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Childhood Loneliness And Cognitive Decline And Dementia Risk In Middle-Aged And Older Adults, Jinqi Wang, Danyang Jiao, Xiaoyu Zhao, Yixing Tian, Haibin Li, Xia Li, Chen Sheng, Lixin Tao, Hui Chen, Zhiyuan Wu, Xiuhua Guo Sep 2025

Childhood Loneliness And Cognitive Decline And Dementia Risk In Middle-Aged And Older Adults, Jinqi Wang, Danyang Jiao, Xiaoyu Zhao, Yixing Tian, Haibin Li, Xia Li, Chen Sheng, Lixin Tao, Hui Chen, Zhiyuan Wu, Xiuhua Guo

Research outputs 2022 to 2026

Importance: Adult loneliness has been linked to cognitive decline and dementia risk, but the long-term implications of childhood loneliness remain underexplored. Objectives: To investigate whether childhood loneliness is associated with cognitive decline and dementia risk and whether adult loneliness mediates or modifies these associations. Design, Setting, and Participants: This cohort study used data from the China Health and Retirement Longitudinal Study, a nationally representative cohort study conducted between June 1, 2011, and December 31, 2018, with a maximum follow-up of 7 years. Data analyses were performed from October 1, 2024, to January 15, 2025. Exposure: Childhood loneliness was defined as …


Mepolizumab Alters Gene Regulatory Networks Of Nasal Airway Type-2 And Epithelial Inflammation In Urban Children With Asthma, Courtney L Gaberino, Michelle A Gill, Jeffrey Stokes, Et Al. Sep 2025

Mepolizumab Alters Gene Regulatory Networks Of Nasal Airway Type-2 And Epithelial Inflammation In Urban Children With Asthma, Courtney L Gaberino, Michelle A Gill, Jeffrey Stokes, Et Al.

2020-Current year OA Pubs

Mepolizumab (anti-IL5 therapy) reduces asthma exacerbations in urban children with exacerbation-prone eosinophilic asthma. We previously utilized nasal transcriptomics to identify inflammatory pathways (gene co-expression modules) associated with asthma exacerbations despite this therapy. In this study, we applied differential gene correlation analysis on these targeted gene co-expression modules to gain better insight into the treatment effects on correlation structure within gene networks. Mepolizumab treatment resulted in loss of correlation amongst eosinophil-specific genes but conservation and even strengthening of correlation amongst mast cell-specific genes, T2 cytokines, and airway epithelial inflammatory genes. Notably, mepolizumab induced significant gain in correlation of genes associated with …


Healing The Sacred: The Fight To Restore Onondaga Lake And Honor Indigenous Land, Adam Dj Brett, Betty Lyons Hill Sep 2025

Healing The Sacred: The Fight To Restore Onondaga Lake And Honor Indigenous Land, Adam Dj Brett, Betty Lyons Hill

International Journal on Responsibility

The Onondaga Nation is petitioning the Organization of American States (OAS) for land rights to Onondaga Lake, a notoriously polluted body of water in Central New York State. The Onondaga Nation is one of six nations of the Haudenosaunee Confederacy (Iroquois), and Onondaga Lake is the sacred site where Gayanashagowa, the Great Law of Peace, was established. As Keepers of the Central Fire, the Onondaga Nation bears the responsibility of maintaining unity and peace within the Haudenosaunee Confederacy. This article examines the history of the lake, its significance to the Haudenosaunee Confederacy, and the consequences of its desecration through …


Fun! Friends! Famous People! Why Fans Attend Anime Conventions, Billy Tringali, Maria Alberto, Jeremiah Martinez Sep 2025

Fun! Friends! Famous People! Why Fans Attend Anime Conventions, Billy Tringali, Maria Alberto, Jeremiah Martinez

Proceedings from the Document Academy

In 2021 during the global Covid-19 lockdowns, Billy and Maria ran an IRB-exempted online survey, looking to hear from fans who attend anime conventions. Conventions had been shut down as non-essential services that drew large crowds, and we hoped to capture a screenshot of this moment, to better learn from it in the future. And the resulting data collection went quite well – we were able to partner with a major anime organization to share the survey, and our 1000+ respondents had a lot to say about the conventions they were missing during lockdowns.

