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Articles 35881 - 35910 of 1738481
Full-Text Articles in Entire DC Network
The Impact Of Genetic Testing On Physician Practice In Specialized Cardiovascular Clinics, Arsalan Hamid, Tyler Sewell, Sucheta Bhatt, Scott Spencer, Damon Hostin, Ginger A Metcalf, Richard A Gibbs, Vijay Nambi, Layla A Abushamat, Christie M Ballantyne
The Impact Of Genetic Testing On Physician Practice In Specialized Cardiovascular Clinics, Arsalan Hamid, Tyler Sewell, Sucheta Bhatt, Scott Spencer, Damon Hostin, Ginger A Metcalf, Richard A Gibbs, Vijay Nambi, Layla A Abushamat, Christie M Ballantyne
Faculty, Staff and Students Publications
Background: Although familial hypercholesterolemia (FH) is a US Centers for Disease Control and Prevention tier 1 condition for genetic testing, the impact of testing on clinical outcomes is unclear.
Objective: We aimed to assess whether genetic testing alters lipid management in HeartCare participants.
Methods: For participants with pathogenic/likely pathogenic variants for FH observed at Baylor College of Medicine cardiology clinics, data on laboratory values, medication prescriptions, and diagnoses were collected and compared before and after genetic testing.
Results: In the 20 participants with APOB/LDLR variants and complete data, low-density lipoprotein cholesterol (LDL-C) was numerically lower but not significantly different before …
Toward Scientific Rigor: Setting Standards For Indirect Calorimetry Analysis And Reporting, Elizabeth L Lieu, Mark A Herman, Sean M Hartig
Toward Scientific Rigor: Setting Standards For Indirect Calorimetry Analysis And Reporting, Elizabeth L Lieu, Mark A Herman, Sean M Hartig
Faculty, Staff and Students Publications
Indirect calorimetry determines energy expenditure by measuring respiratory gas exchange. The approach is based on the principle that nutrient metabolism consumes O2 and produces CO2 and water in predictable ratios that can be compared with heat production. Due to the impracticality and high cost of direct calorimetry, indirect calorimetry is the major approach for modern metabolic studies in preclinical models. Despite the broad adoption of this method in rodent phenotyping, the field has lacked standardized methods for analyzing, representing, and sharing these data, limiting scientific progress. The recent review in Nature Metabolism by the International Indirect Calorimetry Consensus Committee (IICCC) …
Predicting Mortality And Costs After Emergency Department Visits By People With Dementia: Timing And Location Matter, Jason K Bowman, Christine S Ritchie, Kei Ouchi, Kyler M Godwin, James A Tulsky, Joan M Teno
Predicting Mortality And Costs After Emergency Department Visits By People With Dementia: Timing And Location Matter, Jason K Bowman, Christine S Ritchie, Kei Ouchi, Kyler M Godwin, James A Tulsky, Joan M Teno
Faculty, Staff and Students Publications
Background: People with dementia have high rates of emergency department (ED) and hospital utilization, high mortality and costs, and other poor outcomes. To successfully impact the care trajectories of these patients, health care systems must pragmatically identify the correct target population. This study described patterns of ED utilization by people with dementia and explored the accuracy of administrative data models to predict mortality and costs.
