Digital Commons Network^™

Characterization Of Glycan Determinants That Mediate Recognition Of The Major Wuchereria Bancrofti Circulating Antigen By Diagnostic Antibodies, Marla I Hertz, Amy Rush, Thomas B Nutman, Gary J Weil, Sasisekhar Bennuru, Philip J Budge

2020-Current year OA Pubs

The Global Program to Eliminate Lymphatic Filariasis (GPELF) relies heavily on a rapid diagnostic test (RDT) to a Wuchereria bancrofti circulating filarial antigen (Wb-CFA) to identify endemic areas and for determining when mass drug administration can stop. The antigen contains a carbohydrate epitope that is recognized by monoclonal antibody AD12. Og4C3, a monoclonal antibody that is used in a commercial ELISA for Wb-CFA recognizes the same moiety. Despite its diagnostic importance, little is known about the structure and function of this "AD12 epitope". It is also present on other W. bancrofti glycoproteins and on glycoproteins of other filarial worms, but …

Management Of Multisystem Inflammatory Syndrome In Children Associated With Covid-19: A Survey From The International Kawasaki Disease Registry., Matthew D. Elias, Brian W. Mccrindle, Guillermo Larios, Nadine F. Choueiter, Nagib Dahdah, Ashraf S. Harahsheh, Supriya Jain, Cedric Manlhiot, Michael A. Portman, Geetha Raghuveer, Therese M. Giglia, Audrey Dionne, International Kawasaki Disease Registry

Manuscripts, Articles, Book Chapters and Other Papers

Background: Since April 2020, there have been numerous reports of children presenting with systemic inflammation, often in critical condition, and with evidence of recent infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This condition, since defined as the multisystem inflammatory syndrome in children (MIS-C), is assumed to be a delayed immune response to coronavirus disease 2019 (COVID-19), and there are frequently cardiac manifestations of ventricular dysfunction and/or coronary artery dilation.

Methods: We surveyed the inpatient MIS-C management approaches of the members of the International Kawasaki Disease Registry across 38 institutions and 11 countries.

Results: Among the respondents, 56% reported …

"Some Statistical Data On Urban Waste Collection In The City Of Prizren And Ways To Evaluate Them In Useful Products", Sami Gashi, Besa Veseli, Vehebi Sofiu

UBT International Conference

The development of society is related to the high consumption of a variety of food products, the use of electro-household appliances, furniture, and its furnishing, clothing, plastic materials, etc. The increase of urban waste is considered both from the social development and the increase of the population, for example, Prishtina 1,116,355 tons/year, Prizren 90,858 tons/year, Peja 41,748 tons/year, Mitrovica 64,663 tons/year. The increase in urban waste will affect our environment (soil, water, and air). Even though our city is endangered by their lack of treatment, their quantity is constantly increasing. We need to change the concept that waste is worthless. …

Investigational Anti Sars-Covid 19 Medication, Gazmend Temaj, Kumrije Sopi Xharra, Shefki Xharra, Angelika Moder, Jasmin Nurkovic, Hilada Hefic, Rifat Hadziselimovic

UBT International Conference

The newly identified severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) that originated in December 2019 in Wuhan, China. By July 2020, the WHO reported over 17 million confirmed cases in over 200 countries around the globe. This review discusses how the COVID-19 pandemic may affect healthy people, structure and replication cycle of SARS- CoV-2; targets and therapeutics SARS- CoV-2 and anti-COVID drugs: strategies and perspectives.

Pharmacogenetics- Gene And Sars-Covid 19 Medication, Gazmend Temaj, Kumrije Sopi Xharra, Shefki Xharra, Angelika Moder, Jasmin Nurkovic, Hilada Hefic, Hilada Hefic, Rifat Hadziselimovic

UBT International Conference

An analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes collected from the patients worldwide has identified mutations in the virus that could aid in drug and vaccine development. The researchers found that the virus’s genetic diversity in most countries is similar to what it is globally, suggesting that it was introduced repeatedly by many infected people in each country rather than by a “patient zero.” The genetic analysis found 198 mutations that have occurred more than once. “Mutations in themselves are not a bad thing it is nothing to suggest SARS-CoV-2 is mutating faster or slower than expected. …

Attitudes Of Citizens Of The Republic Of Kosovo And The Identification Of Overcoming Mechanisms During The Covid-19-Coronavirus Period, Nausika Hoxha

UBT International Conference

The purpose of the research is to identify the overcoming mechanisms to citizens of Kosovo and how they feel during the quarantine. The research was conducted with quantitative design and 1053 participants, variated age 19-65, while the administration of the non- standardized questionnaire was online and consisted of 22 questions and 3 of them were opened questions. The analysis of the data was performed depending on the frequency obtained from the results of the online platform in a descriptive form, by which a questionnaire was administered where they present the percentages and graphs from the answers of the participants. The …

2020-10-31_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

One Out Of Ten: Low Sampling Efficiency Of Cloth Dragging Challenges Abundance Estimates Of Questing Ticks, Siiri Nyrhilä, Jani J. Sormunen, Satu Mäkelä, Ella Sippola, Eero J. Vesterinen, Tero Klemola

Harold W. Manter Laboratory of Parasitology: Library Materials

Hard ticks (Acari: Ixodidae) act as important vectors of zoonotic pathogens. For instance, Borrelia burgdorferi s.l. spirochetes pose a severe health risk as aetiological agents of Lyme borreliosis. Commonly, to study the abundance of questing (host-seeking) ticks, a 1 m2 piece of cloth is dragged over vegetation for a determined distance. Here, we designed a tick-sampling study to estimate the sampling efficiency of this standard method. We established 10 m dragging transects in a hemiboreal mixed forest patch in SW Finland for a 5-day monitoring period. Five of the transects were cloth-dragged 3× a day, whereas another five transects were …

A Hybrid Agent-Based And Equation Based Model For The Spread Of Infectious Diseases, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

Both agent-based models and equation-based models can be used to model the spread of an infectious disease. Equation-based models have been shown to capture the overall dynamics of a disease outbreak while agent-based models are able to capture heterogeneous characteristics of agents that drive the spread of an outbreak. However, agent-based models are computationally intensive. To capture the advantages of both the equation-based and agent-based models, we create a hybrid model where the disease component of the hybrid model switches between agent-based and equation-based. The switch is determined using the number of agents infected. We first test the model at …

Prognostic Value Of Hla-I Homozygosity In Patients With Non-Small Cell Lung Cancer Treated With Single Agent Immunotherapy, Afaf Abed, Leslie Calapre, Johnny Lo, Suzana Correia, Samantha Bowyer, Abha Chopra, Mark Watson, Muhammad A. Khattak, Michael Millward, Elin Solomonovna Gray

Research outputs 2014 to 2021

Background We aimed to assess the impact of genomic human leukocyte antigen (HLA)-I/II homozygosity on the survival benefit of patients with unresectable locally advanced, metastatic non-small lung cancer treated by single-agent programmed cell death protein-1/programmed death ligand 1 (PD1/PDL1) inhibitors.

Methods We collected blood from 170 patients with advanced lung cancer treated with immunotherapy at two major oncology centers in Western Australia. Genomic DNA was extracted from white blood cells and used for HLA-I/II high-resolution typing. HLA-I/II homozygosity was tested for association with survival outcomes. Univariable and multivariable Cox regression models were constructed to determine whether HLA homozygosity was an …

Antibacterial Activities Of The Extracts Of Allium Sativum (Garlic) And Allium Cepa (Onion) Against Selected Pathogenic Bacteria, Sherifat O. Enejiyon, Al-Hassan A. Abdulrahman, Abdulameen S. Adedeji, Ramatu Abdulsalam, Mary U. Oyedum

Tanzania Journal of Science

Although many antibiotics have been developed against bacterial diseases, the problems of antibiotic resistance and toxicity have made the continuous search for newer drugs an existential necessity. This study determined the phytochemical components and antibacterial activities of Allium sativum and Allium cepa against Salmonella typhi, Staphylococcus aureus, Streptococcus pneumoniae, Klebsiella pneumoniae and Escherichia coli. The phytochemical analysis was carried out using standard methods. The antibacterial activities of the aqueous, ethanol and acetone extracts of both plants at different concentrations were determined against all the test organisms using agar well diffusion method. All the extracts were found to contain important phytochemicals …

The Use Of Penalized Regression Analysis To Identify County-Level Demographic And Socioeconomic Variables Predictive Of Increased Covid-19 Cumulative Case Rates In The State Of Georgia, Holly L. Richmond, Joana Tome, Haresh Rochani, Isaac Chun-Hai Fung, Gulzar H. Shah, Jessica S. Schwind

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Systemic inequity concerning the social determinants of health has been known to affect morbidity and mortality for decades. Significant attention has focused on the individual-level demographic and co-morbid factors associated with rates and mortality of COVID-19. However, less attention has been given to the county-level social determinants of health that are the main drivers of health inequities. To identify the degree to which social determinants of health predict COVID-19 cumulative case rates at the county-level in Georgia, we performed a sequential, cross-sectional ecologic analysis using a diverse set of socioeconomic and demographic variables. Lasso regression was used to identify variables …

Global Research Output On ‘Coronavirus Disease-2019’ (Covid-19), Seema Parmar, Suman Ghalawat, Ashwani Kumar

Library Philosophy and Practice (e-journal)

Purpose: The present study reflects the trend and growth of publications on COVID-19 viral disease spreading around the world. With the emergence of COVID-19 in Wuhan, China in December 2019, scholars started publishing their researches in form of different kind of publications.

Methodology: The data has been extracted from the Scopus database using key TERMS Covid-19 and corona virus 2019.

Findings: During six month period around ten thousand publications are contributed by scientists around the globe. The literature produced in different fields but highest output is made in the field of Medicine. BMJ and Journal of Medical Virology journals …

Exploration Of Antiviral Effects Of Rna-Dependent Rna Polymerases 3, 4 And 5 In Arabidopsis., Eli R. Kallison, Aleksandra Beric, Blake Meyers

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

Small RNAs play a number of vital roles in plants, including viral resistance. A particular class of small RNA that regulates plant defense from pathogens, among other functions, is known as small interfering RNAs (siRNAs). A key player in the biogenesis pathway of siRNAs are RNA-Dependent RNA Polymerases (RDRs). There are six RDR proteins in Arabidopsis thaliana, three of which have well documented roles (RDRs 1, 2 and 6), and three of which have no documented role. Here, we look at the functions of the unstudied RDRs, RDRs 3, 4 and 5, to see whether they affect antiviral resistance.

A Case Of Plesiomonas Bacteremia Without Reported Freshwater Exposure, Abigail E. Mcdonald

HCA Healthcare Journal of Medicine

Introduction: Plesiomonas shigelloides is a member of the Enterobacteriaceae family generally found in freshwater. There is little substantive data about the prevalence or distribution of Plesiomonas within the United States. Plesiomonas are most commonly associated with mild, self-limited watery diarrhea among healthy individuals followed by infective colitis. Bacteremia is the most common extraintestinal manifestation of Plesiomonas. Few cases of Plesiomonas bacteremia can be found in the literature.

Clinical Findings: An elderly female with multiple comorbidities was admitted to our hospital for evaluation of generalized cramping abdominal pain of several days duration. She denied any freshwater or saltwater exposure. The …

International Conference On Pharmaceutical And Natural Sciences, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 9th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

Syndromic Surveillance Markers Associated With Dengue In Saint Lucia, Brendan Lee

Walden University Research Conference

This study was executed to identify the specific clinical symptoms associated with dengue in Saint Lucia. A retrospective, non-experimental study was designed using syndromic surveillance data from the Ministry of Health and Wellness Saint Lucia from 2009-2017. Results allowed the demonstration of a significant relationship between undifferentiated fever, acute respiratory infections or fever with respiratory signs, gastroenteritis, and dengue. These results potentially can be used by clinicians in Saint Lucia to more quickly identify cases of dengue that may have otherwise not have included dengue in an initial differential diagnoses list, especially in light of a current regional dengue epidemic. …

Scent-Based Rapid Screening, Anonymous

Defensive Publications Series

Many businesses engage in temperature monitoring, e.g., by the use of handheld IR thermometers or IR cameras, to ensure that a visitor to the business is not running a temperature which is a sign of the visitor being a potential carrier of an infectious disease such as COVID-19. However, such detection methods are imprecise and not particularly effective if the visitor is an asymptomatic person. This disclosure describes the use of scented strips to determine if a visitor may be infected. Visitors are requested to identify the smell of a strip dispensed by an automated dispenser machine or by a …

Surveillance Of Multidrug-Resistant Uropathogenic Escherichia Coli In Hospitalized Patients And Community Settings In The South Of Lebanon, Nourhan Darwich, Ali Samaha, Hanan Al Nuqaidan, Ahmad Tassi, Mirna Fawaz

BAU Journal - Health and Wellbeing

Urinary Tract Infection (UTI) is one of the common infectious diseases in both hospitals as well as community settings; they are recognized to be among the most serious worldwide bacterial infections impacting 150 million people globally every year. The purpose of this study was to assess the changing antibiotics resistance profile for uropathogenic Escherichia coli isolated from community and hospital setting over a period of time (2018–2019) with a special emphasis on ESBL/MDR producing Escherichia coli. A descriptive retrospective study was conducted among patients with uropathogenic Escherichia coli from both community and hospital settings in south Lebanon. Out of 863 …

Nutrition, Exercise, And Mental Health, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Understand factors that can impact our mental health

Understand how certain foods can benefit our mental health

Understand how exercise can benefit our mental health

2020-10-30_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Flu And Covid-19: How To Tell The Difference This Winter And Stay Safe, Alicia Rohan

Browse All News

No abstract provided.

The Inclusion Of Health Data Standards In The Implementation Of Pharmacogenomics Systems: A Scoping Review, Don Roosan, Angela Hwang, Anandi V. Law, Jay Chok, Moom Roosan

Pharmacy Faculty Articles and Research

Background: Despite potential benefits, the practice of incorporating pharmacogenomics (PGx) results in clinical decisions has yet to diffusewidely. In this study,we conducted a review of recent discussions on data standards and interoperability with a focus on sharing PGx test results among health systems. Materials & methods:We conducted a literature search for PGx clinical decision support systems between 1 January 2012 and 31 January 2020. Thirty-two out of 727 articles were included for the final review. Results: Nine of the 32 articles mentioned data standards and only four of the 32 articles provided solutions for the lack of …

Associations Of Dietary Diversity And Other Factors With Prevalence Of Stunting Among Children Aged 6-35 Months, Kelvin Halim, Ratu Ayu Dewi Sartika, Trini Sudiarti, Primasti Nuryandari Putri, Nurul Dina Rahmawati

Indonesian Journal of Public Health Nutrition (IJPHN)

Prevalence of stunting among under five children in Indonesia is still considered as a public health problem. Dietary diversity, one of the important assessments in infant and child feeding practice, is one of important determinants of stunting. This study is aimed to examine associations between dietary diversity with other factors with prevalence of stunting in Babakan Madang District, Bogor Regency in 2019. A cross-sectional design study was performed in this study during April-June in 2019. A total of 149 children’s height aged 6- 35 months was measured and defined based on WHO growth standards. Dietary diversity scores were collected from …

Selected Factors Related To Antibiotic Use And Antibiotic Resistance In Dumaguete City, Esther Faith M. Padilla, Kathryn Isabel R. Sotto, Shaun Jeco T. Balisado, Renzo John Phillip O. Cabagay, Nicole Allyson Fry, Micah Marie Gazo, Heather Hillary P. Infante, Calyn Marian F. Macarubbo, Jasmine T. Redona, Katherine A. Tambunting, Jessilda D. Verano

International Nursing Research Congress (INRC)

Misuse of antibiotics has led bacteria to develop antibiotic resistance— a detrimental and rapidly-growing health concern worldwide. This study aimed to assess the knowledge and attitude regarding antibiotic use and antibiotic resistance among residents in Dumaguete City.

A Bibliometric Analysis Of Scientific Output On Covid-19 Pandemic Outbreak Using The Web Of Science (Wos) Database, Mohamed Idhris, Sivasankar Prabaharan, Manuelraj Peter, Arun Vijay Subbarayalu

Library Philosophy and Practice (e-journal)

The novel coronavirus disease 2019 (COVID-19) has affected almost all the countries globally, and it is considered a global pandemic. Hence, this study conducted a bibliometric analysis of scientific output on the COVID-19 pandemic outbreak using the Web of Science (WoS) database. A specific search technique was developed based on Corona virus-related keywords from January 1, 2019, until June 24, 2020. A total of 10850 documents related to COVID-19 published from January 1, 2019, to June 24, 2020, were retrieved from the WoS database. The researchers downloaded the data from WoS as a WoS plain text file, and the data …

Pathway To Amplification In Children Who Passed Their Universal Newborn Hearing Screening Bilaterally, Derek J. Stiles, Kathryn Broughton, Jane Rose, Emily Trittschuh

Journal of Early Hearing Detection and Intervention

Purpose: The aim of this study was to investigate the pathway to amplification technologies for children who passed their universal newborn hearing screening (UNHS) bilaterally with the intent of revealing effective strategies to identify children with acquired or progressive hearing losses. Additionally, the degrees, types, and causes of hearing loss, as well as the types of amplification used by the patients were investigated. Methodology: Medical records were reviewed for 102 children who passed their UNHS bilaterally and who are enrolled in the Boston Children’s Hospital Amplification or Cochlear Implant Programs. Of the 204 total ears, 177 ears were identified with …

South Dakota Parents’ Knowledge Of Congenital Cytomegalovirus, Its Long-Term Health Effects, And Methods For Minimizing Exposure, Felicia Reimann, Jessica Messersmith, Hannah Williams, Emily Riley

Journal of Early Hearing Detection and Intervention

Congenital CMV (cCMV) is acknowledged as one of the most common causes of nonhereditary sensorineural hearing loss and an important cause of neurodevelopmental delay in children. Despite the danger cCMV poses, many parents are unaware of the virus, its sequelae, mode of transmission, and preventative behaviors. The purpose of the study was to determine South Dakota parents’ knowledge of cCMV, its sequelae, and ways to minimize exposure.

An electronic survey was utilized for data collection. Parents of children born in South Dakota from 2011 to 2018 were asked about their knowledge of CMV and cCMV, including common sequelae and ways …

Journal Of Early Hearing Detection And Intervention: Volume 5 Issue 2, Pages 1-84

Journal of Early Hearing Detection and Intervention

No abstract provided.

October 29, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …