Digital Commons Network^™

Can We All Get Along? Assessing Interdisciplinary Collaborations At A School Of Health Sciences, Merly Thomas

Dissertations

This study explores the process, conceptualization, and understanding interdisciplinary collaborations through a lens of organizational learning. More specifically, this research focuses on the barriers, challenges, definitions, and self-constructed metrics with a health sciences campus, situated in a religious institution in the Midwest. Through a single institution qualitative case study, this research interviews 16 participants, spanning across program coordinators, directors, and individuals in both operations and administration, to examine how a school of health sciences housed at an academic medical campus, operates across disciplines and departments, to advance interdisciplinary collaborations that foster a more productive and engaged workforce. Findings illuminate the …

Comprehending Students' Experiences With A Language Learning Resource Center: A Descriptive Phenomenological Study Of College Life And Belonging, Paulina Dzieza

Dissertations

This study explores the impact of Language Learning Resource Center (LLRC) services on college students' overall college experience and their sense of belonging on campus. In the constantly evolving world of higher education, higher education institutions work to provide welcoming spaces where students can flourish academically and socially. In higher education, where there is a growing focus on student support services, the LLRC is essential for promoting academic achievement, cross-cultural interaction, and social integration for foreign language learners. This qualitative study, guided by a combined theoretical framework of Community of Practice and Ethics of Care, aims to advance knowledge of …

Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina

Jurnal Kajian Bimbingan dan Konseling

The rate at which Nigerian youths take up arms to perpetuate anti-social acts has become a major concern to the populace. This study investigated the influence of child abuse on youth restiveness as perceived by security personnel in Ilorin metropolis, Kwara State. The study was a survey research. The population of this study comprised all security personnel in Ilorin metropolis and 200 respondents were randomly selected for the study. A questionnaire entitled “Influence of Child Abuse on Youths Restiveness Questionnaire” (ICAYRQ) was used to collect data for the study. Percentage was used to analyse the demographic data. Mean and rank …

Contradictory Role Of Forgiveness Against Undergraduate Students’ Online Game Addiction Tendency: Two Preliminary Studies Before And During The Covid-19 Pandemic, Amalia Rahmandani

Jurnal Kajian Bimbingan dan Konseling

Two quantitative and cross-sectional preliminary studies were conducted to address the issues of forgiveness in the context of the tendency to online game addiction among university students in Semarang, Indonesia. A forgiveness scale comprising three dimensions of forgiveness, including forgiveness of self, others, and situations, as well as two separate scales of the tendency to online game addiction, was used. Samples consisting of two groups of online gamers were obtained using a convenience sampling technique. The sample size of Study 1, conducted prior to the onset of the COVID-19 pandemic, was 114 participants (Male = 98.25%) from four game centers. …

The Mediating Role Of Smartphone Usage In The Relationship Between Working Mothers And Children’S Social Interaction, Wulan Patria Saroinsong, Mochamad Nursalim, Azmawaty Binti Mohamad Nor

Jurnal Kajian Bimbingan dan Konseling

This study explores how smartphone usage acts as a mediator in the connection between working mothers and social interaction among children aged 3–6 years in East Java, Indonesia. Due to the insufficient reading and writing skills of children in this age range to complete questionnaires for the children’s interaction variable, data were gathered from their parents’ perspective, notably working mothers, who offered insights into their parenting behaviors and their children’s interaction patterns when using the smartphone. The research utilized a mediation analysis design to examine the relationships among the variables. A structured questionnaire was distributed to a sample of 400 …

Spartan Daily, August 28, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 4

The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery

Faculty, Staff and Student Publications

Not available.

Adams Contribute To Triple Negative Breast Cancer Via Mtorc1 Pathway: Targeting Adam-Mtor Axis Improves Efficacy, Shuying Liu, Huiqin Chen, Mihai Gagea, Lorenzo Federico, Fan Zhang, Javier Gomez, Kim-Anh Do, William F Symmans, Gabriel N Hortobagyi, Gordon B Mills, Ana M Gonzalez-Angulo, Debasish Tripathy

Faculty, Staff and Student Publications

Breast cancer is the most frequently diagnosed cancer globally and the second leading cause of cancer-related deaths in American women. Triple-negative breast cancer (TNBC) lacks estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Thus, fewer targeting therapies are available for this most aggressive subtype. The A Disintegrin and Metalloproteinase (ADAM) family plays a vital role in cancer pathophysiology. Previous studies focused on single ADAM members. However, none of these have entered into the clinical arena as diagnostics or therapeutics for breast cancer. In this study, we demonstrate the upregulation of a panel of ADAM members in TNBC, …

Safe Nurse Staffing For Scotland: A Cross-Sectional Observational Study, Eileen T. Lake

Sigma Foundation for Nursing Research Grant Reports

Amid a global nurse staffing crisis, the project is designed to describe the baseline nursing standards adherence, nurse staffing, and work environments in hospitals before the April 2024 implementation of Scotland’s Safe Staffing Act 2019. Quantifying the variation is important to evaluate the Law’s subsequent implementation (whether hospitals meet standards) and impact (whether standards improve quality and safety). The results will aid policymakers by providing baseline data from Scotland before the Law is implemented and an informative exemplar for states and countries globally as many government authorities consider nurse staffing legislation.

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Faculty Senate Agenda, Georgia Southern University, Faculty Senate

Faculty Senate Agendas

No abstract provided.

Electricity And The Environment, Praveen Kumar

Doctoral Theses

This thesis explores the intersection of electricity and the environment across three studies. The first study examines the 2018 policy in Telangana that removed agricultural electricity rationing, providing farmers with 24-hour power. Using detailed panel data and a difference-in-differences approach, the study finds a 53% rise in agricultural electricity consumption and an expansion of water-intensive rice cultivation relative to boundary districts in neighboring states. However, no statistically significant change is detected in groundwater depth measured by government monitoring wells, suggesting that current monitoring systems may not adequately capture water availability in fragmented hard-rock aquifers. The second study evaluates a subsidized …

Feasibility Evaluation Of Secure Offline Large Language Models With Retrieval-Augmented Generation For Cpu-Only Inference, Erick Tyndall, Torrey J. Wagner, Colleen Gayheart, Alexandre Some, Brent T. Langhals

Faculty Publications

Recent advances in large language models and retrieval-augmented generation, a method that enhances language models by integrating retrieved external documents, have created opportunities to deploy AI in secure, offline environments. This study explores the feasibility of using locally hosted, open-weight large language models with integrated retrieval-augmented generation capabilities on CPU-only hardware for tasks such as question answering and summarization. The evaluation reflects typical constraints in environments like government offices, where internet access and GPU acceleration may be restricted. Four models were tested using LocalGPT, a privacy-focused retrieval-augmented generation framework, on two consumer-grade systems: a laptop and a workstation. A technical …

Alterations In Ether Lipid Metabolism In Obesity Revealed By Systems Genomics Of Multi-Omics Datasets, Yvette Schooneveldt, Sudip Paul, Kevin Huynh, Habtamu B. Beyene, Natalie A. Mellett, Gerald F. Watts, Joseph Hung, Jennie Hui, John Beilby, John Blangero

Human Genetics Publications

Ratios between two metabolites are sensitive indicators of metabolic changes. Lipidomic profiling studies have revealed that plasma ether lipids, a class of glycero- and glycerophospho-lipids with reported health benefits, are negatively associated with obesity. Here, we utilized lipid ratios as surrogate markers of lipid metabolism to explore the processes underlying the inverse relationship between ether lipid metabolism and obesity. Plasma lipidomics data from two independent human cohorts (n = 10,339 and n = 4,492) were integrated to assess the associations between 82 lipid ratios and obesity-related markers in males and females. Results were externally validated using mouse transcriptomics data …

