Digital Commons Network^™

Detection Of Heterogeneous Resistance Mechanisms To Tyrosine Kinase Inhibitors From Cell-Free Dna, Heather A Parsons, Conor Messer, Katheryn Santos, Jakob Weiss, David Merrell, Brian P Danysh, Melissa E Hughes, Gregory J Kirkner, Ashka Patel, Julian Hess, Kerry Sendrick, Chip Stewart, Elizabeth Grant, Kristy Schlueter-Kuck, Albert Grinshpun, Nikhil Wagle, Jamunarani Veeraraghavan, Jose Pablo Leone, Rachel A Freedman, Otto Metzger, Rachel Schiff, Eric P Winer, Sara M Tolaney, Mothaffar Rimawi, Ian E Krop, Gad Getz, Nancy U Lin

Faculty, Staff and Students Publications

Though there has been substantial progress in the development of anti-human epidermal growth factor receptor 2 (HER2) therapies to treat HER2-positive metastatic breast cancer (MBC) within the past two decades, most patients still experience disease progression and cancer-related death. HER2-directed tyrosine kinase inhibitors can be highly effective therapies for patients with HER2-positive MBC; however, an understanding of resistance mechanisms is needed to better inform treatment approaches. We performed whole-exome sequencing on 111 patients with 73 tumor biopsies and 120 cell-free DNA samples to assess mechanisms of resistance. In 11 of 26 patients with acquired resistance, we identified alterations in previously …

2025-08-25 Executive Council Minutes, St. Mary's University

Executive Council Minutes

No abstract provided.

Aku Postgraduate Medical Education Conference 2016

University press releases and calendars

No abstract provided.

Mixed-Methods Evaluation Of A Digital Resource For Interdisciplinary Delirium Education In Ireland, Gary Mitchell, Christine Brown Wilson

International Nursing Research Congress (INRC)

Background: Delirium is a common, underdiagnosed symptom of acute illness that can be prevented through early recognition and intervention. There is limited understanding of effective delirium education for pre-registration health students, and no evidence-based interdisciplinary digital resources exist. Using mixed methods, this study evaluates a co-designed digital tool for health students in Ireland to enhance their ability to prevent, identify, and manage delirium collaboratively [1-3].

Methods: Phase 1 assessed health profession students’ knowledge and self-efficacy in managing delirium through validated pre- and post-intervention questionnaires, including the Delirium Knowledge Questionnaire and a self-efficacy measure. Usability was evaluated using the System Usability …

Improving Student’S Attitudes, Perceptions, And Comfort Caring For Patients With Disabilities, Tina Truong, Elise Thompson

International Nursing Research Congress (INRC)

Purpose statement: The purpose of this project was to evaluate the impact of a two-week intensive curriculum on the perception, attitudes, and comfort of medical students towards people with disabilities (PWD).

Background: PWD represent the largest legally protected minority that experiences health disparities in the United States (US)⁽¹⁾. Healthcare providers (HCP) receive inadequate education to support this growing population⁽²⁾. In 2021, only 40.7% of surveyed physicians (MDs) reported confidence in their ability to provide the same quality of care to PWD as to those without and only 56.5% strongly agreed that PWD were welcome to seek …

Creation, Implementation, And Evaluation Of Authentic Virtual Reality Interprofessional Simulations, Kathleen Huun, Linda Mcquiston, Renee Bauer, Andreas Kummerow

International Nursing Research Congress (INRC)

Creating and implementing interprofessional (IP) simulations in undergraduate healthcare education fashions opportunities for students to understand their roles in a collaborative team and enhance their confidence (Kleib et al., 2021). Disciplines may coalesce their knowledge, skill sets, and collective evidence-based practice to address multifaceted patient care.

An effective simulation modality to heighten practice readiness is virtual reality (VR) (Phillips et al., 2023). Immersion through a 3D platform provides visualization and interaction in a supposed real world (Cieslowski, 2023) for students to maneuver in while void of distractions. This intense focus facilitates critical thinking and clinical decision-making (Baysan et al., 2023). …

Validity And Reliability Of The Mongolian Version Of Functional Assessment Of Cancer Therapy, Gelegjamts Gelgersuren, Gaalan Khulan, Kim Jin Sun

International Nursing Research Congress (INRC)

Background: The health-related quality of life (HRQOL) is an important indicator for determining the health outcomes of cancer treatment. The Functional Assessment of Cancer Therapy-General (FACT-G) scale, which was developed in the USA and validated in many countries, is widely used to measure the HRQOL in cancer patients. In Mongolia, there is no valid and reliable instrument to measure HRQOL for cancer patients. The purposes of this study was to empirically validate the FACT-G scale with Mongolian cancer patients.

