Digital Commons Network^™

Can Hydrolyzed Silk Fibroin Derived From Bombyx Hatayensis And Ozonized Gel Modulate Inflammatory And Angiogenic Responses In A Corneal Alkali Burn Model? ​​, Şule Barman Kaki̇l, Hamdullah Suphi̇ Bayraktar, Okan Soylu, İshak Gökçek, Meryem İlkay Karagül, Zehra Demi̇ray Asoğlu

Turkish Journal of Medical Sciences

Background/aim: The therapeutic effects of hydrolyzed silk fibroin derived from Bombyx hatayensis and a commercially available ozonized gel, administered individually and in combination, were evaluated in a rat model of corneal alkali burn.

Materials and methods: A standardized corneal alkali burn was induced in the right eyes of Wistar albino rats using 1 N sodium hydroxide (NaOH). Animals were randomly assigned to six groups: negative control, positive control (PC), hydrolyzed silk fibroin (SF), ozonized gel (O), combined treatment (SF + O), and antibiotic treatment. Topical treatments were administered for 21 consecutive days. Clinical evaluation included assessments of corneal opacity, neovascularization, …

Repurposing Diclofenac For Combination Therapy: Targeting The Warburg Effect To Enhance Breast Cancer Treatment ​, Gonca Tuna, Eli̇f Ertürk, Ayşen Sağnak, Ferda Ari

Turkish Journal of Medical Sciences

Background/aim: Diclofenac (Diclo), a widely used nonsteroidal antiinflammatory drug, has emerged as a potential candidate for drug repurposing in oncology, with reported anticancer effects extending beyond cyclooxygenase (COX) inhibition, including modulation of tumor metabolism. This study investigated the antiproliferative and glycolysis-associated effects of Diclo in MCF-7 breast cancer cells, alone and in combination with docetaxel (Doc) or 5-fluorouracil (5-FU).

Materials and methods: Cell viability was assessed using the sulforhodamine B (SRB) assay. To evaluate metabolic alterations, glucose uptake and lactate release were quantified following treatment. In addition, Triosephosphate Isomerase (TPI) protein levels and Lactate Dehydrogenase (LDH) activity were measured to …

Antiobesity, Antidiabetic, And Antioxidant Activities Of Selected Rubia Species (Rubiaceae) And Lc–Ms/Ms-Based Chemical Profiling ​, Semi̇h Bulut, Ahmet Kahraman, Ayşenur Işik, Mustafa Abdullah Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Rubia species (Rubiaceae) are recognized as medicinal and industrial plants exhibiting diverse biological activities. This study was conducted to evaluate the antioxidant, antidiabetic, and antiobesity potential of extracts prepared from Rubia davisiana Ehrend. (an endemic species), R. peregrina L., and R. rotundifolia Banks & Sol., which grow naturally in Türkiye.

Materials and methods: The antioxidant activity of 80% ethanol extracts prepared from the aerial parts was evaluated using 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays, ferric reducing power, metal chelating capacity, and total antioxidant capacity assays. Inhibition assays for α-glucosidase and α-amylase were performed to evaluate antidiabetic activity, …

Cervical Conjoined Nerve Root Anomalies: Prevalence And Impact On Posterior Cervical Surgery, Ahmet Eren Seçen, Ayfer Aslan, Musa Onur Özbakir, Uğur Kemal Gündüz, Ali̇ Dalgiç

Turkish Journal of Medical Sciences

Background/aim: Anomalous nerve roots (ANRs) are well described in the lumbosacral spine but are rarely reported in the cervical region. The aim of this study was to evaluate the incidence, clinical characteristics, and surgical outcomes of cervical ANRs, with particular emphasis on conjoined nerve roots, in a single-center clinical series.

