Digital Commons Network^™

Caring, 1998 Winter, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue features services for IMMC's elderly patients, including home health care and the Warren Barr Adult Day Care Program.

Caring, 1999 Winter, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue has feature stories on HIV/AIDS inpatient care, advanced practice nursing, and an intergenerational program of middle school students and elderly residents at the Warren Barr Pavilion.

Caring, 1999 Fall, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue has a feature story on medical education at IMMC and a new Surgical Intensive Care Unit.

Long Covid Is Not A Functional Neurologic Disorder, Todd E. Davenport, Svetlana Blitshteyn, Nicola Clague-Baker, David Davies-Payne, Glenn J. Treisman, Sarah F. Tyson

Pacific Faculty Work

Long COVID is a common sequela of SARS-CoV-2 infection. Data from numerous scientific studies indicate that long COVID involves a complex interaction between pathophysiological processes. Long COVID may involve the development of new diagnosable health conditions and exacerbation of pre-existing health conditions. However, despite this rapidly accumulating body of evidence regarding the pathobiology of long COVID, psychogenic and functional interpretations of the illness presentation continue to be endorsed by some healthcare professionals, creating confusion and inappropriate diagnostic and therapeutic pathways for people living with long COVID. The purpose of this perspective is to present a clinical and scientific rationale for …

Rachel Spivack V. City Of Philadelphia

2024 Decisions

USDC for the Eastern District of Pennsylvania

Antimicrobial Resistance In Equines: A Growing Threat To Horse Health And Beyond-A Comprehensive Review., Ajran Kabir, Bibek Lamichhane, Tasmia Habib, Alexis Adams, Hossam El-Sheikh Ali, Nathan M Slovis, Mats H. T. Troedsson, Yosra A. Helmy

Veterinary Science Faculty Publications

The equine industry holds substantial economic importance not only in the USA but worldwide. The occurrence of various infectious bacterial diseases in horses can lead to severe health issues, economic losses, and restrictions on horse movement and trade. Effective management and control of these diseases are therefore crucial for the growth and sustainability of the equine industry. While antibiotics constitute the primary treatment strategy for any bacterial infections in horses, developing resistance to clinically important antibiotics poses significant challenges to equine health and welfare. The adverse effects of antimicrobial overuse and the escalating threat of resistance underscore the critical importance …

Signs And Symptoms Of Serious Illness In Infants Aged Up To 6 Months: Rapid Review Of Clinical Guidelines, Inocencio Daniel Cortes Maramba, Emma Lim, Julie Christine Menzies, Ruud Nijman, Shang-Ming Zhou, Jos M Latour

School of Nursing and Midwifery

BACKGROUND: There is a need to empower parents and carers of young infants to recognise signs of serious illness and to act on these appropriately. Compiling the signs and symptoms of serious illness in infants found in clinical guidelines will support the evidence-based update of the 30+-year-old content of the Baby Check App to empower parents and carers.

OBJECTIVE: To systematically review clinical guidelines for signs and symptoms related to serious illness in infants aged 6 months and below.

METHODS: A rapid review was carried out by searching PubMed, CINAHL, NICE, Cochrane and Embase for clinical guidelines reporting signs and …

The Association Between Prolonged Sars-Cov-2 Symptoms And Work Outcomes, Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L. Rising, Kari A Stephens, Erica S Spatz, Robert A Weinstein

Department of Emergency Medicine Faculty Papers

While the early effects of the COVID-19 pandemic on the United States labor market are well-established, less is known about the long-term impact of SARS-CoV-2 infection and Long COVID on employment. To address this gap, we analyzed self-reported data from a prospective, national cohort study to estimate the effects of SARS-CoV-2 symptoms at three months post-infection on missed workdays and return to work. The analysis included 2,939 adults in the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) study who tested positive for their initial SARS-CoV-2 infection at the time of enrollment, were employed before the pandemic, and completed …

