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Exploring The Mental Health Needs Of Intensive Care Unit Nurses Facing The Pandemic Of Covid-19, Bushra Salamah Sep 2020

Exploring The Mental Health Needs Of Intensive Care Unit Nurses Facing The Pandemic Of Covid-19, Bushra Salamah

The Eleanor Mann School of Nursing DNP Capstone Projects

Coronavirus disease (COVID-19) has spread domestically and internationally, with approximately 134 billion confirmed cases worldwide and over 2 million deaths attributed to the virus. Frontline healthcare workers are at a substantially higher risk of infection and death due to excessive COVID-19 exposure while also facing mental health challenges. Epidemiological data on the mental health statuses of frontline nurses is still limited. The aim of this study was to examine mental health (burnout, stress, emotional exhaustion, disengagement) and associated factors among Intensive Care Unit (ICU) Nurses who are caring for COVID-19 patients to support and maintain their psychological well-being.


Ua12/2/1 College Heights Herald, Vol. 96, No. 2, Wku Student Affairs Sep 2020

Ua12/2/1 College Heights Herald, Vol. 96, No. 2, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

  • Collins, Michael. Rough Start – COVID-19
  • Thornton, Maggie. What a WKU Student Learned from Her Experience with COVID-19
  • Harkreader, Dylan & Debra Murray. Programs That Rely On Hands-on Learning Adapt to Virtual Courses
  • Meyer-Thornton, Zane. Keep It Going
  • Hurst, Courtney, Robin Lester & Trenton Peyton. What Is Intercultural Student Engagement Center?
  • Sisler, Julie. WKU Grad Student: It’s On the Administration, Not the Students
  • Kieser, Nick. Football Takes Precautions to Kick Off Season COVID-Free
  • Warner, Casey: Setting Up – Football
  • Gaylord, Kaden. Making It Safe to …


Ppe Compliance And Knowledge Among Healthcare Staff, Beatrice Hagert, Nicole Krummel Sep 2020

Ppe Compliance And Knowledge Among Healthcare Staff, Beatrice Hagert, Nicole Krummel

Nursing DNP Projects

Abstract

Problem: One of the most important steps in infection prevention is the use of personal protective equipment (PPE) to protect patients and staff from infectious agents; yet, research indicates that PPE compliance remains suboptimal in many healthcare institutions.

Purpose: To identify the effect of a multidisciplinary education campaign on PPE compliance and knowledge among healthcare workers (HCWs) on a rehabilitation unit of a large, midwestern teaching hospital.

Methods: This project utilized pre-intervention observational audits and a survey to determine baseline PPE compliance and knowledge on the piloted units. A post-intervention survey was sent to HCW to assess for a …


Does Religiosity Affect Attitudes Toward The Ethics Of Tax Evasion? The Case Of Turkey, Robert W. Mcgee, Serkan Benk, Bahad?R Yüzba??, Tamer Budak Sep 2020

Does Religiosity Affect Attitudes Toward The Ethics Of Tax Evasion? The Case Of Turkey, Robert W. Mcgee, Serkan Benk, Bahad?R Yüzba??, Tamer Budak

College of Business and Economics

This study surveys the opinion of a wide segment of Turkish society on the ethics of tax evasion. The survey instrument includes 18 statements used to justify tax evasion in the past. The research also finds that some reasons to justify tax evasion proved more attractive to participants than others. In our survey, the strongest support for tax evasion was in cases where the government abused human rights, where the government was corrupt or wasted tax funds, or where the taxpayer did not benefit from the tax expenditures. Conversely, the weakest arguments were in cases where the taxpayer did benefit …


Biol 368-H01: Ecology & Evolution Of Disease, Gareth Russell Sep 2020

Biol 368-H01: Ecology & Evolution Of Disease, Gareth Russell

Biology Syllabi

No abstract provided.