Materials and methods: A retrospective analysis was conducted of patients who underwent posterior cervical discectomy for cervical disc herniation at our institution between 2010 and 2025. A total of 113 posterior cervical procedures were performed, and seven patients were found to have surgically confirmed cervical ANRs. For these patients, demographic …

Digital Markers For Passive Remote Monitoring Of Bipolar Disorder: Systematic Review, Thomas P Kutcher, Isha Chakraborty, Kristin Kostick-Quenet, Akane Sano, Nidal Moukaddam, Jeffrey A Herron, Wayne K Goodman, Sameer A Sheth, Ashutosh Sabharwal, Nicole R Provenza

Duncan NRI Faculty and Staff Publications

Background: Bipolar disorder (BD) features episodic shifts among mania, hypomania, depression, mixed states, and euthymia. Timely detection of mood transitions is difficult due to infrequent clinical touchpoints. Digital health technologies, including wearables and smartphones, offer a unique opportunity to passively and continuously monitor behavior and physiology that could reflect underlying mood dynamics in real-world settings.

Objective: This study aimed to systematically review passively collected digital markers for BD mood states, characterize devices/modalities and analytic approaches, appraise risk of bias, and identify design gaps and priorities for clinical translation.

Methods: Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) …

20 Years Of The Kalamazoo Promise: A Visual Guide To Selected Highlights, Kathleen Bolter

Reports

No abstract provided.

Posttraumatic Stress In Newly Diagnosed Epilepsy: Associations With Early Maladaptive Schemas, Anxiety, And Quality Of Life In A 6-Month Prospective Study ​, Mehmet Öztürk, Pinar Öztürk, Fügen Sönmez Çeti̇nkaya, İlker Özdemi̇r

Turkish Journal of Medical Sciences

Background/aim: Epilepsy is a chronic neurological disorder that significantly affects psychosocial functioning, self-perception, and quality of life. Emerging evidence suggests that posttraumatic stress (PTS) symptoms may be more prevalent in individuals with epilepsy than previously recognized, particularly following seizure-related experiences perceived as traumatic. The aim of this study was to evaluate short- and long-term PTS levels in individuals with newly diagnosed epilepsy and examine their associations with anxiety, depression, early maladaptive schemas, and quality of life.

Materials and methods: In this prospective study, 31 individuals with newly diagnosed epilepsy were enrolled. Participants completed a sociodemographic data form, the Post-Traumatic Stress …

Multi-Ion Permeation And Dynamic Conductance Modulation In Connexin Gap Junction Channels, Bassam G. Haddad, Daniel M. Zuckerman, Steve L. Reichow

Chemistry Faculty Publications and Presentations

Gap junction channels formed by connexins mediate direct intercellular communication and are essential for electrical signaling and tissue homeostasis. Despite their large, solvent-accessible pores, connexin channels exhibit distinct conductance, selectivity, and rectification properties, but the molecular mechanisms underlying these behaviors remain incompletely understood. Here, we performed ~67 μs of all-atom computational electrophysiology simulations of connexin-46 (Cx46), connexin-50 (Cx50), and heterotypic Cx46/50 gap junction channels based on high-resolution open-state structures, enabling characterization of both ion permeation and long-timescale channel dynamics. Simulations reveal a multi-ion, multi-pathway permeation mechanism governed by isoform-specific energetic barriers and transient ion coordination sites that shape conductance and …

Scattering Phase Shift In Quantum Mechanics On Quantum Computers: Non-Hermitian Systems And Imaginary-Time Simulations, Peng Guo, Paul Levan, Frank Lee, Yong Zhao

Research & Publications

To overcome the fast oscillatory behavior of correlation functions for extracting scattering phase shift in real-time quantum simulations encountered in the work of Guo et al. [Phys. Rev. D 113, 054512 (2026)], we propose and test two solutions in the present work. One is to simulate Hermitian systems in imaginary time, and the other is to simulate non-Hermitian systems in real time. We demonstrate that both approaches lead to the problem of nonunitary quantum evolution that can be solved by combining two quantum algorithms: block encoding and Hadamard test. The combined quantum algorithm does not require midcircuit …

The Current - Volume 37 Issue 01, Nova Southeastern University

Student Newspapers

No abstract provided.

