Digital Commons Network^™

Expression And Roles Of Antimicrobial Peptides In Innate Defense Of Airway Mucosa: Potential Implication In Cystic Fibrosis, Regina Geitani, Carole Ayoub Moubareck, Zhengzhong Xu, Dolla Karam Sarkis, Lhousseine Touqui

All Works

© Copyright © 2020 Geitani, Moubareck, Xu, Karam Sarkis and Touqui. The treatment of respiratory infections is associated with the dissemination of antibiotic resistance in the community and clinical settings. Development of new antibiotics is notoriously costly and slow; therefore, alternative strategies are needed. Antimicrobial peptides (AMPs), the central effector molecules of the immune system, are being considered as alternatives to conventional antibiotics. Most AMPs are epithelium-derived and play a key role in host defense at mucosal surfaces. They are classified on the basis of their structure and amino acid motifs. These peptides display a range of activities, including not …

Review Article: Presepsin: New Biomaker To Evaluate Empirical Antibiotic Therapy Outcome In Septic Condition, Aldita Cahyani Puspitasari, Ayu Mawari

Folia Medica Indonesiana

This review presents key publications from the research field of new biomarker of sepsis and other relevant journals during 2009-2015. The results of these experimental studies and clinical trials are discussed in the context of biomarker for sepsis and the accuracy of presepsin for optimising antibiotic therapy. The discussion highlights and summarises articles on three main topics: diagnostic and prognostic biomarkers, presepsin as new biomarkers, and outcome studies. According to the review, presepsin is specific biomarker for bacterial infections compare with CRP and PCT. It may be useful to evaluate the empirical antibiotic outcome in sepsis condition.

Asymmetric Effect Of Crude Oil And Palm Oil Prices On Economic Growth: Evidence From Indonesia, Kp Prabheesh, Nisful Laila

Bulletin of Monetary Economics and Banking

This paper empirically examines the impact of the price of crude oil petrol and palm oil on Indonesia's economic growth. Using quarterly data from 2000 to 2019 and linear, and non-linear autoregressive distributed lag (ARDL) model to cointegration, the study finds 1) A significant non-linear effect of oil prices on country's output. 2) The palm oil price changes have a higher effect on the country's output as compared to petroleum prices. 3) A decline in palm price in the international market leads to a higher adverse effect on the country's economic growth as compared to petroleum prices.

External Debt, Institutional Quality And Economic Growth, Siti Nurazira Mohd Daud

Bulletin of Monetary Economics and Banking

This paper addresses the gap in the literature by investigating the role of the institutional quality in the nexus of external debt and economic growth. By employing a dynamic panel data analysis, we found that the institutional quality plays some role in complementing the effect of external debt on a country’s economic growth. We also found that the negative effect of external debt and a country’s economic growth monotonically increases with the level of institutional indicator, which implies the possibility of debt overhang may still happen in economies endowed with good institutions, but for higher values of debt.

The Role Of Palm Oil Price In Indonesia’S Aggregate Demand, Susan Sunila Sharma

Bulletin of Monetary Economics and Banking

This study examines the predictability of Indonesia’s aggregate demand using palm oil price. We conduct both in-sample and out-of-sample forecasting evaluations. These evaluations are based on time-series quarterly and monthly data frequencies and cover three different forecasting horizons. Overall, we find that palm oil price predicts real GDP, consumption expenditure, total investment, net spending from overseas, while predictability of government spending is sensitive to the use of forecasting approaches and horizons.

Financial Stability And Income Growth In Emerging Markets, Bashir T. Mande, Afees A. Salisu, Adeola N. Jimoh, Fola Dosumu, Girei H. Adamu

Bulletin of Monetary Economics and Banking

In this paper, we examine the extent to which financial stability matters for income growth in emerging markets. Using dynamic panel estimation techniques, we explore both the stock market and banking sector dimensions of the financial system to show that both stock market volatility and non-performing loans are detrimental to income growth in these markets. We, however, find the magnitude of the impact to be relatively more pronounced when the underlying source of instability in the financial system is stock market volatility. Overall, we find the impact of financial stability on income growth to be more statistically relevant when measured …

Comparison Between Exposure Of Ciprofloxacin And Cefotaxime On Developing Of Escherichia Coli Esbl, Muhammad Amin, Eddy Bagus Wasito, Erwin Astha Triyono