Neurological Care And Training In The Times Of Covid-19: A Tertiary Care Center Experience, Lubna Ashraf Jafri, Maryam Javed, Ali Sajjad, Dureshahwar Kanwar, Mohammad Wasay Sep 2020

Neurological Care And Training In The Times Of Covid-19: A Tertiary Care Center Experience, Lubna Ashraf Jafri, Maryam Javed, Ali Sajjad, Dureshahwar Kanwar, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

Resilience in these challenging times of COVID-19 at a professional and personal level is cardinal. Trainees and faculty have had to adapt to this adversity with striking limitations on formal neurological, neurovascular and neurophysiological residencies and fellowships. The revision of schedules and reallocation of assignments to cope with the practical aspects in a teaching tertiary care hospital have been overbearing. Novel structural innovation, testing, communications and supervision to assure a modified yet impactful training educational programme is mandatory and the need of the hour. Healthcare service providers remain at the highest risk of acquiring COVID-19 worldwide. Urgent measures to educate …


Venous Stroke Secondary To Varicella Zoster Virus Infection, Asma Akbar Ladak, Salman Farooq Sep 2020

Venous Stroke Secondary To Varicella Zoster Virus Infection, Asma Akbar Ladak, Salman Farooq

Pakistan Journal of Neurological Sciences (PJNS)

This is a case of cerebral venous sinus thrombosis (CVST) as a rare complication of varicella Zoster infection. A young male with no significant medical history presented with generalized tonic clonic seizures preceded by vesicular rash on the face diagnosed as Varicella zoster infection. The MRI showed bilaterial superficial hemorrhagic infarcts involving frontal and temporal lobes and MR Venogram was consistent with extensive CVST involving superioir sagittal, right transverse and superficial veins. After initial treatment with antiepileptic and anticoagulant, he showed marked improvement in symptomatology and made complete recovery subsequently with recanalization of sinuses seen on a follow up MRV …


Piloting And Evaluating Family-Centered Hiv Care In Eswatini, Caspian Chouraya, Nobuble Mthethwa, Lynne Mofenson, Philisiwe Khumalo, Lydia Mpango, Munamato Mirira, Rhoderick Machekano, Leila Katirayi, Kim Ashburn Sep 2020

Piloting And Evaluating Family-Centered Hiv Care In Eswatini, Caspian Chouraya, Nobuble Mthethwa, Lynne Mofenson, Philisiwe Khumalo, Lydia Mpango, Munamato Mirira, Rhoderick Machekano, Leila Katirayi, Kim Ashburn

HIV and AIDS

There are substantial gaps in essential services and numerous missed opportunities to engage children in care and provide effective HIV treatment. Although not new, family-centered care models that provide HIV services comprehensively to families as a unit, rather than providing separate services to children and adults, have the potential to address family needs and break down social, physical, and emotional barriers to accessing care. The family-centered care study (FAM-CARE) aims to contribute to our understanding of the role of family-centered care models (FCCM) in improving pediatric HIV outcomes in a sub-Saharan African setting.


Non-Fermenting Gram Negative Bacteria As Uropathogens In Causing Urinary Tract Infection And Its Antimicrobial Susceptibility Pattern At A Tertiary Care Centre Of South India, Anupam Berwal, K. L. Shobha, Rohit Gupta, Kriti Gupta Sep 2020

Non-Fermenting Gram Negative Bacteria As Uropathogens In Causing Urinary Tract Infection And Its Antimicrobial Susceptibility Pattern At A Tertiary Care Centre Of South India, Anupam Berwal, K. L. Shobha, Rohit Gupta, Kriti Gupta

Open Access archive

Non fermenting gram-negative bacilli (NFGNB) are recently striving as uropathogens. The present study was conducted to isolate the common species of bacteria in NFGNB causing urinary tract infection (UTI) and its correlation with comorbid conditions and to study the antibacterial susceptibility pattern. This retrospective study was done at the diagnostic Microbiology laboratory of a tertiary care hospital. Urine samples were collected for the period of six months. These samples were plated on blood agar and MacConkey agar and incubated at 37°C for 18–24 hr under aerobic conditions. Identification of NFGNB was done by Gram staining and MALDI-TOF (Matrix- Assisted Laser …


Characterization Of The Cazy Repertoire From The Marine-Derived Fungus Stemphylium Lucomagnoense In Relation To Saline Conditions, Wissal Ben Ali, David Navarro, Abhishek Kumar, Elodie Drula Sep 2020

Characterization Of The Cazy Repertoire From The Marine-Derived Fungus Stemphylium Lucomagnoense In Relation To Saline Conditions, Wissal Ben Ali, David Navarro, Abhishek Kumar, Elodie Drula

