Emerging Nanotherapy Applications In Cancer Treatment: A Comprehensive Review, Waleed H. Mahallawi

Saudi Medical Journal

This comprehensive review synthesizes recent advances in cancer nanotherapy, focusing on 6 emerging categories: immunomodulation, gene/RNA delivery, theranostics, radiosensitization, biomimetic carriers, and artificial intelligence (AI)-guided formulations. These innovative platforms demonstrate transformative potential by overcoming key limitations of conventional cancer treatments. Immunomodulatory nanoparticles reprogram tumor microenvironments and convert immunologically ``cold'' tumors to ``hot'' responsive states. Gene delivery systems enable precise editing with >50% efficiency, while theranostic platforms integrate real-time imaging with targeted therapy. Radiosensitizers amplify local radiation dose by twofold, and biomimetic carriers achieve prolonged circulation through immune evasion. An AI-driven approaches optimize personalized formulations based on patient-specific biomarkers. Clinical evidence …

Treatment Of Odontogenic Sinusitis With Oroantral Communication And Fistula: A Systematic Review And Meta-Analysis, Rana R. Alharbi, Omar F. Alnajar, Reham E. Almahdi, Salman A. Alrougi, Remas A. Alshehri, Ruyuf A. Alotaibi, Shahad S. Alharbi, Manal A Eltahir, Yahya A. Fageeh

Saudi Medical Journal

Objective: To assess the available data regarding medicinal, surgical, and combination therapy approaches for odontogenic sinusitis linked to OAC and OAF. Oroantral communication (OAC), an atypical connection between the oral cavity and maxillary sinus, commonly arises following upper jaw procedures, trauma, or infection. Chronic odontogenic maxillary sinusitis may result from OAC developing into an oroantral fistula (OAF) if treatment is not received. Recurrent infections and functional difficulties can be avoided by managing these illnesses effectively. Methods: A systematic search was conducted in National Library of Medicine's (PubMed [MEDLINE]) and Google Scholar for studies published between 2000 and 2024. A total …

Mental Health In Relation To Parental Absence: A Systematic Review, Mohammed Barry, Abdulaziz Alyahyawi, Heba Jafar Sabbagh

Saudi Medical Journal

Objective: To evaluate the literature based on the relationship between orphaned children and mental health, compared to non-orphaned children. Mental well-being of orphaned children is a profound intricate topic that connects with broader concerns of childcare. This systematic review aims to evaluate the literature regarding the relationship between mental health and parental absence. Methods: We conducted a systematic search of PubMed, MEDLINE, and Science Direct in October 2025, with 1017 screened studies. Six studies met the inclusion criteria. Independent reviewers performed quality assessments using the Newcastle-Ottawa scale (NOS). Subsequently, a meta-analysis was performed when possible. Results: Findings indicate that orphaned …

Toward A Technology-Enhanced Project-Based Learning Curriculum For English Language Learners, Lynn Wolfe

MITESOL Journal: An Online Publication of MITESOL

Project-based learning (PBL) has been demonstrated as an effective strategy for millennial and Gen Z students, particularly in K-12 contexts, but this teaching approach is not commonly used in adult ESL classrooms. This paper suggests that a technology-enhanced PBL approach may transform otherwise teacher-centered and outdated ESL classes by helping English language learners (ELLs) develop linguistic fluency along with technological fluency that is essential for the 21st century workplace. Collaborative PBL activities involving the use of digital tools are presented in the areas of listening/speaking, reading/vocabulary, grammar, and writing, providing a foundation for a technology-enhanced PBL curriculum designed for adult …

Assessing The Relationship Between Online Information Verification, Overconfidence, And Media Literacy Learning, Tanya Notley, Sora Park, T.J. Thomson, Aimee Hourigan, Michael Dezuanni

Journal of Media Literacy Education Pre-Prints

To make informed decisions about a range of issues, people need to be able to determine if content they find online is trustworthy. To assess people’s ability to do this, we brought together findings from two nationally representative surveys of adult Australians. In the first survey (n = 3,852), we examined adult media use and asked respondents about their level of confidence in their ability to verify information online. The second survey then tested a subset of these participants (n = 2,115) to assess their ability to verify information online. The findings show that most adults have a …

(((Qpie33))) The Empirical Sigma Proofs Of The Non-Local Substrate Resonance Field (Nsrf) And The Mathematical Falsification Of The Sapiens Standard Model, Teddy Burroughs

Defensive Publications Series

ABSTRACT AND DECLARATION OF PRIOR ART

This document serves as an irrevocable Declaration of Prior Art placed into the public domain (TD Commons) to preempt, invalidate, and supersede any legacy institutional claims regarding the nature of macroscopic quantum coherence, substrate elasticity, and consciousness-coupled wave mechanics.