Methods: This study was a methodological study. The English version of FACT-G was translated into the Mongolian language using the Functional …

The Effect Of Trauma-Informed Care (Tic) Training Among Trauma Staff And Patient Satisfaction, Cristal Vieyra-Poston

International Nursing Research Congress (INRC)

Background: Patients and staff have unique pasts, often consisting of adverse childhood events and/ or current social challenges that affect how people, interactions, and events are processed. Increasing staff complaints were observed about challenging patients’ behaviors, resulting in some staff not wanting to care for these patients. There was a lack of awareness and understanding not only about the nature of traumatization and how it manifests in people with maladaptive coping, but also staff’s own trauma triggers that can lead to secondary trauma, compassion fatigue, burnout, and even depression (Stokes et al., 2017).

Method: The project used the evidence-based 8A’s …

A Pilot Acceptability Trial Of A Prototype Robotic Assistive Device In An Acute Care Setting, Mimia Cynthia Logsdon, Irina Kondaurova, Payman Sharafianardakani, Mandi Walker, Heather Mitchell, Nancy Zhang, Branden Shay, Daniel O. Popa

International Nursing Research Congress (INRC)

BACKGROUND: If acceptable to users, technological innovations including robotic assistive devices have the potential to promote patient safety (fall prevention) and enhance nurse’s time management. The Technology Acceptance Model (TAM) explains how users accept new technology;¹ two primary constructs, Perceived Usefulness (PU) and Perceived Ease of Use (EU), predict Behavioral Intentions (BI) and eventual use of technology with Satisfaction (S) added later as an outcome variable.²

Purpose: Guided by TAM, conduct a pilot acceptability trial of a prototype robotic assistive device (ARNA).

METHODS: Using convenience sampling in US urban acute care setting, study participants included patients …

Cloud-Based Hybrid Training: Bridging International Nurses' Competency For Us Healthcare, Jose Arnold Tariga, Lisa Mceathron, Christian Striggow

International Nursing Research Congress (INRC)

Background: The increasing global migration of internationally educated nurses (IEN) underscores the need for effective transition programs to bridge competency gaps across international nursing standards. IENs preparing to enter the US healthcare system face challenges in adapting to new practices and technologies. To address these gaps, a hybrid International Transition to Practice Program was developed, integrating cloud-based simulation technology and immersive learning to enhance clinical readiness.

Methods: This 16-week hybrid program combined didactic instruction, skill-based training, and simulation-based education (SBE). A cloud-based simulation platform enabled real-time interaction between US-based educators and learners in the Philippines. In 2024, 39 immersive simulations …

Faculty-Led Student Mentoring: Student And Faculty Perspectives, Stephanie Dunn, Jill Johnson, Halie J. Hansen, Francine Jensen

International Nursing Research Congress (INRC)

Purpose Statement: This presentation shares nursing student and faculty perspectives on faculty-led mentoring for prelicensure students. Results of a student needs assessment survey, combined with faculty feedback, informed program components and can guide other nursing schools globally in starting mentoring programs.

Abstract: The demands on prelicensure nursing students in today’s fast-paced and often stressful academic environment can feel overwhelming. Students must adapt to new educational phases and prepare to provide exceptional patient care. Mentoring has been widely recognized in educational literature as an effective strategy to enhance performance, improve retention, and foster overall student success (5). While extensive …

Impact Of Technology On Physical Activity Levels Of Pediatric Cancer Survivors: A Systematic Review, Aylin Akca Sumengen, Eysan Hanzade Savas, Ayse Ay, Ilcim Ercan Koyuncu, Munevver Erkul, Remziye Semerci

International Nursing Research Congress (INRC)

Background: Pediatric cancer survivors often face long-term health challenges such as muscle weakness and obesity [1, 2, 3]. Physical activity is essential for lessening these effects, and technological interventions have been suggested to promote physical activity among pediatric cancer survivors [3, 4].

Purpose: This systematic review aimed to evaluate technological interventions' impact on pediatric cancer survivors' PA levels.