Open Access archive

Even if the ocean represents a large part of Earth’s surface, only a few studies describe marine-derived fungi compared to their terrestrial homologues. In this ecosystem, marine-derived fungi have had to adapt to the salinity and to the plant biomass composition. This articles studies the growth of five marine isolates and the tuning of lignocellulolytic activities under different conditions, including the salinity. A de novo transcriptome sequencing and assembly were used in combination with a proteomic approach to characterize the Carbohydrate Active Enzymes (CAZy) repertoire of one of these strains. Following these approaches, Stemphylium lucomagnoense was selected for its adapted …


Microglial Response To Aspergillus Flavus And Candida Albicans: Implications In Endophthalmitis, Jaishree Gandhi, Poonam Naik, Inderjeet Kaur, Ashok Kumar Sep 2020

Microglial Response To Aspergillus Flavus And Candida Albicans: Implications In Endophthalmitis, Jaishree Gandhi, Poonam Naik, Inderjeet Kaur, Ashok Kumar

Open Access archive

Aspergillus flavus is the most common etiology of fungal endophthalmitis in India, while Candida albicans is the causative agent in the West. In this study, we determined the role of microglial cells in evoking an inflammatory response following an infection with A. flavus and C. albicans strains isolated from patients with endophthalmitis. Microglia (CHME-3) cells were infected with A. flavus and C. albicans and the expression of Toll-Like Receptors (TLRs), cytokines and Matrix metalloproteinases (MMPs) were assessed at various time intervals. A. flavus infected cells induced higher expressions of TLR-1,-2,-5,-6,-7 and-9 and cytokines such as IL-1α, IL-6, IL-8, IL-10 and …


Recognition And Repetition Counting For Local Muscular Endurance Exercises In Exercise-Based Rehabilitation: A Comparative Study Using Artificial Intelligence Models, Ghanashyama Prabhu, Noel E. O’Connor, Kieran Moran Sep 2020

Recognition And Repetition Counting For Local Muscular Endurance Exercises In Exercise-Based Rehabilitation: A Comparative Study Using Artificial Intelligence Models, Ghanashyama Prabhu, Noel E. O’Connor, Kieran Moran

Open Access archive

Exercise-based cardiac rehabilitation requires patients to perform a set of certain prescribed exercises a specific number of times. Local muscular endurance exercises are an important part of the rehabilitation program. Automatic exercise recognition and repetition counting, from wearable sensor data, is an important technology to enable patients to perform exercises independently in remote settings, e.g., their own home. In this paper, we first report on a comparison of traditional approaches to exercise recognition and repetition counting (supervised ML and peak detection) with Convolutional Neural Networks (CNNs). We investigated CNN models based on the AlexNet architecture and found that the performance …


Unprotected On The Job: How Exclusion From Safety And Health Laws Harms California Domestic Workers, Isaac Jabola-Carolus Sep 2020

Unprotected On The Job: How Exclusion From Safety And Health Laws Harms California Domestic Workers, Isaac Jabola-Carolus

Publications and Research

Since its creation in 1973, California’s Occupational Safety and Health Act has excluded an entire class of workers—those employed in private households as nannies, housecleaners, home health aides, and home attendants. This report documents the human cost of their exclusion at a time when COVID-19 and ecological disaster compound typical workplace hazards. Based on a recent survey of over 700 domestic workers across the Los Angeles and San Francisco metropolitan areas, the report offers a large-scale snapshot of safety and health challenges faced by this workforce. Findings demonstrate that job-related injuries, illness, and violence are common; that employers rarely provide …


Analyses Of The Expression, Immunohistochemical Properties And Serodiagnostic Potential Of Schistosoma Japonicum Peroxiredoxin-4, Minh-Anh Dang-Trinh, Jose Ma. M. Angeles, Kharleezelle J. Moendeg, Adrian Miki C. Macalanda, Thu-Thuy Nguyen, Luna Higuchi, Shotaro Nakagun, Masahi Kirinoki, Yuichi Chigusa, Yasuyuki Goto, Shin-Ichiro Kawazu Sep 2020