Conservation As A Guise: Green Grabbing And The Acculturation Erasure In Rempang, Indonesia, Umi Ma'rufah, Bobi Bobi, Yogi Eka Sahputra, Muhammad Ishlahudin

Forest and Society

This study examines how the state enacts green grabbing through forestry legal instruments and how this process intersects with the existence and cultural acculturation of the Sungai Raya community. Previous studies on state-led green grabbing have predominantly emphasized economic, political, and ecological dimensions, often overlooking the socio-cultural dynamics of affected communities. Employing a qualitative narrative research approach, this study draws on in-depth interviews and literature review to reconstruct the life histories of community members. Using the Rempang Eco-City National Strategic Project as a case study, this research identifies the unilateral designation of Kawasan Hutan Taman Buru (the Hunting Park Forest …

Ancestors And Tiger From Elsewhere: Emerging Forms Of Human-Tiger Socio-Natural Relations In Cosmopolitical Frontiers Of Sumatra, Imam Ardhianto, Febri Sastiviani Putri Cantika, Matahari Jingga, Dimas Iqbal Romadhon

Forest and Society

How are the moral relations between communities and the Sumatran tiger (Panthera tigris sumatrae) being reconfigured as forests fragment and land-use change accelerates across Sumatra's conservation landscape? This article addresses that question ethnographically, drawing on forty semi-structured interviews conducted in Agam and Pasaman Regencies (West Sumatra) between April and June 2026 and interviews with Yayasan SINTAS Indonesia. The article documents the three animistic category of the tiger, comprising Datuk/ancestor, harimau jadi-jadian, and harimau tandang, and traces how it is being reshaped by habitat fragmentation, commodity-driven land expansion, generational interruption of customary authority, and state translocation …

Unpacking System Factors Contributing To Delayed Icu Discharges: A Mixed-Method Study, Xia Jin, Anne Mette Nørby Adams, Joanne Mcintyre, Steven Galluccio, Shailesh Bihari, Ubbo F. Wiersema, Kathrine De Lyster, Frances Fengzhi Lin

International Nursing Research Congress (INRC)

Background: Discharge delay in resource-constrained Intensive Care Units (ICUs) remains a concerning and persistent challenge, resulting in delayed ICU admissions and after-hours discharges. These delays are associated with adverse patient outcomes and system inefficiency. While centralised patient flow centres and other strategies have been implemented to address these issues, their impact on ICU discharge delays remains unexplored. To improve patient flow, it is essential to explore organisational barriers and facilitators to ICU discharge.

Objective: To identify system factors influencing ICU discharge in a tertiary Australian hospital.

Methods: A mixed-method study was conducted in a 32-bed tertiary ICU in Australia. Between …

The Freedom Myth: How Ski Culture's Hidden Conformity Reveals The Unconscious Power Of Brand Belonging, Isabel R. Phillips

University Honors Theses

Purpose: Ski culture sells freedom and enforces conformity. This review asks what unconscious behavioral patterns hold that contradiction in place, and how brands capitalize on it to manufacture belonging.

Design/Methodology/Approach: A narrative literature review across consumer psychology, behavioral neuroscience, sociology, and ski industry research. No primary data were collected. Four accounts of consistency-seeking are synthesized into one framework, then applied to three ski industry cases at ascending scales and tested against a comparative case from Spanish football.

Findings: Belonging is a conditioned response, and conditioning requires a stable stimulus. Consistency is therefore the precondition of belonging rather than a constraint …

Motherhood-Defining Memories And Narrative Identity Awareness In Relation To Psychological Wellbeing And Maternal Functioning Following A Parenting Program, Christin Camia, Antje Von Suchodoletz, Michelle P. Kelly

