sugar, salt and their percentage of adultsʼ reference intakes (RIs) indicated with the battery content. As a voluntary labeling, nutrinform battery labeling which matched the Mediterranean diet pattern, popular in Italy. However, it is counterintuitive to be criticized as "Higher electricity lower nutritional quality" when applying for EU FOP labeling. The practical experience of …


Effect Of Malolactic Fermentation On Volatile Compounds Of Rosa Roxburghii Tratt Wine, Guo Zhi-Jun, Yang Lei, Luo Hong-Xia, Zhou Mo-Mei, Fang Yu-Lin Jul 2022

Effect Of Malolactic Fermentation On Volatile Compounds Of Rosa Roxburghii Tratt Wine, Guo Zhi-Jun, Yang Lei, Luo Hong-Xia, Zhou Mo-Mei, Fang Yu-Lin

Food and Machinery

Objective:The study aimed to analyze the influence of malolactic fermentation on the aroma and deacidification of Rosa roxburghii Tratt wine.Methods:The organic acid content and volatile compounds were qualitatively and quantitatively detected by ion chromatography, HS-SPME/GC-MS and sensory evaluation.Results:The results showed that the malic acid content decreased by 85.83% during malolactic fermentation, with the lactic acid content increasing by 87.75%, 114 kinds of volatile compounds were detected during malolactic fermentation, including 48 kinds of esters (12 011.60 μg/L), 26 alcohols (1 409.50 μg/L), 13 acids (2 490.60 μg/L) and 10 alkane (749.70 μ …


Rapid Determination Of Drug Residues Of Four Kinds Of Tetracyclines Using Des-Uplc-Ms/Ms In Aquatic Products, Liu Zi-Xiong, Xie Guo-Dan, Tan Gui-Liang, Zheng Hong-Tao, Dong Hai, Huang Jing-Hui Jul 2022

Rapid Determination Of Drug Residues Of Four Kinds Of Tetracyclines Using Des-Uplc-Ms/Ms In Aquatic Products, Liu Zi-Xiong, Xie Guo-Dan, Tan Gui-Liang, Zheng Hong-Tao, Dong Hai, Huang Jing-Hui

Food and Machinery

Objective:This study aimed to develop a method of rapid detection of tetracyclines including tetracycline, oxytetracycline, aureomycin and doxycyclin in aquatic products with deep eutectic solvents (DES) extraction and ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).Methods:Different parameters of DES, such as the types of solvents, molar ratio of solvents, water content, and pH value were optimized.Results:The optimum deep eutectic solvent conditions for the medicament analysis of four tetracyclines in aquatic products were choline chloride-glycerol combination(molar ratio 1∶4) with 90% moisture content and 0.1% formic acid. Under the control of these condition, the four types of tetracyclines …


7.7 Nyc Districting Commission Hearing Summary, Piper Benedict Jul 2022

7.7 Nyc Districting Commission Hearing Summary, Piper Benedict

Redistricting Resources

No abstract provided.


The Weekly Challenger, July 7, 2022, The Weekly Challenger, Et Al Jul 2022

The Weekly Challenger, July 7, 2022, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The July 7, 2022, issue of The Weekly Challenger.


Nabat Ml: Utilizing Deep Learning To Enable Crowdsourced Development Of Automated, Scalable Solutions For Documenting North American Bat Populations, Ali Khalighifar, Benjamin S. Gotthold, Erin Adams, Jenny Barnett, Laura O. Beard, Eric R. Britzke, Paul A. Burger, Kimberly Chase, Zackary Cordes, Paul M. Cryan, Emily Emily, Christopher T. Fill, Scott E. Gibson, G. Scott Haulton, Kathryn M. Irvine, Lara S. Katz, William L. Kendall, Christen A. Long, Oisin Mac Aodha, Tessa Mcburney, Sara Mccarthy, Matthew W. Mckown, Joy O'Keefe, Lucy D. Patterson, Kristopher A. Pitcher, Matthew Rustand, Jordi L. Segers, Kyle Seppanen, Jeremy L. Siemers, Christian Stratton, Bethany R. Straw, Theodore J. Weller, Brian E. Reichert Jul 2022