Monkeypox Presenting As Periorbital Cellulitis: A Case Report, Unaiza Batool, Fahad S. Siddiqui, Jessika Sanz, Shoaib Siddiqui

GME Publications

Monkeypox, a viral disease caused by the monkeypox virus is well known for its characteristic rash with macular, papular, and vesicular stages. Although the skin is one of the most affected organs by monkeypox, the virus can also impact the respiratory, ophthalmologic, genitourinary, and gastrointestinal systems, among others. It is extremely common for the disease to begin with flu-like symptoms in the prodromal phase before cutaneous manifestations emerge. Here, we describe a unique case of monkeypox infection in which a patient first presented with periorbital cellulitis before any characteristic skin findings appeared. The source of the infection was unknown and …

“Ain’T Nuthin Wrong With Being A Trojan Man”: Discourse On Safe-Sex In Rap Music, 1985-1995, Christopher D. Rounds, Kareem R. Muhammad

Journal of Hip Hop Studies

This essay methodically tracks references to safe-sex in rap music and analyzes their implications. Reviewing over 3,000 songs from 1985 to 1995, the authors found that the tone and messages of these references differed substantially. While many artists celebrated risky and indiscriminate sexual behavior– their work marred by a misogny and homophobia that often stigmatized persons living with sexually transmitted diseases (STDs)– many other artists portrayed safe-sex in a positive light, either as a responsible approach to sexual behavior, or as a pragmatic tool of urban survival. These songs normalized the use of condoms, and educated listeners by raising awareness …

Intermittent Fasting As An Adjuvant To Standard Drug Therapy For Drug Resistant Epilepsy, Jake Smiech

Yale School of Medicine Physician Associate Program Theses

Epilepsy affects about 70 million people worldwide, making it the world’s second most common neurological disease. The first line treatment for epilepsy are anti-seizure medications, but only two-thirds of patients respond to the first two medications given. We propose a randomized controlled study utilizing intermittent fasting as a therapeutic lifestyle modification as an adjuvant to standard drug therapy for those that experience drug-resistant epilepsy. We will assess the efficacy and safety of intermittent fasting for a period of six months, and statistically determine if there is a significant reduction in the mean frequency of seizures participants experience compared to a …

Co-Localization Of Osteoclasts Differentiation Markers In An Implant Model In Diabetic Mice, Diego Adobbati, Deborah Rocha Seixas, Danieli Rodrigues, Claudia C. Biguetti

School of Podiatric Medicine - Student Research

Introduction and Hypothesis: Diabetes can impair implant osseointegration and impact implant functionality. While significant research has focused on osteogenesis during the osseointegration, little attention has been given to pre-osteoclast differentiation. We hypothesize that diabetes increases pre-osteoclast activity potentially leading to implant failure. This study aims to identify and localize osteoclast markers, specifically DC-STAMP (Dendritic Cell-Specific Transmembrane Protein) and NFATc2 (Nuclear Factor of Activated T-cells, cytoplasmic 2), in diabetic (D) and non-diabetic (ND) mice.

Methodology: Twenty-four 16-week-old male 129 Sv mice (12 diabetic and 12 non-diabetic) underwent implantation with a 0.5x1.5 mm commercially pure titanium screw in the right maxillary bone. …

Comparative Efficacy Of Transthoracic Vs. Transesophageal Echocardiogram In Diagnosing Endocarditis, Mackenzie Johnstone, Raul E Davaro Md

Research Scholars

No abstract provided.