Methods: Retrospective cohort study of a 20% random sample of Traditional Medicare (TM) beneficiaries with dementia, age ≥ 66 years, and an index ED visit in 2018. One-year mortality and high costs were described, and …
Rab4 Spatially And Functionally Converges With Rab7 In The Degradative Endolysosomal Network, Stephen M Farmer, Shiyu Xu, Yue Yu, Xin Ye, Haoyi Yang, Jing Cai, Beatriz Rios, Wen-Wen Lin, Daniela Covarrubias, Vicky Chuong, Lili Ye, German Zylberberg, Charissa Wang, Erin Furr-Stimming, Qingchun Tong, Oguz Kanca, Hugo J Bellen, Travis I Moore, Sheng Zhang
Rab4 Spatially And Functionally Converges With Rab7 In The Degradative Endolysosomal Network, Stephen M Farmer, Shiyu Xu, Yue Yu, Xin Ye, Haoyi Yang, Jing Cai, Beatriz Rios, Wen-Wen Lin, Daniela Covarrubias, Vicky Chuong, Lili Ye, German Zylberberg, Charissa Wang, Erin Furr-Stimming, Qingchun Tong, Oguz Kanca, Hugo J Bellen, Travis I Moore, Sheng Zhang
Faculty, Staff and Students Publications
Rab GTPases are key regulators of endosomal trafficking in eukaryotes. In mammalian cells, Rab4 and Rab7 were shown to localize to distinct compartments, with Rab4 on early endosomes for fast recycling and Rab7 on late endosomes for degradation. Here, we show that in Drosophila, endogenous Rab4 and Rab7 extensively colocalize across tissues and developmental stages. Recruited to the same compartments through mechanisms that do not require the activity of the other, they have opposing effects on endolysosomal size: Rab4 overexpression or Rab7 impairment leads to enlarged endolysosomes, whereas Rab4 loss or constitutively active Rab7 reduces their sizes. Rab4 deficiency suppresses …
Lonp1 Variants Are Associated With Clinically Diverse Phenotypes, Randee E Young, Lu Qiao, Rebecca Hernan, David A Sweetser, Jessica L Waxler, Daryl A Scott, Tiana M Scott, Seema R Lalani, Mahshid S Azamian, Jill A Rosenfeld, Bret Bostwick, Lindsay C Burrage, Lance H Rodan, Bianca E Russell, Marina Dutra-Clarke, Michael Kruer, Somayeh Bakhtiarim, Hossein Darvish, David J Amor, Shamima Rahman, Karen Stals, Lisa Bradley, Susan Byrne, Leandra K Tolusso, Beatrix Wong, Laura Benedict, Kimberly Wallis, Kestutis Micke, Cindy Colson, Thomas Smol, Sabrina V Southwick, Kristen A Miller, Michelle L Kush, Odelia Chorin, Annick Rothschild, Wei Wang, Yufeng Shen, Wendy K Chung
Lonp1 Variants Are Associated With Clinically Diverse Phenotypes, Randee E Young, Lu Qiao, Rebecca Hernan, David A Sweetser, Jessica L Waxler, Daryl A Scott, Tiana M Scott, Seema R Lalani, Mahshid S Azamian, Jill A Rosenfeld, Bret Bostwick, Lindsay C Burrage, Lance H Rodan, Bianca E Russell, Marina Dutra-Clarke, Michael Kruer, Somayeh Bakhtiarim, Hossein Darvish, David J Amor, Shamima Rahman, Karen Stals, Lisa Bradley, Susan Byrne, Leandra K Tolusso, Beatrix Wong, Laura Benedict, Kimberly Wallis, Kestutis Micke, Cindy Colson, Thomas Smol, Sabrina V Southwick, Kristen A Miller, Michelle L Kush, Odelia Chorin, Annick Rothschild, Wei Wang, Yufeng Shen, Wendy K Chung
Faculty, Staff and Students Publications
LONP1 encodes a mitochondrial protease essential for protein quality control and metabolism. Variants in LONP1 are associated with a diverse and expanding spectrum of disorders, including Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies syndrome (CODAS), congenital diaphragmatic hernia (CDH), and neurodevelopmental disorders (NDD), with some individuals exhibiting features of mitochondrial encephalopathy. We report 16 novel LONP1 variants identified in 16 individuals (11 with NDD, 5 with CDH), further expanding the clinical spectrum. Structural mapping of disease-associated missense variants revealed phenotype-specific clustering, with CODAS variants enriched in the proteolytic chamber and NDD variants more broadly distributed. CODAS is caused by biallelic …
Risk Factors For Acute Rejection In Pediatric Lung Transplantation And Its Impact On Graft Failure, Sophie Li, Spoorthi Kamepalli, David Moreno Mcneill, Selena Li, Abbas Rana
Risk Factors For Acute Rejection In Pediatric Lung Transplantation And Its Impact On Graft Failure, Sophie Li, Spoorthi Kamepalli, David Moreno Mcneill, Selena Li, Abbas Rana
Faculty, Staff and Students Publications
Background: Although acute rejection is a common complication of lung transplantation, few studies have analyzed risk factors for acute rejection in pediatric lung transplant patients. The purpose of this study was to examine risk and protective factors for acute rejection in pediatric lung transplantation and its impact on graft failure.
