Digital Commons Network^™

The Long Run Effects Of A Teacher-Focused School Reform On Student Outcomes, Sarah R. Cohodes, Ozkan Eren, Orgul Ozturk

Faculty Publications

This paper examines the effects of a teacher-focused school reform program — combining performance pay with teacher observation and feedback — implemented in high-need schools on students’ longer-run educational, criminal justice, and economic self-sufficiency outcomes. Using linked administrative data from a Southern state, we leverage the quasi-randomness of the timing of program adoption across schools to show that the school reform improved educational attainment and reduced both felony criminal activity before age 19 and dependence on government assistance in early adulthood (ages 18–22). We find little scope for student sorting or changes in the composition of teacher workforce to explain …

Nitric Oxide Required For Transition To Slower Hepatic Protein Synthesis Rates During Long-Term Caloric Restriction, Hector H. Palacios, Edward Cao, Adelaide Cahill, Hussein Mohamad, Marc K. Hellerstein

2020-Current year OA Pubs

Calorie restriction (CR) extends maximal lifespan and maintains cellular homeostasis in various animal models. We have previously shown that CR induces a global reduction of protein fractional synthesis rates (FSRs) across the hepatic proteome in mice, but the timing and regulatory mechanisms remain unclear. Nitric oxide (NO), a bioactive molecule upregulated during CR, is a potential regulator of protein synthesis. To explore the role of NO in hepatic proteome fluxes during CR, we used in vivo deuterium labeling from heavy water and liquid chromatography/mass spectrometry-based (LC/MS-based) flux proteomics in WT and NO-deficient (NO-) mice. We observed a transition to reduced …

Reported Safety Practices Of Publicly Advertised Psychedelic Retreats, Amy L Mcguire, Logan Neitzke-Spruill, Jill O Robinson, Caroline S Beit, Nikita Singh, David S Mathai, Lynnette A Averill

Center for Medical Ethics and Health Policy Staff Publications

Importance: The availability of psychedelic retreats has grown to meet the demand for access to these substances. Despite centuries of use among Indigenous communities, psychedelics can pose serious risks for some users.

Objective: To determine safety precautions that retreat organizations that offer psychedelic substances currently use.

Design, setting, and participants: This qualitative study included structured interviews conducted by phone or email with representatives from 49 organizations publicly advertising psychedelic retreat offerings from July to October 2023. Organizations were eligible if they marketed their services in English, offered at least 1 psychedelic substance, and made contact information available online. Organizations were …

Continuous Learning And Customer Value Creation In The Healthcare: Mediating Effects Of Innovations Adoption Value Recognition, Binto M. Binto, Omari Khalifa Mbura

Business Management Review

This research investigates the influence of continuous learning on the effectiveness of customer value creation in the Tanzania’s healthcare system, with a specific focus on the mediating effects of innovation adoption value recognition. Using a cross-sectional design, data were collected from 360 healthcare professionals across three zonal referral hospitals in Tanzania. Data analysis employed a structural equation modelling using SMART-Partial Least Squares software version 4.0. The findings indicate that continuous learning enhances healthcare customer value creation both directly and indirectly. Also, innovation adoption value recognition serves as a mediating variable of the direct causal relationship, offering partial mediation effects between …

Dual Challenges, Shared Wins: Unlocking Climate Financing For Nutrition, Chiara Dell’Aira, Natalia Rovelo-Velazquez, Sarah Lahaye, Xiu Xin Catherine Lok, Stella Nordhagen, Stephen Dorey, Mireya Vilar-Compte

Department of Public Health Scholarship and Creative Works

Background

The intertwined challenges of climate change and malnutrition amplify each other, with climate change exacerbating malnutrition, particularly in vulnerable populations; and food systems significantly contributing to emissions and environmental degradation. Addressing these issues together offers opportunities for shared gains, yet funding streams for these sectors remain siloed and misaligned.

Objective

This study developed a scoring methodology to assess the compatibility of climate funds with financing nutrition-related actions where synergies align with climate funds’ primary goals, referred to as the “scope for nutrition integration”.

Methods

Using the Climate Funds Update database, 18 active climate funds were systematically reviewed …

Making Waves Through Expedition, Jenna Malloy, Natalia López-Figueroa, Ana Arellano

Making Waves REU

No abstract provided.

