Digital Commons Network^™

Protective Effects Of Lactobacillus Rhamnosus Cqfp 202412 On The Brain , Intestines , And Motor Functions Of Antibiotic-Damaged Mice, Cheng Bo, Li Chong, Meng Xianlu

Food and Machinery

［Objective］ To explore the effects of Lactobacillus rhamnosus CQFP 202412 on improving the intestinal barrier,liver,brain neurons,and motor function in mice through its antioxidant and anti -inflammatory activities.［Methods］ A mouse model was established by intraperitoneal injection of a mixed antibiotic solution (neomycin 5 mg/mL,vancomycin 25 mg/mL,amphotericin B 0.1 mg/mL,ampicillin 10 mg/mL,metronidazole 5 mg/mL,and lipopolysaccharide 1.5 μg/mL ),followed by intervention with L.rhamnosus CQFP 202412.After the intervention,weight -loaded swimming time and running exhaustion time were measured,along with liver index and oxidative stress/inflammatory markers in serum and brain tissue.Histopathological changes in the brain were observed by HE staining,and PCR was used to detect the …

Effects Of D-Allulose On Batter Performance And Quality Of Sponge Cakes, Chai Xiya, Li Hua, Wang Xiaoyan, Peng Chao, Li Ruiyao

Food and Machinery

［Objective］ To investigate whether D-allulose can replace sucrose in sponge cakes.［Methods］ D-allulose is used as a sweetener to replace sucrose in the production of sponge cakes.The effects of different substitution levels of D-allulose (0%,10%,20%,30%,40%,50%,based on the weight of sucrose ) on the batter performance and baking quality of the sponge cakes are examined.［Results］］ The addition of D-allulose improves the foaming capacity of egg liquid,the gelatinization temperature,and the viscosity of the batter.As the amount of D-allulose increases,the baking loss rate of the sponge cake significantly decreases from 11.46% to 10.31%,and the specific volume increases from 3.75 to 4.34 mL/g.The color of …

Advances In The Application Of Machine Learning To Food Nutrition And Health, Zhou Xin, Li Dapeng

Food and Machinery

A balanced diet is fundamental to maintaining human health and preventing or reducing the risk of chronic non -communicable diseases.Efficient and accurate analysis of nutritional and functional components in food,followed by the provision of personalized nutritional guidance,is a research hotspot in the field of food nutrition and health.This article reviews the research progress on artificial intelligence technologies,such as machine learning,in the analysis of food nutritional components,functional component analysis and screening,and personalized nutrition,and highlights the pressing issues that need to be addressed in this field.

Effects Of Drying Conditions On The Forming Process , Structure , And Properties Of Konjac Glucomannan-Based Emulsion Films, Liu Yi, Zhu Jingyu, Cheng Yuhang, Yu Xiang, Jiang Fatang

Food and Machinery

［Objective］ To investigate the mechanism by which lipid distribution induced by drying conditions affects the structure and physicochemical properties of konjac glucomannan -based emulsion films.［Methods］ A film -forming emulsion composed of konjac glucomannan,pectin,and basil essential oil (K-P-OG) was prepared.The effects of different drying temperatures (25 ℃,30 ℃,35 ℃,and 40 ℃) on the physicochemical properties of K -P-OG films were examined.The droplet morphology and water distribution during the film -forming process were tracked using confocal laser scanning microscopy (CLSM ),scanning electron microscopy (SEM ),and low -field nuclear magnetic resonance (LF-NMR ).A rheometer was used to analyze the interactions among components within …

Research Progress In The Effects Of Processing Techniques On Catechins In Green Tea, Yuan Fangzheng, Wei Yu, Li Fengling, Du Xuehui, Shi Haichuan, Gao Aiying

Food and Machinery

Catechins are the key substances that endow green tea with a bitter and astringent taste,and the changes in their structures and content have an important effect on the flavor quality of green tea.By collating the current research results related to catechins,this paper summarizes the changes of catechins during the main processing steps including withering,de-enzyming,rolling,and drying of green tea,and explores the main mechanisms of changes in catechins during processing and their effects on the bitterness and astringency of green tea.