Analyses Of The Expression, Immunohistochemical Properties And Serodiagnostic Potential Of Schistosoma Japonicum Peroxiredoxin-4, Minh-Anh Dang-Trinh, Jose Ma. M. Angeles, Kharleezelle J. Moendeg, Adrian Miki C. Macalanda, Thu-Thuy Nguyen, Luna Higuchi, Shotaro Nakagun, Masahi Kirinoki, Yuichi Chigusa, Yasuyuki Goto, Shin-Ichiro Kawazu

Biology Faculty Publications

Background

Schistosoma japonicum, which inhabits the mesenteric vein of the mammalian hosts for about 20 to 30 years, is subjected to the oxidative stresses from the host defense mechanism during their intra-mammalian stages. To counteract this host immune attack, the parasite utilizes their antioxidant system for survival inside the host. Peroxiredoxins (Prxs), thiol-specific antioxidant proteins, play an essential role for protecting the parasite against oxidative stress by reducing hydrogen peroxide to water. Only three types of 2-Cys Prxs have been previously characterized in S. japonicum whereas a fourth Prx has been identified for Schistosoma mansoni as Prx-4. A sequence …


Etiology Of Acute Undifferentiated Fever In Patients Presenting To The Emergency Department Of A Tertiary Care Center In Karachi, Pakistan, Noman Ali, Nadeem Ullah Khan, Shahid Shahid, Syed Mustahsan Sep 2020

Etiology Of Acute Undifferentiated Fever In Patients Presenting To The Emergency Department Of A Tertiary Care Center In Karachi, Pakistan, Noman Ali, Nadeem Ullah Khan, Shahid Shahid, Syed Mustahsan

Department of Emergency Medicine

Objective: Our study aimed at identifying the characteristics and etiology of various causes of acute undifferentiated fever in patients presenting to the emergency department of a tertiary care hospital.
Methods: This was a retrospective study conducted at the department of emergency medicine, Aga Khan University Hospital from January to June 2016. Adult patients presenting to Emergency department with acute undifferentiated fever were enrolled. Descriptive statistics were calculated in terms of mean±SD for continuous variables like age of the patients and duration of fever, whereas frequency and percentage were computed for categorical variables like gender and causes of fever.
Results: A …


Efficacy And Safety Of First-Line Avelumab In Patients With Advanced Non-Small Cell Lung Cancer: Results From A Phase Ib Cohort Of The Javelin Solid Tumor Study., Claire F Verschraegen, Guy Jerusalem, Edward F Mcclay, Nicholas Iannotti, Charles H Redfern, Jaafar Bennouna, Franklin L Chen, Karen Kelly, Janice Mehnert, John C Morris, Matthew H Taylor, David Spigel, Ding Wang, Hans Juergen Grote, Dongli Zhou, Neru Munshi, Marcis Bajars, James L Gulley Sep 2020

Efficacy And Safety Of First-Line Avelumab In Patients With Advanced Non-Small Cell Lung Cancer: Results From A Phase Ib Cohort Of The Javelin Solid Tumor Study., Claire F Verschraegen, Guy Jerusalem, Edward F Mcclay, Nicholas Iannotti, Charles H Redfern, Jaafar Bennouna, Franklin L Chen, Karen Kelly, Janice Mehnert, John C Morris, Matthew H Taylor, David Spigel, Ding Wang, Hans Juergen Grote, Dongli Zhou, Neru Munshi, Marcis Bajars, James L Gulley

Articles, Abstracts, and Reports

INTRODUCTION: Avelumab, an antiprogrammed death ligand-1 antibody, is approved as a monotherapy for treatment of metastatic Merkel cell carcinoma and advanced urothelial carcinoma, and in combination with axitinib for advanced renal cell carcinoma. We report the efficacy and safety of first-line avelumab in advanced non-small cell lung cancer (NSCLC).

METHODS: In a phase I expansion cohort of the JAVELIN Solid Tumor trial, patients with treatment-naive, metastatic, or recurrent NSCLC received 10 mg/kg avelumab intravenously every 2 weeks. Endpoints included best overall response, duration of response (DOR), progression-free survival (PFS), overall survival (OS), and safety.

