Digital Commons Network^™

Closing The Loop: Solar-Powered Vermicomposter, Isabela Ibrahim , '25, Lindsey Turner , '25

Senior Theses, Projects, and Awards

Organic waste is oftentimes poorly managed and directed to landfill and incineration, as more sustainable alternatives such as traditional composting are not always accessible. Swarthmore College has a robust composting partnership offsite, however, it does not leverage avenues for waste stream circularity on campus to its full potential. Vermicomposting, composting that incorporates earthworms (Eisenia fetida), consists of a method to achieve small-scale and accessible composting. The goal of this project was to create an on-campus, low-maintenance, replicable, and sustainable vermicomposter to efficiently repurpose food waste from Swarthmore’s dining hall into nutrient-rich soil amendments for the adjacent Our Food Garden. …

Modeling Droplet Levitation Over A Heated Liquid Surface, Jacob E. Davis

Mathematics Theses and Dissertations

Research into the interactions between droplets and liquid surfaces is of importance for a number of practical applications. These applications range from spray cooling techniques in engineering, to infectious disease transmission, to the distribution of aerosolized pharmaceuticals and various challenges in particle transport in multiphase flows. In this study, we focus on the dynamics of a slowly condensing droplet, suspended above an evaporating liquid layer. The key objective of the present study is to formulate comprehensive mathematical models that describe the phenomena of diffusion and heat transfer occurring within this system. Using this, we model the flow around the droplet …

Comparative Study Of Pregnancy Risks In Different Maternal Age Groups, Amala Sunder, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Nayla Jamal Bushaqer, Basma Darwish, Nawal Dayoub

Saudi Medical Journal

ABSTRACT Objectives: To evaluate and compare pregnancy complications associated with varying maternal age groups. Methods: A retrospective analysis of singleton pregnancy outcomes at Bahrain Defense Force Hospital from January to December 2022. The study population was divided into 4 age groups: <25 years, 25-29 years, 30-34 years, and ≥35 years. Data on demographics, maternal and fetal characteristics were collected, and statistical significance was set at p <0.05. Univariate logistic regression was performed to analyze maternal and neonatal outcomes, adjusting for maternal factors. Results: The study included 2,972 women aged 17-55. Significant associations were found between maternal age and outcomes. Body mass index (BMI) was significantly linked to age ( p <0.01), with younger women having lower BMI. Gestational diabetes mellitus (GDM) was more common in women ≥35 years (11.5%) vs. those <25 years (6.6%, p =0.027). Intrauterine growth restriction (IUGR) was more prevalent in the <25 years age group ( p =0.041).Logistic regression showed women 30-34 years had a lower risk of GDM compared to 25-29 years (odds ratio [OR]: 0.544, CI: 0.365-0.811), and women <25 years had a higher risk of preterm delivery (OR: 1.365, CI: 1.015-1.837). Conclusion: Maternal age is an independent risk factor for various adverse outcomes. Younger women (<25) are at higher risk for preterm delivery and IUGR, while older women (≥35) have higher rates of GDM.

Variation In Blood Culture Testing For Three Common Infections, Smit Shah, Jennifer Goldman, Matt Hall, Jillian Cotter, Samantha A. House, Matthew J. Molloy, Michelle Polich, Michael J. Steiner, John R. Stephens, Michael J. Tchou, Ronald J. Teufel Ii, Irma Ugalde, Andrew Yu, Jessica L. Markham

Presentations

Background: Routine blood culture (BC) testing in uncomplicated community-acquired pneumonia (CAP), skin and soft tissue infections (SSTI), and urinary tract infections (UTI) has demonstrated low clinical utility. Objectives: To evaluate hospital-level BC testing trends and their association with clinical outcome differences for children hospitalized with CAP, SSTI, and UTI. Methods: This retrospective cohort study used the Pediatric Health Information System database to identify hospitalizations of children aged 3 months-18 years admitted with CAP, SSTI, or UTI from 2016-2023. We excluded patients with complicated infections, medical complexity, ICU admission, or length of stay (LOS) >7 days. Hospital-level BC testing rates were …