Ultimately, we found a significant emphasis …


How Subversive Is Shipping Really? An Analysis Of Heteronormative Elements In Same-Sex Relationships Focused On German-Language Anime And Manga Fan Fiction, Saskia Dreßler Sep 2025

How Subversive Is Shipping Really? An Analysis Of Heteronormative Elements In Same-Sex Relationships Focused On German-Language Anime And Manga Fan Fiction, Saskia Dreßler

Proceedings from the Document Academy

This study investigates whether German-language fan fictions featuring lesbian and gay characters within the anime and manga domain can be regarded as genuinely queer. It situates these fan works within the specific traditions and practices of German fandom. Employing qualitative content analysis, the research examines two prominent fandoms, Naruto and Sailor Moon, focusing on the presence of heteronormative narrative patterns in fan fiction with queer protagonists. The study analyzes which aspects of the original media are adapted and how these adaptations shape the portrayal of queer identities. Furthermore, fan comments are examined to assess the extent to which readers …


Homeschooling: An Alternative Learning Modality For K-12 Students In The Post-Pandemic Era, Alyza Eve N. Bayudan, Maia Katerina C. Bautista, Sapi Kabbigat Yawi B. Bimuyag, Enrico Angelo Noel R. Delenela, Charles Josef L. Kumalao, Jonathan O. Langaoan, Alfonso B. Astudillo Iii Sep 2025

Homeschooling: An Alternative Learning Modality For K-12 Students In The Post-Pandemic Era, Alyza Eve N. Bayudan, Maia Katerina C. Bautista, Sapi Kabbigat Yawi B. Bimuyag, Enrico Angelo Noel R. Delenela, Charles Josef L. Kumalao, Jonathan O. Langaoan, Alfonso B. Astudillo Iii

DLSU Senior High School Research Congress

The rise of homeschooling amidst the COVID-19 pandemic, particularly in the Philippines, prompted this study to explore its viability as an alternative to traditional schooling. Concerns over health and dissatisfaction with existing educational systems drove parents to opt for homeschooling despite challenges such as limited resources and socialization opportunities. Utilizing interviews, online surveys, and onsite observations, this research aimed to dispel stigmas and misconceptions surrounding homeschooling while highlighting its diverse approaches and philosophies. Research objectives encompass evaluating reasons for choosing homeschooling, understanding its impact on children's educational, physical, mental, social, and emotional needs, and assessing overall satisfaction with the homeschooling …


Psychological Immunity Among Jordanian University Students During The Outbreak Of The Coronavirus Pandemic, Dalal Al-Samadi Sep 2025

Psychological Immunity Among Jordanian University Students During The Outbreak Of The Coronavirus Pandemic, Dalal Al-Samadi

Jordan Journal of Applied Science-Humanities Series

The purpose of the study was to investigate the level of psychological immunity and to determine whether there are statistically significant differences at the significance level (α = 0.05) in psychological immunity based on variables such as gender, academic specialization, and age among students of Jordanian universities during the outbreak of the coronavirus pandemic. To achieve the study's objectives, the researcher developed a scale to measure psychological immunity. The study sample consisted of 768 male and female students, selected by the convenience sampling method. The findings indicated a high level of psychological immunity among the students. Additionally, the results showed …


The Relationship Between The Level Of Optimism And The Performance Of Volleyball Players In The Premier League In The West Bank, Mahmoud Al-Atrash, Mosab Rashed Sep 2025

The Relationship Between The Level Of Optimism And The Performance Of Volleyball Players In The Premier League In The West Bank, Mahmoud Al-Atrash, Mosab Rashed

Jordan Journal of Applied Science-Humanities Series

The current study aimed to identify the relationship between the level of optimism and the performance of volleyball players in the Premier League in the West Bank. The researchers adopted a descriptive approach to suit the nature of the study. The sample consisted of 45 players, representing 42% of the original population. A measure of optimism, designed by the researchers after reviewing relevant educational literature and previous studies, was administered to the participants. To analyze the data, the researchers used One-Way ANOVA and T-tests. Among the most important findings was that the level of optimism among high-performing volleyball players in …


Salivary Matrix Metalloproteinase-7, Human Beta-Defensin 1, And Mucin-4 As Potential Diagnostic Biomarkers In Periodontal Disease: A Review, Haider Mohammed Shaloom, Omar Husham Ali Sep 2025

Salivary Matrix Metalloproteinase-7, Human Beta-Defensin 1, And Mucin-4 As Potential Diagnostic Biomarkers In Periodontal Disease: A Review, Haider Mohammed Shaloom, Omar Husham Ali

Maaen Journal for Medical Sciences

Periodontal diseases are a group of chronic, immune-mediated inflammatory conditions affecting the periodontium, the supportive structures of the teeth. With severe forms affecting nearly 20% of the worldwide adult population, these diseases represent a significant global health challenge. Their impact extends beyond the oral cavity, as periodontitis is a recognized risk factor for systemic conditions like cardiovascular disease and diabetes mellitus. Characterized by the progressive destruction of tooth-supporting tissues, early diagnosis is crucial to prevent tooth loss. However, conventional diagnostic methods primarily quantify historical tissue damage rather than indicating current disease activity or predicting future progression. To overcome these limitations, …