Nabat Ml: Utilizing Deep Learning To Enable Crowdsourced Development Of Automated, Scalable Solutions For Documenting North American Bat Populations, Ali Khalighifar, Benjamin S. Gotthold, Erin Adams, Jenny Barnett, Laura O. Beard, Eric R. Britzke, Paul A. Burger, Kimberly Chase, Zackary Cordes, Paul M. Cryan, Emily Emily, Christopher T. Fill, Scott E. Gibson, G. Scott Haulton, Kathryn M. Irvine, Lara S. Katz, William L. Kendall, Christen A. Long, Oisin Mac Aodha, Tessa Mcburney, Sara Mccarthy, Matthew W. Mckown, Joy O'Keefe, Lucy D. Patterson, Kristopher A. Pitcher, Matthew Rustand, Jordi L. Segers, Kyle Seppanen, Jeremy L. Siemers, Christian Stratton, Bethany R. Straw, Theodore J. Weller, Brian E. Reichert

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

  1. Bats play crucial ecological roles and provide valuable ecosystem services, yet many populations face serious threats from various ecological disturbances. The North American Bat Monitoring Program (NABat) aims to use its technology infrastructure to assess status and trends of bat populations, while developing innovative and community-driven conservation solutions.

  2. Here, we present NABat ML, an automated machine-learning algorithm that improves the scalability and scientific transparency of NABat acoustic monitoring. This model combines signal processing techniques and convolutional neural networks (CNNs) to detect and classify recorded bat echolocation calls. We developed our CNN model with internet-based computing resources (‘cloud environment’), and …


Professor Kate Shaw Comments To Top-Tier Media Outlets On Scotus Dobbs Decision, Benjamin N. Cardozo School Of Law Jul 2022

Professor Kate Shaw Comments To Top-Tier Media Outlets On Scotus Dobbs Decision, Benjamin N. Cardozo School Of Law

Cardozo News 2022

No abstract provided.


Final Portfolio, Denise Mccory Jul 2022

Final Portfolio, Denise Mccory

Master of Arts in English Plan II Graduate Projects

This portfolio contains two projects. The first is an analysis of The Truman Show, which is an American comedy film from 1998. The paper discusses the film’s themes of control, discipline and hyperreality using the perspectives of postmodern theorists Jean Baudrillard and Michel Foucault. The second paper is a teaching-based project that demonstrates how composition instructors can use multimodal texts to teach academic argumentation. The selected projects reflect the variety of research-based knowledge, critical thinking skills, and writing skills that I acquired in the Master of Arts in English program.


Localized Surface Plasmon Resonance Enhancement From Complex Nanoscale Geometries, Jacob T. Waitkus Jul 2022

Localized Surface Plasmon Resonance Enhancement From Complex Nanoscale Geometries, Jacob T. Waitkus

Theses

The unprecedented COVID-19 pandemic highlights the need for portable, sensitive, and accurate biosensors. Here, a novel biosensor that takes advantage of localized surface plasmonic resonance (LSPR) through unique nanoscale geometries was fabricated for sensitive detection of biomarkers. The formation of an adaptable system capable of combining with other sensing methods, such as CRISPR-Cas13a assays, allowed for the detection of specific targets to be realized. In this system, streptavidin-coated gold nanoparticles (GNPs) hybridize with single-stranded RNA (ssRNA) before binding to the surface of gold nanomushrooms (GNMs). Through LSPR enhancement, this binding event produces a red shift in the resonance wavelength peak …


Scale Up Of A Novel Method To Maximize Malonyl-Coa In Escherichia Coli, Clifford Harris Leblanc Iv Jul 2022

Scale Up Of A Novel Method To Maximize Malonyl-Coa In Escherichia Coli, Clifford Harris Leblanc Iv

LSU Master's Theses

The instability of oil’s price along with its limited availability and impact on the environment motivate the search for an alternative feedstock that can sustain the profitability of chemical companies. Industrial biotechnology can promote renewable sources of energy and products by using microorganisms to produce a wide range of chemical compounds. The three-carbon metabolite, malonyl-CoA, can serve as a precursor to a variety of industrial chemicals. The major hurdle with using malonyl-CoA in industry is that its intracellular concentration in Escherichia Coli is very low. Previous attempts to increase the intracellular level of malonyl-CoA have ranged from genetic engineering of …


Genomic Analysis And Therapeutic Development Of Bacteriophages To Treat Bacterial Infections And Parasitic Infestations, Daniel W. Thompson Jul 2022

