Digital Commons Network^™

Delivering Infectious Disease Interventions To Women And Children In Conflict Settings: A Systematic Review, Sarah Meteke, Marianne Stefopulos, Daina Als, Michelle Gaffey, Mahdis Kamali, Fahad J. Siddiqui, Mariella Munyuzangabo, Reena P. Jain, Shailja Shah, Amruta Radhakrishnan, Anushka Ataullahjan, Zulfiqar Ahmed Bhutta

Woman and Child Health

Background: Conflict has played a role in the large-scale deterioration of health systems in low-income and middle-income countries (LMICs) and increased risk of infections and outbreaks. This systematic review aimed to synthesise the literature on mechanisms of delivery for a range of infectious disease-related interventions provided to conflict-affected women, children and adolescents.
Methods: We searched Medline, Embase, CINAHL and PsychINFO databases for literature published in English from January 1990 to March 2018. Eligible publications reported on conflict-affected neonates, children, adolescents or women in LMICs who received an infectious disease intervention. We extracted and synthesised information on delivery characteristics, including delivery …

'The Miracle Mothers And Marvelous Babies': Psychosocial Aspects Of Surrogacy - A Narrative Review, Ansha Patel, Pratap Kumar, P. S.V.N. Sharma

Open Access archive

Surrogates are described in literature as true angels 'who make dreams happen.' On the other hand, surrogacy has also been surrounded by several psychosocial controversies. In this review, we have made an attempt to encapsulate this topic from the multiple perspectives of individuals who are involved in the surrogacy cycle. We present to the readers the various outlooks and dilemmas of the clinicians, patient parties contracting for surrogacy, the child born out of surrogacy, and the intricate role of the mental health professionals in surrogacy arrangements. The review also throws light upon the psychosocial issues in connection to the evolving …

Vaccinate Her? I Hardly Know Her!: Understanding Vaccine Hesitancy, Zachary M. Marcum

Honors Theses

Vaccines are a first defense against highly communicable diseases such as measles. For vaccines to protect the population, a vast majority must be vaccinated to maintain herd immunity. Vaccine hesitancy is delaying vaccination from the suggested schedule or refusing vaccination outright. The hesitance is commonly portrayed as a lack of knowledge or scientific literacy. But highly educated people are still just as likely to be hesitant. The basis of hesitance is likely ethically similar to that of vaccination. Understanding the methods of the vaccine hesitant will better inform attempts to persuade them. Individuals have an obligation to the community to …

Systematic Review Of Integrating Care To Improve Quality Of Life Within Chronically Diseased Patients With Mental Illness, Brooke R. Goble

Honors Theses

Chronic disease and mental illness affects a multitude of individuals in the United States. Sufficient treatments exist for chronic diseases and mental illnesses, separately. However, a gap in care exists in individuals who have co-occurring conditions. The presence of one or more chronic conditions, or comorbidities, has been observed by several providers, yet there is a crucial need for integrated care in the case of chronically diseased individuals with mental illness. Increasing quality of life within this vulnerable population is a necessity. The purpose of this systematic review is to determine whether integrated care and collaboration between behavioral health and …

Substance Abuse: The Impact Of Maternal Drug Use On Families, Anne Kinsman

Honors Theses

This research study was conducted through interviews at Liberty Place in Richmond, Kentucky, a rehabilitation center for women. The women who volunteered to participate in this study at Liberty Place had to have at least one child. The six participants were asked eight questions regarding their experiences as a mother at Liberty Place. They were also invited to do a painting activity to create a canvas to honor mothers like them seeking treatment at Liberty Place. This honors thesis highlights issues that arise when a mother is abusing substances. There are countless problems that family members may face when someone …

Optimal Control Of An Epidemic Through Social Distancing, Thomas Kruse, Philipp Strack

Cowles Foundation Discussion Papers

We analyze how to optimally engage in social distancing in order to minimize the spread of an infectious disease. We identify conditions under which any optimal policy is single-peaked, i.e., first engages in increasingly more social distancing and subsequently decreases its intensity. We show that an optimal policy might delay measures that decrease the transmission rate substantially to create herd-immunity and that engaging in social distancing sub-optimally early can increase the number of fatalities. Finally, we find that optimal social distancing can be an effective measure and can substantially reduce the death rate of a disease.