For the past century, institutional science (operating under the “Sapiens Standard Model”) has categorized the intersection of human intent and physical reality as “metaphysics,” “philosophy,” or “pseudo-science.” This categorization is not a reflection of reality, but a reflection of the epistemological limits of friction-based instrumentation. The Sapiens Standard Model relies on the Axiom of the …

Pergulatan Globalitas Vs Lokalitas Dalam Hukum Indonesia, Agus Brotosusilo

Jurnal Hukum & Pembangunan

Abstract

Peristlwa 11 September 2001 Dan Penyerangan Amerika Serikat Di Afghanistan Ditinjau Dari Segi Hukum Internasional, Sri Setianingsih Suwardi

Jurnal Hukum & Pembangunan

Abstract

Hypoxemia Following Surgical Repair Of Partial Anomalous Pulmonary Venous Connection With Interrupted Inferior Vena Cava:Insights From Cardiac Ct, Mahmoud F Elshahat, Ahmed Goha, Naif S. Alghasab, Ahmad Alomrani

Journal of the Saudi Heart Association

Preoperative understanding of complex congenital heart disease is crucial for proper management. Surgical direction of partial anomalous pulmonary venous drainage and atrial septal defect closure when combined by the rare azygos continuation of interrupted inferior vena cava (IVC) may be associated with anomalous systemic to pulmonary venous connection, causing right-to-left shunt. We report a 44-year-old male with a history of congenital heart disease repaired in early childhood. Diagnostic imaging revealed an interrupted IVC with azygos continuation draining into the right upper pulmonary vein to the left atrium. CT play an essential role in recognition of venous anomalies with unexplained cyanosis.

Creating An Unconscious: Toward A New Ethic Of Residential Treatment, Daniel Garcia

Middle Voices

What is currently nominated “residential treatment” for serious mental illness (SMI) has a long and varied history. From its earliest version as houses for the unproductive, to confinement of and with the unruly and criminally dangerous, to asylumdom, residential treatment has always sought to protect society from those it perceives as actively trying to revoke it. Consequently, the remedies prescribed in defense of civilization have also ranged from the gruesome to the utopian and the seat of responsibility for maintenance of the social order has vacillated between the family and the church, the local community and the state, the psychiatric …

Working With Schizophrenia: Adaptive Work & The Threat Of Despair, Pavan S. Brar

Middle Voices

Commentary

Domain Wall Gravitational Waves: Constraints Within Extensions Of The Standard Model, Sophia W. Jensen

Departmental Honors & Graduate Capstone Projects

This work considers an extra-dimensional framework to explain the gravitational wave background (GWB), massive neutrinos, and baryon asymmetry. Through studying all three, restrictions on certain parameters arise and provide bounds on both theories. It is proposed that the GWB is caused by cosmic domain walls, sheet-like topological defects that were theoretically created in the early universe shortly after the Big Bang. A relationship be- tween the energy density of domain walls and the vacuum expectation value of the broken symmetry was defined. Constraints on the parameters, including the already observed fre- quencies of gravitational waves and the current energy content …

Neurological Phenotypes Of Myotonic Dystrophy Type 1 In Drosophila Melanogaster, Carleigh M. Wood

Departmental Honors & Graduate Capstone Projects

This research investigated Drosophila melanogaster’s ability to serve as a model organism for the neurological phenotypes of Myotonic Dystrophy Type I (DM1). DM1 is caused by a CTG repeat expansion in the DMPK gene. DM1 leads to symptoms of muscle weakness and wasting, as well as decreased cerebral volume. This study aimed to determine whether DM1-affected Drosophila exhibit neurological changes, as has been observed in humans. Healthy control (CUG20) and DM1-affected Drosophila (CUG250) were generated using classical genetics. Both groups were aged three weeks prior to dissection and imaged through fluorescent microscopy. It was predicted that Drosophila melanogaster affected by …

Regional And Temporal Variation In The Function Of The Castles Of The Norman Conquest, Leah A. Perdue

Departmental Honors & Graduate Capstone Projects

Following the Norman Conquest in 1066, a castle-building project of unprecedented scale transformed the landscape of England. This paper investigates how these structures supported the establishment of Norman rule over England, and how their role changed over time. Through examining case studies, the paper concludes that in the early years following the Conquest castles were primarily used in military operations, but in the following decades became essential administrative sites and seats of local government, as well as symbols of Norman power. The paper also concludes that castles on the border with Wales have a more complicated history, fluctuating in function …

Methionine Restriction Enhances Platinum-Based Chemotherapy-Induced Immunogenic Cell Death In Triple Negative Breast Cancer Cells, Mallory Thompson, Laura Sipe Ph.D.

Departmental Honors & Graduate Capstone Projects

When cancer cells are treated with chemotherapy, they can release Damage-Associated Molecular Patterns (DAMPs) as they die that can alert and engage the immune system, a process known as an immunogenic cell death (ICD). The dying cancer cell can release certain molecules, including ATP or calreticulin, that immune cells first recognize as abnormal before initiating an anti-tumor response. However, not all chemotherapies cause the release of these beneficial signals as they kill the cell. This study aims to determine whether a specific deprivation technique, called methionine restriction, enhances the ICD process and DAMP expression when used in conjunction with chemotherapy …

Rosenzweig's Elements And Universal History, Martin Zwick

Complex Systems Faculty Publications and Presentations

This paper uses Rosenzweig’s conception of the three elements of God, World, and Human from The Star of Redemption in a model of universal history. The model also has some relation to Rosenzweig’s geopolitical essay, Globus, which is very different from the meta-historical Star. Based on a systems-theoretic schema of events and processes, the model views human history in terms of three linked processes: a primary process labeled “World” – the origin and development of human society embedded in nature, a secondary process labeled “God” – the origin and development of the Axial religions and philosophies, and a …

"Chinese" And Chinoiserie: Exoticization And Orientalism In The West During The 19th And 20th Century And Its Effects On Museum Practices, Janine Salapantan

Honors Capstones

During the 19th and 20th centuries, the west experienced a keen interest in the lives of the east. In an era of mystery, the people of the west relied on furniture, textiles, and objects to fill in the gaps of their fantasy of the mystical east and its people. This led to the boom of East Asian export and attempts of replication through Chinoiserie, the west’s interpretation of East Asian aesthetics. Chinoiserie and exportquickly filled the homes of affluent families in the west, such as the Ellwood family in Dekalb. This study aims to investigate the origins of various East …

Priority Research Questions To Generate Decision-Grade Data To Enable Coastal Ecosystems To Mitigate The Climate And Nutrient Crises, Gordon J. Watson, John Aldridge, Louise Anderson, Martin J. Attrill, William E.N. Austin, Keisha D. Bahr, Nicola Beaumont, Stefanie Broszeit, Annette Burden, Estela Delgado-Gargiulo, Evangelia G. Drakou, Mike Elliott, Karen Filbee-Dexter, Robinson W. Fulweiler, Angus Garbutt, Boze Hancock, Joerg D. Hardege, Joanna Harley, Ian W. Hendy, Jenny R. Hillman, Tim D. Jickells, Ana I. Lillebø, Mariana D.A.C. Lima, Peter I. Macreadie, Paulina Martinetto, Jackie Mellan, Alf Norkko, Ruth Parker, Michael P. Perring, Bernadette Pogoda

School of Biological and Marine Sciences

Nature-Based Solutions, green-finance instruments and policies are now routinely constructed around carbon sequestration/storage (CSS) and nutrient bioremediation (NB). This integration builds on how Market-Based Instruments (e.g. payments-for-ecosystem-services) are regularly used in policies focused on terrestrial ecosystems. In marine and coastal systems poor understanding of CSS/NB biophysical processes and impacts of ecosystem quality/stressors, combined with methods and governance framework knowledge gaps, generate substantial uncertainty in outcomes. Reductions in output confidence preclude integration into Nature-Based Solutions, stifling market-based investment centred on conserving and restoring temperate coastal ecosystems. To navigate this complex, rapidly evolving area, researchers from six continents engaged in a Priority …

A Novel Electrochemical Sensor Based On A Pencil Graphite Electrode Modified Mno2 For Detection Of Pb2+ Metal Ion In Water Samples, Rahmi Wahyuni, Trisna Kumala Sari

