Digital Commons Network^™

Psychopharmacological Therapy Positively Modulates Disease Activity In Inflammatory Bowel Disease: A Systematic Review, Federica Di Vincenzo, Antonio Maria D'Onofrio, Angelo Del Gaudio, Elena Chiera, Gaspare Filippo Ferrajoli, Francesco Pesaresi, Alessio Simonetti, Marianna Mazza, Georgios Demetrios Kotzalidis, Mauro Pettorruso, Giovanni Martinotti, Loris Riccardo Lopetuso, Antonio Gasbarrini, Gabriele Sani, Gionata Fiorino, Franco Scaldaferri, Giovanni Camardese

Faculty, Staff and Students Publications

Depression, anxiety, and perceived stress are common comorbidities in patients with inflammatory bowel disease (IBD) and may negatively influence the disease course. Likewise, severe IBD may contribute to the development or worsening of psychiatric symptoms. Despite the established relevance of the gut-brain axis and frequent use of psychotropic medications in IBD patients, limited evidence exists regarding the effects of psychiatric treatments on gastrointestinal disease activity. Therefore, the aim of this systematic review is to evaluate the effectiveness of psychiatric therapies on gastrointestinal symptoms and disease activity in patients with IBD. The work was conducted in accordance with PRISMA guidelines. Searches …

Dopamine Partial Agonists In Pregnancy And Lactation: A Systematic Review, Alexia Koukopoulos, Delfina Janiri, Miriam Milintenda, Sara Barbonetti, Georgios D Kotzalidis, Tommaso Callovini, Lorenzo Moccia, Silvia Montanari, Marianna Mazza, Lucio Rinaldi, Alessio Simonetti, Mario Pinto, Giovanni Camardese, Gabriele Sani

Faculty, Staff and Students Publications

Background/Objectives: Dopamine partial agonists are drugs initially developed to treat schizophrenia, seeking a double effect of increased dopaminergic transmission in the prefrontal cortex and decrease in the accumbens/striatum. Of these drugs, aripiprazole, brexpiprazole, and cariprazine are currently marketed and used in schizophrenia spectrum and mood disorders. It is debated whether patients with psychiatric disorders becoming pregnant should discontinue or continue their antipsychotic treatment despite some risks for the fetus, i.e., whether it is worse to have an untreated disorder or treating it with drugs. The safety of drugs for mother and baby extend from pregnancy to the postpartum, when …

Small Policy Changes Can Accelerate The Adoption Of Improved On-Farm Storage Among Smallholder Farmers, Michael Brander, Zewdu Abro, Menale Kassie, Wolfgang Mittmann, Lukas Stiefel, Matthias Huss

All Peer-Reviewed Publications

Reducing food losses is a significant and often overlooked opportunity to bolster global food security and enhancing the resilience and sustainability of global food systems. Food losses are highest in low-income countries where millions of smallholder farming households remain particularly vulnerable. As yet, smallholders’ adoption of loss-minimizing storage technologies, such as hermetic storage bags, remains low. Here, we study the effects of two types of policy options on the adoption of improved on-farm storage in the case of Ethiopia. Using a randomized controlled trial, we show that a small partial subsidy, which mirrors the current fiscal burden on these technologies, …

Fire In The Hole: Appalachia’S Elemental Narrative In Harlan County, Usa And King Coal, Somak Mukherjee

Critical Humanities

In Elaine McMillion Sheldon’s documentary King Coal (2023) coal is being referred to as a matter that is “not dirty or clean, but elemental.” The acclaimed film centers on the complex histories and cultures of coal in Central Appalachia, based on the perspective of Sheldon, a coal miner’s daughter, and a West Virginia native. The elemental nature of coal is explored in the film by situating coal less as a resource and more as a mythic foundation for the community's cultural history. This article puts King Coal in conversation with Barbara Kopple's seminal Harlan County, USA (1976) which narrates the …

Planetary Thinking: Hellbenders As Emissaries Of Appalachia, Tierra R. Curry

Critical Humanities

Hellbenders are prehistoric salamanders that have thrived in cold rivers since before the continents divided. Once found throughout Appalachian watersheds, due to exploitation and habitat degradation only a few dozen healthy populations survive. Monstrous yet fascinating, hellbenders were often reviled historically, but in recent decades they have gained iconic status and are now celebrated as charismatic indicators for clean rivers. Hellbenders are symbols of the wild because of their ancient history, elusive nature, and contribution to ecosystem resilience. The same forces that drove the decline of these amphibian sentinels have sacrificed public health in Appalachia. Their demise echoes the struggle …

“Here’S To The Long Haul: Dark Green Religion And Planetary Thinking In Appalachian Environmental Movements”, Joseph Witt

