Digital Commons Network^™

Time Alters Distinct Memories Driven By Sensory Prediction Errors And Task Errors In Sensorimotor Adaptation, Li Ann Leow, Welber Marinovic, Scott Albert, Timothy J. Carroll

Research outputs 2022 to 2026

Prior learning can impair future learning when the requirements of the two memories conflict, a phenomenon termed anterograde interference. In sensorimotor adaptation, the passage of time between initial and future learning can reduce such interference effects, leading to the interpretation that time consolidates motor memories, protecting motor memories from interference. However, we still do not fully understand how time affects learning, as some studies found no effects of time on interference. One possible explanation for such inconclusive findings is that time has distinct effects on the multiple processes underpinning sensorimotor adaptation, and these processes may compensate for each other's effects …

Winds Of Change: Charting A Pathway To Ecosystem Monitoring Using Airborne Environmental Dna, Rachel L. Tulloch, Clare I.M. Adams, Matthew A. Barnes, Elizabeth L. Clare, Henrik C. Van De Ven, Andrew Cridge, Francisco Encinas-Viso, Kristen Fernandes, Dianne M. Gleeson, Erin Hill, Anna J.M. Hopkins, Anna M. Kearns, Gracie C. Kroos, Anna J. Macdonald, Francesco Martoni, Angela Mcgaughran, Todd G.B. Mclay, Linda E. Neaves, Paul Nevill, Andrew Pugh, Kye J. Robinson, Fabian Roger, Tracey V. Steinrucken, Mieke Van Der Heyde, Cecilia Villacorta-Rath, Jenny Vivian

Research outputs 2022 to 2026

Airborne environmental DNA (airborne eDNA) analysis leverages the globally ubiquitous medium of air to deliver broad species distribution data and support ecosystem monitoring across diverse environments. As this emerging technology matures, addressing critical challenges and seizing key opportunities will be essential to fully realize its potentially transformative impact. In June 2024, the Southern eDNA Society convened over 100 researchers, industry leaders, and biodiversity management stakeholders in a landmark workshop to evaluate the current state of airborne eDNA research and chart a course for future development. Participants explored opportunities for integrating airborne eDNA into existing monitoring systems, but they unanimously agreed …

Descending Asymmetry In Proximate, Mobile And Digital Care: Chinese Older People Grandparenting Across Distance Within China And Overseas, Catriona Stevens, Rachel Murphy, Yu Huang, Loretta Baldassar

Research outputs 2022 to 2026

This article juxtaposes cases of grandparents who provide care for their grandchildren in two broad types of migrant families: (1) families where some members have migrated from the Chinese countryside to larger cities and (2) families where some members have migrated from China to Australia. By examining the proximate, mobile and digital forms of their grandparenting care labour, this article demonstrates the surprising durability and stability of care repertoires across distance and class. Despite the great differences of their migration geographies and family resources, these families nonetheless all demonstrate remarkably similar repertoires of caregiving articulated with reference to similar cultural …

Psychological Distress Among Suicide Exposed And Subsequently Bereaved Carers, Myfanwy Maple, Navjot Bhullar, Marie Reid, Sarah Wayland

Research outputs 2022 to 2026

People bereaved by suicide are at risk of developing significant mental health issues, including the risk of self-harm. To understand suicide exposure and psychological factors contributing to these adverse outcomes, survey data from 92 participants (Meanage = 53.50 years, SD = 14.5, female = 83.7%) who had provided care to someone who subsequently died by suicide were used. Participants responded to questions relating to suicide exposure, bereavement, suicidal ideation and psychological distress. A hierarchical regression analysis found that the perceived impact of suicide death and one's own suicidal ideation explained 46% variance in psychological distress. Suicide bereaved carers are highly …

Climate Fiction Of The Anthropocene, Joseph Paul Ferguson, Cassandra Tytler, Peta J. White, Susan Oliver

Research outputs 2022 to 2026

No abstract provided.

Post-Anthropocene Provocations: Human-Sized Scholars’ Rocks, Cronenbergian Flesh Caves And Zen Garden Design Cues For A Future Proof Re(Image)Ining, Brenton Rossow, Darren Tynan

Research outputs 2022 to 2026

This research explores concertinaing past, present and future interventional creative and pedagogical practices to address the challenges of the Post-Anthropocene era. We argue that the Post-Anthropocene is marked by biotechnological entanglements, environmental violence and digital overstimulation. The discussions herein critique a hyperattentive achievement society characterised by a scattering of attention, a near-constant screen-mediated stream of digital material and tasks and the commodification of leisure time. Enlisting Byung-Chul Han’s concept of hyperattention and themes and motifs from David Cronenberg’s films, the authors propose “FUTURE PROOF re(image)ining” as a collaborative Cli-Fi narrative concept. The project reimagines objects from an initial art installation …

Double Trouble: A Rare Cause Of Bilateral Upper Extremity Swelling, Lauren Abbas, Sheena Mckenzie

Advocate GME

No abstract provided.