In Silico Analysis Of The Rop29 Protein As A Vaccine Candidate Against Toxoplasma Gondii, Amir Karimipour-Saryazdi, Fatemeh Ghaffarifar, Abdolhossein Dalimi, Masoud Foroutan, John Horton, Javid Sadraei

Faculty, Staff and Student Publications

The progression of Toxoplasma gondii (T. gondii) invasion is aided by rhoptry proteins (ROPs), which are also crucial for the parasite's survival in host cells. In this study, in silico analysis was performed to examine the various aspects of the ROP29 protein, such as physicochemical properties, potential T- and B-cell epitopes, and other significant features. The research revealed that there were 55 possible sites for posttranslational modification in the ROP29 protein. The secondary structure of the ROP29 protein consists of a random coil, an alpha-helix, and an extended strand, which account for 49.69%, 36.81%, and 13.50%, respectively. Moreover, …

Impact Of Covid-19 On Dental Students’ Mental Health Status And Perception Of Sars-Cov-2 Vaccine, Man Hung, Nicole Hablitzel, Sharon Su, Samantha Melnitsky, Amir Mohajeri

Pacific Faculty Work

The COVID-19 pandemic disrupted dental education significantly, forcing adaptations in both didactic and clinical curricula. This study evaluates the impact of COVID-19 on dental students’ mental health and perceptions of the SARS-CoV-2 vaccine. An anonymous online survey was administered to dental students at Roseman University of Health Sciences, focusing on health experiences and vaccination perceptions. Results showed 56.8% of students were concerned about their emotional health, 82.1% felt stressed, and 60.6% felt depressed. About 81.9% received the vaccine, with 75.5% believing it effective, though only 55.3% supported mandatory vaccination. The pandemic negatively impacted students’ emotional health, indicating a need for …

Risk Factors Associated With Pyogenic Spinal Infections Among Intravenous Drug Users And Nonusers, Vivek Biololikar, Brendan Gleason, Lee Kripke, Robert Merrill, Colin Whitaker, Jon Handal

Einstein Health Papers

PURPOSE: To identify the differences in patient factors, presentation, treatment course, and outcomes of intravenous drug users (IVDA) vs. nonusers (non-IVDA) presenting with pyogenic spinal infections.

METHODS: We identified all cases involving spinal infections at our institution between May 2017 and January 2023. Postsurgical infections were excluded, and patients were separated into IVDA and non-IVDA groups. The patient charts were reviewed and analyzed for statistical or clinically significant differences using RStudio (2019 version 3.6.2). Our institutional review board approved this study, IRB# 2020-277, iRISID-2023-1384.

RESULTS: Fifty patients (29 males and 21 females) with primary pyogenic spinal infections were included in …

Selection For Robust Metabolism In Domesticated Yeasts Is Driven By Adaptation To Hsp90 Stress, Natalia Condic, Hatim Amiji, Dipak Patel, William Charles Shropshire, Nejla Ozirmak Lermi, Youssef Sabha, Beryl John, Blake Hanson, Georgios Ioannis Karras

Faculty, Staff and Student Publications

Protein folding both promotes and constrains adaptive evolution. We uncover this surprising duality in the role of the protein-folding chaperone heat shock protein 90 (Hsp90) in maintaining the integrity of yeast metabolism amid proteotoxic stressors within industrial domestication niches. Ethanol disrupts critical Hsp90-dependent metabolic pathways and exerts strong selective pressure for redundant duplications of key genes within these pathways, yielding the classical genomic signatures of beer and bread domestication. This work demonstrates a mechanism of adaptive canalization in an ecology of major economic importance and highlights Hsp90-dependent variation as an important source of phantom heritability in complex traits.

Antimicrobials Produced By Ants: Chemical Properties And Microbe Specificity, Katy Chon

Master's Theses

Antibiotic resistance is a growing public health concern worldwide, and for over a decade, we have been witnessing the growth of difficult to treat infectious diseases caused by bacteria that are becoming resistant to antibiotics. This resistance can be mostly related to the misusing and improper use of antibiotics in both humans and animals. To restore this problem, humans have turned to new sources for the production of antibiotics. In this study, we focused on using ants. Social insects, including ants and bees, have faced strong disease pressures during their evolution and have developed a range of methods to fight …

Adherence To Guideline-Based Treatment Of Recurrent C. Difficile Within Lvhn Hospitals, Zoe Tarun, Kathryn Zaffiri Mph, Eric Young Md, Jarrod W. Kile Rphd

Research Scholars

No abstract provided.