Methods: A retrospective analysis was performed on lung transplant data for a cohort of 906 pediatric patients from the Organ Procurement and Transplantation Network (OPTN) Database between October 1, 1987, and June 30, 2023. Multivariable logistic regression was conducted to identify risk and protective factors for acute rejection, adjusting for …
The Diagnostic Performance Of The Basic Versus The Detailed Telomere Flow Fish Test In Young Patients With Aplastic Anaemia, Nicholas F Decleene, Duc T Nguyen, Susan E Kirk, Hannah L Helber, Ghadir S Sasa, Alison A Bertuch
The Diagnostic Performance Of The Basic Versus The Detailed Telomere Flow Fish Test In Young Patients With Aplastic Anaemia, Nicholas F Decleene, Duc T Nguyen, Susan E Kirk, Hannah L Helber, Ghadir S Sasa, Alison A Bertuch
Faculty, Staff and Students Publications
Identifying telomere biology disorders (TBDs) in patients with aplastic anaemia (AA) is essential for guiding appropriate care. Telomere length (TL) measurement by flow cytometry with fluorescence in situ hybridization supports diagnosis, but the real-world performance of the basic test (lymphocytes and granulocytes) versus the detailed test (which includes four lymphocyte subsets) remains unclear. We retrospectively reviewed 439 patients who underwent detailed TL testing at our institution from 2008 to 2022. Haematological disease was present in 87%, with AA comprising 56%. We classified 23 subjects with TBD independently of TL, only one of whom had severe AA (SAA) at initial presentation. …
Bortezomib And Vorinostat In Combination With Mitoxantrone, Dexamethasone, And Pegasparaginase During Induction And Reinduction For Infants With Acute Lymphoblastic Leukaemia: A Multicentre Single-Arm Phase 1/2 Study, Tanja A Gruber, Sima Jeha, Rebecca J Deyell, Victor Lewis, Bill H Chang, Eric J Lowe, Jamie Frediani, Catherine Vezina, Bruno Michon, Michael Richards, Erin H Breese, Thai-Hoa Tran, Norman Lacayo, Christine Bolen, Sunil Desai, Jennifer L Pauley, Minxuan Huang, Emily Ashcraft, Cheng Cheng, Kirk R Schultz, Linda Stork, Krysta Schlis, Van T Huynh, Nathan Gossai, Yoav H Messinger, Henrique Bittencourt, Terzah M Horton, Uma Athale, Duncan Stearns, Deborah Schiff, Paul S Gaynon
Bortezomib And Vorinostat In Combination With Mitoxantrone, Dexamethasone, And Pegasparaginase During Induction And Reinduction For Infants With Acute Lymphoblastic Leukaemia: A Multicentre Single-Arm Phase 1/2 Study, Tanja A Gruber, Sima Jeha, Rebecca J Deyell, Victor Lewis, Bill H Chang, Eric J Lowe, Jamie Frediani, Catherine Vezina, Bruno Michon, Michael Richards, Erin H Breese, Thai-Hoa Tran, Norman Lacayo, Christine Bolen, Sunil Desai, Jennifer L Pauley, Minxuan Huang, Emily Ashcraft, Cheng Cheng, Kirk R Schultz, Linda Stork, Krysta Schlis, Van T Huynh, Nathan Gossai, Yoav H Messinger, Henrique Bittencourt, Terzah M Horton, Uma Athale, Duncan Stearns, Deborah Schiff, Paul S Gaynon
Faculty, Staff and Students Publications
Background: Acute lymphoblastic leukaemia in infants remains a therapeutic challenge. In preclinical studies we previously identified bortezomib and vorinostat as active agents against KMT2A rearranged (KMT2Ar) leukaemia. The aim of this study was to determine the tolerability of incorporating bortezomib and vorinostat into an acute lymphoblastic leukaemia-chemotherapy backbone for newly diagnosed infants with acute lymphoblastic leukaemia both with and without KMT2Ar.
Methods: In this single-arm phase 1/2 study conducted at 18 hospitals in the USA and Canada, we enrolled patients aged 1 year or younger at the time of diagnosis with newly diagnosed acute lymphoblastic leukaemia or undifferentiated leukaemia (with …
Cardiac Catheterization In American Indian/Alaska Native Populations: Empowering Communities, Providers, And Systems Toward Equity, Joseph Burns, Daniel J Penny, Keila N Lopez, Lindsay F Eilers, Athar M Qureshi, Christine J Chung, Jason F Deen
Cardiac Catheterization In American Indian/Alaska Native Populations: Empowering Communities, Providers, And Systems Toward Equity, Joseph Burns, Daniel J Penny, Keila N Lopez, Lindsay F Eilers, Athar M Qureshi, Christine J Chung, Jason F Deen
Faculty, Staff and Students Publications
American Indian/Alaska Native (AI/AN) people face numerous health disparities, including alarming rates of cardiovascular morbidity and mortality. These inequities are closely tied to unique social, political, and economic circumstances due to the ongoing consequences of systemic racism. Although poorly described, these cardiovascular inequities extend to adult and pediatric interventional cardiology. AI/AN adults are less likely to undergo cardiac catheterization and are more likely to experience complications. There are no published studies on pediatric interventional cardiology outcomes in AI/AN children. The scarcity of available data underscores the need for novel studies to investigate the epidemiology, sociodemographic associations, and outcomes of AI/AN …
External Validation Of Calculator For Cesarean Delivery During Induction Of Labor, Claudia J Ibarra, Rachel L Wiley, Han-Yang Chen, Estefania Guthrie, Ipsita Ghose, Hector Mendez-Figueroa, Suneet P Chauhan
External Validation Of Calculator For Cesarean Delivery During Induction Of Labor, Claudia J Ibarra, Rachel L Wiley, Han-Yang Chen, Estefania Guthrie, Ipsita Ghose, Hector Mendez-Figueroa, Suneet P Chauhan
Faculty, Staff and Students Publications
Objective: To validate a published risk calculator to predict cesarean delivery (CD) among singletons undergoing induction of labor.
