Digital Commons Network^™

Beyond Atrial Fibrillation And Heart Failure: Ibrutinib-Induced Pericardial Effusion, Anaiya Singh, Kathryn Ruckstuhl, Viraj Panchal, Poornima Ramadas

Journal of Community Hospital Internal Medicine Perspectives

Ibrutinib, a Bruton’s tyrosine kinase inhibitor, has transformed the management of various hematological malignancies. However, its association with cardiovascular toxicities, particularly atrial fibrillation (AF), hypertension, and heart failure (HF), has raised clinical concerns. Pericardial effusion, though rare, is an emerging complication warranting attention. We present the case of a 62-year-old male with lymphoplasmacytic lymphoma, initially treated with Bendamustine and Rituximab, which was discontinued due to significant neutropenia. Ibrutinib therapy was initiated, leading to a partial response at three months. Approximately ten months into ibrutinib treatment, the patient developed new-onset dyspnea, palpitations, and dizziness. ECG revealed AF with rapid ventricular response, …

Pasteurella Multocida Bacteremia In A Patient With Chronic Liver Disease, Jose Orsini, Vladimir Sabayev

Journal of Community Hospital Internal Medicine Perspectives

Pasteurella multocida is a non-spore forming gram-negative organism characterized morphologically as coccobacillus. It is frequently isolated from the nasopharynx of domestic and wild animals, and is the most common cause of soft-tissue infection in humans following bites or scratches from dogs and cats. It is easily overgrowth by other flora in the sputum and may be regularly overlook, as it resembles Haemophilus influenzae, Francisella tularensis, and Yersinia pestis. The five species that cause the majority of pasteurellosis are: multocida, septica, canis, stomatis, and dagmatis. Pasteurella multocida is infrequently encounter in clinical settings, …

A Rare Case Of Familial Hypocalciuric Hypercalcemia In Patient With Pancreatitis, Muhammad Ijaz Khan, Tanvi Jain, Muhammad Mohsin Abid, Samra Israr, Muhammad Haris Khan

Journal of Community Hospital Internal Medicine Perspectives

Familial hypocalciuric hypercalcemia (FHH) is a rare autosomal dominant condition caused by mutations in the calcium-sensing receptor gene (CASR), leading to asymptomatic hypercalcemia. Here, we report a case of hypercalcemia in a patient with acute pancreatitis, subsequently diagnosed with FHH. A 41-year-old male presented with abdominal pain and elevated pancreatic enzymes. Imaging revealed changes consistent with acute pancreatitis. Surprisingly, serum calcium was elevated, which is uncommon in acute pancreatitis. Further work-up demonstrated normal parathyroid hormone (PTH), PTH-related peptide (PTHrp), and vitamin D levels. A 24- hour urinary calcium excretion of 24 mg/24 hr and a calcium-to-creatinine clearance ratio (CCCR) of …

An Unusual Presentation Of Iga Vasculitis And Iga Nephropathy: A Case Report, Mark A. Colantonio, Nicholas Condiles, Alan P. Lim, Khaled Shawwa

Journal of Community Hospital Internal Medicine Perspectives

Immunoglobulin A (IgA) nephropathy is the most common glomerulonephritis worldwide. While IgA nephropathy mainly presents with renal manifestations, systemic symptoms associated with vasculitis are uncommon. Oftentimes, creatinine is used as a serum marker for renal dysfunction; however, it may not always be sensitive, especially in patients with low muscle mass. In such cases, cystatin C may prove to be a better indicator of renal function. Here, we present a case of IgA nephropathy with a normal serum creatinine and elevated cystatin C, highlighting the utility of cystatin C in the setting of a normal creatinine and high suspicion for renal …

Hydralazine-Induced Anca-Associated Vasculitis With Lupus Nephritis Features And A Unique Antibody Profile, Mahiar Rabie, Melissa Scalise