Progress In The Application Of Molecularly Imprinted Electrochemical Sensors In The Detection Of Veterinary Drug Residues, Han Yanrong, Chen Yanrong, Wang Chenyu, Kuang Yishan, Zhang Bo

Food and Machinery

Veterinary drugs play a crucial role in ensuring the healthy development of the livestock industry.However,improper or excessive use of veterinary drugs may pose threats to the environment and human health.To achieve effective monitoring of veterinary drug residues,various detection technologies have emerged.Among them,molecularly imprinted electrochemical sensors (MIECSs ) combines the high recognition specificity of molecularly imprinted polymers (MIPs ) with the rapid and sensitive advantages of electrochemical analysis,becoming a powerful tools in the detection of veterinary drug residues and demonstrating great application potential.However,its transition to large -scale application still faces many challenges.This article systematically reviews the progress in the application of …

Conformational Ligand-Directed Targeting Of Calcium-Dependent Receptors In Acute Trauma, Renata Pasqualini, Christopher Markosian, Daniela I Staquicini, Andrey S Dobroff, Esteban Dodero-Rojas, Paul C Whitford, E Magda Barbu, Julianna K Bronk, Marina Cardó-Vila, Dawn R Christianson, Emmanuel Dias-Neto, Wouter H P Driessen, Liliana Guzman-Rojas, Serena Marchiò, Diana N Nunes, Francislon S De Oliveira, Michael G Ozawa, Bettina Proneth, Roberto Rangel, Tracey L Smith, Glauco R Souza, Fernanda I Staquicini, Fenny H F Tang, Wallace B Baze, João C Setubal, John W Burns, Michael A Dubick, Juri G Gelovani, Andriy I Batchinsky, Jon E Mogford, Charles E Wade, John B Holcomb, Stephen K Burley, José N Onuchic, Wadih Arap

Faculty, Staff and Student Publications

Background: Trauma is a leading cause of mortality, but injury-specific molecular targets remain largely unknown. We hypothesized that distinctive yet unrecognized tissue targets accessible to circulating ligands might emerge during trauma, thereby underscoring a trauma-related proteome.

Methods: We screened a peptide library to discover targets in a porcine model of major trauma: compound femur fracture with hemorrhagic shock. Bioinformatics yielded conserved motifs, and candidate receptors were affinity purified. In silico and in vitro approaches served to investigate possible associations between candidate receptors and calcium, a major component of skeletal muscle and bone. In vivo homing and molecular imaging (PET/MRI and …

Vitamin K And Women's Health: A Review, Sharifa Alblooshi

All Works

Vitamin K is a fat-soluble vitamin essential in various physiological functions such as blood coagulation, bone metabolism, cardiovascular health, glucose regulation, immune function, neuroprotection, and vascular health. In this narrative review, studies from databases including PubMed, Google Scholar, Scopus, and the institutional database of Zayed University were selected. The role of vitamin K in women's health, with a focus on osteoporosis, postmenopausal health, cardiovascular health, diabetes, cancer, kidney health, brain health, vascular health, and pregnancy were explored. The role of vitamin K in activating vitamin K-dependent proteins is essential for many of its functions. Vitamin K-dependent proteins such as osteocalcin …

Rapid High-Sensitivity Detection Of Antibodies To Trypanosoma Cruzi With A Recombinant Tc24 Antigen-Based Magneto-Immunoassay: A Pilot Study, Kavya L Singampalli, Bin Zhan, Rojelio Mejia, Peter B Lillehoj

Faculty, Staff and Students Publications

The diagnosis of chronic Chagas disease is challenging due to the wide genetic diversity of Trypanosoma cruzi, the causative agent of Chagas disease, and low levels of parasitemia, resulting in low sensitivity and accuracy with existing diagnostics. We report a magneto-immunoassay that employs dually labeled magnetic beads incorporating a recombinant Tc24 antigen, which is homologous across multiple discrete typing units of T cruzi. In this pilot study, 102 serum samples from 7 endemic countries were tested by this magneto-immunoassay, revealing its ability to distinguish Chagas-positive from Chagas-negative cases more accurately and faster than a standard Tc24-based immunoassay.

Impact Of Sanitation System Types On Residential And Environmental Presence Of Human Waste And Parasites In Alabama, Brandon Hunter, Catherine Coleman Flowers, Rojelio Mejia, Marc Arnold Deshusses

Faculty, Staff and Students Publications

Lowndes County is a predominantly Black rural county in Alabama, in the United States, which has a historical and current legacy of racial discrimination, creating inequitable infrastructure access and adverse health impacts. Over 80% rely on on-site sanitation infrastructure and most are failing. A community assessment of exposure to untreated sewage was conducted using samples from residential drinking water, surface swabs, and soil combined with environmental water and soil samples using culture-based and quantitative polymerase chain reaction (qPCR) methods. Testing varied slightly across samples, due to difficulty of access or availability. Of 43 households, 68% and 55% of houses had …

Oral Dosing Of The Nucleoside Analog Obeldesivir Is Efficacious Against Rsv Infection In African Green Monkeys, Jared Pitts, J Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicholas C Riola, Arya Vijjapurapu, Meghan S Vermillion, Stacey Eng, Christopher Richards, Dong Han, Jason K Perry, Subhra Chaudhuri, Szu-Wen Liu, Clarissa Martinez, Nadine Peinovich, Kai-Hui Sun, Arthur Cai, Ross Martin, Jasmine Moshiri, Charlotte Hedskog, Darius Babusis, Dustin S Siegel, Rao Kalla, Vasanthi Avadhanula, Pedro A Piedra, Kim Stobbelaar, Peter L Delputte, Caleb Marceau, Roberto Mateo, Evguenia Maiorova, Hongmei Mo, Raju Subramanian, Richard L Mackman, Tomas Cihlar, Simon P Fletcher, John P Bilello

Faculty, Staff and Students Publications

Respiratory syncytial virus (RSV) is a significant cause of morbidity and mortality in high-risk populations. Although prophylactic options are available, there are no effective oral therapeutics for RSV infection. Obeldesivir (ODV) is an orally bioavailable prodrug of the nucleoside analog GS-441524, which is converted intracellularly to its active nucleoside triphosphate and inhibits the RSV RNA polymerase. Here we report the potent antiviral activity of ODV against geographically and temporally diverse RSV A and B clinical isolates (EC50: 0.20–0.66 μM). Resistance selection studies with ODV and GS-441524 against RSV identify a single amino acid substitution, I777L, in the L polymerase with …

The Current And Future Burden Of Long Covid In The United States, Sarah M Bartsch, Kevin L Chin, Ulrich Strych, Danielle C John, Tej D Shah, Maria Elena Bottazzi, Kelly J O'Shea, Mckaylee Robertson, Colleen Weatherwax, Jessie Heneghan, Marie F Martinez, Allan Ciciriello, Sarah Kulkarni, Kavya Velmurugan, Alexis Dibbs, Sheryl A Scannell, Yanhan Shen, Denis Nash, Peter J Hotez, Bruce Y Lee

Faculty, Staff and Students Publications

Background: Long coronavirus disease (COVID), which affects an estimated 44.69-48.04 million people in the United States, is an ongoing public health concern that will persist as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread.

Methods: We developed a computational simulation model representing the clinical course, health effects, and associated costs of a person with long COVID.

Results: Simulations show that the average total cost of a long COVID case can range from $5084-$11 646 (assuming symptoms only last 1 year) with 92.5%-95.2% of these costs being productivity losses. Therefore, the current number of long COVID cases could cost …

Src/Fn1 Pathway Activation Drives Tumor Cell Cluster Formation And Metastasis In Lung Cancer: A Promising Therapeutic Target, Zujun Que, Zhichao Xi, Dan Qi, Rongchen Dai, Yang Li, Mengfan Liu, Bin Luo, Jiajun Liu, Pan Yu, Yun Yang, Erxi Wu, Hongxi Xu, Jianhui Tian

Children’s Nutrition Research Center Staff Publications

Lung cancer remains the leading cause of cancer-related death globally, with metastasis driven by circulating tumor cells (CTCs)-particularly clusters-being a major treatment challenge. Despite their critical role, the biological differences between single CTCs and CTC clusters remain unclear. Here, we comprehensively compared their behavioral, transcriptomic, and proteomic profiles in lung cancer models. Compared with single cells, CTC clusters present enhanced metastatic potential, greater survival in the bloodstream and increased resistance to microenvironment. Mechanistically, the Src/FN1 pathway is centrally activated in clusters, promoting intercellular cohesion and protecting against immune clearance and stress in circulation. Pharmacological inhibition of Src with the clinical …

Re: Approval Letter For The Response To Comment Letter And The Butte Priority Soils Operable Unit (Bpsou) Draft 2024 Butte Reclamation Evaluation System (Bres) Corrective Action Plans For Reclaimed Sites (Both Dated June 6, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Comment Letter For 2024 Annual Operations And Maintenance Report Butte Reclamation Evaluation System (Bres) Annual Summary Report For Work Completed In Quadrant 4 (Dated May 1, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Comment Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final Unreclaimed (Ur) Sites Ur-13 Site Evaluation Summary Report (Sesr) (November 1, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Combination Hyaluronic Acid And Multipotent Stromal Cells Fails To Improve Rat Knee Oa Outcomes Compared To Cells Alone, Kennedy Michele Davis, Megan Hamilton, Donald Muathe, Aldyn Wildey, Stephen Harrington, Douglas Bittel, Michael Filla, Lisa Stehno-Bittel

Faculty and Staff Publications

Introduction: Multipotent Stromal Cells (MSCs) are utilized as therapeutic agents for addressing musculoskeletal conditions, including knee osteoarthritis (OA). However, major challenges in the clinical application include maintenance of the cells in the joint capsule. Hyaluronic acid (HA) is endogenous in synovial joints and commercially available as a joint lubricant. We tested the hypothesis that delivery of MSCs in HA into an OA rat knee model could improve outcomes.

Methods: Rat bone marrow MSCs were suspended in a commercially available HA paste, and cell viability measured with live/dead stains. Biomarkers for MSC chondrogenesis and osteogenesis were monitored with PCR. MSCs with …

Savings Associated With Bundled Payments For Outpatient Spine Surgery Among Medicare Beneficiaries, Austin S. Kilaru, Grace Y. Ng, Erkuan Wang, Erin Huang, Aidan P. Crowley, Jingsan Zhu, Joshua M. Liao, Said A. Ibrahim, Torrey Shirk, Deborah S. Cousins, Neil R. Malhotra, Amol S. Navathe

Department of Medicine Faculty Papers

IMPORTANCE: Few value-based payment programs have targeted outpatient surgery, although these procedures comprise most surgeries performed in hospitals. In 2018, the Centers for Medicare and Medicaid Services introduced Bundled Payments for Care Improvement Advanced (BPCI Advanced), the first episode-based payment model to include an outpatient surgical condition-spine surgery. It is not known whether bundled payments reduce spending or improve quality for outpatient surgery, despite plans to expand outpatient episodes in future models.

OBJECTIVE: To determine whether hospital participation in the first year of BPCI Advanced for outpatient and inpatient spine surgery (back and neck except spinal fusion procedures [BNESF]) was …

A Learning Plan On The Understanding Of Abo Blood Group Compatibility, Ermor Francisco-Martizano

Annual Research Congress for High School and Elementary Teachers, Researchers, and Scholars (ARCHERS)

This learning plan is designed to gain a better understanding of ABO blood group compatibility, including how blood types are determined, their importance, and how they affect blood transfusions and organ transplants. The following objectives outline the specific objectives to be accomplished by the end of the lesson:

A. identify the different blood types and their characteristics;

B. understand the importance of ABO blood group compatibility in blood transfusions and organ transplants;

C. enumerate the consequences of incompatible blood transfusions and organ transplants;

D. demonstrate blood typing techniques to know ABO blood compatibility.

The goals above are aligned with the …

Savoring The Seaweeds: Health And Sustainability Through Creole Foods, Roxanna Belleau

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Incorporating kelp into American diets offers a promising avenue for enhancing nutrition and environmental sustainability. Despite its nutritional richness and ecological benefits as a "superfood" and carbon sink, cultural resistance presents a barrier to its widespread acceptance. This study delves into kelp's nutritional content and ecological advantages, exploring its potential to reshape dietary habits. Drawing insights from interviews and surveys, cultural norms emerge as a significant obstacle to kelp's integration into American cuisine. Strategies inspired by successful culinary adaptations, such as creole dishes, are proposed to navigate these challenges and shift societal perceptions. Furthermore, integrating kelp into familiar American foods …

The Tax Adviser, Volume 10, Number 8, August 1979, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

Estate Planning: Understanding The Use And Taxation Of Powers Of Appointment, Gary R. Stout

Tax Adviser

No abstract provided.

New Approaches To Media Education

Communication Research Trends

There is increasing consensus among educators around the world that some form of education for the use of the public media - especially television - should be an integral part of the primary and secondary school education.

Teachers are daily experiencing the fact that one of the major cultural influences forming the imagination of their students is the often long hours watching television. Sometimes television is a more important 'educational experience' than the school. Too often, however, the school, family life and the· television set are three mutually antagonistic or indifferent poles that leave young people drifting in a no …

Critical Reviews Of Advertising

Communication Research Trends

In the late 1950s and early 1960s a series of very influential thinkers began a strong movement of criticism of advertising. This questioning of advertising led to a deeper questioning of the 'cult of consumerism' which advertising propagates.

Vance Packard in his popular book, The Hidden Persuaders (1956) attacked advertising for using the techniques of depth psychology to raise 'subliminal anxieties' and manipulate desires for alcohol, cigarettes and other consumer items. John Kenneth Galbraith, in The Affluent Society (1958) pointed out that advertising was encouraging a wasteful consumerism which allowed a small portion of the world's people to use up …

Spotlight, Robert F. Manning

Tax Adviser

No abstract provided.

Subject Index, 12 Months Ended June 1979, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Spotlight, Robert F. Manning

Tax Adviser

No abstract provided.

Insurance Companies And The Income Tax: Legislative Developments, Gordon O. Pehrson, Carolyn P. Chiechi, John T. Adney

Tax Adviser

No abstract provided.

Tax Reserves For Losses On Loans Of Banks: The Need For Reappraisal A, Sally Morrow Jones, Ronald P. Meier

Tax Adviser

No abstract provided.