Digital Commons Network^™

Let's Doff: A Gown Conservation Strategy For Multidrug-Resistant Organism Colonization During The Covid-19 Pandemic And Beyond, Kelsey L Rowe, Josephine Fox, Carole Leone, Lydia J Grimes, Kenneth Whalen, David K Warren, Jonas Marschall

2020-Current year OA Pubs

A COVID-19 pandemic gown conservation strategy for methicillin-resistant

Understanding User Behaviors: Impact Of A 28-Day Intervention On Screen Time And Problematic Internet Use, Cade T. Campigli

Master's Theses

This thesis examines a 28-day self-monitoring intervention to reduce problematic internet use among undergraduate Instagram users. A quasi-experimental factorial mixed design with a repeated measures component was used, with participants split into an experimental group (daily Instagram screen time logging) and a control group (reporting Instagram interactions). Problematic Internet use was measured using the Generalized Problematic Internet Use Scale 2 (GPIUS2). Results showed no reduction in problematic internet use in the experimental group compared to the control, nor a correlation between screen time changes and problematic internet use. However, the experimental group showed a modest decrease in mean screen time …

Selenium Nanoparticles Synthesized By Pulsed Laser Ablation In Liquids For Antimicrobial Applications, Tina Hesabizadeh

Theses and Dissertations

This study aimed to synthesize selenium nanoparticles (Se NPs) by Pulsed Laser Ablation in Liquids (PLAL) and investigate their antibacterial and biological effects, particularly their impact on cell viability and related biological responses. Spherical amorphous Se NPs were produced by irradiating a selenium target using a combination of bottom- and top-ablation protocols. After autoclaving, the amorphous Se NPs were converted into trigonal Se NPs. Se NPs were characterized by using Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and Fourier Transform Infrared Spectroscopy (FTIR). The biological effects of Se NPs were quantitatively assessed through evaluations of cell viability and associated …

Effects Of Mating System And Adaptedness On The Evolution Of Fitness And Mtdna Copy Number In Mitonuclear Mismatched C. Elegans, Zachary P. Dietz, Devshuvam Banerji, Jennifer A. Sullins, Brent W. Bever, Stephen F. Christy, Ulfar Bergthorsson, Vaishali Katju, Suzanne Estes

Biology Faculty Publications and Presentations

Metabolic functioning in nearly all eukaryotes relies on molecular machinery dual-encoded by mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) genomes. The two genomes have sustained an extraordinary degree of cooperation across evolutionary time, preserving the capacity for indispensable processes including oxidative phosphorylation and ATP production, which in turn influence many fitness-related traits. How this cooperation is maintained when one member of the pair is debilitated by deleterious mutation is poorly understood, as is the influence of mutation location (mtDNA or nDNA), mating system, or the potentially compensatory effects of mtDNA copy number changes on the process. We asked whether and …

Immunosuppressive Formulations For Immunological Defense Against Traumatic Brain Injury, Abhirami Thumsi, Abhinav P. Acharya, Jeffrey Capadona, Sanmoy Pathak, Taravat Khodaei, Madan Mohan Chandra Sekhar Jaggarapu, Abhirami P. Suresh

Faculty Scholarship

Traumatic brain injury (TBI) and subsequent neurodegeneration is partially driven by chronic inflammation both locally and systemically. Yet, current clinical intervention strategies do not mitigate inflammation sequelae necessitating the development of innovative approaches to reduce inflammation and minimize deleterious effects of TBI. Herein, a subcutaneous formulation based on polymer of alpha-ketoglutarate (paKG) delivering glycolytic inhibitor PFK15 (PFKFB3 inhibitor, a rate limiting step in glycolysis), alpha-ketoglutarate (to fuel Krebs cycle) and peptide antigen from myelin proteolipid protein (PLP139-151) is utilized as the prophylactic immunosuppressive formulation in a mouse model of TBI. In vitro, the paKG(PFK15+PLP) formulation stimulates proliferation of immunosuppressive regulatory …

Constitutional Futurism As Pedagogy, Jeremiah Chin

Seattle University Law Review

Constitutional Law has transformed from a course on history to a discussion of current events. Cases like Students for Fair Admissions v. Harvard College, Dobbs v. Jackson Women’s Health Organization, and Loper Bright Enterprises v. Raimondo reveal that the study of constitutional law is not a static, or even linear, discussion of constitutional text and history. Law is a shifting, changing enterprise that reflects social constructions of power, authority, and identity. How do we teach, learn, and understand constitutional law that is so laden with history, riddled with theories of consistency and adherence to precedent, but ultimately subject …