Patterns Of Antibiotic Resistance In Uropathogens Isolated From Pediatric Patients: A Multicenter Study, Zeyad A. Almatroudi, Abdullah M. Almazrou, Abdullah H. Aljomoai, Zaid M. Alsulami, Abdulaziz M. Alotaibi, Abdulmohsen A. Almutairi, Aiman El-Saed, Faisal A. Alsehli, Majid M. Alshamrani

Saudi Medical Journal

ABSTRACT Objectives: To evaluate the antibiotic resistance patterns in common uropathogens isolated from pediatric patients. Methods: This was a retrospective chart review on the uropathogens causing first-time, community-acquired, symptomatic urinary tract infection (UTI). The data for this study was collected from one tertiary care hospital and 4 primary care centers in Riyadh, Saudi Arabia, with data spanning from 2017-2022. Diagnosis of UTIs was in line with the guidelines of the American Academy of Pediatrics. Results: Isolates were gathered from 610 patients, 101 (16.6%) of whom were male and 509 (83.4%) were female. The 3 most common species isolated were Escherichia …

Tuberculosis Screening In The Ambulatory Setting, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Quadratic Stochastic Processes: Algebraic Structures And Their Applications, Taimun Saleh Qaisar

Dissertations

This research focuses on the algebraic structures of the Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠). In this work, we first study 𝜉𝑎- Quadratic Stochastic Operators (𝑄𝑆𝑂𝑠) linked to the partition P3. We simultaneously discuss the dynamics of the obtained 𝑄𝑆𝑂𝑠. Moreover, algebraic structure of the associated genetic algebra is studied. Further, we build Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠) using the given Markov processes. Consequently, we obtain an ordinary differential equation for the resultant Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠). Besides, we apply the solution of this ordinary differential equation for the option pricing problem. Thereafter, we construct Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠) in three-dimensional space by …

Management Of Cardiovascular Implantable Electronic Device Infection Utilizing A Multidisciplinary Team, Evan Hall, Bennett Collis, Talal Alnabelsi, Chloe Cao, Meredith Johnson, John Gurley, Luke Strnad, Hassan Reda, Tessa London, Erinn Ogburn, Michael Sekela, Bobbi Jo Stoner, Sami El-Dalati

Surgery Faculty Publications

Background. Significant numbers of cardiac implantable electronic devices are placed in the United States, and infection can be a severe consequence of implantation. Despite guideline recommendations and data demonstrating that lead extraction improves mortality for patients with device infection, rates of lead removal are lower than guideline recommendations. We report the outcomes associated with management of suspected cardiac implantable electronic device infections by a multidisciplinary team. Methods. Patient cases were identified from an institutional multidisciplinary endocarditis team registry in a single-center retrospective study. Demographic, treatment, and outcomes data were recorded by study investigators. Results. Between September 7, 2021, and February …

From Relapse To Restoration: Insights Into The Immunopathology Of Bacterial Vaginosis (Bv) In Women Of Reproductive Age, Nhi To, Ms

Student Papers, Posters & Projects

Bacterial vaginosis (BV) has been a subject of study for decades, yet its complex pathogenesis remains poorly understood. BV affects most women of reproductive age, with significant associations to gynecological and obstetric complications. A deeper understanding of the complicated host-microbiota dynamic is crucial for advancing treatment options, as BV continues to pose challenges in effective management. This review aims to explore the current research on vaginal microbiota as well as potential mechanisms of BV-associated bacteria (BVAB) and their interaction with the host immune system, altogether sheds light on the complex interplay within the human reproductive tract. While Lactobacillus-dominant communities support …

Ccr7 Regulated Mechanisms That Limit The Adaptive Immune Response, Jaisel Amilcar Cervantes

Open Access Theses & Dissertations

C-C chemokine receptor 7 (CCR7) is critical in guiding T cell migration within the thymus and peripheral lymphoid tissues, shaping the adaptive immune response by promoting central tolerance and regulating immune homeostasis. Although its role in lymphocyte trafficking is well established, the molecular mechanisms by which CCR7 influences thymocyte development and T cell receptor (TCR) repertoire formation remain less understood. This study examines how CCR7 deficiency impacts thymic selection, TCR diversity, and the signaling events that shape repertoire restriction. Using a homozygously deleted CCR7 murine model, we found that the absence of CCR7 results in a less restricted TCR repertoire …

Medical Professionals' Perceptions Of Healthcare Artificial Intelligence, Falon M. Costigan

Electronic Theses and Dissertations

This study examined whether medical professionals across different levels of expertise show differences in their perceptions of healthcare artificial intelligence (AI). Specifically, the researcher hypothesized that participants with more expertise and experience would have greater negative perceptions associated with AI in healthcare compared to participants with a lower expertise level. Participants completed a questionnaire evaluating their perceptions of healthcare AI across four components: long-term negative consequences of AI, need for AI safeguards, positive perceptions of AI, and AI control. Participants also completed demographic questions evaluating participants' age, sex, ethnicity, years working in a healthcare setting, medical …

An Exploratory Study Of Disclosure Of X-Linked Conditions Between Mothers And Daughters, Madge Isabella Stuhlreyer

Theses and Dissertations

Carriers of X-linked conditions, both asymptomatic and symptomatic, face unique challenges regarding their experiences navigating the healthcare system and understanding implications of their carrier status. Studies show that mothers are known to be the main communicators of genetic information within their families, but in families affected with X-linked conditions, communication between mothers and daughters are hindered by factors such as lack of knowledge about the condition and reproductive implications, lack of emotional support, anxiety, and uncertainty about how to initiate these conversations. The purpose of this study was to explore the motivations behind mothers' decisions to initiate conversations with their …

Silver Nanoparticles And Vanillin Can Inhibit Collagenase Activities Of Serratia Marcescens, Elaine Vanterpool, Mya St. Louis, Josel Bryant, Kennedi Ewan, Taylor Hall, Leah Marcelle, Mayah Seal

Student Posters

Serratia marcescens is a gram-negative, disease-causing agent that belongs to the Enterobacteriaceae family. This rod-shaped microbe causes many infectious diseases such as urinary and respiratory infections, wound infections, and peritonitis, which can result in fatal bacteremia. Collagenase is an enzyme that breaks down collagen, while also playing a key role in the extracellular matrix. Collagenase uses zinc to operate that helps it break down the peptide bonds in collagen. Testing Agents ❖ Metronidazole is an antimicrobial drug used to treat infections caused by different anaerobic bacteria, such as infections in the blood, liver, bones, joints, and meninges. ❖ Vanillin is …

The Effect Of Grape Seed Extract Against The Formation Of S.Aureus Biofilms In A Clinical Setting, Srestha Samaddar

Senior Theses

The rise of antibiotic-resistant bacterial infections, particularly those caused by Staphylococcus aureus, poses a serious threat to public health and clinical care. A major contributor to the persistence of these infections is the formation of bacterial biofilms, structured communities that protect S. aureus from antibiotics and immune responses, especially on surgical sites and medical devices. As conventional treatments become less effective, interest in alternative, natural antimicrobial agents has increased, due to public dissatisfaction with conventional medicine and a growing trust in complementary and alternative medicine. Grape seed extract (GSE), a polyphenol-rich byproduct of winemaking, has emerged as a promising candidate …

Estimation Of Therapeutic Threshold For Tuberculosis Using Adapted Nominal Group Technique And Clinical Vignettes In Clinical And Community Settings In Southern Africa, Alfred Kipyegon Keter, Alastair Van Heerden, Tom Decroo, Tom Boyles, Shannon Bosman, Thandanani Madonsela, Lindani Innocent Msimango, Lenika Naiken, Carlos Kiyan, Mashaete Kamele

Population Health, East Africa

Background: When confronted with diagnostic uncertainty and a decision on whether to start treatment or not, clinicians consider the potential harm and benefit of offering versus withholding treatment. Treatment can be offered if the probability of tuberculosis (TB) in the patient is above the “therapeutic threshold” (ThT): the probability of disease at which the expected utility of treating and not treating is the same. We estimated ThT for TB in clinical and community settings in Southern Africa using two methods: an adapted nominal group technique (aNGT), and decisions made based on clinical vignettes (CVs).

Methods: We enrolled health …

Cytokine Storms In Covid-19, Hemophagocytic Lymphohistiocytosis, And Car-T Therapy, James P Long, Rishab Prakash, Paul Edelkamp, Mark Knafl, Anath C Lionel, Ranjit Nair, Sairah Ahmed, Paolo Strati, Luis E Malpica Castillo, Ajlan Al-Zaki, Kelly Chien, Dai Chihara, Jason Westin, Fareed Khawaja, Loretta J Nastoupil, Victor Mulanovich, Andrew Futreal, Scott E Woodman, Naval G Daver, Christopher R Flowers, Sattva Neelapu, Joanna-Grace Manzano, Swaminathan P Iyer

Faculty, Staff and Student Publications

Importance: Cytokine storm (CS) is a hyperinflammatory syndrome causing multiorgan dysfunction and high mortality, especially in patients with malignant hematologic neoplasms. Triggers include malignant neoplasm-associated hemophagocytic lymphohistiocytosis (MN-HLH), cytokine release syndrome from chimeric antigen receptor T-cell therapy (CAR-T CRS), and COVID-19, but the underlying mechanisms of inflammation and their impact on outcomes are poorly understood.

Objective: To delineate the inflammatory patterns characterizing different CS etiologies and their association with clinical outcomes.

Design, setting, and participants: This retrospective cohort study was conducted at the MD Anderson Cancer Center in Houston, Texas, between March 1, 2020, and November 20, 2022, using the …

A Masque Of Red Death: The Fda's "Individual Risk-Based" Blood Donor Final Guidance Report Is A Poorly Constructed Facade Covering Continued Animus Toward Queer Men, Gerald Dryden

Cardozo Journal of Equal Rights & Social Justice

The note argues that the FDA's blood donation guidelines discriminatorily target queer men, perpetuating stigma and failing to align with contemporary science. These guidelines, while aiming to protect blood recipients, are unconstitutional and not tailored to avoid discrimination, thus requiring revision to reflect current scientific understanding and eliminate bias.

Spatial Quantile Autoregressive Model: A Review, Sawsan Qassim Hadi, Omar Abdulmohsin Ali

Journal of Economics and Administrative Sciences

This paper is specifically a detailed review of the Spatial Quantile Autoregressive (SARQR) model that refers to the incorporation of quantile regression models into spatial autoregressive models to facilitate an improved analysis of the characteristics of spatially dependent data. The relevance of SARQR is emphasized in most applications, including but not limited to the fields that might need the study of spatial variation and dependencies. In particular, it looks at literature dated from 1971 and 2024 and shows the extent to which SARQR had already been applied previously in other disciplines such as economics, real estate, environmental science, and epidemiology. …

Targeting Malaria Using Rts,S/As01 Liposome Based Therapy In Combination With Cryptolepis Sanguinolenta, Michelle Villacorta Del Castillo

Selected Honors Theses

Malaria has shown to be a threatening disease to half of the population of the world, with currently 241 million cases reported. Malaria treatments have yet to be completely effective due to their ability and resistance to antimalarial drugs Plasmodium falciparum has developed, making it challenging to help treat this disease. RTS, S/AS01 has been shown to act on the pre-erythrocytic stage of malaria, targeting the circumsporozoite protein of Plasmodium falciparum expressed by the malaria parasite during this stage. At the same time, Cryptolepsis Sanguinolenta has been shown to have 90% inhibition of Plasmodium falciparum K1 growth. They have both …

Fungal Infections In People Who Use Drugs, Jose Portugal Gonzales, Luis Ostrosky-Zeichner

Faculty, Staff and Student Publications

Illicit drug use in the United States continues to rise, alongside an increasing number of severe infections associated with drug use. Surveillance studies report that 28%–34% of candidemia cases are linked to intravenous drug use, with Candida albicans being the most commonly isolated species, followed by Candida parapsilosis and Candida glabrata. Marijuana use is associated with lung infections caused by Aspergillus and the Mucorales, showing a 3.5-fold increased risk of mold infections and a 2.2-fold increased risk for other fungal infections. Intravenous drug use also presents a recognized risk factor for Aspergillus and Mucorales infections. Additionally, substances like …

Prediction Of Hepatitis C Virus Perinatal Transmission In Pregnant Individuals With Hepatitis C Virus Infection, Grecio J Sandoval, George R Saade, Brenna L Hughes, Rebecca G Clifton, Uma M Reddy, Anna Bartholomew, Ashley Salazar, Edward K Chien, Alan T N Tita, John M Thorp, Torri D Metz, Ronald J Wapner, Vishakha Sabharwal, Hyagriv N Simhan, Geeta K Swamy, Kent D Heyborne, Baha M Sibai, William A Grobman, Yasser Y El-Sayed, Brian M Casey, Samuel Parry, George A Macones, Mona Prasad

Faculty, Staff and Student Publications

Our objective was to develop a prediction model for hepatitis C virus (HCV) infection perinatal transmission to improve triage for neonatal follow-up. This was a secondary analysis of HCV antibody-positive participants who were enrolled in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network multicenter observational study of HCV infection in pregnancy. Among 432 participants, the perinatal transmission rate was 6.0% (95% CI, 4.0-8.7%). The prediction model was developed and included two factors: maternal HCV RNA titer greater than 10 6 international units/mL and having had any antepartum bleeding. Using this model, the …

Haemato-Urological Profile And Asymptomatic Urinary Tract Infection In Ghanaian Steady-State Sickle Cell Disease Patients: A Case-Control Study, Stephen Twumasi, Richard Owusu Ansah, Samuel Essien-Baidoo, Laud Anthony W. Basing, Alexander Yaw Debrah, Enoch Odame Anto, Allwell Adofo Ayirebi, Rebecca Asiamah-Broni, Waldemer Attivor, Eric Twum Ameyaw, Gabriel Addai Manu, Edward Afriyie, Thomas Kwabena Gyampomah, Joseph Nkrumah Opoku, Prince Kwadwo Amoafo, Samuel Kelvin Owusu, Vincent Akwai, Matthew Talmang, Amos Mensah, Isaac Kusi-Amponsah, Angela Opoku, Lilian Antwi Boateng

Research outputs 2022 to 2026

Background and Aims: Due to the reduction in immunity caused by auto-splenectomy and the consequent opsonic antibody shortage, patients with SCD are more susceptible to encapsulated organism infections, especially asymptomatic urinary tract infection (ASM-UTI). This study investigated the prevalence of ASM-UTI and compared urine and hematology parameters among SCD patients in Ghana to their healthy counterparts. Methods: In this study, 104 SCD participants (cases) and 80 non-SCD (HbAA) controls were recruited. Participants' information was thoroughly documented using a well-structured questionnaire and patient case records. To achieve the study's aims, a mid-stream urine in a cleaned dry aseptic urine capped container …

Hybrid Treatment Method Of Biofiltration Preceded With Advanced Oxidation Process For The Removal Of Emerging Contaminants From The Wastewater Treatment Plant Effluent, Anjali Mohan Payathuparambil

Theses

The global demand for potable quality water has been on a continuous rise. Consequently, water reuse is now considered as an alternative to significantly expand supplies of freshwater in communities facing water shortages. Most of the conventional wastewater treatment plants (WWTP) are not efficient in the removal of emerging contaminants from the water, which will cause serious issues to the environment, human and animal life. This research investigated the possibilities of treating wastewater for reuse. First, the feasibility of utilizing a biofiltration system without pre-treatment for removing emerging contaminants from the WWTP effluent was investigated. Two types of biofilter media- …

The Cellular Trafficking And Targeting Of Angiotensin-Converting-Enzyme-2 (Ace2) And Neutral-Amino-Acid-Transporter (B0at1) Variants: Implications For The Pathogenesis Of Associated Diseases And Therapy, Nesreen Fayyad Alkhofash

Dissertations

Angiotensin-converting enzyme 2 (ACE2) and the neutral amino acid transporter B0AT1, encoded by SLC6A19, are membrane proteins with pivotal roles in human physiology. ACE2 is involved in regulating blood pressure and serves as the cellular entry receptor for SARS-CoV-2, while B0AT1 facilitates amino acid absorption in the intestine. The interplay between ACE2 and B0AT1, particularly their physical interaction and co-expression in the intestine, underscores their relevance in both normal physiology and disease. Dysregulation of these proteins has been implicated in conditions such as hypertension, and Hartnup disease and they have been usurped by SARS-CoV-2 to cause COVID-19. Despite their …

The Epidemiology Of Major Congenital Anomalies In The United Arab Emirates: The Mutaba'ah Study, Hiba Mahdi Adam