Nf2 Loss Malignantly Transforms Human Pancreatic Acinar Cells And Enhances Cell Fitness Under Environmental Stress, Yi Xu, Michael H Nipper, Angel A Dominguez, Chenhui He, Francis E Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang

Faculty, Staff and Student Publications

Pancreatic ductal adenocarcinoma (PDAC) occurs as a complex, multifaceted event driven by the interplay of tumor-permissive genetic mutations, the nature of the cellular origin, and microenvironmental stress. In this study, using primary human pancreatic acinar 3D organoids, we performed a CRISPR-KO screen targeting 199 potential tumor suppressors curated from clinical PDAC samples. Our data revealed significant enrichment of a list of candidate genes, with neurofibromatosis type 2 associated gene (NF2) emerging as the top target. Functional validation confirmed that loss of NF2 promoted the transition of PDAC to an invasive state, potentially through extracellular matrix modulation. NF2 inactivation …

Peroxisomal Integrity In Demyelination-Associated Microglia Enables Cellular Debris Clearance And Myelin Renewal In Mice, Joseph A Barnes-Vélez, Xiaohong Zhang, Yaren L Peña Señeriz, Kiersten A Scott, Yinglu Guan, Jian Hu

Faculty, Staff and Student Publications

Demyelination associated microglia (DMAM) orchestrate the regenerative response to demyelination by clearing myelin debris and promoting oligodendrocyte maturation. Peroxisomal metabolism has emerged as a candidate regulator of DMAMs, though the cell-intrinsic contribution in microglia remains undefined. Here we elucidate the role of peroxisome integrity in DMAMs, using cuprizone-mediated demyelination coupled with conditional KO of peroxisome biogenesis factor 5 (PEX5) in microglia. Absent demyelination, PEX5 conditional KO (PEX5cKO) had minimal impact on homeostatic microglia. However, during cuprizone-induced demyelination, the emergence of DMAMs unmasked a critical requirement for peroxisome integrity. At peak demyelination, PEX5cKO DMAMs exhibited increased lipid droplet burden and reduced …

Cholesterol Efflux Protein, Abca1, Supports Anticancer Functions Of Myeloid Immune Cells, Shruti V Bendre, Yu Wang, Basel Hajyousif, Rajendra K C, Shounak G Bhogale, Dhanya Pradeep, Natalia Krawczynska, Claire P Schane, Erin Weisser, Avni Singh, Simon Han, Hannah Kim, Lara Kockaya, Anasuya Das Gupta, Adam T Nelczyk, Hashni Epa Vidana Gamage, Yifan Fei, Desirée Rodríguez-Casiano, Xingyu Guo, Haoyun Li, Ryan J Deaton, Fei Mo, Maria Sverdlov, Peter H Gann, Saurabh Sinha, Sahil Sahni, Kun Wang, Kevin Van Bortle, Emad Tajkorshid, Wendy A Woodward, Wonhwa Cho, Erik R Nelson

Faculty, Staff and Student Publications

Breast and other solid tumors respond poorly to immune therapy. Myeloid cells (MCs) such as macrophages contribute to resistance. Established clinical evidence links cholesterol to cancer outcomes, with MC function being regulated by cholesterol metabolism. We screened MC-expressed regulators of cholesterol homeostasis linked to survival and identified the cholesterol efflux protein ABCA1. ABCA1 activity increases anticancer functions of macrophages: enhancing tumor infiltration, decreasing angiogenic potential, reducing efferocytosis, and improving support of CD8+ T cell activity. Mechanistically, different AKT isoforms are involved, through both PI3K-dependent and PI3K-independent mechanisms. Highlighting the clinical relevance of our findings are correlations between ABCA1 in macrophages …

Etoposide-Associated Severe Rhabdomyolysis In A Patient With Diffuse Large B-Cell Lymphoma: A Case Report And Review Of The Literature, Ibrahim Al Nabhani, Ruquiya Al Dhuhli, Farah Al Kindy, Mahmood Al Abri, Khalil Al Farsi, Almundher Al Oraimi