Trends Of Methicillin-Resistant Staphylococcus Aureus Infections Among Thai Pediatric Patients, Pintip Suchartlikitwong, Nopphon Wuthinantiwong, Watsamon Jantarabenjakul, Noppadol Wacharachaisurapol, Jiratchaya Sophonphan, Tanittha Chatsuwan, Thanyawee Puthanakit

Chulalongkorn Medical Journal

Background While reductions in methicillin-resistant Staphylococcus aureus (MRSA) infections have been reported, vancomycin prescription rates have remained high.

Objectives We aimed to update trends in pediatric prevalence and antibiotic susceptibilities of MRSA infections.

Methods We conducted a retrospective study in patients aged S. aureus infections during 2016-2022 at a Thai tertiary-care hospital. MRSA was defined when resistant to cefoxitin or oxacillin MIC of >4 µg/mL. Patients with MRSA infections and their first isolates were classified into HA-MRSA or CA-MRSA based on surveillance definitions. Antibiotic susceptibilities were tested using the VITEK 2XL automated system and disk diffusion. The annual prevalence of …

Modeling The Effect Of Human Behavior On Disease Transmission, Katie Yan

Rose-Hulman Undergraduate Mathematics Journal

Many infectious disease models build upon the classic Susceptible-Infected-Recovered (SIR) model, a compartmental system that is used to simulate disease transmission in a population. The SIR model focuses on the transmission of disease but rarely includes behavioral or informational components that explore how disease perception influences transmission. In this paper, we propose a six-compartment behavioral SIR model that further segments the classic SIR system based on knowledge of information about the disease, and we explore how sharing information affects disease transmission. We designate two states as aware and unaware based on whether the relevant information is known by the population. …

In Vivo Evaluation Of Fatty Acid Loaded Chitosan Membranes For Pain Relief And Biofilm Associated Infection Prevention, Yogita Manasa Dintakurthi

Electronic Theses and Dissertations Archive

Infections are the leading cause of burn related deaths worldwide. These infections not only complicate micro-environment of a burn wound, but further obscure the wound due to the formation of biofilms at the wound site. Local drug delivery (LDD) has been a highly researched solution due to its advantages in locally treating and preventing infection while avoiding systemic side effects. LDD systems also have advantages for complex wounds, like burns. Chitosan is a natural polymer that is often used in these systems due to its biodegradability, biocompatibility and versatility. Previous research has suggested that short chain unsaturated fatty acids, for …

10-H2da Coating On Polyvinyl Chloride Catheter Biomaterials For Prevention Of Candida-Associated Urinary Tract Infections, Jermiah Tate

Electronic Theses and Dissertations Archive

Urinary catheters made of polyvinyl chloride (PVC) are susceptible to microbial biofilm formation. 10-hydroxy-2-decenoic acid (10-H2DA) is a dispersal signaling molecule that inhibits biofilm and planktonic growth of microorganisms. This study hypothesized that coating PVC with 10-H2DA would inhibit planktonic and biofilm-associated Candida albicans. Interactions of the PVC and 10-H2DA molecules were analyzed using Video Contact Angle (VCA), Fourier Transform Infrared (FTIR), and High-Performance Liquid Chromatography (HPLC). Successful coating of PVC with 10-H2DA was demonstrated through a significantly lowered contact angle and FTIR peaks in regions indicative of the 10-H2DA on the surface of PVC. Elution data displays a burst …

Can Safe Injection Sites Decrease The Incidence Of Infective Endocarditis?, Lindsay Kline

Summer Interdisciplinary Research Symposium

Objective: To discuss how safe injection sites (SIS) help to decrease the incidence of infective bacterial endocarditis in intravenous drug users. Methods: Six studies were chosen from online databases utilizing the search terms infective endocarditis, intravenous drug use, and SIS. They include a case-control study, retrospective cohort study, proposal, semi-structured interviews, narrative review, and cohort study. Results: SIS are imperative in the management and treatment of people who inject drugs (PWID) with infective endocarditis (IE). They help identify associated risk factors and provide a stable and safe environment for PWID as well as provide medical care. Conclusion: Patients who have …