RESULTS: Overall, 156 patients were enrolled …


Defining The Proteolytic Landscape During Enterovirus Infection., Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R Macdonald, John D Aitchison, Henrik Molina, Charles M Rice Sep 2020

Defining The Proteolytic Landscape During Enterovirus Infection., Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R Macdonald, John D Aitchison, Henrik Molina, Charles M Rice

Articles, Abstracts, and Reports

Viruses cleave cellular proteins to remodel the host proteome. The study of these cleavages has revealed mechanisms of immune evasion, resource exploitation, and pathogenesis. However, the full extent of virus-induced proteolysis in infected cells is unknown, mainly because until recently the technology for a global view of proteolysis within cells was lacking. Here, we report the first comprehensive catalog of proteins cleaved upon enterovirus infection and identify the sites within proteins where the cleavages occur. We employed multiple strategies to confirm protein cleavages and assigned them to one of the two enteroviral proteases. Detailed characterization of one substrate, LSM14A, a …


Quantifying Long-Term Health And Economic Outcomes For Survivors Of Group B Streptococcus Invasive Disease In Infancy: Protocol Of A Multi-Country Study In Argentina, India, Kenya, Mozambique And South Africa, Proma Paul, Simon R. Procter, Ziyaad Dangor, Quique Bassat, Amina Abubakar, Sridhar Santhanam, Romina Libster, Bronner P. Gonçalves, Shabir A. Madhi, Azucena Bardají Sep 2020

Quantifying Long-Term Health And Economic Outcomes For Survivors Of Group B Streptococcus Invasive Disease In Infancy: Protocol Of A Multi-Country Study In Argentina, India, Kenya, Mozambique And South Africa, Proma Paul, Simon R. Procter, Ziyaad Dangor, Quique Bassat, Amina Abubakar, Sridhar Santhanam, Romina Libster, Bronner P. Gonçalves, Shabir A. Madhi, Azucena Bardají

Institute for Human Development, East Africa

Sepsis and meningitis due to invasive group B Streptococcus (iGBS) disease during early infancy is a leading cause of child mortality. Recent systematic estimates of the worldwide burden of GBS suggested that there are 319,000 cases of infant iGBS disease each year, and an estimated 147,000 stillbirths and young-infant deaths, with the highest burden occurring in Sub-Saharan Africa. The following priority data gaps were highlighted: (1) long-term outcome data after infant iGBS, including mild disability, to calculate quality-adjusted life years (QALYs) or disability-adjusted life years (DALYs) and (2) economic burden for iGBS survivors and their families. Geographic data gaps were …


Vaccine Hesitancy: Experimentalism As Regulatory Opportunity, Ana Santos Rutschman, Timothy L. Wiemken Sep 2020

Vaccine Hesitancy: Experimentalism As Regulatory Opportunity, Ana Santos Rutschman, Timothy L. Wiemken

The Business, Entrepreneurship & Tax Law Review

This issue on patient innovation has prompted us to explore problems related to departures from official vaccination schedules. Vaccine confidence has been plummeting across the world. In this essay, we argue that a more granular understanding of vaccine hesitancy—and ultimately a more finely tuned regulatory framework—is needed to reflect the current behavioral heterogeneity among indicated patients who choose to forego or delay administration of recommended vaccines. In particular, we focus on a phenomenon we term “vaccine staggering:” a departure from vaccination schedules in the form of delays in receiving one or more vaccines, which is motivated by the desire to …


Interest In An Aviation Career After Covid-19, Abdul Muzill Bin Mohd Sukri, Muhammad Rusyaidi Arfan Bin Razali, Nurul Surfina Binte Mohamad Yazid, Zi Yi Tan Sep 2020

Interest In An Aviation Career After Covid-19, Abdul Muzill Bin Mohd Sukri, Muhammad Rusyaidi Arfan Bin Razali, Nurul Surfina Binte Mohamad Yazid, Zi Yi Tan

Introduction to Research Methods RSCH 202

We examine the impact of COVID-19 on the interest in a career in aviation. As countries close up borders to prevent further spreading, it has a negative impact such as reduced employment which can cause a lower interest in the aviation industry. Therefore, we are collecting surveys from academic institutions such as Junior College, Institute of Technical Education, Polytechnics, and Universities in Singapore. By utilizing the linear regression and Chi-square tests, we can examine how much COVID-19 affected the interest compared to other variables.