Critical Humanities

Environmental humanities scholars have worked to develop alternative frameworks for understanding and relating to Earth’s systems in the hope of reforming the exploitative and extractive practices and attitudes characteristic of the Anthropocene. For example, Dipesh Chakrabarty argued that addressing climate change necessitated appreciating the entanglements between global (human) and planetary (Earth systems) scales. While Chakrabarty noted that ancient and Indigenous cultures may have retained approaches necessary for this work, he was skeptical of the ability of modern secular intellectual traditions focused on global justice perspectives to ultimately facilitate a planetary non-anthropocentric ethic. However, by only briefly engaging with themes of …

Planetary [] Appalachia: Editor’S Introduction, Scott C. Mcdaniel

Critical Humanities

Editor's Introduction to Volume 4 Issue 1

Bankruptcy Tax Act Of 1980 (Part Iii), David A. Bereson, Ernest Honecker

Tax Adviser

No abstract provided.

The Tax Adviser, Volume 12, Number 4, April 1981, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Estate Planning: Significant Recent Developments Concerning Estate Planning (Part I), Byrle M. Abbin, David K. Carlson

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

The Tax Adviser, Volume 13, Number 4, April 1982, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Taxation Of Group-Term Life Insurance: Sec. 79 History, Denise Lamaute

Tax Adviser

No abstract provided.

Planning And Tax Considerations In The Use Of Revocable Trusts (Part Iii), Julian S. Bush, Howard M. Zaritsky

Tax Adviser

No abstract provided.

Endowment Honors Musgrove Education Legacy, Tina H. Hahn

University of Mississippi News

OXFORD, Miss. – The late Melody Bruce Musgrove worked to create an education system to provide opportunity and equality for every child in Mississippi and the United States. That legacy is being expanded through the first endowed faculty chair in the University of Mississippi School of Education.

Exploring Sex-Specific Clinical Features In Chinese Patients With Takotsubo Syndrome, Hong-Yi Duan, Kan Liu, Et Al.

2020-Current year OA Pubs

BACKGROUND: Takotsubo syndrome (TTS) is considered as a transient acute heart failure syndrome predominant in females. However, data on Chinese TTS patients are limited. Therefore, this study aimed to investigate the clinical characteristics of Chinese TTS patients, identify prognostic markers.

METHODS: A total of 258 TTS patients were enrolled. Data on clinical characteristics and in-hospital major adverse cardiovascular events (MACE) were collected and analyzed. The latter included severe heart failure, shock, malignant arrhythmia, and death.

RESULTS: The average age of TTS patients was 59.3 ± 19.2 years. Female patients accounted for 68.9%. MACE occurred in 41.4% of patients during hospitalization. …

The Creation And Evaluation Of An Engineering Student Leadership Academy, Jean Mclaughlin, Thuy Vu, Seokmin Kang

Teaching and Learning Faculty Publications

This article describes the creation and evaluation designed to support student success through their inclusion in a variety of professional and technical training programs. The opportunity to develop a leadership academy specifically for engineering students allowed faculty program coordinators to deliver content that was normally not available to students at this Hispanic-Serving Institution (HSI). We implemented and evaluated the leadership academy using a mixed-methods approach involving multimedia interviews and two traditional survey data collection techniques. Traditional online surveys gave quick feedback to coordinators on what the students found valuable, with the biggest change in programming being the spreading out of …

Craig L. Robinson

African American Funeral Programs

Craig_L_Robinson.pdf - Funeral program for Craig Robinson

Latine Students’ Stem Identity Development: Reflecting On Implicit Biases, Imposter Syndrome, Self-Efficacy, And Support Systems, Alyssa G. Cavazos, Valerie Leija, Javier Cavazos Vela

Writing and Language Studies Faculty Publications

This study used an equity ethic framework and a STEM identity model to contextualize and understand Latine students’ perceptions of STEM identity development. The purpose of this study was to investigate how Latine undergraduate students who engaged in STEM coursework perceived their learning experiences and stories of resilience through an equity ethic framework. Data were collected through interviews with 19 Latine college students attending a Hispanic-Serving Institution. Findings revealed the following themes related to Latine students’ STEM identity development and lived experiences in STEM coursework: implicit biases, imposter syndrome, self-efficacy, and support system and resources. Findings highlight the need for …

Determinants Of Campylobacter Species Diversity In Infants And Association With Family Members, Livestock, And Household Environments In Rural Eastern Ethiopia, Amanda Ojeda, Mark J Manary, Et Al.

2020-Current year OA Pubs

BACKGROUND: Campylobacter infections pose a significant challenge in low- and middle-income countries, contributing to child mortality. Campylobacter is linked to acute gastrointestinal illness and severe long-term consequences, including environmental enteric dysfunction (EED) and stunting. In 2018, our cross-sectional study in Ethiopia detected Campylobacter in 88% of stools from children aged 12-15 months, with an average of 11 species per stool using meta-total RNA sequencing. Building on these findings, we conducted a longitudinal study (December 2020-June 2022) to investigate Campylobacter colonization of infants and identify reservoirs and risk factors in rural eastern Ethiopia.

RESULTS: After a preliminary screening of 15 Campylobacter …

Farewell To An Idea- The Coming End Of Tiered Scrutiny, Stephen Smith

Faculty Publications

No abstract provided.

Preliminary Investigation Of The Association Between Epigenetic Aging Acceleration And Amyloid Biomarkers In Bipolar Disorder, Gabriel R Fries, Steven De La Garza, Ning O Zhao, Andres W Bass, Camila N C Lima, Nobuhide Kobori, Tatiana Barichello, Gustavo Turecki, Paul E Schulz, Breno S Diniz, Jair C Soares

Faculty, Staff and Student Publications

Objectives: Bipolar disorder (BD) has been associated with an elevated risk of Alzheimer's Disease (AD). We assessed AD biomarkers in BD and tested whether epigenetic aging (EA) acceleration is associated with changes in these markers.

Design, setting, participants: Cross-sectional study of n = 58 living individuals with BD and n = 20 age- and sex-matched control participants, as well as analyses of postmortem brain samples (Brodmann area 9/46) from n = 46 individuals with BD.

Measurements: Amyloid beta (Aβ)40, Aβ42, and total Tau levels were measured in plasma from individuals with BD and controls, and Aβ42 levels were measured in …

Hikikomori Risk In The Uk, Gregory Gorman, Alison Bacon, Jon May, Stephen Minton

School of Psychology

Background: Hikikomori syndrome involves voluntary withdrawal from social life, school and work, with onset typically in young adulthood. Hikikomori risk has not been examined in the UK, and these studies aimed to validate and refine the Hikikomori Risk Inventory-24 (HRI-24) screening tool in UK young adults. Methods/Results: In Study 1, participants (n = 341) completed the HRI-24. Item analysis and confirmatory factor analysis resulted in a shorter 13-item HRI (HRI-13), which demonstrated a perfect correlation with the full HRI-24. Both the HRI-13 and HRI-24 showed strong convergent and divergent validity, correlating with depression, anxiety, avoidant coping and negative early life …

Pan-Cancer, Multi-Omic Correlates Of Survival Transcending Tumor Lineage Across 11,019 Patients Reveal Targets And Pathways, Yiqun Zhang, Fengju Chen, Chad J Creighton

Faculty, Staff and Students Publications

Molecular correlates of cancer patient overall survival (OS) can provide new insights. Here, we systematically cataloged pan-cancer, multi-omic correlates of OS transcending tumor lineage across 11,019 patients, involving multiple cancer types while correcting for cancer-type-intrinsic OS differences. Significant fractions of genes with mRNA associated with OS in pan-cancer analyses showed concordant associations at the levels of DNA copy number alteration or methylation. Pan-cancer gene signatures of T-cell and macrophage tumor infiltrates were associated with better and worse OS, respectively. Pathways implicated by molecular OS associations included metabolism, PI3K/Akt, Wnt, and TGF-beta receptor. Significant fractions of worse OS-associated genes were essential …

Prediction Of Generalized Anxiety Disorder Treatment Outcomes With Neurobehavioral Responses To Approach-Avoidance Conflict: A Randomized Clinical Trial., Hannah Berg, Timothy J. Mcdermott, Rayus Kuplicki, Hung-Wen Yeh, Wesley K. Thompson, Ryan Smith, Elisabeth Akeman, Namik Kirlic, Ashley Clausen, Mallory Cannon, Evan White, Christopher R. Martell, Kate B. Wolitzky-Taylor, Michelle G. Craske, James L. Abelson, Martin P. Paulus, Robin L. Aupperle

Manuscripts, Articles, Book Chapters and Other Papers

Treatments for generalized anxiety disorder (GAD) often aim to address maladaptive approach-avoidance behavior patterns. Approach-avoidance conflict (AAC) offers a potential framework for identifying treatment outcome predictors and informing optimization of GAD treatment. The current study examined whether pre-treatment neurobehavioral AAC indices predict symptom improvement in behavioral activation (BA) and exposure therapy (EXP) for GAD. Treatment-seeking adults meeting criteria for GAD completed a randomized clinical trial with pre-treatment blinding, conducted from 2016-2021. Participants were randomized to complete 10 manualized sessions of BA or EXP. Participants completed an AAC task during functional magnetic resonance imaging pre-treatment. Computational parameters of task behavior were …

Exploring Sex-Specific Clinical Features In Chinese Patients With Takotsubo Syndrome, Hong-Yi Duan, Ling-Lin Wang, Ling-Chun Lyu, Zhen-Hua Shi, Xiao-Ping Lin, Zheng-Yang Yu, Guo-Hua Fan, Jing Chen, Xin-Hong Yang, Wei Deng, Chang-Wu Xu, Yan Huang, Qing Zhou, Jin-Ling Chen, Hong-Ning Song, Dong Hu, Jin-Qiu Liu, Hector Barajas-Martinez, Charles Antzelevitch, Kan Liu, Hong Jiang, Dan Hu

Department of Medicine Faculty Papers

BACKGROUND: Takotsubo syndrome (TTS) is considered as a transient acute heart failure syndrome predominant in females. However, data on Chinese TTS patients are limited. Therefore, this study aimed to investigate the clinical characteristics of Chinese TTS patients, identify prognostic markers.

