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Articles 8521 - 8550 of 1791722
Full-Text Articles in Entire DC Network
Spirals Of Light: A Healing Journey Through Somatics, Dance, And Pedagogy, Jessica Batha
Spirals Of Light: A Healing Journey Through Somatics, Dance, And Pedagogy, Jessica Batha
MFA in Dance Theses
This thesis investigates dance as an embodied practice of healing, attunement, and belonging through phenomenology, somatics, and environmental engagement. Grounded in Sondra Fraleigh’s eco-phenomenological framework, the research weaves personal narrative, artistic inquiry, and interdisciplinary scholarship to examine how thresholds of birth, injury, and recovery shape sensory orientation across the lifespan. Drawing from lived experiences as a dancer, mother, educator, and researcher, the study explores tone, breath, light, and movement as formative forces in identity and resilience. Central to the inquiry is a knee injury and subsequent surgical recovery, which catalyzed a somatic practice aligned with circadian rhythms, sunrise ritual, and …
Kinesthesis: A Choreographic Study Of The Somatic Effect Of Fascial Intervention, Mira Larsen
Kinesthesis: A Choreographic Study Of The Somatic Effect Of Fascial Intervention, Mira Larsen
MFA in Dance Theses
This master’s thesis was a choreographic study that experimented with the somatic effects of fascial intervention practices, culminating in a final performance in June of 2026 at the LeFevre Theatre at Saint Mary’s College of California. Each chapter of this document investigates the topic of fascial awareness supported through somatic practice and its effect on creating impactful emotional and physical connections in ballet choreography and pedagogy. This document offers the conceptual framework for the choreographic process of the thesis project, titled Kinesthesis. Through the lenses of phenomenology, somatics, social justice, and performance studies, the research goal involved the utilization of …
“A Beautiful Mess: Rebirthing Through Earth, Dance, And The Divine”, Mikayla Douglas
“A Beautiful Mess: Rebirthing Through Earth, Dance, And The Divine”, Mikayla Douglas
MFA in Dance Theses
A Beautiful Mess: Rebirthing Through Earth, Dance, and the Divine by Mikayla Douglas is a culmination of research, creative practice, and lived experience that was developed during her time at Saint Mary’s College of California in the MFA Dance Program. This thesis investigates the shared dialogue between eco-somatics, eco-phenomenology, motherhood, nature, and the BIPOC birthing body. Through the use of outdoor somatic practices, personal reflection and stories, Mikayla Douglas explores how nature can serve as a site of healing, embodiment, and reclamation for Black and Brown birthing bodies. The research of this thesis work is grounded heavily in both scholarly …
Under Open Skies: Black, Queer, And Ascending, Skyler Zakaar
Under Open Skies: Black, Queer, And Ascending, Skyler Zakaar
MFA in Dance Theses
This thesis explores personal healing and community building through dance, rooted in my lived experience as a Black Queer man in America. Stemming from research in Phenomenology, Critical Dance Pedagogy, and Dance & Social Justice, I interrogate the impact of white supremacy and systemic racism both within and beyond the queer community. My choreographic process centers intersectionality and collective agency, seeking to resist the fragmentation of identity and to affirm the wholeness of self. Through performance and comprehensive study, my intentions are to foster empathy, connection, and belonging, while advocating for equity and transformation within dance and broader cultural discourse. …
State Policy And Regulatory Approaches To Sustainable Aviation Fuel Across The United States, Somtochukwu Attamah, Mary Johnson, Lara Fowler, Michael D. Helbing
State Policy And Regulatory Approaches To Sustainable Aviation Fuel Across The United States, Somtochukwu Attamah, Mary Johnson, Lara Fowler, Michael D. Helbing
Faculty Scholarship
Sustainable Aviation Fuel (SAF) represents a critical lever for achieving near-term decarbonization of the aviation industry. SAF can be manufactured for “drop-in” use in existing aircraft and fueling systems, allowing manufacturers to achieve lifecycle greenhouse gas (GHG) savings relative to standard jet fuel. However, U.S. policy is still disjointed: federal incentives are accompanied by diffuse state efforts, which means uneven market-based feedback and investment risk. After outlining the federal policy context, this Article conducts a comparative analysis of SAF-related policy frameworks across the fifty states. This includes a variety of government solutions offered in the form of enacted and proposed …
Why Pronatalism Fails The Planetary Health Test, Celine Delacroix, Marleen Temmerman, Nandita Bajaj, Ann Moore, Phoebe Barnard, William Ripple, William Rees, Michael Gerrard, Diana Coole, Robert Engelman
Why Pronatalism Fails The Planetary Health Test, Celine Delacroix, Marleen Temmerman, Nandita Bajaj, Ann Moore, Phoebe Barnard, William Ripple, William Rees, Michael Gerrard, Diana Coole, Robert Engelman
Centre of Excellence in Women and Child Health
No abstract provided.