Evolving Paradigms In Acute Myeloid Leukemia: Personalized Approaches To Therapy Across Age And Risk Groups, Sumeet Yadav, Utsav Joshi, Guleid Hussein, Mohamed Warsame, Bolun Liu, Abhash Shrestha, Peter Krastev, Hariprasad Reddy Korsapati, Amrit Singh

Student Publications

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by the clonal proliferation of myeloid precursors and rapid progression. Historically consisting of intensive chemotherapy, AML management has evolved significantly due to advances in molecular diagnostics and risk stratification. This review discusses current therapeutic paradigms in AML, emphasizing the growing role of personalized medicine across age and risk groups. For younger, fit patients, intensive regimens such as the "7 + 3" protocol remain the standard, often enhanced by targeted agents like FMS-like tyrosine kinase 3 (FLT3) and IDH inhibitors. Older or unfit individuals benefit from low-intensity treatments such as hypomethylating …

Pressure And Force Dynamics In Artificial Muscle Actuators: A State-Space And Optimization-Based Approach, Mohammad Elzein

Dissertations and Theses

This two-part investigation explores the dynamic behavior of braided pneumatic actuators (BPAs) under bio-inspired pulse modulation, with the aim of improving their biomimetic force output and control. The first study examines the effect of pulse length and inter-pulse timing on BPA performance, revealing that force output is highly sensitive to the temporal structure of input pulses mirroring biological muscle behavior. Using dual-pulse actuation schemes, the results demonstrate that force responses exceed the additive contributions of individual pulses, with peak amplification occurring consistently at a 27 ms inter-pulse gap. Shorter pulse lengths (10–20 ms) yielded the highest normalized force increases, up …

C-C Motif Chemokine Receptor-Like 2 Promotes The Interferon-Γ Signaling Response In Myeloid Neoplasms With Erythroid Differentiation And Mutated Tp53, Nour Sabiha Naji, Sergiu Pasca, Theodora Chatzilygeroudi, Pablo Toledano-Sanz, Joseph Rimando, Yuju An, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun, Abdulmuez Abdulmalik, Chen Lossos, Tatianna R Boronina, Ilias Sinanidis, Panagiotis Tsakiroglou, Priyanka Fernandes, Christopher Esteb, Alexander J Ambinder, Robert N Cole, Rena Xian, Ivana Gojo, Suman Paul, Mark J Levis, Amy E Dezern, Leo Luznik, Styliani Karanika, Linda S Resar, Richard J Jones, Frederick Bunz, Lukasz Gondek, Marios Arvanitis, Theodoros Karantanos

Faculty, Staff and Students Publications

Patients with myeloid neoplasms with loss-of-function TP53 mutations and erythroid differentiation have poor outcomes, and a better understanding of disease biology is required. Upregulation of interferon-γ (IFN-γ) signaling has been associated with acute myeloid leukemia (AML) progression, selection of TP53 mutated clones and chemotherapy resistance, but its drivers remain unclear. In this study, we found that the surface receptor C-C motif chemokine receptor-like 2 (CCRL2) is overexpressed in AML with erythroid differentiation and TP53 mutations compared to other AML subtypes and healthy hematopoietic cells. CCRL2 knockout (KO) suppressed erythroleukemia growth in vitro and in vivo. Further proteomics and transcriptomics analysis …

Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Erin Batchelor, Rachel A Kentor, Calliope Reeves, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye

Faculty, Staff and Students Publications

Background/objectives: High-quality prognostic communication in pediatric oncology is essential to support informed decision making, foster trust, and honor goals of care. While families differ in their preferences for how prognosis is discussed, clinicians often rely on assumptions rather than directly eliciting these preferences, risking misalignment and distress. To address this gap, we aimed to characterize patient, parent, and oncologist perspectives on key variables, experiences, and circumstances that influence their preferences for prognostic communication.

