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Articles 7921 - 7950 of 1738424
Full-Text Articles in Entire DC Network
Stewardship In Action: Reducing Unnecessary Antimicrobial Use In Long-Term Care, Mariatu Sulaiman
Stewardship In Action: Reducing Unnecessary Antimicrobial Use In Long-Term Care, Mariatu Sulaiman
Walden Dissertations and Doctoral Studies
Antimicrobial overuse in long-term care facilities (LTCFs) contributes to antimicrobial resistance, avoidable healthcare costs, and adverse drug events, particularly when antibiotics are prescribed for asymptomatic bacteriuria rather than symptomatic urinary tract infections (UTIs). Evidence-based clinical practice guidelines, including the McGeer Criteria, provide standardized approaches for differentiating true UTIs from asymptomatic bacteriuria and supporting appropriate antimicrobial prescribing. The purpose of this evidence-based practice project was to evaluate the development and implementation of a clinical practice guideline incorporating the McGeer Criteria into an antibiotic stewardship program in an LTCF. The practice-focused question examined what evidence supports strategies for reducing unnecessary antimicrobial use …
Elementary Teachers’ Perceptions About Teaching Students With Disabilities In The General Education Classroom, Mackenzie Rathburn
Elementary Teachers’ Perceptions About Teaching Students With Disabilities In The General Education Classroom, Mackenzie Rathburn
Walden Dissertations and Doctoral Studies
The problem that was addressed through this study is that elementary teachers encounter challenges to meet the diverse needs of students with disabilities (SWDs) in Georgia’s general education classrooms, despite policy mandates requiring inclusive education. Grounded in Ajzen’s theory of planned behavior, the purpose of this basic qualitative study was to explore elementary teachers’ perceptions of the challenges they face and the resources and supports recommended to teach SWDs in general education classrooms. Data were collected through semistructured interviews with 10 elementary general education teachers and analyzed using thematic analysis with the following six themes emerging: Teachers noted (1) instructional …
Operating Room Scheduling And Workflow Optimization In Acute Care Hospitals, Waleed Tawfik
Operating Room Scheduling And Workflow Optimization In Acute Care Hospitals, Waleed Tawfik
Walden Dissertations and Doctoral Studies
Operating room scheduling inefficiencies in acute care hospitals contribute to delays, prolonged turnover times, cancellations, underused capacity, overtime, higher costs, and reduced timely access to surgery. This integrative review examined evidence-based, systems-oriented scheduling and workflow strategies to improve operating room utilization, reduce delays, and enhance operational efficiency. Guided by general systems theory, a structured search identified 196 database-level records; 28 articles underwent full-text review, and 20 sources were retained for thematic synthesis after critical appraisal using the Johns Hopkins Evidence-Based Practice criteria. The thematic analysis revealed four main themes: standardized workflow coordination, data-driven scheduling and decision support, integrated resource and …
The Gap Kalamazoo Instrument To Evaluate Therapeutic Communication Of Pre-Licensure Nursing Students, Tracy J. Perron, Mary Thomas, Chelsea Lebo, Romy Zemer
The Gap Kalamazoo Instrument To Evaluate Therapeutic Communication Of Pre-Licensure Nursing Students, Tracy J. Perron, Mary Thomas, Chelsea Lebo, Romy Zemer
International Nursing Research Congress (INRC)
Background: Effective communication among healthcare teams is essential for patient safety and satisfaction. Communication is a core competency for students in nursing education.
Purpose: This study aims to adapt the Gap-Kalamazoo Communication Skills Assessment for nursing students to enhance their communication skills and align with the American Association of Colleges of Nursing Essentials competencies.
Methods: This tool was tested with junior and senior nursing students at two institutions, with data collected through self-evaluations, peer evaluations, and faculty evaluations during clinical and simulation experiences.