Methods: Our retrospective cohort study included singletons undergoing induction of labor. A predicted CD score was calculated for each individual based on a previously developed calculator. External validation of the calculator was assessed by the discriminative power of the model by using the area under the receiver operating characteristic curve, and by a calibration curve. The score was categorized as less than 10%, 10% to less than 30%, and 30% or greater. The primary outcome was CD. The secondary outcomes were a …
Creating A News Literate Journalism: A Metacognitive Model For Journalism Practice, Patrick R. Johnson
Creating A News Literate Journalism: A Metacognitive Model For Journalism Practice, Patrick R. Johnson
College of Communication Faculty Research and Publications
This article introduces News Literate Journalism, a metacognitive approach that redefines news literacy as a professional competency. Drawing on interviews with 30 journalists and grounded in news literacy and educational psychology, I argue that ethical, adaptive journalism relies on reflection, regulation and critical reasoning. These behaviors, though embedded in journalistic routines, are often overlooked. The approach presents a new framework for journalism education and practice, one that promotes transparency, fosters trust and supports democratic resilience.
Evaluating The Effects Of Anti-Forensic Activities In Additive Manufacturing Devices, Daniel B. Miller
Evaluating The Effects Of Anti-Forensic Activities In Additive Manufacturing Devices, Daniel B. Miller
Shelby Hall Graduate Research Forum Posters
Additive Manufacturing (AM) is a newer famlily of production tecchologies that constructs objects by fusing layers of material into the desired shape. Methods for achieving this as described in Gibson et al. [1] are varied and include Fused Filament Deposition, Selective Laser Sintering, Stereolithography (SLA), and Powder Bed Fusion. Computers are integral to the processes being responsible for creating and decoding design instructions, collecting and processing sensor data, and, ultimately, directing the activity of the machines which implement the process. Additionally, the AM industry is rapidly expanding, worth an estimated $23 billion in 2023 and projected to reach $88 billion …
Lean On Me: Social Factors And Diabetes Outcomes Among Young Adults With Type 1 Diabetes Prior To Transitioning To Adult Care, Caroline M Roberts, Samantha A Carreon, Charles G Minard, Sarah K Lyons, Randi Streisand, Barbara J Anderson, Tricia S Tang, Siripoom Mckay, Katherine Gallagher, Sridevi Devaraj, Marisa E Hilliard
Lean On Me: Social Factors And Diabetes Outcomes Among Young Adults With Type 1 Diabetes Prior To Transitioning To Adult Care, Caroline M Roberts, Samantha A Carreon, Charles G Minard, Sarah K Lyons, Randi Streisand, Barbara J Anderson, Tricia S Tang, Siripoom Mckay, Katherine Gallagher, Sridevi Devaraj, Marisa E Hilliard
Faculty, Staff and Students Publications
Aims: Little is known about how different aspects of social relationships relate to diabetes self-management and glycaemic outcomes in young adults with type 1 diabetes (T1D). We examined relationships of general and diabetes-specific social variables with diabetes self-management and HbA1c. We hypothesized diabetes-specific factors would more strongly associate with self-management and HbA1c than general social factors.