Folia Medica Indonesiana

This study aimed to compare ciprofloxacin and cefotaxime exposure to develop ESBL producing Escherichia coli (E. coli). A total of 16 isolates of cefotaxime sensitive E. coli and ciprofloxacin were exposed to ciprofloxacin and cefotaxime for 14 days using the Kirby-Bauer antibiotic disc diffusion method. Colonies that grew on the edge of the inhibiting zone were exposed each day by the same method. Furthermore, we observed the occurrence of resistance to cefotaxime as ESBL screening test. Isolates were resistant, the following day the ESBL was confirmed by the Modified Double Disk Sinergy Test (MDDST) method using Cefotaxime (CTX), Ceftazidime (CAZ), …

The Pattern Of Antibiotic Prescription And Antimicrobial Resistance Of Gut Flora Escherichia Coli At Aisyiyah Hospital, Bojonegoro, Ana Nurlaili Hidayah, Didik Hasmono, Muqoddar Thayyib, K Kuntaman

Folia Medica Indonesiana

Antimicrobial resistance (AMR) is the failure of antibiotic to kill bacteria and becomes ineffective in therapeutic purpose. The AMR bacteria is a major health problem worldwide and Indonesia is not exception. AMR is increased by two factors, higher antibiotic use and low compliance in infection control and prevention. WHO has recommended 7 bacterial indicators as point of view in surveillance, one of these bacteria is Escherichia coli. This study aimed to analyze the correlation between antibiotic use and resistance pattern of gut flora Escherichia coli. The study was conducted at Aisyiyah Hospital, Bojonegoro from June to October 2017. Total 101 …

Effect Of Glucose Induction On Biofilm Density In Clinical Isolate Acinetobacter Baumannii Patients In Intensive Care Unit Of Dr. Soetomo Hospital, Surabaya, Wira W Lindarto, Eddy Bagus Wasito, Kartuti Debora

Folia Medica Indonesiana

This study aimed to analyze the effect of glucose induction on the clinical isolate biofilm density of Acinetobacter baumannii. Thirteen clinical isolates of A. baumannii non biofilm forming were collected from non-DM patients who were treated at the ICU of Dr. Soetomo Hospital, Surabaya, was treated with the addition of 0.08% glucose, 0.15% glucose, 0.2% glucose, and 0.4% glucose in TSB growth media, followed by biofilm density examination with Tissue Culture Plate Method (TCPM) using 96 wells flatbottomed polyesterene tissue culture plate and read by autoreader ELISA with a wavelength of 630 nm (OD630). Biofilm density obtained was analyzed using …

Estimation Of Immunoglobulin A, Immunoglobulin G, And Immunoglobulin M Antibody Levels In Laboratory Mice Balb/C Infected With Entamoeba Histolytica And Treatment With Aqueous Extracts Of Cyperus Rotundus And Thymus Serpyllum, Farhan K. Hussein, Ashraf J. Mahmoud, Buthainah J. Yousif

Polytechnic Journal

Sixty Balb/c mice (Mus musculus) were used in the present study. It was conducted out in the animal house of the Department of Biology/College of Education for Women. The mice were infected with Entamoeba histolytica isolated from positive stool samples obtained from children in pediatric hospital in Kirkuk city governorate followed by treatment with aqueous extract of Cyperus rotundus and Thymus serpyllum. Results revealed a significant increase of P < 0.05 in immunoglobulin A, immunoglobulin G,, and immunoglobulin M antibody levels among infected mice when it was compared with the control and treated groups of aqueous extracts of studied plant. This indicates the efficacy of these extracts as treatment.