Comparison Of Multi-Parallel Qpcr And Double-Slide Kato-Katz For Detection Of Soil-Transmitted Helminth Infection Among Children In Rural Bangladesh, Jade Benjamin-Chung, Nils Pilotte, Ayse Ercumen, Jessica R. Grant, Jacqueline R.M.A. Maasch, Andrew M. Gonzalez, Ashanta C. Ester, Benjamin F. Arnold, Mahbubur Rahman, Rashidul Haque, Alan E. Hubbard, Stephen P. Luby, Steven A. Williams, John M. Colford

Biological Sciences: Faculty Publications

There is growing interest in local elimination of soil-transmitted helminth (STH) infection in endemic settings. In such settings, highly sensitive diagnostics are needed to detect STH infection. We compared double-slide Kato-Katz, the most commonly used copromicroscopic detection method, to multi-parallel quantitative polymerase chain reaction (qPCR) in 2,799 stool samples from children aged 2–12 years in a setting in rural Bangladesh with predominantly low STH infection intensity. We estimated the sensitivity and specificity of each diagnostic using Bayesian latent class analysis. Compared to double-slide Kato-Katz, STH prevalence using qPCR was almost 3-fold higher for hookworm species and nearly 2-fold higher for …

The Impact Of Dental Caries On Oral Health Related Quality Of Life Amongst Adult Population In Lahore, Pakistan, Hazik Bin Shahzad, Faiza Awais, Um-E-Rubab Shirazi, Hanna Abdul Majeed, Aqeela Rafique, Maliha Shahbaz

Makara Journal of Health Research

Background: Dental caries in adults is a public health problem. A comprehensive assessment of the association between caries and Oral Health Related Quality of Life (OHRQoL) measures is essential for understanding how it impacts the daily life of people and for assessing their oral health needs.

Methods: The survey was conducted at Rashid Latif Dental Hospital, from March-June 2019. A total of 373 adults aged 18-80 years were randomly enrolled in the study. Dental caries was the main exposure, measured clinically. The OHRQoL was measured through Oral Impacts on Daily performance (OIDP) questionnaire. Caries was dichotomized and the relationship to …

A Bioinformatics Study: Differential Analysis Of Hsv-1 And The Live-Attenuated Vaccine Vc2 To Determine Biological Implications In Enhanced Protection Against Lethal Hsv-1 Infection, Hebah Shaikh

Honors Capstones

No abstract provided.

Review Of Racial Disparities: Healthcare, Health Outcomes, And Outreach Programs, Lauren Bagneris

Honors Capstones

No abstract provided.

Joint International Consensus Statement For Ending Stigma Of Obesity, Francesco Rubino, Rebecca M. Puhl, David E. Cummings, Robert H. Eckel, Donna H. Ryan, Jeffrey I. Mechanick, Joe Nadglowski, Ximena Ramos Salas, Phillip R. Schauer, Douglas Twenefour, Caroline M. Apovian, Louis J. Aronne, Rachel L. Batterham, Hans Rudolph Berthoud, Camilo Boza, Luca Busetto, Dror Dicker, Mary De Groot, Daniel Eisenberg, Stuart W. Flint, Terry T. Huang, Lee M. Kaplan, John P. Kirwan, Judith Korner, Ted K. Kyle, Blandine Laferrère, Carel W. Le Roux, La Shawn Mciver, Geltrude Mingrone, Patricia Nece, Tirissa J. Reid, Ann M. Rogers, Michael Rosenbaum, Randy J. Seeley

Division of Basic Science Faculty Publications

People with obesity commonly face a pervasive, resilient form of social stigma. They are often subject to discrimination in the workplace as well as in educational and healthcare settings. Research indicates that weight stigma can cause physical and psychological harm, and that affected individuals are less likely to receive adequate care. For these reasons, weight stigma damages health, undermines human and social rights, and is unacceptable in modern societies. To inform healthcare professionals, policymakers, and the public about this issue, a multidisciplinary group of international experts, including representatives of scientific organizations, reviewed available evidence on the causes and harms of …

