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Rwu Law Alumni Newsletter November 2024, Roger Williams University School Of Law

RWU Law

No abstract provided.

Variation In Provider Specialization Among 139 Non-Affiliated Real-World Data Contributors, Joshua Koni, Rose Reynolds, Janelle R. Noel-Macdonnell, Mark A. Hoffman

Posters

Oracle EHR Real-World Data (OERWD) is a national de-identified data set useful for observational findings across 139 non-affiliated healthcare systems. Data in OERWD is associated with a de-identified provider ID categorized and documented using National Uniform Claim Committee (NUCC) taxonomy codes. There are 2,421,948 providers in OERWD associated with both their specialty and contributing organization. We profile the data for overall distribution and co-occurrence of specialties, enabling research related to treatment patterns and outcomes.

Antibacterial And Antifungal Properties Of Hedyosmum Cuatrecazanum Occhioni Essential Oil: A Promising Natural Alternative Studied Using Neutrosophic Superhypersoft Sets, María Eugenia Lucena De Ustáriz, Francisco Javier Ustáriz-Fajardo, Adriana Monserrath Monge Moreno, Adriana Isabel Rodríguez Basantes, Lisbeth Josefina Reales Chacón, Rosa Elisa Cruz Tenempaguay, Verónica Paulina Cáceres Manzano, Nathaly Kassandra Moscoso Moreno

Neutrosophic Sets and Systems

Antimicrobial resistance is a global public health issue that, exacerbated by inappropriate antibiotic use, leads to reduced bactericidal effects, multidrug resistance, increased medical costs, prolonged hospital stays, and higher mortality rates. This study evaluates the antibacterial and antifungal activity of the es-sential oil of Hedyosmum cuatrecazanum Occhioni against various clinically relevant bacterial and fungal strains. The essential oil was extracted by hydrodistillation, yielding a 0.26% extract. Its components were characterized by gas chromatography coupled with mass spectrometry (GC-MS). The results demonstrate that the essential oil exhibits significant antibacterial activity, comparable to commercial antibiotics. Hedyosmum cuatrecazanum oil showed the highest antibacterial …

Effects Of Cultivars And Fungicides On Foliar Fungal Diseases And Fusarium Head Blight In Winter Wheat, Mahnoor Asif

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Foliar fungal diseases and Fusarium head blight (FHB) are among the major causes of significant yield losses in wheat production, particularly in Nebraska. Resistant cultivars and fungicide applications are common management strategies, but the overuse of fungicides has raised concerns about resistance in Fusarium graminearum populations in Nebraska. This study evaluated the effects of cultivar resistance, fungicide timing and their economic benefits. It also assessed the sensitivity of Nebraska isolates of F. graminearum and F. boothii to a triazole fungicide. In 2022 and 2024, 14 fungicide treatments and a control were arranged in a split-plot experimental design with …

Vol 4 November '24 Full Issue, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

Upside Down World, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

The Impact Of The Covid-19 Pandemic Among Latinos In Northwest Louisiana, Deborah G. Smith, Carolina O. Ochoa, Jillian L. Sandoz, Jennifer A. Deleon, Jason C. Hoosier, Corey D. Smith, Raimunda H.M. Macena

Journal of the Louisiana Public Health Association

No abstract provided.

Practices And Perceptions Of Uae Residents: Food Safety In Handling And Preparation Of Fish, Consumption, And Nutrition From Fish, Noof Ahmad Al Marzooqi

Theses

Background: UAE is uniquely located with an extensive seafront, which has led to the development of fishing and fisheries in the country. As a result, the UAE's diverse population has become one of the highest fish consumers among the Gulf countries. The high fish consumption in the UAE was a part of the traditional diet; however, a better understanding of UAE residents' practices and perceptions of fish food safety, fish preparation, and nutrition from fish consumption was needed. Objective: This study investigates food safety practices in handling and preparation of fish, consumption trends, and perceptions of nutrition from fish among …

Determining The Impact Of Lethal Temperature And Relative Humidity When Combined With Various Insecticide Classes Against A Bed Bug (Cimex Lectularius) Population., Bandana Shrestha

LSU Master's Theses

Common bed bugs (Cimex lectularius) are obligatory blood-feeding pests that have adapted well to survive in challenging environmental conditions. Known for their high tolerance to dehydration, low water loss, and high critical thermal maximum, they have become difficult to manage. Environmental factors, particularly temperature and humidity, play a significant role in their survival. However, with growing resistance to insecticides, integrated pest management (IPM) strategies are now essential for effective bed bug control. A key strategy in IPM involves combining insecticides with heat treatments. This method aims to overcome the limitations of heat treatment alone, as bed bugs may …