Neoantigen-Specific Cd4(+) T-Cell Response Is Critical For The Therapeutic Efficacy Of Cryo-Thermal Therapy, Peng Peng, Hong-Ming Hu, Ping Liu, Lisa X Xu Sep 2020

Neoantigen-Specific Cd4(+) T-Cell Response Is Critical For The Therapeutic Efficacy Of Cryo-Thermal Therapy, Peng Peng, Hong-Ming Hu, Ping Liu, Lisa X Xu

Articles, Abstracts, and Reports

Background: Traditional tumor thermal ablations, such as radiofrequency ablation (RFA) and cryoablation, can result in good local control of tumor, but traditional tumor thermal ablations are limited by poor long-term survival due to the failure of control of distal metastasis. Our previous studies developed a novel cryo-thermal therapy to treat the B16F10 melanoma mouse model. Long-term survival and T-cell-mediated durable antitumor immunity were achieved after cryo-thermal therapy, but whether tumor antigen-specific T-cells were augmented by cryo-thermal therapy was not determined.

Methods: The long-term antitumor therapeutic efficacy of cryo-thermal therapy was performed in B16F10 murine melanoma models. Splenocytes derived from mice …


Population-Level Covid-19 Mortality Risk For Non-Elderly Individuals Overall And For Non-Elderly Individuals Without Underlying Diseases In Pandemic Epicenters, John P.A. Ioannidis, Cathrine Axfors, Despina G. Contopoulos-Ioannidis Sep 2020

Population-Level Covid-19 Mortality Risk For Non-Elderly Individuals Overall And For Non-Elderly Individuals Without Underlying Diseases In Pandemic Epicenters, John P.A. Ioannidis, Cathrine Axfors, Despina G. Contopoulos-Ioannidis

All publications

Objective: To provide estimates of the relative rate of COVID-19 death in people < 65 years old versus older individuals in the general population, the absolute risk of COVID-19 death at the population level during the first epidemic wave, and the proportion of COVID-19 deaths in non-elderly people without underlying diseases in epicenters of the pandemic.

Eligible data: Cross-sectional survey of countries and US states with at least 800 COVID-19 deaths as of April 24, 2020 and with information on the number of deaths in people with age < 65. Data were available for 14 countries (Belgium, Canada, France, Germany, India, Ireland, Italy, Mexico, Netherlands, Portugal, Spain, Sweden, Switzerland, UK) and 13 US states (California, Connecticut, Florida, Georgia, Illinois, Indiana, Louisiana, Maryland, Massachusetts, Michigan, New Jersey, New York, Pennsylvania). We also examined available data on COVID-19 deaths in people with age

Main outcome measures: Proportion of COVID-19 deaths in people < 65 years old; relative mortality rate of COVID-19 death in people < 65 versus ≥ 65 years old; absolute risk of COVID-19 death in people < 65 and in those ≥ 80 years old in the general population as of June 17, 2020; absolute COVID-19 mortality rate expressed as equivalent of mortality rate from driving a motor vehicle.

Results: Individuals with age < 65 account for 4.5–11.2% of all COVID-19 deaths in European countries and Canada, 8.3–22.7% in the US locations, and were the majority in India and Mexico. People < 65 years old had 30- to 100-fold lower risk of COVID-19 death than those ≥ 65 years old in 11 European countries and Canada, 16- to 52-fold lower risk in US locations, and less than 10-fold in India and Mexico. The absolute risk of COVID-19 death as of June 17, 2020 for people < 65 years old in high-income countries ranged from 10 (Germany) to 349 per million (New Jersey) and it was 5 per million in India and 96 per million in Mexico. The absolute risk of COVID-19 death for people ≥ 80 years old ranged from 0.6 (Florida) to 17.5 per thousand (Connecticut). The COVID-19 mortality rate in people < 65 years old during the period of fatalities from the epidemic was equivalent to the mortality rate from driving between 4 and 82 miles per day for 13 countries and 5 states, and was higher (equivalent to the mortality rate from driving 106–483 miles per day) for 8 other states and the UK. People < 65 years old without underlying predisposing conditions accounted for only 0.7–3.6% of all COVID-19 deaths in France, Italy, Netherlands, Sweden, Georgia, and New York City and 17.7% in Mexico.

Conclusions: People < 65 years old have very small risks of COVID-19 death even in pandemic epicenters and deaths for people < 65 years without underlying predisposing conditions are remarkably uncommon. Strategies focusing specifically on protecting high-risk elderly individuals should be considered in managing the pandemic.


Caring For Vulnerable Populations During A Pandemic: Literature Review, Jennifer L. Marsh, Marilyn O'Mallon, Steven Stockdale, Danita R. Potter Sep 2020

Caring For Vulnerable Populations During A Pandemic: Literature Review, Jennifer L. Marsh, Marilyn O'Mallon, Steven Stockdale, Danita R. Potter

Nursing Faculty Publications and Presentations

Vulnerable populations account for a substantial proportion of the United States population. The current COVID-19 pandemic has highlighted the elderly and those with underlying health issues as having the highest risk of mortality. This literature review utilizes a matrix approach to explore the challenges to providing care for the vulnerable elderly, those with underlying health issues, with disabilities, with low income or homelessness, and those with mental health concerns in these extreme times. Appropriate care for vulnerable populations in times of crisis requires focus and planning in critical areas. This article discusses the critical areas of communications and trust, policies …


How Do I Manage Long-Term Blood Component Shortages In A Hospital Transfusion Service, Claudia S. Cohn, Monica B. Pagano, Elizabeth S. Allen, Kathrine P. Frey, Thomas Gniadek, Parvez M. Lokhandwala, Colin H. Murphy, Jay S. Raval, Nancy M. Dunbar Sep 2020

How Do I Manage Long-Term Blood Component Shortages In A Hospital Transfusion Service, Claudia S. Cohn, Monica B. Pagano, Elizabeth S. Allen, Kathrine P. Frey, Thomas Gniadek, Parvez M. Lokhandwala, Colin H. Murphy, Jay S. Raval, Nancy M. Dunbar

Pathology Research and Scholarship

INTRODUCTION Temporary blood component shortages are common in some areas of the United States (US) and can usually be managed with short-term solutions.1However, a widespread, long-term shortage that leaves the blood industry with insufficient blood components to serve urgent medical needs requires additional mitigation strategies. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused the Coronavirus Disease 2019 (COVID-19) pandemic represents the greatest threat to the blood supply in recent memory. If the COVID-19 pandemic continues unchecked, the downward trend in blood collections will likely con-tinue.2Hospital transfusion services may be faced with unprecedented long-term shortages in blood products. A …


Guidance For Contemporary Use Of Biologics In Management Of Chronic Rhinosinusitis With Nasal Polyps: Discussion From A National Institutes Of Health-Sponsored Workshop, Lauren T Roland, Timothy L Smith, Rodney J Schlosser, Zachary M Soler, Anju T Peters, Tanya M Laidlaw, Benjamin S Bleier, Vijay Ramakrishnan, Elina Toskala, David W Kennedy, Amber U Luong Sep 2020

Guidance For Contemporary Use Of Biologics In Management Of Chronic Rhinosinusitis With Nasal Polyps: Discussion From A National Institutes Of Health-Sponsored Workshop, Lauren T Roland, Timothy L Smith, Rodney J Schlosser, Zachary M Soler, Anju T Peters, Tanya M Laidlaw, Benjamin S Bleier, Vijay Ramakrishnan, Elina Toskala, David W Kennedy, Amber U Luong

Faculty, Staff and Student Publications

BACKGROUND: Biologic medications are emerging as options for treating chronic rhinosinusitis with nasal polyps (CRSwNP). Several questions remain regarding patient selection, indications, clinical efficacy, and cost effectiveness.

METHODS: In November 2019, a group of physicians and scientists gathered to consider strategies for future studies regarding biologics. During the discussion, gaps in knowledge highlighted a need for a consensus on the present day use of biologics in polyp patients.

RESULTS: The goal of this guideline is to propose recommendations for the current use of biologics in CRSwNP as new evidence continues to emerge and inform practice.

