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Articles 59161 - 59190 of 1791792
Full-Text Articles in Entire DC Network
Raphael Say Dan Non-Toxic Masculinity Dalam Dunia Mode Prancis, Layyina Arifah Shabira, Airin Miranda
Raphael Say Dan Non-Toxic Masculinity Dalam Dunia Mode Prancis, Layyina Arifah Shabira, Airin Miranda
Multikultura
Non-Toxic Masculinity kini menjadi wacana penting dalam merespons maskulinitas tradisional yang kaku dan menekan. Penelitian ini menganalisis bagaimana Raphaël Say, model dan influencer asal Prancis, merepresentasikan bentuk maskulinitas yang lebih inklusif dan gender-fluid melalui platform media sosial Instagram dan TikTok. Dengan menggunakan Analisis Wacana Kritis oleh Fairclough (1995), Semiotika Roland Barthes (1957), dan Teori Performativitas Judith Butler (1990), analisis ini mengungkap bagaimana Raphaël Say membangun narasi maskulinitas baru yang ekspresif, lembut, dan menantang norma gender hegemonik. Melalui visual, gaya berpakaian, bahasa tubuh, serta narasi digital yang ia tampilkan secara konsisten, Say memanfaatkan media sosial sebagai ruang resistensi terhadap konstruksi gender …
Exploring Local Residents’ Response To Ecological Resettlement Policy: A Tpb-Based Study In Zhalong National Nature Reserve, Zhi Wang
Double Helix Methodology
Studies on residents' ecological conservation behaviors primarily focus on personal and socio-economic factors, neglecting crucial psychological aspects like intentions and perceptions. To address this gap, this study investigates the implementation of the ecological resettlement policy in the Zhalong Nature Reserve in northeast China, analyzing how residents respond to it using the Theory of Planned Behavior as the analytical framework. Drawing on survey data, the study quantitatively assesses the influence of residents’ attitudes, subjective norms, and policy evaluations on their behavioral intentions. The results reveal that higher evaluation of ecological resettlement policy promotes policy adoption. Attitudes towards policy positively influence intentions, …
Law, Labor, And Identity, Chantal Thomas
Law, Labor, And Identity, Chantal Thomas
Law and Contemporary Problems
No abstract provided.
Towards A Reconstructive Politics, K. Sabeel Rahman
Towards A Reconstructive Politics, K. Sabeel Rahman
Law and Contemporary Problems
No abstract provided.
Atypical Abdominal Pain: Uncovering Malignant Peritoneal Mesothelioma In Suspected Crohn's Disease: A Case Report, Catherine Loehr, Lara Boudreaux, Ann Porter Uhlhorn, Nisha Loganantharaj
Atypical Abdominal Pain: Uncovering Malignant Peritoneal Mesothelioma In Suspected Crohn's Disease: A Case Report, Catherine Loehr, Lara Boudreaux, Ann Porter Uhlhorn, Nisha Loganantharaj
School of Medicine Faculty Publications
BACKGROUND: Malignant peritoneal mesothelioma (MPM) is a rare and aggressive cancer from the serosal membranes of the abdominal cavity. In the United States, MPM accounts for about 10-15% of all mesothelioma cases, and translates into approximately 600 new cases diagnosed annually. It is typically diagnosed in Caucasian individuals, and while asbestos exposure is a well-established risk factor for pleural mesothelioma, its association with peritoneal mesothelioma remains less clear. Clinical symptoms of MPM, such as abdominal pain, bloating, and weight loss, overlap with other gastrointestinal disorders, which often leads to delayed diagnosis. This case report presents a unique instance of MPM …
Assessment Of Vector Control Strategies Based On Mass Aedes (Stegomyia) Mosquito Trapping (Agos Traps) Pilot Study In A Us-Mexico Border Region Of South Texas, Jesús A. Aguilar-Durán, Josue Ramírez, Mario A. Rodríguez-Pérez, Christopher J. Vitek, Nadia A. Fernández-Santos, José Guillermo Estrada-Franco
Assessment Of Vector Control Strategies Based On Mass Aedes (Stegomyia) Mosquito Trapping (Agos Traps) Pilot Study In A Us-Mexico Border Region Of South Texas, Jesús A. Aguilar-Durán, Josue Ramírez, Mario A. Rodríguez-Pérez, Christopher J. Vitek, Nadia A. Fernández-Santos, José Guillermo Estrada-Franco
School of Integrative Biological & Chemical Sciences Faculty Publications
Background: Aedes (Stegomyia) aegypti and Ae. (Stegomyia) albopictus mosquitoes are major vectors of diseases including dengue, Zika, chikungunya, and yellow fever. The excessive use of chemical insecticides has caused resistance in mosquito populations, along with negative environmental impacts and harm to non-target organisms. In this regard, mosquito control strategies, such as passive mass trapping interventions with autocidal gravid ovitraps (AGO) offer a promising alternative. Here we report the results of a pilot study evaluating a passive mass trapping treatment using AGOs against Ae. aegypti in the city of Harlingen, Texas, USA, during the peak mosquito season.
Methodology: Three treatments were …
October 31, 2025 Minutes, Swosu Faculty Senate
October 31, 2025 Minutes, Swosu Faculty Senate
Faculty Senate Minutes
No abstract provided.
A Green Manufacturing Model: Joint Optimization Of Maintenance, Scheduling, And Sustainability, Ahmed Attia, Mohamed Darghouth, Ahmed Ghaithan, Awsan Mohamed, Noha Mostafa
A Green Manufacturing Model: Joint Optimization Of Maintenance, Scheduling, And Sustainability, Ahmed Attia, Mohamed Darghouth, Ahmed Ghaithan, Awsan Mohamed, Noha Mostafa
Mechanical Engineering
This study proposes an integrated framework for sustainable manufacturing that jointly optimizes production scheduling, maintenance planning, and carbon-conscious energy management. A Mixed-Integer Nonlinear Programming (MINLP) model is developed to minimize makespan while maintaining machine reliability and ensuring compliance with greenhouse gas (GHG) emission limits. The model incorporates speed scaling as a decision variable, capturing the trade-off between processing time, energy consumption, and machine degradation. Preventive maintenance (PM) and minimal repair (MR) strategies are explicitly modeled using a Weibull-based failure distribution, and a carbon cap constraint is introduced to bound total emissions. A case study demonstrates the model's practical relevance, and …
Understanding Tobacco Use Among Bangladeshi Men: A Socio-Demographic Analysis Of Risk Factors, Md. Rashedus Salekin Sabbir, Helal Uddin, Md Shazid Hossain Shohan
Understanding Tobacco Use Among Bangladeshi Men: A Socio-Demographic Analysis Of Risk Factors, Md. Rashedus Salekin Sabbir, Helal Uddin, Md Shazid Hossain Shohan
Indonesian Journal of Public Health Nutrition (IJPHN)
Tobacco consumption remains a major public health concern in Bangladesh, where adult males represent the most affected group. Despite existing bans on public smoking, cultural norms, media influence, and limited awareness continue to sustain high prevalence. The objective of this study was to examine the socio-demographic determinants of tobacco use among Bangladeshi men, focusing on regional variation, education, media exposure, and family influence. A cross-sectional survey was conducted among 275 adult males in Dhaka Division using a structured questionnaire. Data was analyzed through descriptive statistics, chi-square tests, and binary logistic regression to identify significant predictors of tobacco consumption. Findings reveal …
Proportion Of Chronic Energy Deficiency In Relation To Macronutrient Intake And Other Determinants Among Pregnant Women In Selected Community Health Center Service Areas In Bogor 2025, Fathimah Afliansa, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari, Suparno Suparno
Proportion Of Chronic Energy Deficiency In Relation To Macronutrient Intake And Other Determinants Among Pregnant Women In Selected Community Health Center Service Areas In Bogor 2025, Fathimah Afliansa, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari, Suparno Suparno
Indonesian Journal of Public Health Nutrition (IJPHN)
The prevalence of chronic energy deficiency (CED) among pregnant women in Indonesia remains relatively high, ranging from 11.6% to 57.6%. This study aimed to examine the differences in the proportion of CED based on macronutrient intake and related factors. The study used a quantitative cross-sectional design with secondary data involving 124 pregnant women in selected areas served by community health centers in Bogor City and Regency. Data were analyzed using the chi-square test. CED prevalence was 11.3% in the overall areas, with 10.9% in Bogor City and 11.7% in Bogor Regency. Significant differences in the CED proportion were found based …
Reframing Nutrition Policy For Under-Five Children In Thailand: Beyond The First 1,000 Toward 2,500 Days, Saipin Chotivichien, Waraporn Jitaree, Wareethip Phuengpan, Saiyed M. Hyder
Reframing Nutrition Policy For Under-Five Children In Thailand: Beyond The First 1,000 Toward 2,500 Days, Saipin Chotivichien, Waraporn Jitaree, Wareethip Phuengpan, Saiyed M. Hyder
Indonesian Journal of Public Health Nutrition (IJPHN)
Malnutrition continues to threaten child health globally, with Thailand mirroring this trend: in 2022, 12.4% of children under five were stunted, 7.2% wasted, and 10.9% obese. While the country’s First 1,000 Days initiative—targeting pregnancy to age two—yielded early success in reducing undernutrition, emerging gaps among 3–5-year-olds prompted a policy shift toward a broader 2,500-day framework. This approach, launched in 2022, extends care from preconception through age five and integrates multisectoral action involving five key ministries. Anchored in the “Power of Three Pillars”—policy, partnerships, and resources—the initiative strengthens local governance, enhances service delivery, and fosters family and community engagement through sub-district …
Mandating Fluoride: A Constitutional Exercise Of Police Power, Anita Jahangiri
Mandating Fluoride: A Constitutional Exercise Of Police Power, Anita Jahangiri
Seattle University Law Review
This Note addresses the ongoing debate over fluoridation: the regulation of fluoride levels in public water systems. Extensive research indicates fluoridation, when regulated at the recommended concentration, is both safe and highly effective in preventing dental caries. Better known as cavities, dental caries is a preventable yet widespread health issue that disproportionately affects low-income populations. Reducing dental health disparities among economic classes is a pressing public health issue. Fluoridation is not merely a policy option, but a critical, proven tool to address such disparities and uphold the collective welfare of Washingtonians. This Note focuses on fluoridation as a public health …
Neurodiversity In The Courtroom: Expanding Jury Service Accessibility Beyond Physical Disability, Samantha L. Mabe
Neurodiversity In The Courtroom: Expanding Jury Service Accessibility Beyond Physical Disability, Samantha L. Mabe
Seattle University Law Review
The Americans with Disabilities Act has required equal access to jury service for decades; however, efforts to accommodate jurors with disabilities have been slow to develop beyond some minor accommodations for physical disabilities. While neurodivergent people frequently struggle to navigate a world catered toward neurotypical people, jury service remains inaccessible for many neurodivergent people who need accommodations to attend trial and engage in jury deliberations. If courts and advocates do not consider how to develop accommodations to secure the service of neurodivergent jurors, they will miss out on the unique skillsets that neurodivergent people can bring to resolving disputes.
Disabled …
Sga 57 Senate 2025-10-31 Minutes, Niu Student Government Association Senate
Sga 57 Senate 2025-10-31 Minutes, Niu Student Government Association Senate
Student Government Association Archives
No abstract provided.
Safety And Efficacy Of Liver-Directed Radiotherapy After Chemoimmunotherapy For Advanced Cholangiocarcinoma: An Early Report From A Large Tertiary Cancer Center, Abdulmoiz Asif, Abdulmoid Asif, Michael K Rooney, Enoch Chang, Felicity Namayanja, Kimana Quentin, Sunyoung Lee, Ian Hu, Vincent Bernard, Prajnan Das, Emma B Holiday, Sonal Noticewala, Grace L Smith, Albert C Koong, Ethan B Ludmir, Milind Javle, Lianchun Xiao, Eugene J Koay
Safety And Efficacy Of Liver-Directed Radiotherapy After Chemoimmunotherapy For Advanced Cholangiocarcinoma: An Early Report From A Large Tertiary Cancer Center, Abdulmoiz Asif, Abdulmoid Asif, Michael K Rooney, Enoch Chang, Felicity Namayanja, Kimana Quentin, Sunyoung Lee, Ian Hu, Vincent Bernard, Prajnan Das, Emma B Holiday, Sonal Noticewala, Grace L Smith, Albert C Koong, Ethan B Ludmir, Milind Javle, Lianchun Xiao, Eugene J Koay
Faculty, Staff and Student Publications
BACKGROUND: Recent randomized controlled trials have established chemoimmunotherapy as the standard of care for patients with advanced biliary cancers with a median overall survival (OS) of about thirteen months. No data exist to demonstrate the safety and efficacy of liver-directed radiotherapy (RT) for extrahepatic and intrahepatic cholangiocarcinoma (CCA) in the era of chemoimmunotherapy. The purpose of this study is to report our early experience treating patients with CCA using RT and chemoimmunotherapy.
METHODS: Twenty-eight patients with CCA who received chemoimmunotherapy sequentially and/or concurrently with RT were retrospectively analyzed. The median biologic equivalent dose (BED) of RT was 84.0 [interquartile range …
Women’S Mba Peers Affect Their Course Choices, Career Paths, And The Gender Pay Gap, Mallika Thomas
Women’S Mba Peers Affect Their Course Choices, Career Paths, And The Gender Pay Gap, Mallika Thomas
Employment Research Newsletter
No abstract provided.
Reconnecting The Wetlands Through Non-Discrete Architecture, Aulia Rahman
Reconnecting The Wetlands Through Non-Discrete Architecture, Aulia Rahman
ARSNET
This design study explores non-discrete architecture as a form of architecture that connects nature and the built environment. Architecture often separates itself and its users from the natural setting, leading to environmental neglect and the gradual loss of
the natural environment. The idea of non-discrete architecture focuses on how the relationship between humans and nature can be reconstructed by creating spatial layers that can actively participate in living processes. This study focuses on the neglected wetland environment in Banjarmasin, South Kalimantan. The inquiry begins by documenting the various experiences of nature in the area, from the abundance presence of wilderness …
The Mosaic, Georgia Southern University
The Mosaic, Georgia Southern University
George-Anne Media Group: Newsletters & Magazines
No abstract provided.
Causal Predictive Modeling Of Survival Of Lung And Bronchus Cancer Patients Diagnosed During 2010–2011 In Texas, Zeinab Mohamed, Sidketa Fofana, Everardo Cobos, Manish K. Tripathi, Tamer Oraby
Causal Predictive Modeling Of Survival Of Lung And Bronchus Cancer Patients Diagnosed During 2010–2011 In Texas, Zeinab Mohamed, Sidketa Fofana, Everardo Cobos, Manish K. Tripathi, Tamer Oraby
School of Mathematical & Statistical Sciences Faculty Publications
Background: Lung and Bronchus cancer is the most fatal type of cancer in the United States. According to the American Cancer Society, there were more than 127,000 deaths from lung cancer in 2023. Lung cancer care cost 23.8 billion dollars in 2020. In Texas, only 22.8% of lung cancer patients survived 5 years or more past diagnosis based on 2012-2018 data.
Aim: This study evaluates the survival length of lung and bronchus cancer patients in Texas using advanced statistical and machine learning methods applied to an 11-year cohort study from Surveillance, Epidemiology, and End Results Program. It also quantifies the …
Discourses On Pregnancy In Old Javanese Śaiva Texts From The Perspective Of Kawi Culture, Putu Eka Guna Yasa, Ida Bagus Arya Lawa Manuaba, I Wayan Cahyadi Surya Distira Putra
Discourses On Pregnancy In Old Javanese Śaiva Texts From The Perspective Of Kawi Culture, Putu Eka Guna Yasa, Ida Bagus Arya Lawa Manuaba, I Wayan Cahyadi Surya Distira Putra
Wacana, Journal of the Humanities of Indonesia
This article examines the discourse on pregnancy in the context of Kawi culture. The sources of data discussed here include texts of Śaiva persuasion across various genres and geographical areas, such as the Old Javanese Bhīṣmaprava from the Merapi-Merbabu region, the Old Javanese Bhīma Svarga from West Java, and a number of Old Javanese and Balinese texts from Bali, namely Tutur Aṅgastya Prāṇa, Śivāgama, Tutur Kanda Pat Bhūta, Dharma Kahuripan, and Uṣadha Mānak. According to their genres, these texts highlight either the theological, narrative, or practical (namely, from the perspective of healing) aspects of pregnancy. An intriguing feature …
The Relationship Between Anemia, Chronic Energy Deficiency, Knowledge, And Other Factors And Anc Attendance Among Pregnant Women In Bogor City And Regency 2025, Winfried Ichtussend Hartnajaya Chrisna, Ratu Ayu Dewi Sartika, Nurul Dina Rahmawati, Daden Setiawan
The Relationship Between Anemia, Chronic Energy Deficiency, Knowledge, And Other Factors And Anc Attendance Among Pregnant Women In Bogor City And Regency 2025, Winfried Ichtussend Hartnajaya Chrisna, Ratu Ayu Dewi Sartika, Nurul Dina Rahmawati, Daden Setiawan
Indonesian Journal of Public Health Nutrition (IJPHN)
Antenatal Care (ANC) is a comprehensive health service to optimize pregnancy outcomes. In 2023 in Bogor City, the ANC K6 coverage rate has reached the target (98.63%), but this is not the case with the coverage in Bogor Regency (62.25%). ANC visits that do not reach the standard can be influenced by predisposing factors, supporting factors, and health needs factors. The inequality that occurs can hinder efforts to reduce maternal mortality. This study aims to determine the relationship between knowledge and other factors with ANC visits in Bogor City and Regency in 2025. This study is quantitative with a cross-sectional …
Determinants Of Abdominal Obesity In Adults (19 – 44 Years Old) In Riau Islands Province (Analysis Of Ski 2023 Data), Hanifah Mulia Rachman, Triyanti Triyanti, Ratu Ayu Dewi Sartika, Kusharisupeni Djokosujono
Determinants Of Abdominal Obesity In Adults (19 – 44 Years Old) In Riau Islands Province (Analysis Of Ski 2023 Data), Hanifah Mulia Rachman, Triyanti Triyanti, Ratu Ayu Dewi Sartika, Kusharisupeni Djokosujono
Indonesian Journal of Public Health Nutrition (IJPHN)
Abdominal obesity is a condition characterized by excessive fat accumulation in the abdominal region, which can increases the risk of type 2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. In 2023, Riau Islands Province recorded the highest prevalence of abdominal obesity in the island of Sumatra, at 42.5%. This study aimed to analyze the determinants of abdominal obesity among adults aged 19–44 years in Riau Islands Province based on gender, using secondary data from the 2023 Indonesia Health Survey (SKI). A total of 3,466 respondents were analyzed using chi-square tests and multiple logistic regression. The results showed that the prevalence …
Perceived Benefits And Side Effect Of High-Fiber, High-Protein Meal Replacements In Weight Loss Programs, Esti Nurwanti, Harry Fl Muhammad, Naufal M. Nurdin
Perceived Benefits And Side Effect Of High-Fiber, High-Protein Meal Replacements In Weight Loss Programs, Esti Nurwanti, Harry Fl Muhammad, Naufal M. Nurdin
Indonesian Journal of Public Health Nutrition (IJPHN)
Obesity is a major risk factor for chronic diseases and early mortality. Although dietary counseling is essential in managing obesity, maintaining a calorie deficit and preventing weight regain remain difficult. Functional foods like high-protein, high-fiber meal replacements may enhance adherence and support weight loss. This randomized controlled trial evaluated the subjective outcomes of a weight loss program incorporating a protein- and fiber-enriched meal replacement among 73 overweight women aged 20–30 years. Participants were randomized to an intervention group (n=38), receiving dietary counseling plus one daily meal replacement, or a control group (n=35), receiving counseling alone. Both groups followed an 8-week …
Analysis Of Macronutrient Content, Antioxidant Activity, And Organoleptic Quality Of Snack From Jackfruit Seed Flour (Artocarpus Heterophyllus) And Pigeon Pea Flour (Cajanus Cajanus) As A Snack For Patients With Type 2 Diabetes Mellitus, Maya Siwi Tri Nugroho Heni, Tesa Rafkhani
Analysis Of Macronutrient Content, Antioxidant Activity, And Organoleptic Quality Of Snack From Jackfruit Seed Flour (Artocarpus Heterophyllus) And Pigeon Pea Flour (Cajanus Cajanus) As A Snack For Patients With Type 2 Diabetes Mellitus, Maya Siwi Tri Nugroho Heni, Tesa Rafkhani
Indonesian Journal of Public Health Nutrition (IJPHN)
Type 2 diabetes mellitus characterized by chronic hyperglycemia and oxidative stress. Snack bars with functional ingredients such as legumes may help regulate blood glucose levels. Jackfruit seeds and pigeon peas are sources of protein, complex carbohydrates, and bioactive compounds. This study aimed to analyze macronutrient content, antioxidant activity, and organoleptic quality of jackfruit seeds and pigeon pea flour snack bars. This study used a completely randomized design (CRD) one factor with two replications. The proportions of jackfruit seeds and pigeon pea flour are: F1 (30%:70%), F2 (40%:60%), F3 (50%:50%). Macronutrient content was analyzed using proximate analysis, antioxidant activity using the …
Pathways Linking Green Digital Transformation To Sustainable Development Through Knowledge Sharing And Dynamic Capabilities, Imane Belyamani, Manar Fawzi Bani Mfarrej, Syed Zamberi Ahmad, Abdul Rahim Abu Bakar
Pathways Linking Green Digital Transformation To Sustainable Development Through Knowledge Sharing And Dynamic Capabilities, Imane Belyamani, Manar Fawzi Bani Mfarrej, Syed Zamberi Ahmad, Abdul Rahim Abu Bakar
All Works
This study explores how Green Digital Transformation (GDT) affects Sustainable Development Performance (SDP), with a particular focus on the mediating roles of Green Knowledge Sharing (GKS) and Green Dynamic Capabilities (GDC). Drawing upon the Natural Resource-Based View (NRBV) and Knowledge-Based View (KBV), the research develops and empirically tests an integrative model using data from 386 SMEs in the UAE’s innovation-driven industries. Findings from Partial Least Squares-Structural Equation Modeling (PLS-SEM) reveal that GDT significantly improves SDP, both directly and through the mediating influences of GKS and GDC. GKS acts as a key enabler, transforming digital investments into innovation and capability enhancement, …
Scales For Rating The Behavioral Characteristics Of Superior Students: A Preliminary Examination Of The Psychometric Properties Of The Greek Version Of The First Four Scales: Learning, Creativity, Motivation, And Leadership Scale, Eleni Rachanioti, Theodora Foti, Aikaterini Rafaella Geitona, Anastasia Tzalla, Anna Dougali, Olga Fragkomichelaki, Christina Bourmpou, Maria Staikopoulou, Aphrodite Papantoniou, Fotini Varlami, Irene Dinaki, Maria Tsiountala, Konstantinos Staikopoulos, Magda Dinou, Effie Katsadima, Tryfon Mavropalias, Harilaos Zaragas, Efthymia Efthymiou, Dimitra Katsarou, Georgios Kougioumtzis, Despina Moraitou, Maria Sofologi, Georgia Papantoniou
Scales For Rating The Behavioral Characteristics Of Superior Students: A Preliminary Examination Of The Psychometric Properties Of The Greek Version Of The First Four Scales: Learning, Creativity, Motivation, And Leadership Scale, Eleni Rachanioti, Theodora Foti, Aikaterini Rafaella Geitona, Anastasia Tzalla, Anna Dougali, Olga Fragkomichelaki, Christina Bourmpou, Maria Staikopoulou, Aphrodite Papantoniou, Fotini Varlami, Irene Dinaki, Maria Tsiountala, Konstantinos Staikopoulos, Magda Dinou, Effie Katsadima, Tryfon Mavropalias, Harilaos Zaragas, Efthymia Efthymiou, Dimitra Katsarou, Georgios Kougioumtzis, Despina Moraitou, Maria Sofologi, Georgia Papantoniou
All Works
The Scales for Rating the Behavioral Characteristics of Superior Students (SRBCSS; Renzulli et al., 2010) are notable for incorporating teachers’ informed evaluations in identifying gifted students. Teachers’ close interactions with students enable them to make meaningful judgments, and the SRBCSS provides a structured method to guide and strengthen their nominations. The aim of the present study was to gain insight into the psychometric properties of the Greek version of the first four Scales for Rating the Behavioral Characteristics of Superior Students (SRBCSS), which assess various dimensions of giftedness. One hundred and forty-five (145) Greek primary and secondary education school (elementary …
Runx2 Cooperates With Srebp1 To Rewire Cancer Metabolism And Promote Aggressiveness, Emanuele Vitale, Mila Gugnoni, Veronica Manicardi, Silvia Muccioli, Federica Torricelli, Benedetta Donati, Simonetta Piana, Gloria Manzotti, Elisa Salviato, Francesca Reggiani, Cristian Ascione, Rebecca Vezzani, Moira Ragazzi, Mattia Forcato, Oriana Romano, Silvio Bicciato, Aaron Goldman, Marco Tigano, Alessia Ciarrocchi
Runx2 Cooperates With Srebp1 To Rewire Cancer Metabolism And Promote Aggressiveness, Emanuele Vitale, Mila Gugnoni, Veronica Manicardi, Silvia Muccioli, Federica Torricelli, Benedetta Donati, Simonetta Piana, Gloria Manzotti, Elisa Salviato, Francesca Reggiani, Cristian Ascione, Rebecca Vezzani, Moira Ragazzi, Mattia Forcato, Oriana Romano, Silvio Bicciato, Aaron Goldman, Marco Tigano, Alessia Ciarrocchi
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
Embryonic Transcription Factors (TFs) are often reactivated in cancer, driving developmental gene programs that support phenotypic plasticity. Metabolic adaptation fuels this plasticity by supplying energy and molecular building blocks for growth. RUNX2, the master regulator of bone morphogenesis, is ectopically expressed in epithelial cancer, promoting metastasis through trans-differentiation processes like Epithelial-to-Mesenchymal Transition (EMT) and osteomimicry. By combining omics data with functional validation, we demonstrated that RUNX2 drives cancer cell metabolic rewiring by repressing mitochondrial respiration while promoting anabolic processes. We showed that RUNX2 upregulates key genes of lipid biosynthesis by regulating and cooperating with SREBP1. In vivo expression analysis in …
Re: 3rd Quarter 2025 – Interim Site-Wide Surface Water Monitoring Data Report Silver Bow Creek Butte Area Npl Site, Butte Priority Soils Operable Unit Consent Decree-Civil Action No. Cv 89-039-Bu-She, Josh Bryson
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Induction Of Myelopoiesis By Candida Dubliniensis Drives Protective Trained Immunity Against Sepsis In A Card9-Dependent Manner, Shannon Esher Righi, Elizabeth A. Lilly, Amanda J. Harriett, Patrick W. Daly, Maryjane Jones, Chad Steele, Mairi C. Noverr, Paul L. Fidel
Induction Of Myelopoiesis By Candida Dubliniensis Drives Protective Trained Immunity Against Sepsis In A Card9-Dependent Manner, Shannon Esher Righi, Elizabeth A. Lilly, Amanda J. Harriett, Patrick W. Daly, Maryjane Jones, Chad Steele, Mairi C. Noverr, Paul L. Fidel
School of Dentistry Faculty Publications
Trained immunity is a long-term functional reprogramming of innate cells that allows for the formation of immune memory akin to adaptive responses, but with a more rapid nonspecific response. We recently identified an anti-inflammatory trained immunity response, termed trained tolerogenic immunity (TTI), induced by low virulence Candida dubliniensis, that protects against acute lethal polymicrobial sepsis via myeloid-derived suppressor cells (MDSCs). Trained immunity and MDSCs arise following hematopoietic stem and progenitor cell (HSPC) expansion in the bone marrow. Here, we show that C. dubliniensis induces inoculum-dependent protection and HSPC expansion, whereas depletion of HSPCs following C. dubliniensis immunization abrogates protection. We …