Methods: Semi-structured interviews were conducted with 85 participants (25 patients aged 12-25, 40 parents, and 20 oncologists) to elicit their preferences for prognostic communication and the reasons …

Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes, Huanwen Chen, Marco Colasurdo, Hidetoshi Matsukawa, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Jonathan A Grossberg, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Ergun Daglioglu, Richard Williamson, Pedro Navia, Reade De Leacy, Shakeel Chowdhry, David J Altschul, Alejandro M Spiotta, Peter Kan

Faculty, Staff and Students Publications

Introduction: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.

Patients and methods: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …

Time Ticks Slowly For Kidney Transplant Reform: Eskd Patient Challenges And Opportunities, Gregory P. Hess

College of Population Health Faculty Papers

No abstract provided.

Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi

2020-Current year OA Pubs

Cannabinoid receptor 1 (CB1) has been implicated in multiple inflammatory diseases by regulating pro-inflammatory mediators or altering immune cell polarization. However, the expression and direct functional role of CB1 in T cells remain largely unexplored. Here, we demonstrate that primary murine T cells express CB1 and that its novel agonist, BI-5756, directly increases the frequencies of regulatory T cells (Tregs) in primary murine pan T cells after activation. In addition, BI-5756 exhibits an in vivo protective effect against graft-versus-host disease (GvHD), an allogeneic T cell-mediated inflammatory complication after allogeneic hematopoietic cell transplantation (allo-HCT), resulting in an improved overall survival with …

Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes, Huanwen Chen, Joshua Osbun, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.

PATIENTS AND METHODS: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …

Thriving Through Transition: Innovative Resilience Training For New Nurses, Christene Annette Taylor

Creating Healthy Work Environments (CHWE)

The transition from academic settings to professional nursing practice is a critical period marked by high stress and a heightened risk of burnout for newly licensed nurses. This study introduces an innovative Resilience Training Program designed to address these challenges and foster a healthier work environment. Uniquely grounded in Transition Shock Theory, the program focuses on building psychological resilience, providing newly licensed nurses with the skills necessary to navigate and thrive in high-pressure settings.

Employing a quantitative quasi-experimental one-group pre-and-post design, the study assessed resilience using the CD-RISC 10 scale. The results demonstrated a significant improvement in resilience scores post-intervention, …

Supply Waste Reduction Workgroup: A Go Green Initiative, Aswathy Nair, Givenchy Victorio, Durga Basnet, Shani Pinky

Creating Healthy Work Environments (CHWE)

Background: Previous studies report that the healthcare industry significantly contributes to environmental degradation and intensive care units (ICUs) are a major generator of waste (Barbariol, 2023). Many ICU staff and support staff personnels have expressed frustration over extra supplies being brought into the room and later discarded. The “GreenICU” aims to reduce the million-pound contribution of medical waste to our landfills.

Method: "GreenICU” focused on four key areas. First, an ICU green team was formed, consisting of PCAs and nurses from day and night shifts. Forming a team is crucial for gathering input, making recommendations, and ensuring the sustainability of …

Calm The Bone! Transforming Orthopedic Clinics Into Thriving Work Environments With Code Lavender, Tania Mae Golo-Atkin, Jodie Mae Bernardino Shiba, Daniel A. Colllins, Danica Jane Austero Calayag

Creating Healthy Work Environments (CHWE)

BACKGROUND: Gibson et al. 1 first used “Code lavender” to describe part of a bereavement program for NICUs. Since then, code lavender evolved initially to caregiver and health care provider support to now mental health well-being for nurses as part of efforts to decrease nursing burn out. 2 Several hospitals have trialed or implemented a variation of a code lavender program; however, the majority of these focus on inpatient staff and the emergency department. 3–5 There is a dearth of literature about using code lavender in outpatient or ambulatory care settings in general. The purpose of this presentation is to …