CONCLUSION: We suggest that physicians …


Fever Time Series Analysis Using Slope Entropy. Application To Early Unobtrusive Differential Diagnosis, David Cuesta-Frau, Pradeepa H. Dakappa, Chakrapani Mahabala, Arjun R. Gupta Sep 2020

Fever Time Series Analysis Using Slope Entropy. Application To Early Unobtrusive Differential Diagnosis, David Cuesta-Frau, Pradeepa H. Dakappa, Chakrapani Mahabala, Arjun R. Gupta

Open Access archive

Fever is a readily measurable physiological response that has been used in medicine for centuries. However, the information provided has been greatly limited by a plain thresholding approach, overlooking the additional information provided by temporal variations and temperature values below such threshold that are also representative of the subject status. In this paper, we propose to utilize continuous body temperature time series of patients that developed a fever, in order to apply a method capable of diagnosing the specific underlying fever cause only by means of a pattern relative frequency analysis. This analysis was based on a recently proposed measure, …


Zoonotic Diseases: Etiology, Impact, And Control., Md. Tanvir Rahman, Md. Abdus Sobur, Md. Saiful Islam, Samina Ievy, Md. Jannat Hossain, Mohamed E El Zowalaty, Amm Taufiquer Rahman, Hossam M Ashour Sep 2020

Zoonotic Diseases: Etiology, Impact, And Control., Md. Tanvir Rahman, Md. Abdus Sobur, Md. Saiful Islam, Samina Ievy, Md. Jannat Hossain, Mohamed E El Zowalaty, Amm Taufiquer Rahman, Hossam M Ashour

All publications

Most humans are in contact with animals in a way or another. A zoonotic disease is a disease or infection that can be transmitted naturally from vertebrate animals to humans or from humans to vertebrate animals. More than 60% of human pathogens are zoonotic in origin. This includes a wide variety of bacteria, viruses, fungi, protozoa, parasites, and other pathogens. Factors such as climate change, urbanization, animal migration and trade, travel and tourism, vector biology, anthropogenic factors, and natural factors have greatly influenced the emergence, re-emergence, distribution, and patterns of zoonoses. As time goes on, there are more emerging and …


What Will It Take To Implement Health And Health-Related Sustainable Development Goals?, Zulfiqar Ahmed Bhutta, Sameen Siddiqi, Wafa Aftab, Fahad Javaid Siddiqui, Luis Huicho, Roman Mogilevskii, Qamar Mahmood, Peter Friberg, Fawad Akbari Sep 2020

What Will It Take To Implement Health And Health-Related Sustainable Development Goals?, Zulfiqar Ahmed Bhutta, Sameen Siddiqi, Wafa Aftab, Fahad Javaid Siddiqui, Luis Huicho, Roman Mogilevskii, Qamar Mahmood, Peter Friberg, Fawad Akbari

Woman and Child Health

No abstract provided.


Foundations Of An Outpatient Antibiotic Stewardship Program, Brian Stello Md, Eric T. Young Md, Jarrod W. Kile Rphd, Timothy J. Friel Md, Grant M. Greenberg M.D., M.H.S.A., M.A., Tibisay Villalobos Md, Kristin M. Held-Wheatley Pharmd, Bcop, Katarzyna Jabbour Pharmd, Bcps, Kathryn Zaffiri Mph Sep 2020

Foundations Of An Outpatient Antibiotic Stewardship Program, Brian Stello Md, Eric T. Young Md, Jarrod W. Kile Rphd, Timothy J. Friel Md, Grant M. Greenberg M.D., M.H.S.A., M.A., Tibisay Villalobos Md, Kristin M. Held-Wheatley Pharmd, Bcop, Katarzyna Jabbour Pharmd, Bcps, Kathryn Zaffiri Mph

Department of Family Medicine

No abstract provided.


Mapping Geographical Inequalities In Access To Drinking Water And Sanitation Facilities In Low-Income And Middle-Income Countries, 2000–17, Aniruddha Deshpande, Robert C. Reiner Jr, Veincent Christian F. Pepito, Arianna Maever L. Amit, Local Burden Of Disease Wash Collaborators, 665 Co-Authors Sep 2020

Mapping Geographical Inequalities In Access To Drinking Water And Sanitation Facilities In Low-Income And Middle-Income Countries, 2000–17, Aniruddha Deshpande, Robert C. Reiner Jr, Veincent Christian F. Pepito, Arianna Maever L. Amit, Local Burden Of Disease Wash Collaborators, 665 Co-Authors

Ateneo School of Medicine and Public Health Publications

Background

Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinking water and sanitation facilities.

Methods

We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and aggregated results to policy-relevant …