Results: The results showed a high reliability of the tool (Cronbach’s Alpha 0.832 for seniors, 0.880 for …
Silver Linings Among Youth Living With Hiv: An Integrated Mixed Methods Analysis, Emily Anne Barr, Mary Catherine Lingwall, Himabindu Reddy Basani, Joanna S. Vennekotter, Alyssa Goldsmith, Joseph Crane, Leah Jane Anthony, Re'undre Malone, Veronica Brady
Silver Linings Among Youth Living With Hiv: An Integrated Mixed Methods Analysis, Emily Anne Barr, Mary Catherine Lingwall, Himabindu Reddy Basani, Joanna S. Vennekotter, Alyssa Goldsmith, Joseph Crane, Leah Jane Anthony, Re'undre Malone, Veronica Brady
International Nursing Research Congress (INRC)
Purpose: Youth living with HIV experience stigma, mental health challenges, and barriers to engagement in care. Silver linings are positive shifts in perception, connection, or opportunity that arise from adversity. This project examined silver linings across two studies of youth living with HIV and explored associations with stigma, trust, mental health, and viral suppression.
Methods: An integrated mixed methods design was used. The first study (Colorado, USA) was a cross-sectional survey of 109 youth that assessed stigma, mental health, trust in the healthcare relationship, viral load, and one open-ended item on silver linings. The second study (Texas, USA) included semi-structured …
Pre-Implementation Factors For Active Music Engagement (Ame): Barriers And Facilitators To Integrating An Evidence-Based Dyadic Intervention Into Pediatric Oncology Care., Kristin M. Story, Elizabeth Harman, Kristin Stegenga, Jelena Golubovic, Sheri L. Robb
Pre-Implementation Factors For Active Music Engagement (Ame): Barriers And Facilitators To Integrating An Evidence-Based Dyadic Intervention Into Pediatric Oncology Care., Kristin M. Story, Elizabeth Harman, Kristin Stegenga, Jelena Golubovic, Sheri L. Robb
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Pediatric cancer treatment is a difficult and distressing experience that often results in sustained, interrelated distress in young children and parents, and traumatic stress symptoms for some parents. Few evidence-based interventions address this dyadic distress. Active Music Engagement (AME) is a manualized, evidence-based music play intervention that significantly reduces distress in child/parent dyads and mitigates traumatic stress and improves well-being among highly distressed parents and those experiencing sociodemographic risk. Successfully integrating AME into standard care requires a systematic understanding of implementation factors. This study aimed to identify site-specific barriers and facilitators that influenced successful AME delivery during a recently …
Listening, Learning, Accommodating: A Critical Look At Inclusive Research Help, Michelle Lee, Laura Beane, Kristina Lang, Jillian Speck, Kristina Clement
Listening, Learning, Accommodating: A Critical Look At Inclusive Research Help, Michelle Lee, Laura Beane, Kristina Lang, Jillian Speck, Kristina Clement
Faculty Articles
Research consultations continue to be a valuable means of connecting with users and supporting their research needs. As we’ve received an increasing number of research consultations where one or more accommodations have been requested, the Kennesaw State University Libraries have been exploring ways to provide accommodations in research consultations. Since there is a lack of research on this specific facet of research consultations, this literature review focuses on the related topics of assistive technology in libraries, accommodations in library services and spaces, and library anxiety to show how these topics relate to providing accommodations in research consultations. The objective of …
Sac Newsletter 2026, South Asia Center
Sac Newsletter 2026, South Asia Center
Newsletters from the South Asia Center
No abstract provided.
Strategic Information System Leadership And Information System Function Performance In Universities In Kenya: A Pls-Sem Analysis, Joseph K. Muchina, James M. Njihia Prof., Agnes N. Wausi Prof.
Strategic Information System Leadership And Information System Function Performance In Universities In Kenya: A Pls-Sem Analysis, Joseph K. Muchina, James M. Njihia Prof., Agnes N. Wausi Prof.
