Digital Commons Network^™

Strategic Development Plan – San Pedro Dr. Main Street Corridor, Adrian N. Carver

Student Publications

The San Pedro MainStreet Strategic Development Plan is a place-based, community-driven roadmap for revitalizing the San Pedro Drive corridor in Albuquerque, New Mexico. The corridor sits at the intersection of historical significance and present-day opportunity—bridging the old and new alignments of Route 66 while serving a diverse, working-class population. Drawing from urban planning theory, spatial analysis, and community input, this plan identifies challenges and assets related to land use, infrastructure, business development, housing, and cultural identity. Special attention is given to past and ongoing patterns of racialized disinvestment and displacement, with strategies proposed to ensure equitable reinvestment and climate resilience. …

Access Research Materials Hslic Doesnt Own: Document Delivery & Interlibrary Loan, Evelyn Wang

HSLIC Faculty and Staff Instructional Resources

This informational flyer, "Access Research Materials HSLIC Doesn’t Own: Document Delivery & Interlibrary Loan," outlines the services available at the University of New Mexico Health Sciences Library and Informatics Center (HSLIC) for obtaining research materials not held by the library. It explains the difference between Interlibrary Loan (ILL)—borrowing materials from other libraries—and Document Delivery—electronic delivery of HSLIC-owned materials. The flyer details eligibility, costs, request procedures, delivery timelines, and support contacts for both services, aiming to help users efficiently access needed articles, book chapters, and more.

Electrochemical Properties Of Rhodium-Plated Esthetic Orthodontic Archwires, Michael Hoy

Master's Theses (2009 -)

Objective: Esthetics are becoming more important to patients with increased desire for ceramic brackets as they go through orthodontic treatment. Despite ceramic brackets offering an esthetic option for patients, traditional metal wires are still most commonly being used. Very little research on rhodium plated wires, specifically the American Orthodontics Iconix Aesthetic Arch Wire, exists in the literature with no tests of corrosion through electrochemical testing. The objective of this research is to analyze how rhodium plating affects the electrochemical properties of nickel-titanium (NiTi) orthodontic wires. Methods: Rhodium-plated NiTi orthodontic wires (Iconix Aesthetic; American Orthodontics) and non-plated NiTi orthodontic wires (NT3 …

The Parthenon, July 09, 2025, Baylee Parsons, Kaitlyn Fleming, Ashton Pack, Nate Harrah, Soleil Woolard

The Parthenon

No abstract provided.

Faculty Perceptions Of The Affective Domain In Entry-To-Practice Respiratory Therapy Education: An Exploratory Descriptive Qualitative Study, Jackie W. Davis

Graduate Theses, Dissertations, and Capstones

Background: The affective domain of learning is one of the three learning domains that comprise Bloom's Taxonomy of learning. The respiratory therapy profession places a great emphasis on the development and assessment of all three learning domains in entry-to-practice respiratory therapy education. While the cognitive and psychomotor domains receive significant attention, the affective domain of learning is often given less attention due to its complexity and lack of definition in the profession. Purpose: An exploratory descriptive qualitative study focused on exploring the affective domain of learning in entry-to-practice respiratory therapy education, specifically how the domain is defined, and …

Clinical & Educational Librarian Services, Evelyn Wang

HSLIC Faculty and Staff Instructional Resources

This informational handout, "Clinical & Educational Librarian Services: Training, Onsite Support, and Research Guidance," summarizes the key services provided by the Health Sciences Library and Informatics Center (HSLIC) for clinical and educational support. The document outlines tailored training sessions aligned with ACGME Milestones, onsite support for real-time literature searches and resource introductions during rounds and academic meetings, research guidance for developing questions and managing citations, and group workshops on databases and research tools. Contact information for scheduling consultations and requesting literature searches is included.

Zotero Citation Management: Streamline Your Research And Writing, Evelyn Wang

HSLIC Faculty and Staff Instructional Resources

No abstract provided.