Dissertations

Major Congenital Anomalies (MCAs) are significant contributors to perinatal morbidity and mortality. The absence of clear baseline prevalence data for MCAs hinders the development of targeted interventions to mitigate their burden. Furthermore, studies on adverse obstetric and birth outcomes in pregnancies complicated by MCAs are scarce, emphasizing the need for research to enhance management strategies. This dissertation aimed to: (1) estimate the live birth prevalence of perinatally diagnosed MCAs and describe study population characteristics by MCA status, (2) investigate the impact of MCAs on fetal presentation and delivery mode, and (3) investigate the impact of MCAs on preterm and low …

Strengthening The Paediatric Clinical Trial Ecosystem To Better Inform Policy And Programmes, James A. Berkley, Judd L. Walson, Glenda Gray, Fiona Russell, Zulfiqar Ahmed Bhutta, Per Ashorn, Shane A. Norris, Ebunoluwa A. Adejuyigbe, Rebecca Grais, Bernhards Ogutu

Institute for Global Health and Development

The first WHO Global Clinical Trials Forum was convened in November, 2023 to develop a shared vision of an effective global clinical trial infrastructure. The Paediatric Clinical Trials Working Group was formed to provide perspectives, identify challenges, and propose solutions to strengthen the paediatric clinical trials ecosystem. Participants represented paediatric disciplines, including infectious diseases, nutrition, neonatology, pharmacology, oncology, neurodevelopment, public health, and policy. Childhood diseases have profound lifelong effects on health, livelihoods, and societies. Investment in early childhood results in highly cost-effective changes to lifelong health, productivity, and human capital returns. Yet, there remain substantial gaps in knowledge on the …

Interspecific Sources Of Resistance For Neisseria Gonorrhoeae: Investigating Horizontally Transferred Antimicrobial Resistance Markers, Makenna Swartz

Theses

Antibiotic resistance is a growing public health crisis, limiting treatment options and increasing the burden of infectious diseases. Bacteria can rapidly gain resistance through mutations and horizontal gene transfer (HGT). Understanding these mechanisms is critical for developing strategies to mitigate resistance and preserve antibiotic efficiency. Neisseria gonorrhoeae, the causative agent of gonorrhea, has developed resistance to multiple antibiotics, and has only one remaining treatment option. Commensal species are constantly exposed to antibiotics in humans, and over time acquire resistant mutations that then transfer to pathogenic species through HGT. Investigating these exchanges can provide insight into how resistance evolves and spreads …

Insights Into Covid-19 Dynamics Via The Integration Of Subpopulations, Vaccinations, And Bayesian Calibration In A Semi-Enclosed Community Model Framework, Meghan Rowan Childs

Theses

From the beginning of the COVID-19 pandemic, universities have experienced unique challenges due to their multifaceted nature as a place of education, residence, and employment. Previous work has used mathematical models to explore varying approaches to combating COVID-19 and tailored these models to local contexts, such as hospitals. However, previous work has not broadly incorporated pharmaceutical mitigation strategies into university models. We address this gap in research by integrating subpopulations, vaccines, and COVID-19 variants into a semi-enclosed population model framework. We further improve the quantification of uncertainty in the model parameters by implementing a formal Bayesian model calibration, fusing real-world …

Spring 2025, Humayun Islam

PMI Newsletter

No abstract provided.

Glucose Uptake In Pigment Glia Suppresses Tau-Induced Inflammation And Photoreceptor Degeneration, Mikiko Oka, Sho Nakajima, Emiko Suzuki, Shinya Yamamoto, Kanae Ando

Duncan NRI Faculty and Staff Publications

Brain inflammation contributes to the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease (AD). Glucose hypometabolism and glial activation are pathological features seen in AD brains; however, the connection between the two is not fully understood. Using a Drosophila model of AD, we identified that glucose metabolism in glia plays a critical role in neuroinflammation under disease conditions. Expression of human MATP (hereafter referred to as Tau) in the retinal cells, including photoreceptor neurons and pigment glia, causes photoreceptor degeneration accompanied by the formation of dark-stained round inclusion-like structures and swelling of the lamina cortex. We found that inclusion-like structures …