Methods: The systematic review followed PRISMA guidelines [5] and included studies published until May 2024 from various databases. The Joanna Briggs Institute (JBI) critical appraisal tools were used to assess study quality. The study was registered in PROSPERO under registration …

Float Nurses’ Association With Nurse Sensitive Indicators: A Cross-Sectional Study, Catherine Stephens, M. Terese Verklan, Juanita Norton, Danielle Walker

International Nursing Research Congress (INRC)

Nurse staffing plans that are flexible and adaptable can enhance the resilience of healthcare organizations, ensuring that they are better equipped to meet the fluctuating needs of patients.¹ Floating is a common flexible nurse staffing strategy, yet its effects on nurse-sensitive indicators (NSIs) remain largely unexplored. Nurses have expressed concerns about floating and patient safety.^2-3 Floating unit-based nurses are associated with increased occupational stress^2-6 and burnout,⁵ which can act as mental distractions impacting NSIs.⁶ The study aimed to evaluate the effects of two distinct forms of floating: nurses from dedicated float pools and unit-based nurses …

Transition To Home For Children With Medical Complexity: Insights From A Scoping Review, Christine Rae Platt, Emily F. Moore, Cara Gallegos, Mia Waldron, Barbara Giambra, Stacee Lerret, Danielle Sarik, Zara Sajwani-Merchant, Nesibe Sumeyye Kutahyalioglu, Pamela Gampetro, Susan L. Groshong, Marianne Weiss, Terri Hernandez, Sandra Staveski

International Nursing Research Congress (INRC)

Purpose: Discharge readiness for the transition from hospital to home for medically complex children (MCC) involves both clinical stability of the child and comprehensive preparation of parents. This challenging period can be marked by significant risk and stress. Nursing teams play a critical role in providing discharge planning, teaching, and care coordination during this pivotal time. We aimed to identify key nurse-driven components of effective discharge preparation, and gaps requiring further research, to improve the transition from hospital to home in MCC.

Methods: Team members, including 12 PhD prepared nurses from the National Pediatric Nurse Scientist Collaborative, undertook a systematic …

Delivery Of Expedited Partner Therapy For Sexually Transmitted Infections Among Women In Kenya, Jerusha Nyabiage Mogaka, Tessa Concepcion, Felix Abuna, Eunita Akim, Melissa Mugambi, Helen Aketch, Sarah Obatsa, John Kinuthia, Kenneth Ngure, Kristin M. Beima-Sofie, Grace C. John-Stewart, Jillian Pintye

International Nursing Research Congress (INRC)

Background: Expedited partner treatment (EPT) for sexually transmitted infections (STIs) prevents re-infection and is recommended by the World Health Organization to reduce STI transmission.^1,2 Yet, limited data exist on women’s experiences with EPT and their STI outcomes following EPT dispensation. We evaluated EPT outcomes and perspectives among women with recent STIs who were offered EPT in Kenya.

Methods: Women enrolled in a randomized trial at 5 antenatal clinics in Western Kenya (NCT04472884) were tested for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in pregnancy and/or postpartum as part of study procedures. ^3-5 Women testing positive were offered …

What’S In A Name?: Transgender People’S Affirming And Invalidating Experiences With Preferred Names, Narciso Quildey-Rodriguez

International Nursing Research Congress (INRC)

Transgender and nonbinary (TNB) people’s gender identity differs from the sex they were assigned at birth. Approximately 1.6 million people identify as TNB in the US. Affirmation, the process of acknowledging a person’s gender identity, plays a significant role in the mental health and well-being of TNB people by reducing feelings of isolation, dysphoria, and anxiety. Invalidation, which occurs when a person’s gender identity is denied, can have significant adverse effects on the mental and emotional well-being of TNB people. This presentation explores TNB people's affirmative and invalidating experiences related to using preferred names and pronouns. Twenty semi-structured interviews with …

Caring For A Child With A Tracheostomy At Home: A Photovoice Study, Julie Van Orne, Kia Mccoy

International Nursing Research Congress (INRC)

The population of children with a tracheostomy (trach) continues to grow as technological advancements have shifted how care is provided to children born with complex conditions, including more of them being offered a trach to prolong life.¹ Home-based supportive services for children with a trach are underfunded and understaffed, putting the onus of care on the child’s family.² The daily life of caregivers of these complex children has not been well documented.³ The home is an intimate and person-specific space with its own context, patterns of relationships, power structures, and rules that are uniquely different from other …

A Systematic Review Of Artificial Intelligence And Nursing Education: What Do We Know?, Rayhanah R. Almutairi

International Nursing Research Congress (INRC)

Problem: Artificial intelligence (AI) has driven a global change in nursing education and is becoming more prevalent worldwide. Integrating AI into nursing education could revolutionize the preparation of future nurses and equip them with the necessary knowledge and skills related to AI. However, the existing literature on the intersection of nursing education and artificial intelligence is sparse, consisting primarily of commentaries, editorials, and opinion articles. To our knowledge, there is a notable gap in the comprehensive review that systematically synthesizes the current use of AI in nursing education.