Evaluation Of Antibiofilm And Cytotoxic Activity Of Microalgae Isolated From Different Sites Of Betwata- Erbil/Iraq, Sewgil Saaduldeen Anwer, Ayad Kareem Ali, Nur Bozbeyoglu Kart, Dogukan Mutlu, Refika Ceyda Beram, Volkan Kuzucu, Sevki Arslan, Nazime Mercan Dogan

Baghdad Science Journal

This in vivo study is aimed to assess the antibiofilm and cytotoxic potential of selected microalgae isolates. Different concentration of microalgal isolates used for each of antibiofilm and cytotoxic studies. A total extract of 10 μL MTT was added to each well with LB broth, plates were read using microtiter plate spectrophotometer at 490 nm and 630 nm, respectively. The cell viability was determined in CCD-18℃ cells (3x10^3 cells/well) by MTT assay at 590 nm. The microalgae isolates showed antibiofilm affect after 48 hrs on Pseudomonas aeruginosa PA01 and this effect was observed to be higher than those of S. …

But, It's Just A Uti, Gillian Long

Posters

IgA Vasculitis is a commonly seen presentation in the pediatric population. The constellation of symptoms typically includes purpuric rash, joint pain, abdominal pain and hematuria. This 12 year old female was seen by her pediatrician for rash on her legs, shortness of breath, cough and night sweats that all started around 2 months ago. Additionally, a 25 pound weight loss was noted over the past year. The rash appeared as nonblanching purpura on her lower extremities, lending suspicion to IgA Vasculitis. She was first treated for UTI with cefuroxime, and then treated with steroids. Urinalysis showed persistent hematuria and she …

Natural Panola Mountain Ehrlichia Infections In Cattle In A Longitudinal Study Of Angus Beef Calves, Cierra Briggs, Drew Casey, Anna Grace Deakins, Jeremy G. Powell, Kelly Loftin, Emily G. Mcdermott

Entomology and Plant Pathology Faculty Publications and Presentations

Panola Mountain Ehrlichia (PME) is an emerging zoonotic pathogen, transmitted by Amblyomma americanum ticks in the southeastern United States. It is closely related to Ehrlichia ruminantium, the causative agent of heartwater disease. Heartwater disease is an often-fatal illness of ruminant livestock present in Africa and the Caribbean. The taxonomic relationship between PME and E. ruminantium has raised concerns about the pathogenicity of PME in livestock. To determine whether cattle could be naturally infected with PME in an endemic area, we conducted a one-year longitudinal study of Angus-breed beef calves in Fayetteville, Arkansas. One hundred seventy-seven calves born between September …

Clostridium Septicum: Cause Of Gas Gangrene In The Upper Extremity Leading To Proximal Trans-Humeral Amputation, A Review Of Clostridium Septicum., Mark Lagreca, Denise Chen, Patrick Frick, Genoveffa Morway, Austin Egger, Julia Mayberry

Orthopedic Surgery Resident Research

INTRODUCTION: Gas gangrene is a rare, often lethal infection of soft tissue that is commonly associated with the Clostridial species due to penetrating injuries. Case reports of spontaneous atraumatic gas gangrene due to the Clostridium septicum species are exceedingly rare. Atraumatic C. septicum is notably related to bowel pathologies, immunodeficiencies, and individuals with vascular insufficiency. The rapid progression of Clostridium myonecrosis contributes to its high mortality rates.

CASE REPORT: The authors report a case of a 71-year-old right-hand-dominant female who developed fulminant atraumatic left forearm pain and swelling. The patient was indicated for emergent irrigation and debridement (I&D) of the …

Staggering Stink Bugs: Autotomy Affects Stability And Locomotor Performance In Halymorpha Halys, Lilian Jubb

Longwood Senior Theses

Autotomy, the voluntary loss of a limb, is a common predator evasion strategy in arthropods. Considerable research on autotomy has focused on arachnids, which have developed morphological compensations to manage the stability challenges posed by limb loss, as explained by the extra leg hypothesis. However, studies in insects are unclear about such a mechanism. In hexapods, a tripod gait means that losing any one limb disrupts one of the tripod stances. It is not fully understood how insects compensate for the resulting loss of stability and potential performance effects. We hypothesize that insects exhibit neural plasticity, allowing them to adjust …