METHODS: A total of 258 TTS patients were enrolled. Data on clinical characteristics and in-hospital major adverse cardiovascular events (MACE) were collected and analyzed. The latter included severe heart failure, shock, malignant arrhythmia, and death.

RESULTS: The average age of TTS patients was 59.3 ± 19.2 years. Female patients accounted for 68.9%. MACE occurred in 41.4% of patients during hospitalization. …

Enhancing Image Denoising Performance Through Cosine Similarity-Based Block Matching And Adaptive Thresholding - Ca-Ebm3d, R. Padmapriya, A. Jeyasekar

Iraqi Journal for Computer Science and Mathematics

Image denoising plays a vital role in enhancing visual quality by effectively suppressing noise while retaining critical image structures and textures. Traditional Block-Matching and 3D (BM3D) Filtering techniques, although widely adopted, often encounter challenges in achieving an optimal trade-off between noise reduction and feature preservation due to limitations in fixed-thresholding strategies and suboptimal block matching. To address these shortcomings, this study introduces a novel Cosine Adaptive BM3D (CA-BM3D) approach, which integrates cosine similarity for more accurate block matching and incorporates adaptive thresholding to enhance denoising efficiency. The proposed method was evaluated on six standard 8-bit grayscale images such as Leena …

From Industrial Automation To Intelligent Automation: The Impact Of Iiot On Process Control - A Review?, Ali S. Allahloh, Mohammad Sarfraz, Duraid Y. Mohammed, Nadeen Khaleel Ibrahim, Hayder Hussein Thary

Iraqi Journal for Computer Science and Mathematics

The Industrial Internet of Things (IIoT) is reshaping process control, turning torrents of plant data into near-instant insight. Field evidence already shows unplanned-downtime cuts of 55%, maintenance-budget savings of 40%, and gains in overall-equipment-effectiveness of roughly 15%; nevertheless, fewer than 30% of facilities have pushed beyond pilot scale to full, always-on predictive maintenance. To clarify why, this review screens 312 Scopus records published between 2010 and 2023, then subjects 62 peer-reviewed studies and a broad set of industry reports to deep content analysis, bibliometric mapping, and thematic clustering.The results reveal four tightly connected research fronts—IIoT/Industry 4.0 core technologies, classical process-control …

Diagnosis Of Covid-19 And Viral Pneumonia With Chest X-Ray Images Using Resnet-34, Sudhir Anakal, Krishna Prasad K, Chandrashekhar Uppin, Dileep Kumar M

Iraqi Journal for Computer Science and Mathematics

COVID-19 is a highly contagious viral infection that primarily affects the respiratory system, causing symptoms such as high fever, cough, and severe respiratory distress. Early detection of the disease is of utmost importance to control the spread and severity. Common diagnostic methods include Reverse Transcription Polymerase Chain Reaction (RT-PCR), antigen tests, chest X-rays, and computed tomography (CT) scans. Similarly, viral pneumonia, another severe lung infection, leads to fluid or pus accumulation in the lungs, causing symptoms such as chest pain, fatigue, excessive sweating, and nausea. The elderly and young children are particularly vulnerable to severe complications. Similarly, viral pneumonia, another …

Efficacy And Rationale Of Differentiated Racecadotril Doses Combined With Bifidobacterium Triple Viable In Managing Pediatric Persistent Diarrhea: A Comprehensive Analysis, Yanrong Liu, Li Ma, Dian Jin, Jingli Peng, Han Wei, Xueyun Zhang, Yajing Wu

Journal of Pediatric Infectious Diseases

Objective: Pediatric persistent diarrhea poses a severe burden on children's health. This study investigates the efficacy and fundamental mechanisms of varying doses of racecadotril in combination with bifidobacterium triple viable for treating this condition in children. Methods: Employing a randomized controlled trial design, participants diagnosed with pediatric persistent diarrhea were randomly allocated to a high-dose group (observation) and a low-dose group (control), both treated with racecadotril combined with bifidobacterium triple viable. During treatment, clinical parameters were meticulously recorded and analyzed. ELISA techniques were utilized to quantify alterations in immune, inflammatory, and oxidative stress markers in serum. Quantitative culture methods for …