International Journal of Applied Management and Technology
Information systems as enablers have evolved from an efficiency and effectiveness focus to enterprise-wide performance, placing strong demands on information system leadership. Emerging leadership models call for collaborative practices. Information systems leadership in higher education is a challenging task. Universities' top management team members and their information system executive counterparts lack a common and shared vision and understanding of information systems capabilities and roles. As the highest-ranking officers in organizations, they make strategic IS decisions. Yet, noting that existing approaches are ineffective, there is a growing concern about the kind of leadership needed to guide the institutions. Four sets of …
Bcg Overexpressing Ag85b Reprograms Host Immune Response Through Coordinated Transcriptional Networks, Vivek Chauhan, Rakesh Kumar, Raja Veerapandian, Enrique I. Ramos, Chinnaswamy Jagannath, Shrikanth Gadad, Subramanian Dhandayuthapani
Bcg Overexpressing Ag85b Reprograms Host Immune Response Through Coordinated Transcriptional Networks, Vivek Chauhan, Rakesh Kumar, Raja Veerapandian, Enrique I. Ramos, Chinnaswamy Jagannath, Shrikanth Gadad, Subramanian Dhandayuthapani
School of Medicine Publications
Antigen 85B (Ag85B), an immunodominant protein secreted by Mycobacterium tuberculosis (Mtb), induces robust T-cell-mediated immunity in host cells. Previous studies have demonstrated that recombinant BCG strains overexpressing Ag85B (BCG85B) confer significant protection against tuberculosis in mouse models. This study hypothesized that enhanced protection by recombinant BCG85B results from modulation of host immune gene expression by the Ag85B antigen. To test this, RNA-seq analysis was performed on splenocytes from mice immunized with the wild-type BCG (BCG-WT) and BCG85B strains. Differentially expressed genes (DEGs) in the splenocytes of BCG85B-immunized mice indicated upregulation of immune-related KEGG pathways, including Th1/Th2 and Th17 differentiation, NF-kappa …
"Tithing Is An Insurance Premium": A Framing Analysis Of Speaker Innovation And Diachronic Trends In Latter-Day Saint Religious Discourse, Reid Empey
Theses and Dissertations
Religious language relies on shared metaphor and frames that contextualize religious experience and practice. Current approaches to frame semantics (Fillmore 1982) and cognitive metaphor (Lakoff & Johnson 1980) lend important insight into religious language, particularly in describing the role that figurative language serves in a religious speech community. However, a vital component of many religious speech communities is the presence of and engagement with a scriptural canon, which often contains metaphorical and framing language that religious speakers can directly reference. Yet, past conceptualizations of speech communities have not accounted for this engagement with a shared canon. To illustrate the role …
Synthetic Strategies For Bioactive Peptides: From Aggregation Inhibitors To The Total Synthesis Of Tunicyclin C, Stephanie Graciela Garcia Morin
Synthetic Strategies For Bioactive Peptides: From Aggregation Inhibitors To The Total Synthesis Of Tunicyclin C, Stephanie Graciela Garcia Morin
Theses and Dissertations
In Alzheimer's disease (AD), a brain protein called "tau" abnormally clumps and forms neurofibrillary tangles (NFTs), causing damage to brain cells. Ac-PHF6-NH2 is a hexapeptide segment of tau protein that plays a dominant role in tau aggregation and is used as a model to design tau protein aggregation inhibitors. In this research we synthesized four dehydroamino acid (□AA) containing PHF6 analogues with △Abu (derived from L-threonine) and △Val (derived from □-OH-Valine) at position 2 or 3 via dehydrations or azlactone ring-openings as key reactions. We evaluated their proteolytic resistance, ability to inhibit aggregation of PHF6, and impact on the morphology …
Standardizing Gestational Diabetes Mellitus Education To Improve Patient Knowledge And Care Consistency In A Prenatal Clinic Setting, Wynn Zara
Master's Projects and Capstones