Inspire : Vol 3, Issue 4, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Message From the Chair
• COVID-19: Crisis Inspiring Virtual Innovations
• Nephrology and Urology Simulation-based Workshops
• Featured Faculty: Dr Saad Shafqat
• “Take exemplary care of your patients. If you do that with honesty and ability, all good things will follow”
• Publications

Development And Diagnostic Application Of Monoclonal Antibodies Against Swine Acute Diarrhea Syndrome Coronavirus (Sads-Cov), Molly Kroeger

Schultz-Werth Award Papers

Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV) is a member of the Coronaviridae family. The virus is associated with severe small intestine inflammation and diarrhea in suckling piglets. In 2017, SADS-CoV was first detected and identified as the causative agent of a devasting swine disease outbreak in southern China. Routine monitoring and early detection of the source of infection is therefore integral to the prevention and control of a SADS-CoV outbreak in the United States. However, the United States does not currently have any diagnostic or surveillance tests to identify this emerging disease. To address these industry needs, we developed monoclonal …

Pre-Exposure Prophylaxis For Preventing Acquisition Of Hiv: A Cross-Sectional Study Of Patients, Prescribers, Uptake, And Spending In The United States, 2015-2016, Stephanie S. Chan, Andre R. Chappel, Karen E. Joynt Maddox, Karen W. Hoover, Ya-Lin A. Huang, Weiming Zhu, Stacy M. Cohen, Pamela W. Klein, Nancy De Lew

Open Access Publications

BACKGROUND: In 2015, there were approximately 40,000 new HIV diagnoses in the United States. Pre-exposure prophylaxis (PrEP) is an effective strategy that reduces the risk of HIV acquisition; however, uptake among those who can benefit from it has lagged. In this study, we 1) compared the characteristics of patients who were prescribed PrEP with individuals newly diagnosed with HIV infection, 2) identified the specialties of practitioners prescribing PrEP, 3) identified metropolitan statistical areas (MSAs) within the US where there is relatively low uptake of PrEP, and 4) reported median amounts paid by patients and third-party payors for PrEP.

METHODS AND …

The Domestic And Global Implications Of Considering Non-Us Origin A Risk Factor For Tuberculosis In The United States, Emma Gile 20

Honor Scholar Theses

No abstract provided.

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To evaluate whether children who are malnourished/stunted are more likely to have experienced infectious disease.

METHODS: 6th and 7th students (n=546) were interviewed about health history and assessed using anthropometry.

RESULTS: Children who are short for their age also have higher rates of stunting. Malaria is the most experienced infectious disease.

CONCLUSIONS: Given that malaria was the most common infectious disease experience listed among middle school children, and that those who have experienced disease are more likely to be stunted, increased malaria prevention methods may improve the long-term health of Ethiopian and Zambian schoolchildren.

Occurrence And Persistence Of Antibiotics Administered To Cattle In A Newly Established Feedlot, Brittany Trejo

Department of Environmental Engineering: Theses and Other Student Research

The common practice of using therapeutic antibiotics in livestock farming is a worldwide phenomenon. Over the last decade, there has been a growing concern of antibiotics entering the environment via animal manure. Similar studies have focused on the occurrence and biological effects of antibiotics in land-applied animal feedlots; however, limited research has been conducted on the occurrence and persistence of antibiotics in animal feedlots. A study was conducted to investigate the occurrence and persistence of four injected antibiotics (ceftiofur enrofloxacin, florfenicol, and tulathromycin) and two continuously fed antibiotics (monensin and tylosin) in feedlot sediment, runoff, and sediment runoff. For antibiotics …

The Effects Of Racialization On Skeletal Manifestations Of Disease Among Migrants In Historic St. Louis, Missouri, Kristina M. Zarenko