Comprehensive Review On Facets Of Cloud Computing In Context Of Security And Privacy, Saurabh Aggarwal, Ashish Khanna, Abhilash Maroju

Polytechnic Journal

The advent of information and communication technologies (ICT) has increased the appeal of cloud computing, allowing enterprises scalability and a pay-as-you-go pricing model. Cloud adoption is hampered by the serious security and privacy issues that arise when data and apps are outsourced to unaffiliated cloud providers. Many of the security solutions put out by researchers and organisations are unable to effectively handle numerous threats without going against the goals of cloud security. While security and privacy issues are frequently highlighted in the literature, there aren't many thorough technological answers available to successfully reduce these threats. However, studies that provide technological …

Understanding Youth Violence Through A Socio-Ecological Lens, Yok-Fong Paat, Kristopher Hawk Yeager, Erik M. Cruz, Rebecca Cole, Luis R. Torres-Hostos

School of Social Work Faculty Publications

Youth violence—the deliberate use of physical force or harm by young people between the ages of 10 and 24 to intimidate or cause harm to others, both online and offline—is a critical public health issue in the United States. Yet, successfully predicting future violent offenders is a complex and challenging task, as the question of why some youths resort to extreme violence while others refrain from it—despite facing similar risk factors—remains widely debated. This article highlights both risk and protective factors of youth violence through a socio-ecological lens to offer a comprehensive understanding of the multifaceted factors driving youth violence …

Artificial Intelligence In Stem Education: A Transdisciplinary Framework For Engagement And Innovation, Cristo Leon Ph.D., James Lipuma Ph.D., Xavier Oviedo Torres

STEM for Success Resources

This peer-reviewed article, Artificial Intelligence in STEM Education: A Transdisciplinary Framework for Engagement and Innovation by Cristo León, James Lipuma, and Xavier Oviedo-Torres, published in Frontiers in Education, examines how artificial intelligence (AI) is transforming STEM education through a transdisciplinary lens. Based on a systematic review of 41 scholarly studies (2020–2025), it analyzes AI integration in STEM classrooms, focusing on learner agency, adaptive assessment, and ethical challenges such as algorithmic transparency, equity, and inclusion. Guided by a Transdisciplinary Communication (TDC) framework and grounded in PRISMA protocols, the study applies tools like Nvivo, Excel, and VOSviewer for thematic coding and …

From Novice To Expert: Preparing Your Peer Review, Diana M Proctor, Rachy Abraham, Shannon Esher Righi

Faculty, Staff and Student Publications

Peer review is the process by which the quality of scholarly work is assessed prior to being published, presented, or funded. The consequences of flawed research entering the public domain in the "post-truth" era highlight the need to improve peer review quality, which we believe can be achieved by standardizing training. Here, we aim to enhance the quality of published literature by presenting a systematic guide to train new reviewers (and aid experienced ones) in the art of peer reviewing the rigor of scientific manuscripts.

Parents Of Adolescents On Electronic Use And Attention Deficit Hyperactivity Disorder: Parental Perspectives, Sleep, Internalization, Jessica Wiepking

Walden Dissertations and Doctoral Studies

ADHD in adolescents is a common diagnosis, with exposure to daily electronic use. There is strong evidence for a relationship between electronic use and ADHD in adolescents. However, there is a gap on electronic use, internalized feelings, and sleep behaviors in ADHD adolescents and how sleep behaviors might impact that relationship. ADHD has its core symptoms that impact the individual daily. These symptoms need to be taken into consideration when looking at internalized feelings and sleep behavior patterns. The theoretical framework that aligns with this study is the Dopaminergic Dysregulation Theory (DDT). This theory is a module that suggests that …

Qualitative Insights Into Drug Use Safety Strategies And Social Support Among Sexual Minority Women Who Inject Drugs In Baltimore, Maryland, Jennifer L. Glick, Leanne Zhang, Aimee Huang, Megan Nguyen, Danielle German