The gestational diabetes mellitus (GDM) group visit framework aims to improve consistency of GDM education by standardizing referral processes, educational materials, staff workflows, and patient communication. Although evidence-based GDM education supports patient self-management and improved maternal-fetal outcomes, variability in education delivery contributed to inconsistent care within the outpatient maternal-fetal medicine setting. This quality improvement project was conducted in an outpatient maternal-fetal medicine clinic in Santa Clara County serving pregnant patients diagnosed with GDM. To address this gap, a standardized GDM group visit framework was developed and implemented using structured educational resources, referral criteria, and communication workflows. The intervention was evaluated …
Children Second Dialect Acquisition In North America, Iqbal Nurul Azhar, Mohammad Halili
Children Second Dialect Acquisition In North America, Iqbal Nurul Azhar, Mohammad Halili
Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya
This article aims to examine the causes, social contributing factors, and the linguistic consequences of Second Dialect Acquisition (SDA henceforth) in children in North America, drawing on relevant articles. For children growing up in a monolingual region but then must live in a new space, acquiring second dialect can pave them to improve their communication skills, adjust their social and identity belonging. Yet why, how, and the linguistic consequence of SDA require further studies. We used the thematic synthesis in reviewing the existing related literature based on three steps: article identification, selection, and analysis. Six causes of SDA were found: …
Development And Validation Of The Global Impact Of Chronic Illness Scale – Universal, Abigail Kukay
Development And Validation Of The Global Impact Of Chronic Illness Scale – Universal, Abigail Kukay
Theses and Dissertations
The current manuscript presents the development and validation of the Global Impact of Chronic Illness Scale – Universal (GICIS-U), a novel measure of chronic illness impact through three separate studies. The pilot study aimed at measure development, which included item selection and two rounds of item refinement using feedback gained through four focus groups. Study 1 consisted of an exploratory factor analysis (EFA) to determine factor structure of the measure. Participants were 183 individuals recruited from an online participant pool and social media outlets who completed the refined GICIS-U online. Results of the EFA suggested a six-factor structure, of which …
Engineering Education Beyond The Engineering Classroom: Three Studies On Behavioral Nudges, General Education Completion, And Honors Program Participation, Andrew Harrison Volk
Engineering Education Beyond The Engineering Classroom: Three Studies On Behavioral Nudges, General Education Completion, And Honors Program Participation, Andrew Harrison Volk
Theses and Dissertations
Engineering education extends well beyond the engineering classroom. Engineering undergraduates progress through general education courses, institutional support structures, and enrichment opportunities operating outside their major. The administrative offices that shape these non-engineering experiences typically operate independently of engineering departments, and the structural decisions they make can shape the engineering student's experience without engineering's input. This dissertation examines three settings in which decisions outside engineering matter for engineering students. Study 1 reports a PRISMA-format systematic review of nudge interventions in higher education, developing a four-category typology of nudge types (informational, environmental, process-oriented, and in-name-only) and a six-category typology of application domains. …
Thermomechanical Characterization And Modeling Of An Smp-Epoxy Composite For Deployable Space Structures, Ap Anshuman Behera
Thermomechanical Characterization And Modeling Of An Smp-Epoxy Composite For Deployable Space Structures, Ap Anshuman Behera
Theses and Dissertations
Deployable space structures can be stowed in a compact form and later allowed to their operational shape. Carbon fiber reinforced polymer (CFRP) composites have been utilized as a material candidate due to their increased strength-to-weight ratio and tailored performance. Current challenges associated with CFRP composites are driven by the viscoelastic nature of the polymer matrix causing long-term stowage effects and deployment issues such as shape deformation and incomplete recovery. In this study, a shape memory polymer (SMP) is presented as a potential option in mitigating these issues. An epoxy SMP is synthesized and experimentally characterized and its performance in the …