Covid-19 Vaccination And The Development Of Type 1 Diabetes, Jordan Lachappelle

Summer Interdisciplinary Research Symposium

Objective: Incidence rates of new-onset Type 1 Diabetes Mellitus have been increasing over time, particularly following the COVID-19 pandemic. This research paper aims to investigate whether the COVID-19 vaccine is associated with a higher risk of developing Type 1 Diabetes.

Methods: Data was gathered through a literature review of five evidence-based studies sourced from online databases PubMed and Summon. Only studies with adults 18 years and older who were either vaccinated against or exposed to COVID-19, and without a prior diabetes diagnosis, were included. The outcome of interest was the incidence of Type 1 Diabetes after exposure to COVID-19 …

Impact Of A Pharmacist-Led Hcv Treatment Program At A Federally Qualified Health Center, Jerika T. Lam, Sharon Xavioer

Pharmacy Faculty Articles and Research

Pharmacists are key players who can help to eliminate the hepatitis C virus (HCV) epidemic in the United States. This pilot retrospective study evaluated the impact of a pharmacist-led HCV treatment program in a federally qualified health center (FQHC) primary care clinic setting. The primary outcome was to assess sustained virologic response (SVR) rates 12 weeks after patients were initiated and completed their oral direct acting antiviral (DAA) treatment regimens. Methods: This pilot retrospective study included historical analyses of patients who received DAA treatment in the pharmacist-led HCV treatment program in a FQHC clinic between 1 January 2019 and 31 …

The Anatomy Of Inequality: Medicine, Mourning, And Socioeconomic Status In Victorian England, Molly G. Decker

LSU Master's Theses

"The Anatomy of Inequality: Medicine, Mourning, and Socioeconomic Status in Victorian England," examines the historic relationships between socioeconomic inequality, death, and medical practice during the Victorian period, with specific ttention on London and surrounding areas. I argue that the extreme socioeconomic disparities of the time were deeply intertwined with the practices surrounding death, mourning, and medical care. The first chapter, "The Price of Sorrow," explores the elaborate mourning rituals and displays of status among the wealthy and upper to middle-class Victorians, detailing how these practices were not only expressions of grief but also conspicuous displays of social status and wealth. …

Hepatitis A Cases On The Rise And What Can Be Done About It, Dana Mccarney, Stephen Rawlings

Journal of Maine Medical Center

No abstract provided.

Differences In Active Ingredients Of White Chicory Leaves (Brassica Pekinensis L) As A Bio-Larvicidal Against Aedes Aegypti Larvae, Marlik Marlik, Dhea Stya Okta, Ngadino Ngadino, Demes Nurmayanti, Irwan Sulistio, Aries Prasetyo

Kesmas

Continuous chemical dengue control can cause vector resistance and environmental pollution. Developing natural larvicides (bio-larvicides) from plant toxins like white chicory, which can poison Aedes aegypti larvae, is necessary for a sustainable alternative. This study aimed to analyze differences in active ingredients in white chicory leaves (Brassica pekinensis L) as bio-larvicide against Aedes aegypti larvae. This study was a pure experiment using a post-test-only control design using 1,225 Aedes aegypti instar III larvae with extracts of alkaloid active ingredients, flavonoids, and concentrations of 0%, 24%, 34%, and 40% with 3 times replication. Data were analyzed using a probit test, one-way …

Do Apoe4, Malnutrition, And Long Covid-19 Compound The Risk Factors For Stroke In Adverse Environments?, Alexander Vasconcelos Buzaglo, Carlos Meton De Alencar Gadelha Vieira, Gabriella Cunha Vieira Ciurleo, Ludmila Belayev, Reinaldo B. Oriá

School of Medicine Faculty Publications

No abstract provided.