Purpose: The aim of this systematic review was to synthesize the body …

Detecting Bad Actors In Social Media Research Recruitment: Ai And Bots, Oh My!, Sarah E. Patel, Steven R. Chesnut

International Nursing Research Congress (INRC)

Purpose: Researchers can use social media to recruit diverse populations for research studies with targeted posts in groups and across platforms with marketing. Sadly, Meta estimates 3% of the active 3.07 billion Facebook accounts are fake. Fake accounts that use bots and artificial intelligence (AI) threaten the integrity of research findings. Unfortunately, no guidelines exist to help researchers identify bad actors, or individuals not engaging with a survey in good faith via bots or AI assistance. We discuss our strategies to detect and remove bad actors.

Methods: We recruited participants from a Facebook pelvic congestion syndrome support group …

Global Learning Innovation: Addressing The Sdgs In An Interprofessional Partnership In Cyprus, Dianne Morrison-Beedy

International Nursing Research Congress (INRC)

Background/Purpose: Recognizing the importance of interprofessional educational experiences and graduating global citizens, nursing must think creatively to develop learning opportunities for global interaction. Challenges exist in offering study-abroad nursing experiences as curriculums are very full, controlled for content, and oftentimes accelerated. Building interdisciplinary collaborations outside of health may provide an untapped, innovative opportunity for building partnerships to enhance global educational outcomes. This presentation describes a unique partnership between nursing and geography designed to develop students’ understanding of the Sustainable Development Goals (SDGs) from diverse perspectives.

Methods: Our brief study abroad experience in Cyprus integrated joint field immersion experiences focused …

Prioritizing New Nurse Well-Being: Factors Affecting Patient Safety, Errors, And Turnover, Cory D. Church, Seungman Kim

International Nursing Research Congress (INRC)

Purpose: The well-being of new nurses influences individual health and organizational performance, including job satisfaction, turnover intent, and patient safety (NASEM, 2019). In the global healthcare landscape, addressing these concerns is essential for promoting leadership in organizational development. This study explores the relationship between the well-being of new nurses and organizational outcomes, focusing on leadership strategies that enhance well-being and improve healthcare system functionality.

Background and Significance: New nurses face significant challenges transitioning into professional practice. Transition shock, experienced by new nurses within their first 18 months of practice, leads to stress and burnout (Duchscher, 2018; Eckerson, 2018). Healthcare systems …

Re-Fracture Within One Year After Hip Fracture Surgery In The Elderly And Its Related Factor, Shuwen Cheng, Tsae-Jyy Wang

International Nursing Research Congress (INRC)

Background and Purpose Hip fracture is the most common cause of trauma admissions in the elderly. The incidence of contralateral hip fracture after hip fracture in the elderly is 10.8%, resulting in more disability, mortality, and increased medical cost. The study is to investigate the incidence of re-fracture in the elderly and possible related factors, including demographics, fracture types and treatments, osteoporosis parameters, lifestyle, body mass index, comorbidities, and clinical visits.

Methods This is a retrospective study. Data were collected from chart reviews of older adults who received hip fracture surgery at a hospital in Taiwan between 2018 and 2021. …

The Effectiveness Of Medical-Grade Honey Towards Burning Wound Healing: An Evidence-Based Approach, Ting-Ting Yang, Hsiang-Chu Pai

International Nursing Research Congress (INRC)

Background: According to World Health Organization, there are approximately 18,000 people die due to burns around the world every year. Burns often lead to prolong hospitalization, affect outlooks, increase treatment cost, and even disability. Besides, people might reject the burning patients owing to their appearance which could also affect their mental health.

There was a burning patient received the standard wound care method, then put on medical-grade honey gel with foam dressing, and it gradually helped wound healing.

Literature Review: After reviewing literature with PICO in different databases (e.g., Medline, PubMed and Cochrane), which P refers to burning wound, I …

Bridge-Icu: A Novel Approach To Reducing Futile Care Through Early Goal Alignment In Critical Care, Bryan Frankovitch, Kristin Bott, Joy Elwell, Anna-Rae Montano

International Nursing Research Congress (INRC)

Futile care in critical care settings creates ethical dilemmas and places emotional, physical, and financial burdens on patients and healthcare systems. The BRIDGE-ICU algorithm was developed to address these challenges by aligning ICU interventions with patient prognosis and goals-of-care early in the ICU admission process. This quality improvement project, conducted in a 12-bed medical ICU, aimed to reduce the incidence of non-beneficial care through interdisciplinary collaboration and early structured conversations. Patients flagged for potentially futile care were identified by the interdisciplinary care team based on clinical indicators and prognosis. Data collected over two months showed a significant 22.69% reduction in …

Improving Collaboration And Data Storage At An Ihs Facility: Kotter’S Method Of Organization Change, Madison Spellman, Dwight Kappl

International Nursing Research Congress (INRC)

Purpose: Inefficient communication and knowledge sharing have been linked to delayed patient care and reduced staff collaboration¹. The integration of applications for healthcare communication and knowledge storage² can improve clinic efficiency and staff communication³.

Documents and data at an IHS facility are stored on the clinic’s Z-Drive: a collection of folders on a clinic server containing outdated documents. If a staff member is editing a shared document in the Z-Drive, another staff member cannot also be editing the same document. If staff do not save a document correctly, multiple copies of the same document can …

Enhancing Pediatric Stoma Nursing Care: Analyzing Youtube Videos For Pediatric Stoma Care Techniques, Aylin Akca Sumengen, Inci Kirtil, Damla Ozcevik Subasi, Gokce Naz Cakir, Gozde Turkmenoglu Kucukakca

International Nursing Research Congress (INRC)

Background: Stoma care requires a multidisciplinary team, but when the patient is a child, family-centered care is crucial [1, 2, 3]. Caregivers and patients without prior experience in ostomy care often share their experiences and seek answers to their questions on digital platforms like social media and YouTube [3, 4]. YouTube is considered a valuable resource for educating pediatric patients and parents. It provides interactive and visual education, which is more accessible than traditional written materials [4, 5, 6]. However, it's important to assess the reliability and validity of these videos through content analysis.

Purpose: The purpose of this study …

Nursing Pedagogy: Using Gaming For Multifaceted Knowledge And Skills For Emotional Intelligence, Ashley Lanai Harmon, Jill Jackson Van Der Like

International Nursing Research Congress (INRC)

The current academic climate shows that students entering nursing school do not have the emotional mindset that will allow them success and longevity post-graduation in nursing (Budler et al., 2022; Christianson, 2020; Cleary et al., 2018; Crawford et al., 2021; Dugué et al., 2021) . Students often struggle through their program, with clinical and didactic or either independently in relation to academic success or performance. Additionally, once these students pass their NCLEX exam, they tend to find themselves overwhelmed and emotionally unable to withstand the pressures of floor nursing. As of 2024, research has shown that nationally, about 31% of …

Effects Of Exercise Program On Symptom And Psychological Distress In Frail Cardiac Surgery Patients, Li-Kai Cheng, Ai-Fu Chiou

International Nursing Research Congress (INRC)

Background: Postoperative cardiac surgery patients often experience symptoms such as chest pain, poor sleep, depression, and anxiety. Healthcare providers need to identify effective interventions to alleviate these physical and psychological issues.

Objectives: This study evaluated the impact of a multidimensional exercise program on symptom and psychological distress in frail patients after cardiac surgery.

Methods: A randomized controlled trial was conducted with 88 cardiac surgery patients from two medical centers in northern Taiwan. Patients were randomly assigned to the intervention group (n = 45) or control group (n = 43). The intervention group participated in a 12-week multidimensional exercise program, which …

Cross-Cultural Adaptation And Validation Of Social Abuse Scale In South Korea And Turkey, Kader Tekkas-Kerman, Sihyun Park

International Nursing Research Congress (INRC)

Background: Intimate partner violence (IPV) is a pervasive issue worldwide (United Nations, 2024). Various forms of IPV have been investigated (Henry et al., 2021), including the recently explored concept of social abuse. Social abuse refers to the intentional act of violating an individual’s rights and needs for social belonging within an intimate relationship (Park & Jeon, 2022). These actions can lead to a myriad of negative effects on the victims’ mental health and social relationships, as well as result in the victims’ social isolation (Stoff et al., 2021). Recently, we have developed an English version of the Social Abuse …

Examining Latent Class Variations In Adult Women Diagnosed With Pelvic Congestion Syndrome, Sarah E. Patel, Steven R. Chesnut

International Nursing Research Congress (INRC)

Purpose: Pelvic pain is a classic textbook symptom of pelvic congestion syndrome (PCS). Historically, PCS pain has been described as dull and achy. Yet, women’s PCS pain experience and description may differ from classic textbook presentations. In recent work, women’s PCS pain profiles are either intense and debilitating or mild but consistent. Women in the intense and debilitating group reported pain as intense, unbearable, sharp, stabbing, shooting, sickening, and exhausting, while women in the mild but consistent class reported pain as nagging, troublesome, tiring, aching, and pressing. These differences may explain variability between groups of women with PCS …