English For Specific Purposes In The Medical Sciences To Strengthen The Professional Profile Of The Higher Education Medicine Student: A Knowledge Representation Using Superhypersoft Sets, Oswaldo Edison García Brito, Andrea Sofía Ribadeneira Vacacela, Carmen Hortensia Sánchez Burneo, Mónica Cecilia Jimbo Galarza

Neutrosophic Sets and Systems

The English language is an important added value for the professional profile of students in all higher education courses due to the demands of the current century, in which mastering more than one lan-guage is undoubtedly one of the preponderant skills to access better and more opportunities within the workplace, especially in careers such as medicine. Therefore, the curricular design and the implementa-tion of a program focused on the development of the linguistic skills of the future health professional is pertinent and necessary to strengthen their professional profile; not only in the discourse at the level of talks, congresses, training, …

Mechanisms Of Extracellular Vesicle Uptake And Implications For The Design Of Cancer Therapeutics, Stephanie R. Jackson Cullison, Joseph P. Flemming, Kubra Karagoz, Peter J. Wermuth, Mỹ G. Mahoney

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

The translation of pre-clinical anti-cancer therapies to regulatory approval has been promising, but slower than hoped. While innovative and effective treatments continue to achieve or seek approval, setbacks are often attributed to a lack of efficacy, failure to achieve clinical endpoints, and dose-limiting toxicities. Successful efforts have been characterized by the development of therapeutics designed to specifically deliver optimal and effective dosing to tumour cells while minimizing off-target toxicity. Much effort has been devoted to the rational design and application of synthetic nanoparticles to serve as targeted therapeutic delivery vehicles. Several challenges to the successful application of this modality as …

Enterococcus Faecium: Evolution, Adaptation, Pathogenesis And Emerging Therapeutics, Yahan Wei, Dennise Palacios Araya, Kelli L. Palmer

School of Podiatric Medicine Publications

The opportunistic pathogen Enterococcus faecium colonizes humans and a wide range of animals, endures numerous stresses, resists antibiotic treatment and stubbornly persists in clinical environments. The widespread application of antibiotics in hospitals and agriculture has contributed to the emergence of vancomycin-resistant E. faecium, which causes many hospital-acquired infections. In this Review, we explore recent discoveries about the evolutionary history, the environmental adaptation and the colonization and dissemination mechanisms of E. faecium and vancomycin-resistant E. faecium. These studies provide critical insights necessary for developing novel preventive and therapeutic approaches against vancomycin-resistant E. faecium and also reveal the intricate interrelationships …

Conceptions Of Latinos And Latinas About The Grieving Process And Associate Concepts Of Dying, Death, Bereavement, And Loss: A Covid-19-Post-Pandemic Case Study, Rosario Garcia Ortiz

Dissertations

The purpose of this study was to recognize the grieving process and the related concepts of Latinos who lost a loved one to the COVID-19 pandemic. Death and dying have been studied in the United States, with limited studies focusing on the Latino culture. The COVID-19 pandemic was a devastating experience for the world and continues to be studied for understanding and lessons in the aftermath. This research included four participants from the Latino culture who lost a loved one during the COVID-19 pandemic. An inductive approach and data analysis were used to form theoretical constructs. Three main categories were …

Diaphragmatic Myopathy Associated With Dual Immune Checkpoint Inhibitors In A Patient With Renal Cell Carcinoma, Jeremy R Walder, Saadia A Faiz, Sudhakar Tummala, Shiao-Pei Weathers, Nicolas L Palaskas, Maryam Buni, Ajay Sheshadri, Lara Bashoura

Faculty, Staff and Student Publications

Immune-related adverse events (irAEs) have become increasingly prevalent with immune checkpoint inhibitor (ICI) cancer treatment. We present a 79-year-old man with metastatic renal cell carcinoma who developed shortness of breath and hypercapnic respiratory insufficiency after his first cycle of nivolumab and ipilimumab. Laboratory data showed elevated creatinine kinase, troponins, and transaminases. Computed tomography of the chest demonstrated bilateral lower lobe atelectasis. Heart catheterization and endomyocardial biopsy were unremarkable. Electromyogram (EMG) and nerve conduction studies (NCS) of the limb muscles revealed mild diffuse myopathy, normal sensory nerve conductions, and low-amplitude motor responses. Subsequent diaphragmatic EMG and NCS demonstrated severe myopathy. ICI-mediated …

Advancing Crispr-Based Solutions For Covid-19 Diagnosis And Therapeutics, Roaa Hadi, Abhishek Poddar, Shivakuma Sonnaila, Venkata Suryanarayana Murthy Bhavaraju, Shilpi Agrawal