Methods: We analysed baseline data from 100 young adults with T1D (Mage = 19.9 ± 1.3 years) enrolled in a randomized controlled trial of a paediatric to adult care transition intervention. We examined associations of self-reported general and diabetes-specific social factors with self-reported self-management …
Pharmacodynamics, Efficacy, And Safety Of Intraputaminal Eladocagene Exuparvovec Administered To Pediatric Patients With Aromatic L-Amino Acid Decarboxylase Deficiency Using An Mr-Compatible Cannula: 48 Weeks Of Follow-Up, Daniel J Curry, Phillip L Pearl, Scellig S D Stone, Donald L Gilbert, Sudhakar Vadivelu, Bruria Ben-Zeev, Matthew Vestal, Muhammad Zafar, Chun-Hwei Tai, Sheng-Che Chou, Zion Zibly, Lior Ungar, Mered Parnes, Mariam Hull, Lisa Emrick, Christian Werner, Alexis Krolick, Vinay Penematsa, Antonia Wang, Rezwanur Rahman, Lee Golden, Yin-Hsiu Chien, Paul Wuh-Liang Hwu
Pharmacodynamics, Efficacy, And Safety Of Intraputaminal Eladocagene Exuparvovec Administered To Pediatric Patients With Aromatic L-Amino Acid Decarboxylase Deficiency Using An Mr-Compatible Cannula: 48 Weeks Of Follow-Up, Daniel J Curry, Phillip L Pearl, Scellig S D Stone, Donald L Gilbert, Sudhakar Vadivelu, Bruria Ben-Zeev, Matthew Vestal, Muhammad Zafar, Chun-Hwei Tai, Sheng-Che Chou, Zion Zibly, Lior Ungar, Mered Parnes, Mariam Hull, Lisa Emrick, Christian Werner, Alexis Krolick, Vinay Penematsa, Antonia Wang, Rezwanur Rahman, Lee Golden, Yin-Hsiu Chien, Paul Wuh-Liang Hwu
Faculty, Staff and Students Publications
Aromatic ʟ‐amino acid decarboxylase (AADC) deficiency is a rare pediatric neurotransmitter disorder that typically necessitates lifelong care, and that carries a risk of childhood mortality. Eladocagene exuparvovec gene therapy is designed to restore AADC production. Study GT‐002 (NCT04903288) is a phase 2, multicenter, open‐label trial assessing the pharmacodynamics, safety, and efficacy of eladocagene exuparvovec administered to the putamen bilaterally in pediatric patients with AADC deficiency using a magnetic resonance (MR)‐compatible cannula. Patients received eladocagene exuparvovec at 1.8 × 1011 vector genomes via the SmartFlow MR‐compatible cannula in a single operative session. Endpoints include the change from baseline in …
Validation Of Longitudinal Biomarker Screening Algorithms For Hcc Detection In Patients With Cirrhosis, Amit G Singal, Qingchun Jin, Jorge Marrero, Neehar D Parikh, Anna S Lok, Camden Lopez, Stephanie Page-Lester, Lewis R Roberts, Rajender Reddy, Michelle Luster, Saira Khaderi, Sumeet K Asrani, Hashem B El-Serag, Fasiha Kanwal, Ziding Feng, Nabihah Tayob
Validation Of Longitudinal Biomarker Screening Algorithms For Hcc Detection In Patients With Cirrhosis, Amit G Singal, Qingchun Jin, Jorge Marrero, Neehar D Parikh, Anna S Lok, Camden Lopez, Stephanie Page-Lester, Lewis R Roberts, Rajender Reddy, Michelle Luster, Saira Khaderi, Sumeet K Asrani, Hashem B El-Serag, Fasiha Kanwal, Ziding Feng, Nabihah Tayob
Faculty, Staff and Students Publications
Background: Blood-based biomarker panels, including GALAD, have been proposed as an alternative to abdominal ultrasound for hepatocellular carcinoma (HCC) surveillance. Studies suggest longitudinal evaluation of biomarkers can improve test performance; however, no large studies have validated these findings.