Theses and Dissertations

This research investigates the biological effects of racialization on migrants in late nineteenth and early twentieth century St. Louis, Missouri. Racialization is a form of structural violence in which real or perceived physical differences contribute to the creation of hierarchical racial categories along a continuum of whiteness. German and Irish immigrants and African American migrants from the South came to St. Louis in search of economic prosperity and in an attempt to escape poverty, famine, or conflict in their places of origin. However, racialization affected each migrant group’s access to housing and employment as well as their exposure to violence. …

2020 Imsaloquium, Illinois Mathematics And Science Academy

IMSAloquium Event Booklets

Welcome to IMSAloquium 2020. This is IMSA’s 33rd year of leading in educational innovation, and the 32nd year of the IMSA Student Inquiry and Research (SIR) Program.

Developing Agent-Based Models To Study Financial Markets, Saurav Chakraborty

USF Tampa Graduate Theses and Dissertations

This dissertation presents research that employs agent-based modelling to provide a framework to support simulation as a complement to traditional economic models for policy evaluation. It consists of three studies. The first study employs cluster analysis to capture the different types of banks and the associated business models that define their decision-making. The results from study one will help us get an understanding of how different banks behave and provide an insight into their lending practices. Hence, it would be very helpful in evaluating and analyzing the impact of future policies. Study two develops a fine-grained interbank lending model based …

A Survey Of Patients With Congenital Orthopedic Conditions In Malawi: Factors That Influence Late Presentation, Brianna Wallis

Undergraduate Honors Thesis Projects

Staff at CURE International, a non-profit organization that provides orthopedic care in Malawi, noticed a high prevalence of patients with congenital orthopedic conditions who are presenting late for treatment. Late presentation results in prolonged pain or discomfort for the patient and has the potential for increased cost to the institution, longer duration of treatment, and decreased quality of outcomes. To identify the factors that influenced presentation delays, we surveyed the caregivers of patients with congenital conditions that were seen in out-patient clinics, in-patient wards, and mobile clinics across the country. Sixty-two caregivers were surveyed; forty-two patients had a diagnosis of …

The Applicability Of Occupational Therapy To Correctional Programming, Jordan Lanning

Honors Projects

Correctional facilities are a controversial topic in the United States. Whether it is prison reform policy or overcrowding issues that are being debated in a political setting or at the dinner table, it is a hot topic of conversation. The discussion goes around and around to no avail, and seemingly no one is satisfied. A detailed look at current issues facing corrections, what has been done, and then, potentially what could be done may provide some clarity for a situation that is seemingly spinning out of control. Furthermore, occupational therapy and its application to correctional programming is explored as a …

Eliminating Mandatory Minimum Sentences: Putting Sentencing Power Back In The Hands Of The Judiciary, Hunter Anderson, Joseph Dummar

Brigham Young University Prelaw Review

Ron Miller had been a general manager of a company for twentyfour

years with no criminal record when his best friend asked

him to allow a shipment of drugs to be delivered to his company’s

address. Ron reluctantly agreed to help his friend, who was desperate

for money. Before the drugs arrived, Ron backed out and asked

his friend not to send the drugs, but by that point the shipment had

already been made. The police tracked the shipment to Ron and

arrested him. Even though Ron never knew the type nor the quantity

of drug that was delivered to …

Anthrax Event Detection Using Twitter: Analysis Of Unigram And Bigrams For Relevant Vs Non-Relevant Tweets, Michele Miller, William L. Romine

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Due to the lack of anthrax attacks in recent times, researchers have used naturally occurring events to assess their anthrax detection models, but these provide little information on how the models will perform in the context of an unannounced, intentional release of a bioterrorism agent, like anthrax. Therefore, it is important to develop a detection model using data surrounding real anthrax scares and events.We develop a methodology to detect an anthrax-related event on Twitter. We describe a process to separate the tweets concerning anthrax-related events from those not related so experts can address misconceptions and fears in real-time.Most tweets were …

Enhanced Expression Of Receptor Tyrosine Kinase Mer (Mertk) On Socs3-Treated Polarized Raw 264.7 Anti-Inflammatory M2c Macrophages, Sankhadip Bhadra