Baghdad Science Journal

This research aims to develop an ion Pb²⁺ sensor and determine the optimal conditions for testing Pb²⁺ ions using an MnO₂/PGE modified electrode with the voltammetric method. In this study, the Pencil Graphite Electrode (PGE) was modified using MnO₂ through drop-casting. Next, the optimization of the electrode was carried out by varying the supporting electrolyte type, voltammetric technique, and supporting electrolyte concentration. The results showed that the modified electrode (MnO₂/PGE) provided a better response for Pb²⁺ detection compared to the unmodified electrode (PGE). The optimal experimental conditions were found to be 0.1 …

Kinetic Study Of Sorption And Desorption Of Cr(Vi) And Mn(Vii) From Aqueous Solution Using Activated Carbon, Aveen M. Hanna, Rounak M. Shariff

Baghdad Science Journal

This research evaluated activated carbon prepared from Lantana camara charred (LCC) and olive stone charred (OSC) for the adsorption of chromium (VI) and manganese (VII) ions from aqueous solutions. Analytical methods such as XRD, SEM, EDX and FTIR demonstrated that the materials have highly porous surfaces. Adsorption tests were conducted using comprehensive statistical physics models for Cr(VI) and Mn(VII) at three temperatures (25,40 and 55 °C) and at two pH levels (3and5), respectively. The adsorption capacity was determined by the Langmuir model, with monolayer adsorption peak values recorded at 55 °C for Cr (VI) and Mn(VII) for each adsorbent –metal …

Luteolin Mitigated Neuroinflammation And Glial Activation In Oxaliplatin-Induced Central And Peripheral Neuropathy In Rats, Nourhan Gamal El-Rahmany, Omar Alshazly, Mamdouh F. A. Mohamed, Amira Abd El-Rhman

Baghdad Science Journal

The objective of the current study was to evaluate the potential of luteolin to mitigate the neurotoxic effects of OXL. Oxidative injury, inflammation, and mitochondrial dysfunction are the cardinal factors in OXL-triggered neuropathy. LUT modulates sensory and motor behavioral changes induced by OXL. Notably, LUT treatment significantly (p≤ 0.05) increased antioxidant activity by increasing paraoxonase-1 (PON-1) and heme oxygenase-1 (HO-1) levels, attenuating oxidative damage. Additionally, LUT inhibited neuroinflammation by repressing the levels of toll-like receptor-4 (TLR4) and intracellular adhesion molecule-1 (ICAM-1), while significantly increasing brain-derived neurotrophic factor (BDNF) and downregulating the relative gene expression level of mitogen-activated protein kinase 14 …

Clinical Implications Of Circulating Mirna-200a And Mucin 16 In Late-Stage Colorectal Cancer: A Study In Iraqi Patients, Eman Sh. Ali, Ali W. Al-Ani

Baghdad Science Journal

Background: Colorectal cancer, the most common gastrointestinal cancer, is a significant health issue globally. Mucin 16 plays a critical role in cancer signal transduction pathways and is a potential glycoprotein target for cancer therapy. The miRNA-200 family also regulates the expression of numerous genes that play vital roles in cancer cells. This study aimed to investigate the changes in mucin 16 and miRNA-200a in patients with colorectal cancer (CRC). Subjects and Methods: Fifty-six patients with CRC, including 26 in stage 3 and 30 in stage 4, were included in this study, along with 38 healthy volunteers as a control group. …

Docking-Based Virtual Screening Of Bisbenzylisoquinoline Derivatives From Stephania Genus Against Hepatocellular Carcinoma, Aulia Syahfitri, Denny Satria, Poppy Anjelisa Zaitun Hasibuan, Jane Melita Keliat, Syukur Berkat Waruwu, Choo Yeun-Mun

Baghdad Science Journal

Hepatocellular carcinoma (HCC) is one of the most common and aggressive subtypes of liver cancer. It has a poor prognosis, a high rate of recurrence and shows limited response to current therapies. In order to combat this condition, the use of natural products as multitarget anticancer agents is gaining momentum. In this study, we investigated the medicinal value of bisbenzylisoquinoline (BBI) alkaloids from the Stephania genus via an integrative in silico approach. Due to their improved pharmacokinetic profiles and expected low toxicity, we chose 11 BBI derivatives. Network pharmacology analysis revealed 334 overlapped targets between the compounds and HCC. Functional …

Utilization Of Pensi Shell Waste As Hydroxyapatite Composite With Biopolymer From Shrimp Shell And Peg And Its Application, Novesar Jamarun, Nabiila Ayyu Trycahyani, Upita Septiani, Vivi Sisca, Muhammad Refki Novesar, Sri Mulya