Methods: We leveraged the HCC Early Detection Strategy (HEDS) study (n=1019 patients with cirrhosis; 99 incident HCC) and Texas HCC Consortium (THCCC) (n=2345 patients with cirrhosis; 126 incident HCC) to compare the performance of fixed-threshold GALAD (cutoff of -1.36), and 4 longitudinal algorithms: longitudinal GALAD, PALAD, mFB-ALAD, and mPEB-ALAD. The HEDS cohort was used to derive longitudinal algorithms, and external validation was …
Biomimetic And Bioinspired Materials: Design Strategies, Mechanical Properties, And Engineering Applications-A Review, Manickaraj Karuppusamy, Sivasubramanian Palanisamy, Mahesh Gurusamy, Vijaya Prakash Balasubramanian, Manivannan Jayamani, Subramanian Lakshmi Sankar, Karthikayan Sundararajan, Gokulkumar Sivanantham, Syed Kashif Ali, Murugesan Palaniappan, Mezigebu Belay, Mohamed Abbas
Biomimetic And Bioinspired Materials: Design Strategies, Mechanical Properties, And Engineering Applications-A Review, Manickaraj Karuppusamy, Sivasubramanian Palanisamy, Mahesh Gurusamy, Vijaya Prakash Balasubramanian, Manivannan Jayamani, Subramanian Lakshmi Sankar, Karthikayan Sundararajan, Gokulkumar Sivanantham, Syed Kashif Ali, Murugesan Palaniappan, Mezigebu Belay, Mohamed Abbas
Faculty, Staff and Students Publications
The field of biomimetic and bioinspired materials has progressed rapidly by drawing inspiration from nature's intricate structures and multifunctional systems in order to address pressing challenges in modern engineering. This review critically examines the mechanical performance of these materials, focusing on their hierarchical design principles, synthesis strategies, and versatility of application. Natural exemplars such as nacre, spider silk, and bone are emphasized, as their structural efficiency and functional adaptability have informed the development of synthetic analogues with superior strength, toughness, flexibility, and lightweight characteristics. The review also highlights advanced fabrication methods, such as additive manufacturing and precision chemical synthesis, which …
Testing And Evaluation Of Generative Large Language Models In Electronic Health Record Applications: A Systematic Review, Xinsong Du, Zhengyang Zhou, Yifei Wang, Ya-Wen Chuang, Yiming Li, Richard Yang, Wenyu Zhang, Xinyi Wang, Xinyu Chen, Hao Guan, John Lian, Pengyu Hong, David W Bates, Li Zhou
Testing And Evaluation Of Generative Large Language Models In Electronic Health Record Applications: A Systematic Review, Xinsong Du, Zhengyang Zhou, Yifei Wang, Ya-Wen Chuang, Yiming Li, Richard Yang, Wenyu Zhang, Xinyi Wang, Xinyu Chen, Hao Guan, John Lian, Pengyu Hong, David W Bates, Li Zhou
Faculty, Staff and Students Publications
Background: The use of generative large language models (LLMs) with electronic health record (EHR) data is rapidly expanding to support clinical and research tasks. This systematic review characterizes the clinical fields and use cases that have been studied and evaluated to date.
Methods: We followed the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines to conduct a systematic review of articles from PubMed and Web of Science published between January 1, 2023, and November 9, 2024. Studies were included if they used generative LLMs to analyze real-world EHR data and reported quantitative performance evaluations. Through data extraction, we identified …
Applying Direct Numerical Simulations To Investigate Wave Forcing Against A Vertical Wall, Hunter Boswell, Frank D. Han, Gaurav Savant, Guirong Yan, Wouter Mostert
Applying Direct Numerical Simulations To Investigate Wave Forcing Against A Vertical Wall, Hunter Boswell, Frank D. Han, Gaurav Savant, Guirong Yan, Wouter Mostert
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Current engineering standards lack the ability to predict the peak impact forces of breaking waves impinging directly upon coastal structures. In this study solitary waves impacting vertical and tapered walls are investigated. To capture the detailed physics of the wave profile that impacts the wall, two-dimensional direct numerical simulations are applied to model the wave traveling over a simplified bathymetry consisting of an initially uniform depth, followed by a uniform beach ramp and then terminating in a uniform depth inshore region and vertical wall. Such an approach can simulate wave runup on land and then the impact with the vertical …
March 2026 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean’S Office Communications Team
March 2026 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean’S Office Communications Team
Library & Learning Newsletters
PDF version of the March 2026 (Volume 4, Issue 8) Library & Learning Newsletter.