All Works

Introduction – Drawing on previous research showing that self- and relationship-defining memories relate to psychological and relational functioning, this study began to explore motherhood-defining memories and their relation to psychological wellbeing and maternal functioning within a parenting program context. The study aimed to examine whether participation contributes to the narrative coherence of motherhood-defining memories. Methods – Participants were 155 mothers from diverse cultural backgrounds (M age = 32.85 years, SD age = 5.20) residing in the United Arab Emirates (UAE). Seventy-five mothers participated in an eight-session parenting program, and 80 mothers served as controls in a comparison group. Motherhood-defining memories …

Definitive Radiation Therapy For Schneiderian Inverted Papilloma Of The Soft Palate And Uvula., Rahul Sinha, Arianne J Abreu, Christopher E Fundakowski, Robert T Sataloff

Otolaryngology (ENT) Resident Research

Schneiderian inverted papilloma is a benign, locally aggressive tumor that typically arises in the respiratory mucosa of the nasal cavity and paranasal sinuses. These tumors are often asymptomatic but can cause unilateral nasal obstruction, discharge, hyposmia and epistaxis. They warrant attention particularly due to the potential for malignant transformation. They are treated most often with surgical excision. This case report describes a patient with Schneiderian inverted papilloma arising outside its usual location and managed with definitive radiation therapy instead of surgical excision due to concerns for functional impairment. Remission was obtained with radiation therapy, although the patient experienced treatment-related side …

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.

Crispr-Cas9: An Emerging And Precise Genome Editing System For Crops To Combat Food Insecurity, Muhammad Faran Tahi̇r, Muhammad Hamzah Saleem, Sidra Aslam, Emi̇ne Orhan, Hayat Topçu, Tauqeer Ahmed Qadri, Khalid Ali Khan, Muhammad Anas

Turkish Journal of Agriculture and Forestry

Genome editing has emerged as a transformative tool to improve crop productivity, resilience, and nutritional quality, helping address global food insecurity. Among gene-editing platforms, clustered regularly interspaced short palindromic repeats (CRISPR)/ Cas systems (notably CRISPR-Cas9) offer simple, efficient, and scalable methods for targeted modifications, including knockouts, base edits, and precise “search-and-replace” prime edits. In plants, recent advances such as improved base editors, optimized prime-editing platforms, and DNA-free delivery methods have expanded the scope of edits achievable while reducing off-target effects and regulatory concerns. This review summarizes CRISPR principles, highlights technical breakthroughs and crop applications that mitigate biotic and abiotic stresses, …

Cultivar, Canopy Architecture, And Harvest Stage Shape The Chemical Profile Of Plum (Prunus Domestica) Fruit, Jelisaveta Seka Cvijanović, Milica Sredojević, Dragana Dabić Zagorac, Maja Natić, Geza Bujdoso, Miljan Cvetković

Turkish Journal of Agriculture and Forestry

Plum (Prunus domestica L.) is a nutritionally valuable fruit with significant commercial importance, yet consumer acceptance is often constrained by inconsistent fruit quality. This study investigated the effects of cultivar, training system, and harvest stage on the chemical composition of plum fruit, focusing on polyphenols, organic acids, sugars, and sugar alcohols. Three cultivars (Čačanska lepotica, Stanley, and Empress) were evaluated under different canopy architectures, including plum spindle as a control and novel 2-dimensional systems (Bi axe and upright fruiting offshoot), across multiple ripening stages. The results showed that genotype and canopy structure significantly influenced the accumulation of primary and secondary …

Beyond Closed Doors: Standardizing Intimate Partner Violence Screening In A Predominantly Spanish-Speaking Primary Care Clinic, Sarah Abughrib

Master's Projects and Capstones

Objective: Intimate partner violence is a widespread public health concern, with an estimated 64.2 million U.S. adults affected in their lifetime and significant physical, psychological, and economic consequences. Due to systemic challenges, IPV screening remained inconsistent across an adult primary care clinic serving a predominantly monolingual Spanish-speaking population in the San Francisco Bay Area, with only 4.1% of patients screened across the Adult, Women's, and Teen clinics in June 2026. Aim: This quality improvement project aimed to increase overall IPV screening by 10%, from 4.1% to 14.1%, by July 31, 2026. Methods: Standardization efforts included introducing a …

Teachers’ Communicative Experiences Of Media And Information Literacy (Mil) In Peri-Urban Schools In The Southern Philippines: A Hermeneutic Phenomenological Analysis, Author Information Removed

JMLE Submissions Open for Review

Media and Information Literacy (MIL) has become increasingly important as education responds to an increasingly complex information environment, yet less is known about how teachers experience and make sense of teaching it, particularly in resource-constrained contexts. Guided by Gadamerian hermeneutic phenomenology, this study explored the lived communicative experiences of seven Senior High School teachers from five peri-urban public schools in the Southern Philippines. In-depth interviews revealed three interconnected, culturally situated meanings: pagsugakod (carrying on amid uncertainty), pagtagad (attentive responsibility), and pagkabalaka (ongoing concern). Together, these meanings show how teachers navigate limited preparation, respond to students’ lived circumstances, and teach within …

A Dosimetric Comparison Of 6-Mv Flattening Filter And Flattening Filter-Free Photon Beams For Stereotactic Body Radiation Therapy Of Adrenal Tumors, Sarah Mcintosh

Masters Projects

Purpose: This study aimed to compare dosimetric characteristics and treatment delivery efficiency between 6-MV Flattening Filter (FF) and Flattening Filter-Free (FFF) photon beams for adrenal Stereotactic Body Radiation Therapy (SBRT). While FFF beams have demonstrated dosimetric and efficiency advantages at other SBRT sites, there is limited data about their use in adrenal SBRT.

Methods and Materials: A retrospective dosimetric comparison was performed using 10 patients previously treated with adrenal SBRT. For each patient, two Volumetric Modulated Arc Therapy (VMAT) plans were generated in Eclipse: one using 6-MV FF beams and one using 6-MV FFF beams, resulting in 20 total treatment …

Staff Education On Fall Reduction For Residents Of Long-Term Care Facility, Lauretta Ifeoma Iwuala-Mcwilliams

Walden Dissertations and Doctoral Studies

Falls pose a major safety risk for elderly individuals living in long-term care facilities, leading to injuries, hospitalizations, loss of autonomy, increased healthcare expenses, and higher morbidity and mortality rates. In the facility involved in this project, the incidence of falls was above anticipated benchmarks. Factors such as high staff turnover and reliance on agency staff resulted in inconsistent knowledge among personnel regarding fall prevention measures. Purpose: This Doctor of Nursing Practice quality improvement initiative aimed to implement and assess an evidence-based educational program designed to enhance staff understanding and skills related to fall-risk assessment, the identification of both intrinsic …

Creating Consistency: Standardizing Gestational Diabetes Group Visit Framework In High-Risk Obstetric Care, Danielle Pack

Master's Projects and Capstones

Objective: Gestational diabetes mellitus (GDM) requires timely and consistent education to promote effective self-management and improve maternal and fetal outcomes. Baseline observations at a Santa Clara County high-risk obstetric clinic identified variation in educational materials, educator delivery, referral processes, and workflows between English- and Spanish-language GDM group visits. A review of the literature supported standardized diabetes education and group prenatal care as strategies to improve consistency, efficiency, and patient access. Aim: This quality improvement project aimed to develop and implement a standardized GDM group visit framework for nurse practitioners, registered dietitians, and scheduling staff, with the goal of increasing compliance …

You Haven’T Been Forgotten: Driving Improvements In Trust, Transparency, And Accountability Through A Patient-Centered Communication Initiative In The Emergency Department, Ellie Mead

Master's Projects and Capstones

Objective: In Spring 2026, the Emergency Department (ED) at Hospital X identified difficulties securing high levels of patient satisfaction. Over one third of patients did not feel adequately “informed about delays,” and observation of nurse-patient interactions in front-end care areas confirmed these communication gaps: in 87% of interactions, nurses did not explain next steps to the patient, and in none of the 51 interactions observed did nurses proactively inform patients about possible delays. Aim: This quality improvement initiative sought to improve the patient experience in the ED and drive a 10% increase in Press Ganey patient satisfaction survey results relating …

Cover And Contents

Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

Treaty Hierarchy And Legal Pluralism In Cross-Border Governance: Comparative Study Of Jordan And France, Rola Nael Salameh, Numan Ahmad Elkhatib, Rami Ali Daradkeh, Mohammad Sulieman Issa Alhelalat

Hasanuddin Law Review

This study addresses the constitutional ambiguity surrounding the hierarchical status and domestic application of international human rights treaties, particularly in legal systems where treaty incorporation lacks explicit constitutional regulation. Though earlier researches have discussed issues such as treaty incorporation and constitutionality, there has been little analysis of the comparative role played by courts in bridging the international and domestic legal systems. The study adopts a qualitative doctrinal and comparative legal methodology, analyzing constitutional provisions, legislative frameworks, and judicial decisions across Jordan, France, and selected Arab jurisdictions, including Egypt and Morocco. The findings reveal that France adopts a hierarchical model granting …

Judicial Departure And Legal Certainty: A Comparative Study Of Us And French Law, Faisal Oklah Khattar Shatnawi, Abdulwahab Abdullah Al-Maamari, Yassin Ahmad Al-Qudah, Radeyah Ahmad Mohammad Amayreh, Muneer Ali Muhammad Hulaiel

Hasanuddin Law Review

In any constitutional system, it is difficult to reconcile the need for legal certainty and constitutional adaptation when there is judicial departure from constitutional precedent. In this paper, We develop a functional comparative approach that explains how constitutional systems maintain legal certainty in the face of constitutional adaptation enabled by judicial departure from constitutional precedents. Using comparative analysis of United States Supreme Court jurisprudence (1954–2023) and French Constitutional Council rulings (1971–2023), We examine how such systems preserve their constitutional stability in spite of judicial change. It is concluded that the departure of courts from constitutional precedent need not mean the …

Governing Conservation Beyond The Rules: Bureaucratic Discretion In Indonesia, Dedy Asriady, Muh. Ilham Nasir, Emban Ibnurusyd Mas'ud, Supratman Supratman, Syamsu Alam, Muhammad Alif K. Sahide

Hasanuddin Law Review

Conservation governance is frequently characterized as a rule-based system in which bureaucratic actors enforce standardized regulations to protect biodiversity. In practice, however, conservation policies are implemented within socially contested landscapes. Strict regulatory enforcement may generate conflict and undermine governance objectives. Although public administration research underscores the importance of bureaucratic discretion in policy implementation, limited attention has been paid to its influence on environmental governance in developing countries. This article investigates discretionary practices in Indonesian conservation area management using an ethnographic approach that incorporates interviews, field observations, and case studies across multiple sites. The findings demonstrate that discretion occupies a central, …

Topology-Aware Graph Neural Network With Spatiotemporal Encoding And Contrastive Learning For Scalable Dynamic Network Representation, Wassan S. Hayale, Rasha S. Ali, Raghda Abd Ul Rab Abd Ul Hasan, Lateef Abd Zaid Qudr, Safwan Nadwe, Nitin S. Solke, Ravi Sekhar, Pritesh Shah, Reyad Omran Essa

Mesopotamian Journal of Big Data

Recently, Dynamic Graph Neural Networks (DGNNs) have become a potent candidate to model time-changing graphs, although other solutions, including Temporal Graph Networks (TGN), Evolving Graph Convolutional Networks (EvolveGCN), and Dynamic Self-Attention Networks (DySAT), still have significant barriers to scalability, computational efficiency, and temporal embedding drift. To overcome these drawbacks, this paper presents a Topology-Aware Graph Neural Network (TAGNN) model capable of incorporating graph-topology encoding and the spatiotemporal memory mechanisms into the learning process of dynamic node representation. The proposed framework includes three key components: (i) returns global and local structural data such as graph Laplacian-based feature transformations and position encodings, …