The 15-Minute City And Social Behavior Changes In The Tod Area: Blok M-Sisingamangaraja Tod Case Study, Dede Julfikar, Lin Yola

International Review of Humanities Studies

The changing process of the city can be due to economic development that results in urbanization then enlarges the city. This situation affects the growth and evolution of other activities in urban areas such as the emergence of new residential areas, industrial zones, and trade and service (commercial) areas. The government of DKI Jakarta is targetting to develop many public transportation infrastructure due to its target of 2040 70% of Jakarta residents live near by transit points. So that the distance of residential residents to urban facilities can be reached within 15 minutes of walking, cycling or using public transportation. …

Cyber Attacks On Government-Managed Systems: A Social Epistemology Perspective, Aurelia Bunga Anggun Putri Romavella, Fristian Hadinata

International Review of Humanities Studies

This article examines cyberattacks on government-managed systems from the perspective of social epistemology. The development of information technology, particularly the internet, has changed the way governments operate and interact with the public. However, these changes have also created new vulnerabilities to cyberattacks that can disrupt public services, undermine public trust and threaten national security. Social epistemology, with its focus on how knowledge and beliefs are constructed and disseminated in society, provides a useful analytical framework for understanding these cyberattack dynamics. This article examines how cyberattacks affect the production, distribution and validation of knowledge in the context of governance. By analyzing …

Representing Foreign Husbands: A Comparative Study Of Narrative Styles In My Neighbor, Charles, Fadhila Hasby

International Review of Humanities Studies

This study investigates the representation of foreign husbands in South Korean television by analyzing the reality TV show *My Neighbor, Charles*, which features intermarried couples of Korean women and foreign men. It examines the narrative patterns associated with white and non-white foreign husbands. Utilizing the three-act narrative structure theory as an analytical framework, Stuart Hall's concepts of representation and Dyer's work on Whiteness, this research reveals how Korean media, particularly television, reflects unbalanced and racially biased portrayals of foreign husbands. Such unequal representations not only illustrate the practice of racism within the Korean context but also shed light on how …

The Middle Class, The Youth, The Highways: Production Of Space And Urban Memory In Blok M, Jakarta, Bimana Novantara, Yudi Bachrioktora, Lilawati Kurnia

International Review of Humanities Studies

This paper examines the historical and contemporary dynamics of the Blok M area in Jakarta as a public space undergoing a process of spatial, cultural, and symbolic transformation. Using Henri Lefebvre’s theory of the production of space and then relating it to the discourse of urban memory according to Abidin Kusno, this study traces how Blok M developed from the modernist urban planning of Kebayoran Baru after independence to be the epicenter of youth festivity, then declined until it rose again through a place that utilized the memory of this area in the past. This study highlights how the politics …

Advertising Appeals Through Instagram Caption Code Switching, Irma Aulia Irawan, Myrna Laksman-Huntley

International Review of Humanities Studies

The COVID-19 disease required everyone to go into lockdown. All activities and communications were carried out through mobile devices, driving online content consumption to double. The Instagram app, which is part of social media, increased its visits by 43 percent during the lockdown of the COVID-19 pandemic. As users turn to social media, influencers are emerging as figures in shaping online interactions and trends. One of the popular French influencers is Léna Mahfouf (@lenamahfouf). As a global fashion influencer, Mahfouf often uses English transitions in her captions. This qualitative research will identify the types of code-switching found with Poplack's theory …

Factors Influencing Information And Accessibility Of Tuberculosis Prevention Services Among Nomadic Fulani And Host Communities, Nigeria, Abolaji Azeez, Kabiru Salami

Journal of Social, Behavioral, and Health Sciences

Despite efforts to curtail tuberculosis (TB) in Nigeria, the country has not yet attained the global target. This study explored the dynamics of access to information about TB control and prevention among nomadic Fulani and their host communities. We used a mixed-methods approach and multistage sampling technique to recruit 812 respondents for the survey, and we conducted 18 in-depth interviews across six local government areas. The results indicated generally low access to TB information and services, with only 2% of nomadic Fulani engaging in TB prevention activities compared to 6.7% of host community members. Yoruba respondents had significantly higher odds …

Engineered Bifidobacterium Strains Colonization At Tumor Sites: A Novel Approach To The Delivery Of Cancer Treatments, Rhea Amonkar, Ashley Ann Uy, Pablo Ramirez, Harina Patel, Jae Jin Jeong, Nicole Oyinade Shoyele, Vidhi Vaghela, Ashakumary Lakshmikuttyamma

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Bacteria-mediated cancer therapy represents a novel and promising strategy for targeted drug delivery to solid tumors. Multiple studies have demonstrated that various Bifidobacterium species can selectively colonize the hypoxic microenvironments characteristic of solid tumors. Leveraging this property, Bifidobacterium has been explored as a delivery vector for a range of anti-cancer approaches such as immunotherapy, nanoformulated chemotherapeutics, and gene therapy. Notably, anti-angiogenic genes such as endostatin and tumstatin have been successfully delivered to colorectal tumors using Bifidobacterium infantis and Bifidobacterium longum, respectively. Additionally, Bifidobacterium bifidum has been employed to transport doxorubicin and paclitaxel nanoparticles to breast and lung tumor sites. …

Engineered Bifidobacterium Strains Colonization At Tumor Sites: A Novel Approach To The Delivery Of Cancer Treatments, Rhea Amonkar, Ashley Ann Uy, Pablo Ramirez, Harina Patel, Jae Jin Jeong, Nicole Oyinade Shoyele, Vidhi Vaghela, Ashakumary Lakshmikuttyamma

College of Pharmacy Faculty Papers

Bacteria-mediated cancer therapy represents a novel and promising strategy for targeted drug delivery to solid tumors. Multiple studies have demonstrated that various Bifidobacterium species can selectively colonize the hypoxic microenvironments characteristic of solid tumors. Leveraging this property, Bifidobacterium has been explored as a delivery vector for a range of anti-cancer approaches such as immunotherapy, nanoformulated chemothera- peutics, and gene therapy. Notably, anti-angiogenic genes such as endostatin and tumstatin have been successfully delivered to colorectal tumors using Bifidobacterium infantis and Bifidobacterium longum, respectively. Additionally, Bifidobacterium bifidum has been employed to transport doxorubicin and paclitaxel nanoparticles to breast and lung tumor …

Bold New Bioweapons: Part 2 — Bold Bolstering Of Deterrence And Defense, James Giordano

Strategic Insights

This commentary, Pt. 2 of the Bold New Bioweapons series, argues that modern biological threats demand a proactive transformation of deterrence and defense strategies. Building on earlier analysis of detection and attribution challenges, Dr. Giordano asserts that emerging life sciences and related technologies, such as synthetic biology, gene editing, and AI-driven bioengineering blur distinctions between legitimate research and weaponizable capabilities. This undermines traditional deterrence frameworks. To address these complexities, the article proposes adaptive, interoperable, and ethical approaches that integrate advanced biosurveillance, precision bioinformatics, AI-enabled threat modeling, and global collaborative governance. It emphasizes the need for robust international norms and resilient …

Secure Frameworks For User Motion Data In Virtual Reality, Jayasri Sai Nikitha Guthula

Theses and Dissertations

Virtual Reality is an innovative technology transforming industries such as gaming, healthcare, and remote collaboration. The increasing deployment of these systems results in the continuous collection of telemetry data, including motion patterns, hand gestures, and spatial interactions. This data is valuable for enhancing user experiences and optimizing system performance. However, it also introduces significant privacy risks. Unlike traditional digital footprints, motion data captures fine-grained physical behaviors that can be linked to individual users, making anonymization ineffective in preventing re-identification.This research introduces secure frameworks for user motion data in virtual reality, each proposed framework addressing privacy preservation from a different angle. …

Magnetic Macro Pendulum Design And Real-Time Control Application: Simulation And Experiment, Hüseyi̇n Yildiz, Serdar Yilmaz, Yasemi̇n Poyraz Koçak, Erol Uzal

Turkish Journal of Electrical Engineering and Computer Sciences

Over the last decade, the number of studies in the field of magnetic micro robots has significantly increased due to expectations of performing microsurgery, drug delivery, and similar medical procedures. Magnetic micro robots have advantages over other types of micro robots in terms of having independent designs for rotor and stator structures. Magnetic micro robots can be controlled by magnetic fields and can be programmed to move in certain directions and to perform various functions. This paper implements the computer-aided real-time control of a single-arm micro-pendulum structure to (eventually) perform cell manipulation tasks. The mechanical structure, mathematical model, control circuit …

Perceived Impact Of Participating As A Former Immigrant High School Athlete In A Program That Prioritized Social-Emotional Needs And Self-Determination Of Young Adult Males, Filip Cejovic