Uab Libraries News, 03 2026, Uab Libraries
Launch Skills: Virtual Career Camp Connects Rural Youth To Diverse Career Pathways, Caroline Homan, Meagan Hoffman
Launch Skills: Virtual Career Camp Connects Rural Youth To Diverse Career Pathways, Caroline Homan, Meagan Hoffman
Journal of Youth Development
Rural youth often encounter persistent barriers in career and workforce readiness, including limited access to career exploration resources, mentorship, and post-secondary exposure, challenges that are compounded by geographic isolation and higher rates of rural poverty. To address these gaps, this manuscript describes the development and implementation of Launch Skills, a virtual career camp designed to broaden rural youths’ awareness of career pathways within food, agriculture, natural resources management, and human sciences (FANH). Grounded in Positive Youth Development principles, Launch Skills was collaboratively developed by North Dakota State University Extension and South Dakota State University Extension to provide flexible, accessible, and …
Towards Socially Legitimized Trust In Ai-Learning Systems, Sanket Patole, Rob E. Carpenter, Reed M. Milewicz, Rose M. Baker, John R. Turner
Towards Socially Legitimized Trust In Ai-Learning Systems, Sanket Patole, Rob E. Carpenter, Reed M. Milewicz, Rose M. Baker, John R. Turner
Human Resource Development Faculty Publications and Presentations
AI-enabled learning technologies are rapidly becoming institutional infrastructure. In this context, “trust” cannot be treated as a simple user attitude or a byproduct of technical performance. We argue that durable trust in AI-enabled learning systems is fundamentally a legitimacy outcome: stakeholders must judge AI-mediated practices as appropriate, credible, and defensible within the normative and governance structures of learning environments. Building on socio-technical systems scholarship and institutional legitimacy theory, we introduce Socially Legitimized Trust (SLT), a framework that helps us understand adoption stability and contestation through alignment among three foundations: technocratic validation (credible evidence of capability, limits, and reliability), social validation …
A Phenomenological Study Of Teacher And Student Experience Within A Community Of Inquiry: Utilizing Wonder-Infused Pedagogy In An Elementary Outdoor Classroom, Andrew Gilbert, Steph N. Dean
A Phenomenological Study Of Teacher And Student Experience Within A Community Of Inquiry: Utilizing Wonder-Infused Pedagogy In An Elementary Outdoor Classroom, Andrew Gilbert, Steph N. Dean
Publications
This interpretive phenomenological study explores how wonder-infused pedagogy, enacted within an elementary outdoor classroom, supported the development of a community of inquiry. We position the community of inquiry as the overarching framework for cultivating social, cognitive, and teaching presence; wonder as the pedagogical driver; and outdoor learning as the authentic context for engaging in science practices. In response to schooling contexts that often privilege testing and individual achievement over collaborative inquiry, we examined an eight-week outdoor wonder project with third- through fifth-grade students. Data sources included group interviews, student journals, teacher reflections, and photographs. Students engaged in weekly wonder journaling …
Academic Freedom And Collective Bargaining: A Joint Report By The National Center For The Study Of Collective Bargaining In Higher Education And The Professions And The Aaup’S Center For The Defense Of Academic Freedom, William A. Herbert, Isaac A. Kamola, Timothy R. Cain, Erin Ward, Anita Levy, Kathryn Ritchie, Ariana Gonzalez
Academic Freedom And Collective Bargaining: A Joint Report By The National Center For The Study Of Collective Bargaining In Higher Education And The Professions And The Aaup’S Center For The Defense Of Academic Freedom, William A. Herbert, Isaac A. Kamola, Timothy R. Cain, Erin Ward, Anita Levy, Kathryn Ritchie, Ariana Gonzalez
Publications and Research
This is a joint report by the National Center for the Study of Collective Bargaining in Higher Education and the Professions at Hunter College (National Center) and the Center for the Defense of Academic Freedom (CDAF) at the American Association of University Professors. It presents excerpts from forty-five collective bargaining agreements in higher education to demonstrate the wide range of ways academic freedom is defined in contracts, or not, and how the negotiated definitions incorporate, quote, follow, mirror, or deviate from the principles set forth in the 1940 Statement of Principles on Academic Freedom and Tenure (hereinafter 1940 Statement).