The Impact Of Probiotics In Respiratory Diseases, Rafee H. Askandar, Nasim Ebrahimi

Polytechnic Journal

Probiotics are viable microorganisms that, if adequately administered, confer great benefits to the host for the prevention or treatment of a wide range of human diseases, including recurrent respiratory tract infection (RRTI), cystic fibrosis, allergies, and chronic obstructive pulmonary disease (COPD). One of the current problems is that the overuse of antibiotics during respiratory tract infection has led to increased resistance to them, which has been demonstrated in numerous examinations that specific lactic acid bacteria (LAB), one of the key probiotics, against bacterial and viral infections of the respiratory and gastrointestinal tract, have a protective effect. On the other hand, …

Identifying Epidemic Candidates Using Mobile Devices, N/A

Defensive Publications Series

This publication describes systems and techniques for identifying epidemic candidates utilizing mobile device location information. Through the use of beacons and cryptographic data, the privacy and location of a user of the mobile device are protected. The mobile device generates a beacon that includes cryptographic data, broadcasts the beacon via wireless communication from the mobile device, monitors for beacons communicated wirelessly, receives beacons from other mobile devices, stores beacons from other mobile devices for a configurable time period, communicates with a server to receive a beacon broadcast, calculates an identification using a timestamp included in the beacon broadcast, compares the …

Ics - Intelligent Crisis Communication - Method And Control Device For Human-Machine-Environment Data Collection And Data Exchange With An Authority, Verena Blunder

Defensive Publications Series

No abstract provided.

2020-06-29_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Gw Covid-19 Intelligence Reports: June 29, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Governor Ivey Announces Covid-19 Testing, Safety Programs Developed By Uab And The State Department Of Public Health To Support Higher Ed Statewide, Tyler Greer

Browse All News

No abstract provided.

Nurses Drawdown: A New Nursing Community For Climate Solutions, Katie Huffling, Cara Cook

Climate Change Webinars (Sigma and ANHE)

Join us for an inspiring webinar describing the newly launched Nurses Drawdown. Nurses have always known that the best way to prevent needless suffering and disease is through strong and effective public and population health. As recent events have shown, to help prevent future pandemics we need a healthy planet that supports healthy people. Nurses Drawdown is an evidenced based tool for nurses to engage in climate solutions and is a community of nurses from around the world who are working together to make our planet one that supports a healthier future for all.

Learning Objectives:

1. Describe the Nurses Drawdown …

2020-2021 Faculty Senate Xxv - June 29, 2020 Minutes Summary, Faculty Senate

Faculty Senate Agendas & Minutes

No abstract provided.

Rapid Vertical Flow Assay On Aunp Plasmonic Paper For Sers-Based Point Of Need Diagnostics, Richard Frimpong

Theses and Dissertations

SERS based immunoassays for point-of-care diagnostics is a promising tool to facilitate biomarker detection for early disease diagnosis and control. The technique is based on a sandwiched system in which antigen is first captured by a selective substrate and then labeled by an extrinsic Raman label (ERL). Here, we report on the use of gold nanoparticle modified filter paper as a novel capture membrane in a vertical flow format. This vertical flow configuration affords reproducible flow of sample and label through the capture substrate to overcome diffusion limited kinetics and significantly reduced assay time. The filter paper was selected due …

Developing Alternatives To Protect Domestic Sheep From Predation In South Africa, David L. Bergman, Nico L. Avenant, Michael J. Bodenchuk, Eddie Steenkamp

United States Department of Agriculture Wildlife Services: Staff Publications

South Africa has approximately 8,000 commercial small livestock farms and 5,800 communal/subsistence farmers throughout the country. Reported rates of small livestock loss to predation range from 3-13% and 0.5-19% from communal farming areas. A range of predators exist on the African continent, but in southern Africa major livestock losses are primarily due to black-backed jackal and caracal. South Africans have been managing caracals and jackals for over 300 years with no elimination of predation. During the aforementioned time frame, producers have used and/or developed a number of techniques including lethal, nonlethal, and integrated predator damage management to address predation losses. …

No More “Social Distancing” But Practice Physical Separation, Debasree Das Gupta, David W. S. Wong

Kinesiology and Health Science Faculty Publications

Though not a new term, “social distancing” exploded onto the global stage as an expression to publicize the only means currently available to control the transmission of COVID-19. This term is increasingly being adopted and translated into the vernacular to inform and guide public behavior in most, if not all, countries around the world. However, any effective global response requires direct and unambiguous communication and sharing of ideas across communities with different cultural backgrounds as well as between researchers and responders across the disciplinary spectrum. Unfortunately, social distancing is a misnomer. The current use of social distancing – separating ourselves …

Prevalence, Incidence, And Clearance Of Human Papillomavirus Types Covered By Current Vaccines In Men With Human Immunodeficiency Virus In The Sun Study, Pragna Patel, Tim Bush, Lois Conley, Elizabeth R Unger, Teresa M Darragh, Keith Henry, Gerome Escota, John T Brooks, Erna Milunka Kojic

2020-Current year OA Pubs

BACKGROUND: High-risk anal human papillomavirus (HPV) infection is prevalent among men living with human immunodeficiency virus (HIV); the association between 9-valent (9v) high-risk HPV (HR-HPV) vaccine types and abnormal cytology has not been well characterized.