Walden Dissertations and Doctoral Studies

Many studies have confirmed the positive impacts of extracurricular activities on students' academic achievement and social success, but also revealed that few educational policies go beyond addressing the most basic needs of language and lunch for immigrant students. As the process of assimilation can impact numerous factors and long-term outcomes for these students, this study explored extracurricular program structures that prioritize participants’ psychological needs and whether these structures have a positive impact on immigrant students’ self-determination, intrinsic motivation, and future success. This qualitative, practice-focused case study examined a purposeful sample of one boys’ high school soccer program at a public …

Effective Strategies For Deterring Unethical Behavior In U.S. Financial Institutions, Samuel Akinlade Sanni

Walden Dissertations and Doctoral Studies

Unethical employee behavior in U.S. financial institutions continues to erode organizational trust and firms’ brand reputation. Leaders of financial institutions are concerned that unethical employee behavior can negatively impact firms’ profitability, competitiveness, and sustainability. Grounded in Kaptein’s corporate ethics virtue (CEV) model, the purpose of this qualitative pragmatic inquiry study was to explore how organizational ethical cultures influence employees’ behaviors. Data were collected through semistructured interviews with a sample of eight leaders in New York financial institutions, with a minimum of 5 years of successful experience in building a positive ethical environment, and by analyzing publicly available documents to support …

Table Of Contents

Seattle University Law Review

Table of Contents

Can The Law Protect My Craft? How Gaps In Copyright Of Knitting Patterns Symbolize A Greater Struggle For Protecting Traditionally Feminine Forms Of Intellectual Property, Kysa Walzer

Seattle University Law Review

The purpose of this article is to demonstrate the application of intel-lectual property rights within the context of copyright protection of knit-ting patterns. The article will discuss the underutilization of copyright pro-tection for knitters and crafters and its larger impact upon craft and indus-try traditionally comprised of women. Part I introduces knitting patterns and a short history of copyright protections. Part II discusses the specific areas within knitting patterns and the knitting community which give rise to legal grey areas for copyright protection. Part III discusses the larger implications of copyright and intellectual property in spaces where women traditionally make …

A Novel Microdosimetry-Based Formalism For Cell Survival Modelling Applicable To Hypofractionated Radiotherapy, Oleg N Vassiliev, Radhe Mohan

Faculty, Staff and Student Publications

Objectives

Hypofractionated radiotherapy requires reliable cell survival models for doses much higher than the standard 2 Gy, for which the linear-quadratic (LQ) model is not applicable. We developed an alternative approach applicable to both low doses and high doses used in hypofractionated treatments and radiobiological experiments.

Approach.

We combined a standard microdosimetric technique with a recently introduced non-LQ cell survival model. Our formulation accounts for cell damage by multi-track events involving any number of particles. This is necessary for modelling cell survival at therapeutic doses. We characterise each cell type by the size �� of the sensitive volume (SV) and …

Use Of Cholic Acid In Smith-Lemli-Opitz Syndrome (Slos): Real-World Patient Outcomes, Edwin Ferren, Paul R Hillman, Amy Kritzer, Joseph Ray, Alvaro Serrano, Hope Northrup, Paige Roberts, Rana Dutta, Tiziano Pramparo, Pamela Vig, Robert D Steiner

Faculty, Staff and Student Publications

Background: Smith-Lemli-Opitz Syndrome (SLOS) is an autosomal recessive disorder of cholesterol biosynthesis caused by biallelic pathogenic variants in DHCR7, which encodes the enzyme 7-dehydrocholesterol reductase (DHCR7). SLOS is a multisystemic disorder affecting various aspects of health, including growth, development, behavior, and quality of life, underscoring the need for safe, efficacious interventions that limit disease burden. DHCR7 enzyme deficiency leads to a "metabolic block" resulting in decreased cholesterol production and accumulation of its precursor 7-dehydrocholesterol and the secondary isomer 8-dehydrocholesterol. Reduced cholesterol synthesis, in turn, leads to decreased levels of cholic acid (CA), an endogenous bile acid synthesized from cholesterol and …

Melanoma Antigens In Pediatric Medulloblastoma Contribute To Tumor Heterogeneity And Species-Specificity Of Group 3 Tumors, Rebecca R J Collins, Rebecca R Florke Gee, Sima Tozandehjani, Tara Bayat, Maria Camila Hoyos Sanchez, Juan Sebastian Solano Gutierrez, Barbara Breznik, Anna K Lee, Samuel T Peters, Jon P Connelly, Shondra M Pruett-Miller, Martine F Roussel, Dinesh Rakheja, Heather S Tillman, Patrick Ryan Potts, Klementina Fon Tacer

Faculty, Staff and Student Publications

Medulloblastoma (MB) is the most malignant childhood brain cancer. Group 3 MB (G3 MB) subtype accounts for about 25% of MB and is associated with the worst outcomes. Herein, we report that more than half of G3 MB tumors express melanoma antigens (MAGEs), which are potential prognostic and therapeutic markers. MAGEs are cancer-testis antigens, aberrantly expressed in several adult cancers, and associated with poorer prognosis and therapy resistance; however, their role in pediatric cancers is mostly unknown. This study aimed to determine whether MAGEs are activated and important in pediatric MB. We obtained formalin-fixed paraffin-embedded tumor samples of 34 patients, …

Analysis Of A Saline Dust Storm From The Aralkum Desert – Part 2: Atmospheric Flow Precursors In The Euro-Atlantic Region, Xin Xi

Michigan Tech Publications

Wind-blown dust emissions from the man-made Aralkum Desert pose significant environment and human health risks across Central Asia. Yet, little is known about the atmospheric circulation patterns favoring dust outbreaks from the region. This study examines the role of upstream atmospheric blocking and recurrent transient Rossby wave packets (RWPs) in initiating a severe dust storm from the Aralkum Desert in May 2018. Results show that the dust event was triggered by an unusual early-summer cold air outbreak and attendant postfrontal northerly winds reaching 24–31 m/s. The compound cold air and dust outbreaks were preceded by repeated meridional flow amplification linked …

Effectiveness Of Vaginal Magnesium Sulfate On Pain And Labor Duration: A Systematic Review And Meta-Analysis, Somayeh Makvandi, Elham Manouchehri, Mahdieh Razi, Samaneh Alinejad Mofrad, Mona Larki

Sultan Qaboos University Medical Journal

This systematic review and meta-analysis aimed to evaluate the effectiveness of vaginal magnesium sulfate (MgSO4) administration during labour. A comprehensive search was conducted across six databases up to 30 July 2024, and updated on 13 January 2025, with no restrictions on time, language, or geographical region. The risk of bias was assessed using the RoB 2 tool, and the certainty of evidence was evaluated using GRADEpro. A total of seven randomised controlled trials were included. The meta-analysis demonstrated that topical magnesium sulfate significantly increased cervical dilatation by 2.27 cm (95% confidence interval [CI]: 1.98 to 2.56; PPP

Creating Sustainable School And Home Gardens: Companion Planting, Ruby Mohr, Kathy Cabe Trundle, Rita Hagevik

All Current Publications

Companion planting is an agricultural practice in which two or more plants are intentionally grown together to enhance mutual productivity. The special relationships that plants have with other organisms help create balanced ecosystems. Companion planting can be used to reduce the need for chemical fertilizers and pesticides, increase yields, and attract beneficial insects such as pollinators.

Urban Landscape Recovery And Lulc Analysis: A Deep Learning Approach To Post-Extreme Rainfall Impacts In Dubai, Xin Hong

All Works

From April 14 to 18, 2024, the United Arab Emirates (UAE) experienced its heaviest rainfall in 75 years, resulting in widespread flooding across multiple emirates, including Dubai. This study utilizes high-resolution PlanetScope imagery and a U-Net deep learning model to assess the flood impact and analyze post-rainfall recovery patterns in Dubai’s urban landscape. By integrating Sentinel-2derived land use and land cover (LULC) data to refine the training dataset, a high-accuracy U-Net model was developed through transfer learning that effectively classified pre- and post-rainfall LULC. Post-rainfall LULC change detections indicate that 23.8 km² of land was flooded, which is equivalent …

2025 Deerfield Fair 4-H Building Project Premium Book, Extension

UNH Cooperative Extension

No abstract provided.

Cultural Worldview And Rural Consumer Preferences For Genetically Modified Foods, Nathan P. Kemper

Agricultural Economics and Agribusiness Faculty Publications and Presentations

The consumer acceptance of genetically modified (GM) foods varies widely based on personal values and social context. This study investigates how cultural worldviews—measured through the Individualism–Communitarianism and Hierarchical–Egalitarianism dimensions—affect willingness to pay (WTP) for food labeling attributes related to GM content. We surveyed 932 U.S. primary grocery shoppers and conducted a discrete choice experiment (DCE) with poultry product options. Using a Mixed Logit model and supplemental cognitive data from Query Theory, we find that rural individualists are more accepting of GM-labeled products. At the same time, urban communitarians show a stronger preference for non-GM labels. These results offer insight into …