Chemistry & Biochemistry Faculty Publications and Presentations

Since the onset of the COVID-19 pandemic, a variety of diagnostic approaches, including RT-qPCR, RAPID, and LFA, have been adopted, with RT-qPCR emerging as the gold standard. However, a significant challenge in COVID-19 diagnostics is the wide range of symptoms presented by patients, necessitating early and accurate diagnosis for effective management. Although RT-qPCR is a precise molecular technique, it is not immune to false-negative results. In contrast, CRISPR-based detection methods for SARS-CoV-2 offer several advantages: they are cost-effective, time-efficient, highly sensitive, and specific, and they do not require sophisticated instruments. These methods also show promise for scalability, enabling diagnostic tests. …

Evidence Of Human Bourbon Virus Infections, North Carolina, Usa, Diana L Zychowski, Gayan Bamunuarachchi, Scott P Commins, Ross M Boyce, Adrianus C M Boon

2020-Current year OA Pubs

Bourbon virus is a tickborne virus that can cause human disease. Cases have been reported in Kansas, Oklahoma, and Missouri, USA. We identified Bourbon virus-specific neutralizing antibodies in patients from North Carolina. Bourbon virus infections are likely more common than previously thought, highlighting the need for improved diagnostics and surveillance.

Electron-Beam-Killed Staphylococcus Vaccine Reduced Lameness In Broiler Chickens, Anna L.F.V. Assumpcao, Komala Arsi, Andi Asnayanti, Khawla Alharbi, Anh Dang Trieu Do, Quentin D. Read, Ruvindu Perera, Abdulkarim Shwani, Amer Abdullah Hasan, Suresh D. Pillai, Robin C. Anderson, Annie M. Donoghue, Douglas D. Rhoads, Palmy R.R. Jesudhasan, Adnan A. Alrubaye

Poultry Science Faculty Publications and Presentations

Broiler chicken lameness caused by bacterial chondronecrosis with osteomyelitis (BCO) is presently amongst the most important economic and animal welfare issues faced by the poultry industry, and the estimated economic loss is around USD 150 million. BCO lameness is associated with multiple opportunistic bacterial pathogens inhabiting the respiratory and gastrointestinal tracts. In cases of immune deficiency resulting from stress, injury, or inflammation of the tissue, opportunistic pathogens, mainly Staphylococcus spp., can infiltrate the respiratory or gastrointestinal mucosa and migrate through the bloodstream to eventually colonize the growth plates of long bones, causing necrosis that leads to lameness. This is the …

Improving Socioeconomic Conditions For Ghanaian Fishers On Flagged Vessels : Policy Recommendations For The Fishing Industry, Robert Nyarkoh

World Maritime University Dissertations

No abstract provided.

Solid Waste Management Practices And The Role Of Public Perception In West Point, Monrovia, Liberia, Lucy Garmai Varnie

World Maritime University Dissertations

No abstract provided.

Dean's Research Newsletter, November 2024, Neil W. Schluger

SOM Dean's Research Newsletter

No abstract provided.

Multidisciplinary Amputation Prevention At The Debakey Va Hospital: Our First Decade, Neal R Barshes, Aimee D Garcia, Cezarina Mindru, Maria Rodriguez-Barradas, Panos Kougias, David M Green, Samir S Awad

Faculty, Staff and Students Publications

BACKGROUND: In 2011, the Veterans Health Administration (VHA) undertook multidisciplinary efforts to improve care for patients with nonhealing foot ulcers and reduce leg amputation rates. This article examines the impact of interdisciplinary care for amputation prevention in the VHA.

METHODS: The VHA patient population was characterized using internal registries. Texas hospital admission data were used to identify sex and zip-code matched cohorts. VHA provided data on national and local frequencies of various amputations and the number of patients with diabetes.

RESULTS: Compared to matched nonveteran patients, veterans treated at VHA hospitals were older and more often self-identified as Black. They …