A Data-Guided Analytical Framework For Assessing The Value Of Additional Variables In Heart Transplant Decision Making, Ali Dag, Hamidreza A. Dolatsara, Abdullah Asilkalkan, Joseph Ekong, Kamil Ciftci, Ugur Kucuk, Ozlem Cosgun
A Data-Guided Analytical Framework For Assessing The Value Of Additional Variables In Heart Transplant Decision Making, Ali Dag, Hamidreza A. Dolatsara, Abdullah Asilkalkan, Joseph Ekong, Kamil Ciftci, Ugur Kucuk, Ozlem Cosgun
Department of Information Management and Business Analytics Faculty Scholarship and Creative Works
Heart transplantation is a life-saving procedure for patients with end-stage heart failure. The United Network for Organ Sharing (UNOS), which administers the US organ allocation system, substantially expanded the number of clinical and demographic variables collected in its database in 2004. This study examines whether these newly added variables improve the ability to predict survival outcomes for patients on the heart transplant waiting list. An information-gain-based feature selection approach, supported by an extensive review of prior studies, was combined with survival analysis and regularized regression to identify the most influential predictors. Using the selected variables, several classification models, including tree-augmented …
A Data-Guided Analytical Framework For Assessing The Value Of Additional Variables In Heart Transplant Decision Making, Ali Dag, Hamidreza Ahady Dolatsara, Abdullah Asilkalkan, Joseph Ekong, Kamil Ciftci, Ugur Kucuk, Ozlem Cosgun
A Data-Guided Analytical Framework For Assessing The Value Of Additional Variables In Heart Transplant Decision Making, Ali Dag, Hamidreza Ahady Dolatsara, Abdullah Asilkalkan, Joseph Ekong, Kamil Ciftci, Ugur Kucuk, Ozlem Cosgun
School of Business
Heart transplantation is a life-saving procedure for patients with end-stage heart failure. The United Network for Organ Sharing (UNOS), which administers the US organ allocation system, substantially expanded the number of clinical and demographic variables collected in its database in 2004. This study examines whether these newly added variables improve the ability to predict survival outcomes for patients on the heart transplant waiting list. An information-gain-based feature selection approach, supported by an extensive review of prior studies, was combined with survival analysis and regularized regression to identify the most influential predictors. Using the selected variables, several classification models, including tree-augmented …
Development And Evaluation Of The Interdisciplinary Graduate-Level Experiential Global Aging Education Program In The United States: A Case Of The Gerontology In Japan Course, Takashi Yamashita, Flavius R W Lilly, Diane B. Martin, Mio Kamijo
Development And Evaluation Of The Interdisciplinary Graduate-Level Experiential Global Aging Education Program In The United States: A Case Of The Gerontology In Japan Course, Takashi Yamashita, Flavius R W Lilly, Diane B. Martin, Mio Kamijo
Journal of Global Education and Research
The cultural competence of the workforce is increasingly important due to global population aging and the growing diversity of the older population. Experiential learning, particularly through study abroad programs, is a known strategy to enhance these competencies; yet such training remains uncommon in higher education, especially at the graduate level. While the United States is currently a relatively young country with 17% of its population aged 65 years and older, the percentage is projected to increase to more than 21% by the end of this decade. Recognizing the value of learning from a super-aged society, a two-week study abroad course …
Bullying And Discrimination Experiences Of Bhutanese College Students: Prevalence, Impacts, And Responses, Kezang Sherab, John Howard
Bullying And Discrimination Experiences Of Bhutanese College Students: Prevalence, Impacts, And Responses, Kezang Sherab, John Howard
Journal of Global Education and Research
Prior studies as well as media reports have identified bullying and discrimination amongst Bhutanese school and college students as a cause of concern, especially so for a nation with Gross National Happiness as its goal. Bullying and discrimination are associated with negative outcomes and can impact overall well-being. This quantitative study examined bullying and discrimination amongst college students (n = 16) in Bhutan through a self-administered online survey to a representative sample of 2043 (male = 40.8%; female = 55.8%). There was a non-significant decline from the 2016 survey in the reported prevalence of being bullied (from 45.2% to …
Tools To Build Undergraduate Nursing Student Volunteer Confidence In Case Of Disaster, Sadie Apuron, Emily F. Calkins, Natashia Forson, Rhean Kang, Corinne Pickart, Ryan Quan
Tools To Build Undergraduate Nursing Student Volunteer Confidence In Case Of Disaster, Sadie Apuron, Emily F. Calkins, Natashia Forson, Rhean Kang, Corinne Pickart, Ryan Quan
Nursing Leadership in Community Engagement Projects
Building Undergraduate Nursing Student Confidence to Volunteer in Case of Disaster
This paper provides a brief overview of one project in an ongoing collaboration between the nursing department, the Office of Safety and Security, and Health Services at a private university in the Pacific Northwest. The partnership aims to improve disaster response capacity on campus by preparing nursing students to volunteer in medical triage. It builds on a previous project that created a protocol for volunteers and outlined education recommendations (Sebastian et al., 2025). The goal of this project was to create reusable training resources to increase nursing student knowledge …
Building Connections With Graduate Students Through Credit-Bearing Instruction, Michelle Desilets, Kimberly Pendell
Building Connections With Graduate Students Through Credit-Bearing Instruction, Michelle Desilets, Kimberly Pendell
Library Faculty and Staff Publications and Presentations
Graduate students often need support with research skills and other professional development that is under-recognized by their programs. Librarians play a key role in helping students fill in these gaps. This case study reviews student feedback on a librarian-developed and -delivered credit-bearing course. The course, Library Research and Scholarly Communication Fundamentals, is offered to graduate students across all disciplines. The curriculum is flexible and applicable to each student’s research, covering topics such as researching literature, citation and data management, and publishing in scholarly journals. The course has generated positive and constructive feedback from students, encompassing themes of self-efficacy, improved research …