Performance Of Road-Traffic-Based Exposure Proxies Against Personal Pm2.5 Measurements In Three Sub-Saharan African Countries, Handsome Nyoni, Terence Mushore, Laura Munthali, Sibusisiwe Makhanya, Laurine Chikoko, Stanley Luchters, Matthew Chersich, Fortunate Machingura, Liberty Makacha, Benjamin Barratt
Performance Of Road-Traffic-Based Exposure Proxies Against Personal Pm2.5 Measurements In Three Sub-Saharan African Countries, Handsome Nyoni, Terence Mushore, Laura Munthali, Sibusisiwe Makhanya, Laurine Chikoko, Stanley Luchters, Matthew Chersich, Fortunate Machingura, Liberty Makacha, Benjamin Barratt
Centre of Excellence in Women and Child Health
Particulate Matter (PM2.5) exposure contributes to the global disease burden, yet its monitoring remains sparse and uneven, with limited ground sensor infrastructure. Road-traffic proxy indicators can provide indirect estimates of PM2.5 where measurements are limited but require context-specific validation. We evaluated three PM2.5 road-traffic-related proxies: (i) population-Weighted Road Network Density (wRND), (ii) Euclidean (straight line) distance from highways (EH), and (iii) Euclidean distance from main roads (EM). We validated these proxies using high-resolution outdoor filtered PM2.5 personal exposure measurements collected over 1 year from 343 postpartum participants in The Gambia, Kenya, and Mozambique. Proxy-PM2.5 associations were assessed using Spearman correlation, …
Multi-Ancestry Polygenic Risk Scores For The Prediction Of Type 2 Diabetes And Complications In Diverse Ancestries, Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E. Petty, Hong Kiat Ng, Jaewon Choi, Simon Lee, John Blangero
Multi-Ancestry Polygenic Risk Scores For The Prediction Of Type 2 Diabetes And Complications In Diverse Ancestries, Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E. Petty, Hong Kiat Ng, Jaewon Choi, Simon Lee, John Blangero
Human Genetics Publications
Background: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global clinical utility. We aimed to deliver comprehensive and rigorously tested multi-ancestry PRSs for prediction in type 2 diabetes.
Methods: We conducted meta-analyses using data from type 2 diabetes genome-wide association studies (GWAS) across cohorts from five major global ancestries: European, African or African American, Admixed American, South Asian, and East Asian. We used summary statistics from the GWAS to construct single-ancestry PRSs (using the continuous-shrinkage PRS-CS …
Neonatal Admissions And Mortality: A Statistical Adjustment Approach Using Birthweight-Specific Curves To Address Bias Due To Underreporting In 65 Hospitals In Four African Countries, Lucas Malla, Siu Wong, Samuel Ngwala, Evelyn Zimba, Msandeni Chiume, Norman Lufesi, Kondwani Kawaza, Honorati Masanja, Josephine Shabani, William Macharia
Neonatal Admissions And Mortality: A Statistical Adjustment Approach Using Birthweight-Specific Curves To Address Bias Due To Underreporting In 65 Hospitals In Four African Countries, Lucas Malla, Siu Wong, Samuel Ngwala, Evelyn Zimba, Msandeni Chiume, Norman Lufesi, Kondwani Kawaza, Honorati Masanja, Josephine Shabani, William Macharia
Paediatrics and Child Health, East Africa
Background Underreporting of neonatal admissions and deaths – particularly among < 1000 g newborns – compromises the plausibility of in-patient neonatal mortality rate (iNMR) estimates. This limits progress tracking, since 2.3 million neonatal deaths occur annually, and 65 countries are projected to miss the Sustainable Development Goal (SDG) 3.2 target of fewer than 12 deaths per 1000 live births by 2030. Reliable iNMR estimates are essential for national and hospital-level monitoring. This study assessed birthweight-specific adjustment curves developed using simulated data, and extended the approach to routine data from 172,809 neonatal admissions across four African countries in the NEST360 network.
Methods Simulated data were generated using birthweight intervals of 500 g from 500 to 5000 g, with 1000 values per category representing 1000 hospitals. Admissions were drawn from a negative binomial distribution and mortality rates from a beta distribution based on published birthweight-specific iNMRs. Adjustment functions were developed using data from 500 hospitals without underreporting and tested on 500 with induced underreporting. This approach was then extended to real data from 65 NEST360 partnering hospitals. The adjustment functions were derived from 26 hospitals with plausible reporting (iNMR ≥ 700 per …
Unlocking The Potential Of Sub-Saharan Africa In Globalized Cancer Clinical Trials: A Perspective From The 2024 Aortic-Asco Stakeholder Meeting, Abiola Ibraheem, Adedayo Joseph, Miriam Mutebi, Mansoor Saleh, Sitna Mwanzi, Olusegun Alatise
Unlocking The Potential Of Sub-Saharan Africa In Globalized Cancer Clinical Trials: A Perspective From The 2024 Aortic-Asco Stakeholder Meeting, Abiola Ibraheem, Adedayo Joseph, Miriam Mutebi, Mansoor Saleh, Sitna Mwanzi, Olusegun Alatise
General Surgery, East Africa
Sub-Saharan Africa (SSA) remains significantly underrepresented in global cancer clinical trials, despite having the largest population of individuals of African descent, an essential demographic for ensuring diversity in clinical research. This study, developed from the 2024 African Organization for Research and Training in Cancer (AORTIC)-ASCO stakeholder meeting, addresses the critical need to involve SSA in cancer trials to improve global trial diversity and patient outcomes. Although globalization of trials has shifted research sites to regions like Eastern Europe and Asia, < 1% occur in Africa. This report highlights emerging solutions such as regional alliances, decentralized trial models, capacity-building initiatives, and public-private partnerships. The role of AORTIC and its Clinical Trial Special Interest Group in advancing training, infrastructure development, and international collaboration is discussed, with notable clinical trial networks, such as HypoAfrica, ARETTA, African Research Group for Oncology, and regional consortia, illustrating growing momentum and capability. This study advocates for a coordinated strategy to integrate SSA into global trials, ensuring more inclusive, effective, and equitable cancer treatment outcomes.
Valorisation Potential Of Microalgae As A Sustainable Source Of Lipids And Health Promoting Compounds, Bozena Mccarthy
Valorisation Potential Of Microalgae As A Sustainable Source Of Lipids And Health Promoting Compounds, Bozena Mccarthy
Theses
The transition toward a circular bioeconomy requires sustainable strategies for managing and valorising food industry effluents while reducing reliance on environmentally damaging raw materials such as palm oil, which is associated with deforestation, biodiversity loss and greenhouse gas (GHGs) emissions. Microalgae represent a promising platform for converting nutrient rich industrial by-products into biomass and high-value compounds for food, nutraceutical and bio-based applications. Dairy processing generates large quantities of whey, creating environmental challenges due to its high organic load. Improved whey treatment and valorisation strategies are therefore essential for enhancing sustainability in food production systems. In this study, the biomass productivity …
Pyogenic Liver Abscess Associated With Acute Hepatitis A And Burkholderia Cepacia Sepsis In A Child: A Rare Case Report, Anjali M, Poonam Wade, Snehal Sahebrao Kasbe, Neha Bhongale
Pyogenic Liver Abscess Associated With Acute Hepatitis A And Burkholderia Cepacia Sepsis In A Child: A Rare Case Report, Anjali M, Poonam Wade, Snehal Sahebrao Kasbe, Neha Bhongale
Digital Journal of Clinical Medicine
Pyogenic liver abscess is an uncommon but potentially life-threatening infection in children. Although it is usually associated with underlying predisposing conditions, its occurrence in association with acute hepatitis A is infrequently reported.
We report a case of a 4-year-old male child who presented with fever, jaundice, and abdominal distension and was diagnosed with pyogenic liver abscess associated with concurrent hepatitis A infection and Burkholderia cepacia complex sepsis.
This case underscores the need to consider secondary bacterial infection in children with hepatitis A who have persistent fever or an unexpected clinical course despite appropriate supportive care. Although jaundice may initially be …
Social Phobia, Coping Strategies, And Socio-Demographic Associations Among Late Adolescents: A Cross-Sectional Study, Ezhilan B U, Jesymol Joy, Smitha Chandrashekarappa Dr.
Social Phobia, Coping Strategies, And Socio-Demographic Associations Among Late Adolescents: A Cross-Sectional Study, Ezhilan B U, Jesymol Joy, Smitha Chandrashekarappa Dr.
Digital Journal of Clinical Medicine
Background: Adolescence is a transitional period from childhood to adulthood, often marked by psychological challenges such as social anxiety, also known as social phobia. It is characterized by excessive fear of social interactions and can lead to impaired functioning or depression. Globally, its prevalence ranges from 6-10% in developed countries and 10-44% in developing countries. Coping strategies play a crucial role in managing social phobia, varying by individual characteristics. This study aimed to determine the prevalence of social phobia, identify coping strategies, and evaluate their association with socio-demographic factors among late adolescents.
Methodology: A cross-sectional study was conducted …
Can The Epa Withdraw The Endangerment Finding?, Jonathan Adler
Can The Epa Withdraw The Endangerment Finding?, Jonathan Adler
Faculty Publications
The Trump administration has made repeal of the Environmental Protection Agency’s “endangerment finding” on greenhouse gases the centerpiece of its environmental deregulation agenda. “We are driving a dagger straight into the heart of the climate change religion to drive down cost of living for American families, unleash American energy, bring auto jobs back to the US, and more,” proclaimed EPA Administrator Lee Zeldin when announcing the agency’s plan to reconsider the finding in March 2025. Since then, the agency has followed through, pushing endangerment finding repeal ahead of other, more traditional, deregulatory efforts. While politically popular with parts of President …
An Abundant Lack Of Introspection, Jonathan Adler
An Abundant Lack Of Introspection, Jonathan Adler
Faculty Publications
In this review Jonathan Adler critiques Abundance authors Klein and Thompson's analysis of how regulation is holding back progress in decarbonization, America's housing supply crisis, and innovation. While agreeing with the authors' assessment that regulation policy is hampering efforts in these areas, Adler objects to the book's proposals for improving regulatory bottlenecks, arguing the authors of Abundance refuse to acknowledge the role of market institutions in creating abundant supply or to admit the fault in their assumption that the failures of centralized government decision making can be repaired while maintaining centralized government decision making.
This abstract has been constructed from …
Health Systems Interventions For Prevention Of Maternal Peripartum Infection In Low And Middle-Income Countries: A Systematic Review, Roseline Abwao, Job Mapesa, Wanja Tenambergen, David Odada, Nasra Gathoni, Felix Riunga
Health Systems Interventions For Prevention Of Maternal Peripartum Infection In Low And Middle-Income Countries: A Systematic Review, Roseline Abwao, Job Mapesa, Wanja Tenambergen, David Odada, Nasra Gathoni, Felix Riunga
Internal Medicine, East Africa
Background Globally, there is growing recognition that a functional health system is key to improving maternal health and reducing maternal mortality. Maternal peripartum infection remains a major cause of maternal morbidity and mortality, particularly in low- and middle-income countries. This infection is a multifaceted problem with many players. Adopting a health systems approach could help avert this preventable infection by addressing the gaps across all the components of care.
Objective The aim of this systematic review was to identify and evaluate interventions to prevent maternal peripartum infection in LMICs.
Methods A systematic search was conducted in Cochrane Library, CINAHL, MEDLINE …
The Privacy Trap: Keeping Sensitive Data Safe In The Ai Era, Xiaohui Liang
The Privacy Trap: Keeping Sensitive Data Safe In The Ai Era, Xiaohui Liang
Paul English Applied Artificial Intelligence (AI) Institute Publications
This presentation examines privacy and data security risks associated with the growing use of artificial intelligence, with particular attention to the sensitive information users may disclose when interacting with AI systems. It explores how voice, text, images, and prompts can expose personally identifiable and privacy-sensitive information and introduces privacy threats associated with large language models and other AI systems. The presentation discusses approaches for identifying and protecting sensitive information, including named entity recognition, prompt modification, masking, replacement, and other privacy-preserving techniques. It also examines the trade-off between protecting privacy and maintaining the usefulness of AI-generated responses. Drawing on research in …
Confidenceai: A Wearable And Predictive Ai Ecosystem, Denzil Paul, Xuejun Kong, Raymond Wang, Flora Fleith Lopes, Zhengjia Yang, Brain Chu, Weijian Wang, Leo Chen
Confidenceai: A Wearable And Predictive Ai Ecosystem, Denzil Paul, Xuejun Kong, Raymond Wang, Flora Fleith Lopes, Zhengjia Yang, Brain Chu, Weijian Wang, Leo Chen
Paul English Applied Artificial Intelligence (AI) Institute Publications
This group project presents ConfidenceAI, a conceptual wearable and predictive artificial intelligence ecosystem designed to help teenagers build confidence and manage stress in high-pressure situations such as classroom participation and public speaking. The system combines wrist-based biosensing with a personalized machine-learning model that uses physiological signals, including heart rate and heart rate variability, electrodermal activity, skin temperature, and movement, to learn an individual's baseline patterns and anticipate heightened stress responses. Rather than relying on universal thresholds, ConfidenceAI is designed to personalize the timing, method, and delivery of interventions based on each user's physiological patterns and prior responses. The proposed ecosystem …
The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 104, Issue 1, Summer 2026
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
This issue includes:
- 5 - Dean's Column
- 6 - Time Machine
- 8 - TJU News
- 12 - Discovery
- 14 - Remembering a Renaissance Man
- 20 - A Conversation with a Jefferson Legend
- 24 - 2026 Scholarship Celebration Recap
- 26 - Bridging Gaps - and Building Bridges
- 28 - Looking Out for the Next in Line
- 30 - Welcome SKMC Class of 2030
- 32 - Meet Our Alumni
- 34 - Class Ambassadors
- 36 - A Message From the SKMC Alumni Board President
- 38 - Class Notes
- 42 - In Memoriam
- 46 - By the Numbers
Southeastern Librarian 74(2) Summer 2026 (Full Issue)
Southeastern Librarian 74(2) Summer 2026 (Full Issue)
The Southeastern Librarian
Complete issue of the Southeastern Librarian, Volume 74 Number 2, Summer 2026
Second Acts In Academic Librarianship: Trends, Impacts, And Implications, Tiffany Davis Norris, Phill Johnson
Second Acts In Academic Librarianship: Trends, Impacts, And Implications, Tiffany Davis Norris, Phill Johnson
The Southeastern Librarian
This study investigates the increasingly common phenomenon of academic librarianship as a second career. Survey data from more than 500 academic librarians found that nearly 70 percent of respondents did not begin their professional lives in the library field. These findings challenge the long-held perception of librarianship as an early or primary career choice and highlight significant trends with implications for library education, recruitment, leadership development, and burnout prevention. The study explores patterns in first careers and examines demographic trends, age distributions, and correlations between career background and current leadership roles. By framing librarianship as a deliberate career pivot rather …
Christianity, Gender Identity, Parents’ Rights: Book Censorship Discourse In Tennessee Communities, Janet Kesterson Isbell, Shawn Hinkel
Christianity, Gender Identity, Parents’ Rights: Book Censorship Discourse In Tennessee Communities, Janet Kesterson Isbell, Shawn Hinkel
The Southeastern Librarian
Hate and hostility toward the lesbian, gay, bisexual, transgender, queer+ (LGBTQ+) community and people of color, inflamed in recent years by political extremism and radical conservatism, have permeated many areas of society. One context where hostilities have emerged in the past decade is public debate surrounding book challenges, which prompted a yearlong investigation into the polarizing phenomenon of book censorship in the United States. After extensive reading of media reports from around the nation, the authors focused on public discourse related to book challenges in Tennessee public and school libraries, where debate was contentious, librarians were threatened, and the state’s …
News From The States, A. Blake Denton
News From The States, A. Blake Denton
The Southeastern Librarian
Library news reports from SELA member states
Antibody-Oligonucleotide Conjugates: An Emerging Modality For Precision Rna Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, Kyoji Tsuchikama, Wenbo Li
Antibody-Oligonucleotide Conjugates: An Emerging Modality For Precision Rna Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, Kyoji Tsuchikama, Wenbo Li
The Brown Foundation: Institute of Molecular Medicine
RNA-targeting therapeutics have enormous potential to precisely target disease-causing RNAs, extending beyond the traditional limits of "druggability" for small molecules, antibodies, and protein-targeting cell therapies. However, one crucial limitation is that RNA-targeting drug modalities (such as oligonucleotides) cannot effectively reach diseased tissue or cell types. Antibody-oligonucleotide conjugates (AOCs) emerge as a promising frontier in aiding RNA therapeutics by harnessing antibodies to deliver drug modalities to target specific RNAs in desired tissues or cells. In this Review, we summarize the critical components of AOCs, key considerations for their design and manufacturing, ongoing AOCs in preclinical/clinical development, and disease indications. We discuss …
Nano-Bio Interfacial Effects Modulating Protein Adsorption In Dialdehyde Lentinan-Crosslinked Polysaccharide Sponges Reinforced With Zein Nanoflowers, Dorota Chelminiak-Dudkiewicz, Miloslav Machacek, Hana Janová, Klara Konecna, Ondrej Jandourek, Jana Kejmarová, Kinga Mylkie, Aleksander Smolarkiewicz-Wyczachowski, Marta Ziegler-Borowska
Nano-Bio Interfacial Effects Modulating Protein Adsorption In Dialdehyde Lentinan-Crosslinked Polysaccharide Sponges Reinforced With Zein Nanoflowers, Dorota Chelminiak-Dudkiewicz, Miloslav Machacek, Hana Janová, Klara Konecna, Ondrej Jandourek, Jana Kejmarová, Kinga Mylkie, Aleksander Smolarkiewicz-Wyczachowski, Marta Ziegler-Borowska
The Brown Foundation: Institute of Molecular Medicine
The interfacial organization of porous biomaterials critically influences protein adsorption and subsequent cell-material interactions at hydrated biointerfaces relevant to wound-contacting environments. Herein, hybrid sponges were developed by rationally assembling chitosan, lentinan, levan, and fucoidan into a covalently defined macromolecular network featuring nano-bio interfacial effects. The materials were designed to modulate interfacial biological performance via engineered pore-wall structures, with protein-layer formation at sponge interfaces associated with downstream cell-material responses. A dialdehyde lentinan was deliberately employed to establish a chemically defined pore-wall interface via dense Schiff-base junctions with chitosan. The incorporation of zein nanoflowers introduced additional nanoscale structure features, providing additional anchoring …
Cost Utility Analysis Of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation For Chronic Rhinosinusitis With Nasal Polyps, Daniel Xiao, Martin J Citardi, William C Yao, Amber U Luong
Cost Utility Analysis Of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation For Chronic Rhinosinusitis With Nasal Polyps, Daniel Xiao, Martin J Citardi, William C Yao, Amber U Luong
The Brown Foundation: Institute of Molecular Medicine
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is managed after sinus surgery with topical corticosteroids. Given limited distribution of nasal steroid sprays, patients have the option of either steroid nasal irrigation (SNI) or exhalation delivery system with fluticasone (EDS-FLU). This study evaluates the cost-effectiveness of EDS-FLU compared to SNI for CRSwNP.