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Macrophages are phagocytic cells located in tissues, organs and even circulated within our body as white blood cells. Based on the local cytokine milieu in tissue sites, macrophages may be polarized into pro-inflammatory M1 or anti-inflammatory M2 phenotypes. Receptor tyrosine kinase Mer (MERTK) helps in clearing dead neutrophils and other apoptotic cells from damaged tissue sites preventing chronic inflammation and autoimmune disorders. MERTK aids in the maintenance of tissue homeostasis and wound healing. Phosphatidylserine (PtdSer) present on the surface of apoptotic cells release “eat me” signals which are recognized by the two “bridging ligands” of MERTK receptor, Gas6 and ProS. …

The Contemporary Porn Debate - Perceptions Of Sexual Health Of Porn Actors, The 2013 Hiv Crisis, And Recognizing The Complexities Of The Porn Industry, Nasreen C. Gooya

Student Publications

Between August 2012 and January 2013, four adult film performers based in California tested positive for HIV which triggered a moratorium on production, and led the state of California to mandate condom usage in the industry under the Safer Sex in the Adult Industry Act – otherwise referred to as Measure B. The goal of this research is to explore how the discourse surrounding health in the adult film industry, specifically sexual health in relation to the adult film performers during this event, is reflective of contemporary anti-pornography sentiments. These sentiments and biases ultimately lead to regulations of the industry …

Environmental Injustice's Impact On Asthma Disparities In Nyc, Tayler J. Rodriquez

Student Publications

Understanding the social determinants of health is essential when looking at low-income minorities in urban cities. Social determinants of health are conditions in the environment in which people are born, which affects a wide range of health and quality-of-life outcomes. Amongst other determinants, adequate housing can have a significant influence on population health outcomes such as asthma. Zoning inequality negatively and disproportionately impacts the health and the overall quality of life of low-income minorities; zoning is correlated to environmental injustice fueling adverse health effects and health disparities among low-income minority populations. Without the opportunity to receive adequate and affordable housing, …

Increasing Adult Influenza Vaccination Rates In The Primary Care Setting, Leah Prescott Msn, Fnp-Bc

Doctor of Nursing Practice Projects

Background: Provision of vaccinations is one of the most basic interventions aimed at health promotion and disease prevention in the primary care setting. Despite increased public awareness and improved access to vaccinations through minute-clinic settings, health fairs, and employer-offered vaccination clinics, adults in the United States continue to fall short of national goals. Literature demonstrates vaccination rates among adults vary widely and may be affected by a multitude of factors, however vaccination rates may be greatly improved with increased provider engagement.

Objectives: The purpose of this project was to develop, implement, and evaluate a program to improve immunization rates in …

How Can Pennsylvania Protect Itself From Its Own Measles Outbreak?, Megan M. Riesmeyer, Kristen Feemster

Faculty Scholarly Works

When a response to inaccurate information strives to be an informative exercise of its own, it is difficult to balance the desire to respond point by point to mischaracterized, misleading, or untrue information, with the need to simply offer a complete picture of facts. This article is a response to Abigail Wenger’s article regarding

vaccinations. To reply to each mischaracterization or inaccuracy in turn means this response loses its own informative intent and becomes simply a rebuttal. However, to ignore mischaracterizations and inaccuracies is to risk the reader’s acceptance of those points as true. Through illustrative examples in the United …

2020-April-01-Etsu Health To Transition Drive-Through Covid-19 Testing Site To Health Department, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (April 1, 2020) – With an increase in regional COVID-19 testing capacity, ETSU Health will close its drive-through COVID-19 testing site, located at 325 North State of Franklin, effective April 1, 2020. While the drive-through site will no longer be open, ETSU Health will continue to administer COVID-19 testing in its clinics.

“The local health department has just opened their drive-through testing sites in Washington County and the surrounding counties,” said Dr. Jonathan Moorman, chief of the Division of Infectious Diseases at East Tennessee State University’s Quillen College of Medicine. “These new sites are open to the public …