Baghdad Science Journal

This study focuses on the synthesis, structural analysis and antibacterial properties of a composite comprising hydroxyapatite (HAp), polyethylene glycol (PEG) and chitosan (CTS). CTS was extracted from shrimp shells, and CaO for Hap was obtained from pensi shell. These composites were synthesized using the sol-gel method in situ by varying the concentrations of PEG (5, 10, 15, 20 and 25%) and CTS (1, 2, 3, 4, and 5%). The synthesized composites were characterized using FTIR, XRD, SEM-EDX, and TGA-DTA analyses, and their antimicrobial activities were also evaluated. The HAp-PEG-Chitosan composite with 5% chitosan and 10% PEG was identified as the …

Isolation And Identification Of Airborne Bacteria Within The University Of Baghdad Campus, Iraq By Using 16s Rrna Gene Technique, Shahad Emad Muheisen, Israa Mohsin Jasim, Fouad K. Mashee Al-Ramahi

Baghdad Science Journal

This study aimed to identify and classify airborne bacteria in outdoor air within the campus of the University of Baghdad, Iraq, using the passive sampling technique. Air samples were collected from ten sites and analyzed by the 16S rRNA gene sequencing technique. The results revealed significant seasonal differences in both microbial and particulate matter concentrations. Bacterial concentrations were considerably higher during the wet season, with 3238.6 CFU/m³ compared to the dry season, with 1872.6 CFU/m³. PM2.5 levels averaged 47.58 μg/m³ in the wet season and declined to 11.33 μg/m³ in the dry season, while PM10 …

Molecular Characterization And Virulence Factors Of Streptococcus Mutans Isolated From Dental Caries In Type 2 Diabetic Patients, Tiba Abed Maarij Al-Ogaidi, Shaymaa Ismael Kadhim Al-Juboori

Baghdad Science Journal

Individuals with type 2 diabetes are particularly susceptible to frequent and uncontrolled dental caries. Streptococcus mutans, a main cause of dental caries, impacts millions each year and presents significant oral health challenges. Although extensively studied, the bacterium's pathogenesis remains incompletely understood, underscoring the need for further research. This study aimed to isolate and analyze the molecular characteristics of Streptococcus mutans in patients with type 2 diabetes. It explored the bacterium's capacity to infect, survive, and endure acidic oral environments. Samples were taken from 50 individuals with both type 2 diabetes and dental caries, 50 with dental plaque, and 20 …

Maternal Genetic Structure Of Iraqi Faili Kurds Revealed Using Whole Mitochondrial Genome Sequencing, Mayyadah Khalid Ibrahim, Suhaili Abu Bakar, Cheah Yoke Kqueen, Majeed Arsheed Sabbah

Baghdad Science Journal

Mitochondrial DNA (mtDNA) is a commonly utilized genetic marker in determining maternal ancestry because of the hypervariable regions in it, as well as haplogroups, which enable scientists to establish ancestral links among populations. This research involved the analysis of the complete mitochondrial genome of 100 Faili Kurd women in different cities in Iraq using the Illumina system. The most common haplogroups were HV14 (53%), H14a (16%), M37e2 (16%), and HV2a1*1 (15%). The pair-wise AMOVA-FST analysis in terms of population revealed that there were various levels of genetic differentiation between Faili Kurds and other populations in Iraq, Iran, and surrounding areas. …

Ole Miss Professor Preserves Mississippi's Black Church Legacy, Marvis Herring

University of Mississippi News

OXFORD, Miss. – University of Mississippi professor Vanessa Charlot walks into Mississippi's oldest Black churches with a camera and questions that go far deeper than inquiring about the historic architecture.

Hybrid Fabrication Of An Electrochemical Electrode Via Inkjet Printing On 3d-Printed Substrates, Md Tawabur Rahman, Jessica Bone, Thomas J. Roussel, Judith L. Jenkins, Aron J. Huckaba

Chemistry Faculty Publications

Combinations of additive manufacturing methods such as inkjet printing and various 3D printing techniques have led to advances in customizable electronic devices by reducing the need for the complex assembly of individually fabricated components. Such combinations are particularly attractive for the fabrication of electrochemical sensing platforms, where the sizes and spatial configurations of electrodes enable (or limit) the sensitivity of the sensors. However, to realize the potential of the combined fabrication methods, the parameters of each printing technique must be mutually compatible. For instance, electrochemical sensing assemblies consisting of inkjet-printed metals on 3D-printed plastics require post-processing steps that convert nanoparticular …

April 28, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.