Thermal Spreader Materials On Flexible Polymer Substrates Sep 2025

Thermal Spreader Materials On Flexible Polymer Substrates

Defensive Publications Series

The present disclosure is generally directed to techniques and materials for thermal spreader materials, such as for use in products and applications with flexible polymer-based substrates


The Role Of Administration In Enhancing Community Partnership In Arab Schools In Beersheba Region, Ayman Abu Hajaj, Nouwar Al-Hamad Sep 2025

The Role Of Administration In Enhancing Community Partnership In Arab Schools In Beersheba Region, Ayman Abu Hajaj, Nouwar Al-Hamad

Jordan Journal of Applied Science-Humanities Series

The purpose of this study was to reveal the role of administration in enhancing community partnerships in Arab schools in Beersheba region from the school principals’ point of view. A descriptive survey approach was used to target the principals. The study sample intentionally consisted of all school principals in the region, totaling 100 principals from both genders. To collect data, a questionnaire consisting of 33 items was developed. Three independent variables were further investigated, namely: the school location, the principal's gender, and the principal's years of experience in the post. The results showed that the overall principals' estimate of the …


Logical Intelligence In Light Of The Prophetic Sunnah, Asma Bani Amer Sep 2025

Logical Intelligence In Light Of The Prophetic Sunnah, Asma Bani Amer

Jordan Journal of Applied Science-Humanities Series

This study focuses on an aspect related to the text of the Hadith, known as the subject-related Hadith. Specifically, it examines the Hadiths concerning what is called motor intelligence, in light of the Prophetic Sunnah. Modern education has paid attention to what is called multiple intelligences, including: bodily-kinesthetic intelligence, which is one of the forms of intelligence that emphasizes physical skills and athletic abilities. This aspect holds great importance in the Sunnah; therefore, the study aims to clarify the concept of motor intelligence, the extent of Islam’s concern with this aspect, and its most prominent expressions in light of the …


Evaluation Of Mobility And Functional Balance In Elderly Individuals With Type 2 Diabetes Based On Selected Kinematic Variables, Osama Abdel Fattah, Khaled Atiyat, Thamer Al-Manaseer Sep 2025

Evaluation Of Mobility And Functional Balance In Elderly Individuals With Type 2 Diabetes Based On Selected Kinematic Variables, Osama Abdel Fattah, Khaled Atiyat, Thamer Al-Manaseer

Jordan Journal of Applied Science-Humanities Series

This study aims to evaluate the kinematic indicators in the Timed Up and Go (TUG) test and the level of functional balance in the study sample according to the Berg Balance Scale. Additionally, it examines the relationship between BMI and the duration of diabetes with the values of kinematic indicators in the study sample in the TUG test and the level of functional balance on the Berg Balance Scale. Furthermore, it explores the relationship between the values of the kinematic indicators in the TUG test and the level of functional balance. To achieve this, the researchers employed a descriptive approach …


The Effectiveness Of Counseling Program Based On Adlerian Therapy To Improve Family Relations Among Battered Syrian Refugee Women, Rasha Husban, Fawwaz Ayoub Momani Sep 2025

The Effectiveness Of Counseling Program Based On Adlerian Therapy To Improve Family Relations Among Battered Syrian Refugee Women, Rasha Husban, Fawwaz Ayoub Momani

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the effectiveness of Adlerian treatment in improving family relations among battered Syrian refugee women. The study sample consisted of (30) Syrian refugee women from the city of Irbid, Jordan. The study sample was random. assigned to two groups: an experimental (15 women) and a control group (15 woman to achieve the study objectives, a family relations scale Manual (was used for the two groups, and a counseling program based on Adlerian therapy, developed by the researchers, consists of (14) sessions was applied to the experimental group. The results showed that the program was effective in …


What Next? A Challenging Case Of Refractory Hypertension With End-Organ Dysfunction In A 33-Year-Old Male, Rezane Miftari Md, Shaun Abid, Anton Stolear, Irma Fotjhadi Sep 2025

What Next? A Challenging Case Of Refractory Hypertension With End-Organ Dysfunction In A 33-Year-Old Male, Rezane Miftari Md, Shaun Abid, Anton Stolear, Irma Fotjhadi

Posters

We present a challenging case of a 33-year-old male with history of longstanding hypertension since high school, which progressed to RH complicated by severe left ventricular hypertrophy and hypertensive nephrosclerosis.


Library Lens September 2025, Southern Adventist University Sep 2025

Library Lens September 2025, Southern Adventist University

Library Lens

The September 2025 edition of Library Lens includes information on digital newspaper access, information literacy modules, Libby account updates, and Hispanic Heritage Month.


Volume 11 Issue 12 (Sept 1912) Sep 2025

Volume 11 Issue 12 (Sept 1912)

The Soul Winner

No abstract provided.


Toward A Unified Neuroaesthetic Framework For Art-Based Interventions In Substance Use Recovery - A Review, Piper Hutson, James Hutson Sep 2025

Toward A Unified Neuroaesthetic Framework For Art-Based Interventions In Substance Use Recovery - A Review, Piper Hutson, James Hutson

Faculty Scholarship

Art-based interventions have gained increasing recognition as complementary strategies for substance use disorder (SUD) recovery and prevention, yet the field remains fragmented across clinical art therapy, community-based programs, and expressive digital practices. This article advances a unified neuroaesthetic framework that integrates sensory regulation, narrative integration, and interpersonal synchronization as the core mechanisms of healing. Drawing on recent U.S.-based empirical studies (post-2020), the paper synthesizes evidence from multiple modalities, including visual arts, music therapy, dance/movement practices, and digital storytelling, each demonstrating measurable effects on craving reduction, stress regulation, identity reconstruction, and social connection. Neuroscientific insights are central: findings highlight how creative …


The Information Edge - Library Newsletter - September 2025, Sarah Burns-Feyl, Jennifer Rosenstein Sep 2025

The Information Edge - Library Newsletter - September 2025, Sarah Burns-Feyl, Jennifer Rosenstein

University Library Newsletter

No abstract provided.


Learning In Virtual Environments With Varying Levels Of Sensory Information, Maryam Derayati Far Sep 2025

Learning In Virtual Environments With Varying Levels Of Sensory Information, Maryam Derayati Far

Psychology Theses and Dissertations

The sensory environment plays a critical role in shaping learners’ attention, engagement, and retention. This thesis investigates how varying levels of sensory input in virtual reality (VR) classrooms influence learning for two age groups—children and young adults—and explores how individual differences in sensory processing moderate these effects. Using immersive VR technology to simulate classroom settings, two experimental studies were conducted. Study One involved 60 children aged 6–15 years, recruited primarily through a university-run summer camp. Study Two included 57 undergraduate students aged 18–36 years, recruited through a research participation pool. In both studies, participants were randomly assigned to either a …


Dentistry Likely To Be Affected By Developments Of A Legal Nature, Lance Plunkett Jd, Llm Sep 2025

Dentistry Likely To Be Affected By Developments Of A Legal Nature, Lance Plunkett Jd, Llm

The New York State Dental Journal

A few new legal developments that affect dentistry have taken place in recent months. Prominent among these is a Big Beautiful Bill that may not be so pretty for New York State.


Gaming As Therapeutic Modality For Military Veterans: Evidence, Mechanisms, And Program Design, Piper Hutson, James Hutson Sep 2025

Gaming As Therapeutic Modality For Military Veterans: Evidence, Mechanisms, And Program Design, Piper Hutson, James Hutson

Faculty Scholarship

This study synthesizes interdisciplinary evidence on game-based interventions for military veterans, mapping neurological mechanisms to clinically relevant outcomes while outlining design principles for community programs that leverage interactive media. The review characterizes how structured gameplay supports emotional regulation through attentional control, predictable feedback schedules, and reward-mediated learning that elevates motivation and mood; links to dopaminergic signaling and reduced rumination suggest plausible pathways for affective stabilization. Executive functions receive targeted engagement via strategy, puzzle, and action mechanics that demand working memory, cognitive flexibility, inhibition, and rapid decision-making, providing ecologically valid practice with measurable transfer to daily functioning. Social architectures in multiplayer …


Secondhand Smoke Exposure Among United States Children With Functional Disabilities: National Health And Nutrition Examination Survey, 2021–2023, Raed A. Bahelah Sep 2025

Secondhand Smoke Exposure Among United States Children With Functional Disabilities: National Health And Nutrition Examination Survey, 2021–2023, Raed A. Bahelah

Population Health Science Publications

Objective

Secondhand smoke exposure (SHSe) poses significant health problems. This study aims to examine the prevalence and factors associated with SHSe among 5–17 years old U.S. children with functional disabilities.

Methods

NHANES 2021–2023 applied Child Functioning Module to assess functional disabilities among 5–17 years old U.S. children. SHSe was defined as living in the same household with a person who is a tobacco smoker.

Results

Over three million (32.9 %) children with functional disabilities were exposed to SHS. Children with functional disabilities had higher odds of SHSe compared with children without functional disabilities (Adjusted Odds Ratio “AOR” =1.79, 95 % …


Progressive Insights Into 3d Bioprinting For Corneal Tissue Restoration, Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat Sep 2025

Progressive Insights Into 3d Bioprinting For Corneal Tissue Restoration, Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat

Michigan Tech Publications

The complex architecture of the cornea, characterized by specifically organized collagen fibrils and distinct cellular layers, poses significant challenges for traditional tissue engineering strategies to replicate its native function. 3D Bioprinting offers a promising solution by enabling the precise, layer-by-layer fabrication of corneal tissues, closely mimicking the essential characteristics needed for vision restoration and long-term graft success. This Review critically examines the key biomechanical, optical, and structural attributes of the cornea necessary for its effective engineering and accurate 3D bioprinting. It provides a comprehensive overview of different 3D bioprinting modalities utilized for corneal tissue engineering and offers insights into potential …


September 2025, Office Of Research Sep 2025

September 2025, Office Of Research

Research Update

No abstract provided.


Teaching Information Literacy In The Emerging And Dynamic Fields Of Preparedness And Security, Abigail Adams Sep 2025

Teaching Information Literacy In The Emerging And Dynamic Fields Of Preparedness And Security, Abigail Adams

University Libraries Faculty Scholarship

Emergency preparedness and security are comparatively new academic fields, but they have grown tremendously in the last ten years.1 Colleges and universities all over the United States and Canada are adding and expanding programs dedicated to various facets of these subjects. While the specific subtopics and focal areas can vary by program, they all explore threat assessment, risk management, and disaster mitigation in some capacity. Emergency preparedness or emergency management programs prepare students to pursue careers dealing with crisis mitigation and response, whether that crisis is a result of natural disaster, climate change, war, civil unrest, infrastructure failure, economic instability, …


Leveraging The Federal Trust Responsibility To Safeguard Net Neutrality On Tribal Lands, Morgan O. Schaack Sep 2025

Leveraging The Federal Trust Responsibility To Safeguard Net Neutrality On Tribal Lands, Morgan O. Schaack

University of Chicago Law Review

The internet plays a crucial role in modern life, but equal access to it is not guaranteed. This inequality is only starker since the recent overruling of the Chevron doctrine that afforded agencies deference in their interpretation of statutes and the second Trump administration’s hostility toward net neutrality––a policy that prevents internet service providers from charging more money for access to faster internet while slowing other users’ access. For those living on tribal lands, rescission of net neutrality policies has unique implications due to the federal government’s trust responsibility to American Indians.

The trust responsibility is a long-standing and deeply …


September 2025 Full Issue Sep 2025

September 2025 Full Issue

NASIG Newsletter

No abstract provided.


One Hundred Ninety-Nine Dead Birds: Review Of The Scientific Basis Of Ecological Incident Reporting Requirements For Pesticide Registrants Under Fifra § 6(A)(2), Nimish B. Vyas, Cynthia Palmer Sep 2025

One Hundred Ninety-Nine Dead Birds: Review Of The Scientific Basis Of Ecological Incident Reporting Requirements For Pesticide Registrants Under Fifra § 6(A)(2), Nimish B. Vyas, Cynthia Palmer

Buffalo Environmental Law Journal

The U.S. Environmental Protection Agency (EPA) regulates pesticide use in the United States. The EPA is charged by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) with ensuring that a pesticide will not cause unreasonable adverse effects on the environment. Incident reports (documentation of exposure and injury from pesticide applications) can serve as a reality check on the pesticide registration decisions made by the EPA scientists and risk managers. The EPA collects incident reports on human, domestic animal, and ecological injury. The FIFRA section 6(a)(2) rule requires the pesticide registrant (generally, the company or other entity that wishes to market …


Manatees In Hot Water: How The Florida Manatee Became Dependent On Power Plant Warm Water Outfalls, Michaela Morris Sep 2025

Manatees In Hot Water: How The Florida Manatee Became Dependent On Power Plant Warm Water Outfalls, Michaela Morris

Buffalo Environmental Law Journal

Each winter in Florida, thousands of manatees gather in the warm water outflows of power plants. These refuges play a crucial role for the Florida manatee: when ocean temperatures drop, manatees shelter at these artificial sources to survive. But in recent years, thousands of manatees wintering at the Florida Power & Light Company’s Cape Canaveral Clean Energy Center have died. The reason? Seagrass beds––a primary food source for manatees––are vanishing, killed off by pollution from agricultural, industrial, and residential sources.

This Article documents the historical, political, and regulatory conditions that led to manatees’ reliance on power plants. First, the political …