Sultan Qaboos University Medical Journal

Rhabdomyolysis is a clinical syndrome characterised by skeletal muscle necrosis with subsequent release of intracellular constituents into the circulation. Although multifactorial in aetiology, chemotherapeutic agents, including etoposide, are rarely implicated. We report a 62-year-old male who presented to a tertiary care hospital in Muscat, Oman, in 2023 with severe rhabdomyolysis and advanced-stage diffuse large B-cell lymphoma following the first cycle of R-CEOP chemotherapy. Extensive evaluation excluded infectious, inflammatory and structural neuromuscular aetiologies. Work-up for metabolic myopathy suggested, but did not confirm, multiple acyl-CoA dehydrogenase deficiency. The patient’s clinical course was complicated by acute kidney injury necessitating dialysis, followed by gradual …

Person-Centered Care In Adult Auditory Rehabilitation: A Scoping Review, Marien Alet Graham, Nannette Nicholson, Rachel Glade, Sonja Delport, Faheema Mahomed-Asmail

Communication Disorders and Occupational Therapy Faculty Publications and Presentations

Objective To scrutinise the efficacy of person-centered care (PCC) in enhancing outcomes for adults navigating hearing loss through a comprehensive examination of literature on PCC in auditory rehabilitation (AR). Design A scoping review was conducted following Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) reporting standards. A context framework guided the research question. Study Sample Structured searches across multiple databases identified 36 records which were categorised by research design, mapped by the first author's country, and depicted by number of publications per year. Six identified elements of PCC were anaylzed …

Circadian-Shaped Immune Variability Predicts Infection Outcome, Jonathan Lalsiamthara, Mariko Locke, Alejandro Aballay

Faculty, Staff and Student Publications

Disease risk and severity are influenced by genetics, epigenetics, and environmental factors. However, immune responses vary even among genetically similar or related individuals, shaped by inherited and noninherited factors. Using Caenorhabditis elegans, we found that pathogen susceptibility can be predicted by preinfection biomarkers. Individuals with high-basal expression of irg-5, an infection response gene regulated by the p38 mitogen-activated protein kinase-1 (PMK-1) pathway, were more susceptible to Pseudomonas aeruginosa infection. A genome-wide screen identified the myeloid ecotropic viral integration site-1 (MEIS) homeobox protein UNC-62 as a regulator of irg-5 expression, acting through PMK-1 and GATA binding erythroid-like transcription factor …

Impaired Complement Regulation Drives Chronic Lung Allograft Dysfunction After Lung Transplantation, Hrishikesh S. Kulkarni, Laneshia K. Tague, Fuyi Liao, Zhiyi Liu, Lorena Garnica, Nishanth R. Shankar, Xiaobo Wu, Dequan Zhou, Yan Tao, Victoria E. Davis, Cory T. Bernardt, Derek E. Byers, Chad A. Witt, Daniel Kreisel, John P. Atkinson, Andrew E. Gelman, Et Al.

2020-Current year OA Pubs

A greater understanding of chronic lung allograft dysfunction (CLAD) pathobiology, the primary cause of death after lung transplantation (LTx), is needed to improve outcomes. The complement system links innate to adaptive immune responses and is activated early after lung transplantation to form C3 convertase, a critical enzyme that cleaves the central complement component C3. We hypothesized that LTx recipients with a genetic predisposition to enhanced complement activation have worse CLAD-free survival mediated through increased adaptive alloimmunity. We interrogated a known functional C3 polymorphism (C3 R102G) that increases complement activation through impaired C3 convertase inactivation in 2 independent LTx recipient cohorts. …

Upcycle Of Used Jute Sacks For Production Of Shoes And Bags As Fashion Accessories, Solomon Gausa Dr., Ruth Adumna Ahmed, Muhammad Sani Yahaya Dr., Dymphna Bakker-Edoh Dr

Jurnal Sosial Humaniora Terapan

The study aims to upcycle used jute sacks into fashion accessories for sub-Saharan Africa, particularly Nigeria. The approach employs innovative design techniques and manufacturing processes that improve both the aesthetic appeal and environmental impact of jute products. To achieve the study's objectives, a design and development research approach was used to support an iterative process. A structured interview guide collected data from fifteen respondents. The study used thematic analysis by coding both open and axial codes, which were selected and grouped according to the objective to reach the final results before interpreting and translating the findings into a developed design …

Nasionalisme Di Era Artificial Intelligence: Scoping Review, Mudita Vidyananda, Angelina Regina Halim, Patricia Irene, Muhammad Firliansyah Maliki, Ivana Suryaprawira, Bonar Hutapea