Journal of Community Hospital Internal Medicine Perspectives

Drug-induced antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a condition caused by a few culprit medications, notably hydralazine. Despite the significant morbidity and mortality associated with this condition, its rarity makes timely diagnosis challenging. A 68 year-old female presented to her nephrologist for a routine follow up of her chronic kidney disease stage III secondary to hypertension. Routine lab work noted worsened creatinine and protein to creatinine ratios. Additionally, her hypertension became more difficult to control, and she suffered from malaise, poor appetite, joint aches/pains and lower extremity edema. Given her sudden worsening of renal function, a serologic investigation was …

Intradialytic Atrial Fibrillation With Rapid Ventricular Response From Catheter-Related Right Atrial Thrombus, Anish K. Shrestha, Sakthi Gautham, Shiavax J. Rao, Khalid K. Al-Talib, Sriram Padmanabhan

Journal of Community Hospital Internal Medicine Perspectives

Right atrial thrombus is a rare complication of hemodialysis catheter with an incidence of

The Diagnostic Maze: Challenges In Autoimmune Hepatitis Lab Interpretation, Tina C. L. Phan, Esther Blondeau-Lecomte, Christopher D. Jackson

Journal of Community Hospital Internal Medicine Perspectives

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease characterized by the presence of circulating autoantibodies. The spectrum of disease manifestations extends from asymptomatic cases to mild symptoms and, in rare instances, acute liver failure. AIH is a diagnosis of exclusion, supported by the detection of autoantibodies such as anti-smooth-muscle antibody (ASMA). This case describes a 43-year-old female with myasthenia gravis, receiving monthly intravenous immunoglobulin (IVIG) infusions, who presented with persistently elevated liver enzymes and mildly elevated ASMA titers across multiple clinical encounters. A liver biopsy revealed severe acute hepatitis. While drug-induced liver injury (DILI) secondary to IVIG was initially …

Diagnostic Challenges In Concurrent Primary Biliary Cholangitis And Secondary Syphilis: A Case Report, Rakahn Haddadin, Danny Aboujamra, Emon Javadi, Humzah Iqbal, Pinak Shah, Homayon Iraninezhad

Journal of Community Hospital Internal Medicine Perspectives

Concurrent Secondary syphilis and Primary Biliary Cholangitis (PBC) presenting with liver dysfunction is exceedingly rare, warranting detailed examination and documentation. Syphilis, a sexually transmitted infection, and PBC, an autoimmune liver disease, rarely coexist, let alone concurrently manifesting liver complications. Our case report delves into the intricacies of such a unique presentation, highlighting the challenges in diagnosis, management, and the implications for patient care.

Pulmonary Mycobactetrium Kumamotonense With Hepatosplenic Dissemination In An Immunocompetent Patient: A Case Report And Review, Michael S. Wang, Jeremiah Chang, Tiffany Whelan, Bo Liu, Katie Fitton, Jeffrey J Grondin

Journal of Community Hospital Internal Medicine Perspectives

We report a 69-year-old with a past medical history of prostate cancer and arsenic poisoning, who was incidentally found to have multiple pulmonary nodules and hepatosplenic lesions on CT imaging. He denied respiratory symptoms, but was noted to have significant weight loss. A bronchoscopy revealed mycobacterium kumamotonense on culture. He was treated presumptively for pulmonary and disseminated infection with azithromycin and ethambutol for 16 months, and 12 months of rifabutin after four months of rifampin which was discontinued due to resistance. Patient’s weight loss resolved and CT imaging appeared significantly improved.

When Patients Ask Chatgpt About Statins: Clinical Implications In The Community Setting, Jayashree Ravikumar

Journal of Community Hospital Internal Medicine Perspectives

No abstract for this article type.

The Role Of Sglt2 Inhibitors In Atherosclerosis: A Systematic Review, Mohammad Hamza Bin Abdul Maik, Muhammad Ibtisam, Sarah Sheikh, Muhammad Awais Bin Abdul Malik, Ayesha Ihsan, Muhammad Arham, Usman Haq, Abida Parveen

Journal of Community Hospital Internal Medicine Perspectives

Background

Atherosclerosis, a major cause of cardiovascular morbidity and mortality, involves lipid accumulation, endothelial dysfunction, inflammation, and oxidative stress. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, initially developed for type 2 diabetes mellitus (T2DM), have demonstrated cardiovascular benefits beyond glycemic control. Emerging evidence suggests their potential role in slowing atherosclerosis progression and enhancing plaque stability.

Methods

A systematic review of PubMed, Scopus, Embase, and Cochrane Library databases was conducted to identify preclinical and clinical studies on SGLT2 inhibitors and atherosclerosis. Studies published in English up to December 2024 were screened using predefined criteria. Data on mechanisms, lipid metabolism, endothelial function, vascular inflammation, and …

Acute Kidney Injury (Aki) In Adults With Leukemia: A Nationwide Inpatient Retrospective Analysis, Barath Prashanth Sivasubramanian, Sindhu Chandra Pokhriyal, Shashvat Joshi, Diviya Bharathi Ravikumar, Viraj Panchal, Ibthisam Ismail Sharieff, Tenzin Tamdin, Madhumithaa Jagannathan, Parvathy Anitha Rajeev, Idopise Umana

Journal of Community Hospital Internal Medicine Perspectives

Background: Leukemia ranks among the top three cancers in those who have Acute Kidney Injury (AKI), with an incidence of 7.5 % in hematological malignancies. Through this study, we aimed to assess the mortality of severe sepsis (SS), thrombocytopenia, and metabolic encephalopathy (MetE) in Leukemia with AKI.

Methods: We conducted a retrospective analysis using the National Inpatient Sample (2018e2021). Adults with Leukemia primarily admitted with AKI were included, and mortality was calculated. Patients were stratified by SS, thrombocytopenia, and MetE. Propensity matching for age over 60 and gender, and multivariate regression were performed with p ≤ 0.05.

Results: Among 388,449 …

The Association Of Non-Invasive Ventilation And Mortality In Covid-19 Induced Acute Respiratory Distress Syndrome, Chahat Puri, Akshay Duddu, Gina Patel, Sahib Singh, Juan Negrin, Lauren Greenburg, David Vitberg, Elisabeth M. Carr

Journal of Community Hospital Internal Medicine Perspectives

BACKGROUND - The COVID-19 pandemic caused a major burden on the healthcare system. Since the beginning of the pandemic, the timing of intubation in patients with COVID-19 induced acute respiratory distress syndrome (ARDS) remained an area of debate. STUDY DESIGN AND METHODS - A single-center, retrospective cohort study of all adult patients (n=161) with COVID-19 admitted to the ICU with acute hypoxic respiratory failure were included. The group was divided into patients intubated after a trial of NIV (N=100) and patients intubated without a trial of NIV (N=61). The primary outcome was to compare the mortality rates between the two …

Mortality And Readmission Outcomes For Intensive And Conventional Cardiac Rehabilitation (Mr-Oficr) Study, Yash Bharatkumar Patel, Agara Kumar, Marianne Huebner, Mohammed El Nayir, Anupam Suneja, Frank Smith

Journal of Community Hospital Internal Medicine Perspectives

Cardiac rehabilitation programs are offered in two major formats: Conventional Cardiac Rehab (CCR), which is primarily based on exercise interventions, and Intensive Cardiac Rehabilitation (ICR), which is a holistic approach including dietary modifications with a plant-based diet and wellness counseling. We performed a retrospective cohort study to compare the CCR and ICR groups for the primary composite outcome of Major Adverse Cardiac Event (MACE) at two years. The MACE outcome was 2-year mortality, unstable angina requiring hospitalization, Myocardial Infarction (MI), Coronary Artery Bypass Graft (CABG), Percutaneous Coronary Intervention (PCI), and stroke. Secondary outcomes were overall mortality, and number of readmissions. …

Ownership And Perceived Usefulness Of Digital Health Tools (Dht) For Health Promotion Among Individuals With Rheumatologic Diseases In The United States, Ufuoma Nene Mamoh, Soziema Juliet Salia, Joseph Okiemute Atarere, Andrew Kamsoko Ndakotsu, Alejandro Jaller, David S. Weisman

Journal of Community Hospital Internal Medicine Perspectives

Introduction: Research on digital health tools (DHT) use in RD patients is lacking.

Method: Data from the 2017 and 2018 Health Information National Trends Survey (HINTS) were used to compare DHT ownership and perceived usefulness between individuals with and without RD and to evaluate how health applications usage influenced health behaviors in RD patients.

Results: No significant differences in smartphone or health applications ownership were found between the groups. Among RD patients, older males and those with lower incomes were less likely to use DHT. DHT users reported better communication with healthcare providers, but no significant impact on health behaviors. …

Incidence, Associated Abnormalities, And Outcomes Of Dextrocardia: A Registry-Based Study In Saudi Arabia, Naif Saad Alghasab, Bandar Alshehri, Sulaman Almesned, Hassan Harbi, Reem Alameer, Fahad Alshehri, Ahmad Alzeid, Meshari Alzhrani, Ghazi T. Almutiri, Sara Abou Al-Saud, Fahad Alobaid, Khalid S. Alnajashi, Federica Fogacci, Arrigo F.G. Cicero, Suleiman M. Kharabsheh

Journal of the Saudi Heart Association

Objective: The right-sided positioning of heart during embryonic development is termed dextrocardia, and it may be isolated or associated with visceral dextroposition or malformation. However, there are few studies on the condition. This study aimed to determine the incidence of cardiac and non-cardiac malformations, long-term follow-up, and survival analysis of patients with dextrocardia. Methods: This was a retrospective chart review of dextrocardia cases at King Faisal Specialist Hospital & Research Centre in Riyadh, Saudi Arabia from April 22, 1975, to December 31, 2016. A total of 259,246 transthoracic echocardiograms from that period were reviewed, and 357 patients were included in …

Artificial Intelligence Policies In Bioethics And Health Humanities: A Comparative Analysis Of Publishers And Journals, Christopher Bobier, Daniel Rodger, Daniel Hurst

Rowan-Virtua School of Osteopathic Medicine Departmental Research

INTRODUCTION: Rapid advancements in artificial intelligence (AI) pose novel ethical and practical challenges for scholarly publishing. Although AI-related policies are emerging in many disciplines, little is known about the extent and clarity of AI guidance in bioethics and health humanities journals.

METHODS: A search of publicly available journal lists from the American Society for Bioethics and Humanities, Health Humanities Consortium, and Association for Medical Humanities was supplemented with Google Scholar's top 20 bioethics journals ranked by h5-index. This yielded 54 unique journals, of which 50 remained after excluding those without a functional website or recent publications. AI policies were reviewed …

Wrapped In The American Flag: Liberal Activism And Queer Political Organizing Post-1940s, Sam Markley

IdeaFest

By analyzing the United States Lavender Scare and immigration policy of the 1950s, this paper attempts to shed light on how the distinction between “American” and “Un-American” remains at the center of Queer rights advocacy. The heightened fear over the survival of the nation, along with the view of Queer immigrants as threats to the nation, was used to tighten immigration restrictions. This restriction, however, is complicated by existing prejudices against racial minorities and women. Queer rights groups began to rise to prominence during this time and mobilize against claims that they were anti-American or subversive deviants, working through the …

Building Belonging Infrastructure In Cities: Arts/Culture-Based Critical Participatory Action Research And Youth, Kimberly Rae Nightingale

Dissertations and Theses

Belonging is a critical human need. Urban planning's history of bureaucratic expertise continues to champion the powerful, resulting in structures and procedures that still separate and damage city communities. This research challenges the current hegemony of urban planning that centers geography--the container of land--in its practice. Instead, centering the belonging of people to each other is the essential quality of healthy urban planning. A people-centered urban planning practice where the community's people are the experts and decision-makers of their own cities--and belonging is the primary objective--is long overdue.

Arts/culture-based critical participatory action research (PAR)--where the research questions, design, data collection, …

Introduction To Sociology: Sociology - An Introduction, Dr. Marcia Morrison Ph.D.