Genomic Analysis And Therapeutic Development Of Bacteriophages To Treat Bacterial Infections And Parasitic Infestations, Daniel W. Thompson

Theses and Dissertations

Microbiomes are an extremely vast and complex network of microorganisms. Bacteriophages are a key factor in the microbial health of an ecological system and impact the evolution of pathogenic bacterial strains. Bacteria and the phages that infect them have an intricate relationship due to the dependency on the bacterial host for phage replication, the ability of the phage to lyse and kill its host, and the horizontal gene transfer between the host and phage. This thesis aimed to understand how bacteria and the bacteriophages that infect them impact an ecological system, with a focus on disease states. By analyzing all …


A Valley Lost To Time, Washington C. Pearce Jul 2022

A Valley Lost To Time, Washington C. Pearce

Undergraduate Honors Theses

This thesis delivers a playable and functional module for the 5 th Edition of the World’s Greatest Role-Playing Game. The Critical Introduction uses reader response and performance theory to create a framework for reading role-playing games as literature, explains some of the recent scholarship surrounding role-playing games, and details the creative process and work of the creative thesis.

In A Valley Lost to Time, Adventurers recruited by the Trellin Prime Minister are sent westward, over the Drazlin mountain range, with a mission to discover the fate of a decades-lost failed colony. The route is long and treacherous, passing through a …


The Effects Of Overshadowing In Drosophila Melanogaster With Experimentally Evolved Preference, Jill Lee Jul 2022

The Effects Of Overshadowing In Drosophila Melanogaster With Experimentally Evolved Preference, Jill Lee

Theses

As seen in decades of psychology research, preferences play a major role in driving the decision-making process in both humans and animals. Researchers have advocated for using the technique of experimental evolution as a way to address some of the foundational questions on preferences. These preferences can also affect what is later learned and how well new experiences are learned. Salience is usually mentioned as an important component of what could influence preferences. Animals such as Drosophila melanogaster, that lay eggs without any additional maternal or paternal care, it is important to be selective when deciding where to lay …


The Holocaust Paradigm As Paradoxical Imperative In The Century Of Anthropogenic Omnicide, Mark Levene Jul 2022

The Holocaust Paradigm As Paradoxical Imperative In The Century Of Anthropogenic Omnicide, Mark Levene

Genocide Studies and Prevention: An International Journal

The Holocaust and today's climate emergency are not obvious bed fellows. But the post-Holocaust mantra “never again” has also been voiced by some climate activists who see similarities in the failure of Western governments in the 1930s to act to stop Hitler and an equivalent failure now to effectively halt state and corporate drives to biospheric catastrophe. This article examines whether the way Western society has understood the Holocaust in recent decades has relevance to the urge for climate action. It finds the mainstream, state-centred Holocaust paradigm wanting as a framework for empathy and solidarity with those in the Global …


Microfluidic Device For Localized Electroporation, Justin Brooks, Arian Jaberi, Ruiguo Yang Jul 2022

Microfluidic Device For Localized Electroporation, Justin Brooks, Arian Jaberi, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

Electroporation is a common method of transfection due to its relatively low risk and high transfection efficiency. The most common method of electroporation is bulk electroporation which is easily performed on large quantities of cells yet results in variable levels of viability and transfection efficiency across the population. Localized electroporation is an alternative that can be administered on a similar scale but results in much more consistent with higher quality transfection and higher cell viability. This paper discusses the creation and use of a simple and cost-effective device using porous membrane for performing localized electroporation.


Khsrp Loss Increases Neuronal Growth And Synaptic Transmission And Alters Memory Consolidation Through Rna Stabilization, Sarah L. Olguin, Priyanka Patel, Courtney N. Buchanan, Michela Dell'orco, Amy S. Gardiner, Robert Cole, Lauren S. Vaughn, Anitha Sundararajan, Joann Mudge, Andrea M. Allen, Pavel Ortinski, Jonathan L. Brigman, Jeffery L. Twiss, Nora L. Perrone-Bizzozero Jul 2022

Khsrp Loss Increases Neuronal Growth And Synaptic Transmission And Alters Memory Consolidation Through Rna Stabilization, Sarah L. Olguin, Priyanka Patel, Courtney N. Buchanan, Michela Dell'orco, Amy S. Gardiner, Robert Cole, Lauren S. Vaughn, Anitha Sundararajan, Joann Mudge, Andrea M. Allen, Pavel Ortinski, Jonathan L. Brigman, Jeffery L. Twiss, Nora L. Perrone-Bizzozero

Faculty Publications

KH-type splicing regulatory protein (KHSRP) regulates levels of several neuronal mRNAs linked to nervous system development and function.

