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October 29, 2020: Letter From The President- Covid-19 Update, Kettering University

Communication Updates

No abstract provided.

Risk Factors For Delayed Viral Suppression On First-Line Antiretroviral Therapy Among Persons Living With Hiv In Haiti, 2013-2017, Shannan N. Rich, Robert L. Cook, Lusine Yaghjyan, Kesner Francois, Nancy Puttkammer, Ermane Robin, Jungjun Bae, Nadjy Joseph, Luisa Pessoa-Brandão, Chris Delcher

Institute for Pharmaceutical Outcomes and Policy Faculty Publications

Studies of viral suppression on first-line antiretroviral therapy (ART) in persons living with human immunodeficiency virus (PLHIV) in Haiti are limited, particularly among PLHIV outside of the Ouest department, where the capital Port-au-Prince is located. This study described the prevalence and risk factors for delayed viral suppression among PLHIV in all geographic departments of Haiti between 2013 and 2017. Individuals who received viral load testing 3 to 12 months after ART initiation were included. Data on demographics and clinical care were obtained from the Haitian Active Longitudinal Tracking of HIV database. Multivariable logistic regression was performed to predict delayed viral …

Interdisciplinary Work Highlighted At Covid-19 Research Symposium, Jeff Hansen

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No abstract provided.

Comparable Human Reconstitution Following Cesium-137 Versus X-Ray Irradiation Preconditioning In Immunodeficient Nog Mice, Anna Halling Folkmar Andersen, Stine Sofie Frank Nielsen, Rikka Olesen, Jakob Le Fèvre Harslund, Ole S. Søgaard, Lars Østergaard, Paul Denton, Martin Tolstrup

Biology Faculty Publications

Humanized mouse models are used extensively in research involving human pathogens and diseases. However, most of these models require preconditioning. Radio-active sources have been used routinely for this purpose but safety issues have motivated researchers to transition to chemical or X-ray based preconditioning. In this study, we directly compare 350 kV X-ray and Cs-137 low-dose precondition of NOG mice before human stem cell transplantation. Based on flow cytometry data, we found that engraftment of human cells into the mouse bone marrow was similar between radiation sources. Likewise, human engraftment in the peripheral blood was comparable between Cs-137 and three different …

Evaluation Of Semi-Quantitative Compared To Quantitative Cultures Of Tracheal Aspirates For The Yield Of Culturable Respiratory Pathogens - A Cross-Sectional Study, Salima Rattani, Joveria Farooqi, Ghazala Jabeen, Saeeda Chandio, Qaiser Kash, Aijaz Khan, Kauser Jabeen

Department of Pathology and Laboratory Medicine

Background: Diagnosis of lower respiratory tract infections (LRTI) depends on the presence of clinical, radiological and microbiological findings. Endotracheal suction aspirate (ETSA) is the commonest respiratory sample sent for culture from intubated patients. Very few studies have compared quantitative and semi-quantitative processing of ETSA cultures for LRTI diagnosis. We determined the diagnostic accuracy of quantitative and semi-quantitative ETSA culture for LRTI diagnosis, agreement between the quantitative and semi quantitative culture techniques and the yield of respiratory pathogens with both methods.
Methods: This was a cross-sectional study conducted at the Aga Khan University clinical laboratory, Karachi, Pakistan. One hundred and seventy-eight …

Optical Density Optimization Of Malaria Pan Rapid Diagnostic Test Strips For Improved Test Zone Band Intensity, Prince Manta, Rupak Nagraik, Avinash Sharma, Akshay Kumar, Pritt Verma, Shavran Kumar Paswan, Dmitry O. Bokov, Juber Dastagir Shaikh, Roopvir Kaur, Ana Francesca Vommaro Leite, Silas Jose Braz Filho, Nimisha Shiwalkar, Purnadeo Persaud, Deepak N. Kapoor

Student Publications

For the last few decades, the immunochromatographic assay has been used for the rapid detection of biological markers in infectious diseases in humans and animals The assay, also known as lateral flow assay, is utilized for the detection of antigen or antibody in human infectious diseases. There are a series of steps involved in the development of these immuno-chromatographic test kits, from gold nano colloids preparation to nitrocellulose membrane coating (NCM). These tests are mostly used for qualitative assays by a visual interpretation of results. For the interpretation of the results, the color intensity of the test zone is therefore …

The Boilerworx Project: Mobile Public Health Advocacy, Carolanne Wartman, Kevin Fekete, Fatima Khan, Carrie Kovacik, Carol Ott, Nicole Noel, Catherine Scott

Purdue Journal of Service-Learning and International Engagement

BoilerWoRx is a mobile health initiative that was created in response to Indiana's opioid public health crisis. This College of Pharmacy program is multidisciplinary with students from engineering, nursing, liberal arts, and medicine. BoilerWoRx offers education to both students and community members. There is a comprehensive training for students who volunteer with the BoilerWoRx team, which include various educational Ted Talks, naloxone training, along with assessment tool trainings. For the community members at the events, drug disposal kits, wellness education, syringe service assistance, naloxone distribution, mental health assessments, and community resources are available.

Currently, BoilerWoRx is working with engineering students …

Student Pharmacists Bridging The Gap With Community Partnerships: Purdue University College Of Psychiatric And Neurologic Pharmacists Chapter, Fatima A. Khan, Elise M. Mann

Purdue Journal of Service-Learning and International Engagement

The CPNP Purdue chapter is a student organization that strives to advance mental health awareness and education, reduce stigma, and volunteer in the local community. CPNP Purdue is strengthened by collaboration with partner organizations, including the National Alliance on Mental Illness (NAMI) and Home with Hope, a Lafayette-based recovery housing center. NAMI advocates for effective treatment and education for families affected by mental illness in the surrounding community. Home with Hope provides a continuum of care and environment conducive to recovery following treatment for substance use disorders. These nonprofit partnerships rely heavily upon volunteers, donations, and advocates to provide services …

Development Of “Sharkavir”: A New Hypothetical Inhibitor For Hiv-1 Protease, Feza Abbas

Trick to the Treat of Internships and Research

HIV has infected approximately 37 million people worldwide and results in over 1 million deaths annually. A key component of the HIV life cycle is the enzyme HIV-1 protease, which is involved in cutting newly made protein components of the HIV virion. Our research focused on how can molecular models be used to simulate the binding of various HIV-1 prtease inhibitors including Darunavir, Ritonavir, and a novel combination of these two named "Sharkavir".

Covid-19 Research Symposium Engages Over 2k Participants; Highlights Outstanding Research At Uab, Mary Ashley Canevaro

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No abstract provided.

2020-10-28_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Uab's Rachael Lee, M.D., Answers More Of Your Covid-19 Questions, Adam Pope

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No abstract provided.

Fauci, Neuzil Address Uab At Covid-19 Research Symposium, Tyler Greer

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No abstract provided.

Adversity In Childhood Is Linked To Mental And Physical Health Throughout Life, Charles A. Nelson, Richard David Scott, Zulfiqar Ahmed Bhutta, Nadine Burke Harri, Andrea Danes, Muthanna Samara

Woman and Child Health

The prevalence of “toxic stress” and huge downstream consequences in disease, suffering, and financial costs make prevention and early intervention crucial, say Charles A Nelson and colleagues.

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Salmonella Meningitis Complicated By Ventriculitis And Brain Abscesses In An Hiv Positive Adult Patient, Tamoor Ahmed, Taha Ahmed

Internal Medicine Faculty Publications

Salmonella meningitis is a rare complication of Salmonella sepsis and is mostly reported in infants and young children. The incidence of Salmonella bacteremia is increased in immunocompromised adult individuals, such as those having human immunodeficiency virus (HIV) infection. Ventriculitis and brain abscess as a complication of Salmonella intracranial infection is particularly rare, even in patients who are immunosuppressed. Herein, we report a case of Salmonella meningitis complicated by ventriculitis and two brain abscesses in an HIV positive adult patient requiring mini-craniectomy and drainage along with a prolonged course of antibiotic therapy with a favorable outcome.

Preparedness, Agility, And The Philippine Response To The Covid-19 Pandemic: The Early Phase In Comparative Southeast Asian Perspective, Filomeno V. Aguilar Jr.

Philippine Studies: Historical and Ethnographic Viewpoints

Was the Philippines prepared for the Covid-19 pandemic? Did the government take early and effective action that can be characterized as strategically agile? Thisarticle answers these questions by reconstructing the chronology of the Philippine government’s response to the pandemic during the early phase. It focuses on three issues: virus importation (specifically the first Covid-19 case), testing, and contact tracing. The Philippine response is contrasted with those of Thailand and Vietnam, which, unlike the Philippines, have succeeded in lowering per capita mortality rate. Deficient in strategic agility, the Philippines failed to consider early on a scenario of extreme disease outbreak. KEYWORDS: …

Duterte’S Disciplinary Quarantine: How A Moral Dichotomy Was Constructed And Undermined, Wataru Kusaka

Philippine Studies: Historical and Ethnographic Viewpoints

Thisarticle explores the characteristics of what I call Duterte’s “disciplinary quarantine,” which is premised on a moral dichotomy between “good citizens,” who abide by strict regulations, and undisciplined “evil others” (pasaway), who endanger the nation. Based on my family’s participant observation in Bohol, thisarticle also describes how Boholanos have undermined the moral dichotomy by embracing minor violations to endure the government’s protracted and rigid quarantine rules. I suggest that ideas about appropriate behaviors created through people’s mutuality and everyday trials and errors are more reliable than top-down “discipline” for a continual struggle against the pandemic. KEYWORDS: DISCIPLINE • MORAL DICHOTOMY …

The Penalty Of Mobility In Manila During Periods Of Public Health Crises, Michael D. Pante

Philippine Studies: Historical and Ethnographic Viewpoints

Mobility seems to impose a paradoxical penalty on individuals based in Metro Manila. Looking at the experiences of public health crises during the American colonial period and the present-day Covid-19 pandemic, this essay focuses on the inordinate restrictions on and blame assigned to the least mobile segments of the population despite the fact that such crises are aided by heightened mobility. Past and present disease outbreaks force us to acknowledge that our cities contain groups of people with varying levels of mobility, another form of social inequality that badly needs to be addressed. KEYWORDS: TRANSPORTATION • URBANIZATION • CITIES • …

Beyond The Pathogen: Cultural Influences On The Impact Of Epidemics Viewed From History, Linda A. Newson

Philippine Studies: Historical and Ethnographic Viewpoints

The paper reflects on the historical experience of epidemics in Latin America and the Philippines. It shows how cultural factors can affect the ability of societies to develop immunity and recover. It also shows how leadership can influence the way in which an epidemic and the health crisis is managed. As such, it argues that the impact of a single epidemic is unlikely to be the same throughout the world or even within one country. KEYWORDS: HISTORY OF EPIDEMICS • CULTURE AND DEMOGRAPHY • LEADERSHIP • LATIN AMERICA • PHILIPPINES

The Philippine Covidscape: Colonial Public Health Redux?, Warwick Anderson

Philippine Studies: Historical and Ethnographic Viewpoints

Comparing historical perceptions of three epidemics in the Philippines and the responses they elicited allows us to see how these disease outbreaks were conceived in terms of configuration, whether ecological or sociological, and contamination. Cholera in 1902, influenza in 1918–1919, and Covid-19 in 2020 each open up revealing cross sections through Philippine social life, culture, and governance. Furthermore, simplistic assumptions of contamination or pollution—in contrast to more complexly structured configurational models—are correlated with coercive or militaristic reactions to pandemics, including social distancing, lockdowns, curfews, and suppression of dissent. KEYWORDS: MEDICINE • SCIENCE • HISTORY • CHOLERA • INFLUENZA • COVID-19

The Severe Acute Respiratory Syndrome (Sars) Outbreak In The Philippines In 2003, Gideon Lasco

Philippine Studies: Historical and Ethnographic Viewpoints

The global outbreak of Severe Acute Respiratory Syndrome (SARS) dominated public discourse in the Philippines from March to May 2003. But, given the scale of its impact and the range of responses it elicited, it largely escaped documentation, likely owing to its abbreviated timeframe and the overall lack of scholarly attention to contemporary medical crises. Thisarticle reconstructs the “outbreak narrative” of SARS and the perceptions and practices that surrounded it. It discusses points of comparison between SARS and the Covid-19 pandemic, underscoring that many practices seen in both events are familiar, not exceptional, responses to health crises in the country. …

Science And Public Service During A Pandemic: Reflections From The Scientists Of The Philippine Government’S Covid-19 Surveillance Platform, Maria Regina Estuar, Joshua Uyheng, Marlene De Leon, Daniel Joseph Benito, Elvira De Lara-Tuprio, Carlo Estadilla, Timothy Teng

Philippine Studies: Historical and Ethnographic Viewpoints

During the Covid-19 pandemic, science plays an important role in understanding and intervening in local outbreaks. Conducting scientific operations for pandemic response also takes on unique human and social dimensions. Reflexivity is often a key to understanding the perspectives that scientists take in applying theory to practice. In this essay we share that reflexivity by detailing personal reflections as scientists of FASSSTER, an integrated platform providing scientific intelligence to the Philippine government for monitoring and responding to the Covid-19 outbreak in the country. KEYWORDS: COVID-19 • SCIENCE–POLICY INTERACTIONS •DISEASE SURVEILLANCE • BOUNDARY WORK • ACTION RESEARCH

Rapidly Declining Body Temperature In A Tropical Human Population, Michael Gurven, Thomas Kraft, Sarah Alami, Juan Copajira Adrian, Edhitt Cortez Linares, Daniel Cummings, Daniel Eid Rodriguez, Paul L. Hooper, Adrian Jaeggi, Raul Quispe Gutierrez, Ivan Maldonado Suarez, Edmond Seabright, Hillard Kaplan, Jonathan Stieglitz, Benjamin C. Trumble

ESI Publications

Normal human body temperature (BT) has long been considered to be 37.0°C. Yet, BTs have declined over the past two centuries in the United States, coinciding with reductions in infection and increasing life expectancy. The generality of and reasons behind this phenomenon have not yet been well studied. Here, we show that Bolivian forager-farmers (n = 17,958 observations of 5481 adults age 15+ years) inhabiting a pathogen-rich environment exhibited higher BT when first examined in the early 21st century (~37.0°C). BT subsequently declined by ~0.05°C/year over 16 years of socioeconomic and epidemiological change to ~36.5°C by 2018. As predicted, …

Research News. Publications, 2020. Volume 3, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through September 30, 2020

Comparing Intervention Strategies For Reducing Clostridioides Difficile Transmission In Acute Healthcare Settings: An Agent-Based Modeling Study, Brittany Stephenson, Cristina Lanzas, Suzanne Lenhart, Eduardo Ponce, Jason Bintz, Erik R Dubberke, Judy Day

2020-Current year OA Pubs

BACKGROUND: Clostridioides difficile infection (CDI) is one of the most common healthcare infections. Common strategies aiming at controlling CDI include antibiotic stewardship, environmental decontamination, and improved hand hygiene and contact precautions. Mathematical models provide a framework to evaluate control strategies. Our objective is to evaluate the effectiveness of control strategies in decreasing C. difficile colonization and infection using an agent-based model in an acute healthcare setting.

METHODS: We developed an agent-based model that simulates the transmission of C. difficile in medical wards. This model explicitly incorporates healthcare workers (HCWs) as vectors of transmission, tracks individual patient antibiotic histories, incorporates varying …

Implication Of Infrastructure Development On Rural Women’S Welfare: Case Of Uzbekistan, Nodira Mannapovna Azizova, Lobarkhon Kadirjanovna Azizova

Scientific reports of Bukhara State University

Background. Lack of water supply and sanitation infrastructure in rural areas affects people’s health, welfare and living conditions, negatively impacts the rural environment, and can stall rural development and prosperity. Improving equitable and sustainable access to safe and improved water supply and sanitation in rural areas is therefore an important national development objective. This article presents to what extend the welfare level of the rural women in Uzbekistan correlates with socio-economic factors such as access to water supply and sanitation services in Uzbekistan. Methods. This article is based on comparative analysis of the gender aspects of welfare of rural women …

October 27, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …

Ua12/2/1 College Heights Herald, Vol. 96, No. 10, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Nutter, Abbey. Haunting on the Hill
• Latimer, Jacob. Campus Community Expresses Their Thoughts on Buildings & Colleges Connected to Slave Owners
• Collins, Michael. Greek Organizations Under Scrutiny for COVID-19 Violations
• Cox, Alex. Editorial Cartoon re: Body Image
• College Diet Culture
• Frazier, Keilen & Anna Leachman. Carving New Paths – Southwest Kentucky Mountain Bike Association
• E-Sports Explained
• Gaylord, Kaden. Nothing to Celebrate About That Win – Football
• Hargrove, Matthew. Tyrell Pigrome’s Late Touchdown Gives Hilltoppers First Win in Two Weeks – Football

2020-10-27_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …