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Anxiety's Impact On Autism Spectrum Disorder Symtomology: An Investigation Into The Relationship Between Two Comorbities, Michaela Brown

LSU Doctoral Dissertations

Autism spectrum disorder (ASD) has been found to be frequently comorbid with many medical and psychological disorders, one of which is anxiety disorders. Research has shown that, when anxiety is present within ASD, various areas of the child’s functioning may be impacted, such as ASD symptom severity, emotional regulation skills, adaptability, social skills and daily living skills. The current study aimed to investigate this relationship of anxiety and ASD. First, within a sample of children and adolescents with ASD, the magnitude of the correlation between specific ASD symptoms parent-reported anxiety was compared to determine if certain ASD symptoms were more …

Cryo-Em Structures Of A Pentameric Ligand-Gated Ion Channel In Liposomes, Vikram Dalal, Brandon K Tan, Hanrui Xu, Wayland W L Cheng

2020-Current year OA Pubs

Detergents and lipid nanodiscs affect the cryo-EM structures of pentameric ligand-gated ion channels (pLGICs) including ELIC. To determine the structure of a pLGIC in a membrane environment that supports ion channel function, we performed single particle cryo-EM of ELIC in liposomes. ELIC activation and desensitization were confirmed in liposomes with a stopped-flow thallium flux assay. Using WT ELIC and a non-desensitizing mutant (ELIC5), we captured resting, activated, and desensitized structures at high resolution. In the desensitized structure, the ion conduction pore has a constriction at the 9' leucine of the pore-lining M2 helix, indicating that 9' is the desensitization gate …

V2b Neurons Act Via Multiple Targets To Produce In Phase Inhibition During Locomotion, Mohini Sengupta, Alaina Bertram, Shuyu Iris Zhu, Geoffrey J Goodhill, Martha W Bagnall

2020-Current year OA Pubs

Spinal interneurons shape motor neuron activity. Gata3

Integrating Digital Archives And Scholarship: Raising Awareness Of Library Historical Collections, Alice W. Sherwood

Library Staff Publications

The Texas Medical Center (TMC) is home to the largest concentration of medical professionals and experts anywhere in the world. Collectively, the Texas Medical Center is the largest employer in Houston and the 8th largest business district in the United States. The TMC includes 50 medicine-related institutions, including 21 hospitals and two specialty institutions, two medical schools, six nursing schools, and schools of dentistry, public health, and pharmacy. The TMC Library plays a vital role for the institutions inhabiting the 2.10 square mile campus that is the TMC. The Texas Medical Center Library has been around since 1915, way before …

False Starts & Finish Lines: Youth Sports, Coaching, & The Crisis Of The American Dream, John S. Lammert Jr

Master's Theses

False Starts & Finish Lines: Youth Sports, Coaching, & the Crisis of the American Dream examines how the American youth sports system reflects, reproduces, and at times resists the evolving contradictions of the American Dream. Drawing on a comparative analysis of institutional documents from public high schools, travel clubs, and recreational leagues, this thesis interrogates how youth sports have shifted from inclusive spaces of play and character-building to stratified marketplaces governed by the Athletic Industrial Complex (AIC). It argues that rising costs, performance pressures, and privatized structures have transformed access to sport—and, by extension, to the Dream itself—into a function …

For Every Right A Remedy: Providing A Private Right Of Action Under The Church Amendments, Brad Grisenti

BYU Law Review

In 1973, Congress responded to the U.S. Supreme Court’s Roe v. Wade decision by passing legislation known as the “Church Amendments.” The Church Amendments were designed to protect healthcare workers from being compelled by their employers to perform or participate in abortion or sterilization procedures that conflict with their moral and religious beliefs. However, the Church Amendments suffer from an enforcement problem, largely due to Congress’s failure to explicitly provide a private right of action in the text of the statute. And thus far, courts have consistently refrained from interpreting it as containing an implied private right of action. Without …

Redefining Child Pornography In An Age Of Technological Advancement: The Concept Of Avoidable Harm, Debra D. Burke, Christopher N. Doval

Washington Journal of Law, Technology & Arts

In 2020, Netflix released on its streaming service the movie Cuties, a coming-of-age story about an 11-year-old Senegalese immigrant who joined a dance group. The film is a commentary against the hyper-sexualization of children and the pressure young girls face from social media and society and received a director’s award at the Sundance Film Festival. Its release, however, kicked off a culture war, prompting a movement to cancel Netflix subscriptions in response to the film’s sexually provocative imagery of young girls. The movie’s award-winning director defended the film’s message, explaining that the film was her own story, struggling as a …

Stolen Humanity On Display: Lacking Legislation For Human Remains In U.S. Museums, Sarah M. Fassio

Washington Journal of Law, Technology & Arts

In museums across the United States, displays of human remains are not rarities. Yet few attendees stop to consider the provenance behind those once-living parts of our ancestors. To do so, one would have to contend with an unpleasant history rife with scientific racism and graverobbing for the personal collections of society’s upper crust. Considering the origins of such displays reveals that the labels and names attached to human remains in museums often serve more to alienate them from their humanity than they do to connect or contextualize.

Legal regulations pertaining to displayed human remains are piecemeal. There are federal …

Precise Operations, Imprecise Laws: How Nebulous Laws Wreak Havoc In Outer Space, Matthew H. Ormsbee, Harine Raaj

Washington Journal of Law, Technology & Arts

As space operations advance with unprecedented precision, the laws governing these activities remain outdated, vague, and incapable of addressing contemporary challenges. The Outer Space Treaty (OST) and the Liability Convention, drafted in the Cold War era, fail to adequately define fundamental terms such as damage, fault, and compensation. This lack of legal precision creates significant liability gaps, particularly as space debris, mega-constellations, and private-sector actors reshape the space landscape. This article explores how these ambiguities hinder legal predictability and fair compensation for victims of space-related harm. By analyzing real-world space incidents, including the Cosmos 954 reentry, the Iridium-Cosmos collision, and …

Nitric Oxide Does Not Improve Liver Mitochondrial Function 48 Hours After Cecal Ligation And Perforation In Experimental Sepsis, Pierre Eyenga, Shey-Shing Sheu

Center for Translational Medicine Faculty Papers

Nitric oxide (NO) has a dual effect on mitochondria. Incubating liver mitochondria with NO improves oxidative phosphorylation (OXPHOS) efficiency by decreasing state 4 respiration more than ATP synthesis and preventing mitochondrial permeability transition pore (mPTP) opening. We evaluated the effect of L-arginine (L-arg), an NO donor, on isolated liver mitochondrial respiration and mPTP in sepsis. Male mice were subjected to cecal ligation and perforation (CLP) with saline resuscitation or sham. After 8, 24, and 48 h, with and without L-arg, we measured isolated liver mitochondrial respiration and cytochrome c oxidase (COX) activity using polarographic methods and calcium retention capacity (CRC) …

Midweek Memo, Georgia Southern University

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Impacts Of Artificial Habitat Structures On Overwinter Fish Survival And Fish Presence In South-Central Nebraska, Logan Dietrich

Biology Theses, Dissertations, and Student Creative Activity

Artificial lentic systems, such as borrow pits, often lack structural complexity due to construction practices and steep bathymetry, limiting features like vegetation and woody debris essential for fish communities. To address this, artificial structures made of materials such as polyvinyl chloride are increasingly used by state and federal agencies to supplement habitat. However, little information is known about the impact these structures have on fish communities. Thus, the objectives of this study were to examine the influence of Georgia cubes in borrow pit impoundments on overwinter survival of sub-stock and ≥ stock Bluegill (Lepomis macrochirus) and Largemouth Bass …

Veterinary Drug Residue Regulations In Major U.S. Export Markets, Elliott James Dennis, Akinbode Okunola

Cornhusker Economics

Trade agreements shape the global agricultural trade landscape, encompassing both tariff and non-tariff measures. Among the latter, sanitary and phytosanitary (SPS) measures such as maximum residue limits (MRLs) are gaining attention. As trade tensions escalate, there is growing concern that countries could use SPS measures as a tool of retaliation in international agricultural markets, as they are often a focal point in trade negotiations (Disdier and Marette, 2010; Disdier and van Tongeren 2010; Grant et al., 2015).

Anesthetic Management For Delivery In Parturients With Heart Disease: A Narrative Review, Shahab Ahmadzadeh, Drake P. Duplechin, Paris D. Bailey, Dillon T. Duplechan, Alexia J. Enache, Peyton Moore, Sahar Shekoohi

School of Medicine Faculty Publications

Cardiac disease remains a leading cause of maternal morbidity and mortality, particularly in developed countries where improved survival has increased the number of pregnant patients with congenital heart disease. The physiological changes of pregnancy, such as increased blood volume, cardiac output, and hypercoagulability, can exacerbate preexisting cardiac conditions, posing significant anesthetic challenges during cesarean delivery. This review outlines anesthetic strategies for parturients with structural or functional cardiac disease, emphasizing individualized, multidisciplinary care. We examine general and regional anesthesia approaches, intraoperative monitoring, and hemodynamic goals, including fluid balance, venous return optimization, and myocardial oxygen demand reduction. Preoperative risk stratification and coordination …

Vibration-Based Detection For The Monitoring Of Neonatal Bcpap Respiratory Support To Minimize Duration Of Disconnections, Kaitlyn G. Calabresi, Meera R. Bhat, Lavinia L. Kong, Eli J. Foster, Jonathan Wang, Sangeeta Koilada, Angela Mak, Aastha Kapadia, Niam Mohseni, W. Keith Leung, Suneetha Desiraju, Constanza Miranda

School of Medicine Faculty Publications

Bubble continuous positive airway pressure (bCPAP) is a minimally invasive respiratory support for neonates experiencing respiratory distress syndrome (RDS). It exerts continuous, oscillatory air pressure to encourage lung function and development. Neonates’ movement may cause disconnections at the nasal interface. These disconnections are characterized by the cessation of bubbling at the bCPAP respiratory circuit output and frequently go unnoticed until hypoxia develops. Common Neonatal Intensive Care Unit (NICU) bCPAP systems lack a built-in alarm or accessory device to monitor for disconnections. As a result, nursing personnel must exercise extreme caution utilizing current bCPAP procedure. If a neonate is disconnected, it …

Public Sector Employment In Mountain West Cities, 2019, Olivia K. Cheche, William E. Brown Jr.

Economic Development & Workforce

This fact sheet presents data on public sector employment in 16 cities within the Mountain West states of Arizona, Colorado, Nevada, and New Mexico. The Urban Institute’s “Public Sector Employment and Its Role in Local Economic Development” report provides data on publicly driven jobs in the 100 largest U.S. cities as of 2019. This fact sheet focuses on city-level data from the largest cities in the Mountain West.

Human Development, Inequality, And Their Associations With Brain Structure Across 29 Countries, Vicente Medel, Luz M. Alliende, Richard Bethlehem, Jakob Seidlitz, Grace Ringlein, Celso Arango, Aurina Arnatkevičiūtė, Laila Asmal, Mark Bellgrove, Anderson M. Winkler

Human Genetics Publications

Background: The macro-social and environmental conditions in which people live, such as the level of a country’s development or inequality, are associated with brain-related disorders. However, the relationship between these systemic environmental factors and the brain remains unclear. We here aimed to determine the association between the level of development and inequality of a country and the brain structure of healthy adults.