Addressing Job Satisfaction In Emergency Services: An Exploratory Study, Jacqueline Christianson, Tiffany Warthon, Tala Fuad Abuzahra

Creating Healthy Work Environments (CHWE)

Purpose: Emergency services professionals (ESPs), like emergency medical technicians, paramedics, and registered nurses, work in stressful, low-resource environments and are vulnerable to work-related burnout (Crowe et al., 2020; Hinderer et al., 2014). While many ESPs are motivated by compassion for others, most ESPs never learn what happened to the patients they cared for (Ntatamala & Adams, 2022; Patterson et al., 2005). Disconnection from patient outcomes may limit compassion satisfaction among ESPs and make it more difficult to actualize their role in patient care and contribute to burnout, which negatively affects patient care (Georgakakos et al., 2022). The purpose of this …

Addressing Health And Healing In The Work Environment Through A Wellness Yoga Class, Norah M.M. Airth-Kindree, Der-Fa Lu

Creating Healthy Work Environments (CHWE)

With escalating nursing faculty shortages, faculty retention is important. Developing an infrastructure to support work-life balance and create programs that address wellness is needed to enhance nursing faculty satisfaction by improving well-being and career satisfaction. Following the Healthy Nurse Healthy Nation initiative launched in 2017 to improve the health of nurses within the United States, educational settings must promote and maintain healthy work environments on a more personal level. Within a midwestern College of Nursing, faculty and instructional academic staff satisfaction surveys are deployed every three years. Overall job satisfaction has plummeted from 90% satisfaction in 2016 to 28% satisfaction …

Examining The Relationship Between Moral Distress And Grit Among Transplant Professionals, Preston H. Miller, Haley Hoy, Shikha Modi, Antonia Primus

Creating Healthy Work Environments (CHWE)

‘Moral distress’ was originally conceptualized among nurses in 1984 by Professor Andrew Jameton as occurring when a nurse “knows the right thing to do, but institutional constraints make it nearly impossible to pursue the right course of action.” Moral distress has since been studied among a variety of healthcare professionals and can further be characterized as occurring when clinicians are constrained from taking what they believe to be ethically appropriate actions or are forced to take actions that are ethically inappropriate based on their professional obligations, resulting in a sense of complicity and wrongdoing. Conversely, the concept of grit has …

Nurses’ Perspectives Of Their Workplace Well-Being At A Tertiary Hospital In Saudi Arabia, Vimela Moodley, Diane Ross, Maab Basha, Asmaa Khan, Naomi Tuifao, Jennifer De Beer, Jamila Alsharani, Abeer Aljoudy

Creating Healthy Work Environments (CHWE)

Nursing is a demanding profession that requires substantial physical and emotional resilience, making nurses vulnerable to burnout and stress due to high job expectations and challenging work environments. In this context, many nurses are reluctant to seek help or divulge personal stressors, which can adversely affect their performance and coping skills. As a Magnet-recognized healthcare facility, the organization prioritizes outstanding patient outcomes and strives to enhance workplace conditions for nurses. A collaboration between the Magnet department and the Nurse Retention Office aims to understand the influence of the work environment on nursing wellbeing, with a focus on uncovering hidden psychological …

Night To Light Revive Before You Drive, Imelda S. Oca, Armie Poralan, Grace Marie Delgado, Mary Ann Sison, Khadijatu A. Bah

Creating Healthy Work Environments (CHWE)

Background: Drowsy driving and commuting accidents following a night shift are common among healthcare workers including registered nurses (RNs)⁸. Mounting evidence suggests that there is a significantly higher adverse driving event following a night shift^3,4,5,6. The Night to Light Revive Before You Drive is a project of the Night Shift Shared Governance Council which supports the recommendations for health equity in the Future of Nursing 2020-2030 report by the National Academy of Medicine⁹. Through interventions specific to the challenges faced by night shift RNs, the project aims to increase safety awareness to combat drowsy …