Jurnal Sosial Humaniora Terapan

This paper aims to map and thematically present the existing literature on the intersection of Artificial Intelligence (AI), identity, and AI Nationalism, following a scoping review approach. A systematic search was conducted across the Scopus, Web of Science, ACM Digital Library, and Google Scholar databases to identify relevant studies. The selected studies, published between 2020-2025, focus on the impact of AI on identity and geopolitics, resulting in six papers included in the final synthesis. The analyzed studies employed various methods, including conceptual, qualitative, quantitative, and mixed-methods approaches. Data extracted from each study included author, publication year, objectives, methodology, and key …

Pengujian High Fidelity Prototipe Media Pembelajaran Interaktif Bahasa Inggris Dengan Gamifikasi Menggunakan User Experience Questionare, Adhitya Prastyadi, Meizano Muhammad Ardhi, Daniel Rinaldi, Margaretha Karolina Sagala

Jurnal Sosial Humaniora Terapan

Abstract

Testing a Hi-Fi Prototype of Interactive English Learning Media with Gamification Using UEQ

This study aims to test and evaluate the User Experience (UX) quality of a High-Fidelity prototype for interactive English learning media integrating gamification elements. The research is motivated by the low English proficiency and motivation among Indonesian students, and the potential of digital media and gamification to enhance learning engagement. Inspired by the success of the Duolingo application, this prototype was designed to create an enjoyable and effective learning experience. A quantitative research methodology was employed, involving high school students as participants selected via purposive sampling. …

When You Can't Get A One-Shot, Try A One Off, Chereeka Garner, Katy Miller, Renee Cole Montgomery

Georgia International Conference on Information Literacy

One of the challenges facing librarians is getting exposure to students to teach information literacy skills. Faculty engagement with the library can vary greatly, with many faculty simply not having available class time to allow librarians in the classroom. As a possible alternative means of connecting with students, an Extra Credit Hub was created. This hub is an easily located, visible resource for faculty to share potential extra credit activities with students.

The Hub, which is a standalone Canvas course, includes a number of activities related to key information literacy skills, such as:

• Recognizing bias, misinformation, and disinformation
• Critical thinking …

The Gsa Leadership Committee: Collective Liberation Through Community Building In Chicago Public Schools, Elizabeth A. Jarpe-Ratner, Corey M. Blake, Emilie L. Clark, Li Lichner, Meaghan L. Tomasiewicz, Nora Benomar, Jose Dominguez Magdaleno, Booker Marshall, Makayla Boyd, D. Little

Journal of Queer and Trans Studies in Education

Strong evidence links Gender and Sexuality Alliances (GSAs) to improved outcomes for LGBTQ+ (lesbian, gay, bisexual, queer and questioning and other identities) students. Chicago Public Schools’ (CPS) is known for being a leader in supporting LGBTQ+ students. Despite this, CPS’ size has made it difficult to support all schools in adopting recommended practices. Therefore, in 2020 CPS launched the GSA Leadership Committee (GSALC), which comprises teachers and other school-based staff leaders throughout the district, to support all schools in adopting practices known to support LGBTQ+ students. This paper draws on four years of interviews with group facilitators and focus groups …

Exploring The Role Of Occupational Therapy In The Delivery Of Trauma-Informed Services To Hospital-Based Clients Ot, Frank Czuba

Journal of Applied Disciplines

Hospitalization can traumatize clients and impact overall health outcomes, leading to increased hospital readmission rates and resulting in a negative impact for both clients and providers. Limited information exists regarding how hospital-based occupational therapists evaluate and address trauma, even though incorporating trauma-informed principles into professional practice can enhance the occupational therapy process. The study explored the comprehension and perceived significance of trauma-informed tenets among occupational therapists delivering services in hospital-based settings. A quantitative research study with an exploratory design was implemented to explore how occupational therapists (OT) understand and utilize trauma-informed practices with their clients in a hospital setting. An …

The Impact Of Natural Cavities On Mining Feasibility In Brazil: Dilemma Between The Sustainability Of Mining Operations And The Environment, Tiago Leite, Felipe Souza, Mariana Silva, Iuri Brandi, Hernani De Lima