Methods: We conducted a cross-sectional study pooling brain imaging (T1-based) data from 145 magnetic resonance imaging (MRI) studies in 7,962 healthy adults (4,110 women) in 29 different countries. We used a meta-regression approach to relate the brain structure …

Religious Freedom As Freedom, Helen M. Alvaré

BYU Law Review

In recent decades, the exercise of religious freedom is increasingly associated with oppression. This is not only due to the disagreement between religions and some governments concerning sexual expression matters—contraception, abortion, same-sex relations, and transgender identity—but is also due to diverging convictions about the substance and sources of freedom. This Article will examine a current and highly visible set of convictions about the contents of human freedom, which together suggest that a thriving religious witness threatens freedom itself. These convictions often surface in the context of laws touching upon sexual expression. It will then contrast these convictions with those found …

Full Issue

BYU Law Review

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Agreeing To Disagree: Abortion Jurisprudence In Jewish And Islamic Law, Rabea Benhalim

BYU Law Review

This Article challenges the prevailing perception that religious people and religious legal traditions are anti-abortion. While this may be true within certain conservative Christian perspectives, this perception is an inaccurate representation of Jewish and Muslim Americans and their respective legal traditions. Both the Jewish and Islamic legal traditions offer a range of nuanced positions on abortion. Furthermore, diverse opinions of Jewish and Islamic abortion jurisprudence inform a variety of topics salient to the current legal debate in the United States. This range of opinions includes strict limitations on abortion, circumstantial legality, and general permissibility. Scholars from both traditions engaged in …

Wither, Religious Liberty, Amanda Harmon Cooley

BYU Law Review

During the oft-deemed Constitutional Revolution of 1937, the U.S. Supreme Court effected a significant sea-change in its substantive due process liberty analysis. In West Coast Hotel v. Parrish, the Court held that the Due Process Clause’s liberty provision does not protect absolute freedom of contract, signaling the demise of the Lochner era. Almost a century later, the current Supreme Court’s supermajority bloc is now infamous for its own seismic shift in liberty analysis. This Court’s incontrovertible Constitutional Revolution of 2022 was not limited to only substantive due process, which the Court shifted with its decision in Dobbs v. Jackson Women’s …

Two Concepts Of Judicial Deference To Religious Claims, Chagai Schlesinger

BYU Law Review

Religious exemptions from general laws are everywhere. The U.S. Supreme Court is expanding its exemption doctrine, systemically preferring religious needs over conflicting considerations. This ignites an ongoing debate between those celebrating religious liberties and those fearing their societal costs. Assessing this judicial trend, as this Article highlights, requires noticing how it is facilitated by a broad deferential approach to religious claims, refraining from evaluating their content.

This Article argues that this broad expression of judicial deference is analytically flawed and normatively implausible. The problem lies in the failure to distinguish between two types of religious claims when deferring to them: …

The Social Psychology Of Religious Liberty Depolarization, Asma T. Uddin

BYU Law Review

This Article examines the U.S. Supreme Court's approach to cases involving religious liberty and LGBTQ+ rights through the lens of social psychology. As Americans increasingly sort into opposing “mega- identities” defined by political, racial, and religious traits, religious liberty has become a deeply polarized issue, with traditional Christians and LGBTQ+ advocates often positioned as adversaries in a zero-sum conflict. Against this backdrop, the Article argues that the Roberts Court has employed social psychological techniques—specifically “aporia” (acknowledging complexity) and “affirmation” (validating diverse viewpoints)—to de-escalate this cultural tension. By analyzing key decisions in Masterpiece Cakeshop v. Colorado Civil Rights Commission, Fulton v. …

A Multidimensional Perspective Of Patterns Of Functioning And Well-Being, Lendi Nicole Joy

USF Tampa Graduate Theses and Dissertations

The Center for Behavioral Health Statistics and Quality estimates that 79.4% of U.S. adults will remain free from mental illness each year, but this does not necessarily mean they will enjoy positive psychological health and well-being. Well-being has been associated with positive outcomes such as greater health, longevity, work productivity, and increased social engagement. Thus, it is important for researchers to understand factors contributing to the development of well-being and optimal functioning. The current study used latent profile analysis to classify individuals based on their levels of well-being at ages 23 to 26 years and explored functioning indexes assessed when …

Assessment Of Decorin Level And Some Biochemical Parameters In Iraqi Patients With Diabetic Nephropathy, Zahraa M. Ismail, Falah S. Al-Fartusie, Ahmed H. Ismail, Noor T. Tahir

Baghdad Science Journal

Diabetic nephropathy (DN) is a serious kidney complication that can occur in individuals with diabetes; around 20% to 30% of individuals with Type 2 diabetes (T2D) develop diabetic nephropathy (DN), which is a persistent microvascular complication. The DN is often considered the leading contributor to end-stage renal failure. This study aimed to assess decorin levels and their correlation with various biochemical variables among three different groups: 40 patients with T2DM nephropathy (G1), 40 patients with T2DM without nephropathy (G2), and a healthy control group (G3). The study included a total of 120 participants, divided into three groups T2DM with DN …

Studying The Level Of Carboxy-Terminal Cross Link Telo Peptide Type-1 Collagen And Human Cartilage Glycoprotein In Sera Of Iraqi Patients With Knee Osteoarthritis, Asmaa Rafea Mohamed, Bushra F. Hasan

Baghdad Science Journal

Knee osteoarthritis (KOA), commonly known as degenerative joint disease, is frequently brought on by wear-and-tear articular cartilage loss that occurs over time and most often affects the elderly. Since cartilage is the main element that breaks down when OA occurs, its chemical components can be exploited to develop a sensitive biomarker to identify the beginning and progression of OA disease. The study aimed to evaluate and assess the alteration in the serum level of collagen type I C-telopeptide (CTX-1), and human cartilage glycoprotein (YKL-40) in serum samples obtained from (81) patients diagnosed with Knee Osteoarthritis who were hospitalized in Baghdad …

Strength And Anti-Wettability Enhancement Of Double Layer Pvdf/Pmma Nanofibers Membrane By Embedding Sio2 Nanoparticles, Nawras N. Safi, Basma I. Waisi

Baghdad Science Journal

For the desalination of brine and seawater, membrane distillation (MD) is a desirable treatment method. Because of their high permeability and rejection, electrospun nanofiber membranes (ENMs) are becoming more popular in (MD) applications. Due to their unique features, superhydrophobic nanofibers have garnered much attention from scientists working to perfect high-efficiency MD membranes. In this work, a completely novel double-layer design approach for superhydrophobic membranes was proposed for water desalination using Direct Contact Membrane Distillation (DCMD). A double-layer of nonwoven nanofiber membranes was created using hydrophobic polymers via an electrospinning technique. Electrospinning created a double-layer membrane of nonwoven nanofibers utilizing hydrophobic …

Synthesis Of Salicylaldehyde Derivatives And Evaluating Its Antimicrobial, Antifungal, And Anticorrosion Activities, Ibrahim Mamedov, Ali Khalilov

Baghdad Science Journal

Chalcones are natural, unsaturated aromatic ketones used in organic synthesis and medicine. Nevertheless, obtaining synthetic analogs and studying their reactions remains relevant. Unsaturated aromatic ketones are important substrates for synthesizing various heterocyclic compounds. The new chalcone, dihydropyrazole derivatives were synthesized based on 2-hydroxy-5-phenyldiazenyl benzaldehyde, and their structures were studied by NMR. Many metal structures fail each year due to harsh conditions, causing significant damage to the global economy. To overcome this problem, chemists are constantly researching and developing new corrosion inhibitors. The compounds under test contain nitrogen, oxygen, and sulfur atoms, which can be coordinated with metals. These types of …

Childhood Skeletal Lesions Common In Prehistory Are Present In Living Forager-Farmers And Predict Adult Markers Of Immune Function, Amy S. Anderson, Aaron Blackwell, M. Linda Sutherland, Thomas Kraft, James Sutherland, Bret Beheim, Daniel K. Cummings, Suhail Ghafoor, Paul L. Hooper, Daniel Eid Rodriguez, Andrei Irimia, Margaret Gatz, Wendy Mack, Chris Rowan, Michael Miyamoto, Kenneth Buetow, Caleb Finch, L. Samuel Wann, Adel Allam, Randall C. Thompson, Gregory Thomas, Hillard Kaplan, Jonathan Stieglitz, Benjamin Trumble, Michael D. Gurven

ESI Publications

Porous cranial lesions (cribra cranii and cribra orbitalia) are widely used by archaeologists as skeletal markers of poor child health. However, their use has not been validated with systematic data from contemporary populations, where there has been little evidence of these lesions or their health relevance. Using 375 in vivo computed tomography scans from a cohort-representative sample of adults aged 40+ years from the Bolivian Amazon, among food-limited, high-mortality forager-farmers, we identified cribra cranii on 46 (12.3%) and cribra orbitalia on 23 (6%). Cribra orbitalia was associated with several hallmarks of compromised immune function, including fewer B cells, fewer naïve …

Development And Extensive Sequencing Of A Broadly-Consented Genome In A Bottle Matched Tumor-Normal Pair, Jennifer H Mcdaniel, Vaidehi Patel, Nathan D Olson, Hua-Jun He, Zhiyong He, Kenneth D Cole, Alexander A Gooden, Anthony Schmitt, Kristin Sikkink, Fritz J Sedlazeck, Harsha Doddapaneni, Shalini N Jhangiani, Donna M Muzny, Marie-Claude Gingras, Heer Mehta, Sairam Behera, Luis F Paulin, Alex R Hastie, Hung-Chun Yu, Victor Weigman, Alison Rojas, Katie Kennedy, Jamie Remington, Isai Salas-González, Mitch Sudkamp, Kelly Wiseman, Bryan R Lajoie, Shawn Levy, Miten Jain, Stuart Akeson, Giuseppe Narzisi, Zoe Steinsnyder, Catherine Reeves, Jennifer Shelton, Sarah B Kingan, Christine Lambert, Primo Baybayan, Aaron M Wenger, Ian J Mclaughlin, Aaron Adamson, Christopher Kingsley, Melanie Wescott, Young Kim, Benedict Paten, Jimin Park, Ivo Violich, Karen H Miga, Joshua Gardner, Brandy Mcnulty, Gail L Rosen, Rajiv Mccoy, Francesco Brundu, Erfan Sayyari, Konrad Scheffler, Sean Truong, Severine Catreux, Lesley Chapman Hannah, Doron Lipson, Hila Benjamin, Nika Iremadze, Ilya Soifer, Gat Krieger, Stephen Eacker, Mary Wood, Erin Cross, Greg Husar, Stephen Gross, Michael Vernich, Mikhail Kolmogorov, Tanveer Ahmad, Ayse G Keskus, Asher Bryant, Francoise Thibaud-Nissen, Jonathan Trow, Jacqueline Proszynski, Jeremy Wain Hirschberg, Krista Ryon, Christopher E Mason, Mital S Bhakta, J Zachary Sanborn, Elizabeth M Munding, Justin Wagner, Chunlin Xiao, Andrew S Liss, Justin M Zook

Faculty, Staff and Students Publications

The Genome in a Bottle Consortium (GIAB), hosted by the National Institute of Standards and Technology (NIST), is developing new matched tumor-normal samples, the first explicitly consented for public dissemination of genomic data and cell lines. Here, we describe a comprehensive genomic dataset from the first individual, HG008, including DNA from an adherent, epithelial-like pancreatic ductal adenocarcinoma (PDAC) tumor cell line and matched normal cells from duodenal and pancreatic tissues. Data for the tumor-normal matched samples comes from seventeen distinct state-of-the-art whole genome measurement technologies, including high depth short and long-read bulk whole genome sequencing (WGS), single cell WGS, Hi-C, …