METHODS: We followed a prospective cohort study of persons with HIV at 7 HIV clinics in 4 US cities from March 2004 through June 2012. Annually, providers collected separate anal swabs for HPV detection and cytopathologic examination. Among men, we examined prevalence, incidence, and clearance of 9v HR-HPV vaccine types, compared with other HR types, and associations with abnormal cytology to assess potential vaccine impact. …

Medical School Watercooler Newsletter - June 28, 2020, Lindsey Lyle

Watercooler Newsletter

This is the June 28, 2020 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

What’s ‘universal masking’ at USA Health?

Conference on Mental Health set for July 29

2020-06-28_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Research Progress In Food-Derived Functional Peptides, Wang Shao-Yun, Yang Qian, Cai Xi-Xi, Chen Xuan, Chen Xu, Yang Fu-Jia, Wu Xiao-Ping

Food and Machinery

This review summarized the species, preparation methods and biological activities of food-derived functional peptides, and predicted the future research direction and good application prospects of food-derived functional peptides.

Phenotypic Profiling In Subjects Heterozygous For 1 Of 2 Rare Variants In The Hypophosphatasia Gene (Alpl), Daniel R Tilden, Jonathan H Sheehan, John H Newman, Jens Meiler, John A Capra, Andrea Ramirez, Jill Simmons, Kathryn Dahir

Open Access Publications

CONTEXT: Hypophosphatasia (HPP) is a syndrome marked by low serum alkaline phosphatase (AlkP) activity as well as musculoskeletal and/or dental disease. While the majority of subjects with HPP carry a pathogenic variant in the

METHODS: Through BioVU, a DNA biobank that pairs individuals' genetic information with their de-identified medical records, we identified subjects with 2 rare variants with distinct reported clinical phenotypes (p.D294A and p.T273M). We then performed a manual review of these subjects' de-identified medical records along with computational modeling of protein structure to construct a genetic, biochemical and clinical phenotype for each subject and variant.

RESULTS: Twenty subjects …

Adsorption Behavior Of Chemically / Charged Modified Antibodies On Gold Nanoparticles, Samuel Okyem

Theses and Dissertations

Gold nanoparticles (AuNPs) have been exploited in the various domains of science such as drug delivery, bio-sensing, immunoassays and environmental sensors, due to their optical properties and intriguing surface chemistry. Different scientific procedures have been used to effectively immobilize antibodies onto AuNPs. Although acceptable outcomes have been achieved in the immobilization of antibodies onto AuNPs, the sensitivity of these immobilized antibodies to target antigen or binding sites is limited due to improper orientation of the antibodies. Also, the possibility of nanoparticle aggregation when exposed to proteins limits its biomedical applicability.

There is some evidence that the surface charge of antibodies …

The Future Importance Of Travel Health In The Middle East: Oman’S Opportunity To Enhance Its Services, Seif Al-Abri, Said Al-Lamki, Eskild Petersen, Ahmed Al-Mandhari

Sultan Qaboos University Medical Journal

No abstract provided.

Antimicrobial Strategies For Topical Applications, Kelsey Marie Lopez

LSU Doctoral Dissertations

Bacteria can thrive in diverse environments and are often harmless or beneficial. Bacteria in digestive tracts is one example of beneficial bacteria; however, bacteria can be harmful and when this type proliferates, it can cause infections within hosts. Bacterial infections are easily treated with antibiotics in most cases. However, bacteria are also capable of developing mutations which could cause them to become multi-drug resistant and eventually, “superbugs.” Therefore, the development of novel antimicrobial agents and materials capable of combating drug-resistant bacteria is necessary. Research presented in this dissertation focuses on different strategies for minimizing and preventing topical bacterial infections using …

2020-06-27_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …