Digital Commons Network^™

Physician Assistant Orlando 2017, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Semantic Inference On Clinical Documents: Combining Machine Learning Algorithms With An Inference Engine For Effective Clinical Diagnosis And Treatment, Shuo Yang, Ran Wei, Jingzhi Guo, Lida Xu

Information Technology & Decision Sciences Faculty Publications

Clinical practice calls for reliable diagnosis and optimized treatment. However, human errors in health care remain a severe issue even in industrialized countries. The application of clinical decision support systems (CDSS) casts light on this problem. However, given the great improvement in CDSS over the past several years, challenges to their wide-scale application are still present, including: 1) decision making of CDSS is complicated by the complexity of the data regarding human physiology and pathology, which could render the whole process more time-consuming by loading big data related to patients; and 2) information incompatibility among different health information systems (HIS) …

An Exploration Of Job Satisfaction Levels, Pathways Into Education, And Recruiting Behaviors Of Teachers In Indiana, Tricia Johnson

All-Inclusive List of Electronic Theses and Dissertations

Teacher retention and recruitment has been studied from many different perspectives, but there is limited research on the issue from the perspectives of current teachers. The purpose of this quantitative study was to gather data to fill a gap in the research concerning teacher recruiting behaviors by asking teachers if they were likely to encourage different categories of people (friend or relative, community member, current student, other students, recent high school graduate, and their own child) to enter the field of Education as a profession. Analysis of the data from 2,083 current Indiana teachers found multiple statistically significant differences in …

Uab Magazine - Fall 2017, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

Gonzaga University Factbook 2017-18, Institutional Research, Gonzaga University

Institutional Research

The Gonzaga University Factbook contains information on student enrollments, demographic profiles, admissions statistics, majors, retention and graduation rates, degree completions, faculty information, and more. It is updated annually with the most current and commonly-needed information about Gonzaga University.

A New Model For Phd Elective Course, H R. Ahmad, Satwat Hashmi, M H. Mahmood

Department of Biological & Biomedical Sciences

No abstract provided.

Eastern Magazine, Fall 2017, Eastern Michigan University

Alumni News: Eastern Magazine

No abstract provided.

A Comprehensive Molecular Phylogeny Of Holocephalans And Identification Of Sex-Specific Genetic Markers In Chondrichthyan Fishes, Jenny Marie Kemper

MUSC Theses and Dissertations

Holocephalan fishes occupy an important phylogenetic position as members of the basal clade of jawed vertebrates, as well as the sister group to bony vertebrates. Thus, they can be used to provide an important reference for comparative studies aimed at understanding early gnathostome genome evolution. However, despite this importance, holocephalans have been understudied, and no comprehensive phylogeny for their inter-relationships has been estimated. A phylogeny will provide information about ancestor-descendant relationships, forming a framework that can be used to test future hypotheses by mapping characters, identifying patterns, and estimating ancestral states. A cross-species hybridization capture method was used to sequence …

Low Cost, Multi-Purpose Genotyping Panels For Dairy And Beef Cattle, Michelle Judge

Theses

rhe selection of animals based on DNA has revolutionised animal breeding, but the associated high cost of obtaining genotypes has limited its uptake. The objective of this thesis was to develop a low-cost, low-density, multi-purpose genotyping panel for the procurement of reliable genotype information, and to quantify the long-term consequences of using such low-density genotype panels in breeding programs. The objectives were achieved through a combination of real-life cattle genotype data and simulations to mimic a cattle population. The in-silico development of genotype panels was based on actual genotypes from up to 58,705 beef cattle. Alternative novel strategies were used …

Development & Validation Of An Improved Biomechanical Model For Motion Analysis, Darren Dawson

Theses

Three dimensional motion analysis systems are utilised across a number of different disciplines, including clinical gait analysis, sports performance studies and analysis of tasks of daily living. These systems utilise biomechanical models which define body segment coordinate systems and calculate kinematic and kinetic relationships about the joints between adjacent coordinate systems. In this study, a biomechanical model for general use in motion analysis was developed and validated. It was designed to improve upon the accuracy and capability of currently available models. The newly developed model utilises state of the art techniques to accurately define body segment coordinate systems. Accurate predictive …

Fundamental Principles Of Tremor Propagation In The Upper Limb, Andrew D. Davidson, Steven Knight Charles

Faculty Publications

Although tremor is the most common movement disorder, there exist few effective tremor-suppressing devices, in part because the characteristics of tremor throughout the upper limb are unknown. To clarify, optimally suppressing tremor requires a knowledge of the mechanical origin, propagation, and distribution of tremor throughout the upper limb. Here we present the first systematic investigation of how tremor propagates between the shoulder, elbow, forearm, and wrist. We simulated tremor propagation using a linear, time-invariant, lumped-parameter model relating joint torques and the resulting joint displacements. The model focused on the seven main degrees of freedom from the shoulder to the wrist …

A Mathematical Investigation On Tumor-Immune Dynamics: The Impact Of Vaccines On The Immune Response, Jonathan Quinonez, Neethi Dasu, Mahboob Qureshi

College of Osteopathic Medicine (TUN) Publications and Research

Mathematical models analyzing tumor-immune interactions provide a framework by which to address specific scenarios in regard to tumor-immune dynamics. Important aspects of tumor-immune surveillance to consider is the elimination of tumor cells from a host’s cell-mediated immunity as well as the implications of vaccines derived from synthetic antigen. In present studies, our mathematical model examined the role of synthetic antigen to the strength of the immune system. The constructed model takes into account accepted knowledge of immune function as well as prior work done by de Pillis et al. All equations describing tumor-immune growth, antigen presentation, immune response, and interaction …

Using The Medication Cabinet To Predict Fall Risk In Elderly Adults, Jessica Lopez

University of the Pacific Theses and Dissertations

Background: In the United States, 30-60% of older adults fall each year; 10-20% of these falls result in injury, hospitalization, or even death. Better prevention of falls in this population may be facilitated by broader identification of risk factors. The use of statins has emerged as a potential risk factor, but the data provide conflicted results.

Purpose: To examine the relationship between statin use and falls among community-dwelling older adults.

Methods: We evaluated the patient registry of a Level 1 trauma center. All patients aged > 50 years who were admitted for falls in 2015 were included (n=615). Many of these …

Short-Wavelength Light-Blocking Eyeglasses Attenuate Symptoms Of Eye Fatigue, Carl Bassi, Jonathan Lin, Blair Gerratt, Rajendra Apte

College of Optometry Faculty Works

Purpose: The purpose of this study was to determine whether subjects who wear short wavelength–blocking eyeglasses during computer tasks exhibit less visual fatigue and report fewer symptoms of visual discomfort than subjects wearing eyeglasses with clear lenses.Methods: A total of 36 healthy subjects (20 male; 16 female) was randomized to wearing no-block, low-blocking, or high-blocking eyeglasses while performing a 2-hour computer task. A masked grader measured critical flicker fusion frequency (CFF) as a metric of eye fatigue and evaluated symptoms of eye strain with a 15-item questionnaire before and after computer use.Results: We found that the change in CFF after …

The Role Of N-Myc Downstream Regulated Gene 1 In Breast Cancer Lipid Metabolism, Christopher James Sevinsky

Legacy Theses & Dissertations (2009 - 2024)

Altered carbohydrate and lipid metabolism are increasingly well characterized hallmarks of aggressive breast cancers. While aerobic glycolysis, or “the Warburg effect”, is a well-established metabolic adaptation exploited by tumor cells, the understanding of unique aspects of cancer lipid metabolism lags behind. This is especially true regarding the coordination of complex lipid synthesis and trafficking pathways, which remains poorly understood. N-Myc Downstream Regulated Gene1 (NDRG1) is overexpressed in many solid tumors, but its function is unclear. The importance of NDRG1 is best exemplified by the effect of null mutations on human physiology: inactivating mutations give rise to the severe autosomal recessive …

Lived Experiences Of African American Males With Fibromyalgia, Ethel Denise Perry

Walden Dissertations and Doctoral Studies

Fibromyalgia (FM) is a musculoskeletal and neurological disorder that causes constant pain, cognitive problems with short term memory, and sleep disorders. There are more females diagnosed with FM than males, and research has therefore primarily been conducted with females. Because little is known about African American males with FM, biopsychosocial theory was used in this phenomenological study to examine how African American males with FM are affected biologically, psychologically, and socially. Eight African American males diagnosed with FM were recruited from Houston, Texas and were interviewed about their lived experiences with FM, including experiences with the healthcare system, and how …

Single Low-Dose Lipopolysaccharide Preconditioning: Neuroprotective Against Axonal Injury And Modulates Glial Cells, Ryan C. Turner, Zachary J. Naser, Brandon P. Lucke-Wold, Aric F. Logsdon, Reyna L. Vangilder, Rae Reiko Matsumoto, Jason D. Huber

Faculty Publications & Research of the TUC College of Pharmacy

AIM: Over 7 million traumatic brain injuries (TBI) are reported each year in the United States. However, treatments and neuroprotection following TBI are limited because secondary injury cascades are poorly understood. Lipopolysaccharide (LPS) administration before controlled cortical impact can contribute to neuroprotection. However, the underlying mechanisms and whether LPS preconditioning confers neuroprotection against closed-head injuries remains unclear.

METHODS: The authors hypothesized that preconditioning with a low dose of LPS (0.2 mg/kg) would regulate glial reactivity and protect against diffuse axonal injury induced by weight drop. LPS was administered 7 days prior to TBI. LPS administration reduced locomotion, which recovered completely …

Planaria: An Animal Model That Integrates Development, Regeneration And Pharmacology, Oné R. Pagán

Biology Faculty Publications

Although planarians are established model organisms in developmental biology and regeneration studies, in the last forty years or so, they have caught the attention of pharmacologists, especially to study the pharmacology of drugs of abuse. This review covers the following topics: some fundamentals of the history of animal models and planarians in biomedical research; an abbreviated story of systematic pharmacology research using planarians as a model organism; an example of how planarians are contributing to the search for compounds against acute cocaine toxicity; an analysis of the number of papers on planarians and pharmacological topics from 1900- 2016; some perspectives …

Open Educational Resource 2017 Textbook List, Zachariah Claybaugh, Chelsea Stone

Librarian Publications

This is an updated, discipline specific OER textbook list for departments at Sacred Heart University, compiled by Zach Claybaugh and Chelsea Stone.

Kss 5260 : Cardiopulmonary Exercise Physiology, Kinesiology & Sports Studies

Approved Course Proposals

No abstract provided.

Kss 4340 : Exercise Physiology, Kinesiology & Sports Studies

Approved Course Proposals

No abstract provided.

Altitude- And Sex-Specific Variation In Roosting Ecology And Thermoregulation Of Myotis Lucifugus In Yellowstone National Park, Alexandra C. Slusher

Theses and Dissertations--Forestry and Natural Resources

Fifty-nine female and six male little brown myotis (Myotis lucifugus) were radio-tagged during the summers of 2012, 2013, 2014, and 2015 in Yellowstone National Park. The grand models for daily maximum skin temperature (F_98,154 = 1.55, P = 0.007), daily minimum skin temperature (F_98,154 = 1.33, P = 0.05), and daily variation in skin temperature (F_98,154 = 1.56, P = 0.006) were significant across roost type and reproductive condition class for adult females. Roosts were classified into Types A (warmest roosts), B (roosts with largest daily temperature variance), and C (stable and cool roosts) depending …

Structural Characteristics And Corrosion Behavior Of Bio-Degradable Zn-Li Alloys In Stent Application, Shan Zhao

Dissertations, Master's Theses and Master's Reports

Zinc has begun to be studied as a bio-degradable material in recent years due to its excellent corrosion rate and optimal biocompatibility. Unfortunately, pure Zn’s intrinsic ultimate tensile strength (UTS; below 120 MPa) is lower than the benchmark (about 300 MPa) for cardiovascular stent materials, raising concerns about sufficient strength to support the blood vessel. Thus, modifying pure Zn to improve its mechanical properties is an important research topic.