School of Public Health Faculty Publications

Background: Sexual minority women (SMW) experience higher rates of substance use relative to heterosexual women in the U.S. but remain an under-studied population. SMW who inject drugs (SMWWID) navigate an unpredictable drug market and may experience complex relationships within their social spheres. We explore cisgender SMWWID’s strategies to maintain safety while injecting drugs, and the influence of their social support systems on those strategies. Methods: We conducted N = 16 phone-based, semi-structured, in-depth interviews with SMWWID in Baltimore, Maryland between June-October 2021. The interviews explored participants’ sexual orientation and gender identities, social networks and support systems, drug use behaviors and …

Cup Contamination: Research Reveals Alarming Microplastic Levels In Beverages, Dustin Roberto

HSC Newsroom

No abstract provided.

Concentration And Composition Of Organic Contaminants In Blackfin Tuna, Yellowfin Tuna, And The Common Clubhook Squid In The Western Gulf Of Mexico, Lisa Rose-Mann

USF Tampa Graduate Theses and Dissertations

Cephalopods are an important component of pelagic food webs. They play ecological roles not only as predators but also as prey. However, their role as prey in the trophic transfer of organic contaminants to apex predators such as tunas in the Gulf of Mexico (GoM) is not well known. To investigate the importance of cephalopods in tuna diets, stomach samples were collected in February 2020 from tunas caught by rod and reel aboard the F/V Gulf Eagle near two large offshore floating oil/gas platforms in the northwestern GoM. Cephalopod samples were obtained from gut content analysis of 41 tunas caught …

Documents From The July 9, 2025 Meeting Of The University Of Montana Staff Senate, University Of Montana--Missoula. Staff Senate

University of Montana Staff Senate Meeting Minutes

Agenda and meeting minutes from the July 9, 2025 meeting of the University of Montana Staff Senate.

Systematic Analysis Of Nonsense Variants Uncovers Peptide Release Rate As A Novel Modifier Of Nonsense-Mediated Mrna Decay, Divya Kolakada, Rui Fu, Nikita Biziaev, Alexey Shuvalov, Mlana Lore, Amy E Campbell, Michael A Cortázar, Marcin P Sajek, Jay R Hesselberth, Neelanjan Mukherjee, Elena Alkalaeva, Zeynep H Coban-Akdemir, Sujatha Jagannathan

Faculty, Staff and Student Publications

The phenotypic impact of nonsense variants is determined by nonsense-mediated mRNA decay (NMD), which degrades transcripts with premature termination codons (PTCs). Despite the clinical importance of nonsense variants, transcript-specific and context-dependent variations in NMD activity remain poorly understood. Here, we show that the amino acid preceding the PTC strongly influences NMD activity. Glycine codons promote robust NMD efficiency and show striking enrichment before PTCs but are depleted before normal termination codons. Glycine-PTC enrichment is particularly pronounced in genes tolerant to loss-of-function variants, suggesting efficient elimination of truncated proteins from nonessential genes. We further demonstrate that the peptide release rate during …

Wdr2 Regulates The Orphan Kinesin Kin-G To Promote Hook Complex And Golgi Biogenesis In Trypanosoma Brucei, Qing Zhou, Huiqing Hu, Ziyin Li

Faculty, Staff and Student Publications

The flagellum in Trypanosoma brucei plays crucial roles in cell locomotion, cell morphogenesis, and cell division, and its inheritance depends on the faithful duplication of multiple flagellum-associated structures. One of such cytoskeletal structures is a hairpin-like structure termed the hook complex, composed of a fishhook-like structure and a centrin arm structure, whose cellular functions remain poorly understood. We recently identified KIN-G, an orphan kinesin that promotes hook complex and Golgi biogenesis. Here we report a WD40 repeat-containing protein named WD40 Repeat-containing protein 2 (WDR2), which interacts with and regulates KIN-G. WDR2 co-localizes with KIN-G at the centrin arm, and knockdown …