Ocean Salinity Effects On Lightning Frequency And Distribution In The Inner Core Of Tropical Cyclones In The Atlantic Basin, Desiree Knight
Ocean Salinity Effects On Lightning Frequency And Distribution In The Inner Core Of Tropical Cyclones In The Atlantic Basin, Desiree Knight
Theses and Dissertations
Different oceanic salinity profiles seen in the Atlantic have been found to influence tropical cyclone (TC) intensity. With the freshwater plume from the Amazon-Orinoco reaching into a TC development region during peak hurricane season, the stable ocean feature it creates has effects on SST, ocean mixing, enthalpy fluxes, and convection. This study investigates the relationship between sea surface salinity (SSS) and inner-core lightning of north Atlantic TCs and further explores the spatial variations of this relationship with TC intensity. SSS values are collocated with lightning flashes, which are split between “fresher” and “saltier” waters. Further investigations found that TCs have …
How Family Functioning Impacts Adolescent Outcomes: The Roles Of Cohesion, Flexibility, Communication, Satisfaction, And The Family Environment On Well-Being Across Levels Of Family Complexity, Emily E. Shaw
Theses and Dissertations
This dissertation research is a combination of two studies. The overarching and guiding focus for this study involved how family functioning and environments influence adolescent psychological well-being, and do these associations vary based on levels of family complexity. Study 1 examined family complexity and family environments as potential predictors of family functioning, while Study 2 examined family functioning and family complexity as potential predictors of adolescent negative (i.e., anxiety and depression) and positive (i.e., engagement, perseverance, optimism, connectedness, and happiness) well-being. In Study 1, family complexity was not predictive of family functioning, but the family environment was a strong predictor. …
Enhancing Levee Resilience With Biopolymers To Reduce Erosion And Improve Overtopping Performance, Ethan Tyler Vroman
Enhancing Levee Resilience With Biopolymers To Reduce Erosion And Improve Overtopping Performance, Ethan Tyler Vroman
Theses and Dissertations
Levee breaches from overtopping erosion present a significant flood risk across the US. Biopolymers have been proposed as a soil-stabilization method for embankments to improve slope stability and mitigate erosion. This study evaluates the technical and economic efficacy of two biopolymers, Rhizobium tropici (RT) and Xanthan gum (XG). Silt treated with 1% biopolymer was subjected to five wetting-drying cycles to assess erosion performance and durability. Laboratory testing revealed significant, temporary improvements to mechanical properties. Compared to untreated soil, RT and XG treatments increased critical shear stress by nearly one order of magnitude and more than an order of magnitude, respectively, …
Comparative Analysis Of Spray Pattern Deposition In Commercial-Off-The-Shelf (Cots) U.S.-Manufactured Uncrewed Aerial Application System (Uaas), James Mackey Ikerd Ii
Comparative Analysis Of Spray Pattern Deposition In Commercial-Off-The-Shelf (Cots) U.S.-Manufactured Uncrewed Aerial Application System (Uaas), James Mackey Ikerd Ii
Theses and Dissertations
Uncrewed aerial application systems (UAAS) are increasingly used for agricultural spraying, but spray deposition uniformity and effective swath width can vary between platforms. This study evaluated spray-pattern deposition and effective swath width for two commercial off-the-shelf (COTS) UAAS platforms during manual and autonomous flight operations. Manual, single-pass testing was used to assess preliminary performance and spray characteristics for both UAAS. Further autonomous multi-pass and single-pass evaluations were conducted to assess deposition uniformity and in-swath variability for both UAAS utilizing two methods of evaluation: Operation Self-regulating Application & Flight Efficiency (S.A.F.E.) pattern testing for manual flight evaluation and the Swath Gobbler …
A Study On The Welfare And Crop-Residue Ameliorating Potential Of Acheta Domesticus In The Context Of Insect Sequestration, Metabolism, And Excretion Of Three Mycotoxins: Aflatoxin B1, Deoxynivalenol, And Zearalenone, Ryan Thomas Paulk
Theses and Dissertations
Mycotoxins are a food security issue that affects all crops globally, but to varying degrees, due to the ubiquity of fungi that produce them. Developing new agricultural practices that can ameliorate lost nutrients post-contamination by removing mycotoxins for the next levels in the food chain can remedy an inevitable effluent in the circular economy. Farmed insects, such as the house cricket, Acheta domesticus, can potentially consume moldy, mycotoxin contaminated grains safely without transferring them to other trophic levels. The experiments herein test the biology of A. domesticus to consume three individual mycotoxins: aflatoxin B1, deoxynivalenol, and zearalenone. In addition to …
Improving The Hemp Fiber Supply Chain: Barriers, Innovations, And Regulatory Impacts, Sneha Chapagain
Improving The Hemp Fiber Supply Chain: Barriers, Innovations, And Regulatory Impacts, Sneha Chapagain
Theses and Dissertations
The hemp fiber sector in the United States has seen significant growth challenges, including a lack of processing infrastructure, inconsistent regulations, and limited research. The Theory of Constraints and Systems Engineering frameworks are used in this study to carefully analyze these difficulties. The study identifies important bottlenecks, investigates system-wide inefficiencies, and examines the impact of regulatory complexity using a survey of key supply chain stakeholders. The findings emphasize the need for more processing capacity, better coordination among supply chain actors, and more policy harmonization. The report also identifies stakeholder-driven improvements in technology, transportation, and market integration that could boost efficiency …
Toward Secure Genomic Intelligence: Privacy-Preserving Deep Learning Frameworks For Cancer Classification And Collaborative Analysis, Yibo Dong
Theses and Dissertations
Genomic data contains highly sensitive personal information, yet cancer classification and collaborative medical research increasingly depend on sharing such data across institutions. Existing privacy-preserving approaches for deep learning, including differential privacy (DP) and standard federated learning (FL), leave critical vulnerabilities: DP degrades model utility through noise injection, while FL relies on a trusted aggregation server that remains susceptible to gradient-based attacks. This dissertation develops, evaluates, and optimizes a series of privacy-preserving deep learning frameworks specifically designed for genomic cancer classification. First, a systematic benchmarking study evaluates DP, FL, and fully homomorphic encryption (FHE) across three deep learning architectures (fully connected …
Staff Education To Improve Obesity Risk Assessment And Referral Practices, Omolara Aminat Oshokoya
Staff Education To Improve Obesity Risk Assessment And Referral Practices, Omolara Aminat Oshokoya
Walden Dissertations and Doctoral Studies
Summary This staff education project addressed inconsistent obesity risk assessment practices in an adult primary care setting. Obesity is associated with increased rates of cardiovascular disease, diabetes, hypertension, and other chronic conditions. At the project site, obesity assessment practices relied largely on body mass index (BMI), resulting in inconsistent identification of obesity-related risks and referral needs. The purpose of this project was to educate providers on the Edmonton Obesity Staging System (EOSS) to improve obesity risk identification and referral practices. The project evaluated whether the staff education intervention improved providers' knowledge and use of the Edmonton Obesity Staging System (EOSS) …
Instruction Guide, Mark C. Hall
Instruction Guide, Mark C. Hall
Analytical Biochemistry: A Practical Handbook for Undergraduates
The instruction guide provides useful information for setting up and running the lab activities each week and assessing student preparation, performance, and comprehension.
Psychological Interventions For Children With Neurodevelopmental Disabilities In The Context Of Neurodiversity: A Systematic Review, Kalliopi Megari, Dimitra V. Katsarou, Evangelos Mantsos, Soultana Papadopoulou, Efthymia Efthymiou, Maria Theodoratou, Maria Sofologi, Eugenia Toki
Psychological Interventions For Children With Neurodevelopmental Disabilities In The Context Of Neurodiversity: A Systematic Review, Kalliopi Megari, Dimitra V. Katsarou, Evangelos Mantsos, Soultana Papadopoulou, Efthymia Efthymiou, Maria Theodoratou, Maria Sofologi, Eugenia Toki
All Works
Highlights What are the main findings? What is the implication of the main finding?Highlights What are the main findings? What is the implication of the main finding?Abstract Background/Objectives: This systematic review examines psychological interventions for children with neurodevelopmental disabilities within a neurodiversity framework, emphasizing that variations in cognition, behavior, and neurological functioning represent natural forms of human diversity rather than deficits. Methods: A systematic literature search was conducted across the PubMed, PsycINFO, and Google Scholar databases for studies published between 2010 and 2025. Studies were included if they focused on children with autism spectrum disorder (ASD), learning or intellectual disabilities …
Race And Ethnicity And Overall Survival In Pediatric Acute Myeloid Leukemia, Daniel J. Zheng, Long Khuong, Catherine Aftandilian, Kira Bona, Emi H. Caywood, Caitlin W. Elgarten, Brian T. Fisher, Cody-Aaron L. Gathers, Taumoha Ghosh, M. Monica Gramatges, Gary Hettinger, Meret R. Henry, Yuan-Shung V Huang, Yimei Li, Kelly Maloney, Amir Mian, Tamara P Miller, Arunkumar Modi, Rajen Mody, Regina M. Myers, Haley Newman, Jose Ortiz, Alix E. Seif, Caroline Smith, Jamie Stokke, Naomi Winick, Jennifer J. Wilkes, Victor Wong, Richard Aplenc, Kelly D. Getz
Race And Ethnicity And Overall Survival In Pediatric Acute Myeloid Leukemia, Daniel J. Zheng, Long Khuong, Catherine Aftandilian, Kira Bona, Emi H. Caywood, Caitlin W. Elgarten, Brian T. Fisher, Cody-Aaron L. Gathers, Taumoha Ghosh, M. Monica Gramatges, Gary Hettinger, Meret R. Henry, Yuan-Shung V Huang, Yimei Li, Kelly Maloney, Amir Mian, Tamara P Miller, Arunkumar Modi, Rajen Mody, Regina M. Myers, Haley Newman, Jose Ortiz, Alix E. Seif, Caroline Smith, Jamie Stokke, Naomi Winick, Jennifer J. Wilkes, Victor Wong, Richard Aplenc, Kelly D. Getz
Department of Pediatrics Faculty Papers
IMPORTANCE: Hispanic and non-Hispanic Black (hereafter, Black) children with acute myeloid leukemia (AML) have historically experienced worse survival outcomes compared with non-Hispanic White (hereafter, White) children. Understanding specific intermediate pathways underlying these outcome disparities is a critical step to directing interventional efforts and resources.
OBJECTIVE: To compare survival outcomes by race and ethnicity in a large contemporary cohort of pediatric patients with AML and to examine presentation acuity, frontline organ toxic effects, and relapse as potential mediators of any observed outcome disparities.
DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study was analyzed from April 2025 to January 2026 and included …
The Fate Of Duplicate Meiotic Recombination Genes After Whole Genome Duplication In Vertebrate And Yeast Lineages, Sophie Maedo
The Fate Of Duplicate Meiotic Recombination Genes After Whole Genome Duplication In Vertebrate And Yeast Lineages, Sophie Maedo
Theses and Dissertations
Meiotic recombination is the exchange of DNA between homologous chromosomes that creates novel allele combinations and therefore aids in evolution. After whole genome duplications (WGD), challenges arise with proper chromosome segregation, necessitating changes to the meiotic recombination pathway. Reducing recombination rate and recombination gene copy number are mechanisms to correct multivalent formation. Within plants, copy number and retention rate of these genes has been well characterized; however, this is untrue for the wider eukaryote domain. Through this work, I show that meiotic recombination genes are maintained at a lower copy number than the rest of the genome; however, immediately after …
Impact Of In-Season Potassium Fertilizer Application On Sweetpotato Yields, Alyssa Lynn Hotchkiss
Impact Of In-Season Potassium Fertilizer Application On Sweetpotato Yields, Alyssa Lynn Hotchkiss
Theses and Dissertations
Sweetpotatoes require approximately three times more potassium (K) than nitrogen (N), making K the most applied nutrient in production. However, K fertilizer recommendations for sweetpotatoes in Mississippi remain outdated or are based on recommendations for other crops. This study evaluated the effects of K fertilizer rate, timing, and application method on sweetpotato production. Field trials were conducted during the 2023 and 2024 growing seasons at the Pontotoc Ridge-Flatwoods Branch Experiment Station in Pontotoc, Mississippi. Treatments included preplant K applications of 0, 134, or 191 kg ha⁻¹ K₂O, in-season sidedress applications of 56 kg ha⁻¹ K₂O, and four foliar K treatments. …