In this dissertation project, a new Zn-Li alloy has been developed to retain the outstanding corrosion behavior from Zn while improving the mechanical characteristics and uniform biodegradation once it is implanted …

The Effects Of Aerobic Exercise And Lipolytic Stimulation On Skeletal Muscle And Adipose Expression Of Perilipin 3 (Plin3) In Individuals With Type 2 Diabetes And Women With Polycystic Ovary Syndrome, Jeffrey Daniel Covington

LSU Doctoral Dissertations

Ectopic lipid accumulation in skeletal muscle is linked with insulin resistance and type 2 diabetes (T2D). Neutral lipid is stored as lipid droplets, which are coated by lipid droplet coat proteins. One important class of these proteins are the perilipins. Little research has focused on perilipin 3 (PLIN3) and coatomer gtp-ases, theorized to be involved in PLIN3 directed lipid oxidation. Under lipolytic stimulation with epinephrine or palmitate, forskolin, and ionomysin (PFI), primary human myotubes taken from health non-T2D donors showed increased protein content levels of PLIN3. Concordantly, following endurance exercise in non-T2D males—an experimental paradigm shown to increase lipolysis—levels of …

How Can The Use Of Human Enhancement (He) Technologies In The Military Be Ethically Assessed?, Philip Andrew Taraska

Electronic Theses and Dissertations

War is a terrible price to pay for the prospect of peace. Yet every nation has a moral obligation to protect its citizenry from unjust aggression and threats to security. To be sure, war is always a failure. It is a failure of mankind to come together in mutual respect for the inherent dignity of the human person. The issue of the use of HE in the military is relevant today because the Global War on Terror (GWOT) and the rapid rise of emerging technologies have led to a never-before-seen type of asymmetrical warfare. The rise of these technologies can …

Unsung, Unprecedented, Unwavering: 2016-17 Report Of The President, Office Of The President, Gonzaga University

Office of the President Publications

Each year, Gonzaga University's Office of the President produces an annual Report of the President. This publication that highlights just a few of the many accomplishments over the previous academic year, and is intended to convey gratitude to our Trustees and Regents, benefactors, and many supporters.

Synthesis And Biological Evaluation Of Cannabinoid Receptor Ligands, Mariah Leigh Cole

Honors Theses

The cannabinoid receptors, members of the G-protein coupled receptor (GPCR) superfamily, have been implicated in numerous human physiological functions and diseases. These receptors, cannabinoid type 1 (CB1) and cannabinoid type 2 (CB2), are most concentrated in the central nervous system and immune cells, respectively, and have each become a target of therapeutic interest. Dual CB1/CB2 agonists such as delta-9-tetrahydrocannbinol (THC) have demonstrated efficacy in the treatment of nausea, pain, and glaucoma, but suffer from psychotropic effects mediated by CB1, motivating the search for CB2 selective therapeutic agents. Selective modulation of the CB2 receptor has therapeutic potential in human health disorders …

Chronicle & Character, Taryn Moller Nicoll

LSU Master's Theses

In this thesis paper, I argue that the works in the exhibition 'Chronicle & Character' aim to demonstrate artistic citizenship and can contribute positively to society by provoking conversation about universally applicable (but often uncomfortable) topics. Experts such as David J. Elliot state that being an artistic citizen means that one’s concerns as an artist must shift from issues constrained to the artist alone to those of the artist’s surrounding community. The exhibition 'Chronicle & Character' contains works that serve as detailed chronicles of the medical or physiological experiences of my loved ones. This body of work presents how three …

Examining The Hormonal Pleiotropy Hypothesis: Malayization Along An Elevational Gradient Can Be Associated With Behavioral, Hormonal And Immunological Differences In Lizards, Ryan Seddon

All-Inclusive List of Electronic Theses and Dissertations

Hormonal pleiotropy describes a suite of hormonally-linked traits. Such hormonal mediation may facilitate or constrain adaptive evolution of individual traits in the suite. Melanization, regulated in part by hormonal signals, can be tightly linked to non-color traits such as aggression, hormones, and immunity. While most studies examine within-population variation, I studied correlates of melanization, comparing both between- and within-population differences of adult male western fence lizards, Sceloporus occidentalis . I compared multiple high- and low-elevation populations in California, where populations are increasingly darker at higher elevations. I examined variation in 1) agonistic behavior of male lizards in response to staged …

Valveless Pumping: The Reflected Pulse Wave Hypothesis, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

No abstract provided.