Intracranial Directed Connectivity Links Subregions Of The Prefrontal Cortex To Major Depression, John Myers, Jiayang Xiao, Raissa K Mathura, Ben Shofty, Victoria Gates, Joshua Adkinson, Anusha B Allawala, Adrish Anand, Ron Gadot, Ricardo Najera, Hernan G Rey, Sanjay J Mathew, Kelly Bijanki, Garrett Banks, Andrew Watrous, Eleonora Bartoli, Sarah R Heilbronner, Nicole Provenza, Wayne K Goodman, Nader Pouratian, Benjamin Y Hayden, Sameer A Sheth

Staff and Researcher Publications

Research on the neural basis of major depressive disorder suggests that it is fundamentally a disease of cortical disinhibition, where breakdowns of inhibitory neuronal systems lead to diminished emotion regulation and intrusive rumination. Subregions of the prefrontal cortex are thought to be sources of this disinhibition. However, due to limited opportunities for intracranial recordings from humans with major depression, this hypothesis has not been directly tested. Here, we use intracranial recordings from the dorsolateral prefrontal, orbitofrontal, and anterior cingulate cortices from patients with major depression to measure daily fluctuations in self-reported depression symptom severity. Results indicate that directed connectivity within …

Clinically Important Endpoints In Individuals With Leukodystrophy: A Multisite Study, Emma R Kotes, Sarah Woidill, Russell D'Aiello, Amina Khan, Jacob Mccann, Mark Ramos, Francesco Gavazzi, Stephanie Keller, Keith Van Haren, Ali Fatemi, Florian Eichler, Joshua Bonkowsky, Jamie Fraser, Lisa Emrick, Omar Sherbini, Ashley Hackett, Jeilo Gauna, Dandre Amos, Jordan Goodman, Amena Smith Fine, Amanda Nagy, Seungil Lee, Nicole Page, Johanna Schmidt, Amy Pizzino, Kayla Muirhead, Mariko Bennett, Amy Waldman, Justine Shults, Laura Adang, Robert Grundmeier, Adeline Vanderver

Faculty, Staff and Students Publications

Importance: Leukodystrophies are a diverse group of rare disorders that disrupt central myelination. These disorders present with a broad spectrum of neurologic severity and are associated with a range of potential secondary complications, such as scoliosis and failure of independent feeding.

Objective: we explore real-world data of leukodystrophy complications to inform future evidence-based care guidelines across these rare diseases.

Design: In a cross-sectional observational study, we use a leukodystrophy-specific research consortium and the availability of electronic health records (EHR) to capture a cross-section of real-world data.

Setting: Subjects were identified using EHR data from five hospital systems with established expertise …

Inferring Chromosome Segregation Error Stage And Crossover In Trisomic Disorders With Application To Down Syndrome, Zhenhua Li, Wenjian Yang, Gang Wu, Ti-Cheng Chang, Zhongshan Cheng, Meenakshi Devidas, Mary Shago, Andrew J Carroll, Nyla A Heerema, Julie M Gastier-Foster, Brent L Wood, Lauren Sanclemente, Elizabeth A Raetz, Stephen P Hunger, Mignon L Loh, Eleanor Feingold, Tracie C Rosser, Emily G Allen, Stephanie L Sherman, Karen R Rabin, Philip J Lupo, Jun J Yang

Faculty, Staff and Students Publications

Errors in chromosome segregation during gametogenesis, such as nondisjunction (NDJ) errors, have severe consequences in human reproduction, and a better understanding of their etiology is of fundamental interest in genetics. Mapping NDJ errors to meiotic/mitotic stages typically requires proband-parent comparison, limiting its applicability. Herein, we develop Mis-segregation Error Identification through Hidden Markov Models (MeiHMM), a method for inferring NDJ error stage and crossover events based on only genomic data of trisomic probands. Guided by triallelic genotype/haplotype configurations, MeiHMM discerns the allelic origin at each locus, which informs NDJ error during gamete formation, without identifying the parental origin of the trisomy. …

Genome Report: Whole-Genome Assembly Of The Relapsing Fever Tick Ornithodoros Turicata Dugès (Acari: Argasidae), Mackenzie Tietjen, Amanda R Stahlke, David Luecke, Perot Saelao, Sheina B Sim, Scott M Geib, Brian E Scheffler, Anna K Childers, Alexander R Kneubehl, Pete D Teel, Job E Lopez

Faculty, Staff and Students Publications

The soft tick family Argasidae contains vectors of medical and veterinary importance, but few molecular resources are available compared to hard ticks (Ixodidae). One example is Ornithodoros turicata, a recognized vector of Borrelia turicatae, causal agent of human relapsing fever, and a putative vector of African swine fever virus. To address the current lack of molecular resources for the Argasidae, we generated a chromosome-level genome assembly for O. turicata using PacBio sequencing in conjunction with an Illumina Hi-C library. The resulting reference genome has a total of 1.1 Gb in length and was assembled into 10 chromosomes and 368 unplaced …

Single-Cell Profiling Of Bone Metastasis Ecosystems From Multiple Cancer Types Reveals Convergent And Divergent Mechanisms Of Bone Colonization, Fengshuo Liu, Yunfeng Ding, Zhan Xu, Xiaoxin Hao, Tianhong Pan, George Miles, Siyue Wang, Yi-Hsuan Wu, Jun Liu, Igor L Bado, Weijie Zhang, Ling Wu, Yang Gao, Liqun Yu, David G Edwards, Hilda L Chan, Sergio Aguirre, Michael Warren Dieffenbach, Elina Chen, Yichao Shen, Dane Hoffman, Luis Becerra Dominguez, Charlotte Helena Rivas, Xiang Chen, Hai Wang, Zbigniew Gugala, Robert L Satcher, Xiang H-F Zhang

Faculty, Staff and Students Publications

Bone is a common site for metastasis of solid cancers. The diversity of histological and molecular characteristics of bone metastases (BMs) remains poorly studied. Here, we performed single-cell RNA sequencing on 42 BMs from eight cancer types, identifying three distinct ecosystem archetypes, each characterized by an enrichment of specific immune cells: macrophages/osteoclasts, regulatory/exhausted T cells, or monocytes. We validated these archetypes by immunostaining on tissue sections and bioinformatic analysis of bulk RNA sequencing/microarray data from 158 BMs across more than 10 cancer types. Interestingly, we found only a modest correlation between the BM archetypes and the tissues of origin; BMs …

Distinct Systemic Impacts Of Aβ42 And Tau Revealed By Whole-Organism Snrna-Seq, Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Xi Chen, Baiping Wang, Ao-Lin Hsu, Elizabeth Ochoa, Kevin F Bieniek, Shinya Yamamoto, Yi Zhu, Hui Zheng, Yanyan Qi, Hugo J Bellen, Hongjie Li

Faculty, Staff and Students Publications

Both neuronal and peripheral tissues become disrupted in Alzheimer's disease (AD). However, a comprehensive understanding of how AD impacts different tissues across the whole organism is lacking. Using Drosophila, we generated an AD Fly Cell Atlas (AD-FCA) based on whole-organism single-nucleus transcriptomes of 219 cell types from flies expressing AD-associated proteins, either human amyloid-β 42 peptide (Aβ42) or Tau, in neurons. We found that Aβ42 primarily affects the nervous system, including sensory neurons, while Tau induces accelerated aging in peripheral tissues. We identified a neuronal cluster enriched in Aβ42 flies, which has high lactate dehydrogenase (LDH) expression. This LDH-high cluster …