The KH-type splicing regulatory protein (KHSRP) is an RNA-binding protein linked to decay of mRNAs with AU-rich elements. KHSRP was previously shown to destabilize Gap43 mRNA and decrease neurite growth in cultured embryonic neurons. Here, we have tested functions of KHSRP in vivo. We find upregulation of 1460 mRNAs in neocortex of adult Khsrp(-/-) mice, of which 527 bind to KHSRP with high specificity. These KHSRP targets are involved in pathways for neuronal morphology, axon guidance, neurotransmission and long-term memory. Khsrp(-/-) mice …


Exploring Young Women's Construction Of Social And Political Communicative Realities, Lindsay Strodbeck, Sheila Kiss, Sarah M. Green, Dylan Glover, Molly Weir, Lily Stockbridge, Richard M. Perloff Jul 2022

Exploring Young Women's Construction Of Social And Political Communicative Realities, Lindsay Strodbeck, Sheila Kiss, Sarah M. Green, Dylan Glover, Molly Weir, Lily Stockbridge, Richard M. Perloff

Student Scholarship

The time-honored role that communication plays in the symbolic construction of young adults’ reality is always changing, perhaps no more so than in the age of ubiquitous global media. Yet research on how young people construct contemporary social media and political experiences is lacking. This panel, designed to extend research, reports the results of a qualitative examination of young women’s experiences with two salient aspects of contemporary life: the social, focusing on their parasocial involvement with social media influencers, but also the more politically consequential arena, with a look at the development of political attitudes as a function of political …


Evidence-Based Intervention (Ebi) Mapping: A Systematic Approach To Understanding The Components And Logic Of Ebis, Timothy J Walker, Maya Foster, Jacob Szeszulski, Derek W Craig, Patricia Dolan Mullen, Maria E Fernández Jul 2022

Evidence-Based Intervention (Ebi) Mapping: A Systematic Approach To Understanding The Components And Logic Of Ebis, Timothy J Walker, Maya Foster, Jacob Szeszulski, Derek W Craig, Patricia Dolan Mullen, Maria E Fernández

Faculty, Staff and Student Publications

BACKGROUND: Despite the development of numerous evidence-based interventions (EBIs), many go unused in practice. Hesitations to use existing EBIs may be due to a lack of understanding about EBI components and what it would take to adapt it or implement it as designed. To improve the use of EBIs, program planners need to understand their goals, core components, and mechanisms of action. This paper presents EBI Mapping, a systematic approach based on Intervention Mapping, that can be used to understand and clearly describe EBIs, and help planners put them into practice.

METHODS: We describe EBI Mapping tasks and provide an …


Dissecting The Treatment-Naive Ecosystem Of Human Melanoma Brain Metastasis, Jana Biermann, Johannes C Melms, Amit Dipak Amin, Yiping Wang, Lindsay A Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A Ibarra-Arellano, Massimo Andreatta, Benjamin T Fullerton, Kristjan H Gretarsson, Varun Sahu, Vaibhav S Mangipudy, Trang T T Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D Koch, Matei Banu, Nelson Humala, Aayushi Mahajan, Zachary H Walsh, Shivem B Shah, Daniel H Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne M Luoma, Joseph Driver, Matthew Ingham, Shaheer A Khan, Suthee Rapisuwon, Craig L Slingluff, Thomas Eigentler, Martin Röcken, Richard Carvajal, Michael B Atkins, Michael A Davies, Albert Agustinus, Samuel F Bakhoum, Elham Azizi, Markus Siegelin, Chao Lu, Santiago J Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z Macosko, Fei Chen, Gary K Schwartz, Benjamin Izar Jul 2022

Dissecting The Treatment-Naive Ecosystem Of Human Melanoma Brain Metastasis, Jana Biermann, Johannes C Melms, Amit Dipak Amin, Yiping Wang, Lindsay A Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A Ibarra-Arellano, Massimo Andreatta, Benjamin T Fullerton, Kristjan H Gretarsson, Varun Sahu, Vaibhav S Mangipudy, Trang T T Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D Koch, Matei Banu, Nelson Humala, Aayushi Mahajan, Zachary H Walsh, Shivem B Shah, Daniel H Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne M Luoma, Joseph Driver, Matthew Ingham, Shaheer A Khan, Suthee Rapisuwon, Craig L Slingluff, Thomas Eigentler, Martin Röcken, Richard Carvajal, Michael B Atkins, Michael A Davies, Albert Agustinus, Samuel F Bakhoum, Elham Azizi, Markus Siegelin, Chao Lu, Santiago J Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z Macosko, Fei Chen, Gary K Schwartz, Benjamin Izar

Faculty, Staff and Student Publications

Melanoma brain metastasis (MBM) frequently occurs in patients with advanced melanoma; yet, our understanding of the underlying salient biology is rudimentary. Here, we performed single-cell/nucleus RNA-seq in 22 treatment-naive MBMs and 10 extracranial melanoma metastases (ECMs) and matched spatial single-cell transcriptomics and T cell receptor (TCR)-seq. Cancer cells from MBM were more chromosomally unstable, adopted a neuronal-like cell state, and enriched for spatially variably expressed metabolic pathways. Key observations were validated in independent patient cohorts, patient-derived MBM/ECM xenograft models, RNA/ATAC-seq, proteomics, and multiplexed imaging. Integrated spatial analyses revealed distinct geography of putative cancer immune evasion and evidence for more abundant …


Entertainment Media, Propaganda, And Popular Support : Evidence From China, Shouzhi Xia Jul 2022

Entertainment Media, Propaganda, And Popular Support : Evidence From China, Shouzhi Xia

Lingnan Theses (MPhil & PhD)

Is it possible to form “soft authoritarianism” that manages citizens by taking away their sense of resistance? Taking China as a case, this dissertation suggests that the rise of entertainment media in authoritarian states enables the rulers to maintain their resilience through a soft approach, thereby avoiding costly heavy-handed measures. Such a soft approach can work because entertainment media, like “fictitious pleasure drugs,” undoes audiences’ sophistication so that people are susceptible to official propaganda.

We provide two pieces of evidence that the Chinese authorities may use entertainment media as a subtle means to manage society. First, analyzing the Weibo posting …


Antología Volumen Ii: Cuento, Poesía, Relato, Microrrelato Y Testimonio, Jose Higuera Lopez, Carlos Aguasaco Jul 2022

Antología Volumen Ii: Cuento, Poesía, Relato, Microrrelato Y Testimonio, Jose Higuera Lopez, Carlos Aguasaco

CUNY Mexican Studies Institute

La Feria Internacional del Libro de la Ciudad de Nueva York es un espacio donde se promueve la riqueza expresiva de la literatura en español en Estados Unidos. Las obras inéditas que se compilan en este volumen expresan la gran diversidad de texturas y acentos que dan cuenta de la infinitud de nuestra lengua.

La Antología de la FIL Ciudad de Nueva York es uno de los proyectos fundamentales dentro de las iniciativas de nuestra Feria, y su objetivo es proveer un espacio de visibilidad y desarrollo para las voces emergentes, así como un punto de encuentro para escritores y …


Small Rna Signatures Of Acute Ischemic Stroke In L1cam Positive Extracellular Vesicles, Michael A Lopez, Ying Si, Xianzhen Hu, Valentyna Williams, Fuad Qushair, Jackson Carlyle, Lyndsy Alesce, Michael Conklin, Shawn Gilbert, Marcas M Bamman, Matthew S Alexander, Peter H King Jul 2022

Small Rna Signatures Of Acute Ischemic Stroke In L1cam Positive Extracellular Vesicles, Michael A Lopez, Ying Si, Xianzhen Hu, Valentyna Williams, Fuad Qushair, Jackson Carlyle, Lyndsy Alesce, Michael Conklin, Shawn Gilbert, Marcas M Bamman, Matthew S Alexander, Peter H King

Faculty, Staff and Student Publications

Duchenne muscular dystrophy (DMD) is an X-linked recessive disease characterized by skeletal muscle instability, progressive muscle wasting, and fibrosis. A major driver of DMD pathology stems from aberrant upregulation of transforming growth factor β (TGFβ) signaling. In this report, we investigated the major transducers of TGFβ signaling, i.e., receptor Smads (R-Smads), in DMD patient skeletal muscle and observed a 48-fold increase in Smad8 mRNA. Smad1, Smad2, Smad3, and Smad5 mRNA were only minimally increased. A similar pattern was observed in the muscle from the mdx5cv mouse. Western blot analysis showed upregulation of phosphorylated Smad1, Smad5, and Smad8 …


Tuberculosis Phenotypic And Genotypic Drug Susceptibility Testing And Immunodiagnostics: A Review, Kizil A. Yusoof, Juan Ignacio Garcia, Alyssa Schami, Andreu Garcia-Vilanova, Holden V. Kelley, Shu-Hua Wang, Adrian Rendon, Blanca I. Restrepo, Marcel Yotebieng, Jordi B. Torrelles Jul 2022

Tuberculosis Phenotypic And Genotypic Drug Susceptibility Testing And Immunodiagnostics: A Review, Kizil A. Yusoof, Juan Ignacio Garcia, Alyssa Schami, Andreu Garcia-Vilanova, Holden V. Kelley, Shu-Hua Wang, Adrian Rendon, Blanca I. Restrepo, Marcel Yotebieng, Jordi B. Torrelles

School of Medicine Publications

Tuberculosis (TB), considered an ancient disease, is still killing one person every 21 seconds. Diagnosis of Mycobacterium tuberculosis (M.tb) still has many challenges, especially in low and middle-income countries with high burden disease rates. Over the last two decades, the amount of drug-resistant (DR)-TB cases has been increasing, from mono-resistant (mainly for isoniazid or rifampicin resistance) to extremely drug resistant TB. DR-TB is problematic to diagnose and treat, and thus, needs more resources to manage it. Together with+ TB clinical symptoms, phenotypic and genotypic diagnosis of TB includes a series of tests that can be used on different specimens to …


Structural And Electrical Remodeling Of The Sinoatrial Node In Diabetes: New Dimensions And Perspectives, Lina T. Al Kury, Stephanie Chacar, Eman Alefishat, Ali A. Khraibi, Moni Nader Jul 2022

Structural And Electrical Remodeling Of The Sinoatrial Node In Diabetes: New Dimensions And Perspectives, Lina T. Al Kury, Stephanie Chacar, Eman Alefishat, Ali A. Khraibi, Moni Nader

All Works

The sinoatrial node (SAN) is composed of highly specialized cells that mandate the spontaneous beating of the heart through self-generation of an action potential (AP). Despite this automaticity, the SAN is under the modulation of the autonomic nervous system (ANS). In diabetes mellitus (DM), heart rate variability (HRV) manifests as a hallmark of diabetic cardiomyopathy. This is paralleled by an impaired regulation of the ANS, and by a pathological remodeling of the pacemaker structure and function. The direct effect of diabetes on the molecular signatures underscoring this pathology remains ill-defined. The recent focus on the electrical currents of the SAN …


Gender Equity And State-Mosque Relations In Middle East North Africa: A Case Study Of Tunisia, Joy Amarachi Agbugba Jul 2022

Gender Equity And State-Mosque Relations In Middle East North Africa: A Case Study Of Tunisia, Joy Amarachi Agbugba

Dissertations and Theses

Why is the Middle East North Africa region consistently ranked the lowest on the gender equity scale? This question is quite perplexing and that has driven several scholarly researchers to investigate the situation of gender and women's rights within the states in the region. In this research, I explore the various theories explaining the cause of gender inequity in this region including the Islam thesis/social modernization theory, political-economic theory, and psychological/social structural theories, with an emphasis on the Islamic thesis theory. I argue that the state's support and prioritization of Muslim/sharia law over federal law is a major contributor to …


The Paratexts Of Audience Engagement: Cover Matter That Draws In And Keeps Readers, Athena L. Edwards Jul 2022

The Paratexts Of Audience Engagement: Cover Matter That Draws In And Keeps Readers, Athena L. Edwards

All HCAS Student Capstones, Theses, and Dissertations

Within the book publishing industry, purchase statistics often determine a book’s success. This metric neglects crucial factors of reader engagement (i.e., reception and anticipation of current and future work) such as level of interest and appreciation. By blending key concepts from work on assemblage, ecology, reader-response, audience invoked, and media studies, this thesis attempts to (re)invigorate the discourse of book paratexts’ role in inspiring reader engagement. As a manifestation of various voices performing and contextualizing a core text for readers, paratexts are a key component to the discursive uptake of books by readers and their publics. Book covers, specifically, are …