Open Educational Resources

This comprehensive overview explores the foundational concepts, historical evolution, and seminal theorists of sociology, tracing its origins from the transformative revolutions of the 18th and 19th centuries to its modern-day significance. Central themes include the sociological imagination of C. Wright Mills, the complex interplay between individual experience and societal structure, and the pivotal roles of social structure, action, functional integration, power, and culture in shaping human relations. The discussion highlights the lasting contributions of early sociologists such as Auguste Comte, Adam Smith, Karl Marx, Émile Durkheim, Max Weber, and George Herbert Mead, examining how their theories continue to inform contemporary …

Introduction To Sociology: Interaction And Social Structure, Dr. Marcia Morrison Ph.D.

Open Educational Resources

Abstract

This paper explores the intricate interplay between micro- and macro-sociological perspectives on social interaction, identity, and structure. Through an examination of theoretical approaches such as symbolic interactionism, dramaturgy, and social exchange, it highlights how individuals construct and perform identities within complex webs of social expectations—particularly shaped by factors like race, status, and role dynamics. The discussion extends to the function of social networks in influencing opportunities, notably in the context of employment, underscoring the nuanced role of weak ties. The analysis further delves into the significance of social status, distinguishing between ascribed, achieved, master, and salient statuses, and examines …

Using Remote Behavioral Skills Training To Teach Staff To Implement Augmented Competing Stimulus Assessments, Tanvi Pendharkar

Doctoral Dissertations - College of Arts and Sciences

Despite a growing number of Board Certified Behavior Analysts^®(BCBA), there are many geographic regions without access to behavior analytic services. Remote training methods that can be implemented without face-to-face contact allow for behavior analytic services to reach areas without local BCBAs to provide services. One such method with promise for remote application is behavioral skills training (BST). BST consists of instructions, modeling, rehearsal, and feedback. BST has been used to train behavior-analytic service providers to implement a variety of procedures, but BST has yet to be used to teach clinicians how to conduct augmented competing stimulus assessments (A-CSA). …

Imaging Sciences Teachers’ Experiences With Simulation-Based Clinical Training Curriculum, Mandy Stelz

Walden Dissertations and Doctoral Studies

Simulation-based education (SBE) is currently being used in imaging sciences education with no set standards or best practices. Grounded in the framework drawn from Kolb’s experiential learning theory and Magana’s T3 framework of innovation, the purpose of this qualitative study was to explore imaging science teachers’ experiences using SBE for clinical training. The participants were 12 imaging science teachers that have taught imaging science students using SBE for a minimum of 3 years. Data were collected using semistructured interviews. Through thematic analysis, four themes were identified: (a) imaging science teachers reported a wide variety of tools and types of SBE …

Organizational Culture And Work Environment As Determinats Of Teacher Motivation: A Quantitative Study In Slb, Pekalongan Regency, Nur Kholifah, Widya Kusumaningsih, Nurkolis Nurkolis

Journal of ICSAR

This study examines the influence of organizational culture and work environment on the work motivation of Special Needs School (SLB) teachers in Pekalongan Regency. Using a quantitative descriptive-correlational approach, data were collected from 103 SLB teachers through a Likert-scale questionnaire. The results show that both organizational culture and work environment have significant and positive effects on teacher motivation, both partially and simultaneously. Organizational culture contributes 46% and work environment 56% to the variation in work motivation, while together they account for 58%. The highest contributions come from intrinsic motivation and the non-physical work environment. These findings emphasize the importance of …

Enhancing Thematic Learning Outcomes And Reducing Maladaptive Behaviors In Autistic Students Through The Busy Web Media, Hartini Nara, Rohmah Ageng Mursita, Ashi Thariq Jaatshiah

Journal of ICSAR

This study aims to develop Busy Web Media as a tool for thematic learning, designed to reduce maladaptive behaviours in autistic students in grade VI at Sekolah Matahari Bunda. Using the Research and Development (R&D) method in conjunction with the ADDIE model (Analysis, Design, Development, Implementation, Evaluation), the study involved expert evaluations at various stages. Media experts, content specialists, and autism experts provided their assessments, with all evaluations indicating high feasibility. Specifically, the media expert rated the product positively, emphasising its design and usability. The subject matter expert found the content highly appropriate for the curriculum, and the autism expert …

Determining Graduate Quality Through School Principals’ Transformational Leadership, Teachers’ Professional Competence, And Work Motivation: A Quantitative Study, Ana Supriati, Titik Haryati, Sumarno Sumarno

Journal of ICSAR

This study aims to analyze the influence of school principals’ transformational leadership, teachers’ professional competence, and work motivation on the quality of graduates in public junior high schools in Rembang Regency. A quantitative approach was employed using a survey method involving 289 teachers as respondents. The research instrument used a Likert-scale questionnaire tested for validity and reliability. Data were analyzed using multiple linear regression techniques. The results revealed that both partially and simultaneously, the three independent variables had a positive and significant influence on the quality of graduates. Transformational leadership fosters a supportive school climate, professional competence enhances teaching effectiveness, …

Toward Inclusive Higher Education: Challenges And Opportunities In Ten Asian Countries Following Crpd Ratification, Mohammad Idrees Naeemy, Hiroki Yoneda

Journal of ICSAR

The ratification of the Convention on the Rights of Persons with Disabilities (CRPD) has triggered a wave of policy initiatives aimed at inclusive higher education around the world. Yet the extent of progress remains unclear in Asian region. This systematic review fills that gap by analysing 46 peer-reviewed publications (2013–2024) that document post-CRPD developments in ten Asian countries—China, India, Iran, Japan, Kazakhstan, Malaysia, Pakistan, Singapore, Turkey and the United Arab Emirates. We mapped legislative reforms, organizational responses and structural adaptations designed to accommodate students with disabilities and compared the pace and depth of change across national contexts. The review revealed …

Digital Menstrual Health Education For Adolescent Girls With Intellectual Disabilities: Evidence From The Kesmens Digital Media Intervention, Ana Fatimatuzzahra, Endang Rochyadi, Riksma Nurhami Akhlan, Een Ratnengsih, Mughi Puspa Annisi

Journal of ICSAR

Adolescent female with intellectual disabilities often encounter substantial barriers in managing menstrual hygiene, which may negatively impact their physical health, social integration, and personal autonomy. These challenges are largely attributed to the absence of concrete and developmentally appropriate educational tools, along with limited support from families and educators during menstruation. This study evaluates the effectiveness of the KESMENS Digital Book, a family assisted multimedia learning resource, in improving menstrual hygiene management skills among adolescents with intellectual disabilities. Using a Single Subject Research method with an A B design, the intervention was implemented for a junior high school student at SLBN …

Effects Of Self-Monitoring On Teachers’ Behavior-Specific Praise And Students’ Behavior In A Center-Based Classroom, Samantha Walsh

Theses

The current study explores the effects of self-monitoring on teachers' use of behavior-specific praise (BSP) and its impact on student behavior in a center-based classroom. Self-monitoring, a cost-effective and time-efficient intervention, has been proven effective in previous research for enhancing educator performance. However, previous studies have often combined self-monitoring with other interventions, leaving a gap in understanding its effects in isolation. This study aims to replicate the work of Justus et al. (2023) by examining the impact of self-monitoring on paraprofessionals in a center-based classroom with students aged 6-10. Using a multiple baseline design across participants, three paraprofessionals were trained …

Correction: Turn-On Fluorescent Glucose Transport Bioprobe Enables Wash-Free Real-Time Monitoring Of Glucose Uptake Activity In Live Cells And Small Organisms, Monica S. Hensley, David Hutchings, Abdelrahman Ismail, Micaela Rayne Geborkoff, Thomas Werner, Marina Tanasova

Michigan Tech Publications

Correction for “Turn-on fluorescent glucose transport bioprobe enables wash-free real-time monitoring of glucose uptake activity in live cells and small organisms” by Monica S. Hensley et al., RSC Chem. Biol., 2025, 6, 987–995, https://doi.org/10.1039/D4CB00239C.

The authors regret that two contributors, Micaela Rayne Geborkoff and Professor Dr Thomas Werner, were inadvertently omitted from the original author list of this article. Both individuals made significant contributions to the research reported.

Micaela Rayne Geborkoff was involved in the design, planning, and execution of the Drosophila experiments, specifically in the growth and treatment of fruit fly larvae. Professor Dr Thomas Werner provided …