Journal of Sustainable Mining

Due to the legislation on natural underground cavities in Brazil, mineral reserves have been blocked, causing a great dilemma between the sustainability of the mineral activity and the preservation of cavities. This study presented an analysis of the evolution of the federal cave legislation, pointing out the main gains and contribution to the theme, in which the importance in the Brazilian scenario of the publication in 2017 of Normative Instruction N° 01, which updated the procedures for the definition of these “other forms of compensation” to the irreversible negative impact on cavities with a high degree of relevance. In this …

Multivariate Stochastic Mine Scheduling Targeting Stationary Grades Considering Risk Uncertainty And Hierarchical Variables, Augusto A. T. Toledo, Joao F. C. L. Costa, Diego M. Marques, Luciano N. Capponi

Journal of Sustainable Mining

In short-term mine planning for deposits characterized by multiple variables, sequential diglines are generated with an emphasis on maintaining consistent grade distributions across mining periods. This research integrates an array of mineral variables, including deleterious elements, to facilitate the establishment of excavation geometries that enable precise grade and volume control within operational production zones. Through the systematic application of geostatistical analysis coupled with process optimization, geological risks associated with grade uncertainties are minimized, and an optimized operational sequence for the extraction of mineral blocks is pursued. The main point of this approach is maintaining grade distributions aligned with the historical …

An Innovative Implicit Modeling Technique To 3d Deposit Modeling: A Case Study Of The Chromite Mine, Ali Can Ozdemir Ozdemir, Yavuz Tore

Journal of Sustainable Mining

The location of an orebody known to show regional variability in space is determined only through 3D geological modeling. A reliable 3D orebody model must be obtained to ensure resource efficiency and sustainability in the mining industry. In addition, 3D geological modeling has become indispensable in intelligent mining, smart mining, and mining 4.0. In previous years, explicit methods were widely used for 3D geological modeling. However, the validity of geological models produced with these methods has been debated. It has been understood that they are inadequate in modeling vein-type mineralizations with complex geometry in particular. For this reason, implicit modeling …

A Review Study Of The Relationship Between Coal Fly Ash Characteristics And The Presence Of Rare Earth Metals From Steam Power Plants In Indonesia, Muhammad F. Shafiyurrahman, Shofa Rijalul Haq, Nurkhamim Nurkhamim, Ade Kurniawan, Rofa D Bulopa, Rizki Khoiriah Nasution

Journal of Sustainable Mining

The establishment of a coal mining downstream ecosystem focused on a sustainable and environmentally friendly economy is an important goal for many countries. One strategic step in achieving this goal is the utilization of coal fly ash (CFA) waste as a secondary source of rare earth elements (REE). The use of CFA provides a solution to the environmental and health challenges resulting from mining primary sources. Prior to developing REE extraction technology, CFA characterization must be conducted. Therefore, this study addresses the relationship between CFA characteristics and the presence of REE. Based on the ASTM C618-12 standard, CFA in Indonesia …

Integrated Optimization Of Underground Mine Ventilation Using Hardy Cross, Monte Carlo Simulations, And Machine Learning Techniques: A Step Toward Sustainable Mining, Hussein A. Saleem

Journal of Sustainable Mining

Underground mine ventilation is crucial for ensuring worker safety, air quality, and operational efficiency. Effective optimization of ventilation systems reduces energy consumption, enhances airflow distribution, and minimizes risks associated with harmful gases and fire hazards. This study proposed an integrated framework combining the Hardy Cross (HC) method, Monte Carlo (MC) simulations, and machine learning (ML) techniques to optimize the ventilation system at the Jabal Sayid mine in Saudi Arabia. The HC method was employed to provide deterministic baseline airflow calculations, while the MC simulations accounted for uncertainties in resistance values and environmental conditions, generating probabilistic distributions of key parameters. Among …

Study On Visualization Simulation And System Dynamic Optimization Of The Ore Drawing Process In Mine Chutes, Liang Juan, Zhu Quanjie, Hao Yingnan, Quan Zhongxue, Zhang Zhiwu, Liu Xiaohuic, Ouyang Zhihua

Journal of Sustainable Mining

The ore release process in metal mine chutes is a critical part of the mining operation. Based on the urgent demand for intelligent mining construction, this paper proposes a visualization simulation and dynamic optimization method for the mine chute ore release process using the open-source programs Python and Blender. The main research content includes: designing the simulation method and model for the ore release process, including the main control program, process subprograms, etc.; proposing a visualization simulation method for the mine chute ore release process based on Blender, studying the impact of ore shape and size on ore release efficiency, …

Assessment Of Heavy Metal Contamination In Surface Water Near Tailings Dam, Gera Techane Mengistu, Tesema Kebede, Enatfenta Melaku, Engdasew Temere

Journal of Sustainable Mining

Elevated levels of heavy metals in surface water can lead to the degradation of water quality, especially in mining areas where tailing dams are sources of heavy metal pollution. This study focuses on evaluating the concentrations of heavy metals in surface water near the Legadembi tailings dams. The mean concentrations (in µg/L) of various heavy metals including: arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), mercury (Hg), molybdenum (Mo), nickel (Ni), lead (Pb), antimony (Sb), selenium (Se), thallium (Tl), uranium (U), vanadium (V), tungsten (W), zinc (Zn), and zirconium (Zr) were determined: 79.7, 0.15, 162.3, 0.66, 18.1, 0.01, …

Intrinsically Safe Pneumatic Seismic Source For Controlled Rock Mass ,Monitoring And Imaging In Underground Mining, Przemysław Sierodzki, Leszek Remiorz, Mateusz Ćwiękała, Krzysztof Krawiec

Journal of Sustainable Mining

This article explores the technical principles of pneumatic seismic sources, focusing on their application in underground mining operations, including environments prone to fire hazards. It introduces an intrinsically safe pneumatic seismic source as a cost-effective solution for quasi-continuous seismic excitation, useful for detecting stress concentrations in mining settings. These stress concentrations are identified through anomalies in seismic wave velocity, which may indicate potentially hazardous deformations in the rock mass. The developed system enables fully remote operation from the surface and integrates with a seismic monitoring system to capture high-resolution waveforms. The study provides an overview of the pneumatic system’s technical …

Investigating Frozen Paste Surface Disposal As A Climate Change Adaptation Strategy: Case Study Of Mont-Wright Mine, Khalil Hashem, Agus P. Sasmito, Laxmi Sushama, Ferri Hassani, Mehrdad Kermani

Journal of Sustainable Mining

The mining industry faces evolving challenges in adapting to the impacts of climate change. Among these challenges is the management of tailings. This study focuses on investigating surface disposal of non-cemented paste tailings, particularly the effect of water content, freeze-thaw cycles (FTC, defined as freezing the sample to –20°C and thawing it to +20°C), and ambient temperature on the mechanical characteristics and thermophysical properties of paste tailings. The potential for maintaining non-cemented tailings in a frozen state year-round is also investigated through field-scale numerical simulations. Experiment results of thermophysical properties of tailings with water content, freeze-thaw cycles and ambient temperatures …

Continuous Sorption Of Ionic Dyes Onto Nanoporous Faujasite Zeolite And The Regeneration Of The Adsorbent, Frederick O. Oshomogho, Miracle Aisosa Omorogieva

BAU Journal - Science and Technology

This study evaluates the efficiency of synthesized faujasite zeolite in the continuous removal of methylene blue from water and tests the reusability of the regenerated adsorbent. Faujasite Zeolite was synthesized from locally available aluminosilicate clay in Edo State using standard methods documented in the literature. XRF analysis affirmed the elemental composition, showing high levels of silica and alumina, which increased its adsorption capacity. SEM images depicted a crystal-clear structure with an octahedral shape and visible micro-pores on the surface. TGA showed effective thermal stability below 300 ºC, with a 10% weight loss between 28.59 ºC and 300 ºC. BET analysis …

The Prophylactic Effect Of Aqueous Chamomile Extract On Nitrogen Dioxide Exposed Mice, Mariam Kbaysi, Ruzanna Petrosyan, Jamilah Borjac

BAU Journal - Science and Technology

Nitrogen dioxide (NO₂) a gaseous air pollutant resulting from industrial activities. It has been associated to various diseases related to oxidative stress and inflammation, including cardiovascular and nervous system disorders. Chamomile is mainly recognized for its high content of antioxidant flavonoids and is extensively utilized in herbal medicine for treating several disorders. The aim of this study is to examen the protective effects of chamomile extract against NO₂-induced damage in female mice. Balb/c mice were divided into four groups: control, chamomile extract, NO₂ derivatives, and NO₂ derivatives combined with chamomile extract. Upon completion of the study, Blood was …