Ga2len Anacare Consensus Statement: Potential Of Omalizumab In Food Allergy Management, Torsten Zuberbier, Antonella Muraro, Ulugbek Nurmatov, Stefania Arasi, Katarina Stevanovic, Aikaterini Anagnostou, Roberta Bonaguro, Sharon Chinthrajah, Gideon Lack, Alessandro Fiocchi, Thuy-My Le, Paul Turner, Montserrat Alvaro Lozano, Elizabeth Angier, Simona Barni, Phillippe Bégin, Barbara Ballmer-Weber, Victoria Cardona, Carsten Bindslev-Jensen, Antonella Cianferoni, Nicolette De Jong, Debra De Silva, Antoine Deschildre, Audrey Dunn Galvin, Motohiro Ebisawa, David M Fleischer, Jennifer Gerdts, Mattia Giovannini, Josefine Gradman, Susanne Halken, Syed Hasan Arshad, Ekaterina Khaleva, Susanne Lau, Richard Loh, Mika J Mäkelä, Mary Jane Marchisotto, Laura Morandini, Charlotte G Mortz, Caroline Nilsson, Anna Nowak-Wegrzyn, Marcia Podestà, Lars K Poulsen, Graham Roberts, Pablo Rodríguez Del Río, Hugh A Sampson, Angel Sánchez, Sabine Schnadt, Peter K Smith, Hania Szajewska, Natasa Teovska Mitrevska, Alice Toniolo, Carina Venter, Amena Warner, Gary W K Wong, Robert Wood, Margitta Worm

Faculty, Staff and Students Publications

Immunoglobulin E (IgE)‐mediated food allergies are the most common type of food allergy, often causing rapid symptoms after exposure to allergens posing a serious health risk and a high impact on patient's and caregiver's quality of life. Omalizumab, a humanized anti‐IgE monoclonal antibody, reduces allergic reactions by binding to circulating IgE. Omalizumab has been successfully used in allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic urticaria, and was recently approved for treating IgE‐mediated food allergies by the US Food and Drug Administration (FDA). This GA2LEN ANACARE Consensus Statement presents our position on the use of omalizumab for treating IgE‐mediated …

Antibiotic-Associated Neutropenia Is Marked By The Depletion Of Intestinal Lachnospiraceae And Associated Metabolites In Pediatric Patients, Josaura Fernandez-Sanchez, Rachel Rodgers, Arushana A Maknojia, Nusrat Shaikh, Hannah Yan, Marlyd E Mejia, Hope Hendricks, Robert R Jenq, Pavan Reddy, Ritu Banerjee, Jeremy M Schraw, Megan T Baldridge, Katherine Y King

Faculty, Staff and Student Publications

Prolonged antibiotic exposure causes dangerous hematologic side effects, including neutropenia, in up to 34% of patients. Murine studies established a link between the intestinal microbiota and hematopoiesis. To identify factors that predispose to neutropenia in pediatric patients, we evaluated changes in microbiota‐derived metabolites and intestinal microbiota composition after prolonged courses of antibiotics. In this multi‐center study, patients with infections requiring anticipated antibiotic treatment of two or more weeks were enrolled. Stool samples were obtained at the start and completion of antibiotics or at neutropenia onset (prospective arm). Some patients were enrolled in a retrospective arm in which a stool sample …

A Comparison Of The Diagnostic Capability Of Kato-Katz And Real-Time Pcr For The Assessment Of Treatment Efficacy Of Ivermectin And Albendazole Combination Against T Trichiura Infections, Gabriela Matamoros, Ana Sanchez, Ruben Cimino, Alejandro Krolewiecki, Rojelio Mejia

Faculty, Staff and Students Publications

BACKGROUND: Trichuris trichiura is humans' second most prevalent soil-transmitted helminth (STH) infection after Ascaris lumbricoides, affecting approximately 460 million people worldwide. Despite its sub-optimal sensitivity, especially in low prevalence and infection intensity settings, the modified Kato-Katz (K-K) is still recommended as a diagnostic method by the World Health organization (WHO) guidelines.

METHODOLOGY/PRINCIPAL FINDINGS: Within a randomized clinical trial (RCT) comprising four treatment arms with two different anthelmintics, the present study reports an important secondary research objective to determine the diagnostic agreement between K-K and real-time PCR evaluating treatment efficacy against T. trichiura. The parasitological results were analyzed, including cure rates …

Automated Electronic Health Record Data Extraction And Curation Using Extractehr, Tamara P Miller, Kelly D Getz, Edward Krause, Yun Gun Jo, Sandhya Charapala, M Monica Gramatages, Karen Rabin, Michael E Scheurer, Jennifer J Wilkes, Brian T Fisher, Richard Aplenc

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Although the potential transformative effect of electronic health record (EHR) data on clinical research in adult patient populations has been very extensively discussed, the effect on pediatric oncology research has been limited. Multiple factors contribute to this more limited effect, including the paucity of pediatric cancer cases in commercial EHR-derived cancer data sets and phenotypic case identification challenges in pediatric federated EHR data.

Methods: The ExtractEHR software package was initially developed as a tool to improve clinical trial adverse event reporting but has expanded its use cases to include the development of multisite EHR data sets and the support …