Blue In The Face: Unraveling A Hypoxic Mystery, Lauren Abbas, Sheena Mckenzie

Advocate GME

No abstract provided.

Breast Reconstruction In Becker Nevus Syndrome, Alexis K. Schlosser, Mohammed S. Rais, Ruston J. Sanchez

School of Medicine Faculty Publications

Becker nevus syndrome is a rare cutaneous disorder characterized by the presence of a hyperpigmented patch of skin typically occurring on the upper trunk, often associated with hypertrichosis, and sometimes associated with musculoskeletal abnormalities ipsilateral to the nevus. Becker nevus syndrome can lead to breast hypoplasia. Unlike other forms of breast hypoplasia, treatment should begin before the completion of breast development. Due to the rarity of the disease, breast reconstruction in these patients has no gold-standard approach, and treatment is often delayed. Therefore, our case report highlighted the need for early treatment and provided options for reconstruction in this population. …

The Mental Health Bill (2025) For England And Wales: Professional And Carer Consensus Statement Summarising Concerns And Unintended Consequences From Proposed Changes To Autism And Learning Disability, Rohit Shankar, Peter Beazley

Peninsula Medical School

The Mental Health Bill, 2025, proposes to remove autism and learning disability from the scope of Section 3 of the Mental Health Act, 1983 (MHA). The present article represents a professional and carer consensus statement that raises concerns and identifies probable unintended consequences if this proposal becomes law. Our concerns relate to the lack of clear mandate for such proposals, conceptual inconsistency when considering other conditions that might give rise to a need for detention and the inconsistency in applying such changes to Part II of the MHA but not Part III. If the proposed changes become law, we anticipate …

L-Quebrachitol Modulates The Anti-Convulsant Effects Of Carbamazepine Possibly Through Voltage-Gated Sodium Channel Blocking Mechanism In Chicks: In Vivo And In Silico Studies, Asifa Asrafi, Mohammad Aslam, Ali G. Alkhathami, Md. Sakib Hossain, Imam Hossen Rakib, Md. Sakib Al Hasan, Feroz Khan Nun, Md. Faisal Amin, Muhammad Torequl Islam

School of Integrative Biological & Chemical Sciences Faculty Publications

Introduction: L-Quebrachitol (LQB), a naturally occurring bioactive compound, exhibits anti-inflammatory, anti-oxidant, anti-cancer, and anti-diabetic properties. However, its therapeutic potential in convulsant management remains largely unexplored. The objective of this study was to investigate the anticonvulsant effects of LQB in an In Vivo model and to examine its molecular interactions via In Silico docking simulations.

Methods: In the In Vivo study, pentylenetetrazol (PTZ) was administered intraperitoneally (i.p.) at 80 mg/kg to induce convulsions, and the test animals were treated orally with three doses of LQB (1, 5, and 10 mg/kg), with carbamazepine (CBZ) at 80 mg/kg as a standard drug.

Results: …

Bibliometric Analysis Of Congenital Toxoplasmosis: A Ten-Year (2013-2023) Review Of Research Publications, Festus Mulakoli, Horatius Musembi, Ann Kimani

School of Nursing & Midwifery, East Africa

Background:Toxoplasma gondii, an obligate intracellular protozoan, infects more than one-third of the global population and causes toxoplasmosis, which can lead to severe fetal complications in pregnant women. The global prevalence of latent toxoplasmosis in pregnant women is 33.8%, with regional variations and risk factors, including the consumption of undercooked meat, exposure to cat feces, and consumption of contaminated water. Pregnant women lack sufficient awareness of these risk factors, necessitating enhanced education, regular screening, and counseling during antenatal care for early detection and management.

Aim: This study performed a comprehensive bibliometric analysis of research on congenital toxoplasmosis published between 2013 …

A Wearable-Based Approach To Spinal Posture Tracking And Assessment, Sydney Marie Sherman, Noah Jeffery

Biomedical Engineering: Graduate Reports and Projects

This paper describes the design, manufacturing, and testing of a novel spinal posture tracking wearable device with embedded sensors. Currently on the market, most of the spinal posture tracking devices only focus on one segment of the spine and therefore do not track the entirety of human posture. The objective for this project was to create a wearable device in the form of a “smart shirt” that offers insights into posture trends throughout the day by tracking the entire spine. To begin the project, multiple designs were developed for the sensor array and wearable materials. These concepts were compared against …

Interview Of Naomi Cahn, June Carbone & Nancy Levit, Naomi Cahn, June Carbone, Nancy Levit, Claire Hill, Matthew T. Bodie

Minnesota Journal of Law & Inequality

No abstract provided.

Conferences, Lightbulbs, And Gender, June Carbone

Minnesota Journal of Law & Inequality

No abstract provided.

The Orb’S Eye: Seeing The National Security Implications Of Iris Based ‘Proof Of Humanity’, Elise Annett, James M. Keagle, James Giordano

Strategic Insights

This commentary examines the national security implications of iris-based biometric identity systems such as “The Orb,” a device designed to verify human users in an AI-saturated digital environment. While proof-of-personhood technologies may help counter synthetic media, bot networks, and AI-driven disinformation, the authors argue that centralized biometric identity infrastructures create significant strategic vulnerabilities. Risks include surveillance, coercion, identity forgery, cyber-espionage, financial manipulation, and potential use in cognitive warfare or critical infrastructure disruption. The article outlines governance and security recommendations to mitigate dual-use threats. Orb-like systems could either strengthen democratic resilience or become instruments of strategic influence, depending on how they …

Sociodemographic Influences On Substance Use In Psychosis In An African Cohort, Megan L. Campbell, Raymond Odokonyero, Dickens Akena, Melkam Alemayehu, Lukoye Atwoli, Lori B. Chibnik, Bizu Gelaye, Stella Gichuru, Symon M. Kariuki, Karestan C. Koenen

Internal Medicine, East Africa

Background: Substance use is common among individuals with psychotic disorders, but limited research exists on the variations in substance use across countries in Africa. This study aims to investigate the frequency of alcohol, tobacco, cannabis, and khat consumption in individuals with bipolar disorder (BD) and schizophrenia (SCZ) across four African countries: South Africa, Ethiopia, Kenya, and Uganda.

Methods: We utilized data from the Neuropsychiatric Genetics of African Populations-Psychosis project, a large case-control study which will soon have genetic data on over 42,000 participants, half with psychosis. Information on substance use was collected using the Alcohol, Smoking and Substance Involvement Screening …

A Descriptive Bibliometric Study Of Cera Publication Dissemination, Authorship, And Citation Rates., Bryce A Ringwald, Jennifer L Middleton

Medical Education Articles

BACKGROUND AND OBJECTIVES: Barriers to performing family medicine research include funding, infrastructure, and mentorship shortages. The Council of Academic Family Medicine Educational Research Alliance (CERA) was created in 2011 to address these issues. This study explores the scope and impact of CERA-related publications in family medicine.

METHODS: We performed a descriptive bibliometric study of CERA-related publications from 2011 to 2023. Articles were sourced from Medline (PubMed), SCOPUS, and the CERA website. Data analysis focused on publication type, authors, CERA survey type, and citation rates.

RESULTS: From a total of 231 articles retrieved via initial searches and 166 from the CERA …

Rattler Python, Samer Jabor

Systems Manuals - 2026

The Rattler Python project is an interactive game-based learning system that intends to teach the basic concepts of Python programming through guided instruction, gameplay challenges, and review-based assessments. The document contains a proposal for this system consisting of problem definition, background research, existing solutions, and the proposed product, together with the system scope, assumptions, and the organization of the remainder of this document.

Affordability: Practitioner Definitions And Perspectives From The Field, Molly Schnoke, Kristen A. Blazek

All Maxine Goodman Levin School of Urban Affairs Publications

What does Affordability mean when it comes to housing? The Center for Economic Development utilized housing data and stakeholder interviews to assess the county's housing needs. The study addresses challenges such as mismatched housing stock, an aging population, affordability issues, and programming difficulties.

First-In-Human Phase 1 Study Of Khk2455 Monotherapy And In Combination With Mogamulizumab In Patients With Advanced Solid Tumors, Timothy A Yap, Olivier Rixe, Capucine Baldini, Ursa Brown-Glaberman, Sergey Efuni, David S Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H Shiue, Yi Liu, Matthew W Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam

Faculty, Staff and Student Publications

Background: Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long-acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme. Mogamulizumab is a humanized immunoglobulin G1 monoclonal antibody targeting CCR4. KHK2455 + mogamulizumab demonstrated enhanced antitumor activity in preclinical studies, which led to a first-in-human, two-part, multicenter, open-label, phase 1, dose-escalation, cohort-expansion trial (ClinicalTrials.gov identifier NCT02867007) evaluating the safety/tolerability, pharmacokinetics, and IDO1 activity of KHK2455 alone and in combination with mogamulizumab in patients with treatment-refractory advanced solid tumors. …

Genome-Wide Association Meta-Analysis Of Human Olfactory Identification Discovers Sex-Specific And Sex-Differential Genetic Variants, Franz Förster, David Emmert, Katrin Horn, Janne Pott, Johannes Frasnelli, Mohammed Aslam Imtiaz, Konstantinos Melas, Valentina Talevi, Honglei Chen, Christoph Engel, Michele Filosi, Myriam Fornage, Martin Gögele, Markus Löffler, Thomas H Mosley, Cristian Pattaro, Peter Pramstaller, Srishti Shrestha, N Ahmad Aziz, Monique M B Breteler, Kerstin Wirkner, Markus Scholz, Christian Fuchsberger

Faculty, Staff and Student Publications

Smelling is a human sense, expressing strong sexual dimorphisms. We aim to improve the knowledge of the genetics of human olfactory perception by performing an exploratory genome-wide association meta-analysis of up to 21,495 individuals of European ancestry. By sex-stratified and overall analysis of the identification of twelve odours and an identification score, we discovered ten independent loci, seven of them novel, with trait-wise genome-wide significance (p <  5 × 10−8) involving five odours. Seven of these loci, including four novel ones, are also significant using a stricter study-wide significance threshold (p <  3.85 × 10−9). Loci were predominantly located within clusters of olfactory receptors. Two loci were female-specific while one was sex-differential with respective candidate genes containing androgen response elements. Two-sample Mendelian randomization was applied to search for causal relationships between sex hormones, odour identification and neurodegenerative diseases. A causal negative effect was detected for Alzheimer’s disease on the identification score. These findings deepen our understanding of the genetic basis of olfactory perception and its interaction with sex, prioritizing mechanisms for further molecular research.

Dietary Patterns, Serum Metabolites, And Risk Of Cardiovascular Disease In United States Hispanic/Latino Adults: A Prospective Analysis Of The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Hongbo Yang, Yi Wang, Kai Luo, Yasmin Mossavar-Rahmani, Christina Cordero, Robert J Ostfeld, Claudia Martinez, Luis Maldonado, Amber Pirzada, Martha Daviglus, Bing Yu, Frank B Hu, Robert C Kaplan, Qibin Qi

Faculty, Staff and Student Publications

Background: Healthy dietary patterns are recommended to prevent cardiovascular disease (CVD), yet the relationships among healthy dietary patterns, blood metabolite profile, and incident CVD are not well understood.

Objectives: This study aimed to assess the associations of healthy dietary patterns and related serum metabolite profiles with incident CVD in United States Hispanic/Latino adults.

Methods: The study included 13,922 participants aged 18-74 y from the Hispanic Community Health Study/Study of Latinos. Dietary pattern scores, including Healthy Eating Index (HEI)-2020, healthful Plant-based Diet Index (hPDI), and alternate Mediterranean diet score (aMED), were constructed at baseline (2008-2011) based on 2 24-h dietary recalls. …

Pulmonary Complications Associated With Sugammadex Or Neostigmine In Patients Recovering From Advanced Diagnostic Or Interventional Bronchoscopy: A Retrospective Two-Centre Analysis, Ehab Farag, Karan Shah, Maged Argalious, Basem Abdelmalak, Thomas Gildea, John Seif, Shuyi Li, Edward J Mascha, Daniel I Sessler

Faculty, Staff and Student Publications

Background: Many diagnostic and interventional procedures are performed in bronchoscopy suites in high-risk patients. Minor impairment in respiratory muscle function caused by incomplete reversal of neuromuscular block can contribute to postoperative pulmonary complications (PPCs). We assessed whether there are fewer serious PPCs after diagnostic or therapeutic bronchoscopy when neuromuscular block is reversed with sugammadex rather than neostigmine.

Methods: This is a retrospective cohort study for bronchoscopy under general anaesthesia with the use of neuromuscular blockers between July 2016 and June 2022. The primary outcome was a composite of PPCs. The secondary outcome was hypoxaemia. We used inverse probability of treatment …

Hybrid Deep Learning Approaches For Accurate Electricity Price Forecasting: A Day-Ahead Us Energy Market Analysis With Renewable Energy, Rahman Md. Saifur, Hassan Reza

Faculty, Staff and Student Publications

Forecasting day-ahead electricity prices is a crucial research area. Both wholesale and retail sectors highly value improved forecast accuracy. Renewable energy sources have grown more influential and effective in the US power market. However, current forecasting models have shortcomings, including inadequate consideration of renewable energy impacts and insufficient feature selection. Many studies lack reproducibility, clear presentation of input features, and proper integration of renewable resources. This study addresses these gaps by incorporating a comprehensive set of input features, while these features are engineered to capture complex market dynamics. The model’s unique aspect is its inclusion of renewable-related inputs, such as …

Course Descriptions, Saint Mary's College Of California

Undergraduate Academic Catalog

No abstract provided.

"I Don't Think Librarians Can Save Us": The Material Conditions Of Information Literacy Instruction In The Misinformation Age, Amber Willenborg, Robert Detmering

Faculty and Staff Scholarship

This national qualitative study investigates academic librarians’ instructional experiences, views, and challenges regarding the widespread problem of misinformation. Findings from phenomenological interviews reveal a tension between librarians’ professional, moral, and civic obligation to address misinformation and the actual material conditions of information literacy instruction, which influence and often constrain librarians’ pedagogical and institutional roles. The authors call for greater professional reflection on current information literacy models that focus on achieving ambitious educational goals but which may be unsuitable for addressing the larger social and political crisis of misinformation.

Investigation Of A Pathogenic Inversion In Unc13d And Comprehensive Analysis Of Chromosomal Inversions Across Diverse Datasets, Tugce Bozkurt-Yozgatli, Ming Yin Lun, Jesse D Bengtsson, Ugur Sezerman, Ivan K Chinn, Zeynep Coban-Akdemir, Claudia M B Carvalho

Faculty, Staff and Student Publications

Inversions are known contributors to the pathogenesis of genetic diseases. Identifying inversions poses significant challenges, making it one of the most demanding structural variants (SVs) to detect and interpret. Recent advancements in sequencing technologies and the development of publicly available SV datasets have substantially enhanced our capability to explore inversions. However, a cross-comparison in those datasets remains unexplored. In this study, we reported a proband with familial hemophagocytic lymphohistiocytosis type-3 carrying a splicing variant (c.1389+1G>A) in trans with an inversion present in 0.006345% of individuals in gnomAD (v4.0) that disrupts UNC13D. Based on this result, we investigate the features …

The Impact Of Household Dysfunction On Dating Violence Perpetration Among Adolescents In The United States: A Scoping Review, Sumaita Choudhury, Melissa F Peskin, Timothy J Walker, Emily T Hébert, Nivedhitha Parthasarathy, Kaitlyn L Zajack-Garcia, Lea Sacca, Christine M Markham

Faculty, Staff and Student Publications

Adverse childhood experiences, such as household dysfunction (HD), play a central role in how adolescents establish, experience, and navigate the challenges of relationship formation, maintenance, and dissolution. HD exposures have been independently associated with dating violence (DV) perpetration in both adolescents and adults. However, research examining the association between the concurrent effect of HD on DV perpetration, especially among adolescents remains scarce. Thus, we conducted a scoping review to accumulate and summarize existing research regarding the impact of HD on DV perpetration among adolescents aged 10 to 17 years in the United States. We used three electronic databases, Medline (Ovid), …

Unlocking The Neurochemical Secrets Of Aging: Investigating The Impact Of Gaba Producing Probiotics On Healthy Aging, Sanaly Nava, Isabel Harbig, Dishant Aggarwal, Samjhana Pradhan, Ken Aho, Kavita Sharma

Idaho Conference on Undergraduate Research

Aging is a gradual process of weakening bodily function that leads to decline in physical, cognitive and behavioral abilities. Gamma-amino butyric acid (GABA), a major neurotransmitter in the central nervous system, is produced by both neurons and gut bacteria, and plays a crucial role in numerous physiological functions. Notably, aging is associated with a decline in GABA production and alterations in gut microbiota. Therefore, restoring GABA production by correcting dysbiosis presents a potential strategy for managing age-related functional decline. To better understand how to support healthy aging, our study investigates the gut-brain axis and the potential of genetically modified GABA-producing …