Methods: A cohort-style Markov decision-tree economic model with a 33-year time horizon was developed in TreeAgePro. Because EDS-FLU is not currently covered by Medicare, costs of medications were estimated using retail pricing. A willingness-to-pay threshold of $50,000/quality adjusted life year (QALY) was used to determine cost-effectiveness. One-way and probabilistic …
Functional Characterization Of Uhrf1 Variants In Facilitating Dna Methylation, Bigang Liu, Kaila Nayvelt, Swanand Hardikar, Kimie Kondo, Marcos R Estecio, Xiaodong Cheng, Taiping Chen
Functional Characterization Of Uhrf1 Variants In Facilitating Dna Methylation, Bigang Liu, Kaila Nayvelt, Swanand Hardikar, Kimie Kondo, Marcos R Estecio, Xiaodong Cheng, Taiping Chen
The Brown Foundation: Institute of Molecular Medicine
Ubiquitin-like with plant homeodomain (PHD) and really interesting new gene (RING) finger domains 1 (UHRF1) is essential for DNA methylation inheritance. However, the functional impacts of several natural and engineered UHRF1 variants are either insufficiently characterized or obscured by conflicting results, with some discrepancies likely stemming from cellular toxicity and adaptive responses induced by DNA methylation changes. In this study, we utilized mouse embryonic stem cells (mESCs)-which uniquely tolerate the complete loss of DNA methylation-to evaluate the functional consequences of clinical mutations, isoform variation, and epitope tagging. Using rescue experiments in Uhrf1-deficient mESCs, we characterized two UHRF1 mutations identified in …
Da Mosang Tarsier Series: Developing Digital Bullying Prevention Materials For Filipino Parents Of Grade School Students, Rudy M. Danganan Jr., Ann Christine V. Braga, Maria Kristina S. Alfonso, Romelito Manuel D.S. Clorina, Ma. Regina Hechanova
Da Mosang Tarsier Series: Developing Digital Bullying Prevention Materials For Filipino Parents Of Grade School Students, Rudy M. Danganan Jr., Ann Christine V. Braga, Maria Kristina S. Alfonso, Romelito Manuel D.S. Clorina, Ma. Regina Hechanova
Children and Families
Bullying remains a significant public health and educational concern worldwide and is particularly prevalent in Philippine public schools, with Grade 7 students identified as a vulnerable group. Although the Anti-Bullying Act of 2013 (Republic Act No. 10627) mandates school-based policies and procedures, persistent implementation gaps underscore the need to strengthen home–school partnerships and equip parents with practical, culturally grounded response strategies. This paper describes the development of the Da Mosang Tarsier Series, a set of digital psychoeducational comic strips designed for Filipino parents of Grade 7 students. Guided by a user-centered design (UCD) framework, the project began with a Generative …
Medical, Socioeconomic, And Geographic Disparities In Primary Health Care Access And Utilization: A Population-Based Study Of 8038 Individuals Aged One Year And Older In Rural Uganda, Saadiyah Mayet, Christin Puthur, Betty Nabatte, Benjamin Tinkitina, Christopher Opio, Yin-Cong Zhi, Narcis Kabatereine, Goylette Chami
Medical, Socioeconomic, And Geographic Disparities In Primary Health Care Access And Utilization: A Population-Based Study Of 8038 Individuals Aged One Year And Older In Rural Uganda, Saadiyah Mayet, Christin Puthur, Betty Nabatte, Benjamin Tinkitina, Christopher Opio, Yin-Cong Zhi, Narcis Kabatereine, Goylette Chami
Internal Medicine, East Africa
Background There is limited data on trends in primary health care (PHC) access and utilisation in rural sub-Saharan Africa, with a particular lack of knowledge on disparities beyond geographic barriers.
Methods A cross-sectional study was conducted within the community-based cohort, SchistoTrack. 2191 households were randomly sampled from 52 rural villages in Pakwach, Buliisa, and Mayuge Districts in Uganda. All household members aged one year and older were surveyed between 2022–2024, resulting in 8038 individuals with baseline health access information. Key outcomes included any care sought within the month preceding the study, type of care sought, and usual source of care. …
Just Opt For Caesarean Section And Pick The Birthdate': A Qualitative Study Exploring Women's Delivery Preferences After Caesarean Section In Urban Tanzania, Daudi Gidion, Columba Mbekenga, Miriam Mgonja, Marleen Temmerman, Muzdalfat Abeid
Just Opt For Caesarean Section And Pick The Birthdate': A Qualitative Study Exploring Women's Delivery Preferences After Caesarean Section In Urban Tanzania, Daudi Gidion, Columba Mbekenga, Miriam Mgonja, Marleen Temmerman, Muzdalfat Abeid
Obstetrics and Gynaecology, East Africa
Objectives To explore perspectives, preferences and decision-making regarding mode of delivery after a previous caesarean section among women in urban Tanzania.
Design A descriptive qualitative study using semi-structured in-depth interviews. Data were analysed using thematic analysis.
Setting A private tertiary hospital in Dar es Salaam, Tanzania.
Participants 11 women with one previous caesarean section who delivered at the study site were interviewed on the third day after delivery. Participants were purposively sampled to include both modes of delivery: five women underwent repeat caesarean section and six attempted a trial of labour after caesarean (TOLAC).
Results Thematic analysis identified four key …