A Single High-Zinc Activation Enhancer Can Control Two Genes Oriented Head-To-Head In Caenorhabditis Elegans, Hanwenheng Liu, Brian Earley, Adelita Mendoza, Patrick Hunt, Sean Teng, Daniel Luke Schneider, Kerry Kornfeld

2020-Current year OA Pubs

Enhancers play critical roles in gene expression, but a full understanding of their complex functions has yet to be defined. The cellular response to excess zinc levels in Caenorhabditis elegans requires the HIZR-1 transcription factor, which binds the high-zinc activation (HZA) enhancer in the promoters of multiple target genes. Cadmium hijacks the excess zinc response by binding and activating HIZR-1. By analyzing the genome-wide transcriptional response to excess zinc and cadmium, we identified two positions in the genome where head-to-head oriented genes are both induced by metals. In both examples, a single predicted HZA enhancer is positioned between the two …

Measles Assessment And Treatment, Bob Underwood, Edward Lyon

Pediatrics in Practice: A CME Podcast

Eddie Lyon, MD, discusses concerns related to an uptick in measles cases, and how community providers can assess, limit exposure and guide patients to remain healthy.

Click here to stream the podcast episode.

First-In-Human Phase I Open-Label Study Of The Anti-Tim-3 Monoclonal Antibody Incagn02390 In Patients With Select Advanced Or Metastatic Solid Tumors, Martin E. Gutierrez, Shou Ching Tang, John D. Powderly, Ani S. Balmanoukian, Paul E. Hoyle, Zhiwan Dong, Lulu Cheng, Xiaohua Gong, John E. Janik, Nawel Bourayou, Omid Hamid

School of Medicine Faculty Publications

Background T-cell immunoglobulin and mucin domain-containing protein-3 (TIM-3) is an immune checkpoint receptor upregulated during anti-programmed death protein-1 (PD-1)/programmed death ligand-1 (PD-L1) immunotherapy for cancer. TIM-3 blockade may improve the antitumor activity of PD-1/PD-L1inhibition. This phase 1 study evaluated INCAGN02390, a novel, fully human Fc-engineered antibody against TIM-3. Methods INCAGN02390 was evaluated by dose escalation at 10-1600 mg infused in 14-day cycles (every 2 weeks [Q2W]) in pretreated patients with select advanced/metastatic immunogenic solid tumors. Objectives included evaluation of safety/tolerability and maximum tolerated dose (MTD) (primary), pharmacokinetics, preliminary antitumor activity, pharmacodynamics, and immunogenicity (secondary). Results Forty patients were enrolled and …

Computational And Imaging Approaches For Precision Characterization Of Bone, Cartilage, And Synovial Biomolecules., Rahul Kumar, Kyle Sporn, Vibhav Prabhakar, Ahab Alnemri, Akshay Khanna, Phani Paladugu, Chirag Gowda, Louis Clarkson, Nasif Zaman, Alireza Tavakkoli

Department of Medicine Faculty Papers

Abstract

Background/Objectives: Degenerative joint diseases (DJDs) involve intricate molecular disruptions within bone, cartilage, and synovial tissues, often preceding overt radiographic changes. These tissues exhibit complex biomolecular architectures and their degeneration leads to microstructural disorganization and inflammation that are challenging to detect with conventional imaging techniques. This review aims to synthesize recent advances in imaging, computational modeling, and sequencing technologies that enable high-resolution, non-invasive characterization of joint tissue health. Methods: We examined advanced modalities including high-resolution MRI (e.g., T1ρ, sodium MRI), quantitative and dual-energy CT (qCT, DECT), and ultrasound elastography, integrating them with radiomics, deep learning, and multi-scale modeling approaches. We …

Engineers Love Trees, Too!, Thomas T. Burke Jr

Stormwater Drainage Conference

No abstract provided.

Callison Promotional Brochure, Callison College

Callison College and School of International Studies

No abstract provided.